Homo sapiens

20 known processes

ACTN3

actinin, alpha 3

(Aliases: MGC117005,MGC117002)

ACTN3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle system processGO:0003012810.759
muscle contractionGO:0006936730.755
skeletal muscle contractionGO:0003009160.647
striated muscle contractionGO:0006941520.626
actin filament based movementGO:0030048170.449
atrial cardiac muscle tissue morphogenesisGO:005500910.407
muscle structure developmentGO:0061061980.356
purine ribonucleotide catabolic processGO:00091544040.349
system processGO:00030083490.335
heart contractionGO:0060047620.334
cardiac muscle contractionGO:0060048340.302
musculoskeletal movementGO:0050881170.289
circulatory system developmentGO:00723592620.259
purine containing compound catabolic processGO:00725234110.259
actin filament based processGO:00300292240.247
glycosyl compound catabolic processGO:19016584130.238
circulatory system processGO:00030131130.236
heart processGO:0003015620.227
regulation of muscle contractionGO:0006937450.225
regulation of system processGO:00440571010.224
actin mediated cell contractionGO:0070252120.206
striated muscle tissue developmentGO:0014706590.180
muscle tissue developmentGO:0060537620.178
regulation of muscle system processGO:0090257530.176
atrial cardiac muscle tissue developmentGO:000322810.169
multicellular organismal movementGO:0050879170.167
ribonucleoside catabolic processGO:00424544060.166
purine ribonucleoside monophosphate metabolic processGO:00091671860.161
cardiovascular system developmentGO:00723582620.153
cardiac ventricle developmentGO:0003231230.153
nucleoside triphosphate metabolic processGO:00091414220.152
atp catabolic processGO:00062001570.151
purine ribonucleoside monophosphate catabolic processGO:00091691580.149
nucleoside phosphate catabolic processGO:19012924120.143
purine nucleoside catabolic processGO:00061523980.138
heart developmentGO:0007507950.136
cell developmentGO:00484683280.133
purine ribonucleoside triphosphate metabolic processGO:00092054110.133
voluntary skeletal muscle contractionGO:000301010.132
regulation of striated muscle contractionGO:0006942370.132
purine nucleotide catabolic processGO:00061954050.108
purine nucleoside monophosphate catabolic processGO:00091281580.108
ribonucleoside monophosphate metabolic processGO:00091611870.107
ribonucleoside triphosphate metabolic processGO:00091994120.107
purine nucleoside triphosphate catabolic processGO:00091463920.106
muscle organ morphogenesisGO:0048644190.103
cardiac ventricle morphogenesisGO:0003208200.103
nucleoside triphosphate catabolic processGO:00091433940.102
anatomical structure formation involved in morphogenesisGO:00486462840.100
purine ribonucleoside metabolic processGO:00461284370.099
blood circulationGO:00080151130.098
cardiac muscle tissue developmentGO:0048738390.096
actin cytoskeleton organizationGO:00300362070.095
purine ribonucleoside triphosphate catabolic processGO:00092073910.095
ribonucleotide catabolic processGO:00092614050.092
nucleoside catabolic processGO:00091644080.090
organ morphogenesisGO:00098871470.089
cardiac muscle tissue morphogenesisGO:0055008180.088
nucleotide catabolic processGO:00091664080.086
ribonucleoside triphosphate catabolic processGO:00092033910.085
nucleoside monophosphate metabolic processGO:00091231910.085
nucleoside monophosphate catabolic processGO:00091251590.084
atp metabolic processGO:00460341760.083
purine ribonucleoside catabolic processGO:00461303980.083
muscle organ developmentGO:0007517560.081
muscle cell differentiationGO:0042692630.079
purine nucleoside triphosphate metabolic processGO:00091444120.078
cardiac muscle cell contractionGO:008600340.078
ribonucleoside monophosphate catabolic processGO:00091581580.075
regulation of cardiac muscle contractionGO:0055117330.072
cellular component assembly involved in morphogenesisGO:0010927730.072
regulation of heart contractionGO:0008016500.072
cellular component morphogenesisGO:00329893140.070
striated muscle cell differentiationGO:0051146430.065
regulation of blood circulationGO:1903522590.065
heart morphogenesisGO:0003007480.065
organophosphate catabolic processGO:00464344300.062
tissue morphogenesisGO:0048729960.062
purine nucleoside monophosphate metabolic processGO:00091261860.062
muscle tissue morphogenesisGO:0060415190.060
twitch skeletal muscle contractionGO:001472110.058
biological adhesionGO:00226103310.058
cellular amino acid metabolic processGO:00065201160.057
post embryonic developmentGO:000979120.055
locomotory behaviorGO:000762610.055
regulation of cellular ketone metabolic processGO:0010565500.053
cellular amine metabolic processGO:0044106410.053
response to abiotic stimulusGO:00096283360.052
organelle assemblyGO:00709251760.051
cell adhesionGO:00071553250.051
chromatin organizationGO:00063253510.050
cellular ion homeostasisGO:00068731680.049
cell morphogenesisGO:00009022960.047
muscle cell developmentGO:0055001290.047
ventricular cardiac muscle tissue developmentGO:0003229140.047
ventricular cardiac muscle tissue morphogenesisGO:0055010140.046
multicellular organismal agingGO:001025930.045
positive regulation of cellular component organizationGO:00511303760.042
amine metabolic processGO:0009308440.042
regulation of anatomical structure morphogenesisGO:00226032860.042
mitotic cell cycle processGO:19030472860.042
positive regulation of catabolic processGO:00098963100.041
micturitionGO:006007330.041
cell junction organizationGO:0034330790.041
mitotic cell cycleGO:00002783260.041
regulation of cellular component movementGO:00512703340.041
carbohydrate metabolic processGO:00059752070.041
neuromuscular junction developmentGO:000752830.040
ion homeostasisGO:00508012300.040
regulation of cellular amine metabolic processGO:0033238110.040
negative regulation of multicellular organismal processGO:00512413170.039
cell projection organizationGO:00300302520.039
cardiac chamber morphogenesisGO:0003206260.038
muscle filament slidingGO:003004950.037
regulation of cell adhesionGO:00301551660.037
response to decreased oxygen levelsGO:0036293960.037
regulation of protein localizationGO:00328802960.036
inorganic cation transmembrane transportGO:00986621940.036
cation transmembrane transportGO:00986552380.035
transmembrane transportGO:00550853990.035
protein catabolic processGO:00301633250.035
regulation of cellular amino acid metabolic processGO:000652160.035
oogenesisGO:004847720.034
determination of adult lifespanGO:000834020.034
adult locomotory behaviorGO:000834410.034
immune responseGO:00069553070.034
enzyme linked receptor protein signaling pathwayGO:00071673030.033
single organism carbohydrate metabolic processGO:00447231930.032
regulation of nucleoside metabolic processGO:00091182090.032
negative regulation of phosphorus metabolic processGO:00105632670.032
cellular chemical homeostasisGO:00550821800.032
response to radiationGO:00093141510.032
positive regulation of transportGO:00510503360.031
cellular macromolecule catabolic processGO:00442653800.031
cellular divalent inorganic cation homeostasisGO:00725031280.031
inorganic ion transmembrane transportGO:00986602310.031
segmentationGO:003528240.031
cardiac chamber developmentGO:0003205300.031
negative regulation of phosphate metabolic processGO:00459362670.031
regulation of purine nucleotide catabolic processGO:00331212050.031
positive regulation of nucleotide metabolic processGO:00459812300.031
regulation of nucleotide catabolic processGO:00308112050.030
regulation of cell differentiationGO:00455953930.030
rho protein signal transductionGO:0007266260.030
skeletal muscle fiber developmentGO:0048741120.030
regulation of nucleotide metabolic processGO:00061402690.030
positive regulation of cellular catabolic processGO:00313312840.030
negative regulation of catalytic activityGO:00430863350.030
ion transmembrane transportGO:00342203380.029
cell substrate adhesionGO:00315891320.029
response to inorganic substanceGO:00100351270.029
positive regulation of cellular amine metabolic processGO:003324070.029
skeletal muscle thin filament assemblyGO:003024030.029
regulation of purine nucleotide metabolic processGO:19005422640.029
cell cell junction organizationGO:0045216690.029
actomyosin structure organizationGO:0031032590.029
female gamete generationGO:000729220.028
chromatin modificationGO:00165682980.028
detection of stimulusGO:0051606850.028
striated muscle cell developmentGO:0055002270.028
negative regulation of protein metabolic processGO:00512483910.028
negative regulation of cellular protein metabolic processGO:00322693530.028
regulation of ion transmembrane transporter activityGO:0032412720.028
signal transduction by phosphorylationGO:00230142970.027
oxidation reduction processGO:00551143960.027
histone modificationGO:00165702510.027
positive regulation of nucleotide catabolic processGO:00308131850.027
apoptotic signaling pathwayGO:00971902680.027
cellular ketone metabolic processGO:0042180800.026
nervous system developmentGO:00073992930.026
regulation of acetylcholine gated cation channel activityGO:190304810.026
ras protein signal transductionGO:0007265730.026
covalent chromatin modificationGO:00165692540.026
regulation of transmembrane transporter activityGO:0022898740.025
organelle fissionGO:00482851490.025
regulation of transmembrane transportGO:00347621390.025
regulation of actin filament based processGO:00329701410.025
calcium ion homeostasisGO:00550741220.025
matingGO:000761810.025
regulation of protein kinase activityGO:00458592890.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
positive regulation of purine nucleotide catabolic processGO:00331231850.025
metal ion transportGO:00300012720.025
positive regulation of nucleoside metabolic processGO:00459791860.025
regulation of cell motilityGO:20001452990.025
vasculature developmentGO:00019441810.025
protein oligomerizationGO:00512591730.024
chemical homeostasisGO:00488783060.024
cellular protein complex assemblyGO:00436231880.024
positive regulation of cell differentiationGO:00455972110.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of hydrolase activityGO:00513453310.024
cellular protein catabolic processGO:00442572610.024
negative regulation of acetylcholine gated cation channel activityGO:190304910.024
positive regulation of cell proliferationGO:00082843010.024
cellular response to dna damage stimulusGO:00069743790.024
protein localization to organelleGO:00333652800.023
regulation of dna metabolic processGO:00510521530.023
cellular response to abiotic stimulusGO:00712141170.023
cation transportGO:00068123310.023
regulation of kinase activityGO:00435493140.023
regulation of transferase activityGO:00513383550.023
cellular macromolecular complex assemblyGO:00346223240.023
response to hypoxiaGO:0001666960.023
multicellular organismal signalingGO:0035637340.022
negative regulation of muscle contractionGO:004593230.022
action potentialGO:0001508340.022
regulation of cell cycleGO:00517263930.022
response to oxidative stressGO:00069791210.022
negative regulation of protein modification processGO:00314002000.022
regulation of membrane potentialGO:0042391950.022
circadian behaviorGO:004851220.022
cation homeostasisGO:00550801890.022
tachykinin receptor signaling pathwayGO:000721730.021
cytoplasmic transportGO:00164823790.021
negative regulation of hydrolase activityGO:00513461820.021
positive regulation of protein phosphorylationGO:00019343130.021
rhythmic behaviorGO:000762220.021
negative regulation of cellular component organizationGO:00511292350.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
response to oxygen levelsGO:00704821000.021
positive regulation of developmental processGO:00510943140.021
response to activityGO:001482300.021
regulation of proteolysisGO:00301622930.021
regulation of cellular component biogenesisGO:00440872810.021
small gtpase mediated signal transductionGO:0007264780.021
cell growthGO:00160491600.020
myoblast fusionGO:000752010.020
syncytium formation by plasma membrane fusionGO:000076820.020
growthGO:00400072020.020
nuclear divisionGO:00002801280.020
anterior posterior axis specificationGO:000994820.020
negative regulation of programmed cell deathGO:00430693210.020
cell cycle phase transitionGO:00447701730.020
actin filament organizationGO:00070151280.020
cellular cation homeostasisGO:00300031630.020
positive regulation of programmed cell deathGO:00430682490.020
response to light stimulusGO:0009416870.019
blastoderm segmentationGO:000735020.019
positive regulation of organelle organizationGO:00106381950.019
microtubule based processGO:00070172100.019
regulation of mapk cascadeGO:00434082620.019
negative regulation of phosphorylationGO:00423261740.019
mitotic nuclear divisionGO:00070671190.019
single organism membrane organizationGO:00448022680.019
tissue migrationGO:00901301190.019
epithelium developmentGO:00604292270.019
positive regulation of apoptotic processGO:00430652460.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of response to external stimulusGO:00321012220.019
regenerationGO:003109940.019
mitotic cell cycle phase transitionGO:00447721620.019
negative regulation of transportGO:00510511760.019
regulation of atpase activityGO:0043462250.019
membrane organizationGO:00610242920.018
cell junction assemblyGO:0034329670.018
cytokine productionGO:00018162470.018
regulation of ion transportGO:00432691890.018
negative regulation of intracellular signal transductionGO:19025321830.018
nucleocytoplasmic transportGO:00069131760.018
positive regulation of aldosterone metabolic processGO:003234620.018
mapk cascadeGO:00001652880.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
positive regulation of cellular component movementGO:00512721810.018
dna repairGO:00062811980.018
regulation of intracellular transportGO:00323861950.018
negative regulation of cellular amine metabolic processGO:003323930.018
av node cell to bundle of his cell communicationGO:008606740.018
regulation of cell migrationGO:00303342890.018
pulmonary valve formationGO:000319310.018
regulation of atp catabolic processGO:1903289250.018
regulation of skeletal muscle contractionGO:001481930.018
cellular response to growth factor stimulusGO:00713631970.017
modification dependent protein catabolic processGO:00199412090.017
generation of neuronsGO:00486991520.017
hindbrain developmentGO:003090230.017
sleepGO:003043120.017
modification dependent macromolecule catabolic processGO:00436322120.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
memoryGO:000761330.017
dephosphorylationGO:00163112090.017
intracellular protein transportGO:00068862700.017
regulation of establishment of protein localizationGO:00702012420.017
spermatid differentiationGO:004851540.017
protein processingGO:00164852260.017
proteasomal protein catabolic processGO:00104981760.017
regulation of transporter activityGO:0032409820.017
protein maturationGO:00516042330.017
negative regulation of protein phosphorylationGO:00019331400.017
regulation of ion transmembrane transportGO:00347651320.016
ubiquitin dependent protein catabolic processGO:00065112060.016
maintenance of locationGO:00512351120.016
regulation of atp metabolic processGO:1903578290.016
negative regulation of apoptotic processGO:00430663160.016
positive regulation of mapk cascadeGO:00434101900.016
behaviorGO:00076101120.016
cell projection assemblyGO:00300311260.016
negative regulation of cell cycleGO:00457861930.016
regulation of cell cycle processGO:00105642660.016
regulation of mitotic cell cycleGO:00073461890.016
epithelium migrationGO:00901321190.016
monovalent inorganic cation transportGO:00156721280.016
positive regulation of hormone biosynthetic processGO:004688640.016
single organism cellular localizationGO:19025803320.016
rna processingGO:00063962550.016
regulation of cytokine productionGO:00018172320.016
postsynaptic membrane organizationGO:000194120.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
regulation of protein transportGO:00512232130.016
synaptic transmission cholinergicGO:000727120.016
skeletal muscle tissue developmentGO:0007519240.016
positive regulation of cell deathGO:00109422630.016
spermatid developmentGO:000728640.016
cellular response to oxygen containing compoundGO:19017012760.016
single organismal cell cell adhesionGO:00163371480.016
synaptic transmission involved in micturitionGO:006008420.016
protein targetingGO:00066051870.016
negative regulation of striated muscle contractionGO:004598820.015
posttranscriptional regulation of gene expressionGO:00106082130.015
divalent inorganic cation homeostasisGO:00725071360.015
positive regulation of ion transmembrane transporter activityGO:0032414290.015
tissue regenerationGO:004224630.015
compound eye developmentGO:004874910.015
cellular metal ion homeostasisGO:00068751460.015
anterior posterior axis specification embryoGO:000859520.015
regulation of protein maturationGO:19033171500.015
protein modification by small protein conjugationGO:00324463420.015
response to growth factorGO:00708482050.015
regulation of protein catabolic processGO:00421761550.015
response to fungusGO:000962040.015
epidermis morphogenesisGO:004873030.015
regulation of cell growthGO:00015581350.015
response to oxygen containing compoundGO:19017003690.015
glycoprotein metabolic processGO:00091001100.015
carbohydrate derivative biosynthetic processGO:19011372070.015
regulation of cell projection organizationGO:00313441070.015
regulation of feeding behaviorGO:006025930.015
negative regulation of catabolic processGO:00098951040.015
carbohydrate catabolic processGO:0016052360.015
metencephalon developmentGO:002203720.014
somatic muscle developmentGO:000752510.014
nitrogen compound transportGO:00717051910.014
anatomical structure homeostasisGO:00602491000.014
cellular homeostasisGO:00197251960.014
nuclear transportGO:00511691790.014
positive regulation of kinase activityGO:00336742040.014
neurological system processGO:00508771630.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
negative regulation of growthGO:0045926970.014
wound healingGO:00420601150.014
sensory perceptionGO:00076001030.014
cerebellum developmentGO:002154920.014
alcohol metabolic processGO:00060661140.014
defense responseGO:00069523150.014
regulation of cytoskeleton organizationGO:00514931770.014
negative regulation of transferase activityGO:00513481240.014
potassium ion transportGO:0006813620.014
regulation of carbohydrate metabolic processGO:0006109540.014
response to cytokineGO:00340972320.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
oocyte developmentGO:004859910.014
protein ubiquitinationGO:00165673140.014
negative regulation of developmental processGO:00510932470.014
cardiac muscle cell action potential involved in contractionGO:0086002210.014
regulation of endopeptidase activityGO:00525481700.014
negative regulation of cell growthGO:0030308830.014
protein tetramerizationGO:0051262470.014
glycoprotein biosynthetic processGO:0009101910.013
mitochondrion organizationGO:00070051560.013
cellular potassium ion transportGO:0071804600.013
gtp catabolic processGO:00061842370.013
regulation of intracellular protein transportGO:00331571230.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of protein processingGO:00706131500.013
regulation of actin cytoskeleton organizationGO:00329561160.013
positive regulation of proteolysisGO:00458621420.013
cell part morphogenesisGO:00329901370.013
negative regulation of cell deathGO:00605483450.013
monocarboxylic acid metabolic processGO:00327871850.013
muscle fiber developmentGO:0048747160.013
striated muscle myosin thick filament assemblyGO:007168820.013
regulation of ras protein signal transductionGO:00465781550.013
cellular carbohydrate metabolic processGO:0044262840.013
tripartite regional subdivisionGO:000735120.013
potassium ion transmembrane transportGO:0071805600.013
innate immune responseGO:00450871780.013
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.013
gtp metabolic processGO:00460392390.013
oocyte differentiationGO:000999420.013
positive regulation of cellular component biogenesisGO:00440891580.013
neurogenesisGO:00220081690.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
regulation of body fluid levelsGO:0050878990.013
regulation of mitotic cell cycle phase transitionGO:19019901180.013
detection of chemical stimulus involved in sensory perceptionGO:0050907330.013
positive regulation of protein transportGO:00512221350.013
myosin filament assemblyGO:003103420.013
positive regulation of immune system processGO:00026842830.013
neuroblast proliferationGO:000740540.013
guanosine containing compound catabolic processGO:19010692390.013
hexose metabolic processGO:0019318550.013
negative regulation of organelle organizationGO:00106391260.013
establishment of protein localization to organelleGO:00725941720.013
regulation of immune responseGO:00507762010.013
blood vessel developmentGO:00015681720.012
regulation of peptidase activityGO:00525471800.012
guanosine containing compound metabolic processGO:19010682440.012
myosin filament organizationGO:003103320.012
regulation of cellular protein catabolic processGO:1903362960.012
protein homooligomerizationGO:00512601000.012
response to organic cyclic compoundGO:00140702040.012
head developmentGO:00603221080.012
positive regulation of phosphorylationGO:00423273940.012
small molecule biosynthetic processGO:00442831570.012
microtubule cytoskeleton organizationGO:00002261760.012
reactive oxygen species metabolic processGO:0072593750.012
negative regulation of protein kinase activityGO:0006469980.012
regulation of growthGO:00400081650.012
organonitrogen compound biosynthetic processGO:19015662000.012
cell cell signalingGO:00072671550.012
cellular component disassemblyGO:0022411920.012
reactive nitrogen species metabolic processGO:200105730.012
establishment of protein localization to membraneGO:00901501210.012
regulation of gtpase activityGO:00430871800.012
cellular response to endogenous stimulusGO:00714953360.012
sensory perception of light stimulusGO:0050953350.012
cell substrate adherens junction assemblyGO:0007045300.012
negative regulation of kinase activityGO:00336731060.012
epithelial cell differentiationGO:00308551410.012
negative regulation of proteolysisGO:00458611320.012
protein localization to nucleusGO:00345041360.012
negative regulation of cell proliferationGO:00082852280.012
regulation of cell morphogenesisGO:00226041530.012
neuron projection developmentGO:00311751060.012
response to external biotic stimulusGO:00432072610.012
thymus developmentGO:004853830.012
taxisGO:00423301570.012
neurotransmitter secretionGO:000726940.012
negative regulation of cellular catabolic processGO:0031330830.012
membrane repolarizationGO:0086009230.012
regulation of cell developmentGO:00602841610.012
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.012
negative regulation of protein processingGO:00109551420.012
sex determinationGO:000753030.011
actin myosin filament slidingGO:003327560.011
ameboidal type cell migrationGO:00016671350.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
endocytosisGO:00068971590.011
protein localization to membraneGO:00726571600.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of circadian sleep wake cycle sleepGO:004518720.011
positive regulation of ion transportGO:0043270870.011
meiosis iGO:000712740.011
lipid metabolic processGO:00066293810.011
regulation of epithelial cell proliferationGO:00506781130.011
negative regulation of cytosolic calcium ion concentrationGO:005148110.011
sensory organ developmentGO:0007423520.011
regulation of protein targetingGO:1903533910.011
endomembrane system organizationGO:00102561960.011
positive regulation of synaptic transmissionGO:005080640.011
cardiac conductionGO:0061337230.011
response to organonitrogen compoundGO:00102431560.011
single organism cell adhesionGO:00986021790.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011

ACTN3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.784
muscular diseaseDOID:00800001140.784
muscle tissue diseaseDOID:661130.716
cardiovascular system diseaseDOID:12871060.165
intrinsic cardiomyopathyDOID:0060036500.165
cardiomyopathyDOID:0050700500.165
heart diseaseDOID:114680.165
myopathyDOID:4231040.165
disease of metabolismDOID:00146672950.054
distal arthrogryposisDOID:005064690.048
muscular dystrophyDOID:9884510.042
nervous system diseaseDOID:8634310.029
sensory system diseaseDOID:00501552030.029
central nervous system diseaseDOID:3311860.021
inherited metabolic disorderDOID:6552420.021
eye and adnexa diseaseDOID:14921500.015
eye diseaseDOID:56141490.015
disease of cellular proliferationDOID:145661740.014
auditory system diseaseDOID:2742530.013
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
neurodegenerative diseaseDOID:12891020.013
retinal diseaseDOID:56791180.012
acquired metabolic diseaseDOID:0060158580.012
immune system diseaseDOID:29141550.012
hypertrophic cardiomyopathyDOID:11984210.011