Homo sapiens

59 known processes

DMPK

dystrophia myotonica-protein kinase

(Aliases: DM,MDPK,MT-PK,DMK,DM1,DM1PK)

DMPK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
biological adhesionGO:00226103310.446
cell adhesionGO:00071553250.436
regulation of axon guidanceGO:190266730.301
regulation of cell differentiationGO:00455953930.285
Mouse
regulation of mesenchymal stem cell proliferationGO:190246010.264
purine nucleoside catabolic processGO:00061523980.264
purine containing compound catabolic processGO:00725234110.222
enzyme linked receptor protein signaling pathwayGO:00071673030.209
glycosyl compound catabolic processGO:19016584130.204
nucleoside triphosphate catabolic processGO:00091433940.198
ribonucleoside triphosphate catabolic processGO:00092033910.196
cell developmentGO:00484683280.196
oogenesisGO:004847720.176
muscle structure developmentGO:0061061980.171
Mouse
negative regulation of developmental processGO:00510932470.168
ribonucleoside catabolic processGO:00424544060.162
actin cytoskeleton organizationGO:00300362070.160
purine ribonucleoside triphosphate catabolic processGO:00092073910.155
positive regulation of catabolic processGO:00098963100.148
cellular response to endogenous stimulusGO:00714953360.147
nucleoside phosphate catabolic processGO:19012924120.143
multicellular organismal agingGO:001025930.139
system processGO:00030083490.138
positive regulation of developmental processGO:00510943140.135
regulation of cell adhesionGO:00301551660.128
neuromuscular junction developmentGO:000752830.127
spinal cord developmentGO:002151040.124
nucleoside triphosphate metabolic processGO:00091414220.124
regulation of gtp catabolic processGO:00331241800.124
purine nucleoside triphosphate metabolic processGO:00091444120.123
purine nucleoside triphosphate catabolic processGO:00091463920.123
cell projection organizationGO:00300302520.119
cellular response to growth factor stimulusGO:00713631970.118
calcium ion transportGO:00068161470.118
regulation of nucleotide metabolic processGO:00061402690.116
negative regulation of phosphorus metabolic processGO:00105632670.115
Human
taxisGO:00423301570.113
regulation of nucleotide catabolic processGO:00308112050.113
positive regulation of cell proliferationGO:00082843010.112
response to abiotic stimulusGO:00096283360.111
regulation of nucleoside metabolic processGO:00091182090.110
positive regulation of purine nucleotide catabolic processGO:00331231850.108
negative regulation of phosphate metabolic processGO:00459362670.107
Human
actin filament based processGO:00300292240.104
negative regulation of multicellular organismal processGO:00512413170.103
ribonucleoside triphosphate metabolic processGO:00091994120.103
metal ion transportGO:00300012720.102
Mouse
organophosphate catabolic processGO:00464344300.102
positive regulation of cellular component organizationGO:00511303760.101
guanosine containing compound metabolic processGO:19010682440.101
regulation of cellular component movementGO:00512703340.101
nucleoside catabolic processGO:00091644080.099
single organism cell adhesionGO:00986021790.098
regulation of cell motilityGO:20001452990.097
cellular component morphogenesisGO:00329893140.096
nucleotide catabolic processGO:00091664080.092
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.092
cellular macromolecule catabolic processGO:00442653800.090
Yeast
ribonucleotide catabolic processGO:00092614050.090
cell morphogenesisGO:00009022960.089
purine ribonucleotide catabolic processGO:00091544040.089
membrane organizationGO:00610242920.087
purine nucleotide catabolic processGO:00061954050.086
gtp catabolic processGO:00061842370.084
determination of adult lifespanGO:000834020.083
protein localization to membraneGO:00726571600.082
purine ribonucleoside triphosphate metabolic processGO:00092054110.081
gtp metabolic processGO:00460392390.079
single organismal cell cell adhesionGO:00163371480.078
organelle assemblyGO:00709251760.077
purine ribonucleoside catabolic processGO:00461303980.077
regulation of purine nucleotide metabolic processGO:19005422640.076
positive regulation of purine nucleotide metabolic processGO:19005442270.074
post embryonic developmentGO:000979120.074
negative regulation of apoptotic processGO:00430663160.072
neuron differentiationGO:00301821380.070
mitotic cell cycle processGO:19030472860.069
Yeast
regulation of gtpase activityGO:00430871800.069
heart developmentGO:0007507950.066
regulation of chemotaxisGO:0050920740.066
intracellular protein transportGO:00068862700.065
regulation of cell cycleGO:00517263930.065
Yeast
striated muscle cell differentiationGO:0051146430.064
Mouse
cellular response to oxygen containing compoundGO:19017012760.064
posttranscriptional regulation of gene expressionGO:00106082130.063
cellular macromolecular complex assemblyGO:00346223240.063
actin filament organizationGO:00070151280.062
guanosine containing compound catabolic processGO:19010692390.062
establishment of protein localization to membraneGO:00901501210.062
chemotaxisGO:00069351570.062
female gamete generationGO:000729220.061
positive regulation of mesenchymal stem cell differentiationGO:200074140.059
positive regulation of gtp catabolic processGO:00331261660.059
regulation of transferase activityGO:00513383550.059
Human
muscle tissue developmentGO:0060537620.058
inorganic ion transmembrane transportGO:00986602310.057
kidney developmentGO:0001822530.057
single organism membrane organizationGO:00448022680.056
regulation of anatomical structure morphogenesisGO:00226032860.056
regulation of establishment of protein localizationGO:00702012420.055
regulation of locomotionGO:00400123290.054
protein targetingGO:00066051870.052
vesicle mediated transportGO:00161923710.051
transforming growth factor beta productionGO:0071604140.050
ossificationGO:00015031210.050
negative regulation of protein metabolic processGO:00512483910.050
Human
regulation of cellular component biogenesisGO:00440872810.050
negative regulation of axon guidanceGO:190266810.050
muscle cell differentiationGO:0042692630.048
Mouse
cell type specific apoptotic processGO:00972851250.048
single organism cellular localizationGO:19025803320.048
regulation of bindingGO:00510981110.047
divalent inorganic cation transportGO:00725111580.047
positive regulation of nucleoside metabolic processGO:00459791860.047
regulation of cell migrationGO:00303342890.046
small gtpase mediated signal transductionGO:0007264780.046
striated muscle tissue developmentGO:0014706590.045
positive regulation of gtpase activityGO:00435471660.045
growthGO:00400072020.044
regulation of intracellular transportGO:00323861950.044
tissue morphogenesisGO:0048729960.044
rho protein signal transductionGO:0007266260.043
regulation of purine nucleotide catabolic processGO:00331212050.043
ion homeostasisGO:00508012300.043
Yeast Mouse
epithelium developmentGO:00604292270.042
calcium ion transmembrane transportGO:0070588760.042
urogenital system developmentGO:0001655650.041
divalent metal ion transportGO:00708381520.041
cytokine productionGO:00018162470.041
positive regulation of cell differentiationGO:00455972110.040
apoptotic signaling pathwayGO:00971902680.039
regulation of proteolysisGO:00301622930.038
oocyte differentiationGO:000999420.038
intrinsic apoptotic signaling pathwayGO:00971931270.038
secretionGO:00469032540.037
response to growth factorGO:00708482050.037
regulation of axon extension involved in axon guidanceGO:004884120.037
positive regulation of nucleotide metabolic processGO:00459812300.036
negative regulation of cellular protein metabolic processGO:00322693530.036
Human
neuron projection developmentGO:00311751060.036
nervous system developmentGO:00073992930.036
blood circulationGO:00080151130.036
negative regulation of programmed cell deathGO:00430693210.036
organophosphate biosynthetic processGO:00904071630.035
positive regulation of cellular catabolic processGO:00313312840.035
embryo developmentGO:00097901230.034
skeletal system developmentGO:0001501790.033
peptidyl tyrosine modificationGO:00182121700.033
organonitrogen compound biosynthetic processGO:19015662000.033
anatomical structure formation involved in morphogenesisGO:00486462840.033
mitotic cell cycleGO:00002783260.033
Yeast
negative regulation of cell differentiationGO:00455961710.033
chromatin organizationGO:00063253510.032
negative regulation of axonogenesisGO:005077140.032
ion transmembrane transportGO:00342203380.032
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.031
cellular ketone metabolic processGO:0042180800.031
regulation of intracellular protein transportGO:00331571230.031
regulation of stem cell differentiationGO:2000736560.031
regulation of response to external stimulusGO:00321012220.031
cellular response to transforming growth factor beta stimulusGO:0071560940.030
regulation of protein localizationGO:00328802960.030
Yeast
digestive tract developmentGO:0048565750.030
regulation of small gtpase mediated signal transductionGO:00510561560.030
wound healingGO:00420601150.030
negative regulation of cellular component movementGO:00512711060.030
regulation of hormone levelsGO:00108171250.029
regulation of cellular amino acid metabolic processGO:000652160.029
plasma membrane organizationGO:00070091150.028
connective tissue developmentGO:0061448390.028
regulation of cyclic nucleotide metabolic processGO:0030799630.028
cell activationGO:00017752130.028
negative regulation of cell deathGO:00605483450.028
positive regulation of protein phosphorylationGO:00019343130.028
response to hypoxiaGO:0001666960.028
platelet aggregationGO:0070527320.027
cellular response to dna damage stimulusGO:00069743790.027
negative regulation of hydrolase activityGO:00513461820.027
protein catabolic processGO:00301633250.027
neurogenesisGO:00220081690.027
cell morphogenesis involved in differentiationGO:00009041440.027
negative regulation of axon extensionGO:003051720.027
positive regulation of programmed cell deathGO:00430682490.027
regulation of cell cycle processGO:00105642660.027
Yeast
regulation of nervous system developmentGO:0051960880.027
response to oxygen levelsGO:00704821000.027
peptidyl lysine modificationGO:00182051440.026
negative regulation of cellular response to growth factor stimulusGO:0090288410.026
response to muscle stretchGO:003599430.026
negative regulation of intracellular signal transductionGO:19025321830.026
Human
cation transmembrane transportGO:00986552380.026
protein acylationGO:00435431380.026
hematopoietic or lymphoid organ developmentGO:00485341860.026
cell migration involved in gastrulationGO:004207410.026
cellular amino acid metabolic processGO:00065201160.026
regulation of protein transportGO:00512232130.026
protein localization to organelleGO:00333652800.026
regulation of protein catabolic processGO:00421761550.026
morphogenesis of embryonic epitheliumGO:001633140.025
cell divisionGO:00513011680.025
Yeast
regulation of cellular response to growth factor stimulusGO:0090287760.025
oocyte developmentGO:004859910.025
regulation of ras gtpase activityGO:00323181280.025
histone modificationGO:00165702510.025
mrna splicing via spliceosomeGO:0000398890.025
internal peptidyl lysine acetylationGO:0018393970.025
cation transportGO:00068123310.024
Mouse
forebrain neuron differentiationGO:002187930.024
cell substrate adhesionGO:00315891320.024
purine ribonucleoside metabolic processGO:00461284370.024
peptidyl tyrosine phosphorylationGO:00181081700.024
endosomal transportGO:00161971290.024
cellular protein catabolic processGO:00442572610.024
negative regulation of protein phosphorylationGO:00019331400.024
Human
neuron developmentGO:00486661130.024
prostate gland stromal morphogenesisGO:006074110.024
heart processGO:0003015620.024
osteoblast differentiationGO:0001649920.024
regulation of muscle cell differentiationGO:0051147310.024
Mouse
circulatory system developmentGO:00723592620.024
limbic system developmentGO:002176130.023
embryonic morphogenesisGO:0048598850.023
segmentationGO:003528240.023
regulation of proteasomal protein catabolic processGO:0061136870.023
positive regulation of cell cycleGO:00457871400.023
blastoderm segmentationGO:000735020.023
generation of neuronsGO:00486991520.023
nucleoside monophosphate metabolic processGO:00091231910.023
cytoplasmic transportGO:00164823790.022
regulation of cell developmentGO:00602841610.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
positive regulation of hydrolase activityGO:00513453310.022
rna splicingGO:00083801310.022
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.022
positive regulation of apoptotic processGO:00430652460.022
renal system developmentGO:0072001630.022
regulation of actin filament based processGO:00329701410.022
stem cell differentiationGO:0048863930.022
muscle cell developmentGO:0055001290.022
regulation of calcium ion transmembrane transporter activityGO:1901019280.021
regulation of body fluid levelsGO:0050878990.021
proteoglycan catabolic processGO:003016730.021
positive regulation of organelle organizationGO:00106381950.021
negative regulation of locomotionGO:00400131180.021
carbohydrate derivative biosynthetic processGO:19011372070.021
cardiac muscle contractionGO:0060048340.021
internal protein amino acid acetylationGO:00064751010.021
regulation of mapk cascadeGO:00434082620.021
Human
negative regulation of intracellular transportGO:0032387600.021
regulation of cytoskeleton organizationGO:00514931770.021
ubiquitin dependent protein catabolic processGO:00065112060.021
atp metabolic processGO:00460341760.020
cyclic nucleotide biosynthetic processGO:0009190610.020
muscle organ developmentGO:0007517560.020
proteasomal protein catabolic processGO:00104981760.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
mrna metabolic processGO:00160711750.020
Yeast
forebrain neuron developmentGO:002188420.020
detection of mechanical stimulusGO:005098240.020
regulation of transmembrane transportGO:00347621390.020
positive regulation of mesenchymal stem cell proliferationGO:190246210.020
cell cycle phase transitionGO:00447701730.020
homotypic cell cell adhesionGO:0034109470.020
inorganic cation transmembrane transportGO:00986621940.019
signal transduction by phosphorylationGO:00230142970.019
Human
maintenance of locationGO:00512351120.019
matingGO:000761810.019
developmental cell growthGO:0048588180.019
compound eye developmentGO:004874910.019
regulation of striated muscle tissue developmentGO:0016202260.019
chemical homeostasisGO:00488783060.019
Yeast Mouse
regulation of cell projection organizationGO:00313441070.019
cardiovascular system developmentGO:00723582620.019
regulation of behaviorGO:0050795820.019
regulation of ossificationGO:0030278580.019
negative regulation of cell growthGO:0030308830.019
cell growthGO:00160491600.019
axon extensionGO:0048675130.018
protein oligomerizationGO:00512591730.018
endomembrane system organizationGO:00102561960.018
histone acetylationGO:0016573930.018
cellular component assembly involved in morphogenesisGO:0010927730.018
positive regulation of ras gtpase activityGO:00323201170.018
nerve developmentGO:002167540.018
positive regulation of cell cycle processGO:00900681060.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
distal tubule developmentGO:007201740.018
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.018
protein localization to plasma membraneGO:0072659930.018
response to oxidative stressGO:00069791210.017
glycoprotein metabolic processGO:00091001100.017
chromatin modificationGO:00165682980.017
lipid metabolic processGO:00066293810.017
amine metabolic processGO:0009308440.017
negative regulation of phosphorylationGO:00423261740.017
Human
dephosphorylationGO:00163112090.017
modification dependent macromolecule catabolic processGO:00436322120.017
negative regulation of protein modification processGO:00314002000.017
Human
regulation of dephosphorylationGO:0035303960.016
regulation of cell morphogenesisGO:00226041530.016
negative regulation of cell motilityGO:20001461040.016
stem cell developmentGO:0048864690.016
detection of muscle stretchGO:003599520.016
regulation of protein targetingGO:1903533910.016
positive regulation of protein transportGO:00512221350.016
protein ubiquitinationGO:00165673140.016
negative regulation of catalytic activityGO:00430863350.016
Human
regulation of ion transmembrane transportGO:00347651320.016
regulation of mitotic cell cycleGO:00073461890.016
t cell selectionGO:004505840.016
regulation of rho gtpase activityGO:0032319660.016
cyclic nucleotide metabolic processGO:0009187820.016
platelet activationGO:0030168440.016
positive regulation of nucleotide catabolic processGO:00308131850.016
secretion by cellGO:00329402260.016
response to decreased oxygen levelsGO:0036293960.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.015
heart contractionGO:0060047620.015
response to oxygen containing compoundGO:19017003690.015
regulation of cellular protein catabolic processGO:1903362960.015
negative regulation of bindingGO:0051100570.015
mesenchymal stem cell proliferationGO:009716810.015
neuron projection morphogenesisGO:0048812500.015
regulation of cell growthGO:00015581350.015
cytokinesisGO:0000910960.015
Yeast
purine nucleotide biosynthetic processGO:0006164840.015
glycerolipid metabolic processGO:00464861070.015
blood vessel morphogenesisGO:00485141620.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
phospholipid metabolic processGO:0006644990.015
reproductive system developmentGO:0061458560.014
protein acetylationGO:00064731160.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
modification dependent protein catabolic processGO:00199412090.014
cell projection morphogenesisGO:00488581290.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
coagulationGO:0050817780.014
negative regulation of protein transportGO:0051224750.014
ras protein signal transductionGO:0007265730.014
negative regulation of protein kinase activityGO:0006469980.014
Human
positive regulation of locomotionGO:00400171860.014
developmental process involved in reproductionGO:0003006660.014
golgi vesicle transportGO:0048193800.014
response to external biotic stimulusGO:00432072610.014
positive regulation of axon extensionGO:004577340.014
cell chemotaxisGO:00603261120.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
peptidyl lysine acetylationGO:00183941010.013
blood coagulationGO:0007596760.013
purine containing compound biosynthetic processGO:0072522880.013
regulation of cellular response to stressGO:00801352440.013
stress activated mapk cascadeGO:0051403930.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
response to transforming growth factor betaGO:0071559940.013
translationGO:00064121320.013
regulation of protein serine threonine kinase activityGO:00719001790.013
Human
negative regulation of cell proliferationGO:00082852280.013
t cell differentiation in thymusGO:003307740.013
cellular response to abiotic stimulusGO:00712141170.013
cellular response to organic cyclic compoundGO:00714071270.013
regulation of calcium ion transportGO:0051924790.013
retina vasculature morphogenesis in camera type eyeGO:006129930.013
forebrain generation of neuronsGO:002187230.013
protein targeting to membraneGO:0006612420.013
negative regulation of hepatocyte growth factor receptor signaling pathwayGO:190220310.013
regulation of nucleocytoplasmic transportGO:0046822980.013
gland developmentGO:0048732480.013
receptor metabolic processGO:0043112810.013
positive regulation of cell deathGO:00109422630.012
rna processingGO:00063962550.012
negative regulation of cell migrationGO:00303361020.012
cellular response to decreased oxygen levelsGO:0036294510.012
immune responseGO:00069553070.012
ribonucleotide biosynthetic processGO:0009260810.012
syncytium formation by plasma membrane fusionGO:000076820.012
ribonucleoprotein complex biogenesisGO:00226131160.012
gamma delta t cell activationGO:004662930.012
neuron projection extensionGO:1990138140.012
erbb signaling pathwayGO:0038127440.012
digestive tract morphogenesisGO:0048546560.012
actomyosin structure organizationGO:0031032590.012
regulation of neuron projection developmentGO:0010975570.012
cellular response to organonitrogen compoundGO:00714171240.012
convergent extensionGO:006002610.012
regulation of kinase activityGO:00435493140.012
Human
stress activated protein kinase signaling cascadeGO:0031098940.012
glycerophospholipid metabolic processGO:0006650840.012
regulation of nucleotide biosynthetic processGO:0030808500.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of protein kinase activityGO:00458592890.012
Human
transforming growth factor beta receptor signaling pathwayGO:0007179760.012
negative regulation of response to external stimulusGO:0032102830.012
morphogenesis of an epitheliumGO:0002009600.012
organ formationGO:004864530.012
regulation of protein complex assemblyGO:00432541470.012
regulation of chondrocyte differentiationGO:003233090.012
nucleoside phosphate biosynthetic processGO:19012931090.012
regulation of camp biosynthetic processGO:0030817450.012
positive regulation of transferase activityGO:00513472270.012
establishment of nucleus localizationGO:004002310.012
proteoglycan metabolic processGO:0006029290.012
regulation of protein kinase b signalingGO:0051896610.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
cellular response to nitrogen compoundGO:19016991440.012
regulation of cellular component sizeGO:0032535820.012
semaphorin plexin signaling pathwayGO:007152640.012
positive regulation of mapk cascadeGO:00434101900.012
response to activityGO:001482300.012
sensory organ developmentGO:0007423520.011
anterior posterior axis specificationGO:000994820.011
positive regulation of proteolysisGO:00458621420.011
response to radiationGO:00093141510.011
response to inorganic substanceGO:00100351270.011
nucleoside monophosphate catabolic processGO:00091251590.011
ribonucleoprotein complex subunit organizationGO:0071826810.011
covalent chromatin modificationGO:00165692540.011
mitochondrion organizationGO:00070051560.011
g1 s transition of mitotic cell cycleGO:0000082780.011
respiratory gaseous exchangeGO:000758530.011
cell part morphogenesisGO:00329901370.011
cellular chemical homeostasisGO:00550821800.011
Yeast Mouse
regulation of phosphatase activityGO:0010921810.011
neuron deathGO:0070997650.011
transforming growth factor beta activationGO:003636310.011
protein kinase b signalingGO:0043491690.011
cardiac muscle tissue developmentGO:0048738390.011
negative regulation of phosphatase activityGO:0010923610.011
circulatory system processGO:00030131130.011
spermatid differentiationGO:004851540.011
prostate gland developmentGO:003085030.011
viral processGO:00160321460.011
establishment of protein localization to plasma membraneGO:0090002680.011
lipid localizationGO:00108761060.011
regulation of neuron deathGO:1901214560.011
mitotic nuclear divisionGO:00070671190.011
Yeast
regulation of microtubule based processGO:0032886740.011
hormone secretionGO:0046879650.011
striated muscle cell developmentGO:0055002270.011
negative regulation of cellular catabolic processGO:0031330830.011
myoblast fusionGO:000752010.010
sulfur compound metabolic processGO:00067901010.010
axon extension involved in axon guidanceGO:004884650.010
epithelial cell proliferationGO:00506731280.010
skeletal muscle organ developmentGO:0060538260.010
cyclic purine nucleotide metabolic processGO:0052652600.010
regulation of protein bindingGO:0043393660.010
sensory perceptionGO:00076001030.010
melanin metabolic processGO:000658210.010
regulation of receptor mediated endocytosisGO:0048259320.010
negative regulation of transferase activityGO:00513481240.010
Human
cell matrix adhesionGO:0007160850.010
regulation of growthGO:00400081650.010
jnk cascadeGO:0007254800.010

DMPK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.101
muscular diseaseDOID:00800001140.101
muscle tissue diseaseDOID:661130.030
myopathyDOID:4231040.030
nervous system diseaseDOID:8634310.015
central nervous system diseaseDOID:3311860.015
disease of metabolismDOID:00146672950.013
muscular dystrophyDOID:9884510.005
myotonic diseaseDOID:45030.000