Homo sapiens

81 known processes

ISG15

ISG15 ubiquitin-like modifier

(Aliases: IFI15,G1P2,IP17,UCRP,hUCRP)

ISG15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of viral genome replicationGO:0045069480.999
viral life cycleGO:00190581320.998
negative regulation of viral processGO:0048525660.989
symbiosis encompassing mutualism through parasitismGO:00444031560.985
defense response to virusGO:0051607710.982
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.972
defense response to other organismGO:00985421290.972
response to other organismGO:00517072610.953
negative regulation of viral genome replicationGO:0045071350.938
multi organism cellular processGO:00447641560.929
negative regulation of multi organism processGO:0043901920.916
response to biotic stimulusGO:00096072760.914
cellular response to cytokine stimulusGO:00713451810.838
regulation of defense response to virusGO:0050688330.811
immune effector processGO:00022521590.796
intracellular transport of viral protein in host cellGO:001906040.731
interspecies interaction between organismsGO:00444191560.677
response to external biotic stimulusGO:00432072610.627
lipoprotein biosynthetic processGO:0042158330.622
response to interferon alphaGO:0035455110.609
defense responseGO:00069523150.597
nucleoside phosphate biosynthetic processGO:19012931090.587
viral genome replicationGO:0019079500.555
interaction with hostGO:0051701420.529
response to cytokineGO:00340972320.524
regulation of viral processGO:00507921030.523
chemical homeostasisGO:00488783060.481
response to virusGO:00096151260.454
positive regulation of cell deathGO:00109422630.453
viral processGO:00160321460.433
cellular response to organic cyclic compoundGO:00714071270.425
intracellular protein transport in other organism involved in symbiotic interactionGO:005170840.374
negative regulation of defense response to virus by hostGO:005068940.370
cellular response to dsrnaGO:0071359190.366
protein lipidationGO:0006497330.365
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.345
negative regulation of cell deathGO:00605483450.341
cellular response to type i interferonGO:0071357120.320
negative regulation of catalytic activityGO:00430863350.310
response to organic cyclic compoundGO:00140702040.287
negative regulation of apoptotic processGO:00430663160.275
regulation of multi organism processGO:00439001570.271
regulation of intracellular transportGO:00323861950.249
protein myristoylationGO:001837710.214
intracellular protein transportGO:00068862700.213
response to dsrnaGO:0043331250.209
regulation by virus of viral protein levels in host cellGO:004671940.207
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.196
negative regulation of programmed cell deathGO:00430693210.166
positive regulation of apoptotic processGO:00430652460.163
regulation of intracellular protein transportGO:00331571230.161
nuclear transportGO:00511691790.152
extracellular transportGO:000685840.146
positive regulation of programmed cell deathGO:00430682490.143
negative regulation of immune effector processGO:0002698380.143
response to type i interferonGO:0034340140.136
regulation of apoptotic signaling pathwayGO:20012331750.126
regulation of defense response to virus by hostGO:0050691220.126
regulation of immune effector processGO:0002697910.126
nucleocytoplasmic transportGO:00069131760.125
negative regulation of apoptotic signaling pathwayGO:2001234970.123
regulation of nucleocytoplasmic transportGO:0046822980.110
glucose metabolic processGO:0006006450.107
negative regulation of cell motilityGO:20001461040.107
innate immune responseGO:00450871780.107
cellular response to interferon alphaGO:003545740.106
negative regulation of defense responseGO:0031348470.095
positive regulation of rig i signaling pathwayGO:190024640.093
multi organism localizationGO:1902579140.091
negative regulation of response to external stimulusGO:0032102830.088
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.084
regulation of cell migrationGO:00303342890.083
regulation of response to biotic stimulusGO:0002831550.081
symbiont intracellular protein transport in hostGO:003058140.080
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.078
interferon beta productionGO:0032608230.077
posttranscriptional gene silencingGO:0016441250.072
mapk cascadeGO:00001652880.071
positive regulation of proteolysisGO:00458621420.070
regulation of bindingGO:00510981110.069
negative regulation of hydrolase activityGO:00513461820.068
nucleoside phosphate catabolic processGO:19012924120.068
immune responseGO:00069553070.068
glycosylationGO:0070085710.065
regulation of protein localization to nucleusGO:1900180850.065
cytoplasmic transportGO:00164823790.065
positive regulation of interferon beta productionGO:0032728170.062
nucleic acid phosphodiester bond hydrolysisGO:00903051020.062
regulation of defense responseGO:00313471540.061
cellular macromolecular complex assemblyGO:00346223240.060
lipoprotein metabolic processGO:0042157420.059
epinephrine secretionGO:004824210.057
intracellular receptor signaling pathwayGO:00305221040.055
negative regulation of defense response to virusGO:0050687100.055
response to nitrogen compoundGO:19016981840.055
cellular macromolecule catabolic processGO:00442653800.053
Mouse
negative regulation of multicellular organismal processGO:00512413170.050
regulation of cell motilityGO:20001452990.048
regulation of protein bindingGO:0043393660.047
negative regulation of locomotionGO:00400131180.045
intracellular transport of virusGO:0075733140.045
ion homeostasisGO:00508012300.044
regulation of membrane potentialGO:0042391950.044
regulation of anatomical structure morphogenesisGO:00226032860.043
positive regulation of multi organism processGO:0043902560.043
regulation of cellular component movementGO:00512703340.041
interferon alpha productionGO:0032607110.041
cellular response to exogenous dsrnaGO:007136050.041
multi organism transportGO:0044766140.041
single organism cellular localizationGO:19025803320.040
protein localization to organelleGO:00333652800.037
negative regulation of cell migrationGO:00303361020.037
rna interferenceGO:001624640.037
release of cytochrome c from mitochondriaGO:0001836350.037
protein glycosylationGO:0006486620.036
modification dependent protein catabolic processGO:00199412090.036
Mouse
negative regulation of cellular component movementGO:00512711060.036
negative regulation of mitochondrial depolarizationGO:005190220.036
regulation of response to external stimulusGO:00321012220.034
rig i signaling pathwayGO:003952970.033
negative regulation of endopeptidase activityGO:0010951840.033
organophosphate biosynthetic processGO:00904071630.032
carbohydrate derivative biosynthetic processGO:19011372070.032
negative regulation of protein metabolic processGO:00512483910.032
cytidine metabolic processGO:004608770.031
response to exogenous dsrnaGO:0043330100.031
regulation of peptidase activityGO:00525471800.030
protein acylationGO:00435431380.030
positive regulation of intracellular protein transportGO:0090316760.030
protein export from nucleusGO:0006611290.030
mrna metabolic processGO:00160711750.029
ncrna metabolic processGO:00346601080.028
negative regulation of protein bindingGO:0032091350.028
negative regulation of immune system processGO:00026831360.028
regulation of body fluid levelsGO:0050878990.028
positive regulation of developmental processGO:00510943140.028
Mouse
positive regulation of cellular catabolic processGO:00313312840.027
regulation of nuclease activityGO:0032069110.027
regulation of cytoskeleton organizationGO:00514931770.027
mitochondrion organizationGO:00070051560.027
regulation of protein transportGO:00512232130.027
purine nucleotide biosynthetic processGO:0006164840.027
single organism nuclear importGO:19025931040.027
transport of virusGO:0046794140.026
response to abiotic stimulusGO:00096283360.026
protein catabolic processGO:00301633250.025
Mouse
chromatin organizationGO:00063253510.025
gene silencing by mirnaGO:0035195230.025
regulation of protein catabolic processGO:00421761550.024
response to interferon betaGO:0035456110.024
positive regulation of transferase activityGO:00513472270.023
nuclear exportGO:0051168690.023
negative regulation of cell proliferationGO:00082852280.023
determination of adult lifespanGO:000834020.022
negative regulation of kinase activityGO:00336731060.022
negative regulation of transferase activityGO:00513481240.022
posttranscriptional regulation of gene expressionGO:00106082130.022
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.022
positive regulation of hydrolase activityGO:00513453310.022
response to phenylpropanoidGO:008018410.021
organonitrogen compound biosynthetic processGO:19015662000.021
organophosphate catabolic processGO:00464344300.021
regulation of transferase activityGO:00513383550.020
regulation of ion homeostasisGO:2000021730.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
Mouse
regulation of cytoplasmic transportGO:19036491490.019
regulation of locomotionGO:00400123290.019
positive regulation of interleukin 4 productionGO:003275330.019
production of sirna involved in rna interferenceGO:003042230.019
atp metabolic processGO:00460341760.019
regulation of cell growthGO:00015581350.019
regulation of protein maturationGO:19033171500.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.018
negative regulation of phosphate metabolic processGO:00459362670.018
positive regulation of intracellular transportGO:00323881040.018
nucleoside triphosphate catabolic processGO:00091433940.017
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.017
cilium organizationGO:0044782680.017
dna damage response signal transduction resulting in transcriptionGO:0042772120.017
negative regulation of protein maturationGO:19033181420.017
ribonucleoside catabolic processGO:00424544060.017
ras protein signal transductionGO:0007265730.016
negative regulation of response to biotic stimulusGO:0002832180.016
response to steroid hormoneGO:0048545800.016
negative regulation of bindingGO:0051100570.016
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.016
regulation of rig i signaling pathwayGO:003953560.016
protein importGO:00170381300.016
positive regulation of viral processGO:0048524370.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
rna catabolic processGO:0006401710.015
cytokine productionGO:00018162470.015
dna catabolic processGO:0006308490.015
negative regulation of phosphorylationGO:00423261740.015
cellular protein catabolic processGO:00442572610.015
Mouse
epinephrine transportGO:004824110.015
nucleoside triphosphate metabolic processGO:00091414220.015
regulation of protein kinase activityGO:00458592890.015
negative regulation of protein processingGO:00109551420.015
rna phosphodiester bond hydrolysisGO:0090501350.014
negative regulation of proteolysisGO:00458611320.014
regulation of kinase activityGO:00435493140.014
cell fate determinationGO:000170930.014
regulation of helicase activityGO:005109580.014
positive regulation of interferon alpha productionGO:0032727110.014
nitrogen compound transportGO:00717051910.014
isg15 protein conjugationGO:003202050.014
protein targeting to nucleusGO:00447441040.014
embryo developmentGO:00097901230.013
protein modification by small protein conjugationGO:00324463420.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
atp catabolic processGO:00062001570.013
regulation of cellular response to stressGO:00801352440.013
regulation of growthGO:00400081650.013
protein maturationGO:00516042330.013
cellular response to transforming growth factor beta stimulusGO:0071560940.013
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.013
brain morphogenesisGO:004885410.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
cellular response to glucocorticoid stimulusGO:007138540.013
activation of cysteine type endopeptidase activityGO:0097202570.013
ossificationGO:00015031210.013
negative regulation of transportGO:00510511760.013
negative regulation of intracellular signal transductionGO:19025321830.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
cellular component morphogenesisGO:00329893140.013
regulation of endopeptidase activityGO:00525481700.012
purine ribonucleotide catabolic processGO:00091544040.012
regulation of interferon beta productionGO:0032648220.012
regulation of protein export from nucleusGO:0046825150.012
negative regulation of protein modification processGO:00314002000.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
regulation of protein serine threonine kinase activityGO:00719001790.012
negative regulation of catabolic processGO:00098951040.012
negative regulation of protein transportGO:0051224750.012
response to light stimulusGO:0009416870.012
positive regulation of endopeptidase activityGO:0010950840.012
positive regulation of peptidase activityGO:0010952880.012
purine containing compound catabolic processGO:00725234110.012
nucleotide catabolic processGO:00091664080.012
response to transforming growth factor betaGO:0071559940.012
ribonucleoside triphosphate catabolic processGO:00092033910.012
maintenance of locationGO:00512351120.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
rna processingGO:00063962550.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
glycerolipid metabolic processGO:00464861070.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
cellular response to nitrogen compoundGO:19016991440.011
nucleoside catabolic processGO:00091644080.011
response to growth factorGO:00708482050.011
regulation of protein stabilityGO:0031647870.011
positive regulation of cytokine productionGO:00018191670.011
modification dependent macromolecule catabolic processGO:00436322120.011
Mouse
negative regulation of interferon beta productionGO:003268840.011
signal transduction in absence of ligandGO:0038034220.011
positive regulation of interleukin 13 productionGO:003273640.011
cytokine mediated signaling pathwayGO:00192211090.010
negative regulation of developmental processGO:00510932470.010
nuclear importGO:00511701060.010
negative regulation of phosphorus metabolic processGO:00105632670.010
cardiovascular system developmentGO:00723582620.010

ISG15 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.078
aicardi goutieres syndromeDOID:005062970.058
connective tissue diseaseDOID:651090.036
bone diseaseDOID:0080001880.023
carbohydrate metabolism diseaseDOID:0050013320.019
glucose metabolism diseaseDOID:4194320.019
acquired metabolic diseaseDOID:0060158580.019
disease of metabolismDOID:00146672950.019
diabetes mellitusDOID:9351310.019
bone development diseaseDOID:0080006550.019
disease of cellular proliferationDOID:145661740.017
inherited metabolic disorderDOID:6552420.013
mitochondrial metabolism diseaseDOID:700290.013
cardiovascular system diseaseDOID:12871060.012