Homo sapiens

27 known processes

PLP1

proteolipid protein 1

(Aliases: MMPL,PLP,SPG2,PMD,PLP/DM20,HLD1)

PLP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nervous system developmentGO:00073992930.224
system processGO:00030083490.207
Zebrafish Rat
neurological system processGO:00508771630.190
Zebrafish Rat
regulation of cellular component movementGO:00512703340.177
generation of neuronsGO:00486991520.144
Human
regulation of cell differentiationGO:00455953930.135
multicellular organismal signalingGO:0035637340.127
Zebrafish Rat
central nervous system developmentGO:00074171230.121
membrane organizationGO:00610242920.119
positive regulation of cellular amine metabolic processGO:003324070.118
regulation of locomotionGO:00400123290.116
regulation of cellular amino acid metabolic processGO:000652160.112
cell developmentGO:00484683280.110
cellular amino acid metabolic processGO:00065201160.110
action potentialGO:0001508340.109
Zebrafish Rat
cell adhesionGO:00071553250.108
amine metabolic processGO:0009308440.106
regulation of cellular amine metabolic processGO:0033238110.105
neuronal action potentialGO:001922890.103
Zebrafish Rat
cellular component morphogenesisGO:00329893140.102
regulation of cell developmentGO:00602841610.100
transmission of nerve impulseGO:0019226110.098
Zebrafish Rat
positive regulation of developmental processGO:00510943140.098
positive regulation of cellular amino acid metabolic processGO:004576430.095
regulation of membrane potentialGO:0042391950.093
Zebrafish Rat
regulation of cellular ketone metabolic processGO:0010565500.090
regulation of anatomical structure morphogenesisGO:00226032860.085
biological adhesionGO:00226103310.085
ion transmembrane transportGO:00342203380.082
cellular amine metabolic processGO:0044106410.080
regulation of cell motilityGO:20001452990.080
nucleoside phosphate catabolic processGO:19012924120.080
chemical homeostasisGO:00488783060.078
enzyme linked receptor protein signaling pathwayGO:00071673030.077
purine nucleotide catabolic processGO:00061954050.076
neuron differentiationGO:00301821380.076
cellular ketone metabolic processGO:0042180800.074
purine ribonucleoside metabolic processGO:00461284370.074
positive regulation of cellular component organizationGO:00511303760.074
positive regulation of cell differentiationGO:00455972110.074
cell morphogenesisGO:00009022960.074
post embryonic developmentGO:000979120.073
ribonucleoside triphosphate catabolic processGO:00092033910.072
response to abiotic stimulusGO:00096283360.072
locomotory behaviorGO:000762610.071
positive regulation of cell migrationGO:00303351720.071
metal ion transportGO:00300012720.071
head developmentGO:00603221080.070
negative regulation of cell proliferationGO:00082852280.070
cell projection organizationGO:00300302520.070
positive regulation of locomotionGO:00400171860.069
small gtpase mediated signal transductionGO:0007264780.068
purine ribonucleoside catabolic processGO:00461303980.068
negative regulation of multicellular organismal processGO:00512413170.067
cardiovascular system developmentGO:00723582620.065
purine containing compound catabolic processGO:00725234110.065
glycosyl compound catabolic processGO:19016584130.065
positive regulation of synaptic transmissionGO:005080640.065
signal transduction by phosphorylationGO:00230142970.065
negative regulation of protein metabolic processGO:00512483910.064
transmembrane transportGO:00550853990.064
positive regulation of protein phosphorylationGO:00019343130.064
nucleoside triphosphate metabolic processGO:00091414220.063
purine ribonucleoside triphosphate catabolic processGO:00092073910.062
purine nucleoside triphosphate catabolic processGO:00091463920.062
actin filament based processGO:00300292240.062
positive regulation of phosphorylationGO:00423273940.062
ras protein signal transductionGO:0007265730.061
nucleotide catabolic processGO:00091664080.061
brain developmentGO:0007420970.061
nucleoside catabolic processGO:00091644080.061
cation transportGO:00068123310.059
ribonucleotide catabolic processGO:00092614050.058
regulation of cell migrationGO:00303342890.058
response to oxygen containing compoundGO:19017003690.058
purine ribonucleoside triphosphate metabolic processGO:00092054110.058
motor neuron axon guidanceGO:000804520.057
positive regulation of transportGO:00510503360.057
associative learningGO:000830610.056
nucleoside triphosphate catabolic processGO:00091433940.056
purine nucleoside catabolic processGO:00061523980.056
neuromuscular junction developmentGO:000752830.056
neurogenesisGO:00220081690.056
Human Rat
purine nucleoside triphosphate metabolic processGO:00091444120.055
ribonucleoside catabolic processGO:00424544060.054
cytoplasmic transportGO:00164823790.053
secretionGO:00469032540.053
regulation of nucleotide metabolic processGO:00061402690.053
blood vessel morphogenesisGO:00485141620.052
blood vessel developmentGO:00015681720.051
positive regulation of hydrolase activityGO:00513453310.051
anatomical structure formation involved in morphogenesisGO:00486462840.050
regulation of ion transportGO:00432691890.050
positive regulation of cell motilityGO:20001471770.050
rho protein signal transductionGO:0007266260.049
regulation of transferase activityGO:00513383550.049
regulation of kinase activityGO:00435493140.048
regulation of purine nucleotide metabolic processGO:19005422640.048
spinal cord developmentGO:002151040.048
regulation of synaptic plasticityGO:004816730.047
neuron projection developmentGO:00311751060.047
chemotaxisGO:00069351570.046
purine ribonucleotide catabolic processGO:00091544040.046
neuron fate commitmentGO:004866320.046
positive regulation of transferase activityGO:00513472270.046
negative regulation of cellular protein metabolic processGO:00322693530.046
regulation of mapk cascadeGO:00434082620.045
circulatory system developmentGO:00723592620.045
negative regulation of cell deathGO:00605483450.045
g protein coupled receptor signaling pathwayGO:00071862070.045
regulation of protein kinase activityGO:00458592890.045
regulation of hormone levelsGO:00108171250.045
startle responseGO:000196430.044
positive regulation of catabolic processGO:00098963100.044
nitrogen compound transportGO:00717051910.044
neuron developmentGO:00486661130.043
cell morphogenesis involved in differentiationGO:00009041440.043
positive regulation of cell proliferationGO:00082843010.043
secretion by cellGO:00329402260.043
positive regulation of nucleotide metabolic processGO:00459812300.043
ribonucleoside triphosphate metabolic processGO:00091994120.043
regulation of cell morphogenesisGO:00226041530.043
single organism membrane organizationGO:00448022680.042
mapk cascadeGO:00001652880.042
positive regulation of nucleotide catabolic processGO:00308131850.042
response to woundingGO:00096111680.041
regulation of secretion by cellGO:19035301770.041
actin cytoskeleton organizationGO:00300362070.040
regenerationGO:003109940.040
cell cell signalingGO:00072671550.040
segmentationGO:003528240.040
neurotransmitter secretionGO:000726940.040
regulation of epithelial cell migrationGO:0010632930.039
neuroblast proliferationGO:000740540.039
angiogenesisGO:00015251470.039
cellular response to oxygen containing compoundGO:19017012760.038
tissue migrationGO:00901301190.038
positive regulation of purine nucleotide metabolic processGO:19005442270.038
hindbrain developmentGO:003090230.038
gtp catabolic processGO:00061842370.038
inorganic cation transmembrane transportGO:00986621940.037
multicellular organismal agingGO:001025930.037
epithelium developmentGO:00604292270.037
epithelial cell migrationGO:00106311190.037
limbic system developmentGO:002176130.036
guanosine containing compound metabolic processGO:19010682440.036
positive regulation of purine nucleotide catabolic processGO:00331231850.036
regulation of cell morphogenesis involved in differentiationGO:0010769830.036
memoryGO:000761330.036
single organism cell adhesionGO:00986021790.036
organophosphate catabolic processGO:00464344300.036
response to organic cyclic compoundGO:00140702040.036
single organism cellular localizationGO:19025803320.036
regulation of cell projection organizationGO:00313441070.036
regulation of gtp catabolic processGO:00331241800.035
positive regulation of cellular catabolic processGO:00313312840.035
positive regulation of nucleoside metabolic processGO:00459791860.035
lipid metabolic processGO:00066293810.035
negative regulation of phosphate metabolic processGO:00459362670.035
organic anion transportGO:00157111030.035
negative regulation of catalytic activityGO:00430863350.035
female gamete generationGO:000729220.035
gtp metabolic processGO:00460392390.034
regulation of nervous system developmentGO:0051960880.034
cation transmembrane transportGO:00986552380.034
negative regulation of apoptotic processGO:00430663160.034
vasculature developmentGO:00019441810.034
regulation of nucleoside metabolic processGO:00091182090.034
determination of adult lifespanGO:000834020.034
epithelium migrationGO:00901321190.034
intracellular protein transportGO:00068862700.033
regulation of protein serine threonine kinase activityGO:00719001790.033
regulation of protein localizationGO:00328802960.033
peptidyl tyrosine phosphorylationGO:00181081700.033
behaviorGO:00076101120.033
regulation of secretionGO:00510461940.033
cell fate determinationGO:000170930.033
regulation of cell growthGO:00015581350.033
adult locomotory behaviorGO:000834410.032
regulation of cellular component biogenesisGO:00440872810.032
anion transportGO:00068201610.032
postsynaptic membrane organizationGO:000194120.032
cellular chemical homeostasisGO:00550821800.032
endothelial cell migrationGO:0043542860.032
positive regulation of kinase activityGO:00336742040.031
positive regulation of cellular component movementGO:00512721810.031
cellular metal ion homeostasisGO:00068751460.031
growthGO:00400072020.031
positive regulation of cell deathGO:00109422630.031
vesicle mediated transportGO:00161923710.031
guanosine containing compound catabolic processGO:19010692390.031
positive regulation of protein kinase activityGO:00458601900.031
muscle contractionGO:0006936730.031
negative regulation of phosphorus metabolic processGO:00105632670.031
cell growthGO:00160491600.030
regulation of cell adhesionGO:00301551660.030
peripheral nervous system developmentGO:000742220.030
regulation of neurogenesisGO:0050767820.030
positive regulation of gtpase activityGO:00435471660.030
actin filament based movementGO:0030048170.030
regulation of gtpase activityGO:00430871800.030
taxisGO:00423301570.030
endomembrane system organizationGO:00102561960.030
negative regulation of cellular component organizationGO:00511292350.030
cell part morphogenesisGO:00329901370.030
muscle system processGO:0003012810.029
inorganic ion transmembrane transportGO:00986602310.029
cellular response to growth factor stimulusGO:00713631970.029
negative regulation of gliogenesisGO:001401430.029
peptidyl tyrosine modificationGO:00182121700.029
defense responseGO:00069523150.028
regulation of establishment of protein localizationGO:00702012420.028
negative regulation of developmental processGO:00510932470.028
ameboidal type cell migrationGO:00016671350.028
regulation of purine nucleotide catabolic processGO:00331212050.028
organonitrogen compound biosynthetic processGO:19015662000.028
cellular ion homeostasisGO:00068731680.028
regulation of behaviorGO:0050795820.027
positive regulation of mapk cascadeGO:00434101900.027
oogenesisGO:004847720.027
cellular macromolecular complex assemblyGO:00346223240.027
regulation of small gtpase mediated signal transductionGO:00510561560.027
positive regulation of cell developmentGO:0010720920.027
regulation of excitatory postsynaptic membrane potentialGO:006007910.027
cellular lipid metabolic processGO:00442553030.027
regulation of actin filament based processGO:00329701410.027
response to lipidGO:00339932060.027
regulation of angiogenesisGO:0045765920.027
astrocyte differentiationGO:004870840.027
regulation of intracellular transportGO:00323861950.026
positive regulation of immune system processGO:00026842830.026
regulation of response to external stimulusGO:00321012220.026
positive regulation of gtp catabolic processGO:00331261660.026
negative regulation of cell motilityGO:20001461040.026
morphogenesis of a polarized epitheliumGO:000173830.026
positive regulation of ras gtpase activityGO:00323201170.026
regulation of proteolysisGO:00301622930.026
rhythmic behaviorGO:000762220.026
negative regulation of programmed cell deathGO:00430693210.026
presynaptic membrane organizationGO:009709030.026
metencephalon developmentGO:002203720.025
regulation of neuron projection developmentGO:0010975570.025
cellular response to organic cyclic compoundGO:00714071270.025
somatic stem cell maintenanceGO:003501940.025
neuron projection regenerationGO:003110210.025
regulation of growthGO:00400081650.025
apoptotic signaling pathwayGO:00971902680.025
regulation of axon guidanceGO:190266730.025
response to hormoneGO:00097251750.024
regulation of cell cycleGO:00517263930.024
regulation of neural precursor cell proliferationGO:200017740.024
regulation of neurotransmitter secretionGO:004692830.024
negative regulation of protein modification processGO:00314002000.024
dephosphorylationGO:00163112090.024
cellular macromolecule catabolic processGO:00442653800.024
response to external biotic stimulusGO:00432072610.024
protein catabolic processGO:00301633250.024
canonical wnt signaling pathwayGO:00600701160.023
cardiac muscle cell contractionGO:008600340.023
regulation of neuron differentiationGO:0045664700.023
circadian behaviorGO:004851220.023
negative regulation of phosphorylationGO:00423261740.023
cell projection morphogenesisGO:00488581290.023
maintenance of locationGO:00512351120.023
regulation of canonical wnt signaling pathwayGO:0060828880.023
somatic stem cell divisionGO:004810310.023
positive regulation of apoptotic processGO:00430652460.023
morphogenesis of embryonic epitheliumGO:001633140.023
regulation of cytoskeleton organizationGO:00514931770.023
mitotic cell cycleGO:00002783260.023
negative regulation of locomotionGO:00400131180.023
synaptic transmissionGO:0007268610.023
cellular response to cytokine stimulusGO:00713451810.023
regulation of cell cycle processGO:00105642660.023
cellular homeostasisGO:00197251960.023
cerebellum developmentGO:002154920.023
cellular cation homeostasisGO:00300031630.023
regulation of nucleotide catabolic processGO:00308112050.022
metal ion homeostasisGO:00550651690.022
positive regulation of gliogenesisGO:001401540.022
cellular response to endogenous stimulusGO:00714953360.022
divalent inorganic cation homeostasisGO:00725071360.022
regulation of protein transportGO:00512232130.022
regulation of ion transmembrane transportGO:00347651320.022
positive regulation of nervous system developmentGO:0051962540.022
single organismal cell cell adhesionGO:00163371480.022
regulation of wnt signaling pathwayGO:00301111230.022
presynaptic membrane assemblyGO:009710510.022
wnt signaling pathwayGO:00160551560.022
organ morphogenesisGO:00098871470.022
stem cell divisionGO:001714520.022
regulation of actin cytoskeleton organizationGO:00329561160.022
regulation of anatomical structure sizeGO:00900661010.022
response to other organismGO:00517072610.022
regulation of transmission of nerve impulseGO:005196920.022
blastoderm segmentationGO:000735020.022
sequestering of metal ionGO:0051238240.022
negative regulation of cell differentiationGO:00455961710.021
forebrain neuron differentiationGO:002187930.021
regulation of ras protein signal transductionGO:00465781550.021
positive regulation of organelle organizationGO:00106381950.021
cellular response to nitrogen compoundGO:19016991440.021
protein maturationGO:00516042330.021
positive regulation of cellular component biogenesisGO:00440891580.021
response to cytokineGO:00340972320.021
nucleoside monophosphate metabolic processGO:00091231910.021
response to axon injuryGO:004867810.021
reactive oxygen species metabolic processGO:0072593750.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
protein localization to organelleGO:00333652800.021
midbrain developmentGO:0030901450.021
cellular response to dna damage stimulusGO:00069743790.021
asymmetric neuroblast divisionGO:005505910.021
protein ubiquitinationGO:00165673140.021
neural nucleus developmentGO:0048857470.021
atp metabolic processGO:00460341760.020
regulation of immune responseGO:00507762010.020
monocarboxylic acid metabolic processGO:00327871850.020
response to nitrogen compoundGO:19016981840.020
neural crest cell developmentGO:001403230.020
response to growth factorGO:00708482050.020
ribonucleoside monophosphate metabolic processGO:00091611870.020
protein targetingGO:00066051870.020
photoreceptor cell differentiationGO:004653020.020
ion homeostasisGO:00508012300.020
regulation of intracellular protein transportGO:00331571230.020
mitotic cell cycle processGO:19030472860.020
blood circulationGO:00080151130.020
somitogenesisGO:000175620.020
immune responseGO:00069553070.020
response to auditory stimulusGO:001099640.020
negative regulation of hydrolase activityGO:00513461820.020
calcium ion transportGO:00068161470.020
divalent inorganic cation transportGO:00725111580.020
protein processingGO:00164852260.020
regulation of ras gtpase activityGO:00323181280.019
carbohydrate derivative biosynthetic processGO:19011372070.019
lipid biosynthetic processGO:00086101770.019
protein localization to membraneGO:00726571600.019
establishment of protein localization to organelleGO:00725941720.019
protein modification by small protein conjugationGO:00324463420.019
actin mediated cell contractionGO:0070252120.019
cell divisionGO:00513011680.019
hormone transportGO:0009914680.019
substantia nigra developmentGO:0021762450.019
regulation of glial cell differentiationGO:004568530.019
forebrain generation of neuronsGO:002187230.019
protein autophosphorylationGO:00467771230.019
hippocampus developmentGO:002176610.019
glial cell migrationGO:000834740.019
regulation of cellular response to stressGO:00801352440.019
divalent metal ion transportGO:00708381520.019
positive regulation of neurogenesisGO:0050769490.019
regulation of epithelial cell proliferationGO:00506781130.018
nucleocytoplasmic transportGO:00069131760.018
asymmetric stem cell divisionGO:009872210.018
negative regulation of transportGO:00510511760.018
activation of protein kinase activityGO:0032147900.018
negative regulation of cell migrationGO:00303361020.018
spermatid differentiationGO:004851540.018
pituitary gland developmentGO:002198320.018
positive regulation of neuron differentiationGO:0045666400.018
cell substrate adhesionGO:00315891320.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
embryonic epithelial tube formationGO:000183840.018
regulation of vasculature developmentGO:1901342970.018
anterior posterior axis specificationGO:000994820.018
cell type specific apoptotic processGO:00972851250.018
negative regulation of cell cycleGO:00457861930.017
nuclear transportGO:00511691790.017
regulation of cytokine productionGO:00018172320.017
cellular protein catabolic processGO:00442572610.017
regulation of response to woundingGO:19030341010.017
regulation of protein maturationGO:19033171500.017
response to inorganic substanceGO:00100351270.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
peptide hormone secretionGO:0030072500.017
cellular protein complex assemblyGO:00436231880.017
organelle assemblyGO:00709251760.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.017
axis elongationGO:000340140.017
innate immune responseGO:00450871780.017
chromatin modificationGO:00165682980.017
sex determinationGO:000753030.017
regulation of cytoplasmic transportGO:19036491490.017
response to radiationGO:00093141510.017
ribonucleoside monophosphate catabolic processGO:00091581580.017
regulation of chemotaxisGO:0050920740.017
chromatin organizationGO:00063253510.017
carbohydrate metabolic processGO:00059752070.017
signal releaseGO:0023061700.017
positive regulation of cell projection organizationGO:0031346640.017
regulation of peptidyl tyrosine phosphorylationGO:00507301080.017
sequestering of calcium ionGO:0051208170.017
regulation of apoptotic signaling pathwayGO:20012331750.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
plasma membrane organizationGO:00070091150.016
microtubule based processGO:00070172100.016
forebrain developmentGO:0030900260.016
negative regulation of protein phosphorylationGO:00019331400.016
regulation of metal ion transportGO:00109591200.016
response to drugGO:0042493810.016
negative regulation of cellular component movementGO:00512711060.016
long term memoryGO:000761620.016
epithelial cell proliferationGO:00506731280.016
ossificationGO:00015031210.016
regulation of ion transmembrane transporter activityGO:0032412720.016
positive regulation of programmed cell deathGO:00430682490.016
visual learningGO:000854210.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
compound eye developmentGO:004874910.016
regulation of axon extension involved in axon guidanceGO:004884120.016
erk1 and erk2 cascadeGO:00703711040.016
brain morphogenesisGO:004885410.016
regulation of map kinase activityGO:00434051080.016
negative regulation of cellular amine metabolic processGO:003323930.016
spermatid developmentGO:000728640.016
striated muscle contractionGO:0006941520.016
digestive tract developmentGO:0048565750.016
cellular response to lipidGO:00713961270.016
atp catabolic processGO:00062001570.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
regulation of hormone secretionGO:0046883570.016
second messenger mediated signalingGO:0019932780.016
regulation of synaptic vesicle transportGO:190280330.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
cation homeostasisGO:00550801890.016
neuroblast divisionGO:005505710.015
positive regulation of neural precursor cell proliferationGO:200017920.015
single organism carbohydrate metabolic processGO:00447231930.015
nerve developmentGO:002167540.015
epithelial cell differentiationGO:00308551410.015
peptide transportGO:0015833740.015
stress activated mapk cascadeGO:0051403930.015
stem cell differentiationGO:0048863930.015
Human
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
regulation of protein processingGO:00706131500.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
negative regulation of protein processingGO:00109551420.015
negative regulation of secretionGO:0051048580.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
tissue morphogenesisGO:0048729960.015
establishment of planar polarityGO:000173630.015
neuron projection morphogenesisGO:0048812500.015
ventral spinal cord developmentGO:002151710.015
cell projection assemblyGO:00300311260.015
negative regulation of protein maturationGO:19033181420.015
regulation of stress activated protein kinase signaling cascadeGO:0070302850.015
stress activated protein kinase signaling cascadeGO:0031098940.015
regulation of mitotic cell cycleGO:00073461890.015
peptidyl serine phosphorylationGO:00181051010.015
midgut developmentGO:000749410.014
negative regulation of secretion by cellGO:1903531520.014
sensory perception of smellGO:000760820.014
modification dependent macromolecule catabolic processGO:00436322120.014
long term synaptic potentiationGO:006029110.014
anterior posterior axis specification embryoGO:000859520.014
endodermal cell fate commitmentGO:000171140.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
response to biotic stimulusGO:00096072760.014
amino acid transportGO:0006865280.014
cytokine productionGO:00018162470.014
axon regenerationGO:003110310.014
lens development in camera type eyeGO:000208820.014
neural tube formationGO:000184130.014
regulation of endothelial cell migrationGO:0010594670.014
immune system developmentGO:00025201950.014
carboxylic acid transportGO:0046942630.014
negative regulation of cell developmentGO:0010721480.014
protein oligomerizationGO:00512591730.014
regulation of dephosphorylationGO:0035303960.014
negative regulation of canonical wnt signaling pathwayGO:0090090550.014
myoblast fusionGO:000752010.014
interspecies interaction between organismsGO:00444191560.014
organ formationGO:004864530.014

PLP1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.046
nervous system diseaseDOID:8634310.046
sensory system diseaseDOID:00501552030.029
musculoskeletal system diseaseDOID:172230.027
eye diseaseDOID:56141490.027
eye and adnexa diseaseDOID:14921500.027
brain diseaseDOID:936730.023
cardiovascular system diseaseDOID:12871060.023
disease of metabolismDOID:00146672950.020
inherited metabolic disorderDOID:6552420.019
cancerDOID:1621670.016
disease of cellular proliferationDOID:145661740.016
retinal diseaseDOID:56791180.014
muscle tissue diseaseDOID:661130.014
myopathyDOID:4231040.014
muscular diseaseDOID:00800001140.014
organ system cancerDOID:00506861640.014
disease of mental healthDOID:150700.014