Homo sapiens

0 known processes

PKLR

pyruvate kinase, liver and RBC

(Aliases: PKR,PKRL,RPK,PK1,PKL)

PKLR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chemical homeostasisGO:00488783060.356
transmembrane transportGO:00550853990.303
anion transportGO:00068201610.280
regulation of body fluid levelsGO:0050878990.277
cellular lipid metabolic processGO:00442553030.249
response to oxygen containing compoundGO:19017003690.247
Rat
cellular amino acid metabolic processGO:00065201160.222
ion transmembrane transportGO:00342203380.222
monocarboxylic acid metabolic processGO:00327871850.186
Yeast Rat
coagulationGO:0050817780.173
cation transmembrane transportGO:00986552380.168
cellular amine metabolic processGO:0044106410.163
g protein coupled receptor signaling pathwayGO:00071862070.147
cellular response to endogenous stimulusGO:00714953360.143
Rat
organic anion transportGO:00157111030.131
lipid metabolic processGO:00066293810.128
cellular ketone metabolic processGO:0042180800.124
cation transportGO:00068123310.122
urate transportGO:001574730.118
hemostasisGO:0007599760.118
regulation of blood coagulationGO:0030193420.117
cellular chemical homeostasisGO:00550821800.114
ion homeostasisGO:00508012300.112
response to woundingGO:00096111680.103
metal ion homeostasisGO:00550651690.102
regulation of response to woundingGO:19030341010.099
cellular divalent inorganic cation homeostasisGO:00725031280.097
cation homeostasisGO:00550801890.092
response to biotic stimulusGO:00096072760.091
cellular homeostasisGO:00197251960.089
renal tubular secretionGO:009725410.088
oxidation reduction processGO:00551143960.086
regulation of hemostasisGO:1900046420.084
regulation of cellular amino acid metabolic processGO:000652160.084
amine metabolic processGO:0009308440.082
regulation of wound healingGO:0061041560.081
cellular cation homeostasisGO:00300031630.078
regulation of hormone levelsGO:00108171250.077
inorganic ion transmembrane transportGO:00986602310.074
regulation of response to external stimulusGO:00321012220.074
cellular response to oxygen containing compoundGO:19017012760.073
Rat
sulfur compound metabolic processGO:00067901010.072
wound healingGO:00420601150.071
regulation of cellular amine metabolic processGO:0033238110.069
blood coagulationGO:0007596760.068
cofactor metabolic processGO:0051186870.065
carboxylic acid biosynthetic processGO:0046394970.063
Rat
cytoplasmic transportGO:00164823790.062
protein processingGO:00164852260.062
regulation of ion transportGO:00432691890.061
organic hydroxy compound metabolic processGO:19016151470.061
organonitrogen compound biosynthetic processGO:19015662000.060
Rat
regulation of cellular ketone metabolic processGO:0010565500.058
metal ion transportGO:00300012720.057
immune responseGO:00069553070.056
response to external biotic stimulusGO:00432072610.056
phylloquinone metabolic processGO:004237420.054
inorganic cation transmembrane transportGO:00986621940.051
response to abiotic stimulusGO:00096283360.051
Rat
cellular metal ion homeostasisGO:00068751460.048
positive regulation of transportGO:00510503360.048
small molecule catabolic processGO:0044282920.047
memoryGO:000761330.046
anion transmembrane transportGO:0098656760.046
carbohydrate derivative biosynthetic processGO:19011372070.046
Rat
cellular ion homeostasisGO:00068731680.045
glycerolipid metabolic processGO:00464861070.045
monovalent inorganic cation transportGO:00156721280.044
negative regulation of protein metabolic processGO:00512483910.044
regulation of cytokine productionGO:00018172320.044
lipid transportGO:0006869900.044
immune effector processGO:00022521590.043
post embryonic developmentGO:000979120.043
system processGO:00030083490.042
lipid catabolic processGO:0016042840.042
lipid biosynthetic processGO:00086101770.042
divalent inorganic cation homeostasisGO:00725071360.041
positive regulation of cellular amine metabolic processGO:003324070.041
organic acid catabolic processGO:0016054710.041
alpha ketoglutarate transportGO:001574210.041
response to other organismGO:00517072610.040
small molecule biosynthetic processGO:00442831570.040
Rat
organic acid transportGO:0015849650.040
single organism carbohydrate metabolic processGO:00447231930.040
Yeast Rat
response to organic cyclic compoundGO:00140702040.039
Rat
steroid metabolic processGO:0008202940.039
response to nitrogen compoundGO:19016981840.039
Rat
response to hormoneGO:00097251750.038
Rat
response to organonitrogen compoundGO:00102431560.038
Rat
fatty acid metabolic processGO:00066311150.038
regulation of proteolysisGO:00301622930.038
carboxylic acid transportGO:0046942630.037
cytokine productionGO:00018162470.037
negative regulation of catalytic activityGO:00430863350.036
vitamin k catabolic processGO:004237720.036
positive regulation of cellular amino acid metabolic processGO:004576430.034
response to inorganic substanceGO:00100351270.034
Rat
regulation of killing of cells of other organismGO:005170940.033
nicotinate transportGO:200114210.032
determination of adult lifespanGO:000834020.032
positive regulation of phosphorylationGO:00423273940.032
negative regulation of protein processingGO:00109551420.032
alcohol metabolic processGO:00060661140.032
short chain fatty acid transportGO:001591210.032
carboxylic acid catabolic processGO:0046395710.032
positive regulation of intestinal epithelial structure maintenanceGO:006073110.031
multicellular organismal agingGO:001025930.031
organic acid biosynthetic processGO:0016053970.031
Rat
cellular calcium ion homeostasisGO:00068741170.030
calcium ion homeostasisGO:00550741220.030
positive regulation of ion transportGO:0043270870.030
coenzyme metabolic processGO:0006732650.030
protein maturationGO:00516042330.030
cellular lipid catabolic processGO:0044242650.029
monocarboxylic acid biosynthetic processGO:0072330670.029
Rat
cellular response to organonitrogen compoundGO:00714171240.029
Rat
vitamin k biosynthetic processGO:004237120.028
negative regulation of response to woundingGO:1903035470.028
response to radiationGO:00093141510.028
nitrogen compound transportGO:00717051910.028
intracellular protein transportGO:00068862700.028
leukocyte activationGO:00453211640.028
regulation of high density lipoprotein particle clearanceGO:001098220.027
negative regulation of icosanoid secretionGO:003230420.027
sodium independent organic anion transportGO:004325220.027
lipid localizationGO:00108761060.027
modification of morphology or physiology of other organismGO:0035821430.027
cell activationGO:00017752130.027
organic hydroxy compound transportGO:0015850630.026
locomotory behaviorGO:000762610.026
organophosphate biosynthetic processGO:00904071630.026
Rat
vesicle mediated transportGO:00161923710.026
leukotriene b4 metabolic processGO:003610220.026
response to purine containing compoundGO:0014074400.026
Rat
regenerationGO:003109940.026
negative regulation of transportGO:00510511760.026
negative regulation of immune effector processGO:0002698380.026
biological adhesionGO:00226103310.025
purine ribonucleoside metabolic processGO:00461284370.025
Rat
female gamete generationGO:000729220.025
carbohydrate metabolic processGO:00059752070.025
Yeast Rat
cellular response to hormone stimulusGO:00328701250.025
Rat
negative regulation of cellular protein metabolic processGO:00322693530.025
negative regulation of cell proliferationGO:00082852280.024
regulation of immune responseGO:00507762010.024
negative regulation of cell deathGO:00605483450.024
organophosphate catabolic processGO:00464344300.024
sodium dependent organic cation transportGO:007071510.024
regulation of membrane potentialGO:0042391950.024
divalent metal ion transportGO:00708381520.023
regulation of cell differentiationGO:00455953930.023
quinone catabolic processGO:190166220.023
nucleoside monophosphate metabolic processGO:00091231910.023
Rat
homeostasis of number of cells in a free living populationGO:004887410.023
regulation of cell activationGO:00508651250.023
single organism cellular localizationGO:19025803320.022
nucleoside phosphate biosynthetic processGO:19012931090.022
Rat
single organism membrane organizationGO:00448022680.022
negative regulation of multicellular organismal processGO:00512413170.022
purine containing compound catabolic processGO:00725234110.022
growthGO:00400072020.022
secretionGO:00469032540.021
short chain fatty acid importGO:001591310.021
pressure natriuresisGO:000309520.021
inorganic anion transportGO:0015698600.021
alpha amino acid metabolic processGO:1901605720.021
cellular amide metabolic processGO:0043603690.021
nucleotide catabolic processGO:00091664080.021
cellular response to cytokine stimulusGO:00713451810.021
urate metabolic processGO:0046415110.021
lipid modificationGO:0030258840.021
cellular potassium ion transportGO:0071804600.020
regulation of peptidase activityGO:00525471800.020
purine ribonucleoside monophosphate metabolic processGO:00091671860.020
Rat
response to virusGO:00096151260.020
cellular response to nitrogen compoundGO:19016991440.020
Rat
menaquinone catabolic processGO:004236120.020
maintenance of locationGO:00512351120.020
negative regulation of immune system processGO:00026831360.020
negative regulation of proteolysisGO:00458611320.019
membrane organizationGO:00610242920.019
potassium ion transportGO:0006813620.019
positive regulation of cytokine productionGO:00018191670.019
cellular response to organic cyclic compoundGO:00714071270.019
negative regulation of protein maturationGO:19033181420.019
regulation of lipid transportGO:0032368440.019
negative regulation of apoptotic processGO:00430663160.019
positive regulation of hydrolase activityGO:00513453310.019
divalent inorganic cation transportGO:00725111580.019
regulation of protein processingGO:00706131500.019
regulation of transmembrane transporter activityGO:0022898740.019
regulation of protein localizationGO:00328802960.019
positive regulation of cytosolic calcium ion concentrationGO:0007204820.019
response to drugGO:0042493810.019
epithelium developmentGO:00604292270.019
associative learningGO:000830610.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
inorganic anion transmembrane transportGO:0098661470.018
response to lipidGO:00339932060.018
vitamin e metabolic processGO:004236010.018
defense response to virusGO:0051607710.018
regulation of cell cycleGO:00517263930.018
behaviorGO:00076101120.018
reactive oxygen species metabolic processGO:0072593750.018
response to acid chemicalGO:0001101660.018
phylloquinone catabolic processGO:004237620.018
muscle contractionGO:0006936730.018
nucleoside phosphate catabolic processGO:19012924120.018
purine nucleoside monophosphate metabolic processGO:00091261860.018
Rat
oogenesisGO:004847720.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
Rat
response to organophosphorusGO:0046683410.017
Rat
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
purine nucleoside triphosphate metabolic processGO:00091444120.017
Rat
regulation of protein maturationGO:19033171500.017
protein oligomerizationGO:00512591730.017
lymphocyte activationGO:00466491330.017
regulation of t cell activationGO:0050863770.017
negative regulation of programmed cell deathGO:00430693210.017
response to disaccharideGO:003428510.017
posttranscriptional regulation of gene expressionGO:00106082130.017
nucleoside monophosphate catabolic processGO:00091251590.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
Rat
regulation of dna metabolic processGO:00510521530.017
fatty acid biosynthetic processGO:0006633460.017
negative regulation of endopeptidase activityGO:0010951840.017
nucleoside triphosphate metabolic processGO:00091414220.016
Rat
negative regulation of cellular amine metabolic processGO:003323930.016
secretion by cellGO:00329402260.016
calcium ion transportGO:00068161470.016
neurological system processGO:00508771630.016
atp metabolic processGO:00460341760.016
Rat
negative regulation of cellular component organizationGO:00511292350.016
cellular response to growth factor stimulusGO:00713631970.016
negative regulation of peptidase activityGO:0010466910.016
defense response to other organismGO:00985421290.016
positive regulation of plasminogen activationGO:001075630.016
alpha amino acid catabolic processGO:1901606260.016
regulation of cellular component movementGO:00512703340.016
regulation of ion transmembrane transporter activityGO:0032412720.016
glycerophospholipid metabolic processGO:0006650840.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
Rat
dephosphorylationGO:00163112090.016
cellular response to disaccharide stimulusGO:007132410.015
quorum sensingGO:000937210.015
cellular response to oxidative stressGO:0034599850.015
multi organism cellular processGO:00447641560.015
carnitine transmembrane transportGO:190260330.015
positive regulation of digestive system processGO:006045620.015
cardiovascular system developmentGO:00723582620.015
positive regulation of killing of cells of other organismGO:005171240.015
icosanoid catabolic processGO:190152320.015
sensory perception of painGO:001923340.015
response to cytokineGO:00340972320.015
negative regulation of hydrolase activityGO:00513461820.015
response to decreased oxygen levelsGO:0036293960.015
Rat
regulation of transporter activityGO:0032409820.015
sequestering of metal ionGO:0051238240.015
regulation of establishment of protein localizationGO:00702012420.015
establishment of protein localization to organelleGO:00725941720.015
phospholipid metabolic processGO:0006644990.015
positive regulation of organic acid transportGO:003289230.015
response to fungusGO:000962040.015
peripheral nervous system developmentGO:000742220.015
neutral lipid metabolic processGO:0006638270.015
sensory perceptionGO:00076001030.015
positive regulation of catabolic processGO:00098963100.015
tissue regenerationGO:004224630.015
regulation of intracellular transportGO:00323861950.015
negative regulation of cytosolic calcium ion concentrationGO:005148110.014
one carbon compound transportGO:001975540.014
regulation of mononuclear cell proliferationGO:0032944650.014
peptidyl tyrosine modificationGO:00182121700.014
regulation of cell migrationGO:00303342890.014
negative regulation of phosphorus metabolic processGO:00105632670.014
negative regulation of response to external stimulusGO:0032102830.014
fatty acid derivative catabolic processGO:190156920.014
leukotriene catabolic processGO:003610020.014
regulation of protein transportGO:00512232130.014
t cell activationGO:0042110990.014
response to nutrient levelsGO:0031667810.014
Rat
regulation of cell motilityGO:20001452990.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of leukocyte activationGO:00026941150.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
regulation of lymphocyte activationGO:00512491030.014
cellular response to abiotic stimulusGO:00712141170.014
cellular protein catabolic processGO:00442572610.014
epithelial cell differentiationGO:00308551410.014
regulation of epithelial cell migrationGO:0010632930.014
regulation of cell cycle processGO:00105642660.014
regulation of cytoplasmic transportGO:19036491490.014
regulation of homeostatic processGO:00328441210.014
mitotic cell cycleGO:00002783260.014
hormone metabolic processGO:0042445610.014
positive regulation of developmental processGO:00510943140.014
response to steroid hormoneGO:0048545800.014
visual behaviorGO:000763220.014
negative regulation of voltage gated calcium channel activityGO:190138640.014
purine nucleotide catabolic processGO:00061954050.014
modification dependent protein catabolic processGO:00199412090.014
multicellular organismal response to stressGO:003355510.014
sequestering of calcium ionGO:0051208170.014
positive regulation of monooxygenase activityGO:0032770140.013
positive regulation of cellular catabolic processGO:00313312840.013
l amino acid importGO:004309240.013
negative regulation of immune responseGO:0050777400.013
negative regulation of blood coagulationGO:0030195220.013
rhythmic behaviorGO:000762220.013
protein modification by small protein removalGO:0070646920.013
mitochondrion organizationGO:00070051560.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
negative regulation of protein modification processGO:00314002000.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
neuromuscular junction developmentGO:000752830.013
response to corticotropin releasing hormoneGO:004343510.013
cellular macromolecular complex assemblyGO:00346223240.013
positive regulation of cellular component movementGO:00512721810.013
nuclear transportGO:00511691790.013
defense responseGO:00069523150.013
nucleocytoplasmic transportGO:00069131760.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
endocytosisGO:00068971590.013
segmentationGO:003528240.013
positive regulation of multi organism processGO:0043902560.013
purine ribonucleotide biosynthetic processGO:0009152790.013
Rat
regulation of growthGO:00400081650.013
cell morphogenesisGO:00009022960.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
circadian behaviorGO:004851220.013
atp catabolic processGO:00062001570.013
glycoprotein metabolic processGO:00091001100.013
cellular response to glucagon stimulusGO:007137710.013
protein catabolic processGO:00301633250.013
protein localization to organelleGO:00333652800.013
nucleoside triphosphate catabolic processGO:00091433940.012
monosaccharide metabolic processGO:0005996740.012
regulation of leukocyte proliferationGO:0070663670.012
behavioral response to ethanolGO:004814920.012
response to insulinGO:0032868450.012
Rat
hematopoietic or lymphoid organ developmentGO:00485341860.012
cell adhesionGO:00071553250.012
epithelial cell proliferationGO:00506731280.012
peptidyl tyrosine phosphorylationGO:00181081700.012
regulation of synaptic plasticityGO:004816730.012
nucleoside catabolic processGO:00091644080.012
protein modification by small protein conjugationGO:00324463420.012
negative regulation of intracellular signal transductionGO:19025321830.012
cellular macromolecule catabolic processGO:00442653800.012
response to peptideGO:1901652650.012
Rat
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.012
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163510.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.012
menaquinone metabolic processGO:000923330.012
response to light stimulusGO:0009416870.012
thyroid hormone metabolic processGO:004240340.012
positive regulation of fatty acid transportGO:200019330.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
sensory perception of smellGO:000760820.012
cyclic nucleotide biosynthetic processGO:0009190610.012
matingGO:000761810.012
interspecies interaction between organismsGO:00444191560.012
hormone transportGO:0009914680.012
blastoderm segmentationGO:000735020.012
regulation of lymphocyte proliferationGO:0050670640.012
epithelial cell migrationGO:00106311190.012
acylglycerol metabolic processGO:0006639270.012
chloride transportGO:0006821410.012
positive regulation of cell migrationGO:00303351720.012
cellular response to peptideGO:1901653590.012
Rat
response to oxidative stressGO:00069791210.012
defense response to fungusGO:005083240.012
negative regulation of hemostasisGO:1900047220.012
response to axon injuryGO:004867810.012
regulation of coagulationGO:0050818440.012
cellular response to dna damage stimulusGO:00069743790.011
glycoprotein biosynthetic processGO:0009101910.011
opioid receptor signaling pathwayGO:003800340.011
regulation of lipid metabolic processGO:0019216960.011
cytosolic calcium ion homeostasisGO:0051480890.011
positive regulation of immune system processGO:00026842830.011
negative regulation of phosphate metabolic processGO:00459362670.011
actin filament based processGO:00300292240.011
cell growthGO:00160491600.011
cellular biogenic amine metabolic processGO:0006576340.011
cyclic nucleotide metabolic processGO:0009187820.011
regulation of endopeptidase activityGO:00525481700.011
cyclic nucleotide mediated signalingGO:0019935260.011
protein localization to membraneGO:00726571600.011
purine nucleoside catabolic processGO:00061523980.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
ribonucleotide catabolic processGO:00092614050.011
regulation of cellular component biogenesisGO:00440872810.011
ketone catabolic processGO:004218230.011
rna processingGO:00063962550.011
cell projection organizationGO:00300302520.011
somatostatin signaling pathwayGO:003817010.011
lymphocyte proliferationGO:0046651700.011
spermatid differentiationGO:004851540.011
positive regulation of fibrinolysisGO:005191940.011
purine ribonucleoside catabolic processGO:00461303980.011
plasminogen activationGO:0031639110.011
cellular response to reactive oxygen speciesGO:0034614500.011
chromatin organizationGO:00063253510.011
positive regulation of secretionGO:00510471160.011
oocyte developmentGO:004859910.011
oocyte differentiationGO:000999420.011
nervous system developmentGO:00073992930.011
inflammatory responseGO:0006954790.011
glycosyl compound catabolic processGO:19016584130.011
mitotic cell cycle processGO:19030472860.011
angiogenesisGO:00015251470.011
positive regulation of cellular component organizationGO:00511303760.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of transmembrane transportGO:00347621390.011
lymphocyte mediated immunityGO:0002449480.011
negative regulation of transferase activityGO:00513481240.011
regulation of monooxygenase activityGO:0032768220.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
negative regulation of protein phosphorylationGO:00019331400.011
neutral lipid catabolic processGO:0046461120.011
long chain fatty acid metabolic processGO:0001676300.011
blood vessel developmentGO:00015681720.011
response to hypoxiaGO:0001666960.011
Rat
cell developmentGO:00484683280.011
response to extracellular stimulusGO:0009991850.010
Rat
leukocyte proliferationGO:0070661740.010
lipid homeostasisGO:0055088390.010
regulation of immune effector processGO:0002697910.010
regulation of anion transportGO:0044070250.010
long term memoryGO:000761620.010
reactive nitrogen species metabolic processGO:200105730.010
negative regulation of kinase activityGO:00336731060.010
hemopoiesisGO:00300971800.010
detection of stimulusGO:0051606850.010
response to glucagonGO:003376210.010
regulation of intestinal epithelial structure maintenanceGO:006073010.010
calcium ion transmembrane transportGO:0070588760.010
purine nucleotide biosynthetic processGO:0006164840.010
Rat
protein localization to nucleusGO:00345041360.010
cholesterol metabolic processGO:0008203280.010
circulatory system developmentGO:00723592620.010
leukocyte mediated immunityGO:0002443590.010
regulation of nucleotide metabolic processGO:00061402690.010
nucleotide biosynthetic processGO:00091651090.010
Rat
negative regulation of organelle organizationGO:00106391260.010
quorum sensing involved in interaction with hostGO:005210610.010
positive regulation of cell proliferationGO:00082843010.010
ameboidal type cell migrationGO:00016671350.010
response to starvationGO:0042594590.010
protein importGO:00170381300.010

PKLR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.197
inherited metabolic disorderDOID:6552420.114
hematopoietic system diseaseDOID:741000.044
immune system diseaseDOID:29141550.044
nervous system diseaseDOID:8634310.021
eye and adnexa diseaseDOID:14921500.021
sensory system diseaseDOID:00501552030.021
eye diseaseDOID:56141490.018
retinal diseaseDOID:56791180.018
disease of cellular proliferationDOID:145661740.014
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
central nervous system diseaseDOID:3311860.013
anemiaDOID:2355550.012
acquired metabolic diseaseDOID:0060158580.012
cardiovascular system diseaseDOID:12871060.011
retinal degenerationDOID:8466890.011
neurodegenerative diseaseDOID:12891020.010