Homo sapiens

83 known processes

SUFU

suppressor of fused homolog (Drosophila)

(Aliases: SUFUXL,PRO1280,SUFUH)

SUFU biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ventral spinal cord interneuron differentiationGO:002151411.000
Mouse
spinal cord dorsal ventral patterningGO:002151321.000
Mouse
neuron fate commitmentGO:004866320.996
Mouse
heart formationGO:006091420.993
cell differentiation in spinal cordGO:002151510.990
Mouse
spinal cord developmentGO:002151040.990
Mouse
cranial nerve developmentGO:002154540.987
cell fate commitment involved in pattern specificationGO:006058110.984
Mouse
positive regulation of smoothened signaling pathwayGO:004588040.983
organ formationGO:004864530.965
canonical wnt signaling pathwayGO:00600701160.956
skin developmentGO:0043588760.910
Mouse
abducens nerve developmentGO:002156010.894
chromatin organizationGO:00063253510.851
muscle cell fate commitmentGO:004269340.848
negative regulation of wnt signaling pathwayGO:0030178690.839
ventral spinal cord developmentGO:002151710.836
Mouse
retinal ganglion cell axon guidanceGO:003129020.809
smoothened signaling pathwayGO:0007224140.809
Mouse
dicarboxylic acid catabolic processGO:004364990.792
neural tube patterningGO:002153220.773
Mouse
blastoderm segmentationGO:000735020.748
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.747
protein targeting to peroxisomeGO:0006625150.699
female gamete generationGO:000729220.665
brain morphogenesisGO:004885410.646
epidermis developmentGO:0008544590.641
wnt signaling pathwayGO:00160551560.621
peroxisomal transportGO:0043574150.583
dna conformation changeGO:00711031130.583
nerve developmentGO:002167540.559
cuticle developmentGO:004233510.557
spinal cord patterningGO:002151120.557
Mouse
establishment of protein localization to organelleGO:00725941720.544
Mouse
regulation of cellular ketone metabolic processGO:0010565500.540
protein importGO:00170381300.538
Mouse
appendage developmentGO:0048736230.526
regulation of smoothened signaling pathwayGO:000858960.506
Mouse
epithelium developmentGO:00604292270.501
Mouse
segmentationGO:003528240.493
response to virusGO:00096151260.481
negative regulation of canonical wnt signaling pathwayGO:0090090550.480
positive regulation of dna replicationGO:0045740350.467
osteoblast differentiationGO:0001649920.466
regulation of canonical wnt signaling pathwayGO:0060828880.464
limb morphogenesisGO:0035108160.453
hindbrain developmentGO:003090230.447
anatomical structure formation involved in morphogenesisGO:00486462840.438
Mouse
epidermal cell differentiationGO:0009913450.432
ossificationGO:00015031210.354
regulation of dna metabolic processGO:00510521530.350
oogenesisGO:004847720.350
dna replicationGO:00062601160.302
response to biotic stimulusGO:00096072760.293
intracellular protein transportGO:00068862700.277
Mouse
appendage morphogenesisGO:0035107160.276
dicarboxylic acid metabolic processGO:0043648290.261
positive regulation of dna metabolic processGO:0051054730.261
protein localization to organelleGO:00333652800.255
Mouse
neural nucleus developmentGO:0048857470.246
endocrine system developmentGO:0035270260.239
transmembrane transportGO:00550853990.237
regulation of wnt signaling pathwayGO:00301111230.232
carboxylic acid catabolic processGO:0046395710.209
regulation of gene expression epigeneticGO:0040029730.194
dosage compensationGO:000754930.194
response to other organismGO:00517072610.191
positive regulation of cell cycle processGO:00900681060.191
small molecule biosynthetic processGO:00442831570.176
peroxisome organizationGO:0007031280.173
autonomic nervous system developmentGO:004848310.170
regulation of dna replicationGO:0006275680.163
cell cycle phase transitionGO:00447701730.159
regulation of mitotic cell cycle phase transitionGO:19019901180.156
post embryonic developmentGO:000979120.149
regulation of cell cycle phase transitionGO:19019871260.148
carboxylic acid biosynthetic processGO:0046394970.147
fatty acid biosynthetic processGO:0006633460.141
epithelial cell differentiationGO:00308551410.136
limb developmentGO:0060173230.130
cellular ketone metabolic processGO:0042180800.129
somatic muscle developmentGO:000752510.126
tissue morphogenesisGO:0048729960.126
Mouse
mitotic cell cycle processGO:19030472860.125
establishment of protein localization to peroxisomeGO:0072663150.124
regulation of cell cycle processGO:00105642660.121
positive regulation of cell cycleGO:00457871400.118
intracellular protein transmembrane transportGO:0065002240.116
positive regulation of epithelial cell differentiationGO:0030858140.115
heart developmentGO:0007507950.110
Mouse
organic acid biosynthetic processGO:0016053970.110
cell cycle g1 s phase transitionGO:0044843800.109
heart morphogenesisGO:0003007480.105
Mouse
regulation of ligase activityGO:0051340290.105
response to external biotic stimulusGO:00432072610.105
regulation of mitotic cell cycleGO:00073461890.103
single organism cellular localizationGO:19025803320.100
Mouse
regulation of microtubule based processGO:0032886740.097
monocarboxylic acid metabolic processGO:00327871850.096
regulation of cell cycleGO:00517263930.093
small molecule catabolic processGO:0044282920.092
regulation of neural precursor cell proliferationGO:200017740.090
cellular component disassemblyGO:0022411920.089
positive regulation of fatty acid biosynthetic processGO:004572350.086
cellular lipid metabolic processGO:00442553030.086
negative regulation of cytoskeleton organizationGO:0051494450.084
cytoplasmic transportGO:00164823790.082
Mouse
mitotic cell cycle phase transitionGO:00447721620.081
mitotic cell cycleGO:00002783260.081
regulation of cell differentiationGO:00455953930.081
sex determinationGO:000753030.080
positive regulation of cell proliferationGO:00082843010.079
regulation of cellular amino acid metabolic processGO:000652160.078
g1 s transition of mitotic cell cycleGO:0000082780.076
chemotaxisGO:00069351570.075
forebrain dorsal ventral pattern formationGO:002179810.074
central nervous system developmentGO:00074171230.071
Mouse
eye morphogenesisGO:0048592160.068
monocarboxylic acid biosynthetic processGO:0072330670.066
regulation of cell developmentGO:00602841610.065
neuron differentiationGO:00301821380.064
Mouse
positive regulation of lipid metabolic processGO:0045834500.064
cardiovascular system developmentGO:00723582620.063
Mouse
organic acid catabolic processGO:0016054710.063
intracellular protein transmembrane importGO:0044743230.061
cell morphogenesisGO:00009022960.061
myoblast fusionGO:000752010.061
cellular response to virusGO:009858690.059
microtubule cytoskeleton organizationGO:00002261760.059
regulation of cell cycle g1 s phase transitionGO:1902806420.058
regulation of neurogenesisGO:0050767820.057
regulation of protein depolymerizationGO:1901879220.056
cell projection organizationGO:00300302520.055
lipid biosynthetic processGO:00086101770.055
negative regulation of organelle organizationGO:00106391260.054
central nervous system neuron differentiationGO:002195390.053
Mouse
negative regulation of cell proliferationGO:00082852280.053
forebrain developmentGO:0030900260.052
positive regulation of fatty acid metabolic processGO:0045923110.051
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.051
cell proliferation in forebrainGO:002184610.051
regionalizationGO:0003002290.050
Mouse
embryonic morphogenesisGO:0048598850.050
Mouse
determination of adult lifespanGO:000834020.050
regulation of epithelial cell differentiationGO:0030856240.048
taxisGO:00423301570.047
gland developmentGO:0048732480.047
cilium morphogenesisGO:0060271750.046
cellular component morphogenesisGO:00329893140.046
hematopoietic or lymphoid organ developmentGO:00485341860.045
positive regulation of mitotic cell cycle phase transitionGO:1901992190.044
muscle structure developmentGO:0061061980.044
positive regulation of immune system processGO:00026842830.044
protein import into nucleusGO:00066061040.043
Mouse
single organism nuclear importGO:19025931040.043
Mouse
regulation of microtubule cytoskeleton organizationGO:0070507610.042
protein localization to peroxisomeGO:0072662150.042
head developmentGO:00603221080.042
amine metabolic processGO:0009308440.042
cell projection morphogenesisGO:00488581290.042
ion transmembrane transportGO:00342203380.042
protein targeting to nucleusGO:00447441040.041
Mouse
multicellular organismal agingGO:001025930.041
regulation of fatty acid metabolic processGO:0019217240.041
embryonic digestive tract morphogenesisGO:004855720.040
regulation of g1 s transition of mitotic cell cycleGO:2000045400.039
positive regulation of cell differentiationGO:00455972110.038
morphogenesis of embryonic epitheliumGO:001633140.038
Mouse
cell part morphogenesisGO:00329901370.038
cellular amino acid metabolic processGO:00065201160.038
nervous system developmentGO:00073992930.038
Mouse
syncytium formation by plasma membrane fusionGO:000076820.038
generation of neuronsGO:00486991520.037
Mouse
protein import into peroxisome matrixGO:0016558110.036
positive regulation of lipid biosynthetic processGO:0046889220.036
positive regulation of mitotic cell cycleGO:0045931600.036
cilium organizationGO:0044782680.035
neuroblast proliferationGO:000740540.035
microtubule based processGO:00070172100.035
cell fate commitmentGO:0045165270.035
Mouse
protein depolymerizationGO:0051261300.034
protein targetingGO:00066051870.034
Mouse
nuclear transportGO:00511691790.033
Mouse
brain developmentGO:0007420970.033
limbic system developmentGO:002176130.033
cell developmentGO:00484683280.033
cilium assemblyGO:0042384630.033
protein ubiquitinationGO:00165673140.033
Mouse
cerebral cortex cell migrationGO:002179530.032
odontogenesisGO:0042476250.032
sensory organ morphogenesisGO:0090596210.032
regulation of sequence specific dna binding transcription factor activityGO:00510902110.032
regulation of cytoskeleton organizationGO:00514931770.032
protein complex disassemblyGO:0043241520.032
neuron projection developmentGO:00311751060.032
tube developmentGO:00352951250.031
Mouse
regulation of cartilage developmentGO:0061035120.031
ribonucleotide catabolic processGO:00092614050.031
lipid metabolic processGO:00066293810.031
single organism reproductive processGO:0044702980.031
positive regulation of cellular catabolic processGO:00313312840.031
negative regulation of apoptotic processGO:00430663160.031
mammary gland morphogenesisGO:006044320.031
microtubule polymerization or depolymerizationGO:0031109370.030
cerebellum developmentGO:002154920.029
protein transmembrane transportGO:0071806250.029
reproductive processGO:00224141060.029
negative regulation of cellular amino acid metabolic processGO:004576320.029
muscle cell differentiationGO:0042692630.029
mammary gland formationGO:006059210.028
cellular macromolecule catabolic processGO:00442653800.028
Mouse
macromolecular complex disassemblyGO:0032984600.028
nucleoside triphosphate catabolic processGO:00091433940.028
cellular amine metabolic processGO:0044106410.028
small gtpase mediated signal transductionGO:0007264780.028
diencephalon developmentGO:002153660.028
cellular macromolecular complex assemblyGO:00346223240.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
negative regulation of cellular component organizationGO:00511292350.027
regulation of microtubule polymerization or depolymerizationGO:0031110270.027
purine nucleotide catabolic processGO:00061954050.027
regulation of protein transportGO:00512232130.027
Mouse
negative regulation of protein complex disassemblyGO:0043242200.027
leukocyte activationGO:00453211640.027
negative regulation of multicellular organismal processGO:00512413170.027
Mouse
skeletal system developmentGO:0001501790.027
protein oligomerizationGO:00512591730.027
regulation of growth rateGO:004000910.027
organophosphate catabolic processGO:00464344300.027
purine nucleoside triphosphate catabolic processGO:00091463920.026
negative regulation of phosphorylationGO:00423261740.026
cell morphogenesis involved in differentiationGO:00009041440.026
tongue developmentGO:004358610.026
protein localization to nucleusGO:00345041360.025
Mouse
cell activationGO:00017752130.025
cellular protein complex assemblyGO:00436231880.025
metal ion transportGO:00300012720.025
eye developmentGO:0001654420.025
pattern specification processGO:0007389430.025
Mouse
immune system developmentGO:00025201950.024
vesicle mediated transportGO:00161923710.024
positive regulation of ligase activityGO:0051351190.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
nucleocytoplasmic transportGO:00069131760.024
Mouse
positive regulation of developmental processGO:00510943140.024
protein polymerizationGO:0051258710.023
proteasomal protein catabolic processGO:00104981760.023
forebrain generation of neuronsGO:002187230.023
gland morphogenesisGO:002261280.023
histone modificationGO:00165702510.023
post embryonic organ developmentGO:004856910.022
specification of organ identityGO:001009230.022
neurological system processGO:00508771630.022
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.022
negative regulation of protein modification processGO:00314002000.022
Mouse
embryonic epithelial tube formationGO:000183840.022
Mouse
positive regulation of leukocyte activationGO:0002696800.021
fatty acid metabolic processGO:00066311150.021
positive regulation of transferase activityGO:00513472270.021
memoryGO:000761330.021
multi organism reproductive processGO:0044703540.021
cytokine productionGO:00018162470.021
negative regulation of programmed cell deathGO:00430693210.021
positive regulation of nucleotide catabolic processGO:00308131850.021
positive regulation of protein phosphorylationGO:00019343130.021
system processGO:00030083490.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
microtubule depolymerizationGO:0007019180.020
negative regulation of cell deathGO:00605483450.020
cell fate specificationGO:000170880.020
Mouse
negative regulation of protein depolymerizationGO:1901880170.020
regulation of cellular amine metabolic processGO:0033238110.020
chordate embryonic developmentGO:0043009340.020
Mouse
protein catabolic processGO:00301633250.020
Mouse
regulation of mapk cascadeGO:00434082620.020
purine nucleoside monophosphate catabolic processGO:00091281580.020
regulation of lipid metabolic processGO:0019216960.020
positive regulation of catabolic processGO:00098963100.019
nucleotide catabolic processGO:00091664080.019
hemopoiesisGO:00300971800.019
regulation of nucleotide metabolic processGO:00061402690.019
inner ear morphogenesisGO:004247240.019
negative regulation of smoothened signaling pathwayGO:004587930.019
Mouse
innate immune responseGO:00450871780.019
pyridine containing compound metabolic processGO:0072524180.019
defense responseGO:00069523150.019
hippocampus developmentGO:002176610.019
forebrain regionalizationGO:002187130.018
detection of chemical stimulus involved in sensory perceptionGO:0050907330.018
regulation of fatty acid biosynthetic processGO:004230490.018
cranial nerve morphogenesisGO:002160210.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
regulation of protein localization to nucleusGO:1900180850.018
Mouse
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
protein processingGO:00164852260.018
Mouse
stem cell divisionGO:001714520.018
signal transduction by phosphorylationGO:00230142970.018
striated muscle cell differentiationGO:0051146430.018
ras protein signal transductionGO:0007265730.017
embryo developmentGO:00097901230.017
Mouse
striated muscle tissue developmentGO:0014706590.017
response to abiotic stimulusGO:00096283360.017
atp metabolic processGO:00460341760.017
regulation of protein maturationGO:19033171500.017
Mouse
regulation of protein catabolic processGO:00421761550.017
Mouse
regulation of intracellular transportGO:00323861950.017
Mouse
purine ribonucleoside monophosphate catabolic processGO:00091691580.017
negative regulation of microtubule depolymerizationGO:0007026120.017
regulation of establishment of protein localizationGO:00702012420.017
Mouse
regulation of reactive oxygen species metabolic processGO:2000377410.017
positive regulation of neural precursor cell proliferationGO:200017920.017
locomotory behaviorGO:000762610.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
sensory organ developmentGO:0007423520.016
positive regulation of t cell activationGO:0050870540.016
oocyte developmentGO:004859910.016
negative regulation of catalytic activityGO:00430863350.016
positive regulation of nucleoside metabolic processGO:00459791860.016
ubiquitin dependent protein catabolic processGO:00065112060.016
Mouse
metencephalon developmentGO:002203720.015
neuron projection morphogenesisGO:0048812500.015
dendrite developmentGO:0016358240.015
thymocyte apoptotic processGO:007024220.015
regulation of protein localizationGO:00328802960.015
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.015
Mouse
oocyte differentiationGO:000999420.015
peripheral nervous system developmentGO:000742220.015
cell morphogenesis involved in neuron differentiationGO:0048667440.015
positive regulation of lymphocyte activationGO:0051251730.015
spermatid differentiationGO:004851540.015
posttranscriptional regulation of gene expressionGO:00106082130.015
defense response to virusGO:0051607710.015
anterior posterior axis specificationGO:000994820.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
immune effector processGO:00022521590.014
positive regulation of chondrocyte differentiationGO:003233240.014
regulation of secretion by cellGO:19035301770.014
regulation of protein processingGO:00706131500.014
Mouse
purine ribonucleoside catabolic processGO:00461303980.014
negative regulation of protein phosphorylationGO:00019331400.014
positive regulation of apoptotic processGO:00430652460.014
cation transportGO:00068123310.014
negative regulation of cell cycleGO:00457861930.014
neuromuscular junction developmentGO:000752830.014
t cell differentiationGO:0030217290.013
chemical homeostasisGO:00488783060.013
positive regulation of cellular amine metabolic processGO:003324070.013
activation of immune responseGO:00022531140.013
chromatin modificationGO:00165682980.013
atp catabolic processGO:00062001570.013
optic nerve developmentGO:002155420.013
regulation of proteolysisGO:00301622930.013
Mouse
leukocyte apoptotic processGO:0071887310.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
cellular response to oxygen containing compoundGO:19017012760.013
dephosphorylationGO:00163112090.013
positive regulation of cellular component organizationGO:00511303760.013
t cell differentiation in thymusGO:003307740.013
cation transmembrane transportGO:00986552380.013
stem cell developmentGO:0048864690.013
divalent inorganic cation transportGO:00725111580.013
cellular protein catabolic processGO:00442572610.013
Mouse
protein polyubiquitinationGO:00002091100.013
regulation of synaptic plasticityGO:004816730.013
inorganic ion transmembrane transportGO:00986602310.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
positive regulation of organelle organizationGO:00106381950.013
lipid localizationGO:00108761060.012
regenerationGO:003109940.012
regulation of actin cytoskeleton organizationGO:00329561160.012
negative regulation of intracellular signal transductionGO:19025321830.012
covalent chromatin modificationGO:00165692540.012
intracellular receptor signaling pathwayGO:00305221040.012
regulation of ion transmembrane transportGO:00347651320.012
positive regulation of gtp catabolic processGO:00331261660.012
protein modification by small protein removalGO:0070646920.012
nuclear importGO:00511701060.012
Mouse
positive regulation of nucleotide metabolic processGO:00459812300.012
endosomal transportGO:00161971290.012
modification dependent protein catabolic processGO:00199412090.012
Mouse
dna repairGO:00062811980.012
axonogenesisGO:0007409310.012
protein acylationGO:00435431380.012
guanosine containing compound metabolic processGO:19010682440.012
engulfment of apoptotic cellGO:004365220.012
compound eye developmentGO:004874910.012
regulation of viral processGO:00507921030.012
epithelial cell proliferationGO:00506731280.012
guanosine containing compound catabolic processGO:19010692390.012
regulation of leukocyte differentiationGO:1902105610.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
protein maturationGO:00516042330.012
Mouse
spermatid developmentGO:000728640.012
regulation of cellular protein catabolic processGO:1903362960.012
Mouse
anterior posterior axis specification embryoGO:000859520.012
blood vessel developmentGO:00015681720.012
sensory perceptionGO:00076001030.011
purine nucleoside catabolic processGO:00061523980.011
regulation of purine nucleotide catabolic processGO:00331212050.011
neurotransmitter secretionGO:000726940.011
divalent metal ion transportGO:00708381520.011
angiogenesisGO:00015251470.011
negative regulation of cellular amine metabolic processGO:003323930.011
gtp catabolic processGO:00061842370.011
ribonucleoside catabolic processGO:00424544060.011
peptidyl lysine modificationGO:00182051440.011
reproductionGO:0000003630.011
regulation of apoptotic signaling pathwayGO:20012331750.011
somatic stem cell maintenanceGO:003501940.011
purine ribonucleoside metabolic processGO:00461284370.011
regulation of transferase activityGO:00513383550.011
cell projection assemblyGO:00300311260.011
neuron developmentGO:00486661130.011
negative regulation of catabolic processGO:00098951040.011
Mouse
purine containing compound catabolic processGO:00725234110.011
blood vessel morphogenesisGO:00485141620.011
glycosyl compound catabolic processGO:19016584130.011
positive regulation of intracellular transportGO:00323881040.011
regulation of response to external stimulusGO:00321012220.011
circulatory system developmentGO:00723592620.011
Mouse
positive regulation of hydrolase activityGO:00513453310.011
regulation of nervous system developmentGO:0051960880.011
Mouse
adult locomotory behaviorGO:000834410.011
negative regulation of protein metabolic processGO:00512483910.011
Mouse
reactive oxygen species metabolic processGO:0072593750.011
cellular response to organic cyclic compoundGO:00714071270.011
long term memoryGO:000761620.011
matingGO:000761810.011
interspecies interaction between organismsGO:00444191560.011
response to hormoneGO:00097251750.011
regulation of protein serine threonine kinase activityGO:00719001790.011
thymus developmentGO:004853830.010
axis elongationGO:000340140.010
negative regulation of transferase activityGO:00513481240.010
motor neuron axon guidanceGO:000804520.010
protein autophosphorylationGO:00467771230.010
regulation of glial cell differentiationGO:004568530.010
axon developmentGO:0061564340.010
meiosis iGO:000712740.010
cellular response to cytokine stimulusGO:00713451810.010
neural tube formationGO:000184130.010
Mouse
rna interferenceGO:001624640.010
i kappab kinase nf kappab signalingGO:00072491660.010
negative regulation of phosphorus metabolic processGO:00105632670.010
response to growth factorGO:00708482050.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
apoptotic signaling pathwayGO:00971902680.010
regulation of protein complex disassemblyGO:0043244280.010
rhythmic behaviorGO:000762220.010
regulation of ras protein signal transductionGO:00465781550.010
response to fungusGO:000962040.010
ribonucleoside triphosphate catabolic processGO:00092033910.010
negative regulation of proteolysisGO:00458611320.010
Mouse

SUFU disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:0080006550.101
bone diseaseDOID:0080001880.101
connective tissue diseaseDOID:651090.101
musculoskeletal system diseaseDOID:172230.101
cancerDOID:1621670.029
disease of cellular proliferationDOID:145661740.029
organ system cancerDOID:00506861640.029
disease of metabolismDOID:00146672950.023
inherited metabolic disorderDOID:6552420.023
central nervous system diseaseDOID:3311860.019
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.014
nervous system cancerDOID:3093120.001
central nervous system cancerDOID:362090.001
meningiomaDOID:356560.001
familial meningiomaDOID:458660.001
brain cancerDOID:131940.000
nevoid basal cell carcinoma syndromeDOID:251230.000
infratentorial cancerDOID:470630.000
medulloblastomaDOID:005090230.000