Homo sapiens

172 known processes

BRD4

bromodomain containing 4

(Aliases: HUNKI,MCAP,CAP,HUNK1)

BRD4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063253510.881
covalent chromatin modificationGO:00165692540.815
Mouse
histone modificationGO:00165702510.683
Mouse
phagocytosis recognitionGO:000691030.562
chromatin modificationGO:00165682980.490
phosphorylation of rna polymerase ii c terminal domainGO:007081630.481
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.318
cellular component morphogenesisGO:00329893140.294
hemopoiesisGO:00300971800.238
hematopoietic or lymphoid organ developmentGO:00485341860.223
demethylationGO:0070988370.214
regulation of anatomical structure morphogenesisGO:00226032860.208
protein demethylationGO:0006482170.187
mitotic cell cycleGO:00002783260.174
rna splicingGO:00083801310.164
actin filament based processGO:00300292240.162
immune system developmentGO:00025201950.149
anatomical structure formation involved in morphogenesisGO:00486462840.138
post embryonic developmentGO:000979120.135
Worm Fly
histone demethylationGO:0016577150.131
rna processingGO:00063962550.126
actin filament organizationGO:00070151280.125
myeloid cell differentiationGO:00300991170.125
actin cytoskeleton organizationGO:00300362070.124
growthGO:00400072020.123
Mouse
cardiovascular system developmentGO:00723582620.117
cell competition in a multicellular organismGO:003521210.114
cell morphogenesisGO:00009022960.112
multicellular organismal agingGO:001025930.109
tube developmentGO:00352951250.108
mrna metabolic processGO:00160711750.104
mapk cascadeGO:00001652880.102
segmentationGO:003528240.100
Fly
mitotic cell cycle phase transitionGO:00447721620.099
stress activated mapk cascadeGO:0051403930.087
determination of adult lifespanGO:000834020.082
erythrocyte developmentGO:004882130.078
circulatory system developmentGO:00723592620.078
leukocyte differentiationGO:0002521980.077
regulation of cell morphogenesisGO:00226041530.075
cell developmentGO:00484683280.073
negative regulation of cell deathGO:00605483450.068
morphogenesis of embryonic epitheliumGO:001633140.066
regulation of stress activated mapk cascadeGO:0032872840.063
dna repairGO:00062811980.062
regulation of mapk cascadeGO:00434082620.062
vesicle mediated transportGO:00161923710.061
response to abiotic stimulusGO:00096283360.060
cellular macromolecule catabolic processGO:00442653800.060
t cell differentiation in thymusGO:003307740.057
embryonic epithelial tube formationGO:000183840.056
regulation of cellular amino acid metabolic processGO:000652160.054
transcription elongation from rna polymerase ii promoterGO:0006368180.054
jnk cascadeGO:0007254800.054
regulation of cell cycleGO:00517263930.053
neural tube formationGO:000184130.053
primary neural tube formationGO:001402030.053
ras protein signal transductionGO:0007265730.053
regulation of jnk cascadeGO:0046328730.053
mrna splicing via spliceosomeGO:0000398890.052
regulation of cell cycle processGO:00105642660.051
erythrocyte homeostasisGO:0034101310.050
mrna processingGO:00063971330.049
negative regulation of phosphorus metabolic processGO:00105632670.048
blood vessel morphogenesisGO:00485141620.047
negative regulation of apoptotic processGO:00430663160.047
methylationGO:00322591060.047
embryonic camera type eye morphogenesisGO:004859620.045
regulation of transferase activityGO:00513383550.045
embryonic camera type eye developmentGO:003107620.045
ribonucleoside triphosphate metabolic processGO:00091994120.044
vasculature developmentGO:00019441810.044
cellular response to dna damage stimulusGO:00069743790.044
histone methylationGO:0016571600.043
stress activated protein kinase signaling cascadeGO:0031098940.043
positive regulation of dna templated transcription elongationGO:0032786180.043
chromatin assembly or disassemblyGO:0006333780.042
Human
establishment of tissue polarityGO:000716430.042
small gtpase mediated signal transductionGO:0007264780.042
blood vessel developmentGO:00015681720.042
negative regulation of cell cycle processGO:00109481210.041
regulation of cellular response to stressGO:00801352440.041
positive regulation of cell differentiationGO:00455972110.040
protein autophosphorylationGO:00467771230.040
negative regulation of cell cycleGO:00457861930.040
negative regulation of phosphorylationGO:00423261740.040
female gamete generationGO:000729220.039
wnt signaling pathwayGO:00160551560.039
urogenital system developmentGO:0001655650.039
regulation of cell differentiationGO:00455953930.038
peripheral nervous system developmentGO:000742220.038
mitotic cell cycle processGO:19030472860.038
membrane organizationGO:00610242920.038
angiogenesisGO:00015251470.037
purine nucleoside triphosphate metabolic processGO:00091444120.037
purine nucleoside triphosphate catabolic processGO:00091463920.037
purine ribonucleoside triphosphate catabolic processGO:00092073910.037
purine ribonucleoside catabolic processGO:00461303980.036
regulation of response to dna damage stimulusGO:2001020940.036
rna splicing via transesterification reactionsGO:0000375900.036
cellular response to cytokine stimulusGO:00713451810.036
positive regulation of cellular component organizationGO:00511303760.035
positive regulation of cellular catabolic processGO:00313312840.034
nervous system developmentGO:00073992930.034
Worm
positive regulation of cellular amino acid metabolic processGO:004576430.033
amine metabolic processGO:0009308440.033
purine ribonucleoside metabolic processGO:00461284370.033
proteasomal protein catabolic processGO:00104981760.033
cellular amino acid metabolic processGO:00065201160.033
regulation of mitotic cell cycle phase transitionGO:19019901180.033
regulation of cell developmentGO:00602841610.033
cellular amine metabolic processGO:0044106410.032
dna conformation changeGO:00711031130.032
Human
cellular response to growth factor stimulusGO:00713631970.032
oogenesisGO:004847720.032
posttranscriptional regulation of gene expressionGO:00106082130.032
t cell activationGO:0042110990.032
protein methylationGO:0006479740.031
biological adhesionGO:00226103310.031
positive regulation of mapk cascadeGO:00434101900.031
chromatin assemblyGO:0031497610.031
Human
cell cycle phase transitionGO:00447701730.030
protein dealkylationGO:0008214170.030
protein catabolic processGO:00301633250.029
epithelium developmentGO:00604292270.029
anterior posterior axis specification embryoGO:000859520.029
Fly
regulation of growthGO:00400081650.029
kidney developmentGO:0001822530.029
neurogenesisGO:00220081690.029
Worm
embryonic eye morphogenesisGO:004804820.029
nucleoside phosphate catabolic processGO:19012924120.029
eye developmentGO:0001654420.028
protein modification by small protein conjugationGO:00324463420.028
tube closureGO:006060630.028
negative regulation of programmed cell deathGO:00430693210.028
negative regulation of protein metabolic processGO:00512483910.028
regulation of protein kinase activityGO:00458592890.028
cell fate determinationGO:000170930.028
negative regulation of intracellular signal transductionGO:19025321830.027
regulation of protein serine threonine kinase activityGO:00719001790.027
endocytosisGO:00068971590.027
positive regulation of catabolic processGO:00098963100.027
positive regulation of immune system processGO:00026842830.027
regulation of response to external stimulusGO:00321012220.027
positive regulation of developmental processGO:00510943140.027
intracellular protein transportGO:00068862700.026
regulation of proteasomal protein catabolic processGO:0061136870.026
regulation of histone modificationGO:0031056470.026
glycosyl compound catabolic processGO:19016584130.026
regulation of stress activated protein kinase signaling cascadeGO:0070302850.026
establishment of planar polarityGO:000173630.026
regulation of cellular protein catabolic processGO:1903362960.026
trophectodermal cell differentiationGO:000182930.026
cellular macromolecular complex assemblyGO:00346223240.026
Human
protein dna complex subunit organizationGO:0071824800.026
Human
protein alkylationGO:0008213740.025
cell activationGO:00017752130.025
ribonucleoside catabolic processGO:00424544060.025
regulation of mrna metabolic processGO:1903311530.025
neural tube closureGO:000184330.025
positive regulation of phosphorylationGO:00423273940.025
rho protein signal transductionGO:0007266260.025
regulation of cellular ketone metabolic processGO:0010565500.025
regulation of cell cycle phase transitionGO:19019871260.025
regulation of cellular amine metabolic processGO:0033238110.025
blastocyst developmentGO:000182430.025
Mouse
embryonic morphogenesisGO:0048598850.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
dna templated transcription elongationGO:0006354250.024
neuron differentiationGO:00301821380.024
tripartite regional subdivisionGO:000735120.023
Fly
taxisGO:00423301570.023
cell adhesionGO:00071553250.023
leukocyte activationGO:00453211640.023
regulation of sequence specific dna binding transcription factor activityGO:00510902110.023
regulation of dna metabolic processGO:00510521530.023
somitogenesisGO:000175620.023
compound eye developmentGO:004874910.023
renal system developmentGO:0072001630.022
positive regulation of cell cycleGO:00457871400.022
regulation of chromatin modificationGO:1903308510.022
regulation of chromatin organizationGO:1902275560.022
regulation of cytokine productionGO:00018172320.022
reproductive processGO:00224141060.022
nucleotide catabolic processGO:00091664080.022
negative regulation of phosphate metabolic processGO:00459362670.022
morphogenesis of a polarized epitheliumGO:000173830.022
response to growth factorGO:00708482050.022
positive regulation of nucleotide metabolic processGO:00459812300.022
dna dependent dna replicationGO:0006261440.022
heart developmentGO:0007507950.022
regulation of dna repairGO:0006282470.022
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.022
erk1 and erk2 cascadeGO:00703711040.021
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.021
secretion by cellGO:00329402260.021
t cell differentiationGO:0030217290.021
single organism membrane organizationGO:00448022680.021
negative regulation of mitotic cell cycle phase transitionGO:1901991850.021
somatic stem cell maintenanceGO:003501940.021
ubiquitin dependent protein catabolic processGO:00065112060.021
positive regulation of cellular amine metabolic processGO:003324070.021
metal ion transportGO:00300012720.021
gtp metabolic processGO:00460392390.021
positive regulation of dna metabolic processGO:0051054730.021
chemotaxisGO:00069351570.021
cellular response to oxygen containing compoundGO:19017012760.020
morphogenesis of an epitheliumGO:0002009600.020
axis elongationGO:000340140.020
regulation of proteolysisGO:00301622930.020
cell morphogenesis involved in differentiationGO:00009041440.020
intracellular receptor signaling pathwayGO:00305221040.020
regulation of nucleotide metabolic processGO:00061402690.020
tissue morphogenesisGO:0048729960.020
negative regulation of cellular protein metabolic processGO:00322693530.020
cell projection organizationGO:00300302520.020
apoptotic signaling pathwayGO:00971902680.020
regulation of protein catabolic processGO:00421761550.019
nucleoside triphosphate metabolic processGO:00091414220.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
macromolecule methylationGO:0043414970.019
organ formationGO:004864530.019
lymphocyte activationGO:00466491330.019
generation of neuronsGO:00486991520.019
Worm
regulation of chromosome organizationGO:00330441030.019
circadian behaviorGO:004851220.019
response to woundingGO:00096111680.019
neuron projection developmentGO:00311751060.019
neurological system processGO:00508771630.019
anterior posterior axis specificationGO:000994820.019
Fly
negative regulation of mitotic cell cycleGO:00459301020.019
lung developmentGO:0030324200.019
modification dependent protein catabolic processGO:00199412090.019
regulation of myeloid cell differentiationGO:0045637810.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
spermatid developmentGO:000728640.018
regulation of cell shapeGO:0008360480.018
cellular ketone metabolic processGO:0042180800.018
negative regulation of mapk cascadeGO:0043409560.018
regulation of wnt signaling pathwayGO:00301111230.018
dephosphorylationGO:00163112090.018
cytokine productionGO:00018162470.018
neuromuscular junction developmentGO:000752830.018
ribonucleotide catabolic processGO:00092614050.018
cell growthGO:00160491600.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
maintenance of locationGO:00512351120.018
cranial nerve developmentGO:002154540.018
positive regulation of nucleoside metabolic processGO:00459791860.018
regulation of cell motilityGO:20001452990.018
photoreceptor cell differentiationGO:004653020.018
embryo developmentGO:00097901230.017
Mouse Worm Fly
cellular response to endogenous stimulusGO:00714953360.017
histone acetylationGO:0016573930.017
Mouse
organ morphogenesisGO:00098871470.017
Fly
negative regulation of hydrolase activityGO:00513461820.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.017
neuron developmentGO:00486661130.017
nucleoside catabolic processGO:00091644080.017
positive regulation of protein phosphorylationGO:00019343130.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
gtp catabolic processGO:00061842370.017
regulation of cell morphogenesis involved in differentiationGO:0010769830.017
locomotory behaviorGO:000762610.017
myeloid cell homeostasisGO:0002262340.017
regulation of ras protein signal transductionGO:00465781550.017
response to temperature stimulusGO:0009266220.016
protein processingGO:00164852260.016
purine containing compound catabolic processGO:00725234110.016
single organism cellular localizationGO:19025803320.016
regulation of protein localizationGO:00328802960.016
regulation of protein stabilityGO:0031647870.016
negative regulation of developmental processGO:00510932470.016
regulation of mrna processingGO:0050684480.016
canonical wnt signaling pathwayGO:00600701160.016
regulation of response to woundingGO:19030341010.016
nucleoside triphosphate catabolic processGO:00091433940.016
regulation of map kinase activityGO:00434051080.016
epithelial cell differentiationGO:00308551410.016
negative regulation of cell differentiationGO:00455961710.016
myeloid leukocyte differentiationGO:0002573600.016
nerve developmentGO:002167540.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
purine ribonucleotide catabolic processGO:00091544040.016
cellular response to abiotic stimulusGO:00712141170.016
regulation of myeloid leukocyte differentiationGO:0002761390.015
protein localization to organelleGO:00333652800.015
secretionGO:00469032540.015
chemical homeostasisGO:00488783060.015
embryonic camera type eye formationGO:006090020.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
memoryGO:000761330.015
organophosphate catabolic processGO:00464344300.015
endochondral bone morphogenesisGO:006035030.015
regulation of rna splicingGO:0043484620.015
protein localization to cell surfaceGO:0034394280.015
oocyte developmentGO:004859910.015
developmental process involved in reproductionGO:0003006660.015
protein dna complex assemblyGO:0065004640.015
Human
signal transduction by phosphorylationGO:00230142970.015
negative regulation of catalytic activityGO:00430863350.015
sprouting angiogenesisGO:0002040290.015
cellular protein catabolic processGO:00442572610.015
dna packagingGO:0006323770.015
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.015
regulation of nucleotide catabolic processGO:00308112050.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
positive regulation of cell proliferationGO:00082843010.015
response to oxygen containing compoundGO:19017003690.015
modification dependent macromolecule catabolic processGO:00436322120.015
response to oxidative stressGO:00069791210.014
regulation of mitotic cell cycleGO:00073461890.014
histone lysine methylationGO:0034968500.014
spermatid differentiationGO:004851540.014
sensory organ developmentGO:0007423520.014
cellular ion homeostasisGO:00068731680.014
lens development in camera type eyeGO:000208820.014
nucleosome organizationGO:0034728660.014
Human
reproductionGO:0000003630.014
Worm
respiratory tube developmentGO:0030323200.014
purine nucleoside catabolic processGO:00061523980.014
system processGO:00030083490.014
immune responseGO:00069553070.014
inner ear morphogenesisGO:004247240.014
response to fungusGO:000962040.014
regenerationGO:003109940.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
negative regulation of protein modification processGO:00314002000.014
positive regulation of gtpase activityGO:00435471660.014
metal ion homeostasisGO:00550651690.013
regulation of gtpase activityGO:00430871800.013
purine nucleotide catabolic processGO:00061954050.013
protein maturationGO:00516042330.013
regulation of purine nucleotide metabolic processGO:19005422640.013
regulation of kinase activityGO:00435493140.013
microtubule cytoskeleton organizationGO:00002261760.013
blastocyst formationGO:000182530.013
regulation of axon guidanceGO:190266730.013
atp metabolic processGO:00460341760.013
negative regulation of stress activated mapk cascadeGO:0032873190.013
nucleosome assemblyGO:0006334500.013
Human
respiratory system developmentGO:0060541220.013
regulation of cellular component movementGO:00512703340.013
positive regulation of gtp catabolic processGO:00331261660.013
cell part morphogenesisGO:00329901370.013
defense responseGO:00069523150.013
guanosine containing compound metabolic processGO:19010682440.013
negative regulation of protein phosphorylationGO:00019331400.013
innate immune responseGO:00450871780.013
negative regulation of dna metabolic processGO:0051053570.013
cell projection morphogenesisGO:00488581290.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
negative regulation of cell cycle phase transitionGO:1901988890.013
forebrain generation of neuronsGO:002187230.012
regulation of nucleoside metabolic processGO:00091182090.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
positive regulation of erk1 and erk2 cascadeGO:0070374750.012
negative regulation of multicellular organismal processGO:00512413170.012
response to organic cyclic compoundGO:00140702040.012
positive regulation of cell migrationGO:00303351720.012
stem cell divisionGO:001714520.012
organonitrogen compound biosynthetic processGO:19015662000.012
organophosphate biosynthetic processGO:00904071630.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
positive regulation of transportGO:00510503360.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of mrna splicing via spliceosomeGO:0048024320.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
internal protein amino acid acetylationGO:00064751010.012
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.012
microtubule based processGO:00070172100.012
regulation of dna replicationGO:0006275680.012
regulation of cytoskeleton organizationGO:00514931770.012
regulation of meiotic cell cycleGO:005144540.012
ion transmembrane transportGO:00342203380.012
internal peptidyl lysine acetylationGO:0018393970.012
Mouse
cartilage development involved in endochondral bone morphogenesisGO:006035120.012
dna integrity checkpointGO:0031570710.012
positive regulation of apoptotic processGO:00430652460.011
camera type eye developmentGO:0043010250.011
neuroblast proliferationGO:000740540.011
response to hypoxiaGO:0001666960.011
wound healingGO:00420601150.011
regulation of cell activationGO:00508651250.011
protein oligomerizationGO:00512591730.011
regulation of protein maturationGO:19033171500.011
positive regulation of cellular component movementGO:00512721810.011
golgi vesicle transportGO:0048193800.011
positive regulation of hydrolase activityGO:00513453310.011
positive regulation of cytokine productionGO:00018191670.011
toxin transportGO:190199840.011
cardiac muscle tissue developmentGO:0048738390.011
protein ubiquitinationGO:00165673140.011
stem cell differentiationGO:0048863930.011
Worm
protein hydroxylationGO:001812690.011
dna replicationGO:00062601160.011
single organism reproductive processGO:0044702980.011
positive regulation of transferase activityGO:00513472270.011
regulation of microtubule based processGO:0032886740.011
cell projection assemblyGO:00300311260.011
meiosis iGO:000712740.011
cytoplasmic transportGO:00164823790.011
plasma membrane organizationGO:00070091150.011
positive regulation of chromosome organizationGO:2001252410.011
g1 s transition of mitotic cell cycleGO:0000082780.011
embryonic hindlimb morphogenesisGO:003511620.011
lipid metabolic processGO:00066293810.011
matingGO:000761810.011
muscle tissue developmentGO:0060537620.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
regulation of erk1 and erk2 cascadeGO:0070372990.011
oocyte differentiationGO:000999420.011
tube morphogenesisGO:0035239950.011
lens morphogenesis in camera type eyeGO:000208920.011
regulation of dephosphorylationGO:0035303960.011
glial cell migrationGO:000834740.011
cell cycle checkpointGO:00000751170.011
regulation of neuron projection developmentGO:0010975570.011
regulation of cell projection organizationGO:00313441070.011
syncytium formation by plasma membrane fusionGO:000076820.010
negative regulation of proteolysisGO:00458611320.010
peptidyl serine phosphorylationGO:00181051010.010
protein targetingGO:00066051870.010
regulation of leukocyte differentiationGO:1902105610.010
cellular cation homeostasisGO:00300031630.010
response to other organismGO:00517072610.010
response to external biotic stimulusGO:00432072610.010
small molecule biosynthetic processGO:00442831570.010
regulation of protein processingGO:00706131500.010
anatomical structure homeostasisGO:00602491000.010
sex differentiationGO:0007548450.010
cell cycle g2 m phase transitionGO:0044839430.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
regulation of ras gtpase activityGO:00323181280.010
rna interferenceGO:001624640.010
cell divisionGO:00513011680.010
mitotic nuclear divisionGO:00070671190.010
endomembrane system organizationGO:00102561960.010
cytokine mediated signaling pathwayGO:00192211090.010
retina development in camera type eyeGO:0060041150.010
guanosine containing compound catabolic processGO:19010692390.010
response to nitrogen compoundGO:19016981840.010

BRD4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.015
disease of cellular proliferationDOID:145661740.014
connective tissue diseaseDOID:651090.011
organ system cancerDOID:00506861640.011
cancerDOID:1621670.011
sensory system diseaseDOID:00501552030.011
nervous system diseaseDOID:8634310.011
bone diseaseDOID:0080001880.010
immune system diseaseDOID:29141550.010