Homo sapiens

0 known processes

PTPN18

protein tyrosine phosphatase, non-receptor type 18 (brain-derived)

(Aliases: PTP-HSCF,BDP1)

PTPN18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
plasma membrane raft assemblyGO:004485440.520
plasma membrane raft organizationGO:004485740.437
single organism membrane organizationGO:00448022680.231
membrane organizationGO:00610242920.144
protein dephosphorylationGO:0006470810.114
Human Mouse
membrane tubulationGO:0097320120.114
purine containing compound catabolic processGO:00725234110.104
caveola assemblyGO:007083640.102
purine nucleoside triphosphate catabolic processGO:00091463920.098
membrane protein proteolysisGO:0033619380.093
nucleoside phosphate catabolic processGO:19012924120.092
purine nucleoside catabolic processGO:00061523980.090
ras protein signal transductionGO:0007265730.084
organophosphate catabolic processGO:00464344300.082
glycosyl compound catabolic processGO:19016584130.079
nucleoside triphosphate metabolic processGO:00091414220.078
purine nucleotide catabolic processGO:00061954050.075
purine ribonucleoside triphosphate catabolic processGO:00092073910.074
purine ribonucleoside metabolic processGO:00461284370.072
negative regulation of multicellular organismal processGO:00512413170.071
positive regulation of catabolic processGO:00098963100.070
membrane protein ectodomain proteolysisGO:0006509330.070
ribonucleoside triphosphate metabolic processGO:00091994120.069
nucleoside triphosphate catabolic processGO:00091433940.068
guanosine containing compound catabolic processGO:19010692390.068
plasma membrane organizationGO:00070091150.065
positive regulation of hydrolase activityGO:00513453310.063
biological adhesionGO:00226103310.063
nucleoside catabolic processGO:00091644080.062
dephosphorylationGO:00163112090.062
Human Mouse
negative regulation of phosphorus metabolic processGO:00105632670.062
regulation of nucleoside metabolic processGO:00091182090.060
amine metabolic processGO:0009308440.058
regulation of protein localizationGO:00328802960.056
protein localization to organelleGO:00333652800.055
regulation of protein transportGO:00512232130.053
regulation of cell differentiationGO:00455953930.051
response to abiotic stimulusGO:00096283360.051
positive regulation of gtpase activityGO:00435471660.050
cell developmentGO:00484683280.049
cellular amine metabolic processGO:0044106410.048
negative regulation of cellular protein metabolic processGO:00322693530.047
post embryonic developmentGO:000979120.047
regulation of cellular component biogenesisGO:00440872810.046
regulation of gtp catabolic processGO:00331241800.046
protein catabolic processGO:00301633250.045
cellular chemical homeostasisGO:00550821800.044
regulation of kinase activityGO:00435493140.042
regulation of proteolysisGO:00301622930.042
system processGO:00030083490.042
actin mediated cell contractionGO:0070252120.042
multicellular organismal agingGO:001025930.042
positive regulation of nucleoside metabolic processGO:00459791860.041
cell activationGO:00017752130.040
Human
regulation of t cell activationGO:0050863770.040
Human
positive regulation of transportGO:00510503360.038
negative regulation of cellular component organizationGO:00511292350.038
positive regulation of protein catabolic processGO:0045732750.037
negative regulation of phosphorylationGO:00423261740.037
cellular response to endogenous stimulusGO:00714953360.037
carbohydrate metabolic processGO:00059752070.036
response to oxygen containing compoundGO:19017003690.036
regulation of cellular component movementGO:00512703340.036
regulation of nucleotide catabolic processGO:00308112050.036
membrane raft assemblyGO:000176570.036
positive regulation of nucleotide metabolic processGO:00459812300.035
negative regulation of phosphate metabolic processGO:00459362670.035
innate immune responseGO:00450871780.035
regenerationGO:003109940.034
positive regulation of cellular amine metabolic processGO:003324070.034
cellular lipid metabolic processGO:00442553030.034
regulation of protein catabolic processGO:00421761550.033
regulation of cellular amine metabolic processGO:0033238110.033
lipid metabolic processGO:00066293810.033
transmembrane transportGO:00550853990.033
regulation of lymphocyte activationGO:00512491030.033
Human
vesicle mediated transportGO:00161923710.033
neuromuscular junction developmentGO:000752830.033
cell fate determinationGO:000170930.032
regulation of anatomical structure morphogenesisGO:00226032860.032
cellular amino acid metabolic processGO:00065201160.032
oogenesisGO:004847720.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
actin cytoskeleton organizationGO:00300362070.030
negative regulation of protein modification processGO:00314002000.030
mitotic cell cycle phase transitionGO:00447721620.030
secretion by cellGO:00329402260.029
negative regulation of catalytic activityGO:00430863350.029
regulation of cell activationGO:00508651250.029
Human
single organism cell adhesionGO:00986021790.029
positive regulation of developmental processGO:00510943140.029
determination of adult lifespanGO:000834020.029
purine ribonucleoside catabolic processGO:00461303980.028
negative regulation of protein metabolic processGO:00512483910.028
positive regulation of membrane protein ectodomain proteolysisGO:0051044130.028
melanin metabolic processGO:000658210.028
cell adhesionGO:00071553250.028
regulation of nucleotide metabolic processGO:00061402690.028
regulation of cytokine productionGO:00018172320.027
regulation of secretion by cellGO:19035301770.027
actin filament organizationGO:00070151280.027
mapk cascadeGO:00001652880.027
oxidation reduction processGO:00551143960.027
small gtpase mediated signal transductionGO:0007264780.027
regulation of cell morphogenesisGO:00226041530.027
membrane raft organizationGO:0031579100.026
negative regulation of immune system processGO:00026831360.026
Human
regulation of natural killer cell proliferationGO:003281740.026
Human
organic hydroxy compound metabolic processGO:19016151470.026
single organism cellular localizationGO:19025803320.026
positive regulation of cellular catabolic processGO:00313312840.026
intracellular protein transportGO:00068862700.025
regulation of protein kinase activityGO:00458592890.025
mitotic cell cycle processGO:19030472860.025
rab protein signal transductionGO:003248240.025
single organismal cell cell adhesionGO:00163371480.025
membrane assemblyGO:0071709100.024
negative regulation of cell deathGO:00605483450.024
regulation of small gtpase mediated signal transductionGO:00510561560.024
cell projection organizationGO:00300302520.024
response to salt stressGO:000965130.024
membrane biogenesisGO:0044091130.023
regulation of ras protein signal transductionGO:00465781550.023
regulation of multi organism processGO:00439001570.023
immune responseGO:00069553070.023
regulation of cellular amino acid metabolic processGO:000652160.023
negative regulation of synaptic transmissionGO:005080520.023
metal ion transportGO:00300012720.023
protein modification by small protein conjugationGO:00324463420.023
cellular protein complex assemblyGO:00436231880.023
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
positive regulation of protein kinase activityGO:00458601900.022
cardiovascular system developmentGO:00723582620.022
actin filament based movementGO:0030048170.022
defense responseGO:00069523150.021
regulation of gtpase activityGO:00430871800.021
response to organonitrogen compoundGO:00102431560.021
actin filament based processGO:00300292240.021
positive regulation of cytokine productionGO:00018191670.021
lipid catabolic processGO:0016042840.021
ion transmembrane transportGO:00342203380.021
memoryGO:000761330.021
response to nitrogen compoundGO:19016981840.020
cytokine secretionGO:0050663640.020
maintenance of locationGO:00512351120.020
stress activated mapk cascadeGO:0051403930.020
cellular response to abiotic stimulusGO:00712141170.020
endomembrane system organizationGO:00102561960.020
ribonucleoside monophosphate metabolic processGO:00091611870.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
single organism carbohydrate metabolic processGO:00447231930.020
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.020
developmental programmed cell deathGO:001062330.019
locomotory behaviorGO:000762610.019
negative regulation of protein transportGO:0051224750.019
endosomal transportGO:00161971290.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
nervous system developmentGO:00073992930.019
spermatid differentiationGO:004851540.019
neurological system processGO:00508771630.019
negative regulation of cell cycleGO:00457861930.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
negative regulation of protein maturationGO:19033181420.019
circulatory system processGO:00030131130.019
regulation of leukocyte activationGO:00026941150.019
Human
ribonucleotide catabolic processGO:00092614050.019
hemopoiesisGO:00300971800.019
cell cycle phase transitionGO:00447701730.018
positive regulation of secretionGO:00510471160.018
syncytium formation by plasma membrane fusionGO:000076820.018
positive regulation of secretion by cellGO:19035321080.018
compound eye developmentGO:004874910.018
regulation of synaptic plasticityGO:004816730.018
nucleotide catabolic processGO:00091664080.018
negative regulation of hydrolase activityGO:00513461820.018
epithelial cell migrationGO:00106311190.018
segmentationGO:003528240.018
nucleoside monophosphate metabolic processGO:00091231910.018
angiogenesisGO:00015251470.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
blood circulationGO:00080151130.017
anion transportGO:00068201610.017
cell cycle g1 s phase transitionGO:0044843800.017
peptidyl tyrosine modificationGO:00182121700.017
myoblast fusionGO:000752010.017
regulation of intracellular protein transportGO:00331571230.017
positive regulation of rab gtpase activityGO:0032851390.017
positive regulation of nucleotide catabolic processGO:00308131850.017
growthGO:00400072020.017
blastoderm segmentationGO:000735020.017
covalent chromatin modificationGO:00165692540.017
chromatin modificationGO:00165682980.017
chemical homeostasisGO:00488783060.017
regulation of system processGO:00440571010.017
response to woundingGO:00096111680.017
regulation of rho gtpase activityGO:0032319660.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
lipid biosynthetic processGO:00086101770.017
positive regulation of cell adhesionGO:0045785840.017
oocyte differentiationGO:000999420.017
cellular response to dna damage stimulusGO:00069743790.017
positive regulation of organelle organizationGO:00106381950.017
natural killer cell activationGO:0030101120.016
Human
protein targetingGO:00066051870.016
regulation of cell cycle phase transitionGO:19019871260.016
regulation of mitotic cell cycleGO:00073461890.016
vesicle organizationGO:0016050620.016
cellular response to nitrogen compoundGO:19016991440.016
regulation of homeostatic processGO:00328441210.016
organonitrogen compound biosynthetic processGO:19015662000.016
positive regulation of apoptotic processGO:00430652460.016
epithelium developmentGO:00604292270.016
regulation of cell cell adhesionGO:0022407570.016
nucleocytoplasmic transportGO:00069131760.016
generation of neuronsGO:00486991520.016
cellular lipid catabolic processGO:0044242650.016
atp metabolic processGO:00460341760.016
regulation of protein secretionGO:0050708860.016
natural killer cell proliferationGO:000178740.016
Human
oocyte developmentGO:004859910.016
cation transportGO:00068123310.016
morphogenesis of embryonic epitheliumGO:001633140.016
blood vessel developmentGO:00015681720.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
positive regulation of immune responseGO:00507781590.015
Human
gtp metabolic processGO:00460392390.015
immune effector processGO:00022521590.015
regulation of cellular response to stressGO:00801352440.015
associative learningGO:000830610.015
negative regulation of apoptotic processGO:00430663160.015
tumor necrosis factor productionGO:0032640430.015
negative regulation of transportGO:00510511760.015
cellular component morphogenesisGO:00329893140.015
cell morphogenesisGO:00009022960.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
sensory perception of smellGO:000760820.015
positive regulation of rho gtpase activityGO:0032321560.015
cell projection morphogenesisGO:00488581290.015
protein secretionGO:0009306980.015
regulation of tumor necrosis factor productionGO:0032680430.015
negative regulation of organelle organizationGO:00106391260.015
negative regulation of intracellular signal transductionGO:19025321830.015
hindbrain developmentGO:003090230.015
regulation of cell cycle processGO:00105642660.015
regulation of mitochondrion organizationGO:0010821540.015
signal transduction by phosphorylationGO:00230142970.015
mononuclear cell proliferationGO:0032943710.015
Human
reactive oxygen species metabolic processGO:0072593750.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
cellular macromolecule catabolic processGO:00442653800.015
regulation of nucleocytoplasmic transportGO:0046822980.015
regulation of hormone levelsGO:00108171250.014
heterotypic cell cell adhesionGO:0034113280.014
inorganic ion transmembrane transportGO:00986602310.014
positive regulation of ras gtpase activityGO:00323201170.014
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.014
organophosphate biosynthetic processGO:00904071630.014
chromatin organizationGO:00063253510.014
regulation of nervous system developmentGO:0051960880.014
positive regulation of synaptic transmissionGO:005080640.014
posttranscriptional regulation of gene expressionGO:00106082130.014
monocarboxylic acid metabolic processGO:00327871850.014
leukocyte differentiationGO:0002521980.014
multi organism cellular processGO:00447641560.014
nitrogen compound transportGO:00717051910.014
response to axon injuryGO:004867810.014
protein ubiquitinationGO:00165673140.014
regulation of cellular ketone metabolic processGO:0010565500.014
cell morphogenesis involved in differentiationGO:00009041440.014
purine ribonucleotide catabolic processGO:00091544040.014
regulation of establishment of protein localizationGO:00702012420.014
protein maturationGO:00516042330.014
peripheral nervous system developmentGO:000742220.014
glycerolipid metabolic processGO:00464861070.014
cytoplasmic transportGO:00164823790.014
regulation of cell cycleGO:00517263930.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
cellular macromolecular complex assemblyGO:00346223240.014
cellular response to hormone stimulusGO:00328701250.014
regulation of cell motilityGO:20001452990.014
anterior posterior axis specificationGO:000994820.014
response to cytokineGO:00340972320.013
protein acylationGO:00435431380.013
calcium ion transportGO:00068161470.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
circulatory system developmentGO:00723592620.013
wound healingGO:00420601150.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
cellular protein catabolic processGO:00442572610.013
chemotaxisGO:00069351570.013
divalent metal ion transportGO:00708381520.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
immune response regulating signaling pathwayGO:0002764970.013
Human
negative regulation of protein phosphorylationGO:00019331400.013
positive regulation of immune system processGO:00026842830.013
Human
cellular response to external stimulusGO:00714961110.013
regulation of mapk cascadeGO:00434082620.013
histone modificationGO:00165702510.013
leukocyte proliferationGO:0070661740.013
Human
response to external biotic stimulusGO:00432072610.013
cell growthGO:00160491600.013
spermatid developmentGO:000728640.013
gtp catabolic processGO:00061842370.013
multicellular organismal homeostasisGO:0048871670.013
neurogenesisGO:00220081690.013
small molecule biosynthetic processGO:00442831570.013
epithelial cell differentiationGO:00308551410.013
adult locomotory behaviorGO:000834410.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
cation transmembrane transportGO:00986552380.013
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of intracellular transportGO:00323861950.012
viral life cycleGO:00190581320.012
photoreceptor cell differentiationGO:004653020.012
establishment of protein localization to membraneGO:00901501210.012
anatomical structure homeostasisGO:00602491000.012
cellular response to growth factor stimulusGO:00713631970.012
regulation of vesicle mediated transportGO:00606271300.012
negative regulation of cell cycle processGO:00109481210.012
circadian behaviorGO:004851220.012
activation of immune responseGO:00022531140.012
Human
cellular response to organonitrogen compoundGO:00714171240.012
cell cell signalingGO:00072671550.012
mitotic cell cycleGO:00002783260.012
rhythmic behaviorGO:000762220.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
regulation of body fluid levelsGO:0050878990.012
rho protein signal transductionGO:0007266260.012
establishment of protein localization to organelleGO:00725941720.012
regulation of dna metabolic processGO:00510521530.012
monovalent inorganic cation transportGO:00156721280.012
membrane lipid metabolic processGO:0006643530.012
endocytosisGO:00068971590.012
viral processGO:00160321460.012
ameboidal type cell migrationGO:00016671350.012
reactive oxygen species biosynthetic processGO:190340940.012
inorganic cation transmembrane transportGO:00986621940.012
carbohydrate derivative biosynthetic processGO:19011372070.012
interspecies interaction between organismsGO:00444191560.012
anterior posterior axis specification embryoGO:000859520.012
regulation of ion transportGO:00432691890.012
organ formationGO:004864530.012
cellular ketone metabolic processGO:0042180800.012
regulation of membrane protein ectodomain proteolysisGO:0051043170.012
positive regulation of intracellular protein transportGO:0090316760.012
cellular cation homeostasisGO:00300031630.012
regulation of mononuclear cell proliferationGO:0032944650.012
Human
regulation of growthGO:00400081650.012
regulation of response to external stimulusGO:00321012220.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
cellular metal ion homeostasisGO:00068751460.012
myeloid cell differentiationGO:00300991170.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
rac protein signal transductionGO:0016601120.012
negative regulation of cell proliferationGO:00082852280.012
phospholipid metabolic processGO:0006644990.012
protein localization to membraneGO:00726571600.012
erk1 and erk2 cascadeGO:00703711040.012
g1 s transition of mitotic cell cycleGO:0000082780.011
alcohol metabolic processGO:00060661140.011
epithelium migrationGO:00901321190.011
response to organic cyclic compoundGO:00140702040.011
cellular carbohydrate metabolic processGO:0044262840.011
t cell activationGO:0042110990.011
Human
regulation of metal ion transportGO:00109591200.011
negative regulation of phosphatase activityGO:0010923610.011
lymphocyte proliferationGO:0046651700.011
Human
metencephalon developmentGO:002203720.011
female gamete generationGO:000729220.011
cellular response to organic cyclic compoundGO:00714071270.011
cellular response to oxygen containing compoundGO:19017012760.011
response to inorganic substanceGO:00100351270.011
peptidyl lysine modificationGO:00182051440.011
golgi vesicle transportGO:0048193800.011
tumor necrosis factor superfamily cytokine productionGO:0071706450.011
positive regulation of interleukin 8 productionGO:0032757360.011
negative regulation of mitotic cell cycle phase transitionGO:1901991850.011
muscle contractionGO:0006936730.011
positive regulation of phosphorylationGO:00423273940.011
tripartite regional subdivisionGO:000735120.011
regulation of purine nucleotide catabolic processGO:00331212050.011
negative regulation of cytoplasmic transportGO:1903650460.011
ribonucleoside catabolic processGO:00424544060.011
regulation of protein polymerizationGO:0032271630.011
carboxylic acid biosynthetic processGO:0046394970.011
proteasomal protein catabolic processGO:00104981760.011
regulation of transmembrane transporter activityGO:0022898740.011
negative regulation of intracellular transportGO:0032387600.011
neuron projection regenerationGO:003110210.011
negative regulation of secretion by cellGO:1903531520.011
mitochondrion organizationGO:00070051560.011
regulation of cytoplasmic transportGO:19036491490.011
immune system developmentGO:00025201950.011
negative regulation of t cell receptor signaling pathwayGO:005086040.011
Human
protein autophosphorylationGO:00467771230.011
negative regulation of transferase activityGO:00513481240.011
negative regulation of mitotic cell cycleGO:00459301020.011
sequestering of calcium ionGO:0051208170.011
hormone secretionGO:0046879650.011
negative regulation of cell differentiationGO:00455961710.011
regulation of protein serine threonine kinase activityGO:00719001790.011
positive regulation of kinase activityGO:00336742040.011
thymus developmentGO:004853830.011
inner ear morphogenesisGO:004247240.011
regulation of meiotic cell cycleGO:005144540.010
atp catabolic processGO:00062001570.010
organic acid biosynthetic processGO:0016053970.010
amide transportGO:0042886760.010
response to radiationGO:00093141510.010
ion homeostasisGO:00508012300.010
cell projection assemblyGO:00300311260.010
leukocyte chemotaxisGO:0030595760.010
negative regulation of developmental processGO:00510932470.010
negative regulation of proteolysisGO:00458611320.010
dna repairGO:00062811980.010
behavioral response to ethanolGO:004814920.010
cerebellum developmentGO:002154920.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
post embryonic organ developmentGO:004856910.010
carboxylic acid catabolic processGO:0046395710.010
peptide transportGO:0015833740.010
hormone transportGO:0009914680.010
heart processGO:0003015620.010
secretionGO:00469032540.010
neuron differentiationGO:00301821380.010
ubiquitin dependent protein catabolic processGO:00065112060.010
microtubule cytoskeleton organizationGO:00002261760.010
cell type specific apoptotic processGO:00972851250.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
negative regulation of locomotionGO:00400131180.010
nucleus localizationGO:005164710.010
positive regulation of cell proliferationGO:00082843010.010
regulation of erk1 and erk2 cascadeGO:0070372990.010
hemostasisGO:0007599760.010
negative regulation of cell migrationGO:00303361020.010

PTPN18 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.102
Human
disease of metabolismDOID:00146672950.057
Human
disease of cellular proliferationDOID:145661740.045
Human
musculoskeletal system diseaseDOID:172230.028
Human
organ system cancerDOID:00506861640.027
Human
cancerDOID:1621670.027
Human
connective tissue diseaseDOID:651090.027
Human
inherited metabolic disorderDOID:6552420.022
nervous system diseaseDOID:8634310.020
central nervous system diseaseDOID:3311860.020
sensory system diseaseDOID:00501552030.019
hypersensitivity reaction diseaseDOID:0060056250.017
Human
bone diseaseDOID:0080001880.015
Human
hemorrhagic diseaseDOID:2213100.015
blood platelet diseaseDOID:2218100.015
blood coagulation diseaseDOID:1247210.015
hematopoietic system diseaseDOID:741000.015
acquired metabolic diseaseDOID:0060158580.012
Human
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
muscular diseaseDOID:00800001140.011
muscle tissue diseaseDOID:661130.011
myopathyDOID:4231040.011