Homo sapiens

0 known processes

PARP8

poly (ADP-ribose) polymerase family, member 8

(Aliases: pART16,MGC42864,FLJ21308)

PARP8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide catabolic processGO:00091664080.066
post embryonic developmentGO:000979120.064
ion transmembrane transportGO:00342203380.060
purine containing compound catabolic processGO:00725234110.057
purine ribonucleoside metabolic processGO:00461284370.055
immune responseGO:00069553070.052
purine nucleoside triphosphate metabolic processGO:00091444120.052
ribonucleoside triphosphate catabolic processGO:00092033910.052
purine nucleoside catabolic processGO:00061523980.052
ribonucleoside triphosphate metabolic processGO:00091994120.051
positive regulation of catabolic processGO:00098963100.050
nucleoside phosphate catabolic processGO:19012924120.049
nucleoside triphosphate metabolic processGO:00091414220.048
transmembrane transportGO:00550853990.047
amine metabolic processGO:0009308440.047
nucleoside catabolic processGO:00091644080.047
defense responseGO:00069523150.047
positive regulation of cellular catabolic processGO:00313312840.046
purine nucleotide catabolic processGO:00061954050.046
purine ribonucleotide catabolic processGO:00091544040.046
purine ribonucleoside catabolic processGO:00461303980.046
regulation of cellular amino acid metabolic processGO:000652160.045
positive regulation of transportGO:00510503360.045
ribonucleotide catabolic processGO:00092614050.045
nucleoside triphosphate catabolic processGO:00091433940.044
cellular ketone metabolic processGO:0042180800.044
regulation of cellular amine metabolic processGO:0033238110.044
glycosyl compound catabolic processGO:19016584130.043
cellular amine metabolic processGO:0044106410.042
multicellular organismal agingGO:001025930.042
purine ribonucleoside triphosphate catabolic processGO:00092073910.042
purine nucleoside triphosphate catabolic processGO:00091463920.042
female gamete generationGO:000729220.041
organophosphate catabolic processGO:00464344300.041
ribonucleoside catabolic processGO:00424544060.041
positive regulation of hydrolase activityGO:00513453310.040
Human
innate immune responseGO:00450871780.040
cellular amino acid metabolic processGO:00065201160.040
ras protein signal transductionGO:0007265730.040
response to external biotic stimulusGO:00432072610.039
cytoplasmic transportGO:00164823790.039
determination of adult lifespanGO:000834020.039
regulation of cell cycleGO:00517263930.039
small gtpase mediated signal transductionGO:0007264780.039
gtp metabolic processGO:00460392390.038
positive regulation of purine nucleotide metabolic processGO:19005442270.038
cytokine productionGO:00018162470.038
oogenesisGO:004847720.037
regulation of nucleotide metabolic processGO:00061402690.036
regulation of protein localizationGO:00328802960.036
positive regulation of phosphorylationGO:00423273940.036
Human
guanosine containing compound metabolic processGO:19010682440.035
regulation of establishment of protein localizationGO:00702012420.035
regulation of cellular ketone metabolic processGO:0010565500.035
positive regulation of immune system processGO:00026842830.034
negative regulation of protein metabolic processGO:00512483910.034
positive regulation of cytokine productionGO:00018191670.034
positive regulation of nucleotide metabolic processGO:00459812300.034
response to biotic stimulusGO:00096072760.033
cellular macromolecule catabolic processGO:00442653800.033
response to oxygen containing compoundGO:19017003690.033
guanosine containing compound catabolic processGO:19010692390.033
regulation of immune responseGO:00507762010.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
positive regulation of cellular component organizationGO:00511303760.033
system processGO:00030083490.033
locomotory behaviorGO:000762610.032
negative regulation of catalytic activityGO:00430863350.032
regulation of nucleotide catabolic processGO:00308112050.032
cation transportGO:00068123310.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
rho protein signal transductionGO:0007266260.031
positive regulation of cell deathGO:00109422630.031
secretionGO:00469032540.031
positive regulation of immune responseGO:00507781590.030
response to abiotic stimulusGO:00096283360.030
regulation of purine nucleotide metabolic processGO:19005422640.030
lipid metabolic processGO:00066293810.030
cell adhesionGO:00071553250.030
negative regulation of phosphate metabolic processGO:00459362670.030
positive regulation of cellular amine metabolic processGO:003324070.030
regulation of gtp catabolic processGO:00331241800.029
negative regulation of cellular protein metabolic processGO:00322693530.029
gtp catabolic processGO:00061842370.029
immune response activating signal transductionGO:0002757900.029
actin filament based processGO:00300292240.029
regulation of protein transportGO:00512232130.029
regulation of response to external stimulusGO:00321012220.029
response to other organismGO:00517072610.029
regulation of proteolysisGO:00301622930.029
activation of immune responseGO:00022531140.028
nervous system developmentGO:00073992930.028
positive regulation of nucleotide catabolic processGO:00308131850.028
biological adhesionGO:00226103310.028
regulation of nucleoside metabolic processGO:00091182090.028
regulation of cytokine productionGO:00018172320.027
cellular lipid metabolic processGO:00442553030.027
negative regulation of phosphorus metabolic processGO:00105632670.027
regulation of cell differentiationGO:00455953930.027
positive regulation of programmed cell deathGO:00430682490.027
regulation of purine nucleotide catabolic processGO:00331212050.027
vesicle mediated transportGO:00161923710.026
secretion by cellGO:00329402260.026
positive regulation of defense responseGO:0031349870.026
cell projection organizationGO:00300302520.026
positive regulation of purine nucleotide catabolic processGO:00331231850.026
cell morphogenesisGO:00009022960.026
response to cytokineGO:00340972320.026
positive regulation of nucleoside metabolic processGO:00459791860.026
protein maturationGO:00516042330.026
metal ion transportGO:00300012720.026
regulation of gtpase activityGO:00430871800.026
regulation of cellular component movementGO:00512703340.026
immune effector processGO:00022521590.025
single organism cellular localizationGO:19025803320.025
intracellular protein transportGO:00068862700.025
response to virusGO:00096151260.025
positive regulation of gtpase activityGO:00435471660.025
segmentationGO:003528240.025
cellular response to oxygen containing compoundGO:19017012760.025
dephosphorylationGO:00163112090.024
positive regulation of apoptotic processGO:00430652460.024
positive regulation of protein phosphorylationGO:00019343130.024
Human
negative regulation of programmed cell deathGO:00430693210.024
cellular component morphogenesisGO:00329893140.024
regulation of cell cycle processGO:00105642660.024
regulation of cellular component biogenesisGO:00440872810.024
regulation of kinase activityGO:00435493140.023
Human
cell developmentGO:00484683280.023
neuromuscular junction developmentGO:000752830.023
mapk cascadeGO:00001652880.023
positive regulation of gtp catabolic processGO:00331261660.023
mitotic cell cycleGO:00002783260.023
protein catabolic processGO:00301633250.022
signal transduction by phosphorylationGO:00230142970.022
regulation of protein kinase activityGO:00458592890.022
Human
protein localization to organelleGO:00333652800.022
lymphocyte activationGO:00466491330.022
negative regulation of apoptotic processGO:00430663160.022
negative regulation of multicellular organismal processGO:00512413170.022
single organism membrane organizationGO:00448022680.022
cation transmembrane transportGO:00986552380.022
regulation of small gtpase mediated signal transductionGO:00510561560.022
immune response regulating signaling pathwayGO:0002764970.021
leukocyte activationGO:00453211640.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
regulation of secretionGO:00510461940.021
anion transportGO:00068201610.021
regulation of locomotionGO:00400123290.021
negative regulation of cell proliferationGO:00082852280.021
cell activationGO:00017752130.021
regulation of intracellular transportGO:00323861950.021
cellular response to dna damage stimulusGO:00069743790.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
inorganic ion transmembrane transportGO:00986602310.021
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of hydrolase activityGO:00513461820.021
carbohydrate derivative biosynthetic processGO:19011372070.021
Human
protein processingGO:00164852260.021
memoryGO:000761330.020
regulation of transferase activityGO:00513383550.020
Human
protein targetingGO:00066051870.020
organic anion transportGO:00157111030.020
ion homeostasisGO:00508012300.020
chemical homeostasisGO:00488783060.020
protein ubiquitinationGO:00165673140.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
cellular protein catabolic processGO:00442572610.020
cellular response to endogenous stimulusGO:00714953360.020
organonitrogen compound biosynthetic processGO:19015662000.020
regenerationGO:003109940.020
membrane organizationGO:00610242920.020
mitotic cell cycle processGO:19030472860.020
negative regulation of phosphorylationGO:00423261740.020
inorganic cation transmembrane transportGO:00986621940.019
cardiac muscle cell contractionGO:008600340.019
regulation of multi organism processGO:00439001570.019
hemopoiesisGO:00300971800.019
immune system developmentGO:00025201950.019
regulation of cellular response to stressGO:00801352440.019
motor neuron axon guidanceGO:000804520.019
positive regulation of developmental processGO:00510943140.019
epithelium developmentGO:00604292270.019
maintenance of locationGO:00512351120.019
carbohydrate metabolic processGO:00059752070.019
Human
negative regulation of cell deathGO:00605483450.019
Human
positive regulation of protein transportGO:00512221350.019
cellular homeostasisGO:00197251960.019
positive regulation of innate immune responseGO:0045089790.019
regulation of anatomical structure morphogenesisGO:00226032860.019
negative regulation of intracellular signal transductionGO:19025321830.019
nucleocytoplasmic transportGO:00069131760.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
protein modification by small protein conjugationGO:00324463420.019
nitrogen compound transportGO:00717051910.019
calcium ion transportGO:00068161470.019
regulation of ras protein signal transductionGO:00465781550.018
negative regulation of cellular component organizationGO:00511292350.018
response to nitrogen compoundGO:19016981840.018
negative regulation of cellular amine metabolic processGO:003323930.018
negative regulation of protein modification processGO:00314002000.018
regulation of ras gtpase activityGO:00323181280.018
negative regulation of developmental processGO:00510932470.018
reactive oxygen species metabolic processGO:0072593750.018
divalent metal ion transportGO:00708381520.018
activation of innate immune responseGO:0002218550.018
spermatid developmentGO:000728640.018
response to lipidGO:00339932060.018
regulation of mapk cascadeGO:00434082620.018
hindbrain developmentGO:003090230.018
response to organic cyclic compoundGO:00140702040.017
negative regulation of cell cycleGO:00457861930.017
i kappab kinase nf kappab signalingGO:00072491660.017
regulation of leukocyte activationGO:00026941150.017
nuclear transportGO:00511691790.017
lipid biosynthetic processGO:00086101770.017
regulation of endopeptidase activityGO:00525481700.017
spermatid differentiationGO:004851540.017
regulation of defense responseGO:00313471540.017
regulation of protein processingGO:00706131500.017
actin cytoskeleton organizationGO:00300362070.017
regulation of protein serine threonine kinase activityGO:00719001790.017
Human
divalent inorganic cation transportGO:00725111580.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of mitotic cell cycleGO:00073461890.017
muscle system processGO:0003012810.017
reactive oxygen species biosynthetic processGO:190340940.017
defense response to other organismGO:00985421290.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
regulation of innate immune responseGO:0045088970.016
blastoderm segmentationGO:000735020.016
neurogenesisGO:00220081690.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
microtubule based processGO:00070172100.016
g protein coupled receptor signaling pathwayGO:00071862070.016
actin filament based movementGO:0030048170.016
chromatin organizationGO:00063253510.016
single organism carbohydrate metabolic processGO:00447231930.016
Human
establishment of protein localization to organelleGO:00725941720.016
regulation of ion transportGO:00432691890.016
peripheral nervous system developmentGO:000742220.016
chemotaxisGO:00069351570.016
positive regulation of ras gtpase activityGO:00323201170.016
compound eye developmentGO:004874910.016
regulation of protein maturationGO:19033171500.016
regulation of cytoplasmic transportGO:19036491490.016
adult locomotory behaviorGO:000834410.015
nerve developmentGO:002167540.015
neuroblast proliferationGO:000740540.015
apoptotic signaling pathwayGO:00971902680.015
negative regulation of transportGO:00510511760.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
oocyte developmentGO:004859910.015
cellular response to lipidGO:00713961270.015
regulation of synaptic plasticityGO:004816730.015
defense response to virusGO:0051607710.015
covalent chromatin modificationGO:00165692540.015
cellular chemical homeostasisGO:00550821800.015
histone modificationGO:00165702510.015
regulation of cell motilityGO:20001452990.015
rhythmic behaviorGO:000762220.015
matingGO:000761810.015
endomembrane system organizationGO:00102561960.015
organelle assemblyGO:00709251760.015
organophosphate biosynthetic processGO:00904071630.015
negative regulation of protein maturationGO:19033181420.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
regulation of cytoskeleton organizationGO:00514931770.015
regulation of secretion by cellGO:19035301770.015
positive regulation of secretionGO:00510471160.015
cell growthGO:00160491600.015
morphogenesis of embryonic epitheliumGO:001633140.015
oocyte differentiationGO:000999420.015
positive regulation of cell differentiationGO:00455972110.015
regulation of peptidase activityGO:00525471800.015
regulation of protein catabolic processGO:00421761550.015
negative regulation of protein phosphorylationGO:00019331400.014
posttranscriptional regulation of gene expressionGO:00106082130.014
modification dependent macromolecule catabolic processGO:00436322120.014
endosomal transportGO:00161971290.014
positive regulation of kinase activityGO:00336742040.014
Human
multi organism cellular processGO:00447641560.014
regulation of cell migrationGO:00303342890.014
circadian behaviorGO:004851220.014
positive regulation of secretion by cellGO:19035321080.014
glycoprotein metabolic processGO:00091001100.014
Human
regulation of reactive oxygen species biosynthetic processGO:190342630.014
cellular ion homeostasisGO:00068731680.014
cellular protein complex assemblyGO:00436231880.014
regulation of lymphocyte activationGO:00512491030.014
cellular response to cytokine stimulusGO:00713451810.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
regulation of actin filament based processGO:00329701410.014
proteasomal protein catabolic processGO:00104981760.014
oxidation reduction processGO:00551143960.014
cellular response to abiotic stimulusGO:00712141170.014
taxisGO:00423301570.014
actin mediated cell contractionGO:0070252120.014
regulation of intracellular protein transportGO:00331571230.014
growthGO:00400072020.014
blood vessel developmentGO:00015681720.014
protein secretionGO:0009306980.014
positive regulation of transferase activityGO:00513472270.014
Human
sequestering of metal ionGO:0051238240.014
reactive nitrogen species metabolic processGO:200105730.014
epithelial cell differentiationGO:00308551410.014
striated muscle contractionGO:0006941520.014
positive regulation of cell proliferationGO:00082843010.014
neurological system processGO:00508771630.014
response to organonitrogen compoundGO:00102431560.014
regulation of cell adhesionGO:00301551660.014
rna processingGO:00063962550.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
muscle contractionGO:0006936730.014
small molecule biosynthetic processGO:00442831570.014
carboxylic acid transportGO:0046942630.014
cell part morphogenesisGO:00329901370.013
cellular metal ion homeostasisGO:00068751460.013
cellular response to external stimulusGO:00714961110.013
sequestering of calcium ionGO:0051208170.013
mitotic cell cycle phase transitionGO:00447721620.013
protein oligomerizationGO:00512591730.013
regulation of bindingGO:00510981110.013
positive regulation of cell migrationGO:00303351720.013
endocytosisGO:00068971590.013
protein localization to nucleusGO:00345041360.013
ubiquitin dependent protein catabolic processGO:00065112060.013
positive regulation of synaptic transmissionGO:005080640.013
associative learningGO:000830610.013
chromatin modificationGO:00165682980.013
cation homeostasisGO:00550801890.013
cell divisionGO:00513011680.013
negative regulation of proteolysisGO:00458611320.013
response to hormoneGO:00097251750.013
negative regulation of immune system processGO:00026831360.013
neurotransmitter secretionGO:000726940.013
anterior posterior axis specificationGO:000994820.013
metencephalon developmentGO:002203720.013
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
central nervous system developmentGO:00074171230.013
modification dependent protein catabolic processGO:00199412090.013
neuron differentiationGO:00301821380.013
regulation of cell activationGO:00508651250.013
cardiovascular system developmentGO:00723582620.013
anion transmembrane transportGO:0098656760.013
negative regulation of transferase activityGO:00513481240.013
cellular cation homeostasisGO:00300031630.013
rna interferenceGO:001624640.013
protein localization to membraneGO:00726571600.013
positive regulation of organelle organizationGO:00106381950.013
interspecies interaction between organismsGO:00444191560.013
rab protein signal transductionGO:003248240.013
positive regulation of proteolysisGO:00458621420.013
response to woundingGO:00096111680.013
embryonic epithelial tube formationGO:000183840.013
response to radiationGO:00093141510.013
inner ear morphogenesisGO:004247240.013
cell projection morphogenesisGO:00488581290.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
cell cycle phase transitionGO:00447701730.012
cardiac muscle contractionGO:0060048340.012
actin filament organizationGO:00070151280.012
autophagyGO:0006914880.012
circulatory system developmentGO:00723592620.012
pattern recognition receptor signaling pathwayGO:0002221480.012
regulation of protein secretionGO:0050708860.012
organic hydroxy compound metabolic processGO:19016151470.012
positive regulation of mapk cascadeGO:00434101900.012
generation of neuronsGO:00486991520.012
wnt signaling pathwayGO:00160551560.012
metal ion homeostasisGO:00550651690.012
regulation of apoptotic signaling pathwayGO:20012331750.012
monocarboxylic acid metabolic processGO:00327871850.012
positive regulation of cellular component biogenesisGO:00440891580.012
regulation of neural precursor cell proliferationGO:200017740.012
regulation of meiotic cell cycleGO:005144540.012
syncytium formation by plasma membrane fusionGO:000076820.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
positive regulation of locomotionGO:00400171860.012
positive regulation of nf kappab transcription factor activityGO:0051092810.012
melanin metabolic processGO:000658210.012
regulation of rho protein signal transductionGO:0035023790.012
innate immune response activating signal transductionGO:0002758480.012
detection of stimulusGO:0051606850.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of vesicle mediated transportGO:00606271300.012
protein importGO:00170381300.012
divalent inorganic cation homeostasisGO:00725071360.012
nuclear importGO:00511701060.012
positive regulation of intracellular transportGO:00323881040.012
positive regulation of peptidase activityGO:0010952880.012
regulation of immune effector processGO:0002697910.012
cell projection assemblyGO:00300311260.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
regulation of transporter activityGO:0032409820.012
photoreceptor cell differentiationGO:004653020.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
regulation of protein complex assemblyGO:00432541470.011
neuron developmentGO:00486661130.011
positive regulation of cell cycleGO:00457871400.011
positive regulation of cellular component movementGO:00512721810.011
microtubule cytoskeleton organizationGO:00002261760.011
tissue regenerationGO:004224630.011
organic acid transportGO:0015849650.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
cell fate determinationGO:000170930.011
positive regulation of protein kinase activityGO:00458601900.011
Human
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
protein import into nucleusGO:00066061040.011
visual behaviorGO:000763220.011
regulation of cell morphogenesisGO:00226041530.011
regulation of growthGO:00400081650.011
cellular response to organonitrogen compoundGO:00714171240.011
vasculature developmentGO:00019441810.011
response to growth factorGO:00708482050.011
stem cell divisionGO:001714520.011
negative regulation of cell differentiationGO:00455961710.011
negative regulation of endopeptidase activityGO:0010951840.011
t cell differentiation in thymusGO:003307740.011
alcohol metabolic processGO:00060661140.011
cellular response to growth factor stimulusGO:00713631970.011
negative regulation of protein processingGO:00109551420.011
cell chemotaxisGO:00603261120.011
positive regulation of response to external stimulusGO:0032103880.011
regulation of cytokine secretionGO:0050707570.011
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.011
regulation of wnt signaling pathwayGO:00301111230.011
sensory perception of painGO:001923340.011
cytokine secretionGO:0050663640.011
tripartite regional subdivisionGO:000735120.011
negative regulation of cell cycle processGO:00109481210.011
cerebellum developmentGO:002154920.011
negative regulation of organelle organizationGO:00106391260.011
organ formationGO:004864530.011
establishment of protein localization to membraneGO:00901501210.011
protein dephosphorylationGO:0006470810.011
angiogenesisGO:00015251470.011
t cell activationGO:0042110990.011
viral processGO:00160321460.011
protein modification by small protein removalGO:0070646920.011
regulation of cell cycle phase transitionGO:19019871260.011
positive regulation of cell motilityGO:20001471770.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
response to axon injuryGO:004867810.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of transmembrane transportGO:00347621390.011
cellular response to hormone stimulusGO:00328701250.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
cell cell signalingGO:00072671550.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
neural crest cell developmentGO:001403230.011
regulation of cell developmentGO:00602841610.010
protein deubiquitinationGO:0016579790.010
behaviorGO:00076101120.010
regulation of nucleocytoplasmic transportGO:0046822980.010
post embryonic organ developmentGO:004856910.010
myoblast fusionGO:000752010.010
response to fungusGO:000962040.010
neural tube formationGO:000184130.010
developmental programmed cell deathGO:001062330.010
regulation of ion transmembrane transportGO:00347651320.010
calcium ion homeostasisGO:00550741220.010
cellular amide metabolic processGO:0043603690.010
tube closureGO:006060630.010
negative regulation of mitotic cell cycleGO:00459301020.010
protein targeting to nucleusGO:00447441040.010
cytokine mediated signaling pathwayGO:00192211090.010
anterior posterior axis specification embryoGO:000859520.010
viral life cycleGO:00190581320.010
leukocyte differentiationGO:0002521980.010
response to inorganic substanceGO:00100351270.010
single organism cell adhesionGO:00986021790.010
positive regulation of protein serine threonine kinase activityGO:00719021190.010
Human
regulation of cellular protein catabolic processGO:1903362960.010
single organism nuclear importGO:19025931040.010

PARP8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.024
cancerDOID:1621670.024
disease of cellular proliferationDOID:145661740.024
organ system cancerDOID:00506861640.024
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
central nervous system diseaseDOID:3311860.020
musculoskeletal system diseaseDOID:172230.020
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
inherited metabolic disorderDOID:6552420.014
retinal diseaseDOID:56791180.014
neurodegenerative diseaseDOID:12891020.013
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.012
cardiovascular system diseaseDOID:12871060.012
immune system diseaseDOID:29141550.010
retinal degenerationDOID:8466890.010