Homo sapiens

0 known processes

INSL4

insulin-like 4 (placenta)

(Aliases: EPIL,PLACENTIN)

INSL4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308440.111
cellular amino acid metabolic processGO:00065201160.111
cellular amine metabolic processGO:0044106410.101
regulation of cellular amino acid metabolic processGO:000652160.099
positive regulation of cellular amine metabolic processGO:003324070.089
regulation of cellular amine metabolic processGO:0033238110.088
positive regulation of cellular amino acid metabolic processGO:004576430.082
defense responseGO:00069523150.081
immune responseGO:00069553070.078
response to biotic stimulusGO:00096072760.070
negative regulation of multicellular organismal processGO:00512413170.069
post embryonic developmentGO:000979120.068
cellular ketone metabolic processGO:0042180800.067
regulation of cellular ketone metabolic processGO:0010565500.065
response to oxygen containing compoundGO:19017003690.060
cellular response to endogenous stimulusGO:00714953360.057
response to other organismGO:00517072610.053
response to external biotic stimulusGO:00432072610.050
regulation of transferase activityGO:00513383550.049
g protein coupled receptor signaling pathwayGO:00071862070.049
regulation of cytokine productionGO:00018172320.048
transmembrane transportGO:00550853990.047
ion transmembrane transportGO:00342203380.046
regulation of cellular component movementGO:00512703340.046
innate immune responseGO:00450871780.045
positive regulation of developmental processGO:00510943140.045
response to lipidGO:00339932060.045
negative regulation of protein metabolic processGO:00512483910.044
cytokine productionGO:00018162470.043
system processGO:00030083490.043
cation transportGO:00068123310.043
regulation of immune responseGO:00507762010.041
regulation of response to external stimulusGO:00321012220.041
biological adhesionGO:00226103310.041
response to cytokineGO:00340972320.041
response to hormoneGO:00097251750.040
cellular response to oxygen containing compoundGO:19017012760.038
protein processingGO:00164852260.038
peptidyl tyrosine phosphorylationGO:00181081700.038
negative regulation of cell deathGO:00605483450.038
negative regulation of cellular protein metabolic processGO:00322693530.037
chemical homeostasisGO:00488783060.037
positive regulation of cell proliferationGO:00082843010.037
response to organic cyclic compoundGO:00140702040.037
regulation of establishment of protein localizationGO:00702012420.037
regulation of kinase activityGO:00435493140.037
locomotory behaviorGO:000762610.036
positive regulation of cellular component organizationGO:00511303760.035
lipid metabolic processGO:00066293810.035
regulation of protein kinase activityGO:00458592890.035
signal transduction by phosphorylationGO:00230142970.035
multicellular organismal agingGO:001025930.034
positive regulation of phosphorylationGO:00423273940.034
response to organonitrogen compoundGO:00102431560.034
small gtpase mediated signal transductionGO:0007264780.033
negative regulation of apoptotic processGO:00430663160.033
determination of adult lifespanGO:000834020.033
ion homeostasisGO:00508012300.032
regulation of protein localizationGO:00328802960.031
negative regulation of cytokine productionGO:0001818820.031
secretionGO:00469032540.031
mapk cascadeGO:00001652880.031
positive regulation of transferase activityGO:00513472270.030
peptidyl tyrosine modificationGO:00182121700.030
response to bacteriumGO:00096171440.030
regulation of secretionGO:00510461940.030
positive regulation of cytokine productionGO:00018191670.030
response to abiotic stimulusGO:00096283360.030
actin filament based processGO:00300292240.030
negative regulation of programmed cell deathGO:00430693210.030
protein maturationGO:00516042330.030
cell adhesionGO:00071553250.029
vesicle mediated transportGO:00161923710.029
cellular metal ion homeostasisGO:00068751460.029
rho protein signal transductionGO:0007266260.029
female gamete generationGO:000729220.029
cation homeostasisGO:00550801890.028
defense response to other organismGO:00985421290.028
positive regulation of immune responseGO:00507781590.028
negative regulation of catalytic activityGO:00430863350.028
negative regulation of cell proliferationGO:00082852280.027
protein catabolic processGO:00301633250.027
nucleoside triphosphate metabolic processGO:00091414220.027
cellular lipid metabolic processGO:00442553030.027
neuromuscular junction developmentGO:000752830.027
regulation of protein transportGO:00512232130.027
ribonucleotide catabolic processGO:00092614050.027
purine ribonucleoside metabolic processGO:00461284370.027
negative regulation of transportGO:00510511760.027
single organism membrane organizationGO:00448022680.027
cellular chemical homeostasisGO:00550821800.027
divalent inorganic cation transportGO:00725111580.027
secretion by cellGO:00329402260.027
regulation of mapk cascadeGO:00434082620.026
cellular response to cytokine stimulusGO:00713451810.026
ras protein signal transductionGO:0007265730.026
nucleotide catabolic processGO:00091664080.026
regulation of cell motilityGO:20001452990.026
immune effector processGO:00022521590.026
matingGO:000761810.026
lipid biosynthetic processGO:00086101770.026
cellular macromolecular complex assemblyGO:00346223240.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
cellular divalent inorganic cation homeostasisGO:00725031280.025
regulation of cell activationGO:00508651250.025
oogenesisGO:004847720.025
positive regulation of mapk cascadeGO:00434101900.025
negative regulation of immune system processGO:00026831360.025
positive regulation of protein phosphorylationGO:00019343130.025
epithelium migrationGO:00901321190.025
negative regulation of phosphorus metabolic processGO:00105632670.025
regulation of cell differentiationGO:00455953930.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
intracellular protein transportGO:00068862700.024
negative regulation of cellular amine metabolic processGO:003323930.024
regulation of purine nucleotide metabolic processGO:19005422640.024
enzyme linked receptor protein signaling pathwayGO:00071673030.024
cytoplasmic transportGO:00164823790.024
regulation of cellular component biogenesisGO:00440872810.024
positive regulation of hydrolase activityGO:00513453310.024
purine ribonucleotide catabolic processGO:00091544040.024
positive regulation of programmed cell deathGO:00430682490.024
purine containing compound catabolic processGO:00725234110.024
cellular macromolecule catabolic processGO:00442653800.024
response to nitrogen compoundGO:19016981840.024
positive regulation of transportGO:00510503360.024
cell activationGO:00017752130.024
regulation of defense responseGO:00313471540.024
membrane organizationGO:00610242920.023
ribonucleoside catabolic processGO:00424544060.023
calcium ion transportGO:00068161470.023
positive regulation of cell deathGO:00109422630.023
synaptic transmission involved in micturitionGO:006008420.023
regulation of nucleotide metabolic processGO:00061402690.023
protein localization to organelleGO:00333652800.023
single organism cellular localizationGO:19025803320.023
negative regulation of phosphate metabolic processGO:00459362670.023
interspecies interaction between organismsGO:00444191560.022
multi organism cellular processGO:00447641560.022
symbiosis encompassing mutualism through parasitismGO:00444031560.022
purine nucleotide catabolic processGO:00061954050.022
leukocyte activationGO:00453211640.022
regulation of proteolysisGO:00301622930.022
actin mediated cell contractionGO:0070252120.022
maintenance of locationGO:00512351120.022
carbohydrate derivative biosynthetic processGO:19011372070.022
growthGO:00400072020.022
viral processGO:00160321460.022
regulation of cell cycleGO:00517263930.022
metal ion transportGO:00300012720.022
cellular ion homeostasisGO:00068731680.022
segmentationGO:003528240.021
oxidation reduction processGO:00551143960.021
positive regulation of apoptotic processGO:00430652460.021
organophosphate catabolic processGO:00464344300.021
regulation of cellular response to stressGO:00801352440.021
negative regulation of protein modification processGO:00314002000.021
cellular cation homeostasisGO:00300031630.021
divalent metal ion transportGO:00708381520.021
regulation of acetylcholine gated cation channel activityGO:190304810.021
protein modification by small protein conjugationGO:00324463420.021
nitrogen compound transportGO:00717051910.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
regulation of peptidyl tyrosine phosphorylationGO:00507301080.021
regulation of hormone levelsGO:00108171250.021
dephosphorylationGO:00163112090.021
regulation of anatomical structure morphogenesisGO:00226032860.021
positive regulation of protein kinase activityGO:00458601900.021
regulation of intracellular transportGO:00323861950.021
glycosyl compound catabolic processGO:19016584130.021
positive regulation of catabolic processGO:00098963100.021
regulation of multi organism processGO:00439001570.020
regulation of locomotionGO:00400123290.020
positive regulation of nucleotide metabolic processGO:00459812300.020
regulation of immune effector processGO:0002697910.020
divalent inorganic cation homeostasisGO:00725071360.020
viral life cycleGO:00190581320.020
positive regulation of immune system processGO:00026842830.020
regulation of cell cycle processGO:00105642660.020
positive regulation of cellular component movementGO:00512721810.020
positive regulation of kinase activityGO:00336742040.020
associative learningGO:000830610.020
regenerationGO:003109940.020
cellular response to organonitrogen compoundGO:00714171240.020
memoryGO:000761330.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
response to virusGO:00096151260.019
protein oligomerizationGO:00512591730.019
reactive oxygen species metabolic processGO:0072593750.019
activation of immune responseGO:00022531140.019
regulation of cell migrationGO:00303342890.019
positive regulation of organelle organizationGO:00106381950.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
cellular response to growth factor stimulusGO:00713631970.019
cation transmembrane transportGO:00986552380.019
nucleoside triphosphate catabolic processGO:00091433940.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
regulation of transmembrane transportGO:00347621390.019
cytosolic calcium ion homeostasisGO:0051480890.019
regulation of i kappab kinase nf kappab signalingGO:00431221620.019
epithelial cell migrationGO:00106311190.019
single organism cell adhesionGO:00986021790.019
cellular protein catabolic processGO:00442572610.019
cell morphogenesisGO:00009022960.019
positive regulation of cellular catabolic processGO:00313312840.019
positive regulation of cell motilityGO:20001471770.019
positive regulation of cell migrationGO:00303351720.018
regulation of actin filament based processGO:00329701410.018
response to inorganic substanceGO:00100351270.018
tissue migrationGO:00901301190.018
metal ion homeostasisGO:00550651690.018
wnt signaling pathwayGO:00160551560.018
cellular component morphogenesisGO:00329893140.018
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.018
nucleoside catabolic processGO:00091644080.018
purine ribonucleoside catabolic processGO:00461303980.018
cellular protein complex assemblyGO:00436231880.018
cellular response to nitrogen compoundGO:19016991440.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
positive regulation of cellular component biogenesisGO:00440891580.018
positive regulation of locomotionGO:00400171860.018
regulation of protein serine threonine kinase activityGO:00719001790.018
protein targetingGO:00066051870.018
apoptotic signaling pathwayGO:00971902680.018
regulation of growthGO:00400081650.017
response to woundingGO:00096111680.017
regulation of nucleotide catabolic processGO:00308112050.017
chromatin organizationGO:00063253510.017
visual behaviorGO:000763220.017
regulation of lymphocyte activationGO:00512491030.017
regulation of cytoskeleton organizationGO:00514931770.017
regulation of secretion by cellGO:19035301770.017
actin cytoskeleton organizationGO:00300362070.017
regulation of nucleoside metabolic processGO:00091182090.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
regulation of ion transportGO:00432691890.017
mitotic cell cycleGO:00002783260.017
response to radiationGO:00093141510.017
regulation of protein maturationGO:19033171500.017
negative regulation of interleukin 13 secretionGO:200066610.017
regulation of endopeptidase activityGO:00525481700.017
ameboidal type cell migrationGO:00016671350.017
epithelial cell proliferationGO:00506731280.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
hemopoiesisGO:00300971800.017
regulation of cell adhesionGO:00301551660.017
cytokine mediated signaling pathwayGO:00192211090.016
monocarboxylic acid metabolic processGO:00327871850.016
negative regulation of t cell cytokine productionGO:000272540.016
cellular response to organic cyclic compoundGO:00714071270.016
mitotic cell cycle processGO:19030472860.016
protein ubiquitinationGO:00165673140.016
reactive oxygen species biosynthetic processGO:190340940.016
nucleoside phosphate catabolic processGO:19012924120.016
regulation of peptidase activityGO:00525471800.016
cellular homeostasisGO:00197251960.016
negative regulation of intracellular signal transductionGO:19025321830.016
cellular response to dna damage stimulusGO:00069743790.016
guanosine containing compound metabolic processGO:19010682440.016
i kappab kinase nf kappab signalingGO:00072491660.016
regulation of transmembrane transporter activityGO:0022898740.016
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.016
cell growthGO:00160491600.016
posttranscriptional regulation of gene expressionGO:00106082130.016
cell cycle phase transitionGO:00447701730.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of viral processGO:00507921030.016
cellular response to hormone stimulusGO:00328701250.016
regulation of lipid metabolic processGO:0019216960.016
single organismal cell cell adhesionGO:00163371480.016
calcium ion homeostasisGO:00550741220.016
neurological system processGO:00508771630.016
nervous system developmentGO:00073992930.015
positive regulation of nucleoside metabolic processGO:00459791860.015
purine nucleoside catabolic processGO:00061523980.015
inorganic ion transmembrane transportGO:00986602310.015
small molecule biosynthetic processGO:00442831570.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
reactive nitrogen species metabolic processGO:200105730.015
response to fungusGO:000962040.015
negative regulation of protein maturationGO:19033181420.015
positive regulation of cytosolic calcium ion concentrationGO:0007204820.015
regulation of purine nucleotide catabolic processGO:00331212050.015
circulatory system developmentGO:00723592620.015
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of calcium ion transportGO:0051924790.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
response to growth factorGO:00708482050.015
regulation of metal ion transportGO:00109591200.015
regulation of protein catabolic processGO:00421761550.015
negative regulation of protein processingGO:00109551420.015
regulation of actin cytoskeleton organizationGO:00329561160.015
epidermis morphogenesisGO:004873030.015
lymphocyte activationGO:00466491330.015
cell type specific apoptotic processGO:00972851250.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
negative regulation of cellular component organizationGO:00511292350.014
blastoderm segmentationGO:000735020.014
response to steroid hormoneGO:0048545800.014
postsynaptic membrane organizationGO:000194120.014
spermatid differentiationGO:004851540.014
visual learningGO:000854210.014
actin filament organizationGO:00070151280.014
regulation of ion transmembrane transporter activityGO:0032412720.014
regulation of leukocyte activationGO:00026941150.014
regulation of protein processingGO:00706131500.014
negative regulation of developmental processGO:00510932470.014
histone modificationGO:00165702510.014
negative regulation of phosphorylationGO:00423261740.014
positive regulation of response to external stimulusGO:0032103880.014
cell cell signalingGO:00072671550.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
detection of stimulusGO:0051606850.014
ossificationGO:00015031210.014
nuclear transportGO:00511691790.014
cell substrate adhesionGO:00315891320.014
hormone metabolic processGO:0042445610.014
gtp catabolic processGO:00061842370.014
purine ribonucleotide biosynthetic processGO:0009152790.014
nucleocytoplasmic transportGO:00069131760.014
striated muscle contractionGO:0006941520.014
covalent chromatin modificationGO:00165692540.014
inorganic cation transmembrane transportGO:00986621940.014
establishment of protein localization to organelleGO:00725941720.014
regulation of ras protein signal transductionGO:00465781550.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
cell projection organizationGO:00300302520.014
guanosine containing compound catabolic processGO:19010692390.014
chromatin modificationGO:00165682980.014
rhythmic behaviorGO:000762220.013
carbohydrate metabolic processGO:00059752070.013
negative regulation of acetylcholine gated cation channel activityGO:190304910.013
negative regulation of locomotionGO:00400131180.013
tissue regenerationGO:004224630.013
regulation of gtp catabolic processGO:00331241800.013
positive regulation of gtpase activityGO:00435471660.013
protein localization to nucleusGO:00345041360.013
regulation of map kinase activityGO:00434051080.013
generation of neuronsGO:00486991520.013
ribonucleotide biosynthetic processGO:0009260810.013
leukocyte migrationGO:00509001070.013
regulation of epithelial cell proliferationGO:00506781130.013
epithelial cell differentiationGO:00308551410.013
behaviorGO:00076101120.013
syncytium formation by plasma membrane fusionGO:000076820.013
positive regulation of gtp catabolic processGO:00331261660.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
response to molecule of bacterial originGO:0002237820.013
negative regulation of protein phosphorylationGO:00019331400.013
negative regulation of transferase activityGO:00513481240.013
single organism carbohydrate metabolic processGO:00447231930.013
negative regulation of proteolysisGO:00458611320.013
modification dependent macromolecule catabolic processGO:00436322120.013
ubiquitin dependent protein catabolic processGO:00065112060.013
oocyte developmentGO:004859910.013
response to lipopolysaccharideGO:0032496700.013
positive regulation of cell differentiationGO:00455972110.013
regulation of protein complex assemblyGO:00432541470.013
regulation of gtpase activityGO:00430871800.013
regulation of vesicle mediated transportGO:00606271300.013
regulation of protein secretionGO:0050708860.013
regulation of meiotic cell cycleGO:005144540.013
negative regulation of cell differentiationGO:00455961710.012
cell developmentGO:00484683280.012
sequestering of metal ionGO:0051238240.012
organophosphate biosynthetic processGO:00904071630.012
cellular response to lipidGO:00713961270.012
glial cell migrationGO:000834740.012
regulation of ras gtpase activityGO:00323181280.012
t cell activationGO:0042110990.012
response to oxidative stressGO:00069791210.012
positive regulation of peptidyl serine phosphorylation of stat proteinGO:003314130.012
adult locomotory behaviorGO:000834410.012
multicellular organismal signalingGO:0035637340.012
positive regulation of protein transportGO:00512221350.012
immune response regulating signaling pathwayGO:0002764970.012
response to axon injuryGO:004867810.012
endothelial cell migrationGO:0043542860.012
angiogenesisGO:00015251470.012
negative regulation of protein transportGO:0051224750.012
modification dependent protein catabolic processGO:00199412090.012
protein acylationGO:00435431380.012
cellular calcium ion homeostasisGO:00068741170.012
anatomical structure homeostasisGO:00602491000.012
blood circulationGO:00080151130.012
regulation of cell morphogenesisGO:00226041530.012
regulation of t cell activationGO:0050863770.012
sequestering of calcium ionGO:0051208170.012
anterior posterior axis specificationGO:000994820.012
negative regulation of growthGO:0045926970.012
wound healingGO:00420601150.012
regulation of intracellular protein transportGO:00331571230.012
spermatid developmentGO:000728640.012
cellular response to abiotic stimulusGO:00712141170.012
protein localization to membraneGO:00726571600.012
mitotic cell cycle phase transitionGO:00447721620.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
cardiovascular system developmentGO:00723582620.012
protein importGO:00170381300.012
negative regulation of cell migrationGO:00303361020.012
oocyte differentiationGO:000999420.012
negative regulation of protein kinase activityGO:0006469980.012
regulation of bindingGO:00510981110.012
endomembrane system organizationGO:00102561960.012
positive regulation of leukocyte activationGO:0002696800.012
cellular response to external stimulusGO:00714961110.012
positive regulation of cytoskeleton organizationGO:0051495830.012
activation of protein kinase activityGO:0032147900.011
cardiac muscle cell contractionGO:008600340.011
regulation of response to woundingGO:19030341010.011
blood vessel morphogenesisGO:00485141620.011
organ morphogenesisGO:00098871470.011
regulation of epithelial cell migrationGO:0010632930.011
organic hydroxy compound metabolic processGO:19016151470.011
regulation of chemotaxisGO:0050920740.011
cyclic nucleotide metabolic processGO:0009187820.011
endocytosisGO:00068971590.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
monocarboxylic acid biosynthetic processGO:0072330670.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
positive regulation of cell adhesionGO:0045785840.011
purine containing compound biosynthetic processGO:0072522880.011
negative regulation of immune responseGO:0050777400.011
negative regulation of hydrolase activityGO:00513461820.011
lung alveolus developmentGO:004828640.011
neuroblast proliferationGO:000740540.011
cell projection assemblyGO:00300311260.011
muscle system processGO:0003012810.011
tripartite regional subdivisionGO:000735120.011
anterior posterior axis specification embryoGO:000859520.011
response to metal ionGO:0010038840.011
stress activated mapk cascadeGO:0051403930.011
epithelium developmentGO:00604292270.011
regulation of cytoplasmic transportGO:19036491490.011
photoreceptor cell differentiationGO:004653020.011
regulation of meiosisGO:004002030.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
dna repairGO:00062811980.011
regulation of protein targetingGO:1903533910.011
nuclear importGO:00511701060.011
peptidyl serine modificationGO:00182091060.011
organelle assemblyGO:00709251760.011
protein acetylationGO:00064731160.011
regulation of innate immune responseGO:0045088970.011
negative regulation of cell cycleGO:00457861930.011
leukocyte chemotaxisGO:0030595760.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of peptidyl serine phosphorylation of stat proteinGO:003313930.011
proteasomal protein catabolic processGO:00104981760.011
inflammatory responseGO:0006954790.011
jak stat cascadeGO:0007259460.011
defense response to bacteriumGO:0042742630.011
sulfur compound metabolic processGO:00067901010.011
compound eye developmentGO:004874910.011
defense response to fungusGO:005083240.011
taxisGO:00423301570.011
regulation of transporter activityGO:0032409820.011
nucleotide biosynthetic processGO:00091651090.011
negative regulation of t helper 2 cell cytokine productionGO:200055220.011
response to light stimulusGO:0009416870.011
gtp metabolic processGO:00460392390.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of kinase activityGO:00336731060.011
circadian behaviorGO:004851220.011
zymogen activationGO:0031638700.011
protein import into nucleusGO:00066061040.011
negative regulation of cellular component movementGO:00512711060.011
negative regulation of multi organism processGO:0043901920.011
positive regulation of blood pressureGO:004577730.010
response to oxygen levelsGO:00704821000.010
negative regulation of organelle organizationGO:00106391260.010

INSL4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.037
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
musculoskeletal system diseaseDOID:172230.020
sensory system diseaseDOID:00501552030.018
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.016
inherited metabolic disorderDOID:6552420.016
neurodegenerative diseaseDOID:12891020.014
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
immune system diseaseDOID:29141550.013
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
retinal diseaseDOID:56791180.012
retinal degenerationDOID:8466890.012
myopathyDOID:4231040.012
disease of mental healthDOID:150700.011
acquired metabolic diseaseDOID:0060158580.011