Homo sapiens

94 known processes

HGS

hepatocyte growth factor-regulated tyrosine kinase substrate

(Aliases: FLJ11421,HRS,FLJ39878)

HGS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein deubiquitinationGO:0016579790.792
vesicle mediated transportGO:00161923710.790
protein catabolic processGO:00301633250.734
cytoplasmic transportGO:00164823790.718
endosomal transportGO:00161971290.683
Fly
cellular macromolecule catabolic processGO:00442653800.630
histone modificationGO:00165702510.591
protein modification by small protein conjugationGO:00324463420.588
Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.569
Fly
single organism cellular localizationGO:19025803320.531
covalent chromatin modificationGO:00165692540.510
protein ubiquitinationGO:00165673140.499
Fly
vacuolar transportGO:0007034340.468
positive regulation of catabolic processGO:00098963100.463
actin filament based processGO:00300292240.455
modulation of growth of symbiont involved in interaction with hostGO:004414420.426
chromatin modificationGO:00165682980.417
actin cytoskeleton organizationGO:00300362070.402
modification dependent protein catabolic processGO:00199412090.400
peptidyl lysine modificationGO:00182051440.378
mitotic cell cycle processGO:19030472860.375
golgi vesicle transportGO:0048193800.369
viral buddingGO:004675590.354
epithelial cell differentiationGO:00308551410.351
Fly
locomotory behaviorGO:000762610.350
spermatid developmentGO:000728640.331
g protein coupled receptor signaling pathwayGO:00071862070.328
regulation of exocytosisGO:0017157460.318
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.302
positive regulation of gtpase activityGO:00435471660.297
mitotic cell cycleGO:00002783260.279
glycosyl compound catabolic processGO:19016584130.255
spermatid differentiationGO:004851540.254
intracellular protein transportGO:00068862700.219
cell projection organizationGO:00300302520.217
positive regulation of phosphorylationGO:00423273940.212
guanosine containing compound metabolic processGO:19010682440.211
single organism membrane organizationGO:00448022680.194
positive regulation of proteolysisGO:00458621420.175
ras protein signal transductionGO:0007265730.172
regulation of proteolysisGO:00301622930.171
regulation of chromatin organizationGO:1902275560.169
cellular protein catabolic processGO:00442572610.167
establishment of protein localization to membraneGO:00901501210.165
regulation of vesicle mediated transportGO:00606271300.165
regulation of proteasomal protein catabolic processGO:0061136870.162
cell adhesionGO:00071553250.162
ubiquitin dependent protein catabolic processGO:00065112060.158
positive regulation of purine nucleotide catabolic processGO:00331231850.157
regulation of nucleoside metabolic processGO:00091182090.150
circulatory system developmentGO:00723592620.145
regulation of dna metabolic processGO:00510521530.144
regulation of secretion by cellGO:19035301770.141
small gtpase mediated signal transductionGO:0007264780.140
regulation of peptidase activityGO:00525471800.139
positive regulation of hydrolase activityGO:00513453310.136
maintenance of locationGO:00512351120.126
post embryonic developmentGO:000979120.126
Worm
defense responseGO:00069523150.125
nucleotide catabolic processGO:00091664080.124
innate immune responseGO:00450871780.123
regulation of cellular ketone metabolic processGO:0010565500.123
anatomical structure formation involved in morphogenesisGO:00486462840.122
protein polyubiquitinationGO:00002091100.119
dna packagingGO:0006323770.117
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.117
actin filament organizationGO:00070151280.116
nucleoside triphosphate catabolic processGO:00091433940.114
proteasomal protein catabolic processGO:00104981760.113
organelle fissionGO:00482851490.110
positive regulation of cellular component organizationGO:00511303760.107
negative regulation of intracellular signal transductionGO:19025321830.105
rab protein signal transductionGO:003248240.105
biological adhesionGO:00226103310.105
regulation of cell cycleGO:00517263930.101
Fly
endomembrane system organizationGO:00102561960.095
cell morphogenesisGO:00009022960.094
purine nucleoside catabolic processGO:00061523980.093
modification dependent macromolecule catabolic processGO:00436322120.093
regulation of growthGO:00400081650.092
establishment of protein localization to organelleGO:00725941720.091
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.091
proteolysis involved in cellular protein catabolic processGO:00516032440.089
regulation of endopeptidase activityGO:00525481700.087
cellular component morphogenesisGO:00329893140.086
ribonucleoside catabolic processGO:00424544060.085
regulation of anatomical structure morphogenesisGO:00226032860.082
inorganic ion transmembrane transportGO:00986602310.079
nucleoside catabolic processGO:00091644080.079
organelle assemblyGO:00709251760.078
nervous system developmentGO:00073992930.078
regulation of kinase activityGO:00435493140.077
regulation of cellular component movementGO:00512703340.076
Fly
cellular potassium ion transportGO:0071804600.074
cell projection morphogenesisGO:00488581290.073
plasma membrane organizationGO:00070091150.072
microtubule based processGO:00070172100.072
cellular response to endogenous stimulusGO:00714953360.072
Fly
positive regulation of protein catabolic processGO:0045732750.071
regulation of cell adhesionGO:00301551660.070
i kappab kinase nf kappab signalingGO:00072491660.070
endosome transport via multivesicular body sorting pathwayGO:003250930.070
Fly
regulation of protein catabolic processGO:00421761550.069
protein acetylationGO:00064731160.069
organ morphogenesisGO:00098871470.068
nitrogen compound transportGO:00717051910.068
growthGO:00400072020.068
regulation of cell projection organizationGO:00313441070.067
response to hormoneGO:00097251750.067
cellular response to oxygen containing compoundGO:19017012760.066
response to other organismGO:00517072610.065
regulation of small gtpase mediated signal transductionGO:00510561560.064
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.064
Fly
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.064
protein deacetylationGO:0006476380.063
purine nucleotide catabolic processGO:00061954050.063
embryo developmentGO:00097901230.062
Worm
mapk cascadeGO:00001652880.062
immune responseGO:00069553070.061
purine nucleoside triphosphate catabolic processGO:00091463920.061
response to oxygen containing compoundGO:19017003690.061
positive regulation of nucleotide metabolic processGO:00459812300.061
peptidyl lysine acetylationGO:00183941010.059
regulation of purine nucleotide catabolic processGO:00331212050.059
negative regulation of camp mediated signalingGO:004395140.058
protein targetingGO:00066051870.058
negative regulation of cellular protein metabolic processGO:00322693530.058
Fly
positive regulation of cellular catabolic processGO:00313312840.055
cell developmentGO:00484683280.054
Fly
dna repairGO:00062811980.054
protein oligomerizationGO:00512591730.053
ribonucleoside triphosphate metabolic processGO:00091994120.052
regulation of i kappab kinase nf kappab signalingGO:00431221620.051
regulation of gtp catabolic processGO:00331241800.051
secretion by cellGO:00329402260.050
membrane organizationGO:00610242920.050
protein deacylationGO:0035601390.050
purine ribonucleoside triphosphate catabolic processGO:00092073910.050
regulation of ras protein signal transductionGO:00465781550.050
meiosis iGO:000712740.050
potassium ion transportGO:0006813620.049
positive regulation of nucleotide catabolic processGO:00308131850.049
tube developmentGO:00352951250.049
hemopoiesisGO:00300971800.049
positive regulation of transferase activityGO:00513472270.048
regulation of transferase activityGO:00513383550.048
negative regulation of apoptotic processGO:00430663160.048
negative regulation of cellular component organizationGO:00511292350.047
nucleoside triphosphate metabolic processGO:00091414220.047
negative regulation of protein modification processGO:00314002000.047
Fly
positive regulation of protein kinase activityGO:00458601900.046
chromatin organizationGO:00063253510.046
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.046
purine ribonucleoside metabolic processGO:00461284370.046
negative regulation of potassium ion transmembrane transportGO:190138050.046
positive regulation of nucleoside metabolic processGO:00459791860.045
negative regulation of protein maturationGO:19033181420.044
regulation of protein localizationGO:00328802960.044
regulation of secretionGO:00510461940.044
intracellular receptor signaling pathwayGO:00305221040.043
negative regulation of cell deathGO:00605483450.042
cellular ketone metabolic processGO:0042180800.042
enzyme linked receptor protein signaling pathwayGO:00071673030.042
Fly
gene silencingGO:0016458490.042
signal transduction by phosphorylationGO:00230142970.041
regulation of apoptotic signaling pathwayGO:20012331750.041
protein localization to organelleGO:00333652800.041
multi organism membrane buddingGO:190259290.041
response to growth factorGO:00708482050.040
Fly
negative regulation of programmed cell deathGO:00430693210.040
protein autophosphorylationGO:00467771230.040
apoptotic mitochondrial changesGO:0008637570.040
female gamete generationGO:000729220.040
Fly
fibroblast growth factor receptor signaling pathwayGO:0008543260.039
Fly
ribonucleotide catabolic processGO:00092614050.039
regulation of chromosome organizationGO:00330441030.039
regulation of protein modification by small protein conjugation or removalGO:19033201070.039
Fly
cellular response to dna damage stimulusGO:00069743790.039
response to abiotic stimulusGO:00096283360.039
viral processGO:00160321460.039
adult locomotory behaviorGO:000834410.038
regulation of chromatin modificationGO:1903308510.038
multi organism membrane organizationGO:0044803120.038
epithelial cell developmentGO:0002064340.038
Fly
negative regulation of multi organism processGO:0043901920.037
dna conformation changeGO:00711031130.037
purine nucleoside triphosphate metabolic processGO:00091444120.037
regulation of cellular response to stressGO:00801352440.037
cell activationGO:00017752130.037
positive regulation of innate immune responseGO:0045089790.037
regulation of multi organism processGO:00439001570.036
purine ribonucleotide catabolic processGO:00091544040.036
protein acylationGO:00435431380.036
receptor metabolic processGO:0043112810.036
gtp catabolic processGO:00061842370.036
regulation of purine nucleotide metabolic processGO:19005422640.036
microtubule cytoskeleton organizationGO:00002261760.035
inorganic cation transmembrane transportGO:00986621940.035
regulation of cell differentiationGO:00455953930.035
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.034
positive regulation of secretionGO:00510471160.034
negative regulation of cytokine productionGO:0001818820.034
potassium ion transmembrane transportGO:0071805600.034
regulation of nucleotide catabolic processGO:00308112050.033
regulation of protein kinase activityGO:00458592890.033
guanosine containing compound catabolic processGO:19010692390.033
nucleoside phosphate catabolic processGO:19012924120.033
arf protein signal transductionGO:003201100.032
gtp metabolic processGO:00460392390.032
multicellular organismal agingGO:001025930.032
exosomal secretionGO:1990182150.032
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.032
defense response to bacteriumGO:0042742630.031
organophosphate catabolic processGO:00464344300.031
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.031
regulation of sequence specific dna binding transcription factor activityGO:00510902110.031
mrna metabolic processGO:00160711750.030
receptor mediated endocytosisGO:0006898840.030
positive regulation of protein phosphorylationGO:00019343130.030
apoptotic signaling pathwayGO:00971902680.029
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.029
secretionGO:00469032540.029
endocytosisGO:00068971590.029
Fly
segmentationGO:003528240.029
negative regulation of organelle organizationGO:00106391260.028
regulation of nucleotide metabolic processGO:00061402690.028
response to external biotic stimulusGO:00432072610.028
negative regulation of cell proliferationGO:00082852280.028
rna interferenceGO:001624640.028
mitotic nuclear divisionGO:00070671190.028
regulation of defense responseGO:00313471540.027
nucleoside monophosphate metabolic processGO:00091231910.027
cellular response to biotic stimulusGO:0071216710.027
memoryGO:000761330.027
receptor catabolic processGO:0032801110.027
muscle cell differentiationGO:0042692630.027
cell substrate junction assemblyGO:0007044350.027
negative regulation of protein transportGO:0051224750.027
positive regulation of transportGO:00510503360.027
spindle organizationGO:0007051530.027
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.026
negative regulation of catalytic activityGO:00430863350.026
regulation of establishment of protein localizationGO:00702012420.026
single organism reproductive processGO:0044702980.025
Fly
regulation of protein ubiquitinationGO:0031396950.025
Fly
protein k48 linked deubiquitinationGO:0071108190.025
ncrna metabolic processGO:00346601080.025
regulation of gtpase activityGO:00430871800.024
nuclear divisionGO:00002801280.024
viral life cycleGO:00190581320.024
neuron projection developmentGO:00311751060.024
cation transmembrane transportGO:00986552380.024
negative regulation of protein metabolic processGO:00512483910.023
Fly
response to nitrogen compoundGO:19016981840.023
cellular homeostasisGO:00197251960.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
regulation of cell motilityGO:20001452990.022
Fly
somitogenesisGO:000175620.022
multi organism cellular processGO:00447641560.022
regulation of cytokine productionGO:00018172320.022
t cell differentiation in thymusGO:003307740.022
response to decreased oxygen levelsGO:0036293960.022
positive regulation of organelle organizationGO:00106381950.021
neurogenesisGO:00220081690.021
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.021
cytokinesisGO:0000910960.021
endocytic recyclingGO:0032456120.020
regulation of response to external stimulusGO:00321012220.020
plasma membrane to endosome transportGO:004822760.020
lymphocyte activationGO:00466491330.020
multi organism organelle organizationGO:190259090.020
cell cell signalingGO:00072671550.020
post golgi vesicle mediated transportGO:0006892360.020
cell divisionGO:00513011680.020
regulation of exosomal secretionGO:1903541120.019
negative regulation of multicellular organismal processGO:00512413170.019
protein maturationGO:00516042330.019
determination of adult lifespanGO:000834020.019
regulation of ras gtpase activityGO:00323181280.019
brain morphogenesisGO:004885410.018
cell substrate adherens junction assemblyGO:0007045300.018
rna processingGO:00063962550.018
establishment of protein localization to plasma membraneGO:0090002680.018
negative regulation of ion transportGO:0043271390.018
purine ribonucleoside catabolic processGO:00461303980.018
rna export from nucleusGO:0006405330.018
leukocyte activationGO:00453211640.018
regulation of dna repairGO:0006282470.018
protein localization to plasma membraneGO:0072659930.018
lysosomal transportGO:0007041330.018
negative regulation of kinase activityGO:00336731060.017
positive regulation of cell differentiationGO:00455972110.017
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.017
Fly
positive regulation of protein localization to early endosomeGO:190296620.017
regulation of epithelial cell migrationGO:0010632930.017
Fly
cellular response to lipidGO:00713961270.017
protein k63 linked deubiquitinationGO:0070536210.017
cell cycle checkpointGO:00000751170.017
regulation of immune responseGO:00507762010.017
positive regulation of intracellular transportGO:00323881040.017
regulation of histone modificationGO:0031056470.017
visual learningGO:000854210.017
negative regulation of phosphorylationGO:00423261740.016
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.016
monovalent inorganic cation transportGO:00156721280.016
spermatogenesisGO:0007283220.016
immune system developmentGO:00025201950.016
regulation of protein deubiquitinationGO:009008540.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
interspecies interaction between organismsGO:00444191560.016
virion assemblyGO:0019068140.016
regulation of response to dna damage stimulusGO:2001020940.016
positive regulation of protein ubiquitinationGO:0031398530.016
Fly
regulation of gene expression epigeneticGO:0040029730.016
protein targeting to vacuoleGO:000662380.016
negative regulation of locomotionGO:00400131180.016
adherens junction organizationGO:0034332360.016
amine metabolic processGO:0009308440.015
positive regulation of defense responseGO:0031349870.015
negative regulation of protein processingGO:00109551420.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
regulation of cytoskeleton organizationGO:00514931770.015
cell matrix adhesionGO:0007160850.015
positive regulation of rab gtpase activityGO:0032851390.015
cellular response to hormone stimulusGO:00328701250.015
regulation of mapk cascadeGO:00434082620.015
regulation of neuron projection developmentGO:0010975570.015
cellular amino acid metabolic processGO:00065201160.015
metal ion homeostasisGO:00550651690.014
epidermis morphogenesisGO:004873030.014
protein homooligomerizationGO:00512601000.014
rrna metabolic processGO:0016072400.014
response to cytokineGO:00340972320.014
regulation of bindingGO:00510981110.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
regulation of cellular component biogenesisGO:00440872810.014
protein processingGO:00164852260.014
multi organism reproductive processGO:0044703540.014
Fly
immune response activating signal transductionGO:0002757900.014
protein k48 linked ubiquitinationGO:0070936380.014
chromosome segregationGO:00070591140.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
protein localization to membraneGO:00726571600.013
positive regulation of secretion by cellGO:19035321080.013
positive regulation of peptidase activityGO:0010952880.013
regulation of ubiquitin protein transferase activityGO:0051438280.013
ncrna processingGO:0034470830.013
steroid metabolic processGO:0008202940.013
cation transportGO:00068123310.013
cell junction assemblyGO:0034329670.013
regulation of response to cytokine stimulusGO:0060759460.013
actin cytoskeleton reorganizationGO:0031532370.013
negative regulation of transportGO:00510511760.013
negative regulation of phosphorus metabolic processGO:00105632670.013
Fly
hematopoietic or lymphoid organ developmentGO:00485341860.013
neuron projection morphogenesisGO:0048812500.013
lipid localizationGO:00108761060.013
negative regulation of growthGO:0045926970.013
cytokine productionGO:00018162470.013
generation of neuronsGO:00486991520.013
purine containing compound catabolic processGO:00725234110.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
golgi to plasma membrane protein transportGO:0043001190.013
lipid storageGO:0019915280.012
actomyosin structure organizationGO:0031032590.012
skin developmentGO:0043588760.012
muscle structure developmentGO:0061061980.012
response to organic cyclic compoundGO:00140702040.012
early endosome to late endosome transportGO:0045022210.012
regulation of cellular protein catabolic processGO:1903362960.012
regulation of cell morphogenesisGO:00226041530.012
toll signaling pathwayGO:000806320.012
Fly
regulation of pinocytosisGO:004854860.012
negative regulation of voltage gated calcium channel activityGO:190138640.012
behaviorGO:00076101120.012
multivesicular body assemblyGO:003625810.012
second messenger mediated signalingGO:0019932780.012
developmental process involved in reproductionGO:0003006660.011
Fly
regulation of intracellular transportGO:00323861950.011
cardiovascular system developmentGO:00723582620.011
mitotic cell cycle phase transitionGO:00447721620.011
cellular component assembly involved in morphogenesisGO:0010927730.011
single organismal cell cell adhesionGO:00163371480.011
regulation of leukocyte activationGO:00026941150.011
multicellular organismal reproductive processGO:0048609400.011
Fly
camp mediated signalingGO:0019933230.011
male gamete generationGO:0048232220.011
negative regulation of apoptotic signaling pathwayGO:2001234970.011
cell part morphogenesisGO:00329901370.011
negative regulation of mitotic cell cycleGO:00459301020.011
regulation of cell growthGO:00015581350.011
cellular chemical homeostasisGO:00550821800.011
canonical wnt signaling pathwayGO:00600701160.011
transmembrane transportGO:00550853990.011
cellular response to organic cyclic compoundGO:00714071270.011
reproductionGO:0000003630.011
Worm Fly
cellular response to molecule of bacterial originGO:0071219620.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
interleukin 8 productionGO:0032637510.010
regulation of interleukin 2 secretionGO:190004020.010
negative regulation of epithelial cell migrationGO:0010633380.010
histone acetylationGO:0016573930.010
regulation of protein targetingGO:1903533910.010

HGS disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:18400.427
kidney diseaseDOID:557360.419
disease of mental healthDOID:150700.074
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
disease of cellular proliferationDOID:145661740.022
organ system cancerDOID:00506861640.017
cancerDOID:1621670.017
glomerulosclerosisDOID:005085160.016
nephritisDOID:1095260.016
glomerulonephritisDOID:292160.016
focal segmental glomerulosclerosisDOID:131260.016