Homo sapiens

0 known processes

IRF3

interferon regulatory factor 3

IRF3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of interferon beta biosynthetic processGO:004535740.779
Mouse
serine phosphorylation of stat proteinGO:004250140.527
regulation of interferon alpha productionGO:0032647110.470
Human Mouse
positive regulation of interferon beta productionGO:0032728170.378
Human Mouse
nervous system developmentGO:00073992930.355
interferon beta productionGO:0032608230.286
Human Mouse
cellular amine metabolic processGO:0044106410.260
regulation of cellular ketone metabolic processGO:0010565500.256
positive regulation of interferon alpha productionGO:0032727110.254
Human Mouse
positive regulation of apoptotic processGO:00430652460.247
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.244
Mouse
cellular response to dna damage stimulusGO:00069743790.224
blood vessel developmentGO:00015681720.210
positive regulation of immune system processGO:00026842830.209
Mouse
regulation of mapk cascadeGO:00434082620.200
negative regulation of cell proliferationGO:00082852280.200
regulation of cytokine productionGO:00018172320.184
Human Mouse
single organism cellular localizationGO:19025803320.183
negative regulation of phosphate metabolic processGO:00459362670.180
regulation of cellular amine metabolic processGO:0033238110.179
regulation of i kappab kinase nf kappab signalingGO:00431221620.164
chemical homeostasisGO:00488783060.161
regulation of interferon beta productionGO:0032648220.154
Human Mouse
response to external biotic stimulusGO:00432072610.154
Human Mouse
negative regulation of protein modification processGO:00314002000.151
enzyme linked receptor protein signaling pathwayGO:00071673030.146
mapk cascadeGO:00001652880.146
apoptotic signaling pathwayGO:00971902680.145
locomotory behaviorGO:000762610.138
regulation of type i interferon productionGO:0032479260.137
Human Mouse
negative regulation of phosphorylationGO:00423261740.133
negative regulation of protein metabolic processGO:00512483910.130
Mouse
response to cytokineGO:00340972320.130
Human Mouse
type i interferon productionGO:0032606270.124
Human Mouse
response to other organismGO:00517072610.123
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.123
defense response to bacteriumGO:0042742630.114
hematopoietic or lymphoid organ developmentGO:00485341860.113
response to abiotic stimulusGO:00096283360.112
Human
cellular response to cytokine stimulusGO:00713451810.111
Human Mouse
positive regulation of nf kappab transcription factor activityGO:0051092810.109
defense responseGO:00069523150.102
Human Mouse
positive regulation of programmed cell deathGO:00430682490.102
somatic muscle developmentGO:000752510.101
membrane organizationGO:00610242920.100
negative regulation of catalytic activityGO:00430863350.098
rhythmic behaviorGO:000762220.095
negative regulation of intracellular signal transductionGO:19025321830.094
signal transduction by phosphorylationGO:00230142970.094
tube developmentGO:00352951250.091
vasculature developmentGO:00019441810.090
jak stat cascadeGO:0007259460.090
transmembrane transportGO:00550853990.089
protein modification by small protein conjugationGO:00324463420.085
protein targetingGO:00066051870.083
peptidyl serine phosphorylationGO:00181051010.083
type i interferon signaling pathwayGO:0060337110.082
Mouse
positive regulation of defense responseGO:0031349870.082
Mouse
intracellular protein transportGO:00068862700.081
protein localization to membraneGO:00726571600.080
regulation of protein serine threonine kinase activityGO:00719001790.078
positive regulation of cytokine productionGO:00018191670.074
Human Mouse
single organism membrane organizationGO:00448022680.074
cellular cation homeostasisGO:00300031630.074
cellular response to oxidative stressGO:0034599850.073
positive regulation of cell differentiationGO:00455972110.073
establishment of protein localization to organelleGO:00725941720.072
cellular response to external stimulusGO:00714961110.072
Human
i kappab kinase nf kappab signalingGO:00072491660.072
response to nitrogen compoundGO:19016981840.071
Mouse
regulation of homeostatic processGO:00328441210.070
brain developmentGO:0007420970.070
response to biotic stimulusGO:00096072760.070
Human Mouse
positive regulation of interferon beta biosynthetic processGO:004535940.069
cytokine mediated signaling pathwayGO:00192211090.068
Mouse
peptidyl lysine acetylationGO:00183941010.068
response to bacteriumGO:00096171440.067
Mouse
amine metabolic processGO:0009308440.067
cardiovascular system developmentGO:00723582620.066
peptidyl tyrosine phosphorylationGO:00181081700.066
hemopoiesisGO:00300971800.065
microtubule based processGO:00070172100.065
positive regulation of developmental processGO:00510943140.065
negative regulation of phosphorus metabolic processGO:00105632670.065
immune system developmentGO:00025201950.064
cell activationGO:00017752130.063
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.063
negative regulation of protein phosphorylationGO:00019331400.062
positive regulation of immune responseGO:00507781590.062
Mouse
regulation of cell differentiationGO:00455953930.062
establishment of protein localization to membraneGO:00901501210.061
alcohol metabolic processGO:00060661140.061
immune responseGO:00069553070.061
Human Mouse
circadian behaviorGO:004851220.061
embryo developmentGO:00097901230.060
positive regulation of innate immune responseGO:0045089790.060
Mouse
rna splicingGO:00083801310.060
regulation of immune responseGO:00507762010.059
Human Mouse
glycerolipid metabolic processGO:00464861070.059
positive regulation of cell deathGO:00109422630.059
regulation of cellular amino acid metabolic processGO:000652160.058
protein acetylationGO:00064731160.058
peptidyl serine modificationGO:00182091060.057
defense response to virusGO:0051607710.056
Human Mouse
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.055
organonitrogen compound biosynthetic processGO:19015662000.054
negative regulation of homeostatic processGO:0032845590.053
internal peptidyl lysine acetylationGO:0018393970.053
negative regulation of developmental processGO:00510932470.053
regulation of sequence specific dna binding transcription factor activityGO:00510902110.053
negative regulation of cell differentiationGO:00455961710.053
positive regulation of type i interferon mediated signaling pathwayGO:006034040.051
Mouse
cellular amino acid metabolic processGO:00065201160.051
myeloid cell homeostasisGO:0002262340.050
cellular biogenic amine metabolic processGO:0006576340.050
endocytic recyclingGO:0032456120.050
positive regulation of type i interferon productionGO:0032481200.050
Human Mouse
nitrogen cycle metabolic processGO:007194130.050
mrna metabolic processGO:00160711750.049
cation homeostasisGO:00550801890.049
oogenesisGO:004847720.049
cellular homeostasisGO:00197251960.048
response to oxidative stressGO:00069791210.048
response to oxygen containing compoundGO:19017003690.048
Mouse
cellular ketone metabolic processGO:0042180800.047
response to virusGO:00096151260.047
Human Mouse
organophosphate biosynthetic processGO:00904071630.046
endomembrane system organizationGO:00102561960.045
internal protein amino acid acetylationGO:00064751010.045
response to mechanical stimulusGO:0009612510.045
Human
regulation of peptidase activityGO:00525471800.045
neurogenesisGO:00220081690.044
post embryonic developmentGO:000979120.044
leukocyte differentiationGO:0002521980.044
negative regulation of cellular protein metabolic processGO:00322693530.043
oocyte developmentGO:004859910.043
regulation of apoptotic signaling pathwayGO:20012331750.043
cell agingGO:0007569520.042
defense response to other organismGO:00985421290.041
Human Mouse
female gamete generationGO:000729220.041
positive regulation of peptidase activityGO:0010952880.040
microtubule cytoskeleton organizationGO:00002261760.039
segmentationGO:003528240.039
head developmentGO:00603221080.038
positive regulation of hydrolase activityGO:00513453310.038
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.038
central nervous system developmentGO:00074171230.037
positive regulation of cellular component organizationGO:00511303760.037
cytoplasmic transportGO:00164823790.037
compound eye developmentGO:004874910.036
cell divisionGO:00513011680.036
negative regulation of cell deathGO:00605483450.036
histone modificationGO:00165702510.035
cell cycle arrestGO:0007050710.035
Human
covalent chromatin modificationGO:00165692540.035
regulation of endopeptidase activityGO:00525481700.034
lipid metabolic processGO:00066293810.034
post embryonic organ developmentGO:004856910.034
mrna processingGO:00063971330.034
histone acetylationGO:0016573930.034
extrinsic apoptotic signaling pathwayGO:00971911190.033
negative regulation of canonical wnt signaling pathwayGO:0090090550.033
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.033
blastoderm segmentationGO:000735020.032
epithelium developmentGO:00604292270.032
nucleoside phosphate biosynthetic processGO:19012931090.032
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.032
determination of adult lifespanGO:000834020.032
neuron developmentGO:00486661130.031
rna processingGO:00063962550.031
positive regulation of phosphorylationGO:00423273940.031
regulation of keratinocyte apoptotic processGO:190217210.031
single organism carbohydrate metabolic processGO:00447231930.031
erythrocyte homeostasisGO:0034101310.031
positive regulation of chromatin modificationGO:1903310300.031
oxidation reduction processGO:00551143960.030
positive regulation of triglyceride biosynthetic processGO:001086740.030
innate immune responseGO:00450871780.030
Mouse
metal ion transportGO:00300012720.030
response to inorganic substanceGO:00100351270.030
regulation of protein kinase activityGO:00458592890.029
intrinsic apoptotic signaling pathwayGO:00971931270.029
plasma membrane organizationGO:00070091150.028
cellular response to type i interferonGO:0071357120.028
Mouse
myeloid cell differentiationGO:00300991170.028
mitotic cell cycle processGO:19030472860.028
angiogenesisGO:00015251470.028
negative regulation of apoptotic processGO:00430663160.028
regulation of autophagyGO:0010506520.028
positive regulation of cellular amine metabolic processGO:003324070.028
cellular response to mechanical stimulusGO:0071260390.028
Human
positive regulation of dna metabolic processGO:0051054730.027
mitochondrial membrane organizationGO:0007006400.027
monovalent inorganic cation homeostasisGO:0055067370.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
negative regulation of programmed cell deathGO:00430693210.027
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.026
memoryGO:000761330.026
anion transportGO:00068201610.026
negative regulation of cell cycleGO:00457861930.026
Human
cell developmentGO:00484683280.026
mrna 3 end processingGO:0031124240.026
g protein coupled receptor signaling pathwayGO:00071862070.026
peptide transportGO:0015833740.026
protein localization to organelleGO:00333652800.025
axon cargo transportGO:000808820.025
regulation of jak stat cascadeGO:0046425440.025
regulation of establishment of protein localizationGO:00702012420.025
regulation of cysteine type endopeptidase activityGO:20001161270.025
response to nitric oxideGO:007173140.025
positive regulation of cellular catabolic processGO:00313312840.025
cell type specific apoptotic processGO:00972851250.025
cellular response to nitrogen compoundGO:19016991440.024
cellular ion homeostasisGO:00068731680.024
regulation of type i interferon mediated signaling pathwayGO:006033890.024
Mouse
multicellular organismal agingGO:001025930.024
keratinocyte apoptotic processGO:009728310.024
vesicle mediated transportGO:00161923710.024
oocyte differentiationGO:000999420.024
cell morphogenesisGO:00009022960.024
anatomical structure formation involved in morphogenesisGO:00486462840.023
response to organonitrogen compoundGO:00102431560.023
response to glucagonGO:003376210.023
regulation of response to dna damage stimulusGO:2001020940.023
dna biosynthetic processGO:0071897400.023
positive regulation of autophagyGO:0010508240.023
negative regulation of cellular amino acid metabolic processGO:004576320.022
microtubule bundle formationGO:0001578150.022
immune response regulating signaling pathwayGO:0002764970.022
interferon alpha productionGO:0032607110.022
Human Mouse
ion transmembrane transportGO:00342203380.022
cellular response to endogenous stimulusGO:00714953360.022
negative regulation of kinase activityGO:00336731060.022
positive regulation of endopeptidase activityGO:0010950840.022
regulation of protein localizationGO:00328802960.022
regulation of cell cycleGO:00517263930.022
Human
response to radiationGO:00093141510.021
neuron deathGO:0070997650.021
hormone transportGO:0009914680.021
response to toxic substanceGO:0009636370.021
sensory organ developmentGO:0007423520.021
epithelial cell differentiationGO:00308551410.020
regulation of innate immune responseGO:0045088970.020
Mouse
negative regulation of mapk cascadeGO:0043409560.020
regulation of mitotic cell cycleGO:00073461890.020
glycerolipid biosynthetic processGO:0045017510.020
positive regulation of cytokine mediated signaling pathwayGO:0001961120.020
Mouse
phospholipid metabolic processGO:0006644990.020
regulation of secretionGO:00510461940.020
spermatid differentiationGO:004851540.020
purine nucleotide biosynthetic processGO:0006164840.020
osteoblast differentiationGO:0001649920.020
organic hydroxy compound metabolic processGO:19016151470.019
regulation of cytokine mediated signaling pathwayGO:0001959410.019
Mouse
muscle structure developmentGO:0061061980.019
regulation of myeloid cell differentiationGO:0045637810.019
positive regulation of transportGO:00510503360.019
cation transportGO:00068123310.019
establishment of protein localization to plasma membraneGO:0090002680.019
protein localization to plasma membraneGO:0072659930.019
leukocyte activationGO:00453211640.019
regulation of kinase activityGO:00435493140.019
protein deubiquitinationGO:0016579790.019
chloride transmembrane transportGO:1902476380.019
neurological system processGO:00508771630.019
regulation of lipid biosynthetic processGO:0046890470.019
hindbrain developmentGO:003090230.019
hexose metabolic processGO:0019318550.019
embryonic morphogenesisGO:0048598850.019
immune response activating cell surface receptor signaling pathwayGO:0002429450.019
nuclear importGO:00511701060.019
innate immune response activating signal transductionGO:0002758480.019
generation of neuronsGO:00486991520.018
glycerophospholipid metabolic processGO:0006650840.018
lymphocyte homeostasisGO:000226040.018
adaptive immune responseGO:0002250490.018
Human
positive regulation of homeostatic processGO:0032846470.018
cell projection organizationGO:00300302520.018
negative regulation of wnt signaling pathwayGO:0030178690.018
regulation of neural precursor cell proliferationGO:200017740.018
cellular carbohydrate metabolic processGO:0044262840.018
response to uvGO:0009411730.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
neuron differentiationGO:00301821380.017
regulation of cell growthGO:00015581350.017
protein ubiquitinationGO:00165673140.017
mitochondrial transportGO:0006839600.017
regulation of angiogenesisGO:0045765920.017
renal system developmentGO:0072001630.017
histone serine phosphorylationGO:003540440.017
positive regulation of histone deacetylase activityGO:190172730.016
negative regulation of transferase activityGO:00513481240.016
response to light stimulusGO:0009416870.016
regulation of lymphocyte activationGO:00512491030.016
positive regulation of cytokine biosynthetic processGO:0042108250.016
positive regulation of myeloid cell differentiationGO:0045639390.016
secretion by cellGO:00329402260.016
neuroblast proliferationGO:000740540.016
lymphocyte activationGO:00466491330.016
negative regulation of g0 to g1 transitionGO:007031720.016
mitotic cell cycleGO:00002783260.016
regulation of hormone levelsGO:00108171250.016
activation of immune responseGO:00022531140.016
spermatid developmentGO:000728640.016
negative regulation of protein kinase activityGO:0006469980.016
system processGO:00030083490.016
actin filament bundle organizationGO:0061572540.016
stem cell developmentGO:0048864690.016
regulation of erythrocyte differentiationGO:0045646170.016
positive regulation of lipid biosynthetic processGO:0046889220.016
lymphocyte mediated immunityGO:0002449480.015
immune response activating signal transductionGO:0002757900.015
response to hormoneGO:00097251750.015
erythrocyte differentiationGO:0030218280.015
monovalent inorganic cation transportGO:00156721280.015
peptide hormone secretionGO:0030072500.015
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoterGO:007236610.015
epidermis developmentGO:0008544590.015
visual learningGO:000854210.015
rna polyadenylationGO:0043631140.015
protein processingGO:00164852260.015
regulation of plasma lipoprotein particle levelsGO:0097006320.015
regenerationGO:003109940.015
protein importGO:00170381300.015
response to peptide hormoneGO:0043434610.015
embryonic placenta developmentGO:000189210.015
regulation of proteolysisGO:00301622930.015
cellular response to insulin stimulusGO:0032869410.015
protein autophosphorylationGO:00467771230.014
skin developmentGO:0043588760.014
gland developmentGO:0048732480.014
positive regulation of erythrocyte differentiationGO:0045648110.014
carbohydrate derivative biosynthetic processGO:19011372070.014
cellular response to growth factor stimulusGO:00713631970.014
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043630.014
positive regulation of interleukin 4 biosynthetic processGO:004540410.014
cellular lipid metabolic processGO:00442553030.014
morphogenesis of embryonic epitheliumGO:001633140.014
nuclear transportGO:00511691790.014
regulation of cell activationGO:00508651250.014
blood vessel morphogenesisGO:00485141620.014
regulation of growthGO:00400081650.014
response to tumor necrosis factorGO:0034612760.014
response to drugGO:0042493810.013
chromatin modificationGO:00165682980.013
positive regulation of keratinocyte apoptotic processGO:190217410.013
stem cell differentiationGO:0048863930.013
neuron remodelingGO:001632220.013
defense response to gram negative bacteriumGO:0050829140.013
dephosphorylationGO:00163112090.013
positive regulation of secretionGO:00510471160.013
amino acid importGO:004309040.013
positive regulation of mitochondrial membrane permeabilityGO:0035794170.013
apoptotic process involved in morphogenesisGO:006056130.013
regulation of transporter activityGO:0032409820.013
carbohydrate metabolic processGO:00059752070.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.013
cellular component morphogenesisGO:00329893140.013
regulation of dna metabolic processGO:00510521530.013
positive regulation of ion transmembrane transportGO:0034767400.013
cell death in response to oxidative stressGO:0036473290.013
endoplasmic reticulum organizationGO:0007029200.013
regulation of neuron apoptotic processGO:0043523350.013
regulation of protein catabolic processGO:00421761550.013
visual behaviorGO:000763220.012
response to growth factorGO:00708482050.012
cellular response to oxygen containing compoundGO:19017012760.012
Mouse
positive regulation of mapk cascadeGO:00434101900.012
regulation of adaptive immune responseGO:0002819330.012
Human
response to type i interferonGO:0034340140.012
Mouse
regulation of map kinase activityGO:00434051080.012
positive regulation of cell proliferationGO:00082843010.012
regulation of intracellular transportGO:00323861950.012
urea metabolic processGO:001962730.012
mitotic cell cycle checkpointGO:0007093680.012
regulation of cholesterol homeostasisGO:200018820.012
maintenance of locationGO:00512351120.012
generation of precursor metabolites and energyGO:0006091680.012
regulation of secretion by cellGO:19035301770.012
peptidyl lysine modificationGO:00182051440.012
positive regulation of protein complex assemblyGO:0031334860.012
digestive tract developmentGO:0048565750.012
cellular response to peptide hormone stimulusGO:0071375560.012
peptidyl tyrosine modificationGO:00182121700.012
mammary gland morphogenesisGO:006044320.012
regulation of membrane permeabilityGO:0090559250.012
histone h4 acetylationGO:0043967470.011
striated muscle cell differentiationGO:0051146430.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.011
cytokine productionGO:00018162470.011
Human Mouse
cellular macromolecular complex assemblyGO:00346223240.011
response to decreased oxygen levelsGO:0036293960.011
endosomal transportGO:00161971290.011
regulation of lipid metabolic processGO:0019216960.011
organic hydroxy compound transportGO:0015850630.011
regulation of cellular response to stressGO:00801352440.011
cellular response to reactive nitrogen speciesGO:190217020.011
b cell homeostasisGO:000178210.011
tripartite regional subdivisionGO:000735120.011
homeostasis of number of cellsGO:0048872400.011
golgi vesicle transportGO:0048193800.011
regulation of peptidyl serine phosphorylationGO:0033135500.011
sensory perceptionGO:00076001030.011
anatomical structure homeostasisGO:00602491000.011
regulation of cell cycle phase transitionGO:19019871260.011
mitochondrion organizationGO:00070051560.011
positive regulation of bindingGO:0051099450.011
inorganic anion transportGO:0015698600.011
phosphatidylcholine metabolic processGO:0046470190.011
cellular response to radiationGO:0071478650.011
regulation of transferase activityGO:00513383550.011
pyridine containing compound biosynthetic processGO:007252530.011
regulation of neuron deathGO:1901214560.011
cellular response to extracellular stimulusGO:0031668720.011
positive regulation of interleukin 2 productionGO:0032743110.011
camp biosynthetic processGO:0006171470.011
response to cocaineGO:004222010.011
regulation of anatomical structure sizeGO:00900661010.011
protein maturationGO:00516042330.010
negative regulation of developmental growthGO:0048640100.010
regulation of receptor activityGO:0010469470.010
response to hyperoxiaGO:005509340.010
cytokine metabolic processGO:0042107380.010
Mouse
neuron projection developmentGO:00311751060.010
positive regulation of neuron deathGO:1901216140.010
interleukin 8 productionGO:0032637510.010
negative regulation of hydrolase activityGO:00513461820.010
chromosome segregationGO:00070591140.010
regulation of protein complex assemblyGO:00432541470.010
regulation of wnt signaling pathwayGO:00301111230.010

IRF3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.115
Human
cancerDOID:1621670.112
Human
organ system cancerDOID:00506861640.105
Human
central nervous system diseaseDOID:3311860.084
nervous system diseaseDOID:8634310.084
disease of metabolismDOID:00146672950.043
neurodegenerative diseaseDOID:12891020.040
synucleinopathyDOID:0050890220.040
musculoskeletal system diseaseDOID:172230.014
connective tissue diseaseDOID:651090.014
gastrointestinal system cancerDOID:3119520.013
Human
brain diseaseDOID:936730.013
epilepsy syndromeDOID:1826410.013
large intestine cancerDOID:5672290.011
intestinal cancerDOID:10155290.011
colorectal cancerDOID:9256290.011