Homo sapiens

0 known processes

IRF9

interferon regulatory factor 9

(Aliases: p48,IRF-9,ISGF3G,ISGF3)

IRF9 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to interferon betaGO:0035456110.987
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.947
response to other organismGO:00517072610.933
Human
innate immune responseGO:00450871780.928
viral life cycleGO:00190581320.920
negative regulation of viral processGO:0048525660.912
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.905
immune responseGO:00069553070.867
Human
response to biotic stimulusGO:00096072760.854
Human
defense responseGO:00069523150.851
Human
positive regulation of interleukin 4 biosynthetic processGO:004540410.842
response to interferon alphaGO:0035455110.825
viral genome replicationGO:0019079500.817
cellular response to cytokine stimulusGO:00713451810.764
Human
interleukin 4 mediated signaling pathwayGO:003577130.727
regulation of viral processGO:00507921030.726
interspecies interaction between organismsGO:00444191560.696
cytokine mediated signaling pathwayGO:00192211090.689
intracellular protein transportGO:00068862700.685
regulation of viral genome replicationGO:0045069480.663
response to cytokineGO:00340972320.623
Human
positive regulation of interleukin 13 productionGO:003273640.604
positive regulation of cytokine productionGO:00018191670.601
Human
defense response to other organismGO:00985421290.590
Human
interleukin 4 biosynthetic processGO:004209720.587
negative regulation of multi organism processGO:0043901920.586
response to external biotic stimulusGO:00432072610.582
Human
negative regulation of cell proliferationGO:00082852280.548
type i interferon signaling pathwayGO:0060337110.534
positive regulation of type i interferon productionGO:0032481200.531
Human
response to interferon gammaGO:0034341390.510
nucleocytoplasmic transportGO:00069131760.510
regulation of regulatory t cell differentiationGO:004558940.491
nuclear transportGO:00511691790.464
response to type i interferonGO:0034340140.460
cytoplasmic transportGO:00164823790.457
multi organism cellular processGO:00447641560.455
negative regulation of multicellular organismal processGO:00512413170.455
cellular response to interferon gammaGO:0071346240.442
response to virusGO:00096151260.421
Human
immune effector processGO:00022521590.410
Human
jak stat cascade involved in growth hormone signaling pathwayGO:006039720.407
defense response to virusGO:0051607710.381
Human
negative regulation of gene silencing by rnaGO:006096730.352
viral transcriptionGO:0019083350.326
interleukin 6 mediated signaling pathwayGO:007010270.305
negative regulation of cellular protein metabolic processGO:00322693530.303
single organism nuclear importGO:19025931040.285
regulation of vasculature developmentGO:1901342970.284
regulation of defense responseGO:00313471540.284
positive regulation of cell deathGO:00109422630.282
Human
cellular response to type i interferonGO:0071357120.269
response to lipidGO:00339932060.260
regulation of adaptive immune responseGO:0002819330.258
Human
nucleoside phosphate biosynthetic processGO:19012931090.240
negative regulation of viral genome replicationGO:0045071350.240
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.236
immune response regulating signaling pathwayGO:0002764970.229
glycosylationGO:0070085710.223
regulation of intracellular transportGO:00323861950.219
viral gene expressionGO:0019080350.215
viral processGO:00160321460.211
negative regulation of vasculature developmentGO:1901343430.202
positive regulation of interferon alpha productionGO:0032727110.199
Human
protein localization to organelleGO:00333652800.198
interferon gamma mediated signaling pathwayGO:006033370.195
negative regulation of catalytic activityGO:00430863350.190
anatomical structure formation involved in morphogenesisGO:00486462840.187
negative regulation of developmental processGO:00510932470.183
base conversion or substitution editingGO:001655340.183
regulation of innate immune responseGO:0045088970.182
regulation of anatomical structure morphogenesisGO:00226032860.178
positive regulation of viral entry into host cellGO:004659830.171
protein glycosylationGO:0006486620.162
entry into hostGO:0044409250.159
positive regulation of rig i signaling pathwayGO:190024640.155
negative regulation of angiogenesisGO:0016525390.147
negative regulation of protein metabolic processGO:00512483910.143
epithelial cell proliferationGO:00506731280.143
detection of chemical stimulus involved in sensory perceptionGO:0050907330.141
single organism cellular localizationGO:19025803320.140
establishment of protein localization to organelleGO:00725941720.140
cytokine productionGO:00018162470.136
Human Mouse
posttranscriptional regulation of gene expressionGO:00106082130.129
negative regulation of epithelial cell proliferationGO:0050680480.127
endothelial cell proliferationGO:0001935650.119
renal tubule developmentGO:0061326190.119
regulation of i kappab kinase nf kappab signalingGO:00431221620.116
growth hormone receptor signaling pathwayGO:0060396100.113
negative regulation of defense responseGO:0031348470.108
interaction with hostGO:0051701420.107
intracellular receptor signaling pathwayGO:00305221040.104
negative regulation of calcium ion importGO:009028110.102
cellular response to nitrogen compoundGO:19016991440.100
interleukin 2 productionGO:0032623200.100
regulation of cellular component movementGO:00512703340.099
renal system developmentGO:0072001630.099
macromolecule glycosylationGO:0043413630.097
negative regulation of immune responseGO:0050777400.096
cardiovascular system developmentGO:00723582620.096
positive regulation of programmed cell deathGO:00430682490.094
Human
negative regulation of phosphate metabolic processGO:00459362670.092
negative regulation of cell differentiationGO:00455961710.091
negative regulation of locomotionGO:00400131180.091
protein importGO:00170381300.091
regulation of defense response to virusGO:0050688330.087
regulation of interleukin 12 productionGO:0032655150.085
protein import into nucleusGO:00066061040.085
osteoblast differentiationGO:0001649920.085
regulation of locomotionGO:00400123290.084
regulation of angiogenesisGO:0045765920.083
positive regulation of innate immune responseGO:0045089790.083
positive regulation of developmental processGO:00510943140.082
pattern recognition receptor signaling pathwayGO:0002221480.082
regulation of apoptotic signaling pathwayGO:20012331750.078
negative regulation of immune system processGO:00026831360.076
cellular response to oxygen containing compoundGO:19017012760.075
negative regulation of intracellular signal transductionGO:19025321830.074
positive regulation of interferon beta productionGO:0032728170.072
Human
interleukin 13 productionGO:003261670.072
protein targeting to nucleusGO:00447441040.072
regulation of multi organism processGO:00439001570.070
modification dependent macromolecule catabolic processGO:00436322120.070
protein processingGO:00164852260.070
negative regulation of protein processingGO:00109551420.069
protein targetingGO:00066051870.069
response to nitrogen compoundGO:19016981840.068
Human
regulation of interferon alpha productionGO:0032647110.067
Human
carbohydrate derivative biosynthetic processGO:19011372070.066
negative regulation of blood vessel morphogenesisGO:2000181410.065
modification dependent protein catabolic processGO:00199412090.063
regulation of protein maturationGO:19033171500.061
protein maturationGO:00516042330.061
activation of immune responseGO:00022531140.061
macrophage fusionGO:003423810.061
blood vessel developmentGO:00015681720.060
regulation of cell migrationGO:00303342890.060
protein oligomerizationGO:00512591730.059
regulation of cell cycleGO:00517263930.057
Human
negative regulation of endothelial cell proliferationGO:0001937200.055
regulation of interleukin 2 productionGO:0032663190.054
nucleotide biosynthetic processGO:00091651090.054
response to organic cyclic compoundGO:00140702040.054
regulation of cytokine productionGO:00018172320.054
Human
protein ubiquitinationGO:00165673140.053
regulation of interleukin 4 biosynthetic processGO:004540220.053
regulation of proteolysisGO:00301622930.053
vasculature developmentGO:00019441810.053
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.052
protein modification by small protein conjugationGO:00324463420.051
enzyme linked receptor protein signaling pathwayGO:00071673030.050
negative regulation of proteolysisGO:00458611320.050
intracellular steroid hormone receptor signaling pathwayGO:0030518610.050
negative regulation of cell motilityGO:20001461040.050
protein export from nucleusGO:0006611290.050
atp metabolic processGO:00460341760.049
rig i signaling pathwayGO:003952970.047
regulation of interleukin 10 biosynthetic processGO:004507420.047
regulation of transferase activityGO:00513383550.047
regulation of establishment of protein localizationGO:00702012420.046
viral entry into host cellGO:0046718240.046
jak stat cascadeGO:0007259460.046
movement in environment of other organism involved in symbiotic interactionGO:0052192250.045
cellular response to abiotic stimulusGO:00712141170.045
Human
ribonucleoside monophosphate catabolic processGO:00091581580.045
regulation of viral entry into host cellGO:0046596170.044
interleukin 10 productionGO:0032613170.044
cellular response to interferon betaGO:003545860.043
Human
response to bacteriumGO:00096171440.043
Human
positive regulation of interleukin 4 productionGO:003275330.043
purine nucleotide biosynthetic processGO:0006164840.043
ribonucleoside catabolic processGO:00424544060.043
regulation of protein modification by small protein conjugation or removalGO:19033201070.042
interleukin 2 secretionGO:007097030.041
regulation of nucleocytoplasmic transportGO:0046822980.041
interferon beta productionGO:0032608230.041
Human
chemical homeostasisGO:00488783060.041
protein polyubiquitinationGO:00002091100.041
atp catabolic processGO:00062001570.040
entry into cell of other organism involved in symbiotic interactionGO:0051806250.040
glycoprotein metabolic processGO:00091001100.040
negative regulation of cell cycleGO:00457861930.040
Human
interleukin 13 biosynthetic processGO:004223110.039
response to oxygen containing compoundGO:19017003690.039
Human
cellular response to biotic stimulusGO:0071216710.039
cellular response to external stimulusGO:00714961110.039
Human
erythrocyte differentiationGO:0030218280.039
response to steroid hormoneGO:0048545800.039
ossificationGO:00015031210.039
positive regulation of response to external stimulusGO:0032103880.038
regulation of viral transcriptionGO:0046782340.038
purine ribonucleoside triphosphate metabolic processGO:00092054110.037
rna interferenceGO:001624640.037
purine nucleoside catabolic processGO:00061523980.037
negative regulation of phosphorus metabolic processGO:00105632670.037
regulation of interferon beta productionGO:0032648220.037
Human
positive regulation of apoptotic processGO:00430652460.036
Human
nuclear exportGO:0051168690.036
carbohydrate metabolic processGO:00059752070.036
positive regulation of viral processGO:0048524370.036
regulation of type i interferon productionGO:0032479260.036
Human
negative regulation of phosphorylationGO:00423261740.036
regulation of immune effector processGO:0002697910.036
entry into host cellGO:0030260250.036
negative regulation of protein kinase activityGO:0006469980.035
positive regulation of locomotionGO:00400171860.035
regulation of cell motilityGO:20001452990.035
regulation of actin filament based processGO:00329701410.034
regulation of macrophage fusionGO:003423910.034
purine containing compound biosynthetic processGO:0072522880.034
cellular macromolecule catabolic processGO:00442653800.034
positive regulation of cell differentiationGO:00455972110.033
regulation of interleukin 10 productionGO:0032653160.033
negative regulation of kinase activityGO:00336731060.033
metal ion transportGO:00300012720.033
cellular macromolecular complex assemblyGO:00346223240.032
regulation of cell differentiationGO:00455953930.032
glycoprotein biosynthetic processGO:0009101910.032
regulation of cell activationGO:00508651250.032
cellular response to interferon alphaGO:003545740.031
regulation of interleukin 2 secretionGO:190004020.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.031
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.030
response to estrogenGO:0043627470.030
response to tumor necrosis factorGO:0034612760.030
purine nucleotide catabolic processGO:00061954050.030
response to estradiolGO:0032355230.030
regulation of endothelial cell proliferationGO:0001936560.030
regulation of sequence specific dna binding transcription factor activityGO:00510902110.030
regulation of protein transportGO:00512232130.030
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.029
negative regulation of cell migrationGO:00303361020.029
response to organonitrogen compoundGO:00102431560.029
Human
protein k63 linked ubiquitinationGO:0070534310.029
nucleoside phosphate catabolic processGO:19012924120.029
cd8 positive alpha beta t cell differentiationGO:004337410.029
posttranscriptional gene silencing by rnaGO:0035194250.029
angiogenesisGO:00015251470.029
response to molecule of bacterial originGO:0002237820.029
Human
nucleoside monophosphate metabolic processGO:00091231910.029
purine containing compound catabolic processGO:00725234110.029
regulation of cytoskeleton organizationGO:00514931770.028
nucleoside triphosphate catabolic processGO:00091433940.028
cellular response to peptide hormone stimulusGO:0071375560.028
movement in host environmentGO:0052126250.028
hemopoiesisGO:00300971800.027
endosomal transportGO:00161971290.027
regulation of protein kinase activityGO:00458592890.027
negative regulation of cellular component movementGO:00512711060.027
positive regulation of proteolysisGO:00458621420.027
nucleoside catabolic processGO:00091644080.027
negative regulation of hydrolase activityGO:00513461820.027
glucose metabolic processGO:0006006450.026
negative regulation of leukocyte activationGO:0002695260.026
regulation of peptidase activityGO:00525471800.026
anatomical structure homeostasisGO:00602491000.026
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.026
regulation of fas signaling pathwayGO:190204420.026
negative regulation of peptidase activityGO:0010466910.026
regulation of intracellular transport of viral materialGO:190125220.026
purine nucleoside monophosphate metabolic processGO:00091261860.025
mitochondrion organizationGO:00070051560.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
epithelium developmentGO:00604292270.025
neurological system processGO:00508771630.025
protein acylationGO:00435431380.025
ribonucleoside monophosphate metabolic processGO:00091611870.025
positive regulation of cytokine biosynthetic processGO:0042108250.025
nuclear importGO:00511701060.025
regulation of type i interferon mediated signaling pathwayGO:006033890.025
innate immune response activating signal transductionGO:0002758480.024
regulation of immune responseGO:00507762010.024
Human
organonitrogen compound biosynthetic processGO:19015662000.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
positive regulation of multi organism processGO:0043902560.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
purine ribonucleotide catabolic processGO:00091544040.023
glycosyl compound catabolic processGO:19016584130.023
cellular response to hormone stimulusGO:00328701250.023
response to alcoholGO:0097305640.023
entry into other organism involved in symbiotic interactionGO:0051828250.023
cellular response to interleukin 6GO:0071354140.023
secretionGO:00469032540.023
negative regulation of interleukin 2 secretionGO:190004120.022
defense response to gram positive bacteriumGO:0050830290.022
regulation of cysteine type endopeptidase activityGO:20001161270.022
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.022
neuron projection regenerationGO:003110210.022
nucleoside triphosphate metabolic processGO:00091414220.022
negative regulation of protein modification processGO:00314002000.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.021
chromatin organizationGO:00063253510.021
nucleotide catabolic processGO:00091664080.021
negative regulation of cellular protein catabolic processGO:1903363380.021
positive regulation of hydrolase activityGO:00513453310.021
lipoprotein metabolic processGO:0042157420.021
secretion by cellGO:00329402260.021
regulation of cytokine biosynthetic processGO:0042035350.020
positive regulation of endopeptidase activityGO:0010950840.020
protein autoubiquitinationGO:0051865370.020
circulatory system developmentGO:00723592620.020
negative regulation of mitochondrial depolarizationGO:005190220.020
positive regulation of nf kappab transcription factor activityGO:0051092810.020
regulation of purine nucleotide metabolic processGO:19005422640.020
vesicle mediated transportGO:00161923710.019
negative regulation of cytokine productionGO:0001818820.019
negative regulation of protein phosphorylationGO:00019331400.019
cellular response to lipidGO:00713961270.019
leukocyte mediated immunityGO:0002443590.019
regulation of protein localizationGO:00328802960.019
immune response activating signal transductionGO:0002757900.019
regulation of protein processingGO:00706131500.018
regulation of cellular protein catabolic processGO:1903362960.018
viral release from host cellGO:0019076210.018
regulation of cellular component biogenesisGO:00440872810.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.018
interleukin 10 biosynthetic processGO:004209120.018
regulation of viral release from host cellGO:1902186200.018
response to interleukin 4GO:007067070.018
cellular response to growth hormone stimulusGO:0071378100.018
regulation of rig i signaling pathwayGO:003953560.018
i kappab kinase nf kappab signalingGO:00072491660.018
regulation of protein stabilityGO:0031647870.018
multi organism metabolic processGO:0044033410.017
regulation of lymphocyte proliferationGO:0050670640.017
ribonucleoprotein complex biogenesisGO:00226131160.017
regulation of cellular ketone metabolic processGO:0010565500.017
positive regulation of immune responseGO:00507781590.017
homeostasis of number of cellsGO:0048872400.017
negative regulation of intracellular transport of viral materialGO:190125320.017
negative regulation of programmed cell deathGO:00430693210.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
regulation of mononuclear cell proliferationGO:0032944650.016
interferon gamma productionGO:0032609390.016
negative regulation of cellular catabolic processGO:0031330830.016
positive regulation of defense responseGO:0031349870.016
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.016
positive regulation of cellular component biogenesisGO:00440891580.016
regulation of kinase activityGO:00435493140.016
actin cytoskeleton organizationGO:00300362070.016
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.016
negative regulation of protein maturationGO:19033181420.016
extracellular transportGO:000685840.016
purine ribonucleoside catabolic processGO:00461303980.016
negative regulation of catabolic processGO:00098951040.015
retrograde transport endosome to golgiGO:0042147450.015
ras protein signal transductionGO:0007265730.015
regulation of protein ubiquitinationGO:0031396950.015
negative regulation of cell activationGO:0050866330.015
lipoprotein biosynthetic processGO:0042158330.015
multi organism intracellular transportGO:1902583140.015
actin filament organizationGO:00070151280.015
tumor necrosis factor mediated signaling pathwayGO:0033209270.015
negative regulation of viral release from host cellGO:1902187120.015
response to dsrnaGO:0043331250.015
regulation of gene expression epigeneticGO:0040029730.015
positive regulation of cellular component organizationGO:00511303760.015
regulation of growthGO:00400081650.015
cellular response to organic cyclic compoundGO:00714071270.015
actin filament based processGO:00300292240.014
regulation of epithelial cell proliferationGO:00506781130.014
activation of innate immune responseGO:0002218550.014
negative regulation of viral entry into host cellGO:0046597120.014
detection of chemical stimulusGO:0009593550.014
response to peptideGO:1901652650.014
Human
detection of stimulus involved in sensory perceptionGO:0050906430.014
regenerationGO:003109940.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
adaptive immune responseGO:0002250490.014
Human
purine nucleoside triphosphate metabolic processGO:00091444120.014
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.014
cellular protein catabolic processGO:00442572610.014
positive regulation of nucleoside metabolic processGO:00459791860.014
ncrna processingGO:0034470830.014
multi organism localizationGO:1902579140.014
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.013
regulation of cytoplasmic transportGO:19036491490.013
cellular response to organonitrogen compoundGO:00714171240.013
negative regulation of transferase activityGO:00513481240.013
regulation of protein catabolic processGO:00421761550.013
regulation of t cell tolerance inductionGO:000266440.013
defense response to bacteriumGO:0042742630.013
nucleoside monophosphate catabolic processGO:00091251590.013
positive regulation of organelle organizationGO:00106381950.013
positive regulation of protein transportGO:00512221350.013
regulation of interleukin 13 productionGO:003265670.013
actin mediated cell contractionGO:0070252120.013
response to abiotic stimulusGO:00096283360.013
Human
purine ribonucleoside metabolic processGO:00461284370.013
fas signaling pathwayGO:003633730.012
rna processingGO:00063962550.012
regulation of cellular component sizeGO:0032535820.012
intracellular transport of virusGO:0075733140.012
cation transportGO:00068123310.012
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.012
posttranscriptional gene silencingGO:0016441250.012
cytokine biosynthetic processGO:0042089370.012
Mouse
negative regulation of leukocyte differentiationGO:1902106240.012
rna modificationGO:0009451270.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.012
regulation of ribonuclease activityGO:006070030.012
interleukin 2 biosynthetic processGO:004209470.012
protein modification by small protein removalGO:0070646920.012
establishment of tissue polarityGO:000716430.011
protein catabolic processGO:00301633250.011
determination of adult lifespanGO:000834020.011
carbohydrate homeostasisGO:0033500310.011
rna catabolic processGO:0006401710.011
immune system developmentGO:00025201950.011
negative regulation of cysteine type endopeptidase activityGO:2000117480.011
regulation of intracellular protein transportGO:00331571230.011
positive regulation of cellular catabolic processGO:00313312840.011
negative regulation of apoptotic processGO:00430663160.011
negative regulation of nf kappab transcription factor activityGO:0032088510.011
regulation of protein export from nucleusGO:0046825150.011
negative regulation of transportGO:00510511760.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
regulation of response to cytokine stimulusGO:0060759460.011
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathwayGO:003953170.011
negative regulation of protein catabolic processGO:0042177590.011
regulation of toll like receptor signaling pathwayGO:0034121170.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
negative regulation of cell deathGO:00605483450.011
ion homeostasisGO:00508012300.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
organophosphate biosynthetic processGO:00904071630.011
response to peptidoglycanGO:003249430.011
Human
mrna metabolic processGO:00160711750.011
positive regulation of protein complex assemblyGO:0031334860.010
negative regulation of protein ubiquitinationGO:0031397350.010
membrane organizationGO:00610242920.010
positive regulation of cell activationGO:0050867810.010
positive regulation of protein polymerizationGO:0032273450.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
protein monoubiquitinationGO:0006513390.010
ribonucleotide catabolic processGO:00092614050.010
single organism carbohydrate metabolic processGO:00447231930.010
positive regulation of osteoblast differentiationGO:0045669230.010
regulation of protein secretionGO:0050708860.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.010

IRF9 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.048
Human
bone diseaseDOID:0080001880.048
connective tissue diseaseDOID:651090.048
Human
disease of cellular proliferationDOID:145661740.027
Human
cancerDOID:1621670.027
Human
disease of metabolismDOID:00146672950.014
acquired metabolic diseaseDOID:0060158580.014
organ system cancerDOID:00506861640.011
Human