Homo sapiens

0 known processes

IRF8

interferon regulatory factor 8

(Aliases: H-ICSBP,IRF-8,ICSBP,ICSBP1)

IRF8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytokine productionGO:00018162470.753
Human Mouse
immune responseGO:00069553070.722
Human Mouse
regulation of cytokine productionGO:00018172320.628
Human Mouse
leukocyte activationGO:00453211640.601
cell activationGO:00017752130.526
immune system developmentGO:00025201950.489
Mouse
positive regulation of immune system processGO:00026842830.479
positive regulation of cytokine productionGO:00018191670.451
Human Mouse
lymphocyte activationGO:00466491330.441
immune effector processGO:00022521590.436
Human
response to other organismGO:00517072610.378
Human Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.374
Mouse
positive regulation of transportGO:00510503360.366
regulation of immune responseGO:00507762010.360
Human
response to bacteriumGO:00096171440.358
Human Mouse
response to oxygen containing compoundGO:19017003690.354
Human Mouse
response to biotic stimulusGO:00096072760.350
Human Mouse
regulation of cellular amino acid metabolic processGO:000652160.330
regulation of cellular ketone metabolic processGO:0010565500.326
secretionGO:00469032540.308
secretion by cellGO:00329402260.296
amine metabolic processGO:0009308440.295
response to external biotic stimulusGO:00432072610.293
Human Mouse
positive regulation of immune responseGO:00507781590.293
negative regulation of multicellular organismal processGO:00512413170.292
defense responseGO:00069523150.267
Human Mouse
cellular amino acid metabolic processGO:00065201160.260
innate immune responseGO:00450871780.259
hemopoiesisGO:00300971800.247
Mouse
regulation of cell migrationGO:00303342890.243
cellular ketone metabolic processGO:0042180800.243
regulation of cellular amine metabolic processGO:0033238110.241
negative regulation of immune system processGO:00026831360.229
cellular amine metabolic processGO:0044106410.226
positive regulation of cellular component organizationGO:00511303760.223
Mouse
positive regulation of programmed cell deathGO:00430682490.218
Human
cellular response to cytokine stimulusGO:00713451810.199
Human
lymphocyte proliferationGO:0046651700.186
small gtpase mediated signal transductionGO:0007264780.182
defense response to other organismGO:00985421290.176
Human Mouse
cellular response to oxygen containing compoundGO:19017012760.175
Mouse
response to cytokineGO:00340972320.171
Human
positive regulation of cellular amine metabolic processGO:003324070.170
regulation of response to external stimulusGO:00321012220.170
regulation of protein transportGO:00512232130.170
mapk cascadeGO:00001652880.167
cytokine mediated signaling pathwayGO:00192211090.166
regulation of secretionGO:00510461940.164
vesicle mediated transportGO:00161923710.163
Mouse
leukocyte differentiationGO:0002521980.163
regulation of leukocyte proliferationGO:0070663670.159
positive regulation of phosphorylationGO:00423273940.157
ras protein signal transductionGO:0007265730.153
activation of immune responseGO:00022531140.153
positive regulation of cell deathGO:00109422630.151
Human
regulation of secretion by cellGO:19035301770.150
regulation of cytokine secretionGO:0050707570.149
regulation of defense responseGO:00313471540.149
regulation of cell activationGO:00508651250.147
positive regulation of apoptotic processGO:00430652460.147
Human
leukocyte proliferationGO:0070661740.143
regulation of cell differentiationGO:00455953930.141
positive regulation of cell activationGO:0050867810.139
protein secretionGO:0009306980.137
regulation of protein localizationGO:00328802960.135
cell adhesionGO:00071553250.133
positive regulation of defense responseGO:0031349870.132
taxisGO:00423301570.132
regulation of cell cycleGO:00517263930.126
Human
cellular response to biotic stimulusGO:0071216710.124
Mouse
immune response regulating signaling pathwayGO:0002764970.121
divalent metal ion transportGO:00708381520.118
regulation of locomotionGO:00400123290.116
regulation of leukocyte activationGO:00026941150.116
response to virusGO:00096151260.114
Human
immune response activating signal transductionGO:0002757900.113
regulation of mononuclear cell proliferationGO:0032944650.112
positive regulation of locomotionGO:00400171860.111
regulation of protein secretionGO:0050708860.110
purine nucleoside triphosphate catabolic processGO:00091463920.110
negative regulation of cell proliferationGO:00082852280.109
biological adhesionGO:00226103310.106
rho protein signal transductionGO:0007266260.106
negative regulation of protein metabolic processGO:00512483910.100
regulation of mapk cascadeGO:00434082620.099
leukocyte mediated immunityGO:0002443590.099
negative regulation of cytokine productionGO:0001818820.098
cellular response to molecule of bacterial originGO:0071219620.094
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.093
cellular homeostasisGO:00197251960.091
nucleotide catabolic processGO:00091664080.090
interleukin 10 productionGO:0032613170.089
Human
regulation of establishment of protein localizationGO:00702012420.087
positive regulation of cellular component movementGO:00512721810.087
positive regulation of cell proliferationGO:00082843010.087
positive regulation of hydrolase activityGO:00513453310.085
t cell activationGO:0042110990.083
regulation of kinase activityGO:00435493140.082
gtp catabolic processGO:00061842370.081
pattern recognition receptor signaling pathwayGO:0002221480.081
cellular response to lipidGO:00713961270.080
Mouse
regulation of homeostatic processGO:00328441210.080
response to abiotic stimulusGO:00096283360.080
Human
adaptive immune responseGO:0002250490.079
Human
cellular chemical homeostasisGO:00550821800.077
regulation of transferase activityGO:00513383550.077
glycosyl compound catabolic processGO:19016584130.076
cation transportGO:00068123310.075
regulation of cell motilityGO:20001452990.074
purine nucleoside catabolic processGO:00061523980.073
positive regulation of response to external stimulusGO:0032103880.073
regulation of protein kinase activityGO:00458592890.072
positive regulation of developmental processGO:00510943140.072
positive regulation of cell migrationGO:00303351720.072
response to lipidGO:00339932060.072
Mouse
purine ribonucleotide catabolic processGO:00091544040.071
regulation of lymphocyte proliferationGO:0050670640.071
chemical homeostasisGO:00488783060.071
positive regulation of secretion by cellGO:19035321080.071
negative regulation of catalytic activityGO:00430863350.070
protein processingGO:00164852260.069
organophosphate catabolic processGO:00464344300.069
purine containing compound catabolic processGO:00725234110.069
nucleoside triphosphate metabolic processGO:00091414220.069
chemotaxisGO:00069351570.068
regulation of leukocyte migrationGO:0002685630.068
regulation of adaptive immune responseGO:0002819330.068
Human
purine nucleoside triphosphate metabolic processGO:00091444120.067
purine ribonucleoside metabolic processGO:00461284370.067
nucleoside triphosphate catabolic processGO:00091433940.067
metal ion homeostasisGO:00550651690.066
cell chemotaxisGO:00603261120.066
cellular response to abiotic stimulusGO:00712141170.066
Human
ribonucleotide catabolic processGO:00092614050.065
negative regulation of cellular component organizationGO:00511292350.064
mononuclear cell proliferationGO:0032943710.063
leukocyte chemotaxisGO:0030595760.063
ribonucleoside triphosphate catabolic processGO:00092033910.063
cytokine biosynthetic processGO:0042089370.062
Human
positive regulation of protein phosphorylationGO:00019343130.062
purine ribonucleoside catabolic processGO:00461303980.062
guanosine containing compound metabolic processGO:19010682440.061
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.061
negative regulation of programmed cell deathGO:00430693210.061
positive regulation of cell motilityGO:20001471770.060
eosinophil activation involved in immune responseGO:000227820.060
positive regulation of nucleotide metabolic processGO:00459812300.060
negative regulation of phosphorus metabolic processGO:00105632670.059
actin filament based processGO:00300292240.059
divalent inorganic cation transportGO:00725111580.059
positive regulation of purine nucleotide metabolic processGO:19005442270.059
negative regulation of cell deathGO:00605483450.059
regulation of intracellular transportGO:00323861950.059
cellular cation homeostasisGO:00300031630.058
ribonucleoside catabolic processGO:00424544060.058
cell developmentGO:00484683280.058
cell activation involved in immune responseGO:0002263300.058
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.058
negative regulation of immune responseGO:0050777400.057
regulation of nucleoside metabolic processGO:00091182090.057
negative regulation of hydrolase activityGO:00513461820.057
single organismal cell cell adhesionGO:00163371480.057
response to lipopolysaccharideGO:0032496700.056
Mouse
post embryonic developmentGO:000979120.056
regulation of nucleotide metabolic processGO:00061402690.056
negative regulation of cellular protein metabolic processGO:00322693530.055
inflammatory responseGO:0006954790.055
negative regulation of phosphate metabolic processGO:00459362670.055
positive regulation of gtp catabolic processGO:00331261660.055
regulation of cellular component biogenesisGO:00440872810.055
Mouse
guanosine containing compound catabolic processGO:19010692390.054
type i interferon productionGO:0032606270.052
Human
signal transduction by phosphorylationGO:00230142970.052
positive regulation of catabolic processGO:00098963100.052
regulation of vesicle mediated transportGO:00606271300.052
regulation of behaviorGO:0050795820.052
activation of innate immune responseGO:0002218550.052
regulation of calcium ion transport into cytosolGO:0010522330.052
regulation of innate immune responseGO:0045088970.051
cellular macromolecular complex assemblyGO:00346223240.051
divalent inorganic cation homeostasisGO:00725071360.051
calcium ion transportGO:00068161470.051
ribonucleoside triphosphate metabolic processGO:00091994120.051
regulation of anatomical structure morphogenesisGO:00226032860.051
regulation of lymphocyte activationGO:00512491030.051
negative regulation of homeostatic processGO:0032845590.051
response to molecule of bacterial originGO:0002237820.050
Human Mouse
positive regulation of innate immune responseGO:0045089790.050
cellular ion homeostasisGO:00068731680.050
cation homeostasisGO:00550801890.050
protein maturationGO:00516042330.050
positive regulation of cellular component biogenesisGO:00440891580.050
Mouse
cellular response to endogenous stimulusGO:00714953360.050
single organism cell adhesionGO:00986021790.049
chemokine productionGO:0032602320.049
purine ribonucleoside triphosphate catabolic processGO:00092073910.049
regulation of myeloid cell differentiationGO:0045637810.049
positive regulation of leukocyte proliferationGO:0070665480.049
regulation of metal ion transportGO:00109591200.049
regulation of leukocyte differentiationGO:1902105610.049
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
nucleoside phosphate catabolic processGO:19012924120.049
negative regulation of developmental processGO:00510932470.049
eosinophil activationGO:004330730.048
myeloid leukocyte activationGO:0002274340.048
leukocyte activation involved in immune responseGO:0002366300.048
protein oligomerizationGO:00512591730.048
leukocyte migrationGO:00509001070.047
positive regulation of secretionGO:00510471160.047
regulation of multi organism processGO:00439001570.047
Mouse
g protein coupled receptor signaling pathwayGO:00071862070.047
metal ion transportGO:00300012720.047
regulation of sequence specific dna binding transcription factor activityGO:00510902110.047
positive regulation of mononuclear cell proliferationGO:0032946470.046
purine nucleotide catabolic processGO:00061954050.046
regulation of gtpase activityGO:00430871800.046
regulation of protein serine threonine kinase activityGO:00719001790.046
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.045
maintenance of locationGO:00512351120.045
innate immune response activating signal transductionGO:0002758480.045
regulation of proteolysisGO:00301622930.045
negative regulation of apoptotic processGO:00430663160.044
nucleoside catabolic processGO:00091644080.044
positive regulation of nucleotide catabolic processGO:00308131850.044
myeloid leukocyte differentiationGO:0002573600.044
response to woundingGO:00096111680.044
female gamete generationGO:000729220.043
hormone secretionGO:0046879650.043
cellular response to lipopolysaccharideGO:0071222570.043
Mouse
cellular protein complex assemblyGO:00436231880.043
positive regulation of leukocyte activationGO:0002696800.043
regulation of immune effector processGO:0002697910.043
ion homeostasisGO:00508012300.042
cytoplasmic transportGO:00164823790.042
cytokine secretionGO:0050663640.041
positive regulation of protein transportGO:00512221350.041
positive regulation of protein kinase activityGO:00458601900.041
single organism cellular localizationGO:19025803320.040
apoptotic signaling pathwayGO:00971902680.040
peptidyl tyrosine modificationGO:00182121700.040
gtp metabolic processGO:00460392390.040
cellular metal ion homeostasisGO:00068751460.040
regulation of apoptotic signaling pathwayGO:20012331750.039
response to growth factorGO:00708482050.039
positive regulation of cellular catabolic processGO:00313312840.039
positive regulation of cytokine secretionGO:0050715420.039
mature dendritic cell differentiationGO:009702920.039
positive regulation of transferase activityGO:00513472270.039
regulation of protein complex assemblyGO:00432541470.039
Mouse
regulation of purine nucleotide metabolic processGO:19005422640.039
nitrogen compound transportGO:00717051910.038
cellular response to growth factor stimulusGO:00713631970.038
regulation of gtp catabolic processGO:00331241800.038
positive regulation of behaviorGO:0048520600.038
defense response to virusGO:0051607710.038
Human
regulation of t cell activationGO:0050863770.038
actin filament organizationGO:00070151280.038
sequestering of calcium ionGO:0051208170.038
multicellular organismal agingGO:001025930.038
regulation of peptidase activityGO:00525471800.037
positive regulation of purine nucleotide catabolic processGO:00331231850.037
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.037
regulation of protein processingGO:00706131500.037
positive regulation of kinase activityGO:00336742040.037
negative regulation of protein modification processGO:00314002000.037
sequestering of metal ionGO:0051238240.037
regulation of actin cytoskeleton organizationGO:00329561160.037
humoral immune responseGO:0006959490.036
regulation of cd8 positive alpha beta t cell activationGO:200118520.036
cellular divalent inorganic cation homeostasisGO:00725031280.036
regulation of leukocyte chemotaxisGO:0002688460.036
cellular lipid metabolic processGO:00442553030.036
positive regulation of gtpase activityGO:00435471660.036
behaviorGO:00076101120.036
b cell activationGO:0042113330.036
regulation of i kappab kinase nf kappab signalingGO:00431221620.036
regulation of chemokine productionGO:0032642310.035
regulation of nucleotide catabolic processGO:00308112050.035
calcium ion homeostasisGO:00550741220.035
cytokine metabolic processGO:0042107380.035
Human
t cell proliferationGO:0042098450.035
enzyme linked receptor protein signaling pathwayGO:00071673030.035
interleukin 1 beta productionGO:0032611220.035
cell cycle arrestGO:0007050710.035
Human
regulation of cellular component movementGO:00512703340.034
regulation of protein maturationGO:19033171500.034
antigen processing and presentationGO:0019882330.033
negative regulation of proteolysisGO:00458611320.033
regulation of calcium ion transportGO:0051924790.033
response to peptidoglycanGO:003249430.033
Human
eosinophil degranulationGO:004330820.033
regulation of ion transportGO:00432691890.032
oogenesisGO:004847720.032
regulation of ion homeostasisGO:2000021730.032
positive regulation of protein secretionGO:0050714600.032
regulation of peptidyl tyrosine phosphorylationGO:00507301080.032
positive regulation of lymphocyte activationGO:0051251730.032
positive regulation of cell differentiationGO:00455972110.032
endocytosisGO:00068971590.031
Mouse
determination of adult lifespanGO:000834020.031
chemokine c c motif ligand 21 signaling pathwayGO:003811610.031
cardiovascular system developmentGO:00723582620.031
regulation of interleukin 8 productionGO:0032677490.031
peptide transportGO:0015833740.031
cell morphogenesisGO:00009022960.031
vasculature developmentGO:00019441810.031
system processGO:00030083490.031
regulation of cytokine biosynthetic processGO:0042035350.031
Human
exocytosisGO:0006887710.031
lymphocyte differentiationGO:0030098350.031
regulation of purine nucleotide catabolic processGO:00331212050.030
extrinsic apoptotic signaling pathwayGO:00971911190.030
peptidyl tyrosine phosphorylationGO:00181081700.030
single organism membrane organizationGO:00448022680.030
regulation of ras gtpase activityGO:00323181280.030
regulation of rho protein signal transductionGO:0035023790.030
regulation of response to woundingGO:19030341010.030
response to nitrogen compoundGO:19016981840.030
Human
dendritic cell antigen processing and presentationGO:000246810.030
immune response activating cell surface receptor signaling pathwayGO:0002429450.029
production of molecular mediator of immune responseGO:0002440370.029
intracellular protein transportGO:00068862700.029
response to organic cyclic compoundGO:00140702040.029
regulation of small gtpase mediated signal transductionGO:00510561560.029
regulation of cellular response to stressGO:00801352440.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
peptide secretionGO:0002790510.029
regulation of chemotaxisGO:0050920740.029
negative regulation of cell differentiationGO:00455961710.029
azole transportGO:004511740.029
blood coagulationGO:0007596760.029
negative regulation of cell cycleGO:00457861930.029
Human
regulation of ras protein signal transductionGO:00465781550.029
actin cytoskeleton organizationGO:00300362070.029
regulation of actin filament based processGO:00329701410.029
carbohydrate derivative biosynthetic processGO:19011372070.028
lipid metabolic processGO:00066293810.028
interferon alpha biosynthetic processGO:004534940.028
coagulationGO:0050817780.028
negative regulation of transportGO:00510511760.028
symbiosis encompassing mutualism through parasitismGO:00444031560.027
Mouse
positive regulation of intracellular transportGO:00323881040.027
negative regulation of protein phosphorylationGO:00019331400.027
positive regulation of organelle organizationGO:00106381950.027
negative regulation of protein maturationGO:19033181420.027
epithelium developmentGO:00604292270.027
sensory perception of painGO:001923340.027
eosinophil mediated immunityGO:000244720.026
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.026
Mouse
jak stat cascadeGO:0007259460.026
regulation of eosinophil activationGO:190256620.026
wound healingGO:00420601150.026
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.026
neurogenesisGO:00220081690.026
regulation of anatomical structure sizeGO:00900661010.026
cellular calcium ion homeostasisGO:00068741170.026
lymphocyte mediated immunityGO:0002449480.026
negative regulation of leukocyte differentiationGO:1902106240.025
regulation of bindingGO:00510981110.025
positive regulation of nucleoside metabolic processGO:00459791860.025
dephosphorylationGO:00163112090.025
regulation of t cell proliferationGO:0042129420.025
positive regulation of mapk cascadeGO:00434101900.025
regulation of interleukin 10 productionGO:0032653160.025
Human
regulation of cytoskeleton organizationGO:00514931770.025
negative regulation of cellular amine metabolic processGO:003323930.025
response to fungusGO:000962040.025
negative regulation of apoptotic signaling pathwayGO:2001234970.025
myeloid cell differentiationGO:00300991170.025
Mouse
glycerolipid metabolic processGO:00464861070.025
negative regulation of protein processingGO:00109551420.025
positive regulation of cytoplasmic transportGO:1903651820.025
regulation of cysteine type endopeptidase activityGO:20001161270.024
positive regulation of stress activated mapk cascadeGO:0032874600.024
immune response regulating cell surface receptor signaling pathwayGO:0002768510.024
interleukin 2 productionGO:0032623200.024
Human
blood vessel developmentGO:00015681720.024
cell substrate adhesionGO:00315891320.024
transmembrane transportGO:00550853990.024
positive regulation of lymphocyte proliferationGO:0050671460.024
growthGO:00400072020.024
Mouse
cell cell signalingGO:00072671550.024
tumor necrosis factor superfamily cytokine productionGO:0071706450.024
negative regulation of locomotionGO:00400131180.024
negative regulation of phosphorylationGO:00423261740.023
regulation of endocytosisGO:0030100720.023
signal releaseGO:0023061700.023
positive regulation of t cell activationGO:0050870540.023
interferon beta productionGO:0032608230.023
Human
positive regulation of cytoskeleton organizationGO:0051495830.023
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068280.023
regulation of type i interferon productionGO:0032479260.023
Human
syncytium formation by plasma membrane fusionGO:000076820.023
regulation of cytoplasmic transportGO:19036491490.023
positive regulation of protein serine threonine kinase activityGO:00719021190.023
regulation of syncytium formation by plasma membrane fusionGO:006014220.022
organophosphate biosynthetic processGO:00904071630.022
regulation of peptide transportGO:0090087620.022
amide transportGO:0042886760.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.022
myeloid leukocyte migrationGO:0097529620.022
cytosolic calcium ion homeostasisGO:0051480890.022
regulation of interferon alpha biosynthetic processGO:004535440.022
membrane organizationGO:00610242920.022
negative regulation of cell activationGO:0050866330.022
neuromuscular junction developmentGO:000752830.022
single organism carbohydrate metabolic processGO:00447231930.022
t cell selectionGO:004505840.022
regulation of endopeptidase activityGO:00525481700.022
positive regulation of homeostatic processGO:0032846470.022
positive regulation of cytosolic calcium ion concentrationGO:0007204820.022
regulation of cell developmentGO:00602841610.022
negative regulation of protein transportGO:0051224750.021
mitotic cell cycle processGO:19030472860.021
positive regulation of proteolysisGO:00458621420.021
negative regulation of bindingGO:0051100570.021
regulation of erk1 and erk2 cascadeGO:0070372990.021
negative regulation of cell migrationGO:00303361020.021
calcium mediated signalingGO:0019722440.021
positive regulation of rho gtpase activityGO:0032321560.021
camp metabolic processGO:0046058610.021
regulation of hormone secretionGO:0046883570.021
regulation of dna metabolic processGO:00510521530.021
regulation of response to biotic stimulusGO:0002831550.021
negative regulation of growthGO:0045926970.021
Mouse
cytosolic calcium ion transportGO:0060401480.021
cellular response to dna damage stimulusGO:00069743790.021
regulation of protein stabilityGO:0031647870.021
reactive oxygen species metabolic processGO:0072593750.021
granulocyte migrationGO:0097530400.021
positive regulation of leukocyte chemotaxisGO:0002690380.021
interferon gamma productionGO:0032609390.021
Mouse
protein targetingGO:00066051870.021
regulation of hormone levelsGO:00108171250.021
nervous system developmentGO:00073992930.021
cell type specific apoptotic processGO:00972851250.020
negative regulation of multi organism processGO:0043901920.020
Mouse
regulation of protein bindingGO:0043393660.020
cellular macromolecule catabolic processGO:00442653800.020
stress activated mapk cascadeGO:0051403930.020
cellular component morphogenesisGO:00329893140.020
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.020
mitotic cell cycleGO:00002783260.020
positive regulation of t cell migrationGO:2000406130.020
regulation of cellular component sizeGO:0032535820.020
myeloid dendritic cell chemotaxisGO:000240830.020
response to alcoholGO:0097305640.020
protein localization to nucleusGO:00345041360.020
regulation of jnk cascadeGO:0046328730.020
neuron differentiationGO:00301821380.020
positive regulation of erk1 and erk2 cascadeGO:0070374750.020
myoblast fusionGO:000752010.020
inflammatory response to antigenic stimulusGO:000243740.020
peptide hormone secretionGO:0030072500.020
circulatory system developmentGO:00723592620.020
positive regulation of nf kappab transcription factor activityGO:0051092810.020
cell projection organizationGO:00300302520.020
purinergic nucleotide receptor signaling pathwayGO:003559040.019
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.019
stress activated protein kinase signaling cascadeGO:0031098940.019
negative regulation of cellular component movementGO:00512711060.019
regulation of stress activated mapk cascadeGO:0032872840.019
cell matrix adhesionGO:0007160850.019
i kappab kinase nf kappab signalingGO:00072491660.019
positive regulation of chemotaxisGO:0050921570.019
regulation of rho gtpase activityGO:0032319660.019
protein ubiquitinationGO:00165673140.019
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.019
positive regulation of calcium ion transportGO:0051928510.019
hindbrain developmentGO:003090230.019
epithelial cell proliferationGO:00506731280.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
zymogen activationGO:0031638700.018
positive regulation of interferon beta productionGO:0032728170.018
Human
negative regulation of response to external stimulusGO:0032102830.018
positive regulation of map kinase activityGO:0043406800.018
t cell differentiationGO:0030217290.018
regulation of interleukin 2 productionGO:0032663190.018
Human
t cell differentiation in thymusGO:003307740.018
interleukin 8 productionGO:0032637510.018
astrocyte chemotaxisGO:003570010.018
regulation of growthGO:00400081650.018
Mouse
interspecies interaction between organismsGO:00444191560.018
Mouse
regulation of interleukin 10 secretionGO:200117940.018
cyclic nucleotide metabolic processGO:0009187820.018
negative regulation of kinase activityGO:00336731060.018
angiogenesisGO:00015251470.018
regulation of actin polymerization or depolymerizationGO:0008064560.018
negative regulation of secretion by cellGO:1903531520.018
calcium ion transport into cytosolGO:0060402480.018

IRF8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.146
Human
cancerDOID:1621670.041
Human
organ system cancerDOID:00506861640.041
Human
disease of cellular proliferationDOID:145661740.041
Human
musculoskeletal system diseaseDOID:172230.035
Human
primary immunodeficiency diseaseDOID:612360.026
hematopoietic system diseaseDOID:741000.020