Homo sapiens

83 known processes

PANX1

pannexin 1

(Aliases: MRS1,MGC21309,PX1,UNQ2529)

PANX1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.094
cellular amino acid metabolic processGO:00065201160.089
positive regulation of cellular amino acid metabolic processGO:004576430.073
cellular amine metabolic processGO:0044106410.067
regulation of cellular ketone metabolic processGO:0010565500.065
purine ribonucleoside metabolic processGO:00461284370.065
cellular ketone metabolic processGO:0042180800.062
amine metabolic processGO:0009308440.060
regulation of cellular amino acid metabolic processGO:000652160.056
transmembrane transportGO:00550853990.055
locomotory behaviorGO:000762610.055
multicellular organismal agingGO:001025930.055
positive regulation of cellular amine metabolic processGO:003324070.053
determination of adult lifespanGO:000834020.052
regulation of cellular amine metabolic processGO:0033238110.051
nucleoside phosphate catabolic processGO:19012924120.050
ribonucleoside catabolic processGO:00424544060.048
nucleoside triphosphate metabolic processGO:00091414220.047
cell developmentGO:00484683280.047
female gamete generationGO:000729220.045
cation transportGO:00068123310.044
purine nucleotide catabolic processGO:00061954050.043
chemical homeostasisGO:00488783060.043
immune responseGO:00069553070.042
nucleoside triphosphate catabolic processGO:00091433940.042
positive regulation of transportGO:00510503360.041
organophosphate catabolic processGO:00464344300.041
regulation of cell differentiationGO:00455953930.040
purine ribonucleotide catabolic processGO:00091544040.040
nucleoside catabolic processGO:00091644080.040
regulation of transferase activityGO:00513383550.039
negative regulation of programmed cell deathGO:00430693210.039
ribonucleotide catabolic processGO:00092614050.039
ion transmembrane transportGO:00342203380.039
nucleotide catabolic processGO:00091664080.038
purine ribonucleoside catabolic processGO:00461303980.038
regulation of protein transportGO:00512232130.037
ribonucleoside triphosphate metabolic processGO:00091994120.037
gtp metabolic processGO:00460392390.037
purine nucleoside catabolic processGO:00061523980.037
mitotic cell cycleGO:00002783260.036
negative regulation of catalytic activityGO:00430863350.036
defense responseGO:00069523150.035
negative regulation of cell deathGO:00605483450.035
response to abiotic stimulusGO:00096283360.035
regulation of protein localizationGO:00328802960.034
positive regulation of phosphorylationGO:00423273940.034
regulation of response to external stimulusGO:00321012220.033
secretionGO:00469032540.033
oogenesisGO:004847720.033
purine nucleoside triphosphate catabolic processGO:00091463920.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
single organism cellular localizationGO:19025803320.033
guanosine containing compound catabolic processGO:19010692390.033
small gtpase mediated signal transductionGO:0007264780.033
protein o linked glycosylation via serineGO:001824230.033
cellular response to dna damage stimulusGO:00069743790.033
system processGO:00030083490.033
glycosyl compound catabolic processGO:19016584130.032
protein localization to organelleGO:00333652800.032
purine nucleoside triphosphate metabolic processGO:00091444120.031
apoptotic signaling pathwayGO:00971902680.031
regulation of kinase activityGO:00435493140.031
purine ribonucleoside triphosphate metabolic processGO:00092054110.031
guanosine containing compound metabolic processGO:19010682440.030
positive regulation of hydrolase activityGO:00513453310.030
purine containing compound catabolic processGO:00725234110.030
actin filament based processGO:00300292240.030
response to other organismGO:00517072610.030
regulation of cell motilityGO:20001452990.030
ribonucleoside triphosphate catabolic processGO:00092033910.029
response to oxygen containing compoundGO:19017003690.029
carbohydrate derivative biosynthetic processGO:19011372070.029
negative regulation of cellular protein metabolic processGO:00322693530.029
dephosphorylationGO:00163112090.029
protein modification by small protein conjugationGO:00324463420.029
cellular macromolecule catabolic processGO:00442653800.029
positive regulation of protein transportGO:00512221350.029
positive regulation of cell deathGO:00109422630.028
regulation of reactive oxygen species metabolic processGO:2000377410.028
cation homeostasisGO:00550801890.028
single organism membrane organizationGO:00448022680.028
nervous system developmentGO:00073992930.028
mitotic cell cycle processGO:19030472860.028
ras protein signal transductionGO:0007265730.028
regulation of establishment of protein localizationGO:00702012420.028
negative regulation of developmental processGO:00510932470.028
cell adhesionGO:00071553250.028
positive regulation of cellular component organizationGO:00511303760.027
oxidation reduction processGO:00551143960.027
regulation of cell migrationGO:00303342890.027
cytoplasmic transportGO:00164823790.027
positive regulation of cellular catabolic processGO:00313312840.027
lipid metabolic processGO:00066293810.027
regulation of cellular response to stressGO:00801352440.027
regulation of cellular component movementGO:00512703340.027
positive regulation of protein phosphorylationGO:00019343130.026
response to external biotic stimulusGO:00432072610.026
cation transmembrane transportGO:00986552380.026
cellular lipid metabolic processGO:00442553030.026
protein ubiquitinationGO:00165673140.026
regulation of locomotionGO:00400123290.026
metal ion transportGO:00300012720.026
cell projection organizationGO:00300302520.026
cellular response to oxygen containing compoundGO:19017012760.025
response to biotic stimulusGO:00096072760.025
regulation of protein kinase activityGO:00458592890.025
protein targetingGO:00066051870.025
reactive nitrogen species metabolic processGO:200105730.025
ion homeostasisGO:00508012300.025
positive regulation of apoptotic processGO:00430652460.025
reactive oxygen species metabolic processGO:0072593750.025
biological adhesionGO:00226103310.025
inorganic ion transmembrane transportGO:00986602310.024
innate immune responseGO:00450871780.024
positive regulation of programmed cell deathGO:00430682490.024
cell type specific apoptotic processGO:00972851250.024
regulation of cell cycleGO:00517263930.024
generation of neuronsGO:00486991520.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
negative regulation of protein metabolic processGO:00512483910.024
single organism carbohydrate metabolic processGO:00447231930.024
regulation of proteolysisGO:00301622930.024
positive regulation of catabolic processGO:00098963100.024
signal transduction by phosphorylationGO:00230142970.024
negative regulation of apoptotic processGO:00430663160.024
regulation of anatomical structure morphogenesisGO:00226032860.024
gtp catabolic processGO:00061842370.023
response to woundingGO:00096111680.023
mapk cascadeGO:00001652880.023
segmentationGO:003528240.023
intracellular protein transportGO:00068862700.023
neuromuscular junction developmentGO:000752830.023
cellular macromolecular complex assemblyGO:00346223240.023
positive regulation of immune system processGO:00026842830.023
organonitrogen compound biosynthetic processGO:19015662000.022
positive regulation of locomotionGO:00400171860.022
negative regulation of phosphorus metabolic processGO:00105632670.022
carbohydrate metabolic processGO:00059752070.022
cellular homeostasisGO:00197251960.022
protein catabolic processGO:00301633250.022
negative regulation of phosphate metabolic processGO:00459362670.022
cytokine productionGO:00018162470.022
sulfur compound metabolic processGO:00067901010.022
glycoprotein biosynthetic processGO:0009101910.022
vesicle mediated transportGO:00161923710.022
nitrogen compound transportGO:00717051910.022
adult locomotory behaviorGO:000834410.021
cell morphogenesisGO:00009022960.021
cellular component morphogenesisGO:00329893140.021
positive regulation of nucleotide metabolic processGO:00459812300.021
negative regulation of intracellular signal transductionGO:19025321830.021
response to cytokineGO:00340972320.021
positive regulation of cell migrationGO:00303351720.021
regulation of nucleotide catabolic processGO:00308112050.021
regulation of immune responseGO:00507762010.021
anion transportGO:00068201610.021
glycoprotein metabolic processGO:00091001100.021
metal ion homeostasisGO:00550651690.021
cellular chemical homeostasisGO:00550821800.021
divalent metal ion transportGO:00708381520.021
positive regulation of cell proliferationGO:00082843010.021
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.021
neurogenesisGO:00220081690.020
response to oxidative stressGO:00069791210.020
inorganic cation transmembrane transportGO:00986621940.020
regulation of nucleotide metabolic processGO:00061402690.020
neurological system processGO:00508771630.020
regulation of purine nucleotide metabolic processGO:19005422640.020
cell cycle phase transitionGO:00447701730.020
membrane organizationGO:00610242920.020
cellular protein catabolic processGO:00442572610.020
negative regulation of hydrolase activityGO:00513461820.020
circulatory system developmentGO:00723592620.020
negative regulation of multicellular organismal processGO:00512413170.020
i kappab kinase nf kappab signalingGO:00072491660.020
response to axon injuryGO:004867810.020
positive regulation of cell motilityGO:20001471770.020
positive regulation of cellular component movementGO:00512721810.020
hindbrain developmentGO:003090230.020
single organism cell adhesionGO:00986021790.020
mitotic cell cycle phase transitionGO:00447721620.019
response to lipidGO:00339932060.019
regulation of defense responseGO:00313471540.019
positive regulation of nucleotide catabolic processGO:00308131850.019
memoryGO:000761330.019
microtubule based processGO:00070172100.019
regulation of reactive oxygen species biosynthetic processGO:190342630.019
regulation of i kappab kinase nf kappab signalingGO:00431221620.019
establishment of protein localization to organelleGO:00725941720.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
vasodilationGO:004231140.019
regulation of secretion by cellGO:19035301770.019
regulation of apoptotic signaling pathwayGO:20012331750.019
reactive oxygen species biosynthetic processGO:190340940.019
positive regulation of nucleoside metabolic processGO:00459791860.019
response to organic cyclic compoundGO:00140702040.019
regulation of cellular component biogenesisGO:00440872810.019
regulation of gtpase activityGO:00430871800.019
regenerationGO:003109940.019
protein maturationGO:00516042330.019
cellular cation homeostasisGO:00300031630.019
regulation of cell cycle processGO:00105642660.019
blastoderm segmentationGO:000735020.018
negative regulation of cell proliferationGO:00082852280.018
regulation of cytokine productionGO:00018172320.018
negative regulation of cell cycleGO:00457861930.018
nucleoside monophosphate metabolic processGO:00091231910.018
cellular protein complex assemblyGO:00436231880.018
ubiquitin dependent protein catabolic processGO:00065112060.018
negative regulation of cellular component organizationGO:00511292350.018
regulation of mitotic cell cycleGO:00073461890.018
divalent inorganic cation transportGO:00725111580.018
positive regulation of synaptic transmissionGO:005080640.018
negative regulation of phosphorylationGO:00423261740.018
regulation of intracellular transportGO:00323861950.018
cellular response to endogenous stimulusGO:00714953360.018
small molecule biosynthetic processGO:00442831570.018
cellular ion homeostasisGO:00068731680.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
sequestering of metal ionGO:0051238240.018
rho protein signal transductionGO:0007266260.017
g protein coupled receptor signaling pathwayGO:00071862070.017
atp metabolic processGO:00460341760.017
secretion by cellGO:00329402260.017
circadian behaviorGO:004851220.017
regulation of intracellular protein transportGO:00331571230.017
regulation of purine nucleotide catabolic processGO:00331212050.017
modification dependent protein catabolic processGO:00199412090.017
positive regulation of transferase activityGO:00513472270.017
maintenance of locationGO:00512351120.017
motor neuron axon guidanceGO:000804520.017
limbic system developmentGO:002176130.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
rhythmic behaviorGO:000762220.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
epithelium developmentGO:00604292270.017
positive regulation of kinase activityGO:00336742040.017
regulation of mapk cascadeGO:00434082620.017
regulation of synaptic plasticityGO:004816730.017
divalent inorganic cation homeostasisGO:00725071360.017
cardiac muscle cell contractionGO:008600340.017
neuron projection developmentGO:00311751060.017
photoreceptor cell differentiationGO:004653020.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
hematopoietic or lymphoid organ developmentGO:00485341860.016
endomembrane system organizationGO:00102561960.016
cell growthGO:00160491600.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
modification dependent macromolecule catabolic processGO:00436322120.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
mitochondrion organizationGO:00070051560.016
positive regulation of intracellular protein transportGO:0090316760.016
compound eye developmentGO:004874910.016
neuroblast proliferationGO:000740540.016
response to growth factorGO:00708482050.016
regulation of homeostatic processGO:00328441210.016
syncytium formation by plasma membrane fusionGO:000076820.016
negative regulation of protein modification processGO:00314002000.016
oocyte developmentGO:004859910.016
response to radiationGO:00093141510.016
oligosaccharide biosynthetic processGO:000931230.016
positive regulation of cytokine productionGO:00018191670.016
protein processingGO:00164852260.016
posttranscriptional regulation of gene expressionGO:00106082130.016
oocyte differentiationGO:000999420.015
negative regulation of transportGO:00510511760.015
single organismal cell cell adhesionGO:00163371480.015
stem cell divisionGO:001714520.015
response to fungusGO:000962040.015
regulation of nucleoside metabolic processGO:00091182090.015
spermatid differentiationGO:004851540.015
calcium ion transportGO:00068161470.015
regulation of ion transportGO:00432691890.015
protein oligomerizationGO:00512591730.015
positive regulation of protein kinase activityGO:00458601900.015
positive regulation of developmental processGO:00510943140.015
sequestering of calcium ionGO:0051208170.015
organophosphate biosynthetic processGO:00904071630.015
regulation of cytoskeleton organizationGO:00514931770.015
neuron differentiationGO:00301821380.015
protein homooligomerizationGO:00512601000.015
chemotaxisGO:00069351570.015
histone modificationGO:00165702510.015
associative learningGO:000830610.015
response to nitrogen compoundGO:19016981840.015
cellular response to growth factor stimulusGO:00713631970.015
nucleocytoplasmic transportGO:00069131760.015
regulation of cell projection organizationGO:00313441070.015
cellular metal ion homeostasisGO:00068751460.015
immune effector processGO:00022521590.015
regulation of protein serine threonine kinase activityGO:00719001790.015
cellular response to external stimulusGO:00714961110.015
neuron projection regenerationGO:003110210.015
microtubule cytoskeleton organizationGO:00002261760.015
spermatid developmentGO:000728640.015
positive regulation of intracellular transportGO:00323881040.015
macromolecule glycosylationGO:0043413630.014
regulation of ion transmembrane transportGO:00347651320.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
cellular response to cytokine stimulusGO:00713451810.014
epithelial cell differentiationGO:00308551410.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
protein importGO:00170381300.014
cell divisionGO:00513011680.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
positive regulation of gtp catabolic processGO:00331261660.014
morphogenesis of embryonic epitheliumGO:001633140.014
positive regulation of cell differentiationGO:00455972110.014
proteasomal protein catabolic processGO:00104981760.014
regulation of cell adhesionGO:00301551660.014
organ formationGO:004864530.014
actin cytoskeleton organizationGO:00300362070.014
circulatory system processGO:00030131130.014
organic hydroxy compound metabolic processGO:19016151470.014
rna processingGO:00063962550.014
cerebellum developmentGO:002154920.014
peripheral nervous system developmentGO:000742220.014
cell activationGO:00017752130.014
cellular response to lipidGO:00713961270.014
response to inorganic substanceGO:00100351270.014
regulation of transmembrane transportGO:00347621390.014
cofactor metabolic processGO:0051186870.014
immune system developmentGO:00025201950.014
neuron developmentGO:00486661130.013
nucleotide biosynthetic processGO:00091651090.013
cellular response to oxidative stressGO:0034599850.013
peptidyl tyrosine modificationGO:00182121700.013
actin mediated cell contractionGO:0070252120.013
regulation of peptidase activityGO:00525471800.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
metencephalon developmentGO:002203720.013
hemopoiesisGO:00300971800.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
anterior posterior axis specificationGO:000994820.013
anterior posterior axis specification embryoGO:000859520.013
protein localization to membraneGO:00726571600.013
protein localization to nucleusGO:00345041360.013
regulation of cell morphogenesisGO:00226041530.013
actin filament based movementGO:0030048170.013
regulation of protein catabolic processGO:00421761550.013
nuclear transportGO:00511691790.013
atp catabolic processGO:00062001570.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
lipid biosynthetic processGO:00086101770.013
somatic muscle developmentGO:000752510.013
inner ear morphogenesisGO:004247240.013
positive regulation of gtpase activityGO:00435471660.013
rna interferenceGO:001624640.013
negative regulation of reactive oxygen species metabolic processGO:2000378110.013
regulation of neural precursor cell proliferationGO:200017740.013
monocarboxylic acid metabolic processGO:00327871850.013
regulation of cytoplasmic transportGO:19036491490.013
negative regulation of cell cycle processGO:00109481210.013
positive regulation of mapk cascadeGO:00434101900.013
single organism reproductive processGO:0044702980.013
myoblast fusionGO:000752010.013
axon regenerationGO:003110310.013
negative regulation of response to external stimulusGO:0032102830.013
growthGO:00400072020.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
cardiovascular system developmentGO:00723582620.013
regulation of protein processingGO:00706131500.013
negative regulation of proteolysisGO:00458611320.013
muscle system processGO:0003012810.013
leukocyte activationGO:00453211640.013
regulation of metal ion transportGO:00109591200.013
peptidyl tyrosine phosphorylationGO:00181081700.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of secretionGO:00510461940.013
cellular response to nutrient levelsGO:0031669690.013
regulation of ras protein signal transductionGO:00465781550.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
response to hormoneGO:00097251750.012
regulation of dna metabolic processGO:00510521530.012
regulation of gtp catabolic processGO:00331241800.012
regulation of meiotic cell cycleGO:005144540.012
regulation of multi organism processGO:00439001570.012
lipid transportGO:0006869900.012
ribonucleotide biosynthetic processGO:0009260810.012
regulation of cell developmentGO:00602841610.012
epithelial cell proliferationGO:00506731280.012
positive regulation of organelle organizationGO:00106381950.012
purine ribonucleotide biosynthetic processGO:0009152790.012
cellular response to nitrogen compoundGO:19016991440.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
chromatin organizationGO:00063253510.012
central nervous system developmentGO:00074171230.012
apoptotic mitochondrial changesGO:0008637570.012
defense response to other organismGO:00985421290.012
peptidyl serine modificationGO:00182091060.012
tissue migrationGO:00901301190.012
regulation of bindingGO:00510981110.012
regulation of endopeptidase activityGO:00525481700.012
protein secretionGO:0009306980.012
positive regulation of cellular component biogenesisGO:00440891580.012
response to organonitrogen compoundGO:00102431560.012
nucleoside monophosphate catabolic processGO:00091251590.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
chromatin modificationGO:00165682980.012
nerve developmentGO:002167540.012
protein o linked glycosylation via threonineGO:001824340.012
negative regulation of cellular amine metabolic processGO:003323930.012
response to extracellular stimulusGO:0009991850.012
regulation of protein complex assemblyGO:00432541470.012
regulation of transporter activityGO:0032409820.012
negative regulation of protein phosphorylationGO:00019331400.012
salivary gland morphogenesisGO:000743540.012
purine containing compound biosynthetic processGO:0072522880.012
behaviorGO:00076101120.012
covalent chromatin modificationGO:00165692540.012
glycosylationGO:0070085710.012
negative regulation of cell differentiationGO:00455961710.012
regulation of protein maturationGO:19033171500.012
wound healingGO:00420601150.012
organic acid biosynthetic processGO:0016053970.012
cell chemotaxisGO:00603261120.012
response to increased oxygen levelsGO:003629640.012
visual behaviorGO:000763220.012
blood circulationGO:00080151130.012
negative regulation of locomotionGO:00400131180.012
negative regulation of transferase activityGO:00513481240.011
cell fate determinationGO:000170930.011
organelle assemblyGO:00709251760.011
negative regulation of cell migrationGO:00303361020.011
epithelial cell migrationGO:00106311190.011
response to bacteriumGO:00096171440.011
establishment of protein localization to membraneGO:00901501210.011
cellular response to abiotic stimulusGO:00712141170.011
regulation of transmembrane transporter activityGO:0022898740.011
tissue regenerationGO:004224630.011
cell part morphogenesisGO:00329901370.011
negative regulation of blood pressureGO:004577630.011
wnt signaling pathwayGO:00160551560.011
positive regulation of ras gtpase activityGO:00323201170.011
interspecies interaction between organismsGO:00444191560.011
regulation of cell cycle phase transitionGO:19019871260.011
nucleoside phosphate biosynthetic processGO:19012931090.011
cellular response to extracellular stimulusGO:0031668720.011
positive regulation of immune responseGO:00507781590.011
taxisGO:00423301570.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
regulation of ras gtpase activityGO:00323181280.011
cellular modified amino acid metabolic processGO:0006575640.011
positive regulation of gliogenesisGO:001401540.011
cell projection morphogenesisGO:00488581290.011
negative regulation of organelle organizationGO:00106391260.011
t cell differentiation in thymusGO:003307740.011
regulation of protein secretionGO:0050708860.011
neurotransmitter secretionGO:000726940.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
negative regulation of protein processingGO:00109551420.011
regulation of response to woundingGO:19030341010.011
regulation of actin filament based processGO:00329701410.011
defense response to fungusGO:005083240.011
negative regulation of catabolic processGO:00098951040.011
tripartite regional subdivisionGO:000735120.011
positive regulation of ion transportGO:0043270870.011
embryonic epithelial tube formationGO:000183840.011
negative regulation of cellular component movementGO:00512711060.011
ribose phosphate biosynthetic processGO:0046390820.011
myosin filament organizationGO:003103320.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
positive regulation of secretionGO:00510471160.011
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
epithelium migrationGO:00901321190.011
sensory perception of painGO:001923340.011
ossificationGO:00015031210.011
lung alveolus developmentGO:004828640.011

PANX1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.029
disease of metabolismDOID:00146672950.029
cancerDOID:1621670.024
disease of cellular proliferationDOID:145661740.024
inherited metabolic disorderDOID:6552420.022
sensory system diseaseDOID:00501552030.022
nervous system diseaseDOID:8634310.022
organ system cancerDOID:00506861640.020
central nervous system diseaseDOID:3311860.018
connective tissue diseaseDOID:651090.017
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
retinal diseaseDOID:56791180.015
immune system diseaseDOID:29141550.015
bone diseaseDOID:0080001880.014
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
brain diseaseDOID:936730.012
retinal degenerationDOID:8466890.012
neurodegenerative diseaseDOID:12891020.011
acquired metabolic diseaseDOID:0060158580.011