Homo sapiens

22 known processes

KLHL13

kelch-like 13 (Drosophila)

(Aliases: BKLHD2,MGC74791,FLJ10262)

KLHL13 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule catabolic processGO:00442653800.125
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.096
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.082
Human
protein processingGO:00164852260.081
modification dependent macromolecule catabolic processGO:00436322120.077
Human
post embryonic developmentGO:000979120.074
protein maturationGO:00516042330.073
cell divisionGO:00513011680.072
negative regulation of protein metabolic processGO:00512483910.070
negative regulation of cellular protein metabolic processGO:00322693530.067
proteasomal protein catabolic processGO:00104981760.065
Human
cellular protein catabolic processGO:00442572610.058
Human
cellular amino acid metabolic processGO:00065201160.057
ubiquitin dependent protein catabolic processGO:00065112060.053
Human
regulation of cell cycleGO:00517263930.052
protein ubiquitinationGO:00165673140.052
regulation of proteolysisGO:00301622930.052
protein catabolic processGO:00301633250.050
Human
cellular amine metabolic processGO:0044106410.050
amine metabolic processGO:0009308440.049
regulation of cell cycle processGO:00105642660.048
negative regulation of protein maturationGO:19033181420.048
regulation of protein processingGO:00706131500.046
protein modification by small protein removalGO:0070646920.046
regulation of cellular amine metabolic processGO:0033238110.046
regulation of cellular amino acid metabolic processGO:000652160.045
cytokinesisGO:0000910960.044
cellular ketone metabolic processGO:0042180800.043
regulation of protein maturationGO:19033171500.040
cellular response to dna damage stimulusGO:00069743790.040
cell morphogenesisGO:00009022960.039
modification dependent protein catabolic processGO:00199412090.039
Human
positive regulation of cellular amine metabolic processGO:003324070.038
regulation of anatomical structure morphogenesisGO:00226032860.038
negative regulation of protein processingGO:00109551420.038
cellular component morphogenesisGO:00329893140.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
negative regulation of proteolysisGO:00458611320.036
negative regulation of catabolic processGO:00098951040.036
mitotic cell cycle processGO:19030472860.036
multicellular organismal agingGO:001025930.036
protein polyubiquitinationGO:00002091100.035
Human
regulation of cellular ketone metabolic processGO:0010565500.035
mitotic cell cycleGO:00002783260.034
oogenesisGO:004847720.034
lipid metabolic processGO:00066293810.034
determination of adult lifespanGO:000834020.033
positive regulation of cellular component organizationGO:00511303760.033
negative regulation of cell cycleGO:00457861930.033
female gamete generationGO:000729220.032
protein modification by small protein conjugationGO:00324463420.032
nervous system developmentGO:00073992930.032
regulation of cell morphogenesisGO:00226041530.032
cell cycle phase transitionGO:00447701730.031
protein localization to organelleGO:00333652800.031
posttranscriptional regulation of gene expressionGO:00106082130.031
positive regulation of phosphorylationGO:00423273940.030
positive regulation of protein phosphorylationGO:00019343130.030
single organism cellular localizationGO:19025803320.030
locomotory behaviorGO:000762610.029
negative regulation of cellular component organizationGO:00511292350.029
regulation of cell cycle phase transitionGO:19019871260.028
biological adhesionGO:00226103310.028
negative regulation of cell deathGO:00605483450.028
regulation of protein catabolic processGO:00421761550.027
negative regulation of mitotic cell cycle phase transitionGO:1901991850.027
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.027
regulation of protein localizationGO:00328802960.027
neuromuscular junction developmentGO:000752830.027
mitotic cell cycle phase transitionGO:00447721620.027
purine ribonucleoside metabolic processGO:00461284370.027
segmentationGO:003528240.027
regulation of mitotic cell cycleGO:00073461890.027
regulation of mitotic cell cycle phase transitionGO:19019901180.027
memoryGO:000761330.026
chemical homeostasisGO:00488783060.026
cell adhesionGO:00071553250.026
cell cycle checkpointGO:00000751170.026
nucleoside phosphate catabolic processGO:19012924120.026
purine nucleotide catabolic processGO:00061954050.026
negative regulation of proteasomal protein catabolic processGO:1901799320.026
response to abiotic stimulusGO:00096283360.025
negative regulation of programmed cell deathGO:00430693210.025
cytoplasmic transportGO:00164823790.025
ras protein signal transductionGO:0007265730.025
cellular lipid metabolic processGO:00442553030.025
system processGO:00030083490.024
negative regulation of catalytic activityGO:00430863350.024
negative regulation of cellular catabolic processGO:0031330830.024
small gtpase mediated signal transductionGO:0007264780.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
positive regulation of hydrolase activityGO:00513453310.024
ribonucleoside catabolic processGO:00424544060.024
anterior posterior axis specificationGO:000994820.024
blastoderm segmentationGO:000735020.024
purine ribonucleoside catabolic processGO:00461303980.024
positive regulation of transportGO:00510503360.024
transmembrane transportGO:00550853990.024
regulation of cellular protein catabolic processGO:1903362960.024
regenerationGO:003109940.024
regulation of cellular response to stressGO:00801352440.023
regulation of transferase activityGO:00513383550.023
mapk cascadeGO:00001652880.023
glycosyl compound catabolic processGO:19016584130.023
purine containing compound catabolic processGO:00725234110.023
actin filament based processGO:00300292240.023
purine ribonucleotide catabolic processGO:00091544040.023
response to oxygen containing compoundGO:19017003690.023
regulation of protein kinase activityGO:00458592890.023
signal transduction by phosphorylationGO:00230142970.022
nucleotide catabolic processGO:00091664080.022
cell projection organizationGO:00300302520.022
immune responseGO:00069553070.022
ion homeostasisGO:00508012300.022
ribonucleotide catabolic processGO:00092614050.022
negative regulation of apoptotic processGO:00430663160.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
defense responseGO:00069523150.022
regulation of locomotionGO:00400123290.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
negative regulation of phosphorus metabolic processGO:00105632670.022
adult locomotory behaviorGO:000834410.021
purine nucleoside catabolic processGO:00061523980.021
hindbrain developmentGO:003090230.021
organophosphate catabolic processGO:00464344300.021
innate immune responseGO:00450871780.021
positive regulation of immune system processGO:00026842830.021
regulation of cellular component movementGO:00512703340.021
peripheral nervous system developmentGO:000742220.021
negative regulation of multicellular organismal processGO:00512413170.021
negative regulation of phosphate metabolic processGO:00459362670.021
negative regulation of protein catabolic processGO:0042177590.021
cellular response to endogenous stimulusGO:00714953360.020
associative learningGO:000830610.020
negative regulation of cell cycle processGO:00109481210.020
positive regulation of transferase activityGO:00513472270.020
carbohydrate derivative biosynthetic processGO:19011372070.020
positive regulation of catabolic processGO:00098963100.020
secretionGO:00469032540.020
negative regulation of cell proliferationGO:00082852280.020
morphogenesis of embryonic epitheliumGO:001633140.020
rho protein signal transductionGO:0007266260.020
nucleoside triphosphate catabolic processGO:00091433940.020
neurogenesisGO:00220081690.020
regulation of kinase activityGO:00435493140.020
positive regulation of protein kinase activityGO:00458601900.019
regulation of mapk cascadeGO:00434082620.019
negative regulation of mitotic cell cycleGO:00459301020.019
nucleoside catabolic processGO:00091644080.019
cellular response to oxygen containing compoundGO:19017012760.019
nucleoside triphosphate metabolic processGO:00091414220.019
regulation of establishment of protein localizationGO:00702012420.019
vesicle mediated transportGO:00161923710.019
response to growth factorGO:00708482050.019
organonitrogen compound biosynthetic processGO:19015662000.019
negative regulation of organelle organizationGO:00106391260.019
positive regulation of cell proliferationGO:00082843010.019
small molecule biosynthetic processGO:00442831570.019
positive regulation of cellular catabolic processGO:00313312840.019
monocarboxylic acid metabolic processGO:00327871850.019
negative regulation of protein modification processGO:00314002000.018
cation transportGO:00068123310.018
matingGO:000761810.018
metal ion transportGO:00300012720.018
glial cell migrationGO:000834740.018
neuron differentiationGO:00301821380.018
positive regulation of synaptic transmissionGO:005080640.018
embryonic epithelial tube formationGO:000183840.018
cell fate determinationGO:000170930.018
negative regulation of cellular protein catabolic processGO:1903363380.018
secretion by cellGO:00329402260.018
response to biotic stimulusGO:00096072760.018
spermatid differentiationGO:004851540.018
regulation of secretionGO:00510461940.018
lipid biosynthetic processGO:00086101770.018
dephosphorylationGO:00163112090.018
ion transmembrane transportGO:00342203380.018
oxidation reduction processGO:00551143960.018
cell developmentGO:00484683280.018
regulation of cellular component biogenesisGO:00440872810.018
regulation of cell motilityGO:20001452990.018
positive regulation of cell cycleGO:00457871400.018
negative regulation of cell cycle phase transitionGO:1901988890.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
microtubule based processGO:00070172100.017
Human
regulation of cytokine productionGO:00018172320.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.017
positive regulation of cell deathGO:00109422630.017
motor neuron axon guidanceGO:000804520.017
regulation of cell migrationGO:00303342890.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
mitotic cell cycle checkpointGO:0007093680.017
positive regulation of nucleotide metabolic processGO:00459812300.017
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of secretion by cellGO:19035301770.017
inner ear morphogenesisGO:004247240.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
positive regulation of kinase activityGO:00336742040.017
anterior posterior axis specification embryoGO:000859520.017
regulation of cell differentiationGO:00455953930.017
spinal cord developmentGO:002151040.017
epithelium developmentGO:00604292270.016
apoptotic signaling pathwayGO:00971902680.016
cation transmembrane transportGO:00986552380.016
reactive oxygen species biosynthetic processGO:190340940.016
chromatin organizationGO:00063253510.016
neurotransmitter secretionGO:000726940.016
nerve developmentGO:002167540.016
intracellular protein transportGO:00068862700.016
cytokine productionGO:00018162470.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of mitosisGO:0007088630.016
response to other organismGO:00517072610.016
cellular chemical homeostasisGO:00550821800.016
reactive nitrogen species metabolic processGO:200105730.016
regulation of response to external stimulusGO:00321012220.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
cation homeostasisGO:00550801890.016
histone modificationGO:00165702510.016
photoreceptor cell differentiationGO:004653020.016
maintenance of locationGO:00512351120.016
positive regulation of nucleoside metabolic processGO:00459791860.016
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of protein serine threonine kinase activityGO:00719001790.015
positive regulation of mapk cascadeGO:00434101900.015
neurological system processGO:00508771630.015
organ formationGO:004864530.015
neuroblast proliferationGO:000740540.015
regulation of synaptic plasticityGO:004816730.015
compound eye developmentGO:004874910.015
inorganic ion transmembrane transportGO:00986602310.015
regulation of cytoskeleton organizationGO:00514931770.015
rhythmic behaviorGO:000762220.015
inorganic cation transmembrane transportGO:00986621940.015
regulation of microtubule based processGO:0032886740.015
Human
wnt signaling pathwayGO:00160551560.015
negative regulation of phosphorylationGO:00423261740.015
organic hydroxy compound metabolic processGO:19016151470.015
oocyte differentiationGO:000999420.015
regulation of cell growthGO:00015581350.015
regulation of ion transportGO:00432691890.015
negative regulation of developmental processGO:00510932470.015
chromatin modificationGO:00165682980.015
regulation of proteasomal protein catabolic processGO:0061136870.015
cellular macromolecular complex assemblyGO:00346223240.015
response to axon injuryGO:004867810.015
circulatory system developmentGO:00723592620.015
regulation of protein stabilityGO:0031647870.015
response to external biotic stimulusGO:00432072610.015
spermatid developmentGO:000728640.014
anatomical structure homeostasisGO:00602491000.014
microtubule cytoskeleton organizationGO:00002261760.014
endomembrane system organizationGO:00102561960.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
positive regulation of developmental processGO:00510943140.014
chromosome segregationGO:00070591140.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of nucleotide metabolic processGO:00061402690.014
single organism membrane organizationGO:00448022680.014
organelle fissionGO:00482851490.014
negative regulation of intracellular signal transductionGO:19025321830.014
reactive oxygen species metabolic processGO:0072593750.014
cell activationGO:00017752130.014
response to nitrogen compoundGO:19016981840.014
organophosphate biosynthetic processGO:00904071630.014
oocyte developmentGO:004859910.014
regulation of intracellular transportGO:00323861950.014
cardiac muscle cell contractionGO:008600340.014
morphogenesis of a polarized epitheliumGO:000173830.014
syncytium formation by plasma membrane fusionGO:000076820.014
guanosine containing compound catabolic processGO:19010692390.014
cell projection morphogenesisGO:00488581290.014
regulation of nucleoside metabolic processGO:00091182090.014
protein deubiquitinationGO:0016579790.014
tripartite regional subdivisionGO:000735120.014
regulation of apoptotic signaling pathwayGO:20012331750.014
guanosine containing compound metabolic processGO:19010682440.014
regulation of neural precursor cell proliferationGO:200017740.014
single organism carbohydrate metabolic processGO:00447231930.014
salivary gland morphogenesisGO:000743540.014
mitotic nuclear divisionGO:00070671190.014
metencephalon developmentGO:002203720.014
cell part morphogenesisGO:00329901370.014
gtp metabolic processGO:00460392390.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
epithelial cell differentiationGO:00308551410.014
response to lipidGO:00339932060.014
negative regulation of transportGO:00510511760.014
response to cytokineGO:00340972320.014
gtp catabolic processGO:00061842370.014
regulation of protein transportGO:00512232130.014
membrane organizationGO:00610242920.014
response to fungusGO:000962040.014
positive regulation of cell cycle processGO:00900681060.014
stem cell divisionGO:001714520.014
divalent inorganic cation homeostasisGO:00725071360.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
cardiovascular system developmentGO:00723582620.013
peptidyl tyrosine phosphorylationGO:00181081700.013
carbohydrate metabolic processGO:00059752070.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of growthGO:00400081650.013
neural tube formationGO:000184130.013
cellular metal ion homeostasisGO:00068751460.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
protein stabilizationGO:0050821640.013
positive regulation of apoptotic processGO:00430652460.013
positive regulation of secretion by cellGO:19035321080.013
monovalent inorganic cation transportGO:00156721280.013
nucleoside monophosphate catabolic processGO:00091251590.013
sequestering of metal ionGO:0051238240.013
regulation of gtpase activityGO:00430871800.013
organic acid biosynthetic processGO:0016053970.013
circadian behaviorGO:004851220.013
positive regulation of programmed cell deathGO:00430682490.013
regulation of vesicle mediated transportGO:00606271300.013
cellular cation homeostasisGO:00300031630.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
actin mediated cell contractionGO:0070252120.013
negative regulation of protein phosphorylationGO:00019331400.013
sleepGO:003043120.013
peptidyl tyrosine modificationGO:00182121700.013
g protein coupled receptor signaling pathwayGO:00071862070.013
cellular ion homeostasisGO:00068731680.013
protein targetingGO:00066051870.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
tissue regenerationGO:004224630.013
visual behaviorGO:000763220.013
actin filament based movementGO:0030048170.013
cell growthGO:00160491600.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.013
positive regulation of cell migrationGO:00303351720.013
divalent inorganic cation transportGO:00725111580.013
multi organism cellular processGO:00447641560.013
positive regulation of locomotionGO:00400171860.013
lung alveolus developmentGO:004828640.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
response to woundingGO:00096111680.013
covalent chromatin modificationGO:00165692540.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
endocytosisGO:00068971590.013
response to hormoneGO:00097251750.012
mitotic sister chromatid separationGO:0051306180.012
rna processingGO:00063962550.012
rna interferenceGO:001624640.012
positive regulation of secretionGO:00510471160.012
positive regulation of cellular component movementGO:00512721810.012
thymus developmentGO:004853830.012
sensory perception of painGO:001923340.012
synaptic vesicle endocytosisGO:004848820.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
immune system developmentGO:00025201950.012
dna repairGO:00062811980.012
cell substrate adhesionGO:00315891320.012
cerebellum developmentGO:002154920.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
positive regulation of cell differentiationGO:00455972110.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of cell divisionGO:00513021160.012
somatic muscle developmentGO:000752510.012
sequestering of calcium ionGO:0051208170.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
metal ion homeostasisGO:00550651690.012
cellular homeostasisGO:00197251960.012
regulation of neurotransmitter secretionGO:004692830.012
regulation of chromosome organizationGO:00330441030.012
central nervous system developmentGO:00074171230.012
nuclear transportGO:00511691790.012
protein homooligomerizationGO:00512601000.012
limbic system developmentGO:002176130.012
generation of neuronsGO:00486991520.012
establishment of planar polarityGO:000173630.012
regulation of cell developmentGO:00602841610.012
single organism cell adhesionGO:00986021790.012
positive regulation of cytokine productionGO:00018191670.012
long term memoryGO:000761620.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
cell projection assemblyGO:00300311260.012
behavioral response to ethanolGO:004814920.012
somitogenesisGO:000175620.012
activation of protein kinase activityGO:0032147900.012
cell morphogenesis involved in differentiationGO:00009041440.012
mitotic sister chromatid segregationGO:0000070530.012
tube closureGO:006060630.012
nitrogen compound transportGO:00717051910.012
regulation of endopeptidase activityGO:00525481700.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
fatty acid metabolic processGO:00066311150.012
interspecies interaction between organismsGO:00444191560.012
primary neural tube formationGO:001402030.012
somatic stem cell divisionGO:004810310.012
somatic stem cell maintenanceGO:003501940.012
neural tube closureGO:000184330.011
positive regulation of organelle organizationGO:00106381950.011
regulation of dna metabolic processGO:00510521530.011
t cell differentiation in thymusGO:003307740.011
regulation of cell adhesionGO:00301551660.011
alcohol metabolic processGO:00060661140.011
response to oxidative stressGO:00069791210.011
neuron projection developmentGO:00311751060.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
regulation of ras protein signal transductionGO:00465781550.011
response to bacteriumGO:00096171440.011
negative regulation of transferase activityGO:00513481240.011
response to organic cyclic compoundGO:00140702040.011
stress activated mapk cascadeGO:0051403930.011
epithelial cell proliferationGO:00506731280.011
regulation of multi organism processGO:00439001570.011
glycoprotein metabolic processGO:00091001100.011
mitochondrion organizationGO:00070051560.011
sister chromatid segregationGO:0000819540.011
anion transportGO:00068201610.011
regulation of nucleotide catabolic processGO:00308112050.011
pituitary gland developmentGO:002198320.011
cranial nerve developmentGO:002154540.011
regulation of peptidase activityGO:00525471800.011
regulation of immune responseGO:00507762010.011
positive regulation of cell motilityGO:20001471770.011
reproductive processGO:00224141060.011
establishment of protein localization to organelleGO:00725941720.011
myoblast fusionGO:000752010.011
nucleus localizationGO:005164710.011
sulfur compound metabolic processGO:00067901010.011
chemotaxisGO:00069351570.011
response to radiationGO:00093141510.011
positive regulation of protein transportGO:00512221350.011
specification of organ identityGO:001009230.011
negative regulation of locomotionGO:00400131180.011
nucleotide biosynthetic processGO:00091651090.011
positive regulation of proteolysisGO:00458621420.011
regulation of cytoplasmic transportGO:19036491490.011
nucleocytoplasmic transportGO:00069131760.011
neuron developmentGO:00486661130.011
startle responseGO:000196430.011
prostate gland developmentGO:003085030.011
melanin metabolic processGO:000658210.011
response to inorganic substanceGO:00100351270.011
actin cytoskeleton organizationGO:00300362070.011
tissue migrationGO:00901301190.011
establishment of tissue polarityGO:000716430.011
regulation of intracellular protein transportGO:00331571230.011
engulfment of apoptotic cellGO:004365220.011
neuron projection regenerationGO:003110210.011
regulation of nuclear divisionGO:0051783650.011
positive regulation of immune responseGO:00507781590.011
regulation of purine nucleotide catabolic processGO:00331212050.011
positive regulation of gtp catabolic processGO:00331261660.011
cellular response to cytokine stimulusGO:00713451810.011
regulation of meiosisGO:004002030.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
leukocyte activationGO:00453211640.011
protein localization to membraneGO:00726571600.011
developmental programmed cell deathGO:001062330.011
monocarboxylic acid biosynthetic processGO:0072330670.010
response to organonitrogen compoundGO:00102431560.010
regulation of gtp catabolic processGO:00331241800.010
epithelium migrationGO:00901321190.010
divalent metal ion transportGO:00708381520.010
sensory perception of smellGO:000760820.010
cell differentiation in spinal cordGO:002151510.010
regulation of homeostatic processGO:00328441210.010
negative regulation of cellular component movementGO:00512711060.010
regulation of ras gtpase activityGO:00323181280.010
negative regulation of cell migrationGO:00303361020.010
cellular response to lipidGO:00713961270.010

KLHL13 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.034
nervous system diseaseDOID:8634310.032
central nervous system diseaseDOID:3311860.032
inherited metabolic disorderDOID:6552420.026
musculoskeletal system diseaseDOID:172230.026
sensory system diseaseDOID:00501552030.024
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
brain diseaseDOID:936730.018
neurodegenerative diseaseDOID:12891020.016
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
myopathyDOID:4231040.015
cardiovascular system diseaseDOID:12871060.014
immune system diseaseDOID:29141550.014
retinal diseaseDOID:56791180.014
connective tissue diseaseDOID:651090.014
bone diseaseDOID:0080001880.012
disease of mental healthDOID:150700.011
retinal degenerationDOID:8466890.011
carbohydrate metabolic disorderDOID:2978550.011