Homo sapiens

48 known processes

KLKB1

kallikrein B, plasma (Fletcher factor) 1

(Aliases: PPK,KLK3)

KLKB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.172
chemical homeostasisGO:00488783060.130
ion homeostasisGO:00508012300.122
lipid metabolic processGO:00066293810.107
regulation of cellular amine metabolic processGO:0033238110.099
cellular amino acid metabolic processGO:00065201160.096
monocarboxylic acid metabolic processGO:00327871850.093
oxidation reduction processGO:00551143960.086
cation transmembrane transportGO:00986552380.084
positive regulation of transportGO:00510503360.083
regulation of cellular ketone metabolic processGO:0010565500.080
cellular amine metabolic processGO:0044106410.079
system processGO:00030083490.077
amine metabolic processGO:0009308440.076
regulation of cellular amino acid metabolic processGO:000652160.074
transmembrane transportGO:00550853990.073
response to oxygen containing compoundGO:19017003690.072
organic anion transportGO:00157111030.071
protein processingGO:00164852260.069
post embryonic developmentGO:000979120.068
ion transmembrane transportGO:00342203380.066
cation homeostasisGO:00550801890.065
cation transportGO:00068123310.064
protein maturationGO:00516042330.061
cellular lipid metabolic processGO:00442553030.061
metal ion transportGO:00300012720.059
positive regulation of cellular amino acid metabolic processGO:004576430.056
defense responseGO:00069523150.055
anion transportGO:00068201610.055
positive regulation of phosphorylationGO:00423273940.054
cellular response to endogenous stimulusGO:00714953360.053
immune responseGO:00069553070.052
regulation of hormone levelsGO:00108171250.052
metal ion homeostasisGO:00550651690.050
regulation of response to external stimulusGO:00321012220.049
negative regulation of protein metabolic processGO:00512483910.049
positive regulation of immune system processGO:00026842830.045
cellular response to oxygen containing compoundGO:19017012760.045
response to abiotic stimulusGO:00096283360.045
positive regulation of cellular amine metabolic processGO:003324070.045
negative regulation of catalytic activityGO:00430863350.044
multicellular organismal agingGO:001025930.043
regulation of protein processingGO:00706131500.043
inorganic cation transmembrane transportGO:00986621940.042
cellular homeostasisGO:00197251960.041
determination of adult lifespanGO:000834020.040
nucleoside triphosphate metabolic processGO:00091414220.040
locomotory behaviorGO:000762610.040
negative regulation of cellular protein metabolic processGO:00322693530.040
organonitrogen compound biosynthetic processGO:19015662000.040
g protein coupled receptor signaling pathwayGO:00071862070.039
cytoplasmic transportGO:00164823790.039
negative regulation of protein maturationGO:19033181420.039
positive regulation of cellular component organizationGO:00511303760.038
regulation of protein maturationGO:19033171500.038
purine ribonucleoside metabolic processGO:00461284370.038
cellular chemical homeostasisGO:00550821800.038
cellular cation homeostasisGO:00300031630.038
inorganic ion transmembrane transportGO:00986602310.038
nitrogen compound transportGO:00717051910.037
negative regulation of proteolysisGO:00458611320.037
response to lipidGO:00339932060.037
fatty acid metabolic processGO:00066311150.037
9 cis retinoic acid metabolic processGO:004290510.036
positive regulation of catabolic processGO:00098963100.036
response to hormoneGO:00097251750.036
divalent inorganic cation homeostasisGO:00725071360.036
purine containing compound catabolic processGO:00725234110.036
secretionGO:00469032540.036
ribonucleotide catabolic processGO:00092614050.034
response to cytokineGO:00340972320.034
regulation of proteolysisGO:00301622930.034
regulation of cellular component movementGO:00512703340.034
response to woundingGO:00096111680.034
membrane organizationGO:00610242920.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
female gamete generationGO:000729220.033
cellular metal ion homeostasisGO:00068751460.033
regulation of cytokine productionGO:00018172320.033
regulation of immune responseGO:00507762010.032
lipid biosynthetic processGO:00086101770.032
negative regulation of hydrolase activityGO:00513461820.032
nucleotide catabolic processGO:00091664080.031
positive regulation of cellular component movementGO:00512721810.031
small gtpase mediated signal transductionGO:0007264780.031
memoryGO:000761330.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
nucleoside catabolic processGO:00091644080.031
purine nucleotide catabolic processGO:00061954050.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
ribonucleoside catabolic processGO:00424544060.031
regulation of nucleotide metabolic processGO:00061402690.031
nucleoside triphosphate catabolic processGO:00091433940.031
single organism cellular localizationGO:19025803320.030
regenerationGO:003109940.030
Rat
purine nucleoside catabolic processGO:00061523980.030
organic hydroxy compound metabolic processGO:19016151470.030
organic acid biosynthetic processGO:0016053970.030
nucleoside phosphate catabolic processGO:19012924120.030
sensory perception of smellGO:000760820.030
regulation of body fluid levelsGO:0050878990.030
purine nucleoside triphosphate metabolic processGO:00091444120.029
positive regulation of nucleotide metabolic processGO:00459812300.029
regulation of secretion by cellGO:19035301770.029
innate immune responseGO:00450871780.029
ras protein signal transductionGO:0007265730.029
response to inorganic substanceGO:00100351270.029
regulation of phospholipase c activating g protein coupled receptor signaling pathwayGO:190073610.029
response to external biotic stimulusGO:00432072610.029
negative regulation of protein processingGO:00109551420.029
oogenesisGO:004847720.029
regulation of response to woundingGO:19030341010.028
regulation of protein localizationGO:00328802960.028
positive regulation of cellular catabolic processGO:00313312840.028
organophosphate catabolic processGO:00464344300.028
hemostasisGO:0007599760.028
wound healingGO:00420601150.028
carbohydrate derivative biosynthetic processGO:19011372070.028
reactive oxygen species metabolic processGO:0072593750.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
urate transportGO:001574730.027
purine ribonucleotide catabolic processGO:00091544040.027
positive regulation of mapk cascadeGO:00434101900.027
regulation of secretionGO:00510461940.027
positive regulation of fibrinolysisGO:005191940.027
coagulationGO:0050817780.027
negative regulation of cellular component organizationGO:00511292350.027
calcium ion homeostasisGO:00550741220.027
secretion by cellGO:00329402260.027
regulation of locomotionGO:00400123290.027
single organism membrane organizationGO:00448022680.026
cellular calcium ion homeostasisGO:00068741170.026
carboxylic acid biosynthetic processGO:0046394970.026
positive regulation of synaptic transmissionGO:005080640.026
regulation of cellular response to stressGO:00801352440.026
purine ribonucleoside catabolic processGO:00461303980.026
actin filament based processGO:00300292240.026
protein localization to organelleGO:00333652800.026
associative learningGO:000830610.026
sulfur compound metabolic processGO:00067901010.026
negative regulation of multicellular organismal processGO:00512413170.026
regulation of establishment of protein localizationGO:00702012420.026
biological adhesionGO:00226103310.026
positive regulation of protein phosphorylationGO:00019343130.025
urea metabolic processGO:001962730.025
regulation of reactive oxygen species metabolic processGO:2000377410.025
cellular ion homeostasisGO:00068731680.025
rhythmic behaviorGO:000762220.025
apoptotic signaling pathwayGO:00971902680.025
maintenance of locationGO:00512351120.025
neurological system processGO:00508771630.024
monovalent inorganic cation transportGO:00156721280.024
response to biotic stimulusGO:00096072760.024
rho protein signal transductionGO:0007266260.024
cofactor metabolic processGO:0051186870.024
regulation of purine nucleotide metabolic processGO:19005422640.024
positive regulation of secretionGO:00510471160.024
response to organic cyclic compoundGO:00140702040.024
glycosyl compound catabolic processGO:19016584130.024
regulation of protein kinase activityGO:00458592890.024
regulation of cellular component biogenesisGO:00440872810.024
carbohydrate metabolic processGO:00059752070.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
single organism carbohydrate metabolic processGO:00447231930.024
intracellular protein transportGO:00068862700.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
response to nitrogen compoundGO:19016981840.024
regulation of defense responseGO:00313471540.023
cytokine productionGO:00018162470.023
regulation of mapk cascadeGO:00434082620.023
matingGO:000761810.023
positive regulation of cytosolic calcium ion concentrationGO:0007204820.023
coenzyme metabolic processGO:0006732650.023
circadian behaviorGO:004851220.023
cellular divalent inorganic cation homeostasisGO:00725031280.023
lipid localizationGO:00108761060.023
regulation of ion transportGO:00432691890.023
mapk cascadeGO:00001652880.023
positive regulation of hydrolase activityGO:00513453310.023
negative regulation of phosphate metabolic processGO:00459362670.023
neuromuscular junction developmentGO:000752830.022
regulation of peptidase activityGO:00525471800.022
regulation of cell motilityGO:20001452990.022
positive regulation of locomotionGO:00400171860.022
vesicle mediated transportGO:00161923710.022
cell adhesionGO:00071553250.022
regulation of anatomical structure morphogenesisGO:00226032860.022
regulation of protein transportGO:00512232130.022
reactive oxygen species biosynthetic processGO:190340940.022
cellular macromolecular complex assemblyGO:00346223240.022
negative regulation of phosphorus metabolic processGO:00105632670.022
organic acid transportGO:0015849650.021
alcohol metabolic processGO:00060661140.021
spermatid differentiationGO:004851540.021
regulation of transferase activityGO:00513383550.021
positive regulation of secretion by cellGO:19035321080.021
regulation of kinase activityGO:00435493140.021
segmentationGO:003528240.021
regulation of endopeptidase activityGO:00525481700.021
carboxylic acid transportGO:0046942630.021
inflammatory responseGO:0006954790.021
positive regulation of cell migrationGO:00303351720.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
signal transduction by phosphorylationGO:00230142970.020
monocarboxylic acid biosynthetic processGO:0072330670.020
negative regulation of cellular amine metabolic processGO:003323930.020
multicellular organismal response to stressGO:003355510.020
cell developmentGO:00484683280.020
divalent inorganic cation transportGO:00725111580.020
mitotic cell cycleGO:00002783260.020
protein targetingGO:00066051870.020
regulation of cell cycleGO:00517263930.020
lipid transportGO:0006869900.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
cellular macromolecule catabolic processGO:00442653800.019
positive regulation of organelle organizationGO:00106381950.019
cytosolic calcium ion homeostasisGO:0051480890.019
cell cell signalingGO:00072671550.019
small molecule catabolic processGO:0044282920.019
multi organism cellular processGO:00447641560.019
small molecule biosynthetic processGO:00442831570.019
organophosphate biosynthetic processGO:00904071630.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
immune effector processGO:00022521590.019
reactive nitrogen species metabolic processGO:200105730.019
response to organonitrogen compoundGO:00102431560.019
response to drugGO:0042493810.019
negative regulation of peptidase activityGO:0010466910.019
protein localization to membraneGO:00726571600.019
positive regulation of transferase activityGO:00513472270.019
negative regulation of endopeptidase activityGO:0010951840.019
peptidyl tyrosine phosphorylationGO:00181081700.019
amide transportGO:0042886760.019
dephosphorylationGO:00163112090.019
positive regulation of cytokine productionGO:00018191670.019
divalent metal ion transportGO:00708381520.019
positive regulation of cell proliferationGO:00082843010.018
epoxygenase p450 pathwayGO:001937330.018
positive regulation of kinase activityGO:00336742040.018
activation of immune responseGO:00022531140.018
gtp metabolic processGO:00460392390.018
positive regulation of ion transportGO:0043270870.018
peripheral nervous system developmentGO:000742220.018
regulation of reactive oxygen species biosynthetic processGO:190342630.018
negative regulation of intracellular signal transductionGO:19025321830.018
cellular response to nitrogen compoundGO:19016991440.018
cyclic nucleotide metabolic processGO:0009187820.018
protein catabolic processGO:00301633250.018
cellular response to dna damage stimulusGO:00069743790.018
cellular protein complex assemblyGO:00436231880.018
detection of stimulusGO:0051606850.018
quinone catabolic processGO:190166220.018
sensory perceptionGO:00076001030.018
negative regulation of programmed cell deathGO:00430693210.018
positive regulation of cell motilityGO:20001471770.018
atp metabolic processGO:00460341760.018
organic acid catabolic processGO:0016054710.018
response to other organismGO:00517072610.018
guanosine containing compound catabolic processGO:19010692390.017
negative regulation of response to woundingGO:1903035470.017
blastoderm segmentationGO:000735020.017
sequestering of calcium ionGO:0051208170.017
regulation of behaviorGO:0050795820.017
adult locomotory behaviorGO:000834410.017
symbiosis encompassing mutualism through parasitismGO:00444031560.017
positive regulation of cell deathGO:00109422630.017
spermatid developmentGO:000728640.017
alkaloid metabolic processGO:000982040.017
positive regulation of immune responseGO:00507781590.017
ketone catabolic processGO:004218230.017
positive regulation of developmental processGO:00510943140.017
vitamin e metabolic processGO:004236010.017
viral processGO:00160321460.017
mitotic cell cycle processGO:19030472860.017
detection of chemical stimulus involved in sensory perception of smellGO:005091120.017
cell activationGO:00017752130.017
regulation of cytoskeleton organizationGO:00514931770.017
negative regulation of cell deathGO:00605483450.017
carboxylic acid catabolic processGO:0046395710.017
nucleoside phosphate biosynthetic processGO:19012931090.017
nucleotide biosynthetic processGO:00091651090.017
sequestering of metal ionGO:0051238240.017
hindbrain developmentGO:003090230.017
regulation of cell cycle processGO:00105642660.017
guanosine containing compound metabolic processGO:19010682440.017
behaviorGO:00076101120.017
protein oligomerizationGO:00512591730.017
steroid metabolic processGO:0008202940.017
response to hypoxiaGO:0001666960.017
negative regulation of protein modification processGO:00314002000.017
cell morphogenesisGO:00009022960.017
oocyte developmentGO:004859910.017
response to oxygen levelsGO:00704821000.017
gtp catabolic processGO:00061842370.017
regulation of intracellular transportGO:00323861950.016
interspecies interaction between organismsGO:00444191560.016
muscle contractionGO:0006936730.016
positive regulation of cellular component biogenesisGO:00440891580.016
nervous system developmentGO:00073992930.016
cellular component morphogenesisGO:00329893140.016
positive regulation of protein transportGO:00512221350.016
mitochondrion organizationGO:00070051560.016
glycoprotein metabolic processGO:00091001100.016
regulation of nucleoside metabolic processGO:00091182090.016
endomembrane system organizationGO:00102561960.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of feeding behaviorGO:006025930.016
purine containing compound biosynthetic processGO:0072522880.016
hormone transportGO:0009914680.016
cellular response to hormone stimulusGO:00328701250.016
viral life cycleGO:00190581320.016
positive regulation of reactive oxygen species metabolic processGO:2000379240.016
cellular response to organonitrogen compoundGO:00714171240.016
cellular response to organic cyclic compoundGO:00714071270.016
regulation of coagulationGO:0050818440.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
positive regulation of programmed cell deathGO:00430682490.016
glycerolipid metabolic processGO:00464861070.016
response to axon injuryGO:004867810.016
syncytium formation by plasma membrane fusionGO:000076820.016
lipid catabolic processGO:0016042840.016
nuclear transportGO:00511691790.016
neurotransmitter secretionGO:000726940.016
lipid modificationGO:0030258840.016
morphogenesis of a polarized epitheliumGO:000173830.016
negative regulation of transportGO:00510511760.016
actin cytoskeleton organizationGO:00300362070.016
microtubule based processGO:00070172100.015
regulation of protein complex assemblyGO:00432541470.015
sleepGO:003043120.015
tissue regenerationGO:004224630.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of protein kinase activityGO:00458601900.015
potassium ion transportGO:0006813620.015
cell projection organizationGO:00300302520.015
nitrogen cycle metabolic processGO:007194130.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
regulation of membrane potentialGO:0042391950.015
metencephalon developmentGO:002203720.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
nucleoside monophosphate metabolic processGO:00091231910.015
negative regulation of apoptotic processGO:00430663160.015
regulation of purine nucleotide catabolic processGO:00331212050.015
positive regulation of vasoconstrictionGO:004590730.015
cell growthGO:00160491600.015
drinking behaviorGO:004275610.015
cardiovascular system developmentGO:00723582620.015
regulation of synaptic plasticityGO:004816730.015
regulation of ion transmembrane transportGO:00347651320.015
growthGO:00400072020.015
positive regulation of intracellular transportGO:00323881040.015
calcium ion transportGO:00068161470.015
regulation of transmission of nerve impulseGO:005196920.015
oocyte differentiationGO:000999420.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of cell adhesionGO:00301551660.015
regulation of growthGO:00400081650.015
negative regulation of phosphorylationGO:00423261740.015
response to activityGO:001482300.015
motor neuron axon guidanceGO:000804520.015
peptide transportGO:0015833740.015
long chain fatty acid metabolic processGO:0001676300.015
cerebellum developmentGO:002154920.015
establishment of protein localization to membraneGO:00901501210.015
nucleocytoplasmic transportGO:00069131760.015
positive regulation of nucleoside metabolic processGO:00459791860.015
circadian sleep wake cycleGO:004274520.015
muscle system processGO:0003012810.015
vitamin k catabolic processGO:004237720.015
second messenger mediated signalingGO:0019932780.014
cellular response to lipidGO:00713961270.014
regulation of gtpase activityGO:00430871800.014
regulation of cytoplasmic transportGO:19036491490.014
salivary gland morphogenesisGO:000743540.014
blood circulationGO:00080151130.014
regulation of dna metabolic processGO:00510521530.014
response to bacteriumGO:00096171440.014
regulation of nucleotide catabolic processGO:00308112050.014
photoreceptor cell differentiationGO:004653020.014
regulation of transmembrane transportGO:00347621390.014
long term memoryGO:000761620.014
protein secretionGO:0009306980.014
regulation of cell differentiationGO:00455953930.014
regulation of cell migrationGO:00303342890.014
sensory perception of painGO:001923340.014
ribose phosphate biosynthetic processGO:0046390820.014
cellular response to abiotic stimulusGO:00712141170.014
response to metal ionGO:0010038840.014
phenylpropanoid metabolic processGO:000969830.014
morphogenesis of embryonic epitheliumGO:001633140.014
response to fungusGO:000962040.014
tripartite regional subdivisionGO:000735120.014
cardiac muscle cell contractionGO:008600340.014
response to salt stressGO:000965130.014
protein modification by small protein conjugationGO:00324463420.014
menaquinone metabolic processGO:000923330.014
regulation of protein catabolic processGO:00421761550.014
regulation of neurotransmitter secretionGO:004692830.014
purine ribonucleotide biosynthetic processGO:0009152790.014
negative regulation of organelle organizationGO:00106391260.014
peptidyl tyrosine modificationGO:00182121700.014
protein ubiquitinationGO:00165673140.014
cell substrate adhesionGO:00315891320.014
rna processingGO:00063962550.014
regulation of cell morphogenesisGO:00226041530.014
cellular response to cytokine stimulusGO:00713451810.014
naphthalene metabolic processGO:001893110.014
circulatory system developmentGO:00723592620.014
covalent chromatin modificationGO:00165692540.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
sodium ion transmembrane transportGO:0035725590.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
chemotaxisGO:00069351570.013
cellular protein catabolic processGO:00442572610.013
endocytosisGO:00068971590.013
post embryonic organ developmentGO:004856910.013
circulatory system processGO:00030131130.013
defense response to fungusGO:005083240.013
positive regulation of sequestering of triglycerideGO:001089030.013
protein localization to nucleusGO:00345041360.013
response to oxidative stressGO:00069791210.013
histone modificationGO:00165702510.013
cell projection assemblyGO:00300311260.013
regulation of blood coagulationGO:0030193420.013
alpha ketoglutarate transportGO:001574210.013
membrane hyperpolarizationGO:006008110.013
positive regulation of nucleotide catabolic processGO:00308131850.013
negative regulation of icosanoid secretionGO:003230420.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
sensory perception of chemical stimulusGO:0007606380.013
nerve developmentGO:002167540.013
chromatin organizationGO:00063253510.013
stress activated mapk cascadeGO:0051403930.013
response to decreased oxygen levelsGO:0036293960.013
defense response to other organismGO:00985421290.013
regulation of protein secretionGO:0050708860.013
potassium ion transmembrane transportGO:0071805600.013
engulfment of apoptotic cellGO:004365220.013
positive regulation of cytoplasmic transportGO:1903651820.013
organic hydroxy compound biosynthetic processGO:1901617710.013
potassium ion importGO:001010790.013
protein import into nucleusGO:00066061040.013
purine nucleotide biosynthetic processGO:0006164840.013
isoprenoid metabolic processGO:0006720390.013
anterior posterior axis specificationGO:000994820.013
myoblast fusionGO:000752010.013
compound eye developmentGO:004874910.013
organic hydroxy compound transportGO:0015850630.013
anterior posterior axis specification embryoGO:000859520.013
neural tube formationGO:000184130.013
regulation of multi organism processGO:00439001570.013
regulation of protein serine threonine kinase activityGO:00719001790.013
protein importGO:00170381300.013
anion transmembrane transportGO:0098656760.013
isoquinoline alkaloid metabolic processGO:003307610.013
retinoic acid biosynthetic processGO:000213820.013
cell divisionGO:00513011680.013
naphthalene containing compound metabolic processGO:009042010.013
response to extracellular stimulusGO:0009991850.013
regulation of transporter activityGO:0032409820.012
alpha amino acid metabolic processGO:1901605720.012
actin filament based movementGO:0030048170.012
response to nutrient levelsGO:0031667810.012
stress activated protein kinase signaling cascadeGO:0031098940.012
heart formationGO:006091420.012
embryonic epithelial tube formationGO:000183840.012
leukocyte activationGO:00453211640.012
positive regulation of gtpase activityGO:00435471660.012
regulation of bindingGO:00510981110.012

KLKB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.078
inherited metabolic disorderDOID:6552420.078
nervous system diseaseDOID:8634310.033
sensory system diseaseDOID:00501552030.033
immune system diseaseDOID:29141550.031
musculoskeletal system diseaseDOID:172230.030
central nervous system diseaseDOID:3311860.026
hematopoietic system diseaseDOID:741000.024
eye diseaseDOID:56141490.021
retinal diseaseDOID:56791180.021
eye and adnexa diseaseDOID:14921500.021
disease of cellular proliferationDOID:145661740.019
cancerDOID:1621670.018
organ system cancerDOID:00506861640.018
neurodegenerative diseaseDOID:12891020.017
myopathyDOID:4231040.017
muscular diseaseDOID:00800001140.017
muscle tissue diseaseDOID:661130.017
cardiovascular system diseaseDOID:12871060.016
connective tissue diseaseDOID:651090.015
amino acid metabolic disorderDOID:9252500.015
acquired metabolic diseaseDOID:0060158580.014
kidney diseaseDOID:557360.013
urinary system diseaseDOID:18400.013