Homo sapiens

18 known processes

SLK

STE20-like kinase

(Aliases: MGC133067,STK2,KIAA0204,LOSK,bA16H23.1,se20-9)

SLK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune responseGO:00069553070.284
cellular response to endogenous stimulusGO:00714953360.221
amine metabolic processGO:0009308440.207
post embryonic developmentGO:000979120.205
Worm
regulation of cellular amino acid metabolic processGO:000652160.193
cellular amino acid metabolic processGO:00065201160.185
small gtpase mediated signal transductionGO:0007264780.182
endomembrane system organizationGO:00102561960.172
ras protein signal transductionGO:0007265730.154
regulation of protein localizationGO:00328802960.136
purine ribonucleoside triphosphate metabolic processGO:00092054110.126
vesicle mediated transportGO:00161923710.125
cellular amine metabolic processGO:0044106410.123
positive regulation of phosphorylationGO:00423273940.123
Rat Fly
neural tube formationGO:000184130.122
regulation of nucleoside metabolic processGO:00091182090.115
purine ribonucleotide catabolic processGO:00091544040.115
purine nucleoside triphosphate metabolic processGO:00091444120.112
negative regulation of cell deathGO:00605483450.106
regulation of kinase activityGO:00435493140.105
behavioral response to ethanolGO:004814920.097
positive regulation of protein phosphorylationGO:00019343130.097
Rat Fly
cellular component morphogenesisGO:00329893140.096
Fly
mapk cascadeGO:00001652880.095
regulation of cellular amine metabolic processGO:0033238110.095
response to cytokineGO:00340972320.095
Rat
negative regulation of catalytic activityGO:00430863350.091
regulation of cellular response to stressGO:00801352440.089
endosomal transportGO:00161971290.088
protein autophosphorylationGO:00467771230.088
regulation of nucleotide catabolic processGO:00308112050.088
enzyme linked receptor protein signaling pathwayGO:00071673030.086
positive regulation of cellular amine metabolic processGO:003324070.084
regulation of cell cycleGO:00517263930.083
Fly
rab protein signal transductionGO:003248240.083
positive regulation of cellular component organizationGO:00511303760.082
Rat
positive regulation of gtp catabolic processGO:00331261660.081
negative regulation of apoptotic processGO:00430663160.081
regulation of cellular ketone metabolic processGO:0010565500.080
guanosine containing compound catabolic processGO:19010692390.080
regulation of locomotionGO:00400123290.080
Human
cytoplasmic transportGO:00164823790.079
female gamete generationGO:000729220.077
positive regulation of ras gtpase activityGO:00323201170.077
tissue morphogenesisGO:0048729960.077
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.077
morphogenesis of embryonic epitheliumGO:001633140.077
purine nucleoside triphosphate catabolic processGO:00091463920.075
signal transduction by phosphorylationGO:00230142970.074
regulation of protein kinase activityGO:00458592890.071
protein localization to plasma membraneGO:0072659930.071
rho protein signal transductionGO:0007266260.070
purine containing compound catabolic processGO:00725234110.070
memoryGO:000761330.067
organophosphate catabolic processGO:00464344300.066
regulation of growth rateGO:004000910.063
tube morphogenesisGO:0035239950.063
positive regulation of transferase activityGO:00513472270.062
cellular response to oxygen containing compoundGO:19017012760.062
negative regulation of cellular amine metabolic processGO:003323930.062
positive regulation of nucleoside metabolic processGO:00459791860.061
regulation of cellular component biogenesisGO:00440872810.061
purine nucleotide catabolic processGO:00061954050.061
regulation of mapk cascadeGO:00434082620.061
growthGO:00400072020.060
biological adhesionGO:00226103310.060
actin filament based processGO:00300292240.060
Fly
purine ribonucleoside triphosphate catabolic processGO:00092073910.059
regulation of growthGO:00400081650.059
nervous system developmentGO:00073992930.057
embryonic epithelial tube formationGO:000183840.057
nucleoside triphosphate metabolic processGO:00091414220.056
purine ribonucleoside catabolic processGO:00461303980.056
organelle assemblyGO:00709251760.055
response to growth factorGO:00708482050.055
regulation of purine nucleotide metabolic processGO:19005422640.054
behaviorGO:00076101120.053
cell projection organizationGO:00300302520.053
system processGO:00030083490.053
primary neural tube formationGO:001402030.052
positive regulation of purine nucleotide metabolic processGO:19005442270.051
regulation of ras protein signal transductionGO:00465781550.051
glycosyl compound catabolic processGO:19016584130.050
regulation of small gtpase mediated signal transductionGO:00510561560.050
golgi organizationGO:0007030380.050
microtubule based processGO:00070172100.050
Fly
negative regulation of intracellular signal transductionGO:19025321830.050
apoptotic signaling pathwayGO:00971902680.050
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.049
embryonic morphogenesisGO:0048598850.049
defense responseGO:00069523150.048
response to oxygen containing compoundGO:19017003690.048
positive regulation of gtpase activityGO:00435471660.047
regulation of gtpase activityGO:00430871800.047
regulation of vesicle mediated transportGO:00606271300.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
nucleotide catabolic processGO:00091664080.045
positive regulation of kinase activityGO:00336742040.044
oogenesisGO:004847720.044
regulation of transferase activityGO:00513383550.044
neuromuscular junction developmentGO:000752830.044
morphogenesis of an epitheliumGO:0002009600.043
purine nucleoside catabolic processGO:00061523980.043
response to radiationGO:00093141510.043
peptidyl serine phosphorylationGO:00181051010.043
positive regulation of purine nucleotide catabolic processGO:00331231850.042
purine ribonucleoside metabolic processGO:00461284370.042
cellular ketone metabolic processGO:0042180800.042
innate immune responseGO:00450871780.042
peptidyl tyrosine phosphorylationGO:00181081700.042
positive regulation of immune system processGO:00026842830.042
positive regulation of developmental processGO:00510943140.041
single organism cellular localizationGO:19025803320.041
Fly
maintenance of location in cellGO:0051651620.041
regulation of gtp catabolic processGO:00331241800.041
regulation of ras gtpase activityGO:00323181280.041
positive regulation of cellular catabolic processGO:00313312840.041
negative regulation of phosphate metabolic processGO:00459362670.040
intracellular protein transportGO:00068862700.039
mitotic cell cycleGO:00002783260.039
Fly
negative regulation of cellular component organizationGO:00511292350.039
positive regulation of protein kinase activityGO:00458601900.038
neural tube closureGO:000184330.038
regulation of protein processingGO:00706131500.038
determination of adult lifespanGO:000834020.038
tube closureGO:006060630.038
cell morphogenesisGO:00009022960.037
Fly
cellular protein catabolic processGO:00442572610.037
Fly
gtp catabolic processGO:00061842370.037
nuclear transportGO:00511691790.037
actin cytoskeleton organizationGO:00300362070.037
Fly
neuron differentiationGO:00301821380.036
regulation of nucleotide metabolic processGO:00061402690.036
neurological system processGO:00508771630.036
membrane organizationGO:00610242920.036
response to lipidGO:00339932060.036
positive regulation of catabolic processGO:00098963100.036
positive regulation of hydrolase activityGO:00513453310.036
regulation of cell cycle processGO:00105642660.036
Fly
response to abiotic stimulusGO:00096283360.036
regulation of apoptotic signaling pathwayGO:20012331750.036
negative regulation of phosphorus metabolic processGO:00105632670.036
ribonucleoside triphosphate catabolic processGO:00092033910.035
proteolysis involved in cellular protein catabolic processGO:00516032440.035
Fly
head developmentGO:00603221080.035
multicellular organismal agingGO:001025930.035
negative regulation of protein metabolic processGO:00512483910.035
negative regulation of peptidase activityGO:0010466910.035
epithelium developmentGO:00604292270.034
nucleoside phosphate catabolic processGO:19012924120.034
positive regulation of programmed cell deathGO:00430682490.034
Rat
mitotic cell cycle processGO:19030472860.034
Fly
organ morphogenesisGO:00098871470.034
cellular response to growth factor stimulusGO:00713631970.033
response to organonitrogen compoundGO:00102431560.033
negative regulation of cellular protein metabolic processGO:00322693530.033
dna repairGO:00062811980.033
anatomical structure formation involved in morphogenesisGO:00486462840.032
protein maturationGO:00516042330.032
immune system developmentGO:00025201950.032
reproductive processGO:00224141060.032
regulation of response to external stimulusGO:00321012220.032
positive regulation of protein serine threonine kinase activityGO:00719021190.031
oocyte developmentGO:004859910.031
protein localization to membraneGO:00726571600.031
regulation of establishment of protein localizationGO:00702012420.031
gtp metabolic processGO:00460392390.031
regulation of protein complex assemblyGO:00432541470.031
negative regulation of cellular amino acid metabolic processGO:004576320.031
cellular response to organonitrogen compoundGO:00714171240.030
negative regulation of hydrolase activityGO:00513461820.030
cellular response to abiotic stimulusGO:00712141170.030
plasma membrane organizationGO:00070091150.030
regulation of anatomical structure sizeGO:00900661010.030
response to uvGO:0009411730.030
regulation of cell differentiationGO:00455953930.030
peptidyl tyrosine modificationGO:00182121700.029
somitogenesisGO:000175620.029
nucleoside catabolic processGO:00091644080.029
maintenance of cell polarityGO:003001120.029
negative regulation of protein modification processGO:00314002000.028
chemical homeostasisGO:00488783060.028
cellular macromolecular complex assemblyGO:00346223240.028
neurogenesisGO:00220081690.028
endocytosisGO:00068971590.028
cell part morphogenesisGO:00329901370.028
wnt signaling pathwayGO:00160551560.028
regulation of rab protein signal transductionGO:0032483390.028
protein localization to organelleGO:00333652800.027
response to woundingGO:00096111680.027
positive regulation of mapk cascadeGO:00434101900.027
regulation of rab gtpase activityGO:0032313390.027
protein processingGO:00164852260.027
erbb signaling pathwayGO:0038127440.027
dephosphorylationGO:00163112090.027
cell cycle checkpointGO:00000751170.026
regulation of cellular component sizeGO:0032535820.026
cellular response to insulin stimulusGO:0032869410.026
intracellular mrna localizationGO:000829810.026
regulation of multi organism processGO:00439001570.026
regulation of response to dna damage stimulusGO:2001020940.026
guanosine containing compound metabolic processGO:19010682440.026
modification dependent macromolecule catabolic processGO:00436322120.025
Fly
regulation of immune responseGO:00507762010.025
protein localization to nucleusGO:00345041360.025
positive regulation of transportGO:00510503360.025
regulation of cell projection organizationGO:00313441070.025
positive regulation of rab gtpase activityGO:0032851390.025
regulation of tor signalingGO:0032006300.025
tube developmentGO:00352951250.025
regulation of defense responseGO:00313471540.025
regulation of protein maturationGO:19033171500.024
brain developmentGO:0007420970.024
regulation of cytoplasmic transportGO:19036491490.024
nucleocytoplasmic transportGO:00069131760.024
response to peptide hormoneGO:0043434610.024
morphogenesis of a polarized epitheliumGO:000173830.024
regulation of cytoskeleton organizationGO:00514931770.023
negative regulation of apoptotic signaling pathwayGO:2001234970.023
segmentationGO:003528240.023
negative regulation of proteolysisGO:00458611320.023
embryo developmentGO:00097901230.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
positive regulation of immune responseGO:00507781590.023
long term memoryGO:000761620.023
maintenance of protein location in cellGO:0032507560.023
cell morphogenesis involved in differentiationGO:00009041440.022
positive regulation of cell cycleGO:00457871400.022
cellular response to nitrogen compoundGO:19016991440.022
regulation of cell motilityGO:20001452990.022
Human
positive regulation of stress activated mapk cascadeGO:0032874600.022
protein catabolic processGO:00301633250.021
Fly
immune effector processGO:00022521590.021
positive regulation of nucleotide metabolic processGO:00459812300.021
regulation of dna metabolic processGO:00510521530.021
positive regulation of organelle organizationGO:00106381950.021
Rat
maintenance of locationGO:00512351120.021
extrinsic apoptotic signaling pathwayGO:00971911190.021
regulation of stress activated protein kinase signaling cascadeGO:0070302850.021
peptidyl serine modificationGO:00182091060.021
hindbrain developmentGO:003090230.021
response to external biotic stimulusGO:00432072610.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.020
negative regulation of phosphorylationGO:00423261740.020
negative regulation of protein processingGO:00109551420.020
positive regulation of cell migrationGO:00303351720.020
regulation of intracellular transportGO:00323861950.020
small molecule biosynthetic processGO:00442831570.020
regulation of proteolysisGO:00301622930.020
proteasomal protein catabolic processGO:00104981760.020
Fly
nucleoside triphosphate catabolic processGO:00091433940.020
cellular response to cytokine stimulusGO:00713451810.020
Rat
cell activationGO:00017752130.020
regulation of wnt signaling pathwayGO:00301111230.019
single organism nuclear importGO:19025931040.019
lipid metabolic processGO:00066293810.019
ribonucleotide catabolic processGO:00092614050.019
negative regulation of protein maturationGO:19033181420.019
regulation of nucleocytoplasmic transportGO:0046822980.019
cell adhesionGO:00071553250.019
protein ubiquitinationGO:00165673140.019
negative regulation of cell proliferationGO:00082852280.019
positive regulation of jnk cascadeGO:0046330520.019
organelle fissionGO:00482851490.019
Fly
regulation of peptidyl tyrosine phosphorylationGO:00507301080.018
regulation of stress activated mapk cascadeGO:0032872840.018
locomotory behaviorGO:000762610.018
cation homeostasisGO:00550801890.018
neuron developmentGO:00486661130.018
response to other organismGO:00517072610.018
single organism membrane organizationGO:00448022680.018
microtubule cytoskeleton organizationGO:00002261760.018
Fly
cellular response to dna damage stimulusGO:00069743790.018
axis elongationGO:000340140.018
cell type specific apoptotic processGO:00972851250.018
response to tumor necrosis factorGO:0034612760.018
Rat
stress activated mapk cascadeGO:0051403930.017
regulation of purine nucleotide catabolic processGO:00331212050.017
cytokine mediated signaling pathwayGO:00192211090.017
positive regulation of wnt signaling pathwayGO:0030177540.017
response to nitrogen compoundGO:19016981840.017
peripheral nervous system developmentGO:000742220.017
single organismal cell cell adhesionGO:00163371480.017
regulation of erk1 and erk2 cascadeGO:0070372990.017
jnk cascadeGO:0007254800.017
lipid localizationGO:00108761060.017
response to light stimulusGO:0009416870.017
negative regulation of multicellular organismal processGO:00512413170.017
nitrogen compound transportGO:00717051910.017
cell developmentGO:00484683280.017
cation transportGO:00068123310.017
regulation of homeostatic processGO:00328441210.017
heart developmentGO:0007507950.016
cellular response to transforming growth factor beta stimulusGO:0071560940.016
response to transforming growth factor betaGO:0071559940.016
digestive tract developmentGO:0048565750.016
organelle localizationGO:0051640840.016
Fly
secretionGO:00469032540.016
cellular response to hormone stimulusGO:00328701250.016
regulation of anatomical structure morphogenesisGO:00226032860.016
negative regulation of kinase activityGO:00336731060.016
negative regulation of endopeptidase activityGO:0010951840.016
cell projection morphogenesisGO:00488581290.016
maintenance of protein locationGO:0045185570.016
establishment of protein localization to plasma membraneGO:0090002680.015
response to biotic stimulusGO:00096072760.015
cell cell signalingGO:00072671550.015
golgi vesicle transportGO:0048193800.015
digestive system developmentGO:0055123750.015
cellular macromolecule catabolic processGO:00442653800.015
Fly
regulation of neurogenesisGO:0050767820.015
response to hormoneGO:00097251750.015
regulation of protein catabolic processGO:00421761550.015
regulation of protein localization to nucleusGO:1900180850.015
hair cell differentiationGO:003531520.015
cell agingGO:0007569520.015
regulation of cellular component movementGO:00512703340.015
Human
protein targetingGO:00066051870.015
protein import into nucleusGO:00066061040.015
ncrna processingGO:0034470830.015
regulation of secretionGO:00510461940.015
positive regulation of cell developmentGO:0010720920.015
regulation of cell developmentGO:00602841610.015
reactive nitrogen species metabolic processGO:200105730.015
neuroblast proliferationGO:000740540.015
neuron projection developmentGO:00311751060.014
ameboidal type cell migrationGO:00016671350.014
histone modificationGO:00165702510.014
Rat
regulation of protein stabilityGO:0031647870.014
ubiquitin dependent protein catabolic processGO:00065112060.014
Fly
oocyte differentiationGO:000999420.014
regulation of protein targetingGO:1903533910.014
regulation of canonical wnt signaling pathwayGO:0060828880.014
negative regulation of immune system processGO:00026831360.014
regulation of map kinase activityGO:00434051080.014
divalent inorganic cation homeostasisGO:00725071360.014
amide biosynthetic processGO:0043604150.014
response to peptideGO:1901652650.014
positive regulation of nucleotide catabolic processGO:00308131850.014
tor signalingGO:0031929390.014
negative regulation of organelle organizationGO:00106391260.013
positive regulation of cell deathGO:00109422630.013
Rat
regulation of cellular protein catabolic processGO:1903362960.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
Fly
anterior posterior axis specificationGO:000994820.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
negative regulation of transferase activityGO:00513481240.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
compound eye developmentGO:004874910.013
regulation of cell morphogenesisGO:00226041530.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
organelle fusionGO:0048284360.013
positive regulation of secretionGO:00510471160.013
cellular lipid metabolic processGO:00442553030.013
inner ear morphogenesisGO:004247240.013
regulation of cell divisionGO:00513021160.013
Fly
regulation of dna replicationGO:0006275680.013
spermatid developmentGO:000728640.013
metal ion transportGO:00300012720.013
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059110.013
cell growthGO:00160491600.013
regulation of response to woundingGO:19030341010.013
establishment of protein localization to membraneGO:00901501210.013
generation of neuronsGO:00486991520.013
cellular response to lipidGO:00713961270.012
negative regulation of programmed cell deathGO:00430693210.012
negative regulation of protein kinase activityGO:0006469980.012
receptor metabolic processGO:0043112810.012
regulation of endopeptidase activityGO:00525481700.012
fibroblast growth factor receptor signaling pathwayGO:0008543260.012
single organism reproductive processGO:0044702980.012
lipid homeostasisGO:0055088390.012
secretion by cellGO:00329402260.012
calcium ion homeostasisGO:00550741220.012
regulation of immune effector processGO:0002697910.012
nucleus localizationGO:005164710.012
cardiovascular system developmentGO:00723582620.012
protein modification by small protein removalGO:0070646920.012
meiotic chromosome segregationGO:004513240.012
myeloid cell differentiationGO:00300991170.012
protein deubiquitinationGO:0016579790.012
ion transmembrane transportGO:00342203380.012
response to alcoholGO:0097305640.012
metencephalon developmentGO:002203720.012
reproductionGO:0000003630.012
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.012
rna processingGO:00063962550.012
cell divisionGO:00513011680.012
Fly
positive regulation of apoptotic processGO:00430652460.012
Rat
response to inorganic substanceGO:00100351270.012
protein oligomerizationGO:00512591730.012
multi organism cellular processGO:00447641560.012
wound healingGO:00420601150.012
positive regulation of cell proliferationGO:00082843010.012
cell cell junction organizationGO:0045216690.012
cell fate determinationGO:000170930.012
viral life cycleGO:00190581320.012
positive regulation of intracellular transportGO:00323881040.011
regulation of actin cytoskeleton organizationGO:00329561160.011
regulation of cell adhesionGO:00301551660.011
chemotaxisGO:00069351570.011
regulation of jnk cascadeGO:0046328730.011
inorganic cation transmembrane transportGO:00986621940.011
dna replicationGO:00062601160.011
response to oxidative stressGO:00069791210.011
circadian behaviorGO:004851220.011
positive regulation of rho gtpase activityGO:0032321560.011
organonitrogen compound biosynthetic processGO:19015662000.011
regulation of receptor mediated endocytosisGO:0048259320.011
cell junction organizationGO:0034330790.011
actin filament organizationGO:00070151280.011
positive regulation of response to external stimulusGO:0032103880.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
response to organic cyclic compoundGO:00140702040.011
regulation of cell growthGO:00015581350.011
spindle organizationGO:0007051530.011
Fly
positive regulation of cytoskeleton organizationGO:0051495830.011
cellular protein complex assemblyGO:00436231880.011
mitochondrion organizationGO:00070051560.011
cellular homeostasisGO:00197251960.011
epidermal growth factor receptor signaling pathwayGO:0007173390.011
positive regulation of cell motilityGO:20001471770.011
response to bacteriumGO:00096171440.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
sensory perceptionGO:00076001030.011
vesicle organizationGO:0016050620.011
glycerophospholipid metabolic processGO:0006650840.011
dna integrity checkpointGO:0031570710.010
regulation of cell activationGO:00508651250.010
establishment of nucleus localizationGO:004002310.010
positive regulation of protein transportGO:00512221350.010
regulation of endocytosisGO:0030100720.010
mitotic nuclear divisionGO:00070671190.010
Fly
single organism behaviorGO:0044708280.010
regulation of membrane potentialGO:0042391950.010
positive regulation of growthGO:0045927580.010
dna recombinationGO:0006310770.010
positive regulation of humoral immune responseGO:000292230.010
negative regulation of growthGO:0045926970.010

SLK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.039
disease of cellular proliferationDOID:145661740.039
organ system cancerDOID:00506861640.039
endocrine gland cancerDOID:170260.038
eye diseaseDOID:56141490.010
sensory system diseaseDOID:00501552030.010
eye and adnexa diseaseDOID:14921500.010
nervous system diseaseDOID:8634310.010