Homo sapiens

71 known processes

MCC

mutated in colorectal cancers

(Aliases: MCC1,DKFZp762O1615,FLJ38893,FLJ46755)

MCC biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment or maintenance of bipolar cell polarityGO:006124520.572
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.535
somatic stem cell maintenanceGO:003501940.488
anatomical structure formation involved in morphogenesisGO:00486462840.445
nervous system developmentGO:00073992930.288
cellular component morphogenesisGO:00329893140.286
purine nucleoside catabolic processGO:00061523980.249
morphogenesis of embryonic epitheliumGO:001633140.225
hindbrain developmentGO:003090230.225
forebrain regionalizationGO:002187130.222
cellular amino acid metabolic processGO:00065201160.220
wnt signaling pathwayGO:00160551560.207
cell developmentGO:00484683280.193
purine ribonucleotide catabolic processGO:00091544040.192
purine ribonucleoside metabolic processGO:00461284370.190
regulation of cell cycleGO:00517263930.187
establishment or maintenance of apical basal cell polarityGO:003508820.186
locomotory behaviorGO:000762610.186
heart formationGO:006091420.177
response to cocaineGO:004222010.174
cardiovascular system developmentGO:00723582620.174
establishment of tissue polarityGO:000716430.174
photoreceptor cell differentiationGO:004653020.169
single organism cellular localizationGO:19025803320.168
positive regulation of phosphorylationGO:00423273940.151
rhythmic behaviorGO:000762220.146
purine nucleoside triphosphate catabolic processGO:00091463920.141
organ morphogenesisGO:00098871470.140
organ formationGO:004864530.138
guanosine containing compound metabolic processGO:19010682440.137
endocrine processGO:0050886250.135
small gtpase mediated signal transductionGO:0007264780.135
negative regulation of cell fate specificationGO:000999630.134
cell morphogenesisGO:00009022960.133
circulatory system developmentGO:00723592620.133
nerve developmentGO:002167540.132
neuron differentiationGO:00301821380.130
positive regulation of catabolic processGO:00098963100.130
generation of neuronsGO:00486991520.129
female gamete generationGO:000729220.129
post embryonic developmentGO:000979120.128
cellular amine metabolic processGO:0044106410.126
ribonucleotide catabolic processGO:00092614050.123
positive regulation of wnt signaling pathwayGO:0030177540.122
motor neuron axon guidanceGO:000804520.120
epidermis morphogenesisGO:004873030.119
circadian behaviorGO:004851220.119
eye photoreceptor cell differentiationGO:000175420.118
regulation of mitotic cell cycleGO:00073461890.118
purine nucleoside triphosphate metabolic processGO:00091444120.116
sensory organ morphogenesisGO:0090596210.114
system processGO:00030083490.114
neuron fate commitmentGO:004866320.113
stress activated protein kinase signaling cascadeGO:0031098940.111
regulation of mapk cascadeGO:00434082620.109
inner ear morphogenesisGO:004247240.109
regulation of cellular amino acid metabolic processGO:000652160.109
cell projection organizationGO:00300302520.107
establishment of apical basal cell polarityGO:003508910.103
behaviorGO:00076101120.103
purine ribonucleoside catabolic processGO:00461303980.102
actin filament based processGO:00300292240.102
nucleoside phosphate catabolic processGO:19012924120.100
ribonucleoside catabolic processGO:00424544060.099
salivary gland morphogenesisGO:000743540.098
cellular ketone metabolic processGO:0042180800.098
negative regulation of cell fate commitmentGO:001045430.097
morphogenesis of a polarized epitheliumGO:000173830.096
purine ribonucleoside triphosphate catabolic processGO:00092073910.095
heart morphogenesisGO:0003007480.095
nucleotide catabolic processGO:00091664080.093
purine containing compound catabolic processGO:00725234110.091
organelle assemblyGO:00709251760.090
ribonucleoside triphosphate metabolic processGO:00091994120.090
nucleoside catabolic processGO:00091644080.089
cofactor metabolic processGO:0051186870.088
cardiac chamber formationGO:000320720.088
regulation of purine nucleotide catabolic processGO:00331212050.087
regulation of purine nucleotide metabolic processGO:19005422640.087
regulation of cell migrationGO:00303342890.086
regulation of cell motilityGO:20001452990.085
amine metabolic processGO:0009308440.085
nucleoside triphosphate metabolic processGO:00091414220.084
epithelium developmentGO:00604292270.084
establishment or maintenance of monopolar cell polarityGO:006133910.083
cytoplasmic transportGO:00164823790.083
organophosphate catabolic processGO:00464344300.082
nucleoside triphosphate catabolic processGO:00091433940.081
canonical wnt signaling pathway involved in heart developmentGO:006131630.080
signal transduction by phosphorylationGO:00230142970.079
rho protein signal transductionGO:0007266260.079
pancreatic a cell differentiationGO:000331010.079
neural tube formationGO:000184130.079
mitotic cell cycleGO:00002783260.079
forebrain generation of neuronsGO:002187230.078
segmentationGO:003528240.078
jnk cascadeGO:0007254800.078
regulation of cardioblast differentiationGO:005189040.078
regulation of cellular ketone metabolic processGO:0010565500.077
mitotic cell cycle processGO:19030472860.077
positive regulation of cellular catabolic processGO:00313312840.076
mapk cascadeGO:00001652880.075
oogenesisGO:004847720.074
purine ribonucleoside triphosphate metabolic processGO:00092054110.074
endodermal cell fate specificationGO:000171440.072
tube developmentGO:00352951250.072
guanosine containing compound catabolic processGO:19010692390.072
positive regulation of kinase activityGO:00336742040.071
cranial nerve developmentGO:002154540.071
purine nucleotide catabolic processGO:00061954050.070
regulation of cell cycle processGO:00105642660.070
canonical wnt signaling pathwayGO:00600701160.069
regulation of cellular component movementGO:00512703340.069
positive regulation of protein phosphorylationGO:00019343130.069
cell junction organizationGO:0034330790.069
ras protein signal transductionGO:0007265730.068
vesicle mediated transportGO:00161923710.067
regulation of cardiac cell fate specificationGO:200004310.066
heart field specificationGO:000312820.066
positive regulation of purine nucleotide metabolic processGO:19005442270.066
positive regulation of gtpase activityGO:00435471660.066
regulation of ras protein signal transductionGO:00465781550.065
morphogenesis of an epitheliumGO:0002009600.065
regulation of stress activated protein kinase signaling cascadeGO:0070302850.065
regulation of organ formationGO:000315640.065
ribonucleoside triphosphate catabolic processGO:00092033910.064
microtubule cytoskeleton organizationGO:00002261760.064
gtp catabolic processGO:00061842370.064
response to abiotic stimulusGO:00096283360.064
positive regulation of transferase activityGO:00513472270.064
positive regulation of map kinase activityGO:0043406800.064
cell projection assemblyGO:00300311260.063
gtp metabolic processGO:00460392390.063
regulation of anatomical structure morphogenesisGO:00226032860.062
regulation of kinase activityGO:00435493140.062
epithelial cell differentiationGO:00308551410.061
regulation of heart inductionGO:009038120.061
regulation of stress activated mapk cascadeGO:0032872840.060
cellular protein catabolic processGO:00442572610.060
regulation of nucleotide metabolic processGO:00061402690.060
neural crest cell developmentGO:001403230.059
primary neural tube formationGO:001402030.059
regulation of protein kinase activityGO:00458592890.059
postsynaptic membrane organizationGO:000194120.059
positive regulation of protein serine threonine kinase activityGO:00719021190.058
cell adhesionGO:00071553250.058
neurological system processGO:00508771630.057
pituitary gland developmentGO:002198320.057
negative regulation of phosphate metabolic processGO:00459362670.057
positive regulation of cellular amino acid metabolic processGO:004576430.057
protein localization to organelleGO:00333652800.056
cilium assemblyGO:0042384630.056
positive regulation of jnk cascadeGO:0046330520.056
positive regulation of canonical wnt signaling pathwayGO:0090263330.056
negative regulation of multicellular organismal processGO:00512413170.055
wound healingGO:00420601150.055
positive regulation of ras gtpase activityGO:00323201170.055
regulation of protein serine threonine kinase activityGO:00719001790.055
regulation of gtpase activityGO:00430871800.055
neurotransmitter secretionGO:000726940.054
negative regulation of phosphorus metabolic processGO:00105632670.054
positive regulation of protein kinase activityGO:00458601900.054
positive regulation of cellular amine metabolic processGO:003324070.053
embryo developmentGO:00097901230.053
cellular macromolecule catabolic processGO:00442653800.053
regulation of cellular component biogenesisGO:00440872810.052
negative regulation of developmental processGO:00510932470.052
sensory organ developmentGO:0007423520.051
sensory perceptionGO:00076001030.051
regulation of jnk cascadeGO:0046328730.051
actin cytoskeleton organizationGO:00300362070.051
glycosyl compound catabolic processGO:19016584130.051
neural tube closureGO:000184330.051
regulation of nucleoside metabolic processGO:00091182090.050
regulation of locomotionGO:00400123290.050
positive regulation of nucleotide catabolic processGO:00308131850.050
negative regulation of cell deathGO:00605483450.050
cell projection morphogenesisGO:00488581290.050
digestive tract developmentGO:0048565750.050
cell fate determinationGO:000170930.050
positive regulation of stress activated mapk cascadeGO:0032874600.050
negative regulation of phosphorylationGO:00423261740.050
neuron developmentGO:00486661130.050
neuroblast proliferationGO:000740540.049
enzyme linked receptor protein signaling pathwayGO:00071673030.049
ameboidal type cell migrationGO:00016671350.049
neurogenesisGO:00220081690.049
regulation of circadian sleep wake cycleGO:004274920.048
establishment of monopolar cell polarityGO:006116210.048
taxisGO:00423301570.048
central nervous system developmentGO:00074171230.048
intracellular protein transportGO:00068862700.048
response to organic cyclic compoundGO:00140702040.048
axon cargo transportGO:000808820.048
tube morphogenesisGO:0035239950.047
positive regulation of mapk cascadeGO:00434101900.047
negative regulation of cardioblast differentiationGO:005189220.047
tube closureGO:006060630.047
embryonic morphogenesisGO:0048598850.046
regulation of canonical wnt signaling pathwayGO:0060828880.046
regulation of gtp catabolic processGO:00331241800.046
microtubule based processGO:00070172100.046
positive regulation of developmental processGO:00510943140.046
anterior posterior axis specificationGO:000994820.045
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.045
response to nitrogen compoundGO:19016981840.045
brain developmentGO:0007420970.045
coenzyme metabolic processGO:0006732650.044
head developmentGO:00603221080.044
establishment of planar polarityGO:000173630.044
heart inductionGO:000312940.044
negative regulation of cell proliferationGO:00082852280.044
digestive system developmentGO:0055123750.044
positive regulation of nucleoside metabolic processGO:00459791860.044
positive regulation of cell differentiationGO:00455972110.044
regulation of nucleotide catabolic processGO:00308112050.043
response to oxygen containing compoundGO:19017003690.043
cell divisionGO:00513011680.043
heart developmentGO:0007507950.042
regulation of proteolysisGO:00301622930.042
regulation of protein localizationGO:00328802960.042
biological adhesionGO:00226103310.042
regulation of cytoskeleton organizationGO:00514931770.042
positive regulation of nucleotide metabolic processGO:00459812300.041
neuron projection developmentGO:00311751060.041
tissue morphogenesisGO:0048729960.041
startle responseGO:000196430.041
circadian sleep wake cycleGO:004274520.041
chemotaxisGO:00069351570.041
regulation of cell projection organizationGO:00313441070.041
hair cell differentiationGO:003531520.041
axis elongationGO:000340140.041
positive regulation of gtp catabolic processGO:00331261660.041
regulation of circadian sleep wake cycle sleepGO:004518720.040
chromatin organizationGO:00063253510.040
regulation of ras gtpase activityGO:00323181280.040
regulation of wnt signaling pathwayGO:00301111230.040
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.040
meiotic chromosome segregationGO:004513240.040
response to woundingGO:00096111680.040
regulation of cell differentiationGO:00455953930.040
single organism membrane organizationGO:00448022680.040
cell morphogenesis involved in differentiationGO:00009041440.040
positive regulation of cell migrationGO:00303351720.039
multicellular organismal agingGO:001025930.039
g protein coupled receptor signaling pathwayGO:00071862070.039
cell part morphogenesisGO:00329901370.038
regulation of embryonic developmentGO:0045995200.038
peptidyl tyrosine phosphorylationGO:00181081700.038
positive regulation of proteasomal protein catabolic processGO:1901800350.038
embryonic epithelial tube formationGO:000183840.038
positive regulation of locomotionGO:00400171860.037
metencephalon developmentGO:002203720.037
negative regulation of protein metabolic processGO:00512483910.037
adult locomotory behaviorGO:000834410.037
metanephric nephron tubule morphogenesisGO:007228210.037
glial cell migrationGO:000834740.037
actin mediated cell contractionGO:0070252120.037
determination of adult lifespanGO:000834020.037
meiosis iGO:000712740.036
protein autophosphorylationGO:00467771230.036
regulation of cellular response to stressGO:00801352440.036
convergent extensionGO:006002610.036
cellular response to dna damage stimulusGO:00069743790.036
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.036
positive regulation of purine nucleotide catabolic processGO:00331231850.036
chromosome segregationGO:00070591140.036
circadian sleep wake cycle sleepGO:005080220.035
cell junction assemblyGO:0034329670.035
cochlea developmentGO:009010210.035
positive regulation of hydrolase activityGO:00513453310.035
cellular component assembly involved in morphogenesisGO:0010927730.035
regulation of sequence specific dna binding transcription factor activityGO:00510902110.035
modification dependent protein catabolic processGO:00199412090.035
spermatid developmentGO:000728640.034
regulation of bindingGO:00510981110.034
cardiac cell fate specificationGO:006091210.034
response to organonitrogen compoundGO:00102431560.034
negative regulation of protein modification processGO:00314002000.033
actin filament based movementGO:0030048170.033
stress activated mapk cascadeGO:0051403930.033
protein localization to membraneGO:00726571600.033
regulation of heart morphogenesisGO:200082640.033
regulation of transferase activityGO:00513383550.032
secretionGO:00469032540.032
regulation of cellular amine metabolic processGO:0033238110.032
regulation of cell morphogenesisGO:00226041530.032
cell growthGO:00160491600.032
positive regulation of transportGO:00510503360.032
mechanosensory behaviorGO:000763840.032
cilium organizationGO:0044782680.032
regulation of cell divisionGO:00513021160.032
positive regulation of neural precursor cell proliferationGO:200017920.032
trna modificationGO:0006400100.032
neural tube patterningGO:002153220.031
cell cell junction organizationGO:0045216690.031
positive regulation of cellular component movementGO:00512721810.031
negative regulation of cellular protein metabolic processGO:00322693530.031
embryonic skeletal joint developmentGO:007249820.031
thymus developmentGO:004853830.031
regulation of map kinase activityGO:00434051080.031
ventricular septum morphogenesisGO:006041230.030
oocyte developmentGO:004859910.030
negative regulation of intracellular signal transductionGO:19025321830.030
secretion by cellGO:00329402260.030
retinal ganglion cell axon guidanceGO:003129020.030
establishment of organelle localizationGO:0051656590.030
maintenance of locationGO:00512351120.030
organ inductionGO:000175940.030
positive regulation of immune system processGO:00026842830.030
regulation of secretionGO:00510461940.030
membrane organizationGO:00610242920.029
activation of protein kinase activityGO:0032147900.029
blood vessel morphogenesisGO:00485141620.029
regulation of mitosisGO:0007088630.029
positive regulation of cell motilityGO:20001471770.029
blood vessel developmentGO:00015681720.029
modification dependent macromolecule catabolic processGO:00436322120.029
maintenance of protein locationGO:0045185570.029
sulfur compound metabolic processGO:00067901010.029
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.028
cell fate commitment involved in pattern specificationGO:006058110.028
negative regulation of glial cell proliferationGO:006025320.028
cellular modified amino acid metabolic processGO:0006575640.028
protein catabolic processGO:00301633250.028
regulation of proteasomal protein catabolic processGO:0061136870.028
ncrna metabolic processGO:00346601080.028
sleepGO:003043120.028
neuromuscular junction developmentGO:000752830.028
mitotic nuclear divisionGO:00070671190.027
trna processingGO:0008033230.027
hippo signalingGO:0035329200.027
cardioblast cell fate commitmentGO:004268410.027
regulation of steroid hormone secretionGO:200083170.027
negative regulation of apoptotic processGO:00430663160.027
positive regulation of rho gtpase activityGO:0032321560.027
positive regulation of cellular component organizationGO:00511303760.027
protein acylationGO:00435431380.027
embryonic organ developmentGO:0048568360.026
negative regulation of catalytic activityGO:00430863350.026
regulation of response to external stimulusGO:00321012220.026
protein importGO:00170381300.026
regulation of cytokine productionGO:00018172320.026
nuclear divisionGO:00002801280.026
circadian sleep wake cycle processGO:002241020.026
establishment of protein localization to organelleGO:00725941720.026
positive regulation of jun kinase activityGO:0043507230.026
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.026
regulation of mitotic cell cycle phase transitionGO:19019901180.025
spermatid differentiationGO:004851540.025
cell cell signalingGO:00072671550.025
alpha amino acid metabolic processGO:1901605720.025
positive regulation of gliogenesisGO:001401540.025
peptidyl tyrosine modificationGO:00182121700.025
maintenance of protein location in cellGO:0032507560.025
vasculature developmentGO:00019441810.025
negative regulation of cell differentiationGO:00455961710.025
specification of organ identityGO:001009230.025
regulation of protein catabolic processGO:00421761550.025
lipid transportGO:0006869900.025
carbohydrate metabolic processGO:00059752070.025
epidermis developmentGO:0008544590.025
organelle localizationGO:0051640840.025
cilium morphogenesisGO:0060271750.024
internal protein amino acid acetylationGO:00064751010.024
neuroendocrine cell differentiationGO:006110120.024
regionalizationGO:0003002290.024
regulation of small gtpase mediated signal transductionGO:00510561560.024
epithelial tube morphogenesisGO:0060562380.024
cytokine productionGO:00018162470.024
signal releaseGO:0023061700.024
histone acetylationGO:0016573930.024
protein localization to nucleusGO:00345041360.024
regulation of growthGO:00400081650.023
positive regulation of proteolysisGO:00458621420.023
negative regulation of heart induction by canonical wnt signaling pathwayGO:000313610.023
epidermal cell differentiationGO:0009913450.023
negative regulation of protein phosphorylationGO:00019331400.023
anterior posterior axis specification embryoGO:000859520.023
single organism reproductive processGO:0044702980.023
regenerationGO:003109940.023
protein oligomerizationGO:00512591730.023
negative chemotaxisGO:0050919110.023
regulation of microtubule based processGO:0032886740.023
pattern specification processGO:0007389430.023
defense responseGO:00069523150.022
positive regulation of neuroblast proliferationGO:000205220.022
metal ion transportGO:00300012720.022
proteasomal protein catabolic processGO:00104981760.022
negative regulation of programmed cell deathGO:00430693210.022
regulation of dna metabolic processGO:00510521530.022
regulation of microtubule cytoskeleton organizationGO:0070507610.022
chordate embryonic developmentGO:0043009340.022
nuclear transportGO:00511691790.022
growthGO:00400072020.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.022
steroid hormone secretionGO:003592980.022
ubiquitin dependent protein catabolic processGO:00065112060.022
i kappab kinase nf kappab signalingGO:00072491660.022
single organism cell adhesionGO:00986021790.022
regulation of jun kinase activityGO:0043506270.022
negative regulation of cell cycleGO:00457861930.022
protein targetingGO:00066051870.021
cellular protein complex assemblyGO:00436231880.021
developmental process involved in reproductionGO:0003006660.021
regulation of peptidyl tyrosine phosphorylationGO:00507301080.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
negative regulation of cardioblast cell fate specificationGO:000999710.021
regulation of cell developmentGO:00602841610.021
regulation of neural precursor cell proliferationGO:200017740.021
angiogenesisGO:00015251470.021
maintenance of location in cellGO:0051651620.021
cardiac chamber morphogenesisGO:0003206260.021
actin filament organizationGO:00070151280.021
forebrain neuron differentiationGO:002187930.021
endocytosisGO:00068971590.021
nucleocytoplasmic transportGO:00069131760.021
mammary gland morphogenesisGO:006044320.021
notch signaling pathwayGO:0007219310.021
dna repairGO:00062811980.021
positive regulation of cell developmentGO:0010720920.021
regulation of vesicle mediated transportGO:00606271300.021
regulation of cell cycle phase transitionGO:19019871260.020
muscle structure developmentGO:0061061980.020
skin developmentGO:0043588760.020
dephosphorylationGO:00163112090.020
blastoderm segmentationGO:000735020.020
regulation of nuclear divisionGO:0051783650.020
ectodermal placode formationGO:006078810.020
anatomical structure homeostasisGO:00602491000.020
protein targeting to nucleusGO:00447441040.020
epithelial cell migrationGO:00106311190.020
negative regulation of gliogenesisGO:001401430.020
cell substrate adhesionGO:00315891320.020
regulation of glial cell differentiationGO:004568530.020
tripartite regional subdivisionGO:000735120.020
regulation of epithelial cell migrationGO:0010632930.020
protein homooligomerizationGO:00512601000.020
rna processingGO:00063962550.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
nitrogen compound transportGO:00717051910.020
endodermal cell fate commitmentGO:000171140.019
monovalent inorganic cation transportGO:00156721280.019
metanephric tubule developmentGO:007217030.019
ectodermal placode developmentGO:007169610.019
cation transportGO:00068123310.019
posttranscriptional regulation of gene expressionGO:00106082130.019
histone modificationGO:00165702510.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
mitotic cell cycle phase transitionGO:00447721620.019
nucleoside monophosphate metabolic processGO:00091231910.019
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434020.019
sensory perception of soundGO:0007605370.019
positive regulation of programmed cell deathGO:00430682490.019
formation of primary germ layerGO:0001704420.019
hemopoiesisGO:00300971800.018
embryonic digestive tract morphogenesisGO:004855720.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.018
cerebellum developmentGO:002154920.018
somitogenesisGO:000175620.018
monocarboxylic acid metabolic processGO:00327871850.018
regulation of astrocyte differentiationGO:004871030.018
negative regulation of cellular component organizationGO:00511292350.018
regulation of cell growthGO:00015581350.018
negative regulation of cell migrationGO:00303361020.018
transmembrane transportGO:00550853990.018
response to radiationGO:00093141510.018
cardioblast cell fate specificationGO:004268510.018
protein maturationGO:00516042330.018
lamellipodium organizationGO:0097581300.018
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.018
developmental programmed cell deathGO:001062330.018
positive regulation of rho protein signal transductionGO:003502540.018
organonitrogen compound biosynthetic processGO:19015662000.018
regulation of rho gtpase activityGO:0032319660.018
actin filament bundle organizationGO:0061572540.017
spindle organizationGO:0007051530.017
regulation of neuron differentiationGO:0045664700.017
reproductive processGO:00224141060.017
eye morphogenesisGO:0048592160.017
reproductive structure developmentGO:0048608550.017
chromatin modificationGO:00165682980.017
memoryGO:000761330.017

MCC disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.052
disease of cellular proliferationDOID:145661740.044
gastrointestinal system diseaseDOID:77360.029
mouth diseaseDOID:403140.029
tooth diseaseDOID:1091140.029
teeth hard tissue diseaseDOID:21480.029
inherited metabolic disorderDOID:6552420.028
cancerDOID:1621670.023
disease of mental healthDOID:150700.020
central nervous system diseaseDOID:3311860.017
nervous system diseaseDOID:8634310.017