Homo sapiens

111 known processes

RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6

(Aliases: KIA001LB,DKFZp667N084,DKFZp686I15116,PDZGEF2,RA-GEF-2,RAGEF2,PDZ-GEF2)

RAPGEF6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein dephosphorylationGO:0006470810.286
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.242
peptidyl tyrosine dephosphorylationGO:0035335360.234
dephosphorylationGO:00163112090.201
nucleoside catabolic processGO:00091644080.177
post embryonic developmentGO:000979120.144
Fly
guanosine containing compound catabolic processGO:19010692390.138
purine nucleotide catabolic processGO:00061954050.133
small gtpase mediated signal transductionGO:0007264780.132
Human
cellular amine metabolic processGO:0044106410.123
purine ribonucleotide catabolic processGO:00091544040.123
cellular amino acid metabolic processGO:00065201160.123
phosphatidylinositol mediated signalingGO:0048015550.111
regulation of cellular amine metabolic processGO:0033238110.110
ribonucleoside triphosphate catabolic processGO:00092033910.109
cellular ketone metabolic processGO:0042180800.108
gtp catabolic processGO:00061842370.106
ribonucleoside catabolic processGO:00424544060.104
nucleoside triphosphate metabolic processGO:00091414220.103
purine ribonucleoside metabolic processGO:00461284370.102
gtp metabolic processGO:00460392390.101
guanosine containing compound metabolic processGO:19010682440.100
regulation of purine nucleotide metabolic processGO:19005422640.099
cell junction assemblyGO:0034329670.094
Human Fly
regulation of cellular ketone metabolic processGO:0010565500.094
regulation of nucleoside metabolic processGO:00091182090.091
amine metabolic processGO:0009308440.091
lipid metabolic processGO:00066293810.091
organophosphate catabolic processGO:00464344300.089
purine nucleoside triphosphate catabolic processGO:00091463920.088
ribonucleotide catabolic processGO:00092614050.083
mitotic cell cycleGO:00002783260.082
positive regulation of nucleotide catabolic processGO:00308131850.075
regulation of cell cycleGO:00517263930.074
purine containing compound catabolic processGO:00725234110.069
ribonucleoside triphosphate metabolic processGO:00091994120.069
cell junction organizationGO:0034330790.069
Human Fly
protein autophosphorylationGO:00467771230.067
positive regulation of purine nucleotide metabolic processGO:19005442270.067
nucleoside phosphate catabolic processGO:19012924120.067
regulation of cell differentiationGO:00455953930.062
Human Fly
positive regulation of gtpase activityGO:00435471660.061
positive regulation of nucleoside metabolic processGO:00459791860.061
nucleotide catabolic processGO:00091664080.058
regulation of cellular amino acid metabolic processGO:000652160.056
purine ribonucleoside catabolic processGO:00461303980.054
positive regulation of ras gtpase activityGO:00323201170.054
Human Fly
ras protein signal transductionGO:0007265730.053
Human
rho protein signal transductionGO:0007266260.051
tight junction assemblyGO:0070830140.050
determination of adult lifespanGO:000834020.049
negative regulation of phosphate metabolic processGO:00459362670.049
cell developmentGO:00484683280.049
Human Fly
negative regulation of phosphorus metabolic processGO:00105632670.047
regulation of cell cycle processGO:00105642660.047
positive regulation of phosphorylationGO:00423273940.046
Human
cytokinesisGO:0000910960.045
purine nucleoside triphosphate metabolic processGO:00091444120.045
positive regulation of catabolic processGO:00098963100.044
female gamete generationGO:000729220.043
Fly
regulation of nucleotide metabolic processGO:00061402690.042
purine ribonucleoside triphosphate metabolic processGO:00092054110.041
oogenesisGO:004847720.040
Fly
positive regulation of gtp catabolic processGO:00331261660.039
multicellular organismal agingGO:001025930.039
positive regulation of cellular catabolic processGO:00313312840.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
negative regulation of catalytic activityGO:00430863350.037
cell morphogenesisGO:00009022960.037
Human Fly
purine nucleoside catabolic processGO:00061523980.036
negative regulation of protein metabolic processGO:00512483910.036
positive regulation of cellular amine metabolic processGO:003324070.036
regulation of mitotic cell cycleGO:00073461890.035
apical junction assemblyGO:0043297190.035
regulation of transferase activityGO:00513383550.034
Human
vesicle mediated transportGO:00161923710.033
regulation of cellular component movementGO:00512703340.033
regulation of ras protein signal transductionGO:00465781550.033
Human Fly
intracellular protein transportGO:00068862700.032
cell divisionGO:00513011680.032
single organism cellular localizationGO:19025803320.032
locomotory behaviorGO:000762610.032
nervous system developmentGO:00073992930.032
Human Fly
chemical homeostasisGO:00488783060.031
negative regulation of protein modification processGO:00314002000.031
positive regulation of mitotic cell cycleGO:0045931600.030
positive regulation of cell divisionGO:0051781590.030
ameboidal type cell migrationGO:00016671350.030
cytoplasmic transportGO:00164823790.029
regulation of cell divisionGO:00513021160.029
response to oxidative stressGO:00069791210.029
regulation of cellular component biogenesisGO:00440872810.029
Human
regulation of purine nucleotide catabolic processGO:00331212050.028
glycosyl compound catabolic processGO:19016584130.028
ion transmembrane transportGO:00342203380.027
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of establishment of protein localizationGO:00702012420.026
regulation of response to woundingGO:19030341010.026
cell projection organizationGO:00300302520.026
Human Fly
rab protein signal transductionGO:003248240.026
transmembrane transportGO:00550853990.025
regulation of protein kinase activityGO:00458592890.025
Human
response to abiotic stimulusGO:00096283360.025
regulation of mapk cascadeGO:00434082620.025
Human
regenerationGO:003109940.025
cellular response to endogenous stimulusGO:00714953360.024
Human
cell adhesionGO:00071553250.024
protein targetingGO:00066051870.024
neuromuscular junction developmentGO:000752830.024
cell cell junction assemblyGO:0007043250.024
positive regulation of nucleotide metabolic processGO:00459812300.023
cell cell junction organizationGO:0045216690.023
Fly
response to woundingGO:00096111680.023
wound healingGO:00420601150.023
maintenance of locationGO:00512351120.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
positive regulation of cellular component organizationGO:00511303760.023
Human
positive regulation of rab gtpase activityGO:0032851390.023
neurogenesisGO:00220081690.022
Human Fly
regulation of nucleotide catabolic processGO:00308112050.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
mapk cascadeGO:00001652880.022
Human Fly
immune effector processGO:00022521590.022
microtubule based processGO:00070172100.022
peptidyl threonine modificationGO:0018210450.021
protein catabolic processGO:00301633250.021
regulation of gtp catabolic processGO:00331241800.021
protein processingGO:00164852260.021
membrane organizationGO:00610242920.021
positive regulation of protein phosphorylationGO:00019343130.021
Human
cell projection morphogenesisGO:00488581290.021
Human Fly
innate immune responseGO:00450871780.021
segmentationGO:003528240.021
chromatin organizationGO:00063253510.021
generation of neuronsGO:00486991520.021
Human Fly
anterior posterior axis specificationGO:000994820.021
posttranscriptional regulation of gene expressionGO:00106082130.021
signal transduction by phosphorylationGO:00230142970.021
Human Fly
organonitrogen compound biosynthetic processGO:19015662000.021
epithelium migrationGO:00901321190.020
regulation of protein localizationGO:00328802960.020
hindbrain developmentGO:003090230.020
regulation of cellular response to stressGO:00801352440.020
protein localization to organelleGO:00333652800.020
regulation of cell morphogenesisGO:00226041530.020
Human Fly
epithelial cell migrationGO:00106311190.020
negative regulation of hydrolase activityGO:00513461820.020
cellular chemical homeostasisGO:00550821800.020
single organism membrane organizationGO:00448022680.020
nucleoside triphosphate catabolic processGO:00091433940.019
neuroblast proliferationGO:000740540.019
tissue migrationGO:00901301190.019
cellular macromolecular complex assemblyGO:00346223240.019
organelle assemblyGO:00709251760.019
histone threonine phosphorylationGO:003540570.019
regulation of proteolysisGO:00301622930.019
negative regulation of apoptotic processGO:00430663160.018
protein maturationGO:00516042330.018
t cell differentiation in thymusGO:003307740.018
defense responseGO:00069523150.018
regulation of rab protein signal transductionGO:0032483390.018
protein acylationGO:00435431380.018
neuron projection developmentGO:00311751060.018
Human Fly
response to external biotic stimulusGO:00432072610.018
positive regulation of apoptotic processGO:00430652460.018
Human
cell cycle phase transitionGO:00447701730.018
cellular response to organic cyclic compoundGO:00714071270.018
Human
cellular response to dna damage stimulusGO:00069743790.018
regulation of small gtpase mediated signal transductionGO:00510561560.018
Human Fly
inorganic ion transmembrane transportGO:00986602310.018
spermatid developmentGO:000728640.018
cellular response to abiotic stimulusGO:00712141170.017
regulation of rab gtpase activityGO:0032313390.017
blastoderm segmentationGO:000735020.017
carbohydrate metabolic processGO:00059752070.017
immune responseGO:00069553070.017
negative regulation of intracellular signal transductionGO:19025321830.017
carbohydrate derivative biosynthetic processGO:19011372070.017
cellular macromolecule catabolic processGO:00442653800.017
regulation of kinase activityGO:00435493140.017
Human
negative regulation of cellular amino acid metabolic processGO:004576320.017
negative regulation of cellular component organizationGO:00511292350.017
Human
negative regulation of cellular amine metabolic processGO:003323930.017
cellular homeostasisGO:00197251960.017
regulation of protein transportGO:00512232130.017
positive regulation of cell cycleGO:00457871400.017
cell morphogenesis involved in differentiationGO:00009041440.017
Human Fly
neural tube formationGO:000184130.016
regulation of intracellular transportGO:00323861950.016
cellular protein catabolic processGO:00442572610.016
positive regulation of hydrolase activityGO:00513453310.016
negative regulation of cell proliferationGO:00082852280.016
Human
spermatid differentiationGO:004851540.016
mitotic cell cycle phase transitionGO:00447721620.016
covalent chromatin modificationGO:00165692540.016
regulation of cytoskeleton organizationGO:00514931770.016
Human
oocyte developmentGO:004859910.016
neuron differentiationGO:00301821380.016
Human Fly
leukocyte activationGO:00453211640.016
regulation of response to external stimulusGO:00321012220.016
regulation of rho gtpase activityGO:0032319660.016
cation transportGO:00068123310.016
actin cytoskeleton organizationGO:00300362070.016
Human
cation homeostasisGO:00550801890.016
cation transmembrane transportGO:00986552380.016
oocyte differentiationGO:000999420.016
mitotic cell cycle processGO:19030472860.016
positive regulation of transportGO:00510503360.016
regulation of gtpase activityGO:00430871800.016
neurological system processGO:00508771630.016
negative regulation of cell deathGO:00605483450.015
cellular component morphogenesisGO:00329893140.015
Human Fly
nerve developmentGO:002167540.015
cellular response to growth factor stimulusGO:00713631970.015
protein localization to membraneGO:00726571600.015
cell part morphogenesisGO:00329901370.015
Human Fly
response to other organismGO:00517072610.015
internal protein amino acid acetylationGO:00064751010.015
apoptotic signaling pathwayGO:00971902680.015
regulation of protein processingGO:00706131500.015
positive regulation of cell adhesionGO:0045785840.015
positive regulation of immune system processGO:00026842830.015
rna processingGO:00063962550.015
cell activationGO:00017752130.015
phosphatidylinositol 3 kinase signalingGO:0014065480.015
response to inorganic substanceGO:00100351270.015
ion homeostasisGO:00508012300.015
negative regulation of programmed cell deathGO:00430693210.015
protein acetylationGO:00064731160.015
nuclear transportGO:00511691790.014
microtubule cytoskeleton organizationGO:00002261760.014
protein modification by small protein conjugationGO:00324463420.014
reproductive processGO:00224141060.014
Fly
memoryGO:000761330.014
inorganic cation transmembrane transportGO:00986621940.014
cellular response to nitrogen compoundGO:19016991440.014
Human
regulation of protein complex assemblyGO:00432541470.014
nucleocytoplasmic transportGO:00069131760.014
positive regulation of organelle organizationGO:00106381950.014
Human
nitrogen compound transportGO:00717051910.014
response to biotic stimulusGO:00096072760.014
head developmentGO:00603221080.014
regulation of protein serine threonine kinase activityGO:00719001790.014
Human
regulation of protein catabolic processGO:00421761550.013
peptidyl lysine modificationGO:00182051440.013
regulation of hormone levelsGO:00108171250.013
hormone metabolic processGO:0042445610.013
secretionGO:00469032540.013
regulation of synaptic plasticityGO:004816730.013
positive regulation of cell deathGO:00109422630.013
Human
atp metabolic processGO:00460341760.013
cellular lipid metabolic processGO:00442553030.013
cell cell signalingGO:00072671550.013
negative regulation of kinase activityGO:00336731060.013
negative regulation of transportGO:00510511760.013
regulation of vesicle mediated transportGO:00606271300.013
protein ubiquitinationGO:00165673140.013
single organism carbohydrate metabolic processGO:00447231930.013
regulation of endopeptidase activityGO:00525481700.013
positive regulation of protein kinase activityGO:00458601900.013
Human
internal peptidyl lysine acetylationGO:0018393970.013
cell projection assemblyGO:00300311260.013
Fly
establishment of protein localization to membraneGO:00901501210.012
negative regulation of phosphorylationGO:00423261740.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
secretion by cellGO:00329402260.012
regulation of peptidase activityGO:00525471800.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of cell projection organizationGO:00313441070.012
Human
anatomical structure formation involved in morphogenesisGO:00486462840.012
Human
negative regulation of protein processingGO:00109551420.012
embryonic epithelial tube formationGO:000183840.012
response to nitrogen compoundGO:19016981840.012
Human
regulation of protein maturationGO:19033171500.012
heart developmentGO:0007507950.012
rna interferenceGO:001624640.012
hemopoiesisGO:00300971800.012
Fly
cellular response to reactive oxygen speciesGO:0034614500.012
chromatin modificationGO:00165682980.012
central nervous system developmentGO:00074171230.012
peripheral nervous system developmentGO:000742220.012
plasma membrane organizationGO:00070091150.012
proteasomal protein catabolic processGO:00104981760.012
negative regulation of rho gtpase activityGO:003425940.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
metal ion homeostasisGO:00550651690.012
response to hypoxiaGO:0001666960.012
primary neural tube formationGO:001402030.012
compound eye developmentGO:004874910.012
Fly
photoreceptor cell differentiationGO:004653020.012
Fly
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
Human
oxidation reduction processGO:00551143960.012
regulation of growthGO:00400081650.012
cellular metal ion homeostasisGO:00068751460.012
actin cytoskeleton reorganizationGO:0031532370.011
Human
metal ion transportGO:00300012720.011
organelle fissionGO:00482851490.011
regulation of anatomical structure morphogenesisGO:00226032860.011
Human Fly
lipid biosynthetic processGO:00086101770.011
tripartite regional subdivisionGO:000735120.011
regulation of meiotic cell cycleGO:005144540.011
embryo developmentGO:00097901230.011
Fly
response to organic cyclic compoundGO:00140702040.011
Human
associative learningGO:000830610.011
negative regulation of protein maturationGO:19033181420.011
negative regulation of cell cycleGO:00457861930.011
reproductive system developmentGO:0061458560.011
Fly
blood vessel developmentGO:00015681720.011
Human
rhythmic behaviorGO:000762220.011
sensory perceptionGO:00076001030.011
cell growthGO:00160491600.011
circadian behaviorGO:004851220.011
endomembrane system organizationGO:00102561960.011
reactive oxygen species metabolic processGO:0072593750.011
reactive oxygen species biosynthetic processGO:190340940.011
regulation of dephosphorylationGO:0035303960.011
establishment of protein localization to organelleGO:00725941720.011
regulation of defense responseGO:00313471540.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
inositol lipid mediated signalingGO:0048017550.011
protein kinase b signalingGO:0043491690.011
cellular ion homeostasisGO:00068731680.011
meiosis iGO:000712740.011
immune response activating cell surface receptor signaling pathwayGO:0002429450.011
negative regulation of organelle organizationGO:00106391260.011
neurotransmitter secretionGO:000726940.011
cell fate determinationGO:000170930.011
immune response regulating signaling pathwayGO:0002764970.011
cellular hormone metabolic processGO:0034754410.011
regulation of secretionGO:00510461940.011
regulation of membrane potentialGO:0042391950.011
viral processGO:00160321460.011
tissue regenerationGO:004224630.011
immune response activating signal transductionGO:0002757900.011
histone acetylationGO:0016573930.011
epithelial cell differentiationGO:00308551410.011
Human
positive regulation of developmental processGO:00510943140.010
Human
negative regulation of cell differentiationGO:00455961710.010
Human Fly
regulation of chromosome organizationGO:00330441030.010
reactive nitrogen species metabolic processGO:200105730.010
tube closureGO:006060630.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
positive regulation of synaptic transmissionGO:005080640.010
negative regulation of cellular catabolic processGO:0031330830.010
autophagyGO:0006914880.010
mrna metabolic processGO:00160711750.010
cellular protein complex assemblyGO:00436231880.010
g protein coupled receptor signaling pathwayGO:00071862070.010
Human
ribonucleoside monophosphate metabolic processGO:00091611870.010
response to oxygen levelsGO:00704821000.010
somitogenesisGO:000175620.010
chromosome segregationGO:00070591140.010
stem cell divisionGO:001714520.010
glycoprotein metabolic processGO:00091001100.010
multi organism cellular processGO:00447641560.010
response to axon injuryGO:004867810.010
cell matrix adhesionGO:0007160850.010
peptidyl tyrosine phosphorylationGO:00181081700.010
protein oligomerizationGO:00512591730.010
negative regulation of multicellular organismal processGO:00512413170.010
Human

RAPGEF6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.020
nervous system diseaseDOID:8634310.020
central nervous system diseaseDOID:3311860.020
immune system diseaseDOID:29141550.017
sensory system diseaseDOID:00501552030.017
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
musculoskeletal system diseaseDOID:172230.014
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
disease of cellular proliferationDOID:145661740.014
inherited metabolic disorderDOID:6552420.013
neurodegenerative diseaseDOID:12891020.012
retinal diseaseDOID:56791180.012
connective tissue diseaseDOID:651090.010