Homo sapiens

218 known processes

RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

(Aliases: CAMP-GEFI,EPAC1,bcm910,EPAC,HSU79275,MGC21410)

RAPGEF3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.084
purine containing compound catabolic processGO:00725234110.082
cation transportGO:00068123310.079
response to oxygen containing compoundGO:19017003690.061
nucleoside phosphate catabolic processGO:19012924120.060
amine metabolic processGO:0009308440.059
ribonucleotide catabolic processGO:00092614050.058
purine nucleoside catabolic processGO:00061523980.058
regulation of cellular amine metabolic processGO:0033238110.057
post embryonic developmentGO:000979120.057
transmembrane transportGO:00550853990.056
organophosphate catabolic processGO:00464344300.056
regulation of nucleotide metabolic processGO:00061402690.055
purine nucleotide catabolic processGO:00061954050.054
purine ribonucleotide catabolic processGO:00091544040.054
regulation of cellular ketone metabolic processGO:0010565500.053
anion transportGO:00068201610.051
nitrogen compound transportGO:00717051910.050
locomotory behaviorGO:000762610.050
system processGO:00030083490.050
positive regulation of cellular amine metabolic processGO:003324070.050
regulation of purine nucleotide metabolic processGO:19005422640.049
cellular amine metabolic processGO:0044106410.049
nucleotide catabolic processGO:00091664080.048
positive regulation of phosphorylationGO:00423273940.047
Human
cellular amino acid metabolic processGO:00065201160.045
secretionGO:00469032540.045
regulation of cellular amino acid metabolic processGO:000652160.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
cell adhesionGO:00071553250.044
positive regulation of purine nucleotide metabolic processGO:19005442270.044
purine ribonucleoside metabolic processGO:00461284370.043
cyclic nucleotide metabolic processGO:0009187820.042
nucleoside triphosphate metabolic processGO:00091414220.042
nucleoside catabolic processGO:00091644080.040
response to abiotic stimulusGO:00096283360.039
purine ribonucleoside catabolic processGO:00461303980.039
ras protein signal transductionGO:0007265730.039
female gamete generationGO:000729220.039
chemical homeostasisGO:00488783060.038
positive regulation of cellular catabolic processGO:00313312840.038
biological adhesionGO:00226103310.038
cellular response to endogenous stimulusGO:00714953360.037
nucleoside triphosphate catabolic processGO:00091433940.037
multicellular organismal agingGO:001025930.037
regulation of locomotionGO:00400123290.037
metal ion transportGO:00300012720.037
positive regulation of nucleotide metabolic processGO:00459812300.036
negative regulation of transportGO:00510511760.036
lipid metabolic processGO:00066293810.035
positive regulation of protein phosphorylationGO:00019343130.035
Human
small gtpase mediated signal transductionGO:0007264780.035
oogenesisGO:004847720.034
ribonucleoside catabolic processGO:00424544060.034
segmentationGO:003528240.034
regulation of kinase activityGO:00435493140.034
Human
response to other organismGO:00517072610.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
ribonucleoside triphosphate metabolic processGO:00091994120.033
regenerationGO:003109940.033
circulatory system developmentGO:00723592620.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
ribonucleoside triphosphate catabolic processGO:00092033910.032
cation homeostasisGO:00550801890.032
positive regulation of hydrolase activityGO:00513453310.032
regulation of cell migrationGO:00303342890.032
cellular lipid metabolic processGO:00442553030.032
response to organic cyclic compoundGO:00140702040.032
determination of adult lifespanGO:000834020.031
calcium ion transportGO:00068161470.031
organophosphate biosynthetic processGO:00904071630.031
ion transmembrane transportGO:00342203380.031
inorganic ion transmembrane transportGO:00986602310.031
negative regulation of catalytic activityGO:00430863350.031
purine nucleoside triphosphate catabolic processGO:00091463920.030
cardiovascular system developmentGO:00723582620.030
carbohydrate derivative biosynthetic processGO:19011372070.030
cellular response to oxygen containing compoundGO:19017012760.030
regulation of transferase activityGO:00513383550.030
Human
actin filament based processGO:00300292240.029
regulation of secretionGO:00510461940.029
regulation of secretion by cellGO:19035301770.029
glycosyl compound catabolic processGO:19016584130.029
response to nitrogen compoundGO:19016981840.029
rho protein signal transductionGO:0007266260.029
divalent metal ion transportGO:00708381520.029
g protein coupled receptor signaling pathwayGO:00071862070.029
Human
positive regulation of transportGO:00510503360.028
organonitrogen compound biosynthetic processGO:19015662000.028
negative regulation of multicellular organismal processGO:00512413170.028
Human
purine nucleoside triphosphate metabolic processGO:00091444120.028
cell morphogenesisGO:00009022960.028
Human
organic anion transportGO:00157111030.028
vasculature developmentGO:00019441810.028
regulation of protein localizationGO:00328802960.028
regulation of anatomical structure morphogenesisGO:00226032860.028
cytoplasmic transportGO:00164823790.028
carbohydrate metabolic processGO:00059752070.027
regulation of nucleoside metabolic processGO:00091182090.027
negative regulation of cellular protein metabolic processGO:00322693530.027
camp biosynthetic processGO:0006171470.027
metal ion homeostasisGO:00550651690.027
regulation of cell differentiationGO:00455953930.027
Human
regulation of cellular component movementGO:00512703340.027
response to woundingGO:00096111680.027
negative regulation of developmental processGO:00510932470.027
Human
positive regulation of cellular component organizationGO:00511303760.027
anatomical structure formation involved in morphogenesisGO:00486462840.027
regulation of cellular component biogenesisGO:00440872810.027
positive regulation of catabolic processGO:00098963100.027
response to biotic stimulusGO:00096072760.027
camp metabolic processGO:0046058610.027
ion homeostasisGO:00508012300.026
gtp catabolic processGO:00061842370.026
response to cytokineGO:00340972320.026
response to growth factorGO:00708482050.026
secretion by cellGO:00329402260.026
response to external biotic stimulusGO:00432072610.026
immune responseGO:00069553070.025
positive regulation of protein kinase activityGO:00458601900.025
Human
neuromuscular junction developmentGO:000752830.025
membrane organizationGO:00610242920.025
regulation of small gtpase mediated signal transductionGO:00510561560.025
cellular response to organic cyclic compoundGO:00714071270.025
enzyme linked receptor protein signaling pathwayGO:00071673030.025
guanosine containing compound catabolic processGO:19010692390.024
neurological system processGO:00508771630.024
cyclic nucleotide biosynthetic processGO:0009190610.024
cellular homeostasisGO:00197251960.024
defense responseGO:00069523150.024
single organism cellular localizationGO:19025803320.024
memoryGO:000761330.024
gtp metabolic processGO:00460392390.024
positive regulation of immune system processGO:00026842830.024
regulation of nucleotide catabolic processGO:00308112050.024
regulation of cell adhesionGO:00301551660.024
single organism carbohydrate metabolic processGO:00447231930.024
cellular macromolecular complex assemblyGO:00346223240.023
guanosine containing compound metabolic processGO:19010682440.023
negative regulation of cellular component organizationGO:00511292350.023
Human
anterior posterior axis specificationGO:000994820.023
blastoderm segmentationGO:000735020.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of protein kinase activityGO:00458592890.023
Human
purine ribonucleotide biosynthetic processGO:0009152790.023
cellular response to growth factor stimulusGO:00713631970.023
positive regulation of gtpase activityGO:00435471660.022
actin cytoskeleton organizationGO:00300362070.022
negative regulation of cell differentiationGO:00455961710.022
Human
maintenance of locationGO:00512351120.022
cell developmentGO:00484683280.022
negative regulation of locomotionGO:00400131180.022
nucleoside phosphate biosynthetic processGO:19012931090.022
regulation of establishment of protein localizationGO:00702012420.022
wound healingGO:00420601150.022
oxidation reduction processGO:00551143960.022
intracellular protein transportGO:00068862700.022
regulation of hormone levelsGO:00108171250.022
cellular cation homeostasisGO:00300031630.022
regulation of gtp catabolic processGO:00331241800.022
negative regulation of cell deathGO:00605483450.022
regulation of mapk cascadeGO:00434082620.022
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.022
vesicle mediated transportGO:00161923710.022
apoptotic signaling pathwayGO:00971902680.021
divalent inorganic cation transportGO:00725111580.021
positive regulation of nucleotide catabolic processGO:00308131850.021
negative regulation of apoptotic processGO:00430663160.021
cell cell signalingGO:00072671550.021
cellular calcium ion homeostasisGO:00068741170.021
single organism membrane organizationGO:00448022680.021
response to hormoneGO:00097251750.021
matingGO:000761810.021
cellular response to nitrogen compoundGO:19016991440.021
positive regulation of cell proliferationGO:00082843010.021
regulation of purine nucleotide catabolic processGO:00331212050.021
cellular divalent inorganic cation homeostasisGO:00725031280.020
protein localization to organelleGO:00333652800.020
cyclic purine nucleotide metabolic processGO:0052652600.020
negative regulation of phosphate metabolic processGO:00459362670.020
ribonucleotide biosynthetic processGO:0009260810.020
negative regulation of protein metabolic processGO:00512483910.020
regulation of protein serine threonine kinase activityGO:00719001790.020
Human
oocyte developmentGO:004859910.020
response to bacteriumGO:00096171440.020
cation transmembrane transportGO:00986552380.019
cell type specific apoptotic processGO:00972851250.019
Human
cellular ion homeostasisGO:00068731680.019
positive regulation of nucleoside metabolic processGO:00459791860.019
purine containing compound biosynthetic processGO:0072522880.019
oocyte differentiationGO:000999420.019
regulation of cyclic nucleotide metabolic processGO:0030799630.019
nucleotide biosynthetic processGO:00091651090.019
negative regulation of cell migrationGO:00303361020.019
inorganic cation transmembrane transportGO:00986621940.019
regulation of gtpase activityGO:00430871800.019
angiogenesisGO:00015251470.019
morphogenesis of embryonic epitheliumGO:001633140.019
response to lipidGO:00339932060.018
cell activationGO:00017752130.018
growthGO:00400072020.018
innate immune responseGO:00450871780.018
signal transduction by phosphorylationGO:00230142970.018
Human
protein catabolic processGO:00301633250.018
protein maturationGO:00516042330.018
sensory perception of painGO:001923340.018
regulation of cell cycle processGO:00105642660.018
negative regulation of synaptic transmissionGO:005080520.018
positive regulation of cell deathGO:00109422630.018
Human
cellular protein complex assemblyGO:00436231880.018
embryonic epithelial tube formationGO:000183840.018
mitotic cell cycle processGO:19030472860.018
adult locomotory behaviorGO:000834410.018
mapk cascadeGO:00001652880.018
Human
response to organonitrogen compoundGO:00102431560.018
positive regulation of mapk cascadeGO:00434101900.018
Human
sensory perceptionGO:00076001030.017
cellular response to cytokine stimulusGO:00713451810.017
circulatory system processGO:00030131130.017
positive regulation of developmental processGO:00510943140.017
positive regulation of gtp catabolic processGO:00331261660.017
nervous system developmentGO:00073992930.017
Human
cellular response to organonitrogen compoundGO:00714171240.017
dephosphorylationGO:00163112090.017
protein processingGO:00164852260.017
regulation of protein complex assemblyGO:00432541470.017
calcium ion homeostasisGO:00550741220.017
mitotic cell cycleGO:00002783260.017
response to inorganic substanceGO:00100351270.017
cellular metal ion homeostasisGO:00068751460.017
regulation of cell motilityGO:20001452990.017
ribose phosphate biosynthetic processGO:0046390820.017
regulation of cellular response to stressGO:00801352440.016
positive regulation of apoptotic processGO:00430652460.016
Human
cellular chemical homeostasisGO:00550821800.016
negative regulation of cellular component movementGO:00512711060.016
regulation of immune responseGO:00507762010.016
negative regulation of cell motilityGO:20001461040.016
negative regulation of hydrolase activityGO:00513461820.016
sequestering of calcium ionGO:0051208170.016
spermatid differentiationGO:004851540.016
negative regulation of programmed cell deathGO:00430693210.016
peripheral nervous system developmentGO:000742220.016
peptidyl tyrosine modificationGO:00182121700.016
regulation of ras protein signal transductionGO:00465781550.016
cell projection organizationGO:00300302520.016
Human
blood vessel developmentGO:00015681720.016
lipid localizationGO:00108761060.016
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.016
positive regulation of ras gtpase activityGO:00323201170.016
negative regulation of cell proliferationGO:00082852280.015
Human
regulation of growthGO:00400081650.015
divalent inorganic cation homeostasisGO:00725071360.015
regulation of ion transportGO:00432691890.015
regulation of cell cycleGO:00517263930.015
response to purine containing compoundGO:0014074400.015
protein localization to membraneGO:00726571600.015
positive regulation of transferase activityGO:00513472270.015
Human
regulation of response to external stimulusGO:00321012220.015
regulation of intracellular transportGO:00323861950.015
cellular macromolecule catabolic processGO:00442653800.015
regulation of ras gtpase activityGO:00323181280.015
response to radiationGO:00093141510.015
regulation of cell morphogenesisGO:00226041530.015
Human
negative regulation of cellular amine metabolic processGO:003323930.015
positive regulation of kinase activityGO:00336742040.015
Human
cell substrate adhesionGO:00315891320.015
regulation of angiogenesisGO:0045765920.015
regulation of cell developmentGO:00602841610.015
Human
cellular response to dna damage stimulusGO:00069743790.015
tripartite regional subdivisionGO:000735120.015
neuroblast proliferationGO:000740540.014
negative regulation of protein maturationGO:19033181420.014
microtubule based processGO:00070172100.014
regulation of proteolysisGO:00301622930.014
cellular protein catabolic processGO:00442572610.014
negative regulation of immune system processGO:00026831360.014
positive regulation of ion transportGO:0043270870.014
endocytosisGO:00068971590.014
lipid biosynthetic processGO:00086101770.014
protein targetingGO:00066051870.014
leukocyte activationGO:00453211640.014
negative regulation of intracellular signal transductionGO:19025321830.014
response to axon injuryGO:004867810.014
endomembrane system organizationGO:00102561960.014
spermatid developmentGO:000728640.014
regulation of protein maturationGO:19033171500.014
hindbrain developmentGO:003090230.014
regulation of cell activationGO:00508651250.014
regulation of defense responseGO:00313471540.014
wnt signaling pathwayGO:00160551560.014
protein ubiquitinationGO:00165673140.014
sequestering of metal ionGO:0051238240.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
positive regulation of cytosolic calcium ion concentrationGO:0007204820.014
microtubule cytoskeleton organizationGO:00002261760.014
response to metal ionGO:0010038840.014
purine nucleotide biosynthetic processGO:0006164840.014
regulation of body fluid levelsGO:0050878990.014
regulation of protein transportGO:00512232130.014
positive regulation of cytokine productionGO:00018191670.014
ameboidal type cell migrationGO:00016671350.013
positive regulation of camp biosynthetic processGO:0030819350.013
negative regulation of protein modification processGO:00314002000.013
cytosolic calcium ion homeostasisGO:0051480890.013
positive regulation of immune responseGO:00507781590.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
anterior posterior axis specification embryoGO:000859520.013
regulation of cyclic nucleotide biosynthetic processGO:0030802490.013
regulation of multi organism processGO:00439001570.013
compound eye developmentGO:004874910.013
cell fate determinationGO:000170930.013
protein modification by small protein conjugationGO:00324463420.013
peptidyl tyrosine phosphorylationGO:00181081700.013
histone modificationGO:00165702510.013
phospholipid metabolic processGO:0006644990.013
regulation of nucleotide biosynthetic processGO:0030808500.013
positive regulation of programmed cell deathGO:00430682490.013
Human
tissue migrationGO:00901301190.013
nuclear transportGO:00511691790.013
organic hydroxy compound metabolic processGO:19016151470.013
regulation of cytokine productionGO:00018172320.013
rhythmic behaviorGO:000762220.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
multicellular organismal response to stressGO:003355510.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
establishment of protein localization to organelleGO:00725941720.013
blood vessel morphogenesisGO:00485141620.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
reactive oxygen species metabolic processGO:0072593750.013
regulation of protein processingGO:00706131500.013
epithelium developmentGO:00604292270.013
cell growthGO:00160491600.012
monocarboxylic acid metabolic processGO:00327871850.012
tube developmentGO:00352951250.012
regulation of cytoskeleton organizationGO:00514931770.012
regulation of metal ion transportGO:00109591200.012
stem cell divisionGO:001714520.012
negative regulation of phosphorylationGO:00423261740.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
regulation of ion transmembrane transportGO:00347651320.012
regulation of vasculature developmentGO:1901342970.012
glycerolipid metabolic processGO:00464861070.012
positive regulation of cell motilityGO:20001471770.012
cardiac muscle cell contractionGO:008600340.012
nucleocytoplasmic transportGO:00069131760.012
regulation of homeostatic processGO:00328441210.012
protein oligomerizationGO:00512591730.012
epithelial cell migrationGO:00106311190.012
single organismal cell cell adhesionGO:00163371480.012
regulation of cytoplasmic transportGO:19036491490.012
regulation of neural precursor cell proliferationGO:200017740.012
cellular response to abiotic stimulusGO:00712141170.012
negative regulation of transferase activityGO:00513481240.012
response to salt stressGO:000965130.012
organic acid transportGO:0015849650.012
ossificationGO:00015031210.012
epithelial cell differentiationGO:00308551410.012
lipid catabolic processGO:0016042840.012
establishment of protein localization to membraneGO:00901501210.012
positive regulation of secretionGO:00510471160.012
cytokine productionGO:00018162470.012
tissue regenerationGO:004224630.012
negative regulation of secretion by cellGO:1903531520.012
lung alveolus developmentGO:004828640.012
actin filament organizationGO:00070151280.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
regulation of purine nucleotide biosynthetic processGO:1900371500.012
neurotransmitter secretionGO:000726940.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
regulation of hormone secretionGO:0046883570.012
signal releaseGO:0023061700.012
negative regulation of protein processingGO:00109551420.012
regulation of protein catabolic processGO:00421761550.012
negative regulation of catabolic processGO:00098951040.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of leukocyte activationGO:00026941150.012
cell cycle phase transitionGO:00447701730.012
multicellular organismal homeostasisGO:0048871670.012
alcohol metabolic processGO:00060661140.012
sulfur compound metabolic processGO:00067901010.012
posttranscriptional regulation of gene expressionGO:00106082130.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of camp metabolic processGO:0030814520.012
regulation of rho protein signal transductionGO:0035023790.012
negative regulation of proteolysisGO:00458611320.011
protein autophosphorylationGO:00467771230.011
sensory perception of smellGO:000760820.011
plasma membrane organizationGO:00070091150.011
regulation of synaptic plasticityGO:004816730.011
peptide transportGO:0015833740.011
rna processingGO:00063962550.011
cell morphogenesis involved in differentiationGO:00009041440.011
Human
response to fungusGO:000962040.011
positive regulation of cell adhesionGO:0045785840.011
cellular component morphogenesisGO:00329893140.011
Human
neurogenesisGO:00220081690.011
Human
positive regulation of cell migrationGO:00303351720.011
proteasomal protein catabolic processGO:00104981760.011
regulation of transmembrane transportGO:00347621390.011
erk1 and erk2 cascadeGO:00703711040.011
Human
interspecies interaction between organismsGO:00444191560.011
glycoprotein metabolic processGO:00091001100.011
blood circulationGO:00080151130.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of vesicle mediated transportGO:00606271300.011
amide transportGO:0042886760.011
negative regulation of organelle organizationGO:00106391260.011
multi organism cellular processGO:00447641560.011
response to drugGO:0042493810.011
neural tube formationGO:000184130.011
response to molecule of bacterial originGO:0002237820.011
tube closureGO:006060630.011
regulation of wnt signaling pathwayGO:00301111230.011
motor neuron axon guidanceGO:000804520.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
myeloid cell differentiationGO:00300991170.011
protein importGO:00170381300.011
cell projection assemblyGO:00300311260.011
somitogenesisGO:000175620.011
regulation of apoptotic signaling pathwayGO:20012331750.011
positive regulation of synaptic transmissionGO:005080640.011
protein polymerizationGO:0051258710.011
regulation of calcium ion transportGO:0051924790.011
small molecule biosynthetic processGO:00442831570.011
negative regulation of protein kinase activityGO:0006469980.011
organelle assemblyGO:00709251760.011
negative regulation of cell cycleGO:00457861930.011
chemotaxisGO:00069351570.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
Human
mitotic cell cycle phase transitionGO:00447721620.011
chromatin organizationGO:00063253510.011
regulation of feeding behaviorGO:006025930.011
reactive oxygen species biosynthetic processGO:190340940.010
inner ear morphogenesisGO:004247240.010
positive regulation of cellular component movementGO:00512721810.010
primary neural tube formationGO:001402030.010
circadian behaviorGO:004851220.010
organ morphogenesisGO:00098871470.010
negative regulation of secretionGO:0051048580.010
neural tube closureGO:000184330.010
positive regulation of secretion by cellGO:19035321080.010
long term memoryGO:000761620.010
cellular carbohydrate metabolic processGO:0044262840.010
cell matrix adhesionGO:0007160850.010
peptide secretionGO:0002790510.010
immune system developmentGO:00025201950.010
receptor metabolic processGO:0043112810.010
protein localization to nucleusGO:00345041360.010
glial cell migrationGO:000834740.010
positive regulation of organelle organizationGO:00106381950.010
monosaccharide metabolic processGO:0005996740.010
lymphocyte activationGO:00466491330.010
immune effector processGO:00022521590.010
behaviorGO:00076101120.010
cell part morphogenesisGO:00329901370.010
Human
modification dependent protein catabolic processGO:00199412090.010
ubiquitin dependent protein catabolic processGO:00065112060.010
response to oxidative stressGO:00069791210.010

RAPGEF3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.038
disease of metabolismDOID:00146672950.030
inherited metabolic disorderDOID:6552420.021
sensory system diseaseDOID:00501552030.021
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.019
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
connective tissue diseaseDOID:651090.017
organ system cancerDOID:00506861640.017
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014
eye and adnexa diseaseDOID:14921500.014
immune system diseaseDOID:29141550.013
myopathyDOID:4231040.013
neurodegenerative diseaseDOID:12891020.012
eye diseaseDOID:56141490.012
retinal diseaseDOID:56791180.012
urinary system diseaseDOID:18400.010
kidney diseaseDOID:557360.010
cardiovascular system diseaseDOID:12871060.010