Homo sapiens

11 known processes

ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

(Aliases: PEM2,KIAA0424,PEM-2,EIEE8,HPEM-2,COLLYBISTIN)

ARHGEF9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.055
amine metabolic processGO:0009308440.054
cellular amino acid metabolic processGO:00065201160.054
post embryonic developmentGO:000979120.053
regulation of cellular amine metabolic processGO:0033238110.051
regulation of cellular amino acid metabolic processGO:000652160.050
cellular ketone metabolic processGO:0042180800.046
regulation of cellular ketone metabolic processGO:0010565500.044
purine ribonucleoside metabolic processGO:00461284370.042
Human
multicellular organismal agingGO:001025930.041
ribonucleoside triphosphate metabolic processGO:00091994120.041
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
Human
ribonucleoside triphosphate catabolic processGO:00092033910.039
Human
nucleoside phosphate catabolic processGO:19012924120.039
Human
female gamete generationGO:000729220.038
purine ribonucleoside catabolic processGO:00461303980.038
Human
ras protein signal transductionGO:0007265730.038
cellular macromolecule catabolic processGO:00442653800.038
locomotory behaviorGO:000762610.037
single organism cellular localizationGO:19025803320.037
Rat
determination of adult lifespanGO:000834020.036
glycosyl compound catabolic processGO:19016584130.035
Human
purine containing compound catabolic processGO:00725234110.034
Human
ribonucleotide catabolic processGO:00092614050.034
Human
regulation of cellular component movementGO:00512703340.033
Human
regulation of locomotionGO:00400123290.033
Human
transmembrane transportGO:00550853990.033
oogenesisGO:004847720.033
biological adhesionGO:00226103310.032
protein catabolic processGO:00301633250.032
ribonucleoside catabolic processGO:00424544060.032
Human
positive regulation of cellular component organizationGO:00511303760.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
organophosphate catabolic processGO:00464344300.031
Human
positive regulation of transportGO:00510503360.030
ion transmembrane transportGO:00342203380.030
memoryGO:000761330.030
negative regulation of cellular protein metabolic processGO:00322693530.030
nucleotide catabolic processGO:00091664080.030
Human
purine nucleoside triphosphate metabolic processGO:00091444120.030
Human
negative regulation of catalytic activityGO:00430863350.030
nucleoside triphosphate catabolic processGO:00091433940.030
Human
cell adhesionGO:00071553250.030
regulation of cell cycleGO:00517263930.029
purine nucleotide catabolic processGO:00061954050.029
Human
small gtpase mediated signal transductionGO:0007264780.028
metal ion transportGO:00300012720.028
negative regulation of cell deathGO:00605483450.028
regulation of cell motilityGO:20001452990.028
Human
neuromuscular junction developmentGO:000752830.028
cellular protein catabolic processGO:00442572610.027
cytoplasmic transportGO:00164823790.027
negative regulation of protein metabolic processGO:00512483910.027
purine nucleoside catabolic processGO:00061523980.027
Human
nucleoside catabolic processGO:00091644080.027
Human
associative learningGO:000830610.027
nucleoside triphosphate metabolic processGO:00091414220.026
Human
positive regulation of cellular amine metabolic processGO:003324070.026
membrane organizationGO:00610242920.026
Rat
regulation of anatomical structure morphogenesisGO:00226032860.026
system processGO:00030083490.025
segmentationGO:003528240.025
regulation of sequence specific dna binding transcription factor activityGO:00510902110.025
regulation of proteolysisGO:00301622930.025
nervous system developmentGO:00073992930.025
vesicle mediated transportGO:00161923710.025
single organism membrane organizationGO:00448022680.025
Rat
regulation of protein localizationGO:00328802960.024
actin filament based processGO:00300292240.024
protein modification by small protein conjugationGO:00324463420.024
regulation of cell differentiationGO:00455953930.024
response to abiotic stimulusGO:00096283360.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
Human
modification dependent macromolecule catabolic processGO:00436322120.024
regulation of cellular response to stressGO:00801352440.023
negative regulation of programmed cell deathGO:00430693210.023
cellular lipid metabolic processGO:00442553030.023
cation transportGO:00068123310.023
regulation of cell migrationGO:00303342890.023
Human
regulation of transferase activityGO:00513383550.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
Human
cellular response to oxygen containing compoundGO:19017012760.023
cell morphogenesisGO:00009022960.023
adult locomotory behaviorGO:000834410.023
apoptotic signaling pathwayGO:00971902680.022
negative regulation of phosphorus metabolic processGO:00105632670.022
protein localization to organelleGO:00333652800.022
chemical homeostasisGO:00488783060.022
cellular response to dna damage stimulusGO:00069743790.022
response to oxygen containing compoundGO:19017003690.022
intracellular protein transportGO:00068862700.022
cation transmembrane transportGO:00986552380.022
positive regulation of hydrolase activityGO:00513453310.022
Human
defense responseGO:00069523150.022
modification dependent protein catabolic processGO:00199412090.022
hindbrain developmentGO:003090230.022
lipid metabolic processGO:00066293810.022
negative regulation of cellular component organizationGO:00511292350.022
rho protein signal transductionGO:0007266260.021
purine ribonucleotide catabolic processGO:00091544040.021
Human
mapk cascadeGO:00001652880.021
positive regulation of phosphorylationGO:00423273940.021
mitotic cell cycleGO:00002783260.021
cell junction maintenanceGO:003433140.021
gtp metabolic processGO:00460392390.021
Human
single organism cell adhesionGO:00986021790.021
carbohydrate metabolic processGO:00059752070.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
oxidation reduction processGO:00551143960.021
regulation of kinase activityGO:00435493140.021
protein ubiquitinationGO:00165673140.021
inorganic cation transmembrane transportGO:00986621940.021
negative regulation of cellular amine metabolic processGO:003323930.021
cellular component morphogenesisGO:00329893140.021
immune responseGO:00069553070.021
positive regulation of cellular catabolic processGO:00313312840.021
Human
cell projection organizationGO:00300302520.020
Human
embryonic epithelial tube formationGO:000183840.020
carbohydrate derivative biosynthetic processGO:19011372070.020
negative regulation of multicellular organismal processGO:00512413170.020
mitotic cell cycle processGO:19030472860.020
matingGO:000761810.020
morphogenesis of embryonic epitheliumGO:001633140.020
secretion by cellGO:00329402260.020
maintenance of locationGO:00512351120.020
negative regulation of phosphate metabolic processGO:00459362670.020
organonitrogen compound biosynthetic processGO:19015662000.020
guanosine containing compound catabolic processGO:19010692390.020
Human
chromatin organizationGO:00063253510.020
single organismal cell cell adhesionGO:00163371480.019
regulation of nucleotide metabolic processGO:00061402690.019
Human
regenerationGO:003109940.019
cellular homeostasisGO:00197251960.019
protein maturationGO:00516042330.019
proteasomal protein catabolic processGO:00104981760.019
gtp catabolic processGO:00061842370.019
Human
regulation of cellular component biogenesisGO:00440872810.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
positive regulation of protein phosphorylationGO:00019343130.019
dephosphorylationGO:00163112090.019
inorganic ion transmembrane transportGO:00986602310.019
blastoderm segmentationGO:000735020.019
negative regulation of intracellular signal transductionGO:19025321830.019
ion homeostasisGO:00508012300.019
positive regulation of catabolic processGO:00098963100.019
Human
positive regulation of nucleotide metabolic processGO:00459812300.019
Human
regulation of cell morphogenesisGO:00226041530.019
regulation of establishment of protein localizationGO:00702012420.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
regulation of multi organism processGO:00439001570.018
protein localization to membraneGO:00726571600.018
Rat
cell growthGO:00160491600.018
protein processingGO:00164852260.018
endomembrane system organizationGO:00102561960.018
regulation of protein kinase activityGO:00458592890.018
secretionGO:00469032540.018
neurological system processGO:00508771630.018
signal transduction by phosphorylationGO:00230142970.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
single organism carbohydrate metabolic processGO:00447231930.018
viral processGO:00160321460.018
chromatin modificationGO:00165682980.018
cellular protein complex assemblyGO:00436231880.018
anterior posterior axis specificationGO:000994820.018
cellular macromolecular complex assemblyGO:00346223240.018
regulation of protein transportGO:00512232130.018
negative regulation of apoptotic processGO:00430663160.018
regulation of intracellular transportGO:00323861950.018
regulation of mapk cascadeGO:00434082620.017
nucleoside monophosphate metabolic processGO:00091231910.017
histone modificationGO:00165702510.017
negative regulation of developmental processGO:00510932470.017
oocyte developmentGO:004859910.017
positive regulation of cell deathGO:00109422630.017
protein targetingGO:00066051870.017
regulation of secretionGO:00510461940.017
oocyte differentiationGO:000999420.017
cell projection assemblyGO:00300311260.017
Human
regulation of secretion by cellGO:19035301770.017
posttranscriptional regulation of gene expressionGO:00106082130.017
regulation of apoptotic signaling pathwayGO:20012331750.017
neurogenesisGO:00220081690.017
monovalent inorganic cation transportGO:00156721280.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
spermatid differentiationGO:004851540.016
negative regulation of cell proliferationGO:00082852280.016
rhythmic behaviorGO:000762220.016
cell cell junction maintenanceGO:004521740.016
interspecies interaction between organismsGO:00444191560.016
positive regulation of nucleotide catabolic processGO:00308131850.016
Human
cardiac muscle cell contractionGO:008600340.016
cellular response to endogenous stimulusGO:00714953360.016
atp metabolic processGO:00460341760.016
growthGO:00400072020.016
negative regulation of transportGO:00510511760.016
regulation of synaptic plasticityGO:004816730.016
neurotransmitter secretionGO:000726940.016
regulation of gtpase activityGO:00430871800.016
Human
microtubule based processGO:00070172100.016
positive regulation of synaptic transmissionGO:005080640.016
actin cytoskeleton organizationGO:00300362070.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
innate immune responseGO:00450871780.016
protein polyubiquitinationGO:00002091100.016
regulation of cell cycle processGO:00105642660.016
organophosphate biosynthetic processGO:00904071630.016
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
reactive oxygen species biosynthetic processGO:190340940.015
positive regulation of transferase activityGO:00513472270.015
viral life cycleGO:00190581320.015
neural tube formationGO:000184130.015
positive regulation of apoptotic processGO:00430652460.015
divalent metal ion transportGO:00708381520.015
regulation of cell growthGO:00015581350.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
negative regulation of protein modification processGO:00314002000.015
generation of neuronsGO:00486991520.015
multi organism cellular processGO:00447641560.015
regulation of growthGO:00400081650.015
regulation of ras protein signal transductionGO:00465781550.015
Human
muscle system processGO:0003012810.015
photoreceptor cell differentiationGO:004653020.015
ubiquitin dependent protein catabolic processGO:00065112060.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
positive regulation of cell proliferationGO:00082843010.015
peripheral nervous system developmentGO:000742220.015
positive regulation of programmed cell deathGO:00430682490.015
microtubule cytoskeleton organizationGO:00002261760.015
sensory perception of painGO:001923340.015
positive regulation of cellular component movementGO:00512721810.015
positive regulation of developmental processGO:00510943140.015
positive regulation of nucleoside metabolic processGO:00459791860.015
Human
anterior posterior axis specification embryoGO:000859520.015
guanosine containing compound metabolic processGO:19010682440.015
Human
metencephalon developmentGO:002203720.015
tripartite regional subdivisionGO:000735120.014
establishment of protein localization to membraneGO:00901501210.014
cellular chemical homeostasisGO:00550821800.014
small molecule catabolic processGO:0044282920.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.014
Human
i kappab kinase nf kappab signalingGO:00072491660.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
establishment of protein localization to organelleGO:00725941720.014
cell developmentGO:00484683280.014
endosomal transportGO:00161971290.014
positive regulation of cell motilityGO:20001471770.014
compound eye developmentGO:004874910.014
covalent chromatin modificationGO:00165692540.014
spermatid developmentGO:000728640.014
reactive nitrogen species metabolic processGO:200105730.014
response to nitrogen compoundGO:19016981840.014
actin filament based movementGO:0030048170.014
meiotic chromosome segregationGO:004513240.014
regulation of cytoskeleton organizationGO:00514931770.014
regulation of gtp catabolic processGO:00331241800.014
Human
sequestering of metal ionGO:0051238240.014
mitochondrion organizationGO:00070051560.014
circadian behaviorGO:004851220.014
cation homeostasisGO:00550801890.014
positive regulation of cell migrationGO:00303351720.014
negative regulation of phosphorylationGO:00423261740.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
regulation of purine nucleotide catabolic processGO:00331212050.014
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.014
Human
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
positive regulation of kinase activityGO:00336742040.014
regulation of ion transportGO:00432691890.014
regulation of cell developmentGO:00602841610.014
phospholipid metabolic processGO:0006644990.014
divalent inorganic cation transportGO:00725111580.014
protein oligomerizationGO:00512591730.014
regulation of transmembrane transportGO:00347621390.013
glycerolipid metabolic processGO:00464861070.013
regulation of protein catabolic processGO:00421761550.013
visual behaviorGO:000763220.013
response to external biotic stimulusGO:00432072610.013
regulation of neural precursor cell proliferationGO:200017740.013
positive regulation of cell differentiationGO:00455972110.013
regulation of purine nucleotide metabolic processGO:19005422640.013
Human
regulation of response to external stimulusGO:00321012220.013
neuron developmentGO:00486661130.013
positive regulation of proteolysisGO:00458621420.013
cellular cation homeostasisGO:00300031630.013
regulation of protein processingGO:00706131500.013
cell junction organizationGO:0034330790.013
regulation of protein serine threonine kinase activityGO:00719001790.013
cerebellum developmentGO:002154920.013
nitrogen compound transportGO:00717051910.013
response to organonitrogen compoundGO:00102431560.013
positive regulation of cell cycleGO:00457871400.013
long term memoryGO:000761620.013
actin mediated cell contractionGO:0070252120.013
response to cytokineGO:00340972320.013
lipid biosynthetic processGO:00086101770.013
positive regulation of organelle organizationGO:00106381950.013
regulation of protein maturationGO:19033171500.013
glycoprotein metabolic processGO:00091001100.013
positive regulation of cellular component biogenesisGO:00440891580.013
regulation of neurotransmitter secretionGO:004692830.013
response to biotic stimulusGO:00096072760.013
regulation of vesicle mediated transportGO:00606271300.013
negative regulation of protein processingGO:00109551420.013
wnt signaling pathwayGO:00160551560.013
cell cell junction organizationGO:0045216690.012
positive regulation of gtpase activityGO:00435471660.012
Human
positive regulation of immune system processGO:00026842830.012
positive regulation of locomotionGO:00400171860.012
protein acylationGO:00435431380.012
cell projection morphogenesisGO:00488581290.012
metal ion homeostasisGO:00550651690.012
regulation of cytokine productionGO:00018172320.012
regulation of protein complex assemblyGO:00432541470.012
regulation of ion transmembrane transportGO:00347651320.012
calcium ion transportGO:00068161470.012
cell divisionGO:00513011680.012
regulation of nucleotide catabolic processGO:00308112050.012
Human
positive regulation of protein kinase activityGO:00458601900.012
inner ear morphogenesisGO:004247240.012
positive regulation of gtp catabolic processGO:00331261660.012
Human
motor neuron axon guidanceGO:000804520.012
nucleoside monophosphate catabolic processGO:00091251590.012
rna processingGO:00063962550.012
plasma membrane organizationGO:00070091150.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
sequestering of calcium ionGO:0051208170.012
response to growth factorGO:00708482050.012
primary neural tube formationGO:001402030.012
regulation of nucleoside metabolic processGO:00091182090.012
Human
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
morphogenesis of a polarized epitheliumGO:000173830.012
regulation of actin filament based processGO:00329701410.012
cytokine productionGO:00018162470.012
neuron differentiationGO:00301821380.012
actin filament organizationGO:00070151280.012
protein localization to plasma membraneGO:0072659930.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
cellular ion homeostasisGO:00068731680.012
cellular response to growth factor stimulusGO:00713631970.012
tube closureGO:006060630.012
reactive oxygen species metabolic processGO:0072593750.012
circulatory system developmentGO:00723592620.012
cell cycle phase transitionGO:00447701730.012
regulation of homeostatic processGO:00328441210.012
negative regulation of protein phosphorylationGO:00019331400.012
negative regulation of cell cycleGO:00457861930.012
positive regulation of protein transportGO:00512221350.012
response to axon injuryGO:004867810.012
internal protein amino acid acetylationGO:00064751010.012
response to fungusGO:000962040.012
atp catabolic processGO:00062001570.012
regulation of metal ion transportGO:00109591200.012
regulation of transporter activityGO:0032409820.012
regulation of mitotic cell cycleGO:00073461890.011
limbic system developmentGO:002176130.011
visual learningGO:000854210.011
regulation of cell adhesionGO:00301551660.011
regulation of viral processGO:00507921030.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
peptidyl lysine modificationGO:00182051440.011
negative regulation of locomotionGO:00400131180.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
positive regulation of secretionGO:00510471160.011
nuclear transportGO:00511691790.011
cell part morphogenesisGO:00329901370.011
negative regulation of cell migrationGO:00303361020.011
glycerophospholipid metabolic processGO:0006650840.011
organelle assemblyGO:00709251760.011
cell type specific apoptotic processGO:00972851250.011
central nervous system developmentGO:00074171230.011
establishment of planar polarityGO:000173630.011
monocarboxylic acid metabolic processGO:00327871850.011
cell cell signalingGO:00072671550.011
negative regulation of cell differentiationGO:00455961710.011
regulation of actin cytoskeleton organizationGO:00329561160.011
negative regulation of transferase activityGO:00513481240.011
neural tube closureGO:000184330.011
cellular metal ion homeostasisGO:00068751460.011
regulation of ras gtpase activityGO:00323181280.011
Human
establishment or maintenance of cytoskeleton polarityGO:003095230.011
meiosis iGO:000712740.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
organ formationGO:004864530.011
regulation of intracellular protein transportGO:00331571230.011
epithelial cell proliferationGO:00506731280.011
sleepGO:003043120.011
mrna metabolic processGO:00160711750.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
zonula adherens maintenanceGO:004521830.011
regulation of transmembrane transporter activityGO:0022898740.011
organic hydroxy compound metabolic processGO:19016151470.011
epithelium developmentGO:00604292270.011
striated muscle contractionGO:0006941520.011
response to hormoneGO:00097251750.011
neuroblast proliferationGO:000740540.011
mitotic cell cycle phase transitionGO:00447721620.011
spinal cord developmentGO:002151040.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
negative regulation of protein maturationGO:19033181420.011
sensory perception of smellGO:000760820.011
sex determinationGO:000753030.011
response to other organismGO:00517072610.011
rna interferenceGO:001624640.011
regulation of immune responseGO:00507762010.011
cellular carbohydrate metabolic processGO:0044262840.011
negative regulation of proteolysisGO:00458611320.011
startle responseGO:000196430.011
nerve developmentGO:002167540.011
cellular calcium ion homeostasisGO:00068741170.011
muscle contractionGO:0006936730.011
regulation of endopeptidase activityGO:00525481700.010
syncytium formation by plasma membrane fusionGO:000076820.010
regulation of feeding behaviorGO:006025930.010
salivary gland morphogenesisGO:000743540.010
regulation of cytoplasmic transportGO:19036491490.010
alcohol metabolic processGO:00060661140.010
cell morphogenesis involved in differentiationGO:00009041440.010
protein autophosphorylationGO:00467771230.010
cardiovascular system developmentGO:00723582620.010
tissue migrationGO:00901301190.010
response to organic cyclic compoundGO:00140702040.010
divalent inorganic cation homeostasisGO:00725071360.010
methylationGO:00322591060.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
anion transportGO:00068201610.010
release of cytoplasmic sequestered nf kappabGO:000858840.010
establishment or maintenance of bipolar cell polarityGO:006124520.010
dna repairGO:00062811980.010
cellular response to cytokine stimulusGO:00713451810.010
cell fate determinationGO:000170930.010
cofactor metabolic processGO:0051186870.010
protein acetylationGO:00064731160.010
nucleus localizationGO:005164710.010
cellular response to nitrogen compoundGO:19016991440.010
peptidyl serine modificationGO:00182091060.010
endocytosisGO:00068971590.010
melanin metabolic processGO:000658210.010
nucleocytoplasmic transportGO:00069131760.010
neuron projection regenerationGO:003110210.010

ARHGEF9 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.041
inherited metabolic disorderDOID:6552420.037
nervous system diseaseDOID:8634310.027
central nervous system diseaseDOID:3311860.027
sensory system diseaseDOID:00501552030.024
musculoskeletal system diseaseDOID:172230.022
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
neurodegenerative diseaseDOID:12891020.016
cardiovascular system diseaseDOID:12871060.015
muscle tissue diseaseDOID:661130.015
myopathyDOID:4231040.015
muscular diseaseDOID:00800001140.015
cancerDOID:1621670.015
disease of cellular proliferationDOID:145661740.015
immune system diseaseDOID:29141550.014
retinal diseaseDOID:56791180.014
amino acid metabolic disorderDOID:9252500.014
organ system cancerDOID:00506861640.013
connective tissue diseaseDOID:651090.013
hematopoietic system diseaseDOID:741000.012
brain diseaseDOID:936730.011
retinal degenerationDOID:8466890.011
bone diseaseDOID:0080001880.011
epilepsy syndromeDOID:1826410.007
electroclinical syndromeDOID:0050701320.005
neonatal period electroclinical syndromeDOID:0050702190.003
ohtahara syndromeDOID:0050709170.003
idiopathic generalized epilepsyDOID:1827210.002
infantile epileptic encephalopathyDOID:2481120.002