Homo sapiens

119 known processes

MDM4

Mdm4 p53 binding protein homolog (mouse)

(Aliases: MDMX,MRP1,MGC132766,DKFZp781B1423,HDMX)

MDM4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugationGO:00324463421.000
Human
protein ubiquitinationGO:00165673140.993
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.988
regulation of peptidase activityGO:00525471800.984
apoptotic signaling pathwayGO:00971902680.981
intrinsic apoptotic signaling pathwayGO:00971931270.979
protein deubiquitinationGO:0016579790.969
positive regulation of proteasomal protein catabolic processGO:1901800350.965
Human
cellular response to dna damage stimulusGO:00069743790.960
regulation of proteolysisGO:00301622930.921
Human
cellular response to endogenous stimulusGO:00714953360.918
modification dependent macromolecule catabolic processGO:00436322120.914
Human
regulation of cell cycleGO:00517263930.908
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.900
Human
modification dependent protein catabolic processGO:00199412090.899
Human
protein polyubiquitinationGO:00002091100.888
apoptotic mitochondrial changesGO:0008637570.881
cellular protein catabolic processGO:00442572610.880
Human
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.875
Human
positive regulation of cellular catabolic processGO:00313312840.874
Human
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.874
positive regulation of proteolysisGO:00458621420.863
Human
proteasomal protein catabolic processGO:00104981760.852
Human
positive regulation of apoptotic processGO:00430652460.849
positive regulation of developmental processGO:00510943140.841
negative regulation of apoptotic processGO:00430663160.841
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.827
regulation of cellular component biogenesisGO:00440872810.827
regulation of apoptotic signaling pathwayGO:20012331750.815
ubiquitin dependent protein catabolic processGO:00065112060.796
Human
dna repairGO:00062811980.774
regulation of endopeptidase activityGO:00525481700.763
negative regulation of cell deathGO:00605483450.753
chromosome segregationGO:00070591140.746
negative regulation of programmed cell deathGO:00430693210.742
cellular macromolecule catabolic processGO:00442653800.734
Human
positive regulation of programmed cell deathGO:00430682490.718
positive regulation of cell deathGO:00109422630.698
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063330.696
cell developmentGO:00484683280.692
small gtpase mediated signal transductionGO:0007264780.681
cellular component morphogenesisGO:00329893140.678
regulation of mitotic cell cycleGO:00073461890.671
Human
regulation of cellular protein catabolic processGO:1903362960.662
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.658
Human
positive regulation of cysteine type endopeptidase activityGO:2001056790.641
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.641
positive regulation of catabolic processGO:00098963100.640
Human
regulation of cysteine type endopeptidase activityGO:20001161270.639
protein catabolic processGO:00301633250.627
protein modification by small protein removalGO:0070646920.623
regulation of protein stabilityGO:0031647870.607
regulation of sequence specific dna binding transcription factor activityGO:00510902110.600
protein processingGO:00164852260.589
negative regulation of cell cycleGO:00457861930.570
Human
mitotic cell cycle phase transitionGO:00447721620.567
Human
regulation of proteasomal protein catabolic processGO:0061136870.563
Human
activation of cysteine type endopeptidase activityGO:0097202570.557
regulation of wnt signaling pathwayGO:00301111230.543
release of cytochrome c from mitochondriaGO:0001836350.540
mitotic dna damage checkpointGO:0044773280.534
Human
mitotic dna integrity checkpointGO:0044774300.527
Human
regulation of growthGO:00400081650.524
taxisGO:00423301570.515
response to other organismGO:00517072610.509
protein autophosphorylationGO:00467771230.508
regulation of cell developmentGO:00602841610.500
regulation of cell morphogenesisGO:00226041530.497
chromatin modificationGO:00165682980.495
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.494
regulation of cell cycle processGO:00105642660.494
Human
response to abiotic stimulusGO:00096283360.492
regulation of nucleoside metabolic processGO:00091182090.470
positive regulation of hydrolase activityGO:00513453310.469
protein localization to organelleGO:00333652800.467
Human
positive regulation of cell cycle arrestGO:0071158230.460
Human
immune responseGO:00069553070.447
negative regulation of cellular component organizationGO:00511292350.446
positive regulation of cellular protein catabolic processGO:1903364370.443
Human
histone deubiquitinationGO:0016578160.443
post embryonic developmentGO:000979120.441
guanosine containing compound catabolic processGO:19010692390.425
response to bacteriumGO:00096171440.419
maintenance of locationGO:00512351120.417
negative regulation of protein modification processGO:00314002000.416
negative regulation of apoptotic signaling pathwayGO:2001234970.412
peptidyl threonine phosphorylationGO:0018107410.405
oocyte differentiationGO:000999420.396
negative regulation of cell proliferationGO:00082852280.396
defense responseGO:00069523150.391
cellular response to lipidGO:00713961270.388
peptidyl lysine modificationGO:00182051440.384
Human
regulation of signal transduction by p53 class mediatorGO:1901796260.377
Human
positive regulation of endopeptidase activityGO:0010950840.374
negative regulation of protein metabolic processGO:00512483910.367
regulation of hormone levelsGO:00108171250.366
ribonucleoside triphosphate catabolic processGO:00092033910.363
mitochondrion organizationGO:00070051560.363
ras protein signal transductionGO:0007265730.354
cellular macromolecular complex assemblyGO:00346223240.353
purine nucleoside triphosphate catabolic processGO:00091463920.350
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.348
organelle fissionGO:00482851490.341
organophosphate catabolic processGO:00464344300.337
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.336
Human
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.330
negative regulation of cellular protein metabolic processGO:00322693530.330
vesicle mediated transportGO:00161923710.330
cellular response to growth factor stimulusGO:00713631970.323
chromatin organizationGO:00063253510.322
regulation of response to external stimulusGO:00321012220.316
regulation of innate immune responseGO:0045088970.313
dna damage response signal transduction by p53 class mediatorGO:0030330440.313
regulation of purine nucleotide metabolic processGO:19005422640.313
response to caffeineGO:003100030.309
positive regulation of protein phosphorylationGO:00019343130.296
mitotic cell cycle processGO:19030472860.295
Human
regulation of cell divisionGO:00513021160.293
negative regulation of cell cycle processGO:00109481210.293
Human
positive regulation of cell differentiationGO:00455972110.289
regulation of cellular ketone metabolic processGO:0010565500.276
positive regulation of peptidase activityGO:0010952880.276
positive regulation of cellular component organizationGO:00511303760.274
response to organic cyclic compoundGO:00140702040.270
ameboidal type cell migrationGO:00016671350.268
response to biotic stimulusGO:00096072760.266
response to cytokineGO:00340972320.265
histone modificationGO:00165702510.259
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.257
Human
smoothened signaling pathwayGO:0007224140.255
cytoplasmic transportGO:00164823790.254
nucleoside triphosphate metabolic processGO:00091414220.251
microtubule cytoskeleton organizationGO:00002261760.245
protein deacylationGO:0035601390.242
regulation of response to dna damage stimulusGO:2001020940.242
Human
posttranscriptional regulation of gene expressionGO:00106082130.242
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.240
Human
cellular amino acid metabolic processGO:00065201160.239
response to external biotic stimulusGO:00432072610.239
negative regulation of mitotic cell cycleGO:00459301020.238
Human
guanosine containing compound metabolic processGO:19010682440.237
cell morphogenesis involved in differentiationGO:00009041440.235
purine ribonucleoside triphosphate metabolic processGO:00092054110.233
regulation of protein localizationGO:00328802960.232
response to radiationGO:00093141510.230
positive regulation of apoptotic signaling pathwayGO:2001235700.227
positive regulation of nucleotide metabolic processGO:00459812300.227
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.226
regulation of dna metabolic processGO:00510521530.226
positive regulation of canonical wnt signaling pathwayGO:0090263330.225
cellular response to hypoxiaGO:0071456510.224
intracellular receptor signaling pathwayGO:00305221040.223
purine nucleoside triphosphate metabolic processGO:00091444120.221
purine ribonucleoside metabolic processGO:00461284370.218
meiosis iGO:000712740.217
gtp metabolic processGO:00460392390.214
single organism cellular localizationGO:19025803320.211
limbic system developmentGO:002176130.210
developmental programmed cell deathGO:001062330.210
regulation of cellular response to stressGO:00801352440.208
Human
regulation of gtp catabolic processGO:00331241800.208
rna processingGO:00063962550.208
positive regulation of transportGO:00510503360.206
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.205
regulation of canonical wnt signaling pathwayGO:0060828880.205
multicellular organismal agingGO:001025930.203
regulation of locomotionGO:00400123290.203
positive regulation of ras gtpase activityGO:00323201170.201
negative regulation of proteolysisGO:00458611320.200
mitotic cytokinesisGO:0000281190.197
urogenital system developmentGO:0001655650.197
i kappab kinase nf kappab signalingGO:00072491660.196
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.194
positive regulation of cell cycleGO:00457871400.192
Human
regulation of cell morphogenesis involved in differentiationGO:0010769830.192
regulation of intracellular transportGO:00323861950.192
cellular response to cytokine stimulusGO:00713451810.191
positive regulation of protein catabolic processGO:0045732750.187
Human
purine containing compound catabolic processGO:00725234110.187
positive regulation of wnt signaling pathwayGO:0030177540.184
regulation of neuron differentiationGO:0045664700.182
cell cycle phase transitionGO:00447701730.177
Human
dna integrity checkpointGO:0031570710.175
Human
chemotaxisGO:00069351570.175
protein maturationGO:00516042330.175
cell cycle checkpointGO:00000751170.172
Human
negative regulation of smoothened signaling pathwayGO:004587930.170
response to tumor necrosis factorGO:0034612760.169
regulation of dna repairGO:0006282470.166
protein stabilizationGO:0050821640.165
protein oligomerizationGO:00512591730.160
regulation of protein modification by small protein conjugation or removalGO:19033201070.159
cellular response to oxygen containing compoundGO:19017012760.158
regulation of cytoskeleton organizationGO:00514931770.156
maintenance of location in cellGO:0051651620.155
ribonucleotide catabolic processGO:00092614050.155
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193020.155
cellular amine metabolic processGO:0044106410.151
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.150
regulation of microtubule based processGO:0032886740.150
protein k48 linked deubiquitinationGO:0071108190.149
regulation of mitochondrion organizationGO:0010821540.149
regulation of protein targetingGO:1903533910.147
regulation of cellular amine metabolic processGO:0033238110.147
mitotic cell cycle checkpointGO:0007093680.146
Human
response to growth factorGO:00708482050.146
regulation of ion transportGO:00432691890.146
growthGO:00400072020.146
oogenesisGO:004847720.145
positive regulation of purine nucleotide catabolic processGO:00331231850.144
regulation of protein processingGO:00706131500.144
defense response to other organismGO:00985421290.144
purine ribonucleoside triphosphate catabolic processGO:00092073910.143
cell divisionGO:00513011680.143
cell projection morphogenesisGO:00488581290.142
g1 s transition of mitotic cell cycleGO:0000082780.141
Human
intracellular protein transportGO:00068862700.139
trna modificationGO:0006400100.138
regulation of cytoplasmic transportGO:19036491490.137
meiotic chromosome segregationGO:004513240.135
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008380.132
negative regulation of hydrolase activityGO:00513461820.131
regulation of leukocyte proliferationGO:0070663670.130
glycosyl compound catabolic processGO:19016584130.128
regulation of protein complex assemblyGO:00432541470.127
microtubule based processGO:00070172100.127
positive regulation of nucleoside metabolic processGO:00459791860.126
female gamete generationGO:000729220.126
regulation of nucleotide catabolic processGO:00308112050.125
ribonucleoside triphosphate metabolic processGO:00091994120.125
amine metabolic processGO:0009308440.124
negative regulation of nf kappab transcription factor activityGO:0032088510.123
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.123
gtp catabolic processGO:00061842370.123
mitotic centrosome separationGO:000710010.123
trna wobble uridine modificationGO:000209830.123
zymogen activationGO:0031638700.122
dna damage induced protein phosphorylationGO:000697550.122
regulation of defense responseGO:00313471540.122
viral processGO:00160321460.122
hematopoietic or lymphoid organ developmentGO:00485341860.121
cellular ketone metabolic processGO:0042180800.121
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.121
oxidation reduction processGO:00551143960.120
response to ionizing radiationGO:0010212650.120
positive regulation of defense responseGO:0031349870.119
negative regulation of dna replicationGO:0008156290.116
positive regulation of organelle organizationGO:00106381950.116
response to oxygen containing compoundGO:19017003690.115
response to decreased oxygen levelsGO:0036293960.114
regulation of protein catabolic processGO:00421761550.114
negative regulation of protein maturationGO:19033181420.113
regulation of microtubule cytoskeleton organizationGO:0070507610.113
membrane organizationGO:00610242920.112
rho protein signal transductionGO:0007266260.112
mitotic cell cycleGO:00002783260.111
Human
regulation of cellular component movementGO:00512703340.109
positive regulation of cell proliferationGO:00082843010.108
Mouse
negative regulation of protein processingGO:00109551420.108
glucan metabolic processGO:0044042220.107
protein autoubiquitinationGO:0051865370.106
positive regulation of phosphorylationGO:00423273940.106
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.106
regulation of histone modificationGO:0031056470.105
determination of adult lifespanGO:000834020.105
negative regulation of multicellular organismal processGO:00512413170.104
cellular response to abiotic stimulusGO:00712141170.103
cellular response to ionizing radiationGO:0071479320.103
response to nitrogen compoundGO:19016981840.102
positive regulation of epithelial cell proliferationGO:0050679650.102
histone acetylationGO:0016573930.101
negative regulation of myotube differentiationGO:001083240.101
maintenance of protein location in cellGO:0032507560.101
negative regulation of organelle organizationGO:00106391260.100
cellular response to organic cyclic compoundGO:00714071270.099
nucleus organizationGO:0006997280.099
peptidyl lysine acetylationGO:00183941010.099
cellular homeostasisGO:00197251960.098
cellular chemical homeostasisGO:00550821800.098
ribosome biogenesisGO:0042254480.097
regulation of protein maturationGO:19033171500.097
anterior posterior axis specificationGO:000994820.096
actin filament based processGO:00300292240.096
establishment of organelle localizationGO:0051656590.095
negative regulation of multi organism processGO:0043901920.095
regulation of multi organism processGO:00439001570.095
developmental process involved in reproductionGO:0003006660.094
substrate adhesion dependent cell spreadingGO:0034446410.094
regulation of epithelial cell proliferationGO:00506781130.093
purine nucleoside catabolic processGO:00061523980.093
cell adhesionGO:00071553250.092
canonical wnt signaling pathwayGO:00600701160.092
protein acetylationGO:00064731160.090
ncrna processingGO:0034470830.090
positive regulation of nuclease activityGO:003207550.090
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.089
nucleotide catabolic processGO:00091664080.088
peptidyl serine phosphorylationGO:00181051010.087
interleukin 1 productionGO:0032612260.086
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.086
negative regulation of cell cycle phase transitionGO:1901988890.085
Human
response to organonitrogen compoundGO:00102431560.084
response to metal ionGO:0010038840.084
maintenance of protein locationGO:0045185570.084
negative regulation of cell cycle g1 s phase transitionGO:1902807290.084
Human
negative regulation of cysteine type endopeptidase activityGO:2000117480.083
histone threonine phosphorylationGO:003540570.083
bmp signaling pathwayGO:0030509490.082
positive regulation of apoptotic process involved in mammary gland involutionGO:006005810.082
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.080
nucleoside catabolic processGO:00091644080.080
regulation of protein kinase activityGO:00458592890.079
regulation of secretion by cellGO:19035301770.079
regulation of dna templated transcription in response to stressGO:0043620180.079
cytokine productionGO:00018162470.079
regulation of transferase activityGO:00513383550.078
neuron differentiationGO:00301821380.077
cell morphogenesisGO:00009022960.077
regulation of chromatin modificationGO:1903308510.076
positive regulation of cellular amino acid metabolic processGO:004576430.076
nuclear transportGO:00511691790.075
oxidative stress induced premature senescenceGO:009040330.075
regulation of protein transportGO:00512232130.074
regulation of purine nucleotide catabolic processGO:00331212050.074
response to lipidGO:00339932060.074
establishment or maintenance of cytoskeleton polarityGO:003095230.074
immune system developmentGO:00025201950.073
ribonucleoside monophosphate metabolic processGO:00091611870.073
regulation of cell differentiationGO:00455953930.072
ribonucleoside catabolic processGO:00424544060.072
regulation of protein ubiquitinationGO:0031396950.072
positive regulation of endothelial cell proliferationGO:0001938370.072
response to gamma radiationGO:0010332140.072
dna damage checkpointGO:0000077680.072
Human
single organism membrane organizationGO:00448022680.070
positive regulation of apoptotic process involved in morphogenesisGO:190233910.070
regulation of anatomical structure morphogenesisGO:00226032860.070
histone h2a ubiquitinationGO:0033522170.070
negative regulation of transferase activityGO:00513481240.070
protein k63 linked ubiquitinationGO:0070534310.070
male meiosisGO:000714010.070
negative regulation of immune responseGO:0050777400.069
er to golgi vesicle mediated transportGO:0006888190.069
oocyte developmentGO:004859910.068
cellular response to radiationGO:0071478650.068
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.068
regulation of ras protein signal transductionGO:00465781550.068
regulation of gtpase activityGO:00430871800.067
spindle assemblyGO:0051225290.067
interleukin 2 productionGO:0032623200.067
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.066
androgen receptor signaling pathwayGO:0030521340.065
nucleoside triphosphate catabolic processGO:00091433940.065
substantia nigra developmentGO:0021762450.065
endosomal transportGO:00161971290.064
transforming growth factor beta receptor signaling pathwayGO:0007179760.064
cell substrate adhesionGO:00315891320.064
positive regulation of growthGO:0045927580.063
negative regulation of catalytic activityGO:00430863350.063
ribonucleoprotein complex biogenesisGO:00226131160.062
regulation of defense response to bacteriumGO:190042420.062
erk1 and erk2 cascadeGO:00703711040.061
positive regulation of nucleotide catabolic processGO:00308131850.061
intracellular steroid hormone receptor signaling pathwayGO:0030518610.061
negative regulation of kinase activityGO:00336731060.061
cell chemotaxisGO:00603261120.059
purine nucleoside monophosphate metabolic processGO:00091261860.058
positive regulation of erythrocyte differentiationGO:0045648110.058
lipid metabolic processGO:00066293810.058
specification of organ identityGO:001009230.058
nuclear divisionGO:00002801280.057
regulation of cell cycle phase transitionGO:19019871260.057
Human
regulation of carbohydrate metabolic processGO:0006109540.057
hematopoietic progenitor cell differentiationGO:0002244380.057
negative regulation of defense responseGO:0031348470.057
negative regulation of protein phosphorylationGO:00019331400.057
mitochondrial transportGO:0006839600.057
tissue migrationGO:00901301190.057
positive regulation of dendrite morphogenesisGO:005077530.056
angiogenesisGO:00015251470.056
activation of innate immune responseGO:0002218550.056
cellular response to organonitrogen compoundGO:00714171240.055
positive regulation of cellular component biogenesisGO:00440891580.055
protein targetingGO:00066051870.055
regulation of homeostatic processGO:00328441210.055
hormone transportGO:0009914680.054
negative regulation of peptidase activityGO:0010466910.054
signal transduction by p53 class mediatorGO:0072331720.053
male gonad developmentGO:0008584230.053
cellular component disassemblyGO:0022411920.053
regulation of cell growthGO:00015581350.052
ribonucleoside monophosphate catabolic processGO:00091581580.052
regulation of i kappab kinase nf kappab signalingGO:00431221620.052
organ morphogenesisGO:00098871470.052
mitotic sister chromatid segregationGO:0000070530.052
vasculature developmentGO:00019441810.051
regulation of release of cytochrome c from mitochondriaGO:0090199290.051
energy reserve metabolic processGO:0006112220.051
negative regulation of protein kinase activityGO:0006469980.051
pattern specification processGO:0007389430.051
regulation of transcription from rna polymerase ii promoter in response to stressGO:0043618170.051
cellular response to tumor necrosis factorGO:0071356630.051
golgi vesicle transportGO:0048193800.051
extrinsic apoptotic signaling pathwayGO:00971911190.051
myeloid cell differentiationGO:00300991170.050
regulation of cell motilityGO:20001452990.050
meiotic nuclear divisionGO:0007126100.050
morphogenesis of a branching epitheliumGO:0061138200.050
phosphatidylinositol 3 kinase signalingGO:0014065480.050
wnt signaling pathwayGO:00160551560.050
ncrna metabolic processGO:00346601080.049
internal protein amino acid acetylationGO:00064751010.049
organelle assemblyGO:00709251760.049
regulation of dendrite morphogenesisGO:0048814110.048
regulation of generation of precursor metabolites and energyGO:0043467270.048
enzyme linked receptor protein signaling pathwayGO:00071673030.047
negative regulation of intracellular signal transductionGO:19025321830.047
Human
regulation of bindingGO:00510981110.047
single organismal cell cell adhesionGO:00163371480.047
positive regulation of response to interferon gammaGO:006033220.047
cytokine mediated signaling pathwayGO:00192211090.047
regulation of mitotic cell cycle phase transitionGO:19019901180.046
Human
negative regulation of locomotionGO:00400131180.046
negative regulation of protein serine threonine kinase activityGO:0071901570.046
dna replicationGO:00062601160.046
regulation of actin cytoskeleton organizationGO:00329561160.046
endomembrane system organizationGO:00102561960.046
autophagyGO:0006914880.046
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697790.046
Human
regulation of immune responseGO:00507762010.045
regulation of cytokinesisGO:0032465450.045
negative regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:001705520.045
nervous system developmentGO:00073992930.045
negative regulation of endothelial cell apoptotic processGO:2000352160.045
female sex differentiationGO:0046660120.045
cellular response to nitrogen compoundGO:19016991440.044
histone h3 acetylationGO:0043966450.044
actin filament organizationGO:00070151280.043
vesicle organizationGO:0016050620.043
macromolecule deacylationGO:0098732410.043
protein targeting to nucleusGO:00447441040.043
cellular response to purine containing compoundGO:007141530.043
response to purine containing compoundGO:0014074400.043
trna processingGO:0008033230.042
cell part morphogenesisGO:00329901370.042
epithelial cell proliferationGO:00506731280.042
nucleoside phosphate catabolic processGO:19012924120.042
single organism nuclear importGO:19025931040.042
histone deacetylationGO:0016575320.041
positive regulation of interferon gamma mediated signaling pathwayGO:006033520.041
cellular response to decreased oxygen levelsGO:0036294510.041
reactive oxygen species biosynthetic processGO:190340940.041
apoptotic process involved in morphogenesisGO:006056130.041
positive regulation of innate immune responseGO:0045089790.041
cellular metal ion homeostasisGO:00068751460.040
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.040
regulation of ras gtpase activityGO:00323181280.040
transcription initiation from rna polymerase ii promoterGO:0006367270.040
retina layer formationGO:001084230.040
protein acylationGO:00435431380.040
ribosomal large subunit biogenesisGO:0042273100.040
response to alkaloidGO:0043279200.040
purine nucleotide catabolic processGO:00061954050.039
regulation of cell migrationGO:00303342890.039
cellular response to biotic stimulusGO:0071216710.039
peptidyl serine dephosphorylationGO:007026220.039
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.039
glucocorticoid catabolic processGO:000671310.039
calcium ion transportGO:00068161470.039
peptidyl threonine modificationGO:0018210450.038
regenerationGO:003109940.038
potassium ion transmembrane transportGO:0071805600.038
negative regulation of innate immune responseGO:0045824180.038
cellular calcium ion homeostasisGO:00068741170.038
organelle localizationGO:0051640840.038
leukocyte chemotaxisGO:0030595760.038
intra s dna damage checkpointGO:003157340.037
cellular response to caffeineGO:007131330.037
cytokinesisGO:0000910960.037
prostate gland developmentGO:003085030.037
cell cycle arrestGO:0007050710.037
Human
patterning of blood vesselsGO:000156920.037
immune response activating signal transductionGO:0002757900.037
positive regulation of cell divisionGO:0051781590.037
multi organism cellular processGO:00447641560.036
establishment or maintenance of bipolar cell polarityGO:006124520.036
positive regulation of leukocyte migrationGO:0002687460.036
regulation of glycogen biosynthetic processGO:0005979140.035
positive regulation of mitochondrion organizationGO:0010822300.035
tube developmentGO:00352951250.035

MDM4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.193
disease of cellular proliferationDOID:145661740.193
organ system cancerDOID:00506861640.193
musculoskeletal system cancerDOID:0060100110.088
connective tissue cancerDOID:20170.088