Homo sapiens

32 known processes

LGMN

legumain

(Aliases: PRSC1,AEP,LGMN1)

LGMN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.092
immune responseGO:00069553070.068
chemical homeostasisGO:00488783060.063
cellular amino acid metabolic processGO:00065201160.062
regulation of cellular amino acid metabolic processGO:000652160.061
determination of adult lifespanGO:000834020.060
cellular ketone metabolic processGO:0042180800.053
cellular amine metabolic processGO:0044106410.053
amine metabolic processGO:0009308440.048
signal transduction by phosphorylationGO:00230142970.046
regulation of cytokine productionGO:00018172320.045
regulation of cellular amine metabolic processGO:0033238110.045
response to oxygen containing compoundGO:19017003690.044
positive regulation of cellular amine metabolic processGO:003324070.042
cellular macromolecule catabolic processGO:00442653800.042
Mouse
glycosyl compound catabolic processGO:19016584130.042
purine containing compound catabolic processGO:00725234110.042
response to cytokineGO:00340972320.040
transmembrane transportGO:00550853990.039
organophosphate catabolic processGO:00464344300.037
cellular response to endogenous stimulusGO:00714953360.036
purine ribonucleoside metabolic processGO:00461284370.036
proteolysis involved in cellular protein catabolic processGO:00516032440.036
Mouse
response to abiotic stimulusGO:00096283360.036
Mouse
nucleoside triphosphate metabolic processGO:00091414220.035
nucleoside catabolic processGO:00091644080.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
ras protein signal transductionGO:0007265730.035
purine ribonucleoside catabolic processGO:00461303980.035
protein catabolic processGO:00301633250.035
Mouse
regulation of cellular ketone metabolic processGO:0010565500.035
positive regulation of phosphorylationGO:00423273940.035
negative regulation of catalytic activityGO:00430863350.034
positive regulation of cellular component organizationGO:00511303760.033
defense responseGO:00069523150.033
response to biotic stimulusGO:00096072760.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
lipid metabolic processGO:00066293810.032
multicellular organismal agingGO:001025930.032
regulation of transferase activityGO:00513383550.031
ribonucleotide catabolic processGO:00092614050.031
cellular response to oxygen containing compoundGO:19017012760.031
nucleoside triphosphate catabolic processGO:00091433940.031
locomotory behaviorGO:000762610.031
nucleotide catabolic processGO:00091664080.031
protein maturationGO:00516042330.031
ion transmembrane transportGO:00342203380.031
regulation of response to external stimulusGO:00321012220.031
negative regulation of cellular protein metabolic processGO:00322693530.030
negative regulation of multicellular organismal processGO:00512413170.030
Mouse
nucleoside phosphate catabolic processGO:19012924120.030
negative regulation of cell deathGO:00605483450.030
positive regulation of catabolic processGO:00098963100.030
vesicle mediated transportGO:00161923710.029
ribonucleoside catabolic processGO:00424544060.029
regulation of protein localizationGO:00328802960.029
cytoplasmic transportGO:00164823790.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of hydrolase activityGO:00513453310.029
mapk cascadeGO:00001652880.029
ion homeostasisGO:00508012300.029
negative regulation of programmed cell deathGO:00430693210.029
cell adhesionGO:00071553250.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
purine ribonucleotide catabolic processGO:00091544040.029
purine nucleoside triphosphate metabolic processGO:00091444120.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
positive regulation of immune system processGO:00026842830.028
inorganic ion transmembrane transportGO:00986602310.028
negative regulation of phosphorus metabolic processGO:00105632670.028
purine nucleoside catabolic processGO:00061523980.028
positive regulation of cellular catabolic processGO:00313312840.027
single organism carbohydrate metabolic processGO:00447231930.027
purine nucleotide catabolic processGO:00061954050.027
carbohydrate metabolic processGO:00059752070.027
single organism cellular localizationGO:19025803320.027
cellular protein catabolic processGO:00442572610.026
Mouse
innate immune responseGO:00450871780.026
regulation of cellular response to stressGO:00801352440.026
cellular homeostasisGO:00197251960.026
apoptotic signaling pathwayGO:00971902680.026
cytokine productionGO:00018162470.026
response to bacteriumGO:00096171440.026
response to oxidative stressGO:00069791210.026
cellular lipid metabolic processGO:00442553030.026
rho protein signal transductionGO:0007266260.026
regulation of mapk cascadeGO:00434082620.025
response to woundingGO:00096111680.025
cellular chemical homeostasisGO:00550821800.025
system processGO:00030083490.025
Mouse
regulation of establishment of protein localizationGO:00702012420.025
protein processingGO:00164852260.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
regenerationGO:003109940.025
cation homeostasisGO:00550801890.024
response to nitrogen compoundGO:19016981840.024
female gamete generationGO:000729220.024
regulation of cell migrationGO:00303342890.024
small gtpase mediated signal transductionGO:0007264780.024
regulation of anatomical structure morphogenesisGO:00226032860.024
secretionGO:00469032540.024
response to thyroid hormoneGO:009706690.023
intracellular protein transportGO:00068862700.023
biological adhesionGO:00226103310.023
regulation of nucleotide metabolic processGO:00061402690.023
response to hormoneGO:00097251750.023
response to organic cyclic compoundGO:00140702040.023
response to growth factorGO:00708482050.023
metal ion homeostasisGO:00550651690.023
cellular macromolecular complex assemblyGO:00346223240.023
negative regulation of locomotionGO:00400131180.022
single organismal cell cell adhesionGO:00163371480.022
positive regulation of transportGO:00510503360.022
cell morphogenesisGO:00009022960.022
regulation of kinase activityGO:00435493140.022
cellular component morphogenesisGO:00329893140.022
regulation of cell differentiationGO:00455953930.022
gtp metabolic processGO:00460392390.021
neurological system processGO:00508771630.021
negative regulation of hydrolase activityGO:00513461820.021
membrane organizationGO:00610242920.021
regulation of locomotionGO:00400123290.021
regulation of purine nucleotide metabolic processGO:19005422640.021
regulation of cellular component movementGO:00512703340.021
segmentationGO:003528240.021
response to other organismGO:00517072610.021
regulation of protein transportGO:00512232130.021
glial cell migrationGO:000834740.021
regulation of purine nucleotide catabolic processGO:00331212050.021
positive regulation of transferase activityGO:00513472270.021
cation transportGO:00068123310.020
regulation of cell motilityGO:20001452990.020
single organism membrane organizationGO:00448022680.020
negative regulation of phosphate metabolic processGO:00459362670.020
cellular cation homeostasisGO:00300031630.020
regulation of protein kinase activityGO:00458592890.020
regulation of response to woundingGO:19030341010.020
oxidation reduction processGO:00551143960.020
positive regulation of cell motilityGO:20001471770.020
gtp catabolic processGO:00061842370.020
protein oligomerizationGO:00512591730.020
regulation of intracellular transportGO:00323861950.020
response to inorganic substanceGO:00100351270.020
positive regulation of nucleoside metabolic processGO:00459791860.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
cellular ion homeostasisGO:00068731680.019
regulation of proteolysisGO:00301622930.019
oogenesisGO:004847720.019
endomembrane system organizationGO:00102561960.019
carbohydrate derivative biosynthetic processGO:19011372070.019
divalent inorganic cation homeostasisGO:00725071360.019
positive regulation of cytokine productionGO:00018191670.019
actin filament based processGO:00300292240.019
positive regulation of programmed cell deathGO:00430682490.019
cell projection organizationGO:00300302520.019
cellular metal ion homeostasisGO:00068751460.019
cellular response to growth factor stimulusGO:00713631970.019
positive regulation of apoptotic processGO:00430652460.019
reactive oxygen species metabolic processGO:0072593750.019
protein modification by small protein conjugationGO:00324463420.019
dephosphorylationGO:00163112090.019
positive regulation of cell proliferationGO:00082843010.019
negative regulation of developmental processGO:00510932470.019
Mouse
positive regulation of cell deathGO:00109422630.018
cation transmembrane transportGO:00986552380.018
guanosine containing compound catabolic processGO:19010692390.018
guanosine containing compound metabolic processGO:19010682440.018
cellular response to cytokine stimulusGO:00713451810.018
epithelial cell proliferationGO:00506731280.018
regulation of protein processingGO:00706131500.018
regulation of secretionGO:00510461940.018
sulfur compound metabolic processGO:00067901010.018
basement membrane organizationGO:007171130.018
memoryGO:000761330.017
growthGO:00400072020.017
Mouse
peptidyl tyrosine modificationGO:00182121700.017
circulatory system developmentGO:00723592620.017
positive regulation of nucleotide catabolic processGO:00308131850.017
immune system developmentGO:00025201950.017
cellular protein complex assemblyGO:00436231880.017
regulation of cellular component biogenesisGO:00440872810.017
response to external biotic stimulusGO:00432072610.017
positive regulation of protein phosphorylationGO:00019343130.017
positive regulation of kinase activityGO:00336742040.017
glycoprotein metabolic processGO:00091001100.017
reactive oxygen species biosynthetic processGO:190340940.017
negative regulation of cell motilityGO:20001461040.017
regulation of defense responseGO:00313471540.017
negative regulation of cellular component organizationGO:00511292350.016
regulation of cell adhesionGO:00301551660.016
neuromuscular junction developmentGO:000752830.016
small molecule biosynthetic processGO:00442831570.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
maintenance of locationGO:00512351120.016
negative regulation of apoptotic processGO:00430663160.016
negative regulation of response to external stimulusGO:0032102830.016
regulation of peptidase activityGO:00525471800.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
Mouse
positive regulation of mapk cascadeGO:00434101900.016
collagen metabolic processGO:0032963280.016
regulation of gtp catabolic processGO:00331241800.016
sensory perception of painGO:001923340.016
regulation of protein catabolic processGO:00421761550.016
wound healingGO:00420601150.016
inner ear morphogenesisGO:004247240.016
regulation of secretion by cellGO:19035301770.016
positive regulation of secretionGO:00510471160.016
response to axon injuryGO:004867810.016
positive regulation of gtpase activityGO:00435471660.016
organonitrogen compound biosynthetic processGO:19015662000.016
protein localization to organelleGO:00333652800.016
multicellular organismal metabolic processGO:0044236340.016
inorganic cation transmembrane transportGO:00986621940.016
cellular response to dna damage stimulusGO:00069743790.016
tissue regenerationGO:004224630.015
response to reactive oxygen speciesGO:0000302610.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
regulation of endopeptidase activityGO:00525481700.015
adult locomotory behaviorGO:000834410.015
regulation of nucleotide catabolic processGO:00308112050.015
negative regulation of proteolysisGO:00458611320.015
cardiovascular system developmentGO:00723582620.015
cellular response to hormone stimulusGO:00328701250.015
regulation of cytoskeleton organizationGO:00514931770.015
negative regulation of protein processingGO:00109551420.015
regulation of nucleoside metabolic processGO:00091182090.015
negative regulation of protein maturationGO:19033181420.015
positive regulation of organelle organizationGO:00106381950.015
epithelium developmentGO:00604292270.015
posttranscriptional regulation of gene expressionGO:00106082130.015
cell developmentGO:00484683280.015
lipid biosynthetic processGO:00086101770.015
negative regulation of cell migrationGO:00303361020.015
nervous system developmentGO:00073992930.014
cellular response to glucocorticoid stimulusGO:007138540.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of gtpase activityGO:00430871800.014
regulation of immune responseGO:00507762010.014
regulation of cytoplasmic transportGO:19036491490.014
g protein coupled receptor signaling pathwayGO:00071862070.014
hemopoiesisGO:00300971800.014
modification dependent protein catabolic processGO:00199412090.014
cellular response to oxidative stressGO:0034599850.014
negative regulation of intracellular signal transductionGO:19025321830.014
positive regulation of locomotionGO:00400171860.014
vasculature developmentGO:00019441810.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
negative regulation of immune system processGO:00026831360.014
blood vessel morphogenesisGO:00485141620.014
neurogenesisGO:00220081690.014
secretion by cellGO:00329402260.014
positive regulation of developmental processGO:00510943140.014
anion transportGO:00068201610.014
response to organonitrogen compoundGO:00102431560.014
negative regulation of protein modification processGO:00314002000.014
cellular response to organic cyclic compoundGO:00714071270.014
negative regulation of cellular amine metabolic processGO:003323930.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
response to lipidGO:00339932060.014
protein localization to membraneGO:00726571600.014
regulation of intracellular protein transportGO:00331571230.014
organic anion transportGO:00157111030.014
regulation of macrophage chemotaxisGO:001075840.014
mitotic cell cycleGO:00002783260.014
negative regulation of peptidase activityGO:0010466910.014
positive regulation of cellular component movementGO:00512721810.014
cellular response to external stimulusGO:00714961110.014
ubiquitin dependent protein catabolic processGO:00065112060.014
positive regulation of protein kinase activityGO:00458601900.014
modification dependent macromolecule catabolic processGO:00436322120.013
cellular response to thyroid hormone stimulusGO:009706790.013
regulation of ras protein signal transductionGO:00465781550.013
positive regulation of cell differentiationGO:00455972110.013
cellular component disassemblyGO:0022411920.013
regulation of cellular response to growth factor stimulusGO:0090287760.013
regulation of epithelial cell proliferationGO:00506781130.013
positive regulation of nucleotide metabolic processGO:00459812300.013
syncytium formation by plasma membrane fusionGO:000076820.013
proteasomal protein catabolic processGO:00104981760.013
rhythmic behaviorGO:000762220.013
peptidyl tyrosine phosphorylationGO:00181081700.013
protein homooligomerizationGO:00512601000.013
peripheral nervous system developmentGO:000742220.013
monocarboxylic acid metabolic processGO:00327871850.013
nerve developmentGO:002167540.013
nitrogen compound transportGO:00717051910.013
epithelial cell differentiationGO:00308551410.013
positive regulation of immune responseGO:00507781590.013
regulation of lipid metabolic processGO:0019216960.013
negative regulation of cell proliferationGO:00082852280.013
blastoderm segmentationGO:000735020.013
sequestering of metal ionGO:0051238240.013
establishment of planar polarityGO:000173630.012
positive regulation of protein transportGO:00512221350.012
regulation of cell cycleGO:00517263930.012
spermatid differentiationGO:004851540.012
regulation of actin filament based processGO:00329701410.012
anatomical structure homeostasisGO:00602491000.012
cell growthGO:00160491600.012
nuclear transportGO:00511691790.012
negative regulation of synaptic transmissionGO:005080520.012
protein ubiquitinationGO:00165673140.012
matingGO:000761810.012
response to tumor necrosis factorGO:0034612760.012
adaptive immune responseGO:0002250490.012
negative regulation of phosphorylationGO:00423261740.012
organic hydroxy compound metabolic processGO:19016151470.012
positive regulation of gtp catabolic processGO:00331261660.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
metal ion transportGO:00300012720.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
nucleocytoplasmic transportGO:00069131760.012
i kappab kinase nf kappab signalingGO:00072491660.012
regulation of cell morphogenesisGO:00226041530.012
regulation of ras gtpase activityGO:00323181280.012
regulation of bindingGO:00510981110.012
circulatory system processGO:00030131130.012
embryonic epithelial tube formationGO:000183840.012
regulation of apoptotic signaling pathwayGO:20012331750.012
associative learningGO:000830610.012
positive regulation of cell migrationGO:00303351720.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
Mouse
regulation of vasculature developmentGO:1901342970.012
positive regulation of synaptic transmissionGO:005080640.012
negative regulation of endopeptidase activityGO:0010951840.012
protein secretionGO:0009306980.012
single organism cell adhesionGO:00986021790.012
generation of neuronsGO:00486991520.012
regulation of homeostatic processGO:00328441210.012
organophosphate biosynthetic processGO:00904071630.012
endosomal transportGO:00161971290.012
regulation of protein maturationGO:19033171500.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
hemostasisGO:0007599760.012
negative regulation of protein phosphorylationGO:00019331400.012
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.012
myeloid cell differentiationGO:00300991170.012
negative regulation of blood pressureGO:004577630.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
actin cytoskeleton organizationGO:00300362070.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of synaptic plasticityGO:004816730.011
positive regulation of secretion by cellGO:19035321080.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
cell activationGO:00017752130.011
negative regulation of response to woundingGO:1903035470.011
response to fungusGO:000962040.011
organic acid biosynthetic processGO:0016053970.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
regulation of multi organism processGO:00439001570.011
positive regulation of proteolysisGO:00458621420.011
sensory perceptionGO:00076001030.011
blood vessel developmentGO:00015681720.011
circadian behaviorGO:004851220.011
hindbrain developmentGO:003090230.011
mitotic cell cycle processGO:19030472860.011
lipid transportGO:0006869900.011
reactive nitrogen species metabolic processGO:200105730.011
nucleoside monophosphate metabolic processGO:00091231910.011
morphogenesis of a polarized epitheliumGO:000173830.011
regulation of ion transportGO:00432691890.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
visual behaviorGO:000763220.011
autophagyGO:0006914880.011
angiogenesisGO:00015251470.011
regulation of hormone levelsGO:00108171250.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
neurotransmitter secretionGO:000726940.011
carboxylic acid biosynthetic processGO:0046394970.011
thymus developmentGO:004853830.011
regulation of actin cytoskeleton organizationGO:00329561160.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
activation of immune responseGO:00022531140.011
multicellular organismal macromolecule metabolic processGO:0044259290.011
coagulationGO:0050817780.011
positive regulation of macrophage chemotaxisGO:001075930.011
protein targetingGO:00066051870.011
negative regulation of cell differentiationGO:00455961710.011
positive regulation of ras gtpase activityGO:00323201170.011
negative regulation of t cell apoptotic processGO:007023340.011
regulation of protein bindingGO:0043393660.011
regulation of system processGO:00440571010.011
embryo developmentGO:00097901230.011
regulation of neural precursor cell proliferationGO:200017740.011
cellular response to abiotic stimulusGO:00712141170.011
spermatid developmentGO:000728640.011
glycoprotein biosynthetic processGO:0009101910.010
neural tube formationGO:000184130.010
regulation of cell cycle processGO:00105642660.010
oocyte developmentGO:004859910.010
regulation of vesicle mediated transportGO:00606271300.010
sodium ion transportGO:0006814610.010
regulation of stress activated mapk cascadeGO:0032872840.010
cellular response to lipidGO:00713961270.010
regulation of ion transmembrane transportGO:00347651320.010
atp metabolic processGO:00460341760.010
regulation of protein complex assemblyGO:00432541470.010
protein autophosphorylationGO:00467771230.010
nucleoside monophosphate catabolic processGO:00091251590.010
divalent inorganic cation transportGO:00725111580.010
multi organism cellular processGO:00447641560.010
response to nitric oxideGO:007173140.010
wnt signaling pathwayGO:00160551560.010
plasma membrane organizationGO:00070091150.010
microtubule based processGO:00070172100.010
cell cycle phase transitionGO:00447701730.010
primary neural tube formationGO:001402030.010
regulation of protein serine threonine kinase activityGO:00719001790.010
salivary gland morphogenesisGO:000743540.010
regulation of wnt signaling pathwayGO:00301111230.010
positive regulation of intracellular transportGO:00323881040.010
rna interferenceGO:001624640.010
negative regulation of cytokine productionGO:0001818820.010
establishment of protein localization to organelleGO:00725941720.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
phospholipid metabolic processGO:0006644990.010

LGMN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.078
inherited metabolic disorderDOID:6552420.069
lysosomal storage diseaseDOID:3211470.059
nervous system diseaseDOID:8634310.036
central nervous system diseaseDOID:3311860.036
sensory system diseaseDOID:00501552030.032
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.019
musculoskeletal system diseaseDOID:172230.019
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.016
retinal degenerationDOID:8466890.016
retinal diseaseDOID:56791180.016
lipid storage diseaseDOID:9455280.016
organ system cancerDOID:00506861640.014
immune system diseaseDOID:29141550.014
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.014
acquired metabolic diseaseDOID:0060158580.013
brain diseaseDOID:936730.011