Homo sapiens

143 known processes

EIF2B3

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

(Aliases: EIF2Bgamma,EIF-2B)

EIF2B3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oligodendrocyte developmentGO:001400360.990
translationGO:00064121320.321
positive regulation of nucleotide catabolic processGO:00308131850.304
regulation of nucleotide catabolic processGO:00308112050.303
posttranscriptional regulation of gene expressionGO:00106082130.301
Yeast Worm
positive regulation of nucleoside metabolic processGO:00459791860.295
guanosine containing compound catabolic processGO:19010692390.295
gtp catabolic processGO:00061842370.274
regulation of gtp catabolic processGO:00331241800.228
positive regulation of purine nucleotide catabolic processGO:00331231850.226
nucleoside triphosphate catabolic processGO:00091433940.226
gtp metabolic processGO:00460392390.211
positive regulation of nucleotide metabolic processGO:00459812300.208
guanosine containing compound metabolic processGO:19010682440.208
regulation of gtpase activityGO:00430871800.196
positive regulation of gtpase activityGO:00435471660.192
nucleoside catabolic processGO:00091644080.176
positive regulation of gtp catabolic processGO:00331261660.173
post embryonic developmentGO:000979120.168
Worm
positive regulation of cellular catabolic processGO:00313312840.164
regulation of purine nucleotide metabolic processGO:19005422640.164
nucleoside triphosphate metabolic processGO:00091414220.159
mitochondrial respiratory chain complex i biogenesisGO:0097031160.150
positive regulation of hydrolase activityGO:00513453310.146
protein processingGO:00164852260.138
system processGO:00030083490.137
purine nucleoside triphosphate metabolic processGO:00091444120.134
purine nucleotide catabolic processGO:00061954050.125
vesicle mediated transportGO:00161923710.116
Worm
nervous system developmentGO:00073992930.114
ribonucleoside triphosphate catabolic processGO:00092033910.109
protein maturationGO:00516042330.095
nucleic acid phosphodiester bond hydrolysisGO:00903051020.095
translational initiationGO:0006413480.092
response to hormoneGO:00097251750.089
nucleotide catabolic processGO:00091664080.086
response to nitrogen compoundGO:19016981840.085
cellular amino acid metabolic processGO:00065201160.083
purine nucleoside catabolic processGO:00061523980.079
regulation of membrane potentialGO:0042391950.079
nadh dehydrogenase complex assemblyGO:0010257160.075
purine ribonucleoside metabolic processGO:00461284370.075
regulation of purine nucleotide catabolic processGO:00331212050.071
neurogenesisGO:00220081690.071
purine ribonucleoside catabolic processGO:00461303980.068
cellular amine metabolic processGO:0044106410.064
response to peptideGO:1901652650.064
trna metabolic processGO:0006399350.061
regulation of translationGO:0006417890.060
Yeast
carbohydrate derivative biosynthetic processGO:19011372070.059
ribonucleotide biosynthetic processGO:0009260810.059
ribonucleoside catabolic processGO:00424544060.056
glial cell developmentGO:002178270.055
oligodendrocyte differentiationGO:004870970.055
regulation of nucleoside metabolic processGO:00091182090.054
cell developmentGO:00484683280.053
regulation of proteolysisGO:00301622930.053
embryo developmentGO:00097901230.052
Worm
oogenesisGO:004847720.050
organophosphate catabolic processGO:00464344300.050
protein localization to organelleGO:00333652800.049
ion homeostasisGO:00508012300.048
single organism cellular localizationGO:19025803320.047
ribonucleotide catabolic processGO:00092614050.044
trna aminoacylation for protein translationGO:000641880.044
receptor mediated endocytosisGO:0006898840.044
Worm
cellular protein catabolic processGO:00442572610.043
cell cell signalingGO:00072671550.042
purine containing compound catabolic processGO:00725234110.041
carbohydrate metabolic processGO:00059752070.041
reproductive system developmentGO:0061458560.041
positive regulation of transportGO:00510503360.040
glycerol metabolic processGO:000607140.040
response to organonitrogen compoundGO:00102431560.038
negative regulation of protein metabolic processGO:00512483910.038
cellular ketone metabolic processGO:0042180800.037
action potentialGO:0001508340.037
gliogenesisGO:0042063210.036
glycosyl compound catabolic processGO:19016584130.035
cellular macromolecule catabolic processGO:00442653800.035
growthGO:00400072020.035
Worm
reproductive processGO:00224141060.035
endocytosisGO:00068971590.035
Worm
single organism membrane organizationGO:00448022680.034
nucleoside biosynthetic processGO:0009163260.034
negative regulation of protein maturationGO:19033181420.033
small molecule biosynthetic processGO:00442831570.032
positive regulation of purine nucleotide metabolic processGO:19005442270.031
respiratory chain complex iv assemblyGO:000853590.031
regulation of peptidase activityGO:00525471800.029
neuronal action potentialGO:001922890.029
positive regulation of catabolic processGO:00098963100.028
transmembrane transportGO:00550853990.028
establishment of protein localization to organelleGO:00725941720.028
cellular chemical homeostasisGO:00550821800.028
intracellular protein transportGO:00068862700.028
transmission of nerve impulseGO:0019226110.028
cytoplasmic transportGO:00164823790.027
ribose phosphate biosynthetic processGO:0046390820.027
rna processingGO:00063962550.027
nucleoside phosphate catabolic processGO:19012924120.026
negative regulation of protein processingGO:00109551420.026
protein catabolic processGO:00301633250.026
organonitrogen compound biosynthetic processGO:19015662000.026
negative regulation of cellular protein metabolic processGO:00322693530.026
protein acylationGO:00435431380.026
ncrna metabolic processGO:00346601080.025
response to oxygen containing compoundGO:19017003690.025
immune responseGO:00069553070.025
neurological system processGO:00508771630.025
single organism carbohydrate metabolic processGO:00447231930.025
defense responseGO:00069523150.025
membrane organizationGO:00610242920.025
monocarboxylic acid metabolic processGO:00327871850.024
innate immune responseGO:00450871780.024
secretionGO:00469032540.024
positive regulation of cellular amino acid metabolic processGO:004576430.023
maintenance of locationGO:00512351120.023
embryo development ending in birth or egg hatchingGO:0009792340.023
Worm
trna aminoacylationGO:0043039120.023
response to abiotic stimulusGO:00096283360.023
cation homeostasisGO:00550801890.023
cellular cation homeostasisGO:00300031630.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
cellular carbohydrate metabolic processGO:0044262840.022
regulation of cellular amino acid metabolic processGO:000652160.022
negative regulation of programmed cell deathGO:00430693210.022
mitochondrion organizationGO:00070051560.021
reproductionGO:0000003630.021
Worm
regulation of immune responseGO:00507762010.021
response to other organismGO:00517072610.021
response to peptide hormoneGO:0043434610.021
muscle system processGO:0003012810.021
proteolysis involved in cellular protein catabolic processGO:00516032440.020
positive regulation of phosphorylationGO:00423273940.020
positive regulation of apoptotic processGO:00430652460.020
negative regulation of intracellular signal transductionGO:19025321830.019
positive regulation of growthGO:0045927580.019
Worm
multicellular organismal signalingGO:0035637340.019
muscle contractionGO:0006936730.019
positive regulation of cell deathGO:00109422630.019
anterior posterior axis specificationGO:000994820.019
lipid metabolic processGO:00066293810.019
trna splicing via endonucleolytic cleavage and ligationGO:000638870.019
regulation of protein stabilityGO:0031647870.018
establishment of organelle localizationGO:0051656590.018
regulation of endopeptidase activityGO:00525481700.018
reproductive structure developmentGO:0048608550.018
carboxylic acid biosynthetic processGO:0046394970.018
sex differentiationGO:0007548450.018
actin filament based processGO:00300292240.018
female gamete generationGO:000729220.017
amine metabolic processGO:0009308440.017
positive regulation of programmed cell deathGO:00430682490.017
cellular ion homeostasisGO:00068731680.017
negative regulation of apoptotic processGO:00430663160.017
regulation of defense responseGO:00313471540.017
atp catabolic processGO:00062001570.017
negative regulation of peptidase activityGO:0010466910.017
response to biotic stimulusGO:00096072760.017
adult locomotory behaviorGO:000834410.017
regulation of protein maturationGO:19033171500.017
cellular homeostasisGO:00197251960.017
regulation of cysteine type endopeptidase activityGO:20001161270.017
regulation of cellular amine metabolic processGO:0033238110.016
chemical homeostasisGO:00488783060.016
neuromuscular junction developmentGO:000752830.016
developmental process involved in reproductionGO:0003006660.016
negative regulation of cell deathGO:00605483450.016
cellular protein complex assemblyGO:00436231880.016
trna aminoacylation for mitochondrial protein translationGO:007012730.016
regulation of protein processingGO:00706131500.016
secretion by cellGO:00329402260.015
cellular metal ion homeostasisGO:00068751460.015
protein importGO:00170381300.015
histone modificationGO:00165702510.015
negative regulation of phosphorylationGO:00423261740.015
positive regulation of cellular amine metabolic processGO:003324070.015
cofactor biosynthetic processGO:0051188310.015
cytokine productionGO:00018162470.015
single organism reproductive processGO:0044702980.014
positive regulation of ion transportGO:0043270870.014
protein targetingGO:00066051870.014
cell projection organizationGO:00300302520.014
protein stabilizationGO:0050821640.014
quinone metabolic processGO:1901661180.014
cellular lipid metabolic processGO:00442553030.014
segmentationGO:003528240.013
apoptotic signaling pathwayGO:00971902680.013
cellular macromolecular complex assemblyGO:00346223240.013
regulation of protein kinase activityGO:00458592890.013
locomotory behaviorGO:000762610.013
negative regulation of proteolysisGO:00458611320.013
regulation of kinase activityGO:00435493140.013
positive regulation of developmental processGO:00510943140.013
Worm
astrocyte differentiationGO:004870840.013
mitochondrial respiratory chain complex assemblyGO:0033108230.013
metal ion homeostasisGO:00550651690.013
regulation of protein localizationGO:00328802960.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
protein acetylationGO:00064731160.013
regulation of transmembrane transportGO:00347621390.013
metal ion transportGO:00300012720.013
protein localization to membraneGO:00726571600.013
coenzyme biosynthetic processGO:0009108240.013
regulation of cellular ketone metabolic processGO:0010565500.013
regulation of protein transportGO:00512232130.013
n terminal protein amino acid modificationGO:0031365130.012
positive regulation of peptidase activityGO:0010952880.012
regenerationGO:003109940.012
regulation of nucleotide metabolic processGO:00061402690.012
nuclear migrationGO:000709710.012
response to virusGO:00096151260.012
negative regulation of transferase activityGO:00513481240.012
gonad developmentGO:0008406340.012
cellular component morphogenesisGO:00329893140.012
regulation of cytokine productionGO:00018172320.012
cellular response to oxygen containing compoundGO:19017012760.012
regulation of intracellular protein transportGO:00331571230.012
regulation of transferase activityGO:00513383550.012
protein modification by small protein removalGO:0070646920.011
mitochondrial respiratory chain complex iv biogenesisGO:009703450.011
glycosyl compound biosynthetic processGO:1901659270.011
alpha amino acid metabolic processGO:1901605720.011
regulation of growthGO:00400081650.011
Worm
positive regulation of cellular component organizationGO:00511303760.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
blood circulationGO:00080151130.011
establishment of protein localization to membraneGO:00901501210.011
multicellular organismal reproductive processGO:0048609400.011
developmental growthGO:0048589480.011
Worm
negative regulation of catalytic activityGO:00430863350.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
tripartite regional subdivisionGO:000735120.011
nerve developmentGO:002167540.011
dna catabolic process endonucleolyticGO:0000737370.010
microtubule based processGO:00070172100.010
ubiquitin dependent protein catabolic processGO:00065112060.010
regulation of protein catabolic processGO:00421761550.010
rna interferenceGO:001624640.010
Worm
purine ribonucleotide biosynthetic processGO:0009152790.010
negative regulation of growthGO:0045926970.010
negative regulation of endopeptidase activityGO:0010951840.010
negative regulation of protein modification processGO:00314002000.010
cofactor metabolic processGO:0051186870.010
internal protein amino acid acetylationGO:00064751010.010

EIF2B3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.347
disease of metabolismDOID:00146672950.347
mitochondrial metabolism diseaseDOID:700290.129
leigh diseaseDOID:3652160.129
neuropathyDOID:870520.014
neuromuscular diseaseDOID:440380.014
nervous system diseaseDOID:8634310.014
sensory system diseaseDOID:00501552030.014
porphyriaDOID:1326880.012
acute porphyriaDOID:313370.012