Homo sapiens

143 known processes

EIF2B1

eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

(Aliases: MGC117409,MGC125869,EIF2B,MGC125868,EIF2BA)

EIF2B1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.433
nucleoside phosphate catabolic processGO:19012924120.309
purine ribonucleoside triphosphate catabolic processGO:00092073910.280
purine nucleotide catabolic processGO:00061954050.266
nucleoside catabolic processGO:00091644080.260
translationGO:00064121320.229
glycosyl compound catabolic processGO:19016584130.220
purine nucleoside triphosphate catabolic processGO:00091463920.211
ribonucleoside triphosphate catabolic processGO:00092033910.191
vesicle mediated transportGO:00161923710.172
ribonucleotide catabolic processGO:00092614050.149
nucleotide catabolic processGO:00091664080.137
guanosine containing compound catabolic processGO:19010692390.126
purine ribonucleoside metabolic processGO:00461284370.118
nervous system developmentGO:00073992930.106
oligodendrocyte developmentGO:001400360.104
purine nucleoside triphosphate metabolic processGO:00091444120.097
organophosphate catabolic processGO:00464344300.097
nucleoside triphosphate catabolic processGO:00091433940.095
ribonucleoside catabolic processGO:00424544060.093
purine ribonucleoside catabolic processGO:00461303980.090
purine containing compound catabolic processGO:00725234110.089
posttranscriptional regulation of gene expressionGO:00106082130.077
Yeast
positive regulation of hydrolase activityGO:00513453310.077
guanosine containing compound metabolic processGO:19010682440.077
ncrna metabolic processGO:00346601080.073
regulation of purine nucleotide metabolic processGO:19005422640.064
gtp catabolic processGO:00061842370.062
nucleic acid phosphodiester bond hydrolysisGO:00903051020.059
gtp metabolic processGO:00460392390.058
endocytosisGO:00068971590.057
nucleoside triphosphate metabolic processGO:00091414220.054
rna processingGO:00063962550.053
regulation of nucleoside metabolic processGO:00091182090.053
rna interferenceGO:001624640.051
anterior posterior axis specificationGO:000994820.048
purine nucleoside catabolic processGO:00061523980.048
positive regulation of nucleoside metabolic processGO:00459791860.048
cellular amino acid metabolic processGO:00065201160.046
regulation of gtp catabolic processGO:00331241800.045
regulation of purine nucleotide catabolic processGO:00331212050.042
determination of adult lifespanGO:000834020.042
purine ribonucleoside triphosphate metabolic processGO:00092054110.041
segmentationGO:003528240.040
negative regulation of protein metabolic processGO:00512483910.039
neurogenesisGO:00220081690.037
negative regulation of catalytic activityGO:00430863350.037
growthGO:00400072020.036
ribonucleoside triphosphate metabolic processGO:00091994120.035
regulation of gtpase activityGO:00430871800.035
translational initiationGO:0006413480.035
regulation of nucleotide catabolic processGO:00308112050.035
positive regulation of gtpase activityGO:00435471660.035
positive regulation of cellular catabolic processGO:00313312840.034
single organism reproductive processGO:0044702980.033
female gamete generationGO:000729220.033
cytoplasmic transportGO:00164823790.033
regulation of translationGO:0006417890.032
Yeast
positive regulation of nucleotide catabolic processGO:00308131850.032
response to abiotic stimulusGO:00096283360.030
system processGO:00030083490.030
oogenesisGO:004847720.030
positive regulation of purine nucleotide catabolic processGO:00331231850.030
receptor mediated endocytosisGO:0006898840.030
methylationGO:00322591060.030
oligodendrocyte differentiationGO:004870970.029
positive regulation of gtp catabolic processGO:00331261660.029
cellular component morphogenesisGO:00329893140.029
positive regulation of nucleotide metabolic processGO:00459812300.029
trna processingGO:0008033230.028
multicellular organismal agingGO:001025930.027
regulation of cellular amino acid metabolic processGO:000652160.027
cellular macromolecular complex assemblyGO:00346223240.026
tripartite regional subdivisionGO:000735120.026
positive regulation of cellular amino acid metabolic processGO:004576430.025
mitotic cell cycle phase transitionGO:00447721620.025
regulation of cellular amine metabolic processGO:0033238110.024
regulation of protein kinase activityGO:00458592890.024
negative regulation of cell deathGO:00605483450.024
purine ribonucleotide catabolic processGO:00091544040.024
negative regulation of apoptotic processGO:00430663160.024
regulation of growthGO:00400081650.023
carbohydrate derivative biosynthetic processGO:19011372070.023
reproductive processGO:00224141060.023
negative regulation of phosphate metabolic processGO:00459362670.023
negative regulation of intracellular signal transductionGO:19025321830.023
adult locomotory behaviorGO:000834410.023
cellular response to cytokine stimulusGO:00713451810.023
posttranscriptional gene silencingGO:0016441250.022
negative regulation of programmed cell deathGO:00430693210.022
locomotory behaviorGO:000762610.022
protein modification by small protein conjugationGO:00324463420.022
regulation of cellular response to stressGO:00801352440.022
peptidyl lysine modificationGO:00182051440.021
negative regulation of cellular protein metabolic processGO:00322693530.021
trna metabolic processGO:0006399350.021
nucleoside monophosphate catabolic processGO:00091251590.021
macromolecule methylationGO:0043414970.021
embryo developmentGO:00097901230.021
rna modificationGO:0009451270.021
cellular response to dna damage stimulusGO:00069743790.021
cellular amine metabolic processGO:0044106410.020
response to cytokineGO:00340972320.020
internal protein amino acid acetylationGO:00064751010.020
oocyte developmentGO:004859910.020
single organism membrane organizationGO:00448022680.020
amine metabolic processGO:0009308440.020
carbohydrate metabolic processGO:00059752070.019
cell divisionGO:00513011680.019
negative regulation of phosphorus metabolic processGO:00105632670.019
regulation of peptidase activityGO:00525471800.019
ribosome biogenesisGO:0042254480.019
regulation of kinase activityGO:00435493140.018
establishment of ribosome localizationGO:003375340.018
regulation of proteolysisGO:00301622930.018
posttranscriptional gene silencing by rnaGO:0035194250.018
protein maturationGO:00516042330.018
regulation of transferase activityGO:00513383550.018
positive regulation of apoptotic processGO:00430652460.018
negative regulation of protein processingGO:00109551420.018
nucleoside monophosphate metabolic processGO:00091231910.018
positive regulation of catabolic processGO:00098963100.017
dna replicationGO:00062601160.017
histone modificationGO:00165702510.017
protein acylationGO:00435431380.017
cell developmentGO:00484683280.017
regulation of gene expression epigeneticGO:0040029730.017
regulation of cell cycleGO:00517263930.017
biological adhesionGO:00226103310.017
negative regulation of hydrolase activityGO:00513461820.016
nuclear exportGO:0051168690.016
gene silencing by rnaGO:0031047260.016
ribonucleoprotein complex biogenesisGO:00226131160.016
chromatin organizationGO:00063253510.016
regulation of cytokine productionGO:00018172320.016
cellular macromolecule catabolic processGO:00442653800.016
protein catabolic processGO:00301633250.016
regulation of mitotic cell cycle phase transitionGO:19019901180.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
reproductionGO:0000003630.016
central nervous system developmentGO:00074171230.015
rna splicingGO:00083801310.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
ribonucleoprotein complex assemblyGO:0022618780.015
mitotic cell cycle processGO:19030472860.015
small gtpase mediated signal transductionGO:0007264780.015
ras protein signal transductionGO:0007265730.015
cell cell signalingGO:00072671550.015
positive regulation of developmental processGO:00510943140.015
regulation of mapk cascadeGO:00434082620.014
regulation of protein stabilityGO:0031647870.014
protein ubiquitinationGO:00165673140.014
actin filament based processGO:00300292240.014
metal ion homeostasisGO:00550651690.014
endosomal transportGO:00161971290.014
reproductive structure developmentGO:0048608550.014
histone acetylationGO:0016573930.014
response to hypoxiaGO:0001666960.014
protein alkylationGO:0008213740.014
regulation of cysteine type endopeptidase activityGO:20001161270.013
regulation of cellular ketone metabolic processGO:0010565500.013
cellular ketone metabolic processGO:0042180800.013
regulation of response to dna damage stimulusGO:2001020940.013
single organism carbohydrate metabolic processGO:00447231930.013
positive regulation of cell deathGO:00109422630.013
generation of neuronsGO:00486991520.013
cation transportGO:00068123310.013
negative regulation of phosphorylationGO:00423261740.013
regulation of cell cycle processGO:00105642660.013
organelle localizationGO:0051640840.013
nitrogen compound transportGO:00717051910.013
blastoderm segmentationGO:000735020.013
regulation of locomotionGO:00400123290.013
endomembrane system organizationGO:00102561960.013
protein acetylationGO:00064731160.013
small molecule biosynthetic processGO:00442831570.013
ribosome localizationGO:003375040.013
regulation of endopeptidase activityGO:00525481700.013
i kappab kinase nf kappab signalingGO:00072491660.013
neurological system processGO:00508771630.013
ion homeostasisGO:00508012300.012
negative regulation of protein modification processGO:00314002000.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
maintenance of locationGO:00512351120.012
developmental process involved in reproductionGO:0003006660.012
response to nitrogen compoundGO:19016981840.012
metal ion transportGO:00300012720.012
dna geometric changeGO:0032392320.012
positive regulation of cellular component organizationGO:00511303760.012
anterior posterior axis specification embryoGO:000859520.012
immune system developmentGO:00025201950.012
multi organism cellular processGO:00447641560.012
regulation of membrane potentialGO:0042391950.012
cellular ion homeostasisGO:00068731680.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
dephosphorylationGO:00163112090.012
regulation of dna metabolic processGO:00510521530.012
cellular protein catabolic processGO:00442572610.011
protein stabilizationGO:0050821640.011
peptidyl lysine acetylationGO:00183941010.011
mapk cascadeGO:00001652880.011
negative regulation of growthGO:0045926970.011
protein modification by small protein removalGO:0070646920.011
cell morphogenesisGO:00009022960.011
response to oxygen containing compoundGO:19017003690.011
protein localization to organelleGO:00333652800.011
positive regulation of phosphorylationGO:00423273940.011
hematopoietic stem cell differentiationGO:006021840.011
gene silencingGO:0016458490.011
signal transduction by phosphorylationGO:00230142970.011
regulation of anatomical structure morphogenesisGO:00226032860.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
mrna metabolic processGO:00160711750.011
histone methylationGO:0016571600.011
cell cycle checkpointGO:00000751170.011
negative regulation of kinase activityGO:00336731060.011
enzyme linked receptor protein signaling pathwayGO:00071673030.010
secretionGO:00469032540.010
nuclear transportGO:00511691790.010
regulation of ion transportGO:00432691890.010
regulation of protein processingGO:00706131500.010
organic acid biosynthetic processGO:0016053970.010
regulation of protein maturationGO:19033171500.010
negative regulation of cell cycleGO:00457861930.010
atp catabolic processGO:00062001570.010
development of primary sexual characteristicsGO:0045137350.010
anatomical structure formation involved in morphogenesisGO:00486462840.010
epithelium developmentGO:00604292270.010

EIF2B1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.031
inherited metabolic disorderDOID:6552420.027
primary ciliary dyskinesiaDOID:9562270.017
carbohydrate metabolic disorderDOID:2978550.012
congenital disorder of glycosylation type iDOID:0050570160.012
congenital disorder of glycosylationDOID:5212260.012
nervous system diseaseDOID:8634310.011
central nervous system diseaseDOID:3311860.011