Homo sapiens

35 known processes

TXNIP

thioredoxin interacting protein

(Aliases: VDUP1,HHCPA78,THIF,EST01027)

TXNIP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.214
Mouse
carbohydrate metabolic processGO:00059752070.182
cation transportGO:00068123310.163
positive regulation of transportGO:00510503360.159
reactive oxygen species metabolic processGO:0072593750.155
potassium ion transportGO:0006813620.152
ion transmembrane transportGO:00342203380.149
metal ion transportGO:00300012720.125
response to oxygen containing compoundGO:19017003690.121
monocarboxylic acid metabolic processGO:00327871850.110
negative regulation of programmed cell deathGO:00430693210.107
monovalent inorganic cation transportGO:00156721280.106
single organism carbohydrate metabolic processGO:00447231930.101
apoptotic signaling pathwayGO:00971902680.101
protein modification by small protein conjugationGO:00324463420.101
Human
transmembrane transportGO:00550853990.095
inorganic ion transmembrane transportGO:00986602310.090
positive regulation of developmental processGO:00510943140.086
cellular ketone metabolic processGO:0042180800.086
hemopoiesisGO:00300971800.080
negative regulation of growthGO:0045926970.074
positive regulation of cellular amine metabolic processGO:003324070.072
negative regulation of developmental processGO:00510932470.072
intrinsic apoptotic signaling pathwayGO:00971931270.070
potassium ion transmembrane transportGO:0071805600.068
positive regulation of ion transportGO:0043270870.067
lipid metabolic processGO:00066293810.065
cellular potassium ion transportGO:0071804600.064
immune responseGO:00069553070.063
negative regulation of multicellular organismal processGO:00512413170.060
regulation of transmembrane transporter activityGO:0022898740.059
positive regulation of potassium ion transportGO:0043268150.059
mitotic cell cycle phase transitionGO:00447721620.059
g1 s transition of mitotic cell cycleGO:0000082780.056
regulation of intracellular transportGO:00323861950.055
cation transmembrane transportGO:00986552380.055
regulation of metal ion transportGO:00109591200.055
response to decreased oxygen levelsGO:0036293960.054
regulation of potassium ion transmembrane transportGO:1901379200.054
negative regulation of apoptotic processGO:00430663160.054
cellular amino acid metabolic processGO:00065201160.054
positive regulation of phosphorylationGO:00423273940.053
regulation of cell differentiationGO:00455953930.053
cellular carbohydrate metabolic processGO:0044262840.053
cell adhesionGO:00071553250.052
regulation of potassium ion transportGO:0043266240.052
cellular response to endogenous stimulusGO:00714953360.052
regulation of homeostatic processGO:00328441210.051
oxidation reduction processGO:00551143960.051
regulation of cytokine productionGO:00018172320.051
negative regulation of cell cycle processGO:00109481210.050
positive regulation of apoptotic processGO:00430652460.050
response to abiotic stimulusGO:00096283360.050
positive regulation of catabolic processGO:00098963100.047
cellular macromolecule catabolic processGO:00442653800.046
regulation of transporter activityGO:0032409820.046
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.045
inorganic cation transmembrane transportGO:00986621940.045
ion homeostasisGO:00508012300.044
negative regulation of mitotic cell cycleGO:00459301020.044
negative regulation of cell cycleGO:00457861930.044
cellular response to dna damage stimulusGO:00069743790.044
negative regulation of cell cycle g1 s phase transitionGO:1902807290.043
cardiac atrium developmentGO:0003230100.042
multicellular organismal agingGO:001025930.042
regulation of cell growthGO:00015581350.042
regulation of ion transportGO:00432691890.042
ubiquitin dependent protein catabolic processGO:00065112060.041
chemical homeostasisGO:00488783060.040
regulation of cell cycle g1 s phase transitionGO:1902806420.040
generation of precursor metabolites and energyGO:0006091680.040
negative regulation of protein metabolic processGO:00512483910.039
determination of adult lifespanGO:000834020.039
regulation of cellular carbohydrate metabolic processGO:0010675470.039
regulation of cell cycle processGO:00105642660.039
cytokine productionGO:00018162470.039
enzyme linked receptor protein signaling pathwayGO:00071673030.038
Mouse
negative regulation of cell cycle phase transitionGO:1901988890.038
regulation of transmembrane transportGO:00347621390.038
regulation of ion transmembrane transportGO:00347651320.038
mitotic cell cycleGO:00002783260.037
epithelial cell differentiationGO:00308551410.036
negative regulation of catalytic activityGO:00430863350.036
Mouse
regulation of cell cycleGO:00517263930.036
pyruvate metabolic processGO:0006090260.036
negative regulation of cellular protein metabolic processGO:00322693530.036
negative regulation of mitotic cell cycle phase transitionGO:1901991850.036
carbohydrate derivative biosynthetic processGO:19011372070.035
cell activationGO:00017752130.035
protein localization to organelleGO:00333652800.034
Mouse
regulation of potassium ion transmembrane transporter activityGO:1901016160.034
response to oxygen levelsGO:00704821000.034
cell cycle g1 s phase transitionGO:0044843800.033
modification dependent protein catabolic processGO:00199412090.033
regulation of ion transmembrane transporter activityGO:0032412720.033
cardiovascular system developmentGO:00723582620.032
protein localization to nucleusGO:00345041360.032
Mouse
regulation of growthGO:00400081650.032
positive regulation of cell deathGO:00109422630.032
regulation of anatomical structure morphogenesisGO:00226032860.032
regulation of protein localizationGO:00328802960.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
g2 m transition of mitotic cell cycleGO:0000086410.031
regulation of carbohydrate metabolic processGO:0006109540.031
negative regulation of cell deathGO:00605483450.031
hematopoietic or lymphoid organ developmentGO:00485341860.031
regulation of transferase activityGO:00513383550.030
Human
positive regulation of immune system processGO:00026842830.029
leukocyte activationGO:00453211640.029
immune system developmentGO:00025201950.029
positive regulation of immune responseGO:00507781590.029
proteolysis involved in cellular protein catabolic processGO:00516032440.029
post embryonic developmentGO:000979120.029
regulation of protein catabolic processGO:00421761550.029
locomotory behaviorGO:000762610.029
regulation of immune responseGO:00507762010.028
growthGO:00400072020.028
regulation of mitotic cell cycle phase transitionGO:19019901180.028
regulation of protein transportGO:00512232130.027
negative regulation of intracellular signal transductionGO:19025321830.027
response to hormoneGO:00097251750.027
oogenesisGO:004847720.026
positive regulation of cell differentiationGO:00455972110.026
negative regulation of cell proliferationGO:00082852280.026
negative regulation of cell differentiationGO:00455961710.026
regulation of cell cycle phase transitionGO:19019871260.026
negative regulation of t cell apoptotic processGO:007023340.026
biological adhesionGO:00226103310.026
actin filament based processGO:00300292240.026
positive regulation of protein phosphorylationGO:00019343130.026
muscle structure developmentGO:0061061980.026
response to other organismGO:00517072610.025
regulation of cellular amino acid metabolic processGO:000652160.025
negative regulation of phosphate metabolic processGO:00459362670.025
negative regulation of phosphorus metabolic processGO:00105632670.025
maintenance of locationGO:00512351120.025
protein catabolic processGO:00301633250.025
blastoderm segmentationGO:000735020.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
protein ubiquitinationGO:00165673140.024
Human
mitotic cell cycle processGO:19030472860.024
regulation of cellular amine metabolic processGO:0033238110.024
cyclic nucleotide biosynthetic processGO:0009190610.024
nervous system developmentGO:00073992930.024
positive regulation of purine nucleotide biosynthetic processGO:1900373380.024
response to external biotic stimulusGO:00432072610.024
cardiac chamber morphogenesisGO:0003206260.023
t cell activationGO:0042110990.023
protein maturationGO:00516042330.023
positive regulation of cellular component organizationGO:00511303760.023
negative regulation of cell growthGO:0030308830.023
regulation of cell developmentGO:00602841610.023
regulation of g1 s transition of mitotic cell cycleGO:2000045400.023
regulation of purine nucleotide metabolic processGO:19005422640.023
neuromuscular junction developmentGO:000752830.023
regulation of establishment of protein localizationGO:00702012420.023
innate immune responseGO:00450871780.022
response to oxidative stressGO:00069791210.022
Mouse
macromolecular complex disassemblyGO:0032984600.022
response to organonitrogen compoundGO:00102431560.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.022
Mouse
cellular response to organonitrogen compoundGO:00714171240.022
positive regulation of nucleotide metabolic processGO:00459812300.022
detection of chemical stimulusGO:0009593550.022
amine metabolic processGO:0009308440.022
positive regulation of cellular catabolic processGO:00313312840.021
negative regulation of phosphorylationGO:00423261740.021
positive regulation of mapk cascadeGO:00434101900.021
cellular homeostasisGO:00197251960.021
regulation of tor signalingGO:0032006300.021
protein targeting to nucleusGO:00447441040.021
Mouse
cellular lipid metabolic processGO:00442553030.021
defense responseGO:00069523150.021
cellular response to oxygen containing compoundGO:19017012760.021
regulation of cellular ketone metabolic processGO:0010565500.021
negative regulation of cellular component organizationGO:00511292350.021
regulation of membrane potentialGO:0042391950.021
cell divisionGO:00513011680.021
leukocyte differentiationGO:0002521980.020
immune response regulating signaling pathwayGO:0002764970.020
regulation of proteolysisGO:00301622930.020
lymphocyte activationGO:00466491330.020
regulation of i kappab kinase nf kappab signalingGO:00431221620.020
regulation of leukocyte activationGO:00026941150.020
negative regulation of catabolic processGO:00098951040.020
regulation of mitotic cell cycleGO:00073461890.020
cellular response to oxidative stressGO:0034599850.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
cell developmentGO:00484683280.019
cell cycle g2 m phase transitionGO:0044839430.019
protein complex disassemblyGO:0043241520.019
response to peptideGO:1901652650.019
regulation of cytoplasmic transportGO:19036491490.019
regulation of protein processingGO:00706131500.019
cell type specific apoptotic processGO:00972851250.019
response to lipidGO:00339932060.019
activation of immune responseGO:00022531140.019
regulation of lymphocyte activationGO:00512491030.019
symbiosis encompassing mutualism through parasitismGO:00444031560.019
regulation of cellular response to stressGO:00801352440.019
regulation of leukocyte differentiationGO:1902105610.019
intracellular protein transportGO:00068862700.018
Mouse
cardiac atrium morphogenesisGO:000320970.018
positive regulation of transferase activityGO:00513472270.018
Human
glycoprotein metabolic processGO:00091001100.018
cyclic purine nucleotide metabolic processGO:0052652600.018
negative regulation of protein processingGO:00109551420.018
regulation of protein kinase activityGO:00458592890.018
rna catabolic processGO:0006401710.018
female gamete generationGO:000729220.018
positive regulation of secretion by cellGO:19035321080.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
regulation of neural precursor cell proliferationGO:200017740.018
regulation of nucleotide metabolic processGO:00061402690.018
segmentationGO:003528240.018
cell growthGO:00160491600.018
anatomical structure homeostasisGO:00602491000.018
small gtpase mediated signal transductionGO:0007264780.018
purine containing compound biosynthetic processGO:0072522880.018
negative regulation of protein modification processGO:00314002000.018
regulation of bindingGO:00510981110.018
cellular component morphogenesisGO:00329893140.017
negative regulation of protein maturationGO:19033181420.017
mrna metabolic processGO:00160711750.017
cellular protein catabolic processGO:00442572610.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of protein maturationGO:19033171500.017
positive regulation of hydrolase activityGO:00513453310.017
regulation of purine nucleotide biosynthetic processGO:1900371500.017
regulation of protein localization to nucleusGO:1900180850.017
t cell differentiation in thymusGO:003307740.017
rna processingGO:00063962550.017
regulation of endothelial cell differentiationGO:004560140.017
ribonucleotide catabolic processGO:00092614050.017
coenzyme metabolic processGO:0006732650.017
nucleoside catabolic processGO:00091644080.017
immune effector processGO:00022521590.017
regulation of protein modification by small protein conjugation or removalGO:19033201070.017
Human
positive regulation of programmed cell deathGO:00430682490.017
cellular response to hormone stimulusGO:00328701250.016
negative regulation of cellular amine metabolic processGO:003323930.016
ribonucleoside triphosphate catabolic processGO:00092033910.016
regulation of intracellular protein transportGO:00331571230.016
fatty acid metabolic processGO:00066311150.016
cellular response to reactive oxygen speciesGO:0034614500.016
multicellular organismal homeostasisGO:0048871670.016
response to inorganic substanceGO:00100351270.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
mapk cascadeGO:00001652880.016
circulatory system developmentGO:00723592620.016
regulation of t cell activationGO:0050863770.016
positive regulation of protein catabolic processGO:0045732750.016
tissue regenerationGO:004224630.016
regulation of muscle tissue developmentGO:1901861260.016
positive regulation of cytokine productionGO:00018191670.016
negative regulation of hydrolase activityGO:00513461820.016
response to hypoxiaGO:0001666960.016
actin filament organizationGO:00070151280.016
regulation of cell migrationGO:00303342890.016
regulation of defense responseGO:00313471540.016
cell substrate adhesionGO:00315891320.015
regulation of ion homeostasisGO:2000021730.015
single organism cellular localizationGO:19025803320.015
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.015
dephosphorylationGO:00163112090.015
negative regulation of muscle tissue developmentGO:1901862110.015
nucleoside triphosphate metabolic processGO:00091414220.015
single organismal cell cell adhesionGO:00163371480.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
regulation of membrane depolarizationGO:0003254190.015
response to biotic stimulusGO:00096072760.015
posttranscriptional regulation of gene expressionGO:00106082130.015
cell projection organizationGO:00300302520.015
organic acid biosynthetic processGO:0016053970.015
cell morphogenesisGO:00009022960.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
actin cytoskeleton organizationGO:00300362070.015
regulation of endopeptidase activityGO:00525481700.015
endosomal transportGO:00161971290.015
protein oligomerizationGO:00512591730.015
nucleocytoplasmic transportGO:00069131760.015
Mouse
response to organic cyclic compoundGO:00140702040.015
positive regulation of leukocyte differentiationGO:1902107370.015
ossificationGO:00015031210.015
secretion by cellGO:00329402260.015
proteasomal protein catabolic processGO:00104981760.015
organophosphate catabolic processGO:00464344300.015
negative regulation of striated muscle tissue developmentGO:0045843110.015
nuclear importGO:00511701060.015
Mouse
carboxylic acid biosynthetic processGO:0046394970.015
spermatid differentiationGO:004851540.015
membrane organizationGO:00610242920.015
rna interferenceGO:001624640.015
regulation of cytoskeleton organizationGO:00514931770.014
modification dependent macromolecule catabolic processGO:00436322120.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
purine ribonucleotide catabolic processGO:00091544040.014
positive regulation of protein transportGO:00512221350.014
reproductive processGO:00224141060.014
t cell homeostasisGO:004302930.014
organ morphogenesisGO:00098871470.014
cellular response to lipidGO:00713961270.014
cell cycle phase transitionGO:00447701730.014
positive regulation of lymphocyte activationGO:0051251730.014
regulation of actin cytoskeleton organizationGO:00329561160.014
cellular chemical homeostasisGO:00550821800.014
single organism carbohydrate catabolic processGO:0044724330.014
purine nucleoside triphosphate catabolic processGO:00091463920.014
establishment of protein localization to organelleGO:00725941720.014
Mouse
ras protein signal transductionGO:0007265730.014
dna repairGO:00062811980.014
memoryGO:000761330.014
actin mediated cell contractionGO:0070252120.013
glycosyl compound catabolic processGO:19016584130.013
positive regulation of camp biosynthetic processGO:0030819350.013
positive regulation of organelle organizationGO:00106381950.013
microtubule based processGO:00070172100.013
positive regulation of proteolysisGO:00458621420.013
regulation of cell adhesionGO:00301551660.013
single organism nuclear importGO:19025931040.013
Mouse
syncytium formation by plasma membrane fusionGO:000076820.013
positive regulation of cell adhesionGO:0045785840.013
regulation of protein targetingGO:1903533910.013
purine ribonucleotide biosynthetic processGO:0009152790.013
negative regulation of locomotionGO:00400131180.013
regulation of camp metabolic processGO:0030814520.013
regulation of protein complex assemblyGO:00432541470.013
regulation of apoptotic signaling pathwayGO:20012331750.013
cellular response to growth factor stimulusGO:00713631970.013
myeloid cell differentiationGO:00300991170.013
response to bacteriumGO:00096171440.013
nitrogen compound transportGO:00717051910.013
cellular response to glucocorticoid stimulusGO:007138540.013
regulation of multi organism processGO:00439001570.013
protein deubiquitinationGO:0016579790.013
regulation of response to external stimulusGO:00321012220.013
regulation of mapk cascadeGO:00434082620.013
organic hydroxy compound metabolic processGO:19016151470.013
purine nucleoside catabolic processGO:00061523980.013
lymphocyte homeostasisGO:000226040.013
mononuclear cell proliferationGO:0032943710.013
regulation of vasculature developmentGO:1901342970.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
nucleotide catabolic processGO:00091664080.012
regulation of cellular protein catabolic processGO:1903362960.012
cellular response to organic cyclic compoundGO:00714071270.012
cardiac chamber developmentGO:0003205300.012
gtp metabolic processGO:00460392390.012
mrna processingGO:00063971330.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
regulation of gene expression epigeneticGO:0040029730.012
alcohol metabolic processGO:00060661140.012
interspecies interaction between organismsGO:00444191560.012
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.012
regulation of innate immune responseGO:0045088970.012
regulation of ras protein signal transductionGO:00465781550.012
immune response activating signal transductionGO:0002757900.012
single organism membrane organizationGO:00448022680.012
camp biosynthetic processGO:0006171470.012
organonitrogen compound biosynthetic processGO:19015662000.012
negative regulation of skeletal muscle tissue developmentGO:004864220.012
regulation of nucleocytoplasmic transportGO:0046822980.012
protein homooligomerizationGO:00512601000.012
secretionGO:00469032540.012
cardiac ventricle developmentGO:0003231230.012
anterior posterior axis specificationGO:000994820.012
stem cell divisionGO:001714520.012
purine ribonucleoside metabolic processGO:00461284370.012
adult locomotory behaviorGO:000834410.012
positive regulation of innate immune responseGO:0045089790.012
rho protein signal transductionGO:0007266260.012
signal transduction by p53 class mediatorGO:0072331720.012
cellular amine metabolic processGO:0044106410.012
osteoblast differentiationGO:0001649920.012
neuron projection developmentGO:00311751060.012
multicellular organism reproductionGO:0032504420.012
rhythmic behaviorGO:000762220.012
regenerationGO:003109940.012
negative regulation of protein phosphorylationGO:00019331400.012
response to reactive oxygen speciesGO:0000302610.012
sensory perception of tasteGO:0050909360.012
somatic stem cell maintenanceGO:003501940.012
reactive oxygen species biosynthetic processGO:190340940.012
negative regulation of cell motilityGO:20001461040.012
positive regulation of cell activationGO:0050867810.012
spermatid developmentGO:000728640.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.012
negative regulation of immune system processGO:00026831360.012
protein targetingGO:00066051870.011
Mouse
microtubule cytoskeleton organizationGO:00002261760.011
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.011
regulation of cell activationGO:00508651250.011
stress activated mapk cascadeGO:0051403930.011
lymphocyte proliferationGO:0046651700.011
regulation of cellular component biogenesisGO:00440872810.011
positive regulation of t cell tolerance inductionGO:000266620.011
cation homeostasisGO:00550801890.011
response to nitrogen compoundGO:19016981840.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
membrane depolarizationGO:0051899260.011
oocyte developmentGO:004859910.011
regulation of purine nucleotide catabolic processGO:00331212050.011
response to cytokineGO:00340972320.011
reproductionGO:0000003630.011
nuclear transportGO:00511691790.011
Mouse
response to peptide hormoneGO:0043434610.011
cellular response to starvationGO:0009267580.011
multi organism reproductive processGO:0044703540.011
heart developmentGO:0007507950.011
regulation of dna metabolic processGO:00510521530.011
protein processingGO:00164852260.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
monosaccharide metabolic processGO:0005996740.011
chromatin organizationGO:00063253510.011
divalent inorganic cation homeostasisGO:00725071360.011
anion transportGO:00068201610.011
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
ribonucleoside catabolic processGO:00424544060.011
response to axon injuryGO:004867810.011
response to woundingGO:00096111680.011
regulation of cellular response to growth factor stimulusGO:0090287760.011
cytoplasmic transportGO:00164823790.011
Mouse
regulation of anatomical structure sizeGO:00900661010.011
negative regulation of kinase activityGO:00336731060.011
cellular macromolecular complex assemblyGO:00346223240.011
regulation of secretion by cellGO:19035301770.011
regulation of ras gtpase activityGO:00323181280.011
post embryonic organ developmentGO:004856910.010
negative regulation of blood pressureGO:004577630.010
neural tube formationGO:000184130.010
i kappab kinase nf kappab signalingGO:00072491660.010
detection of chemical stimulus involved in sensory perceptionGO:0050907330.010
purine ribonucleoside catabolic processGO:00461303980.010
regulation of kinase activityGO:00435493140.010
regulation of peptidase activityGO:00525471800.010
monocarboxylic acid biosynthetic processGO:0072330670.010
defense response to other organismGO:00985421290.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010
response to light stimulusGO:0009416870.010
nucleoside triphosphate catabolic processGO:00091433940.010
negative regulation of homeostatic processGO:0032845590.010
sex determinationGO:000753030.010
response to virusGO:00096151260.010
blood vessel developmentGO:00015681720.010
regulation of ligase activityGO:0051340290.010
Human
protein importGO:00170381300.010
Mouse
regulation of gtp catabolic processGO:00331241800.010
neurogenesisGO:00220081690.010
regulation of generation of precursor metabolites and energyGO:0043467270.010
cardiac ventricle morphogenesisGO:0003208200.010
peptidyl tyrosine modificationGO:00182121700.010
response to endoplasmic reticulum stressGO:0034976490.010
g protein coupled receptor signaling pathwayGO:00071862070.010
somatic muscle developmentGO:000752510.010

TXNIP disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
emery dreifuss muscular dystrophyDOID:1172660.635
musculoskeletal system diseaseDOID:172230.635
muscle tissue diseaseDOID:661130.635
muscular dystrophyDOID:9884510.635
muscular diseaseDOID:00800001140.635
myopathyDOID:4231040.635
disease of metabolismDOID:00146672950.087
inherited metabolic disorderDOID:6552420.069
cardiovascular system diseaseDOID:12871060.023
disease of cellular proliferationDOID:145661740.014
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
heart diseaseDOID:114680.013
sensory system diseaseDOID:00501552030.012
nervous system diseaseDOID:8634310.012
central nervous system diseaseDOID:3311860.010