Homo sapiens

65 known processes

LIG4

ligase IV, DNA, ATP-dependent

LIG4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna ligationGO:0006266100.999
pro b cell differentiationGO:000232810.983
Mouse
dna ligation involved in dna repairGO:005110340.874
v d j recombinationGO:003315130.869
single strand break repairGO:000001260.595
negative regulation of programmed cell deathGO:00430693210.332
Mouse
cellular macromolecule catabolic processGO:00442653800.266
fibroblast proliferationGO:0048144330.237
Mouse
negative regulation of cell deathGO:00605483450.230
Mouse
leukocyte differentiationGO:0002521980.204
Mouse
negative regulation of apoptotic processGO:00430663160.200
Mouse
response to radiationGO:00093141510.198
t cell differentiation in thymusGO:003307740.191
Mouse
cell activationGO:00017752130.187
Mouse
double strand break repairGO:00063021010.186
somatic diversification of immunoglobulins involved in immune responseGO:000220830.171
Mouse
t cell activationGO:0042110990.161
Mouse
regulation of cell differentiationGO:00455953930.159
Mouse
leukocyte activationGO:00453211640.152
Mouse
lymphocyte activationGO:00466491330.146
Mouse
response to gamma radiationGO:0010332140.140
Mouse
nucleic acid phosphodiester bond hydrolysisGO:00903051020.131
response to ionizing radiationGO:0010212650.119
nervous system developmentGO:00073992930.118
Mouse
positive regulation of dna metabolic processGO:0051054730.117
cell developmentGO:00484683280.115
Mouse
cellular response to dna damage stimulusGO:00069743790.114
leukocyte mediated immunityGO:0002443590.108
Mouse
post embryonic developmentGO:000979120.097
lymphocyte mediated immunityGO:0002449480.086
Mouse
positive regulation of cell proliferationGO:00082843010.085
Mouse
regulation of neuron apoptotic processGO:0043523350.082
Mouse
adaptive immune responseGO:0002250490.081
Mouse
regulation of cell developmentGO:00602841610.076
Mouse
positive regulation of cell developmentGO:0010720920.075
Mouse
cell activation involved in immune responseGO:0002263300.071
Mouse
dna catabolic process endonucleolyticGO:0000737370.064
neuron apoptotic processGO:0051402390.064
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.060
Mouse
cellular amine metabolic processGO:0044106410.058
dna repairGO:00062811980.058
regulation of nervous system developmentGO:0051960880.058
Mouse
response to oxidative stressGO:00069791210.058
non recombinational repairGO:0000726140.057
immune system developmentGO:00025201950.056
response to abiotic stimulusGO:00096283360.056
dephosphorylationGO:00163112090.055
generation of neuronsGO:00486991520.055
Mouse
somatic diversification of immune receptorsGO:000220080.053
regulation of fibroblast proliferationGO:0048145320.051
Mouse
female gamete generationGO:000729220.049
leukocyte activation involved in immune responseGO:0002366300.048
Mouse
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.047
Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.044
Mouse
b cell activationGO:0042113330.043
Mouse
lymphocyte differentiationGO:0030098350.042
Mouse
response to oxygen containing compoundGO:19017003690.040
regulation of cellular amino acid metabolic processGO:000652160.040
protein catabolic processGO:00301633250.039
lymphocyte activation involved in immune responseGO:0002285200.039
Mouse
dna damage response detection of dna damageGO:004276930.037
nucleoside triphosphate metabolic processGO:00091414220.037
amine metabolic processGO:0009308440.035
immune responseGO:00069553070.034
Mouse
carbohydrate metabolic processGO:00059752070.034
positive regulation of nervous system developmentGO:0051962540.033
Mouse
determination of adult lifespanGO:000834020.033
regulation of ligase activityGO:0051340290.032
positive regulation of ligase activityGO:0051351190.031
single organism carbohydrate metabolic processGO:00447231930.031
regulation of cellular ketone metabolic processGO:0010565500.029
regulation of dna metabolic processGO:00510521530.028
production of molecular mediator of immune responseGO:0002440370.028
Mouse
lipid metabolic processGO:00066293810.026
negative regulation of protein metabolic processGO:00512483910.026
ubiquitin dependent protein catabolic processGO:00065112060.025
positive regulation of cellular component organizationGO:00511303760.025
cellular ketone metabolic processGO:0042180800.025
cellular amino acid metabolic processGO:00065201160.024
negative regulation of cellular protein metabolic processGO:00322693530.024
immune effector processGO:00022521590.024
Mouse
regulation of cell cycleGO:00517263930.024
regulation of proteolysisGO:00301622930.024
oogenesisGO:004847720.023
somatic recombination of immunoglobulin gene segmentsGO:001644740.023
Mouse
oxidation reduction processGO:00551143960.023
protein maturationGO:00516042330.023
organophosphate catabolic processGO:00464344300.023
proteolysis involved in cellular protein catabolic processGO:00516032440.022
wnt signaling pathwayGO:00160551560.022
double strand break repair via nonhomologous end joiningGO:0006303100.022
cytoplasmic transportGO:00164823790.021
macromolecule glycosylationGO:0043413630.021
positive regulation of nucleoside metabolic processGO:00459791860.021
positive regulation of cellular catabolic processGO:00313312840.021
receptor metabolic processGO:0043112810.021
lipid biosynthetic processGO:00086101770.021
cellular protein catabolic processGO:00442572610.021
protein processingGO:00164852260.020
rna processingGO:00063962550.019
locomotory behaviorGO:000762610.019
regulation of nucleotide metabolic processGO:00061402690.019
single organism cellular localizationGO:19025803320.019
modification dependent protein catabolic processGO:00199412090.018
metal ion transportGO:00300012720.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
purine nucleotide catabolic processGO:00061954050.018
peptidyl serine phosphorylationGO:00181051010.018
isotype switchingGO:004519030.018
Mouse
protein localization to organelleGO:00333652800.017
regulation of cellular amine metabolic processGO:0033238110.017
posttranscriptional regulation of gene expressionGO:00106082130.017
canonical wnt signaling pathwayGO:00600701160.017
negative regulation of phosphorus metabolic processGO:00105632670.017
protein glycosylationGO:0006486620.017
mitotic nuclear divisionGO:00070671190.017
glycosyl compound catabolic processGO:19016584130.017
cellular lipid metabolic processGO:00442553030.017
positive regulation of cell differentiationGO:00455972110.016
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
nucleoside catabolic processGO:00091644080.016
regulation of protein kinase activityGO:00458592890.016
glycoprotein biosynthetic processGO:0009101910.016
apoptotic signaling pathwayGO:00971902680.016
positive regulation of developmental processGO:00510943140.015
Mouse
phospholipid metabolic processGO:0006644990.015
maintenance of locationGO:00512351120.015
cation transportGO:00068123310.015
memoryGO:000761330.015
regulation of cell cycle processGO:00105642660.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.015
positive regulation of nucleotide metabolic processGO:00459812300.015
positive regulation of transportGO:00510503360.015
regulation of canonical wnt signaling pathwayGO:0060828880.015
ribonucleotide catabolic processGO:00092614050.015
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.015
Mouse
regulation of purine nucleotide catabolic processGO:00331212050.015
negative regulation of cellular component organizationGO:00511292350.015
protein ubiquitinationGO:00165673140.015
positive regulation of proteolysisGO:00458621420.015
regulation of anatomical structure morphogenesisGO:00226032860.014
nucleoside triphosphate catabolic processGO:00091433940.014
mitotic cell cycle processGO:19030472860.014
purine containing compound catabolic processGO:00725234110.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
negative regulation of neuron apoptotic processGO:0043524230.014
Mouse
cell morphogenesisGO:00009022960.014
glycosylationGO:0070085710.014
negative regulation of catalytic activityGO:00430863350.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of cell morphogenesisGO:00226041530.014
i kappab kinase nf kappab signalingGO:00072491660.014
protein polyubiquitinationGO:00002091100.014
blastoderm segmentationGO:000735020.014
meiotic chromosome segregationGO:004513240.013
positive regulation of phosphorylationGO:00423273940.013
neurological system processGO:00508771630.013
regulation of establishment of protein localizationGO:00702012420.013
system processGO:00030083490.013
atp catabolic processGO:00062001570.013
chemical homeostasisGO:00488783060.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
regulation of nucleotide catabolic processGO:00308112050.013
negative regulation of axonogenesisGO:005077140.013
regulation of endocytosisGO:0030100720.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
regulation of wnt signaling pathwayGO:00301111230.013
regulation of purine nucleotide metabolic processGO:19005422640.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
regulation of protein processingGO:00706131500.012
spermatid developmentGO:000728640.012
neuromuscular junction developmentGO:000752830.012
taxisGO:00423301570.012
regulation of protein stabilityGO:0031647870.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of protein catabolic processGO:00421761550.012
response to inorganic substanceGO:00100351270.012
myeloid leukocyte differentiationGO:0002573600.012
negative regulation of cellular amine metabolic processGO:003323930.012
negative regulation of transportGO:00510511760.012
rhythmic behaviorGO:000762220.012
organophosphate biosynthetic processGO:00904071630.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
intracellular protein transportGO:00068862700.012
ribonucleoside catabolic processGO:00424544060.012
myeloid cell differentiationGO:00300991170.012
regulation of mitotic cell cycleGO:00073461890.012
reactive oxygen species biosynthetic processGO:190340940.012
regulation of protein localizationGO:00328802960.012
cellular component morphogenesisGO:00329893140.012
compound eye developmentGO:004874910.011
cellular homeostasisGO:00197251960.011
hemopoiesisGO:00300971800.011
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.011
negative regulation of protein phosphorylationGO:00019331400.011
myoblast fusionGO:000752010.011
central nervous system developmentGO:00074171230.011
Mouse
negative regulation of phosphate metabolic processGO:00459362670.011
mitotic cell cycle phase transitionGO:00447721620.011
regulation of cellular response to stressGO:00801352440.011
ras protein signal transductionGO:0007265730.011
positive regulation of cell deathGO:00109422630.011
translationGO:00064121320.011
single organism membrane organizationGO:00448022680.011
positive regulation of hydrolase activityGO:00513453310.011
negative regulation of intracellular signal transductionGO:19025321830.011
positive regulation of apoptotic processGO:00430652460.011
regulation of protein maturationGO:19033171500.011
regulation of meiotic cell cycleGO:005144540.011
regulation of kinase activityGO:00435493140.011
lysosomal transportGO:0007041330.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
regulation of gene expression epigeneticGO:0040029730.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
purine ribonucleoside triphosphate metabolic processGO:00092054110.011
epithelial cell proliferationGO:00506731280.011
spermatid differentiationGO:004851540.011
regulation of response to external stimulusGO:00321012220.011
regulation of cytokine productionGO:00018172320.011
cell part morphogenesisGO:00329901370.010
receptor internalizationGO:0031623430.010
nuclear transportGO:00511691790.010
cellular response to transforming growth factor beta stimulusGO:0071560940.010
modification dependent macromolecule catabolic processGO:00436322120.010
glycerophospholipid metabolic processGO:0006650840.010
negative regulation of protein processingGO:00109551420.010
nucleotide catabolic processGO:00091664080.010
cellular response to oxidative stressGO:0034599850.010
regulation of ras protein signal transductionGO:00465781550.010
negative regulation of proteolysisGO:00458611320.010
biological adhesionGO:00226103310.010
reactive nitrogen species metabolic processGO:200105730.010
actin cytoskeleton organizationGO:00300362070.010
reactive oxygen species metabolic processGO:0072593750.010
sequestering of metal ionGO:0051238240.010
protein autophosphorylationGO:00467771230.010

LIG4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
brain diseaseDOID:936730.069
electroclinical syndromeDOID:0050701320.069
central nervous system diseaseDOID:3311860.069
nervous system diseaseDOID:8634310.069
epilepsy syndromeDOID:1826410.069
neonatal period electroclinical syndromeDOID:0050702190.069
connective tissue diseaseDOID:651090.046
musculoskeletal system diseaseDOID:172230.046
bone diseaseDOID:0080001880.046
disease of cellular proliferationDOID:145661740.043
cancerDOID:1621670.027
sensory system diseaseDOID:00501552030.017
organ system cancerDOID:00506861640.014
disease of metabolismDOID:00146672950.014
idiopathic generalized epilepsyDOID:1827210.013
immune system diseaseDOID:29141550.012
hematopoietic system diseaseDOID:741000.012
bone remodeling diseaseDOID:0080005260.011
retinal diseaseDOID:56791180.011
eye diseaseDOID:56141490.011
eye and adnexa diseaseDOID:14921500.011
osteopetrosisDOID:1353390.010
osteosclerosisDOID:4254160.010
immune system cancerDOID:0060083360.006
hematologic cancerDOID:2531360.006
primary immunodeficiency diseaseDOID:612360.003
bone marrow cancerDOID:4960100.001
combined t cell and b cell immunodeficiencyDOID:628120.001
myelomaDOID:007000470.001