Homo sapiens

17 known processes

LIG1

ligase I, DNA, ATP-dependent

(Aliases: MGC117397,MGC130025)

LIG1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
multicellular organismal agingGO:001025930.225
determination of adult lifespanGO:000834020.200
dna repairGO:00062811980.189
Yeast Mouse
microtubule based processGO:00070172100.178
dna dependent dna replicationGO:0006261440.154
Yeast
mitotic cell cycle processGO:19030472860.154
base excision repairGO:0006284210.150
Yeast
double strand break repairGO:00063021010.147
Mouse
nucleotide excision repairGO:0006289310.143
Yeast
dna recombinationGO:0006310770.136
Yeast
cellular response to dna damage stimulusGO:00069743790.134
Yeast Mouse
meiosis iGO:000712740.133
mitotic cell cycleGO:00002783260.125
Yeast
post embryonic developmentGO:000979120.121
microtubule organizing center organizationGO:0031023620.116
dna replicationGO:00062601160.111
Yeast Mouse
microtubule cytoskeleton organizationGO:00002261760.096
dna synthesis involved in dna repairGO:000073160.095
negative regulation of chromatin silencingGO:003193640.085
purine nucleoside monophosphate catabolic processGO:00091281580.085
mitotic cell cycle phase transitionGO:00447721620.081
regulation of cell cycle processGO:00105642660.080
ribonucleoside triphosphate catabolic processGO:00092033910.079
ribonucleotide catabolic processGO:00092614050.074
centrosome organizationGO:0051297580.072
cellular amino acid metabolic processGO:00065201160.068
chromosome segregationGO:00070591140.068
dna strand elongationGO:002261650.065
Yeast
purine ribonucleoside monophosphate catabolic processGO:00091691580.065
nucleoside monophosphate metabolic processGO:00091231910.061
embryo developmentGO:00097901230.060
Worm
female gamete generationGO:000729220.060
reproductive processGO:00224141060.058
dna biosynthetic processGO:0071897400.056
chromatin modificationGO:00165682980.055
nucleoside phosphate catabolic processGO:19012924120.054
meiotic chromosome segregationGO:004513240.051
organelle fissionGO:00482851490.050
purine ribonucleoside triphosphate catabolic processGO:00092073910.050
ribonucleoside triphosphate metabolic processGO:00091994120.050
nuclear divisionGO:00002801280.048
organophosphate catabolic processGO:00464344300.047
purine nucleotide catabolic processGO:00061954050.046
atp catabolic processGO:00062001570.045
regulation of cell cycleGO:00517263930.044
regulation of chromosome segregationGO:0051983440.043
nucleoside triphosphate catabolic processGO:00091433940.043
cell cycle phase transitionGO:00447701730.042
purine ribonucleoside triphosphate metabolic processGO:00092054110.040
chromatin organizationGO:00063253510.039
oogenesisGO:004847720.039
regulation of intracellular transportGO:00323861950.039
regulation of mitotic cell cycleGO:00073461890.038
negative regulation of mitotic cell cycleGO:00459301020.038
male meiosisGO:000714010.037
dna conformation changeGO:00711031130.037
deoxyribose phosphate metabolic processGO:001969260.037
response to abiotic stimulusGO:00096283360.034
hematopoietic or lymphoid organ developmentGO:00485341860.033
glycosyl compound catabolic processGO:19016584130.033
purine containing compound catabolic processGO:00725234110.031
purine nucleoside catabolic processGO:00061523980.029
atp metabolic processGO:00460341760.029
embryo development ending in birth or egg hatchingGO:0009792340.029
Worm
ribonucleoside catabolic processGO:00424544060.029
single organism reproductive processGO:0044702980.029
covalent chromatin modificationGO:00165692540.028
negative regulation of cell cycleGO:00457861930.028
nucleoside catabolic processGO:00091644080.028
response to ionizing radiationGO:0010212650.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
purine ribonucleotide catabolic processGO:00091544040.028
regulation of cellular ketone metabolic processGO:0010565500.028
purine ribonucleoside metabolic processGO:00461284370.027
lymphocyte activationGO:00466491330.027
positive regulation of hydrolase activityGO:00513453310.026
blastocyst developmentGO:000182430.026
meiotic chromosome separationGO:005130730.026
purine nucleoside triphosphate catabolic processGO:00091463920.026
mitotic cell cycle checkpointGO:0007093680.025
immune effector processGO:00022521590.025
developmental process involved in reproductionGO:0003006660.025
vesicle mediated transportGO:00161923710.025
Worm
protein alkylationGO:0008213740.025
establishment of nucleus localizationGO:004002310.024
nucleotide catabolic processGO:00091664080.023
nucleoside triphosphate metabolic processGO:00091414220.023
regulation of cellular amino acid metabolic processGO:000652160.023
methylationGO:00322591060.022
negative regulation of phosphate metabolic processGO:00459362670.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
nucleoside monophosphate catabolic processGO:00091251590.022
dna damage checkpointGO:0000077680.022
cell cycle checkpointGO:00000751170.022
cell projection morphogenesisGO:00488581290.022
negative regulation of mitotic cell cycle phase transitionGO:1901991850.022
response to fungusGO:000962040.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
interspecies interaction between organismsGO:00444191560.021
cellular component morphogenesisGO:00329893140.021
sister chromatid segregationGO:0000819540.021
cellular ketone metabolic processGO:0042180800.021
positive regulation of cellular amine metabolic processGO:003324070.021
negative regulation of cell cycle processGO:00109481210.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
oocyte differentiationGO:000999420.021
reproductionGO:0000003630.021
sensory organ developmentGO:0007423520.020
positive regulation of nuclease activityGO:003207550.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
spindle organizationGO:0007051530.020
epithelium developmentGO:00604292270.020
cellular response to endogenous stimulusGO:00714953360.019
mitotic nuclear divisionGO:00070671190.019
ribonucleoside monophosphate catabolic processGO:00091581580.019
reproductive structure developmentGO:0048608550.019
endomembrane system organizationGO:00102561960.019
sex differentiationGO:0007548450.019
response to other organismGO:00517072610.019
protein modification by small protein conjugationGO:00324463420.018
organ morphogenesisGO:00098871470.018
response to hormoneGO:00097251750.018
nervous system developmentGO:00073992930.018
regulation of establishment of protein localizationGO:00702012420.018
immune system developmentGO:00025201950.018
rna phosphodiester bond hydrolysisGO:0090501350.018
regulation of response to dna damage stimulusGO:2001020940.017
purine ribonucleoside catabolic processGO:00461303980.017
negative regulation of programmed cell deathGO:00430693210.017
multi organism cellular processGO:00447641560.017
regulation of cytoskeleton organizationGO:00514931770.017
positive regulation of transportGO:00510503360.017
regulation of gene expression epigeneticGO:0040029730.017
cell divisionGO:00513011680.017
cell projection organizationGO:00300302520.017
rna catabolic processGO:0006401710.017
response to uvGO:0009411730.017
cell part morphogenesisGO:00329901370.017
cellular amine metabolic processGO:0044106410.017
nucleic acid phosphodiester bond hydrolysisGO:00903051020.017
regulation of transcription by chromatin organizationGO:003440110.017
response to external biotic stimulusGO:00432072610.017
chromatin remodelingGO:0006338550.016
immune responseGO:00069553070.016
viral life cycleGO:00190581320.016
regulation of immune effector processGO:0002697910.016
response to organic cyclic compoundGO:00140702040.016
response to growth factorGO:00708482050.016
protein dna complex subunit organizationGO:0071824800.016
response to biotic stimulusGO:00096072760.016
rna processingGO:00063962550.016
regulation of cellular component biogenesisGO:00440872810.016
negative regulation of intracellular signal transductionGO:19025321830.016
regulation of cellular amine metabolic processGO:0033238110.015
gtp metabolic processGO:00460392390.015
mitochondrion organizationGO:00070051560.015
membrane organizationGO:00610242920.015
regulation of secretion by cellGO:19035301770.015
regulation of protein localizationGO:00328802960.015
chromatin silencingGO:0006342120.015
hemopoiesisGO:00300971800.015
regulation of multi organism processGO:00439001570.015
negative regulation of cell cycle phase transitionGO:1901988890.015
nucleus localizationGO:005164710.015
maintenance of locationGO:00512351120.014
dephosphorylationGO:00163112090.014
regulation of cell cycle phase transitionGO:19019871260.014
deoxyribonucleotide metabolic processGO:000926260.014
chemical homeostasisGO:00488783060.014
cellular macromolecular complex assemblyGO:00346223240.014
cilium organizationGO:0044782680.014
centrosome cycleGO:0007098320.014
nucleus organizationGO:0006997280.013
mitotic sister chromatid segregationGO:0000070530.013
organonitrogen compound biosynthetic processGO:19015662000.013
positive regulation of cell activationGO:0050867810.013
gene conversionGO:003582210.013
negative regulation of cell deathGO:00605483450.013
response to organophosphorusGO:0046683410.013
cell activationGO:00017752130.013
dna integrity checkpointGO:0031570710.013
agingGO:0007568660.013
neuron developmentGO:00486661130.013
multi organism reproductive processGO:0044703540.013
single organism cellular localizationGO:19025803320.013
dna strand elongation involved in dna replicationGO:000627130.013
Yeast
regulation of immune responseGO:00507762010.012
nucleosome organizationGO:0034728660.012
autophagyGO:0006914880.012
regulation of protein transportGO:00512232130.012
negative regulation of apoptotic processGO:00430663160.012
amine metabolic processGO:0009308440.012
histone methylationGO:0016571600.012
cell cycle g1 s phase transitionGO:0044843800.012
response to nitrogen compoundGO:19016981840.012
cell developmentGO:00484683280.012
endocytosisGO:00068971590.012
Worm
organelle assemblyGO:00709251760.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
positive regulation of cellular component movementGO:00512721810.012
convergent extensionGO:006002610.012
positive regulation of developmental processGO:00510943140.011
translesion synthesisGO:001998580.011
regulation of mapk cascadeGO:00434082620.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
protein localization to organelleGO:00333652800.011
gene silencingGO:0016458490.011
growthGO:00400072020.011
macromolecule methylationGO:0043414970.011
protein localization to nucleusGO:00345041360.011
carbohydrate derivative biosynthetic processGO:19011372070.011
response to transforming growth factor betaGO:0071559940.011
regulation of energy homeostasisGO:200050510.011
positive regulation of cell cycle processGO:00900681060.011
negative regulation of phosphorus metabolic processGO:00105632670.011
lagging strand elongationGO:000627330.011
Yeast
maintenance of protein location in cellGO:0032507560.011
pharynx developmentGO:006046510.011
dna dependent dna replication maintenance of fidelityGO:0045005140.010
nucleotide biosynthetic processGO:00091651090.010
leukocyte activationGO:00453211640.010
spindle assemblyGO:0051225290.010
2 deoxyribonucleotide metabolic processGO:000939460.010
eye developmentGO:0001654420.010
regulation of microtubule cytoskeleton organizationGO:0070507610.010
cellular component assembly involved in morphogenesisGO:0010927730.010
alpha amino acid metabolic processGO:1901605720.010

LIG1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.117
disease of cellular proliferationDOID:145661740.117
organ system cancerDOID:00506861640.106
gastrointestinal system cancerDOID:3119520.058
large intestine cancerDOID:5672290.015
intestinal cancerDOID:10155290.015
colorectal cancerDOID:9256290.015
musculoskeletal system diseaseDOID:172230.011