Homo sapiens

139 known processes

KLHL22

kelch-like 22 (Drosophila)

(Aliases: KELCHL)

KLHL22 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent protein catabolic processGO:00199412090.069
post embryonic developmentGO:000979120.066
proteolysis involved in cellular protein catabolic processGO:00516032440.064
cellular amino acid metabolic processGO:00065201160.064
amine metabolic processGO:0009308440.063
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.056
cellular ketone metabolic processGO:0042180800.056
cellular macromolecule catabolic processGO:00442653800.053
regulation of cellular amino acid metabolic processGO:000652160.052
protein modification by small protein conjugationGO:00324463420.050
proteasomal protein catabolic processGO:00104981760.048
protein ubiquitinationGO:00165673140.047
protein catabolic processGO:00301633250.046
cellular amine metabolic processGO:0044106410.046
regulation of cellular ketone metabolic processGO:0010565500.044
regulation of proteolysisGO:00301622930.044
negative regulation of protein metabolic processGO:00512483910.042
regulation of cellular amine metabolic processGO:0033238110.042
female gamete generationGO:000729220.040
regulation of cell cycleGO:00517263930.039
positive regulation of cellular amino acid metabolic processGO:004576430.038
cellular protein catabolic processGO:00442572610.037
positive regulation of cellular amine metabolic processGO:003324070.037
purine ribonucleoside metabolic processGO:00461284370.037
ribonucleotide catabolic processGO:00092614050.037
multicellular organismal agingGO:001025930.036
ras protein signal transductionGO:0007265730.035
purine nucleotide catabolic processGO:00061954050.035
negative regulation of cellular protein metabolic processGO:00322693530.035
transmembrane transportGO:00550853990.033
cytoplasmic transportGO:00164823790.033
protein processingGO:00164852260.032
cellular response to dna damage stimulusGO:00069743790.032
modification dependent macromolecule catabolic processGO:00436322120.032
small gtpase mediated signal transductionGO:0007264780.031
purine nucleoside catabolic processGO:00061523980.031
oogenesisGO:004847720.031
ubiquitin dependent protein catabolic processGO:00065112060.031
purine ribonucleotide catabolic processGO:00091544040.030
nucleoside phosphate catabolic processGO:19012924120.030
protein polyubiquitinationGO:00002091100.030
protein maturationGO:00516042330.030
positive regulation of transportGO:00510503360.030
regulation of purine nucleotide metabolic processGO:19005422640.029
purine ribonucleoside catabolic processGO:00461303980.029
immune responseGO:00069553070.029
determination of adult lifespanGO:000834020.029
glycosyl compound catabolic processGO:19016584130.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
cell morphogenesisGO:00009022960.029
regulation of kinase activityGO:00435493140.028
biological adhesionGO:00226103310.028
organophosphate catabolic processGO:00464344300.028
nucleotide catabolic processGO:00091664080.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
cell adhesionGO:00071553250.028
regulation of cell cycle processGO:00105642660.027
positive regulation of hydrolase activityGO:00513453310.027
nucleoside triphosphate metabolic processGO:00091414220.027
mitotic cell cycleGO:00002783260.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
purine containing compound catabolic processGO:00725234110.027
nucleoside catabolic processGO:00091644080.027
ribonucleoside catabolic processGO:00424544060.027
negative regulation of protein processingGO:00109551420.027
regulation of transferase activityGO:00513383550.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
positive regulation of phosphorylationGO:00423273940.026
negative regulation of proteolysisGO:00458611320.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
negative regulation of protein modification processGO:00314002000.026
positive regulation of cellular component organizationGO:00511303760.026
regulation of locomotionGO:00400123290.026
neuromuscular junction developmentGO:000752830.026
regulation of protein catabolic processGO:00421761550.026
lipid metabolic processGO:00066293810.026
regulation of nucleotide metabolic processGO:00061402690.026
negative regulation of cell deathGO:00605483450.025
regulation of protein processingGO:00706131500.025
nucleoside triphosphate catabolic processGO:00091433940.025
single organism cellular localizationGO:19025803320.025
regulation of cell differentiationGO:00455953930.024
mitotic cell cycle processGO:19030472860.024
positive regulation of catabolic processGO:00098963100.024
regulation of anatomical structure morphogenesisGO:00226032860.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
negative regulation of phosphorus metabolic processGO:00105632670.024
negative regulation of catalytic activityGO:00430863350.024
positive regulation of purine nucleotide metabolic processGO:19005442270.023
regulation of protein kinase activityGO:00458592890.023
rho protein signal transductionGO:0007266260.023
neuroblast proliferationGO:000740540.023
negative regulation of phosphate metabolic processGO:00459362670.023
segmentationGO:003528240.022
locomotory behaviorGO:000762610.022
cellular response to endogenous stimulusGO:00714953360.022
guanosine containing compound catabolic processGO:19010692390.022
protein localization to organelleGO:00333652800.022
cellular response to oxygen containing compoundGO:19017012760.022
cell projection organizationGO:00300302520.022
regulation of mapk cascadeGO:00434082620.022
positive regulation of nucleotide metabolic processGO:00459812300.022
signal transduction by phosphorylationGO:00230142970.022
defense responseGO:00069523150.022
regulation of cellular response to stressGO:00801352440.021
positive regulation of cellular catabolic processGO:00313312840.021
cellular component morphogenesisGO:00329893140.021
response to abiotic stimulusGO:00096283360.021
membrane organizationGO:00610242920.021
nervous system developmentGO:00073992930.021
innate immune responseGO:00450871780.021
positive regulation of cell proliferationGO:00082843010.021
gtp catabolic processGO:00061842370.021
negative regulation of cell proliferationGO:00082852280.020
chromatin modificationGO:00165682980.020
positive regulation of protein phosphorylationGO:00019343130.020
regulation of purine nucleotide catabolic processGO:00331212050.020
regulation of cellular component movementGO:00512703340.020
negative regulation of cell cycleGO:00457861930.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
chemical homeostasisGO:00488783060.020
memoryGO:000761330.020
regulation of protein transportGO:00512232130.020
intracellular protein transportGO:00068862700.020
response to oxygen containing compoundGO:19017003690.019
regulation of cell migrationGO:00303342890.019
cellular lipid metabolic processGO:00442553030.019
oxidation reduction processGO:00551143960.019
vesicle mediated transportGO:00161923710.019
cell divisionGO:00513011680.019
regulation of mitotic cell cycleGO:00073461890.019
actin filament based processGO:00300292240.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.019
regulation of nucleoside metabolic processGO:00091182090.019
regulation of nucleotide catabolic processGO:00308112050.019
regenerationGO:003109940.019
carbohydrate derivative biosynthetic processGO:19011372070.019
positive regulation of apoptotic processGO:00430652460.019
negative regulation of apoptotic processGO:00430663160.019
regulation of protein localizationGO:00328802960.019
positive regulation of nucleoside metabolic processGO:00459791860.018
positive regulation of transferase activityGO:00513472270.018
guanosine containing compound metabolic processGO:19010682440.018
regulation of cell motilityGO:20001452990.018
positive regulation of nucleotide catabolic processGO:00308131850.018
single organism carbohydrate metabolic processGO:00447231930.018
dephosphorylationGO:00163112090.018
mapk cascadeGO:00001652880.018
response to cytokineGO:00340972320.018
covalent chromatin modificationGO:00165692540.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
negative regulation of programmed cell deathGO:00430693210.018
carbohydrate metabolic processGO:00059752070.018
cytokinesisGO:0000910960.018
rab protein signal transductionGO:003248240.018
anion transportGO:00068201610.018
positive regulation of gtpase activityGO:00435471660.018
oocyte developmentGO:004859910.018
hindbrain developmentGO:003090230.018
apoptotic signaling pathwayGO:00971902680.018
negative regulation of intracellular signal transductionGO:19025321830.018
positive regulation of programmed cell deathGO:00430682490.018
blastoderm segmentationGO:000735020.018
organonitrogen compound biosynthetic processGO:19015662000.017
microtubule based processGO:00070172100.017
ion transmembrane transportGO:00342203380.017
negative regulation of hydrolase activityGO:00513461820.017
regulation of neural precursor cell proliferationGO:200017740.017
establishment of protein localization to organelleGO:00725941720.017
spermatid differentiationGO:004851540.017
regulation of intracellular transportGO:00323861950.017
regulation of establishment of protein localizationGO:00702012420.017
endosomal transportGO:00161971290.017
peripheral nervous system developmentGO:000742220.017
morphogenesis of embryonic epitheliumGO:001633140.017
negative regulation of catabolic processGO:00098951040.017
negative regulation of cellular component organizationGO:00511292350.017
negative regulation of multicellular organismal processGO:00512413170.017
positive regulation of cell deathGO:00109422630.017
single organism membrane organizationGO:00448022680.017
response to external biotic stimulusGO:00432072610.017
regulation of multi organism processGO:00439001570.017
negative regulation of cellular catabolic processGO:0031330830.016
regulation of response to external stimulusGO:00321012220.016
gtp metabolic processGO:00460392390.016
anterior posterior axis specificationGO:000994820.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of gtp catabolic processGO:00331241800.016
chromatin organizationGO:00063253510.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.016
oocyte differentiationGO:000999420.016
neurogenesisGO:00220081690.016
protein targetingGO:00066051870.016
endomembrane system organizationGO:00102561960.016
small molecule biosynthetic processGO:00442831570.016
protein localization to nucleusGO:00345041360.016
regulation of cell adhesionGO:00301551660.016
response to biotic stimulusGO:00096072760.015
negative regulation of transportGO:00510511760.015
negative regulation of cellular amine metabolic processGO:003323930.015
compound eye developmentGO:004874910.015
positive regulation of kinase activityGO:00336742040.015
cell developmentGO:00484683280.015
cellular macromolecular complex assemblyGO:00346223240.015
cytokine productionGO:00018162470.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
regulation of ras protein signal transductionGO:00465781550.015
negative regulation of phosphorylationGO:00423261740.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
lipid biosynthetic processGO:00086101770.015
response to other organismGO:00517072610.015
regulation of apoptotic signaling pathwayGO:20012331750.015
positive regulation of protein kinase activityGO:00458601900.015
cation transmembrane transportGO:00986552380.015
monocarboxylic acid metabolic processGO:00327871850.015
negative regulation of developmental processGO:00510932470.015
organophosphate biosynthetic processGO:00904071630.015
system processGO:00030083490.015
positive regulation of gtp catabolic processGO:00331261660.015
adult locomotory behaviorGO:000834410.014
regulation of cellular protein catabolic processGO:1903362960.014
positive regulation of developmental processGO:00510943140.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
secretionGO:00469032540.014
glycoprotein metabolic processGO:00091001100.014
spermatid developmentGO:000728640.014
mitotic cell cycle phase transitionGO:00447721620.014
microtubule cytoskeleton organizationGO:00002261760.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
regulation of immune responseGO:00507762010.014
regulation of microtubule based processGO:0032886740.014
maintenance of locationGO:00512351120.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of gtpase activityGO:00430871800.014
protein oligomerizationGO:00512591730.014
organic hydroxy compound metabolic processGO:19016151470.014
histone modificationGO:00165702510.014
ion homeostasisGO:00508012300.014
dna repairGO:00062811980.014
metencephalon developmentGO:002203720.014
neurotransmitter secretionGO:000726940.014
cellular response to cytokine stimulusGO:00713451810.014
cation transportGO:00068123310.013
regulation of cell morphogenesisGO:00226041530.013
regulation of intracellular protein transportGO:00331571230.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
metal ion transportGO:00300012720.013
regulation of cytoplasmic transportGO:19036491490.013
embryonic epithelial tube formationGO:000183840.013
response to organic cyclic compoundGO:00140702040.013
response to organonitrogen compoundGO:00102431560.013
positive regulation of cellular component movementGO:00512721810.013
organelle assemblyGO:00709251760.013
regulation of cytokine productionGO:00018172320.013
organic anion transportGO:00157111030.013
positive regulation of cellular component biogenesisGO:00440891580.013
cellular protein complex assemblyGO:00436231880.013
protein importGO:00170381300.013
protein localization to membraneGO:00726571600.013
positive regulation of cell migrationGO:00303351720.013
cell growthGO:00160491600.013
single organism cell adhesionGO:00986021790.013
response to growth factorGO:00708482050.013
cell projection assemblyGO:00300311260.013
negative regulation of protein maturationGO:19033181420.013
regulation of endopeptidase activityGO:00525481700.013
inorganic ion transmembrane transportGO:00986602310.013
regulation of ras gtpase activityGO:00323181280.013
regulation of protein maturationGO:19033171500.013
growthGO:00400072020.013
response to lipidGO:00339932060.013
negative regulation of locomotionGO:00400131180.013
regulation of cell growthGO:00015581350.013
regulation of protein serine threonine kinase activityGO:00719001790.013
interspecies interaction between organismsGO:00444191560.013
nuclear transportGO:00511691790.013
cellular response to organonitrogen compoundGO:00714171240.013
wnt signaling pathwayGO:00160551560.013
regulation of protein ubiquitinationGO:0031396950.013
regulation of synaptic plasticityGO:004816730.013
cell part morphogenesisGO:00329901370.013
reactive oxygen species metabolic processGO:0072593750.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
cellular response to nitrogen compoundGO:19016991440.012
nucleocytoplasmic transportGO:00069131760.012
nucleoside monophosphate metabolic processGO:00091231910.012
negative regulation of cell migrationGO:00303361020.012
response to nitrogen compoundGO:19016981840.012
endocytosisGO:00068971590.012
regulation of defense responseGO:00313471540.012
organ formationGO:004864530.012
cell cycle phase transitionGO:00447701730.012
atp metabolic processGO:00460341760.012
rhythmic behaviorGO:000762220.012
regulation of dna metabolic processGO:00510521530.012
regulation of growthGO:00400081650.012
cell fate determinationGO:000170930.012
negative regulation of protein catabolic processGO:0042177590.012
epithelium developmentGO:00604292270.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
sulfur compound metabolic processGO:00067901010.012
cerebellum developmentGO:002154920.012
negative regulation of transferase activityGO:00513481240.012
negative regulation of cell differentiationGO:00455961710.012
positive regulation of locomotionGO:00400171860.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
nuclear importGO:00511701060.012
regulation of secretion by cellGO:19035301770.012
secretion by cellGO:00329402260.012
reactive oxygen species biosynthetic processGO:190340940.012
positive regulation of cell differentiationGO:00455972110.012
regulation of peptidase activityGO:00525471800.012
cellular response to growth factor stimulusGO:00713631970.012
i kappab kinase nf kappab signalingGO:00072491660.012
cellular chemical homeostasisGO:00550821800.012
cation homeostasisGO:00550801890.012
multi organism cellular processGO:00447641560.012
response to fungusGO:000962040.012
inorganic cation transmembrane transportGO:00986621940.012
regulation of cell cycle phase transitionGO:19019871260.011
glycoprotein biosynthetic processGO:0009101910.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
positive regulation of immune system processGO:00026842830.011
negative regulation of organelle organizationGO:00106391260.011
epithelium migrationGO:00901321190.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
negative regulation of cell motilityGO:20001461040.011
epithelial cell proliferationGO:00506731280.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
cell projection morphogenesisGO:00488581290.011
defense response to other organismGO:00985421290.011
cardiovascular system developmentGO:00723582620.011
neurological system processGO:00508771630.011
positive regulation of organelle organizationGO:00106381950.011
regulation of cell developmentGO:00602841610.011
regulation of secretionGO:00510461940.011
motor neuron axon guidanceGO:000804520.011
tripartite regional subdivisionGO:000735120.011
response to hormoneGO:00097251750.011
positive regulation of cell cycleGO:00457871400.011
peptidyl tyrosine phosphorylationGO:00181081700.011
circulatory system developmentGO:00723592620.011
plasma membrane organizationGO:00070091150.011
response to radiationGO:00093141510.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
protein autophosphorylationGO:00467771230.011
regulation of cytoskeleton organizationGO:00514931770.011
central nervous system developmentGO:00074171230.011
generation of neuronsGO:00486991520.011
regulation of meiotic cell cycleGO:005144540.011
organelle fissionGO:00482851490.011
tissue migrationGO:00901301190.011
regulation of vesicle mediated transportGO:00606271300.011
positive regulation of ras gtpase activityGO:00323201170.011
negative regulation of cellular component movementGO:00512711060.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
syncytium formation by plasma membrane fusionGO:000076820.011
positive regulation of secretionGO:00510471160.011
negative regulation of multi organism processGO:0043901920.011
inner ear morphogenesisGO:004247240.011
neural tube formationGO:000184130.011
spinal cord developmentGO:002151040.011
peptidyl tyrosine modificationGO:00182121700.011
regulation of cell projection organizationGO:00313441070.011
cell activationGO:00017752130.011
positive regulation of proteolysisGO:00458621420.011
positive regulation of cytokine productionGO:00018191670.011
organic acid biosynthetic processGO:0016053970.011
sensory perception of painGO:001923340.011
protein modification by small protein removalGO:0070646920.011
cellular homeostasisGO:00197251960.011
cell substrate adhesionGO:00315891320.011
reactive nitrogen species metabolic processGO:200105730.011
immune effector processGO:00022521590.011
negative regulation of protein phosphorylationGO:00019331400.010
positive regulation of mapk cascadeGO:00434101900.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
regulation of nucleocytoplasmic transportGO:0046822980.010
single organismal cell cell adhesionGO:00163371480.010
meiosis iGO:000712740.010
peptidyl lysine modificationGO:00182051440.010
viral processGO:00160321460.010
actin cytoskeleton organizationGO:00300362070.010
matingGO:000761810.010
tissue regenerationGO:004224630.010
negative regulation of protein kinase activityGO:0006469980.010
anterior posterior axis specification embryoGO:000859520.010
limbic system developmentGO:002176130.010
positive regulation of protein transportGO:00512221350.010
regulation of bindingGO:00510981110.010
cellular cation homeostasisGO:00300031630.010
negative regulation of cell cycle processGO:00109481210.010
calcium ion transportGO:00068161470.010
meiotic chromosome segregationGO:004513240.010
peptidyl serine phosphorylationGO:00181051010.010
nitrogen compound transportGO:00717051910.010
carboxylic acid biosynthetic processGO:0046394970.010

KLHL22 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.032
musculoskeletal system diseaseDOID:172230.028
inherited metabolic disorderDOID:6552420.023
nervous system diseaseDOID:8634310.020
sensory system diseaseDOID:00501552030.020
central nervous system diseaseDOID:3311860.018
eye and adnexa diseaseDOID:14921500.016
disease of cellular proliferationDOID:145661740.015
eye diseaseDOID:56141490.015
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
muscular diseaseDOID:00800001140.014
retinal diseaseDOID:56791180.013
muscle tissue diseaseDOID:661130.013
myopathyDOID:4231040.012
brain diseaseDOID:936730.011
neurodegenerative diseaseDOID:12891020.011
connective tissue diseaseDOID:651090.010