Homo sapiens

45 known processes

PALB2

partner and localizer of BRCA2

(Aliases: PNCA3,DKFZp686E1054,FLJ21816,DKFZp667I166,FANCN)

PALB2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via homologous recombinationGO:0000724500.952
recombinational repairGO:0000725500.881
specification of axis polarityGO:006500110.830
dna recombinationGO:0006310770.788
male meiosisGO:000714010.729
cellular response to dna damage stimulusGO:00069743790.710
oogenesisGO:004847720.673
anterior posterior axis specificationGO:000994820.621
double strand break repairGO:00063021010.595
dna repairGO:00062811980.494
oocyte maturationGO:000155610.462
regulation of double strand break repair via homologous recombinationGO:0010569110.451
regulation of double strand break repairGO:2000779220.404
female gamete generationGO:000729220.391
intracellular mrna localizationGO:000829810.281
meiotic chromosome segregationGO:004513240.252
response to radiationGO:00093141510.196
chromatin modificationGO:00165682980.157
double strand break repair via single strand annealingGO:004500240.146
microtubule organizing center organizationGO:0031023620.141
cellular macromolecule catabolic processGO:00442653800.117
reciprocal dna recombinationGO:003582540.113
organelle fissionGO:00482851490.113
negative regulation of programmed cell deathGO:00430693210.100
microtubule cytoskeleton organizationGO:00002261760.097
regulation of dna metabolic processGO:00510521530.091
response to ionizing radiationGO:0010212650.089
telomere maintenance via recombinationGO:000072240.079
protein homooligomerizationGO:00512601000.079
dna replicationGO:00062601160.078
glycosyl compound catabolic processGO:19016584130.073
internal protein amino acid acetylationGO:00064751010.072
oocyte developmentGO:004859910.071
cell developmentGO:00484683280.071
sister chromatid segregationGO:0000819540.071
post embryonic developmentGO:000979120.071
negative regulation of apoptotic processGO:00430663160.067
histone modificationGO:00165702510.065
cellular amino acid metabolic processGO:00065201160.061
reciprocal meiotic recombinationGO:000713140.060
purine ribonucleoside triphosphate catabolic processGO:00092073910.059
histone acetylationGO:0016573930.058
nuclear divisionGO:00002801280.058
response to nitrogen compoundGO:19016981840.056
meiosis iGO:000712740.054
regulation of cell cycleGO:00517263930.053
immune system developmentGO:00025201950.050
ribonucleoside monophosphate metabolic processGO:00091611870.050
rna localizationGO:0006403410.047
dna duplex unwindingGO:0032508300.047
single organism reproductive processGO:0044702980.046
reproductive processGO:00224141060.046
pattern specification processGO:0007389430.044
nucleotide catabolic processGO:00091664080.044
negative regulation of cell deathGO:00605483450.043
purine ribonucleoside catabolic processGO:00461303980.043
positive regulation of cellular amino acid metabolic processGO:004576430.043
small gtpase mediated signal transductionGO:0007264780.043
response to abiotic stimulusGO:00096283360.042
cytokinesisGO:0000910960.041
positive regulation of cellular amine metabolic processGO:003324070.040
negative regulation of multicellular organismal processGO:00512413170.040
spermatid developmentGO:000728640.040
dna damage induced protein phosphorylationGO:000697550.039
microtubule based processGO:00070172100.038
growthGO:00400072020.037
intrinsic apoptotic signaling pathwayGO:00971931270.036
ras protein signal transductionGO:0007265730.036
oocyte differentiationGO:000999420.036
purine nucleoside triphosphate catabolic processGO:00091463920.035
negative regulation of protein maturationGO:19033181420.035
ribonucleotide catabolic processGO:00092614050.035
negative regulation of mammary gland epithelial cell proliferationGO:003360030.033
regulation of establishment of protein localizationGO:00702012420.033
cytokine productionGO:00018162470.032
cellular response to abiotic stimulusGO:00712141170.032
purine nucleotide catabolic processGO:00061954050.032
negative regulation of developmental processGO:00510932470.032
cell morphogenesisGO:00009022960.030
response to light stimulusGO:0009416870.030
regulation of mitotic cell cycleGO:00073461890.030
cellular macromolecular complex assemblyGO:00346223240.030
covalent chromatin modificationGO:00165692540.029
dna dependent dna replicationGO:0006261440.029
mitotic sister chromatid segregationGO:0000070530.029
chromatin organizationGO:00063253510.029
amine metabolic processGO:0009308440.029
regulation of dna repairGO:0006282470.029
lipid metabolic processGO:00066293810.028
response to inorganic substanceGO:00100351270.028
negative regulation of protein modification processGO:00314002000.028
histone h3 acetylationGO:0043966450.027
determination of adult lifespanGO:000834020.027
hematopoietic or lymphoid organ developmentGO:00485341860.027
ribonucleoside catabolic processGO:00424544060.027
negative regulation of protein metabolic processGO:00512483910.027
purine nucleoside monophosphate metabolic processGO:00091261860.025
apoptotic signaling pathwayGO:00971902680.025
negative regulation of cell proliferationGO:00082852280.025
negative regulation of protein processingGO:00109551420.024
chromosome segregationGO:00070591140.024
regulation of protein processingGO:00706131500.024
nucleoside triphosphate catabolic processGO:00091433940.024
response to caffeineGO:003100030.024
dna catabolic process endonucleolyticGO:0000737370.024
regulation of endopeptidase activityGO:00525481700.024
cellular ketone metabolic processGO:0042180800.024
positive regulation of cytokine productionGO:00018191670.024
vesicle mediated transportGO:00161923710.024
protein maturationGO:00516042330.024
regulation of cytokine productionGO:00018172320.024
centrosome organizationGO:0051297580.023
nucleoside monophosphate catabolic processGO:00091251590.023
nucleoside triphosphate metabolic processGO:00091414220.023
cellular response to ionizing radiationGO:0071479320.023
regulation of protein maturationGO:19033171500.023
response to cytokineGO:00340972320.022
response to organic cyclic compoundGO:00140702040.022
negative regulation of cellular component organizationGO:00511292350.022
regionalizationGO:0003002290.022
hemopoiesisGO:00300971800.021
mitotic cell cycle phase transitionGO:00447721620.021
nucleoside phosphate catabolic processGO:19012924120.021
ncrna processingGO:0034470830.021
regulation of response to external stimulusGO:00321012220.020
cellular amine metabolic processGO:0044106410.020
epithelium developmentGO:00604292270.020
response to oxygen containing compoundGO:19017003690.020
regulation of cell cycle g2 m phase transitionGO:1902749220.020
protein acylationGO:00435431380.020
peptidyl lysine modificationGO:00182051440.020
g2 dna damage checkpointGO:0031572260.019
regulation of cellular component movementGO:00512703340.019
regulation of cellular ketone metabolic processGO:0010565500.019
regulation of dna recombinationGO:0000018230.019
internal peptidyl lysine acetylationGO:0018393970.019
cellular response to radiationGO:0071478650.019
defense responseGO:00069523150.019
intracellular protein transportGO:00068862700.019
mitotic cell cycle processGO:19030472860.019
protein localization to organelleGO:00333652800.018
negative regulation of hydrolase activityGO:00513461820.018
cell divisionGO:00513011680.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
endocytosisGO:00068971590.018
nervous system developmentGO:00073992930.017
negative regulation of cell cycleGO:00457861930.017
blastocyst developmentGO:000182430.017
multicellular organism reproductionGO:0032504420.017
regulation of protein stabilityGO:0031647870.017
regulation of cellular amine metabolic processGO:0033238110.017
purine ribonucleotide catabolic processGO:00091544040.017
positive regulation of developmental processGO:00510943140.016
signal transduction by phosphorylationGO:00230142970.016
gland developmentGO:0048732480.016
response to metal ionGO:0010038840.016
cell growthGO:00160491600.016
regulation of intracellular transportGO:00323861950.016
positive regulation of cell cycleGO:00457871400.016
cellular response to nitrogen compoundGO:19016991440.016
sister chromatid cohesionGO:0007062240.016
dna packagingGO:0006323770.016
regulation of cell growthGO:00015581350.015
multi organism reproductive processGO:0044703540.015
purine containing compound catabolic processGO:00725234110.015
positive regulation of transportGO:00510503360.015
response to uvGO:0009411730.015
cell cycle checkpointGO:00000751170.015
chemical homeostasisGO:00488783060.015
regulation of protein modification by small protein conjugation or removalGO:19033201070.015
actin mediated cell contractionGO:0070252120.015
cellular response to cytokine stimulusGO:00713451810.014
axis specificationGO:0009798120.014
innate immune responseGO:00450871780.014
lens development in camera type eyeGO:000208820.014
compound eye developmentGO:004874910.014
multicellular organismal reproductive processGO:0048609400.014
oxidation reduction processGO:00551143960.014
rna processingGO:00063962550.014
positive regulation of programmed cell deathGO:00430682490.014
dna geometric changeGO:0032392320.014
meiotic cell cycleGO:0051321130.014
dna damage checkpointGO:0000077680.013
positive regulation of cellular component organizationGO:00511303760.013
atp catabolic processGO:00062001570.013
immune responseGO:00069553070.013
head developmentGO:00603221080.013
positive regulation of cell deathGO:00109422630.013
rna catabolic processGO:0006401710.013
reproductionGO:0000003630.013
regulation of protein kinase activityGO:00458592890.013
regulation of dna replicationGO:0006275680.013
regulation of protein transportGO:00512232130.013
dna integrity checkpointGO:0031570710.013
purine nucleoside catabolic processGO:00061523980.013
purine ribonucleoside metabolic processGO:00461284370.013
cellular component morphogenesisGO:00329893140.013
nucleoside monophosphate metabolic processGO:00091231910.013
negative regulation of catalytic activityGO:00430863350.013
response to purine containing compoundGO:0014074400.013
protein oligomerizationGO:00512591730.013
negative regulation of cellular catabolic processGO:0031330830.013
regulation of locomotionGO:00400123290.013
cellular response to endogenous stimulusGO:00714953360.013
regulation of protein catabolic processGO:00421761550.013
regulation of mammary gland epithelial cell proliferationGO:003359960.012
negative regulation of proteolysisGO:00458611320.012
positive regulation of cellular catabolic processGO:00313312840.012
negative regulation of dna metabolic processGO:0051053570.012
organophosphate catabolic processGO:00464344300.012
regulation of growthGO:00400081650.012
cellular response to organonitrogen compoundGO:00714171240.012
gtp catabolic processGO:00061842370.012
hindbrain developmentGO:003090230.012
chromosome separationGO:0051304230.012
cellular protein complex assemblyGO:00436231880.012
ncrna metabolic processGO:00346601080.012
positive regulation of cellular component biogenesisGO:00440891580.012
protein processingGO:00164852260.012
regulation of immune responseGO:00507762010.012
dna double strand break processingGO:0000729100.012
posttranscriptional regulation of gene expressionGO:00106082130.012
response to gamma radiationGO:0010332140.012
regulation of leukocyte activationGO:00026941150.012
nucleocytoplasmic transportGO:00069131760.012
g2 m transition of mitotic cell cycleGO:0000086410.012
dorsal ventral pattern formationGO:0009953150.012
protein glycosylationGO:0006486620.012
regulation of g2 m transition of mitotic cell cycleGO:0010389200.012
protein ubiquitinationGO:00165673140.012
multicellular organismal agingGO:001025930.011
negative regulation of cellular protein metabolic processGO:00322693530.011
positive regulation of catabolic processGO:00098963100.011
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.011
cellular response to oxygen containing compoundGO:19017012760.011
cell projection organizationGO:00300302520.011
negative regulation of cellular protein catabolic processGO:1903363380.011
regulation of mitosisGO:0007088630.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
signal transduction by p53 class mediatorGO:0072331720.011
mitochondrion organizationGO:00070051560.011
regulation of proteasomal protein catabolic processGO:0061136870.011
single organism cellular localizationGO:19025803320.011
positive regulation of cellular component movementGO:00512721810.011
regulation of proteolysisGO:00301622930.011
spermatid differentiationGO:004851540.011
embryonic epithelial tube formationGO:000183840.011
tube closureGO:006060630.011
regulation of protein localizationGO:00328802960.011
regulation of cytoskeleton organizationGO:00514931770.010
cardiac muscle cell contractionGO:008600340.010
positive regulation of cell motilityGO:20001471770.010
regulation of microtubule cytoskeleton organizationGO:0070507610.010
somatic diversification of immunoglobulins involved in immune responseGO:000220830.010
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.010
tube morphogenesisGO:0035239950.010
regulation of kinase activityGO:00435493140.010
maintenance of locationGO:00512351120.010
regulation of cell developmentGO:00602841610.010
positive regulation of hydrolase activityGO:00513453310.010

PALB2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.367
disease of cellular proliferationDOID:145661740.367
endocrine gland cancerDOID:170260.243
organ system cancerDOID:00506861640.243
anemiaDOID:2355550.185
hematopoietic system diseaseDOID:741000.185
immune system diseaseDOID:29141550.185
aplastic anemiaDOID:12449300.086
bone marrow diseaseDOID:4961310.086
thoracic cancerDOID:5093210.078
breast cancerDOID:1612210.078
urinary system cancerDOID:3996150.073
kidney cancerDOID:263110.073
nervous system diseaseDOID:8634310.027
central nervous system diseaseDOID:3311860.027
reproductive organ cancerDOID:193230.022
congenital hypoplastic anemiaDOID:1342260.019
fanconi s anemiaDOID:13636160.019
prostate cancerDOID:10283130.018
male reproductive organ cancerDOID:3856160.018
neurodegenerative diseaseDOID:12891020.012
pancreatic cancerDOID:179380.006