Homo sapiens

19 known processes

CLIC3

chloride intracellular channel 3

CLIC3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.067
post embryonic developmentGO:000979120.065
cellular ketone metabolic processGO:0042180800.063
cellular amine metabolic processGO:0044106410.062
lipid metabolic processGO:00066293810.061
regulation of cellular amino acid metabolic processGO:000652160.058
amine metabolic processGO:0009308440.055
regulation of cellular ketone metabolic processGO:0010565500.053
regulation of cellular amine metabolic processGO:0033238110.051
ribonucleoside catabolic processGO:00424544060.047
purine containing compound catabolic processGO:00725234110.047
negative regulation of protein metabolic processGO:00512483910.046
nucleoside catabolic processGO:00091644080.046
negative regulation of cellular protein metabolic processGO:00322693530.045
purine ribonucleoside catabolic processGO:00461303980.044
actin filament based processGO:00300292240.044
ras protein signal transductionGO:0007265730.044
nucleoside triphosphate metabolic processGO:00091414220.043
purine nucleoside triphosphate metabolic processGO:00091444120.043
defense responseGO:00069523150.042
purine nucleoside catabolic processGO:00061523980.042
biological adhesionGO:00226103310.041
nucleoside phosphate catabolic processGO:19012924120.041
purine ribonucleotide catabolic processGO:00091544040.041
cytoplasmic transportGO:00164823790.041
Human
regulation of cell migrationGO:00303342890.040
vesicle mediated transportGO:00161923710.040
organophosphate catabolic processGO:00464344300.040
multicellular organismal agingGO:001025930.039
glycosyl compound catabolic processGO:19016584130.039
cell adhesionGO:00071553250.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
purine ribonucleoside metabolic processGO:00461284370.039
negative regulation of catalytic activityGO:00430863350.039
determination of adult lifespanGO:000834020.038
ribonucleoside triphosphate catabolic processGO:00092033910.038
membrane organizationGO:00610242920.038
regulation of cellular component movementGO:00512703340.038
ribonucleotide catabolic processGO:00092614050.037
positive regulation of cellular component organizationGO:00511303760.037
positive regulation of hydrolase activityGO:00513453310.037
guanosine containing compound catabolic processGO:19010692390.037
purine nucleoside triphosphate catabolic processGO:00091463920.037
positive regulation of phosphorylationGO:00423273940.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
positive regulation of cellular amine metabolic processGO:003324070.036
protein processingGO:00164852260.036
epidermis morphogenesisGO:004873030.036
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
single organism cellular localizationGO:19025803320.035
small gtpase mediated signal transductionGO:0007264780.035
positive regulation of apoptotic processGO:00430652460.035
regulation of locomotionGO:00400123290.035
ribonucleoside triphosphate metabolic processGO:00091994120.034
positive regulation of nucleotide metabolic processGO:00459812300.034
immune responseGO:00069553070.034
purine nucleotide catabolic processGO:00061954050.034
epithelium developmentGO:00604292270.034
nucleotide catabolic processGO:00091664080.033
nucleoside triphosphate catabolic processGO:00091433940.033
positive regulation of cell deathGO:00109422630.033
regulation of protein localizationGO:00328802960.033
negative regulation of multicellular organismal processGO:00512413170.033
cellular lipid metabolic processGO:00442553030.033
endomembrane system organizationGO:00102561960.032
response to lipidGO:00339932060.032
regulation of cellular component biogenesisGO:00440872810.032
regulation of cell differentiationGO:00455953930.031
rho protein signal transductionGO:0007266260.031
response to oxygen containing compoundGO:19017003690.030
single organismal cell cell adhesionGO:00163371480.030
oogenesisGO:004847720.030
negative regulation of programmed cell deathGO:00430693210.030
regulation of nucleotide metabolic processGO:00061402690.030
female gamete generationGO:000729220.029
positive regulation of catabolic processGO:00098963100.029
small molecule biosynthetic processGO:00442831570.029
regulation of anatomical structure morphogenesisGO:00226032860.029
secretion by cellGO:00329402260.029
positive regulation of programmed cell deathGO:00430682490.028
regulation of cell motilityGO:20001452990.028
positive regulation of transportGO:00510503360.028
protein maturationGO:00516042330.028
signal transduction by phosphorylationGO:00230142970.028
single organism membrane organizationGO:00448022680.028
negative regulation of phosphate metabolic processGO:00459362670.028
negative regulation of phosphorus metabolic processGO:00105632670.028
regulation of establishment of protein localizationGO:00702012420.027
positive regulation of cellular catabolic processGO:00313312840.027
response to organic cyclic compoundGO:00140702040.027
cellular macromolecule catabolic processGO:00442653800.027
intracellular protein transportGO:00068862700.027
cellular component morphogenesisGO:00329893140.027
cellular macromolecular complex assemblyGO:00346223240.027
innate immune responseGO:00450871780.027
segmentationGO:003528240.027
apoptotic signaling pathwayGO:00971902680.027
regulation of protein kinase activityGO:00458592890.027
negative regulation of cellular component organizationGO:00511292350.027
regulation of nucleoside metabolic processGO:00091182090.026
positive regulation of immune system processGO:00026842830.026
regulation of purine nucleotide metabolic processGO:19005422640.026
cellular response to endogenous stimulusGO:00714953360.026
regulation of transferase activityGO:00513383550.026
mapk cascadeGO:00001652880.026
cytokine productionGO:00018162470.026
negative regulation of apoptotic processGO:00430663160.026
enzyme linked receptor protein signaling pathwayGO:00071673030.025
protein localization to organelleGO:00333652800.025
response to abiotic stimulusGO:00096283360.025
regulation of purine nucleotide catabolic processGO:00331212050.025
locomotory behaviorGO:000762610.025
guanosine containing compound metabolic processGO:19010682440.024
positive regulation of nucleotide catabolic processGO:00308131850.024
cell activationGO:00017752130.024
protein catabolic processGO:00301633250.024
cellular response to dna damage stimulusGO:00069743790.024
actin cytoskeleton organizationGO:00300362070.024
cell projection organizationGO:00300302520.024
positive regulation of protein phosphorylationGO:00019343130.024
regenerationGO:003109940.024
plasma membrane organizationGO:00070091150.024
negative regulation of developmental processGO:00510932470.024
regulation of kinase activityGO:00435493140.024
single organism cell adhesionGO:00986021790.024
skin developmentGO:0043588760.023
response to woundingGO:00096111680.023
regulation of cell cycleGO:00517263930.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
establishment of protein localization to membraneGO:00901501210.023
regulation of proteolysisGO:00301622930.023
neuromuscular junction developmentGO:000752830.023
regulation of cytoskeleton organizationGO:00514931770.023
system processGO:00030083490.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
protein localization to membraneGO:00726571600.023
cellular response to oxygen containing compoundGO:19017012760.023
gtp metabolic processGO:00460392390.023
regulation of cell adhesionGO:00301551660.023
regulation of nucleotide catabolic processGO:00308112050.023
negative regulation of cellular amine metabolic processGO:003323930.023
negative regulation of locomotionGO:00400131180.023
positive regulation of cell proliferationGO:00082843010.023
gtp catabolic processGO:00061842370.023
negative regulation of cell motilityGO:20001461040.022
regulation of peptidase activityGO:00525471800.022
positive regulation of organelle organizationGO:00106381950.022
nervous system developmentGO:00073992930.022
secretionGO:00469032540.022
negative regulation of cell deathGO:00605483450.022
regulation of gtp catabolic processGO:00331241800.021
response to other organismGO:00517072610.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
negative regulation of hydrolase activityGO:00513461820.021
maintenance of locationGO:00512351120.021
morphogenesis of embryonic epitheliumGO:001633140.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
negative regulation of protein modification processGO:00314002000.021
regulation of gtpase activityGO:00430871800.021
dephosphorylationGO:00163112090.021
response to external biotic stimulusGO:00432072610.021
response to biotic stimulusGO:00096072760.021
regulation of cell cycle processGO:00105642660.021
regulation of secretion by cellGO:19035301770.021
positive regulation of cell migrationGO:00303351720.020
anterior posterior axis specificationGO:000994820.020
cellular protein complex assemblyGO:00436231880.020
lipid biosynthetic processGO:00086101770.020
positive regulation of gtpase activityGO:00435471660.020
negative regulation of cell migrationGO:00303361020.020
keratinizationGO:003142420.020
negative regulation of phosphorylationGO:00423261740.020
epithelial cell differentiationGO:00308551410.020
regulation of cytokine productionGO:00018172320.020
cell morphogenesisGO:00009022960.020
cardiovascular system developmentGO:00723582620.020
negative regulation of androgen biosynthetic processGO:200018010.019
regulation of cellular response to stressGO:00801352440.019
testosterone biosynthetic processGO:006137020.019
regulation of intracellular transportGO:00323861950.019
Human
muscle system processGO:0003012810.019
cellular protein catabolic processGO:00442572610.019
regulation of secretionGO:00510461940.019
response to growth factorGO:00708482050.019
positive regulation of locomotionGO:00400171860.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
organonitrogen compound biosynthetic processGO:19015662000.019
protein modification by small protein conjugationGO:00324463420.019
memoryGO:000761330.019
sex determinationGO:000753030.019
mitotic cell cycleGO:00002783260.019
epithelial cell migrationGO:00106311190.019
positive regulation of secretionGO:00510471160.019
positive regulation of developmental processGO:00510943140.018
monocarboxylic acid metabolic processGO:00327871850.018
positive regulation of cellular component movementGO:00512721810.018
organelle assemblyGO:00709251760.018
cellular response to growth factor stimulusGO:00713631970.018
striated muscle contractionGO:0006941520.018
forelimb morphogenesisGO:003513640.018
positive regulation of cellular component biogenesisGO:00440891580.018
regulation of protein transportGO:00512232130.018
oocyte differentiationGO:000999420.018
mitotic cell cycle processGO:19030472860.018
organ morphogenesisGO:00098871470.018
rhythmic behaviorGO:000762220.018
hair follicle morphogenesisGO:003106920.018
peripheral nervous system developmentGO:000742220.018
organic acid biosynthetic processGO:0016053970.018
epidermis developmentGO:0008544590.018
blastoderm segmentationGO:000735020.018
carbohydrate derivative biosynthetic processGO:19011372070.018
regulation of small gtpase mediated signal transductionGO:00510561560.018
regulation of endopeptidase activityGO:00525481700.018
protein oligomerizationGO:00512591730.018
regulation of immune responseGO:00507762010.018
positive regulation of gtp catabolic processGO:00331261660.018
embryonic epithelial tube formationGO:000183840.018
response to fungusGO:000962040.018
response to hormoneGO:00097251750.018
negative regulation of cell proliferationGO:00082852280.017
actin filament organizationGO:00070151280.017
positive regulation of nucleoside metabolic processGO:00459791860.017
positive regulation of cell motilityGO:20001471770.017
cation transportGO:00068123310.017
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
nitrogen compound transportGO:00717051910.017
immune system developmentGO:00025201950.017
muscle contractionGO:0006936730.017
regulation of response to external stimulusGO:00321012220.017
transmembrane transportGO:00550853990.017
regulation of dna metabolic processGO:00510521530.017
regulation of actin cytoskeleton organizationGO:00329561160.017
spermatid differentiationGO:004851540.017
carboxylic acid biosynthetic processGO:0046394970.017
circulatory system developmentGO:00723592620.017
anion transportGO:00068201610.017
oocyte developmentGO:004859910.017
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
reactive nitrogen species metabolic processGO:200105730.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
tissue migrationGO:00901301190.017
positive regulation of mapk cascadeGO:00434101900.017
protein ubiquitinationGO:00165673140.016
regulation of ras protein signal transductionGO:00465781550.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of neural precursor cell proliferationGO:200017740.016
regulation of actin filament based processGO:00329701410.016
cell projection assemblyGO:00300311260.016
circadian behaviorGO:004851220.016
epidermal cell differentiationGO:0009913450.016
cell fate determinationGO:000170930.016
carbohydrate metabolic processGO:00059752070.016
matingGO:000761810.016
positive regulation of protein kinase activityGO:00458601900.016
negative regulation of intracellular signal transductionGO:19025321830.016
posttranscriptional regulation of gene expressionGO:00106082130.016
wnt signaling pathwayGO:00160551560.016
anterior posterior axis specification embryoGO:000859520.016
cell divisionGO:00513011680.016
chemical homeostasisGO:00488783060.016
Human
positive regulation of cell differentiationGO:00455972110.016
defense response to fungusGO:005083240.016
regulation of mapk cascadeGO:00434082620.016
oxidative stress induced premature senescenceGO:009040330.016
chromatin organizationGO:00063253510.016
epithelium migrationGO:00901321190.016
neuroblast proliferationGO:000740540.016
protein targetingGO:00066051870.016
organ formationGO:004864530.016
cell developmentGO:00484683280.016
alcohol metabolic processGO:00060661140.016
spermatid developmentGO:000728640.016
regulation of cysteine type endopeptidase activityGO:20001161270.015
regulation of cytoplasmic transportGO:19036491490.015
Human
nucleocytoplasmic transportGO:00069131760.015
regulation of ras gtpase activityGO:00323181280.015
response to inorganic substanceGO:00100351270.015
prostate gland morphogenesisGO:006051210.015
negative regulation of cell cycleGO:00457861930.015
prostate gland developmentGO:003085030.015
calcium ion transportGO:00068161470.015
Human
cardiac muscle contractionGO:0060048340.015
microtubule based processGO:00070172100.015
ion homeostasisGO:00508012300.015
Human
hemopoiesisGO:00300971800.015
regulation of protein processingGO:00706131500.015
tripartite regional subdivisionGO:000735120.015
regulation of protein maturationGO:19033171500.015
metal ion transportGO:00300012720.015
Human
negative regulation of cellular component movementGO:00512711060.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
intrinsic apoptotic signaling pathwayGO:00971931270.015
organic hydroxy compound metabolic processGO:19016151470.015
compound eye developmentGO:004874910.015
angiogenesisGO:00015251470.015
ameboidal type cell migrationGO:00016671350.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
epithelial cell proliferationGO:00506731280.014
negative regulation of cell differentiationGO:00455961710.014
nucleoside monophosphate metabolic processGO:00091231910.014
embryonic forelimb morphogenesisGO:003511540.014
protein localization to plasma membraneGO:0072659930.014
cell growthGO:00160491600.014
regulation of multi organism processGO:00439001570.014
regulation of mitotic cell cycleGO:00073461890.014
fatty acid metabolic processGO:00066311150.014
cellular homeostasisGO:00197251960.014
Human
negative regulation of proteolysisGO:00458611320.014
negative regulation of organelle organizationGO:00106391260.014
androgen biosynthetic processGO:000670230.014
central nervous system developmentGO:00074171230.014
positive regulation of tooth mineralizationGO:007017220.014
positive regulation of transferase activityGO:00513472270.014
glycoprotein metabolic processGO:00091001100.014
single organism carbohydrate metabolic processGO:00447231930.014
sequestering of metal ionGO:0051238240.014
proteasomal protein catabolic processGO:00104981760.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
regulation of vesicle mediated transportGO:00606271300.014
adult locomotory behaviorGO:000834410.014
regulation of protein catabolic processGO:00421761550.014
hindbrain developmentGO:003090230.014
modification dependent macromolecule catabolic processGO:00436322120.014
reactive oxygen species metabolic processGO:0072593750.014
nuclear transportGO:00511691790.014
tongue developmentGO:004358610.014
lung alveolus developmentGO:004828640.014
positive regulation of aldosterone biosynthetic processGO:003234920.014
vasculature developmentGO:00019441810.014
ion transmembrane transportGO:00342203380.014
syncytium formation by plasma membrane fusionGO:000076820.014
ubiquitin dependent protein catabolic processGO:00065112060.014
modification dependent protein catabolic processGO:00199412090.014
positive regulation of aldosterone metabolic processGO:003234620.014
neural tube formationGO:000184130.013
cellular response to toxic substanceGO:009723740.013
positive regulation of kinase activityGO:00336742040.013
positive regulation of proteolysisGO:00458621420.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
positive regulation of immune responseGO:00507781590.013
sensory perception of smellGO:000760820.013
protein autophosphorylationGO:00467771230.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
histone modificationGO:00165702510.013
regulation of cell growthGO:00015581350.013
positive regulation of synaptic transmissionGO:005080640.013
neurotransmitter secretionGO:000726940.013
growthGO:00400072020.013
viral processGO:00160321460.013
canonical wnt signaling pathwayGO:00600701160.013
sequestering of calcium ionGO:0051208170.013
establishment of protein localization to organelleGO:00725941720.013
regulation of apoptotic signaling pathwayGO:20012331750.013
oxidation reduction processGO:00551143960.013
Human
defense response to other organismGO:00985421290.013
microtubule cytoskeleton organizationGO:00002261760.013
salivary gland morphogenesisGO:000743540.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
positive regulation of ras gtpase activityGO:00323201170.013
detection of mechanical stimulusGO:005098240.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
positive regulation of protein transportGO:00512221350.013
establishment of protein localization to plasma membraneGO:0090002680.013
actin mediated cell contractionGO:0070252120.013
blood circulationGO:00080151130.013
immune effector processGO:00022521590.013
endothelial cell migrationGO:0043542860.013
blood vessel developmentGO:00015681720.013
cellular ion homeostasisGO:00068731680.013
Human
negative regulation of transferase activityGO:00513481240.013
chemotaxisGO:00069351570.013
organophosphate biosynthetic processGO:00904071630.013
embryonic hindlimb morphogenesisGO:003511620.013
negative regulation of protein maturationGO:19033181420.013
cation transmembrane transportGO:00986552380.013
Human
response to bacteriumGO:00096171440.013
positive regulation of hormone biosynthetic processGO:004688640.013
response to axon injuryGO:004867810.013
morphogenesis of a polarized epitheliumGO:000173830.013
inorganic ion transmembrane transportGO:00986602310.013
regulation of homeostatic processGO:00328441210.013
Human
copulationGO:000762010.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
negative regulation of protein processingGO:00109551420.013
negative regulation of protein phosphorylationGO:00019331400.013
divalent inorganic cation transportGO:00725111580.013
Human
regulation of response to woundingGO:19030341010.013
regulation of growthGO:00400081650.013
ossificationGO:00015031210.013
motor neuron axon guidanceGO:000804520.012
cardiac muscle cell contractionGO:008600340.012
hindlimb morphogenesisGO:003513720.012
keratinocyte differentiationGO:0030216360.012
response to radiationGO:00093141510.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
interspecies interaction between organismsGO:00444191560.012
tissue regenerationGO:004224630.012
positive regulation of cytokine productionGO:00018191670.012
regulation of cell developmentGO:00602841610.012
zymogen activationGO:0031638700.012
protein acylationGO:00435431380.012
multi organism cellular processGO:00447641560.012
regulation of protein complex assemblyGO:00432541470.012
regulation of cell morphogenesisGO:00226041530.012
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.012
endosomal transportGO:00161971290.012
regulation of wnt signaling pathwayGO:00301111230.012
i kappab kinase nf kappab signalingGO:00072491660.012
mitotic cell cycle phase transitionGO:00447721620.012
regulation of synaptic plasticityGO:004816730.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
cellular response to organic cyclic compoundGO:00714071270.012
head developmentGO:00603221080.012
negative regulation of catabolic processGO:00098951040.012
response to cytokineGO:00340972320.012
nucleoside monophosphate catabolic processGO:00091251590.012
cation homeostasisGO:00550801890.012
Human
photoreceptor cell differentiationGO:004653020.012
inorganic cation transmembrane transportGO:00986621940.012
Human
cellular chemical homeostasisGO:00550821800.012
Human
cell substrate adhesionGO:00315891320.012
tube closureGO:006060630.012
cdc42 protein signal transductionGO:003248840.012
primary neural tube formationGO:001402030.012
cellular metal ion homeostasisGO:00068751460.012
Human
circulatory system processGO:00030131130.012
monocarboxylic acid biosynthetic processGO:0072330670.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of vasculature developmentGO:1901342970.012
protein localization to nucleusGO:00345041360.012
covalent chromatin modificationGO:00165692540.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
protein secretionGO:0009306980.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
leukocyte activationGO:00453211640.012
inner ear morphogenesisGO:004247240.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
pericardium developmentGO:006003920.012
cell proliferation in forebrainGO:002184610.012
response to metal ionGO:0010038840.012
atp catabolic processGO:00062001570.012
positive regulation of secretion by cellGO:19035321080.012
t cell differentiation in thymusGO:003307740.012
sleepGO:003043120.012
negative regulation of cell cycle processGO:00109481210.012
myoblast fusionGO:000752010.011
cell cycle phase transitionGO:00447701730.011
negative regulation of peptidase activityGO:0010466910.011
chromatin modificationGO:00165682980.011
regulation of testosterone biosynthetic processGO:200022420.011
endocytosisGO:00068971590.011
post embryonic organ developmentGO:004856910.011
peptidyl tyrosine modificationGO:00182121700.011
non canonical wnt signaling pathway via mapk cascadeGO:003803040.011
positive regulation of peptidase activityGO:0010952880.011
g protein coupled receptor signaling pathwayGO:00071862070.011
cellular response to abiotic stimulusGO:00712141170.011
stem cell divisionGO:001714520.011
blood vessel morphogenesisGO:00485141620.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
negative regulation of growthGO:0045926970.011
regulation of defense responseGO:00313471540.011
developmental programmed cell deathGO:001062330.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
regulation of cell activationGO:00508651250.011
cellular response to lipidGO:00713961270.011
peptidyl tyrosine phosphorylationGO:00181081700.011
wound healingGO:00420601150.011
thymus developmentGO:004853830.011
rna processingGO:00063962550.011
atp metabolic processGO:00460341760.011

CLIC3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.024
musculoskeletal system diseaseDOID:172230.024
inherited metabolic disorderDOID:6552420.022
nervous system diseaseDOID:8634310.021
sensory system diseaseDOID:00501552030.021
disease of cellular proliferationDOID:145661740.019
central nervous system diseaseDOID:3311860.018
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
cancerDOID:1621670.017
organ system cancerDOID:00506861640.016
connective tissue diseaseDOID:651090.016
immune system diseaseDOID:29141550.016
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014
bone diseaseDOID:0080001880.013
neurodegenerative diseaseDOID:12891020.013
cardiovascular system diseaseDOID:12871060.012
myopathyDOID:4231040.012
retinal diseaseDOID:56791180.012