Homo sapiens

70 known processes

PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

(Aliases: MGC33047,MGC33046,H731)

PDCD4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.364
cell morphogenesisGO:00009022960.124
cell developmentGO:00484683280.120
Fly
cellular macromolecule catabolic processGO:00442653800.120
cellular component morphogenesisGO:00329893140.105
ras protein signal transductionGO:0007265730.098
neurotransmitter gated ion channel clusteringGO:007257810.089
small gtpase mediated signal transductionGO:0007264780.086
cell projection organizationGO:00300302520.073
negative regulation of developmental processGO:00510932470.070
regulation of cell migrationGO:00303342890.069
cellular amine metabolic processGO:0044106410.068
positive regulation of transportGO:00510503360.067
multicellular organismal agingGO:001025930.066
mitotic cell cycle processGO:19030472860.065
positive regulation of catabolic processGO:00098963100.065
negative regulation of cell differentiationGO:00455961710.064
regulation of cellular component movementGO:00512703340.064
negative regulation of multicellular organismal processGO:00512413170.062
rho protein signal transductionGO:0007266260.060
memoryGO:000761330.058
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.058
microtubule based processGO:00070172100.058
negative regulation of catalytic activityGO:00430863350.057
amine metabolic processGO:0009308440.056
cell adhesion molecule productionGO:006035230.055
regulation of small gtpase mediated signal transductionGO:00510561560.055
chemotaxisGO:00069351570.054
regulation of mapk cascadeGO:00434082620.053
lipid localizationGO:00108761060.053
positive regulation of phosphorylationGO:00423273940.052
positive regulation of cellular catabolic processGO:00313312840.052
modification dependent macromolecule catabolic processGO:00436322120.052
cellular lipid metabolic processGO:00442553030.051
cellular ketone metabolic processGO:0042180800.051
protein catabolic processGO:00301633250.050
regulation of cellular ketone metabolic processGO:0010565500.050
negative regulation of phosphate metabolic processGO:00459362670.050
protein localization to membraneGO:00726571600.049
regulation of ras protein signal transductionGO:00465781550.049
positive regulation of immune system processGO:00026842830.048
carbohydrate derivative biosynthetic processGO:19011372070.048
cell projection morphogenesisGO:00488581290.047
regulation of proteolysisGO:00301622930.047
cellular response to dna damage stimulusGO:00069743790.047
positive regulation of proteolysisGO:00458621420.046
maintenance of locationGO:00512351120.045
microtubule cytoskeleton organizationGO:00002261760.045
actin filament based processGO:00300292240.045
cellular protein catabolic processGO:00442572610.044
lipid metabolic processGO:00066293810.043
epithelium developmentGO:00604292270.043
negative regulation of protein metabolic processGO:00512483910.043
cellular amino acid metabolic processGO:00065201160.043
locomotory behaviorGO:000762610.043
system processGO:00030083490.043
organelle assemblyGO:00709251760.043
rna splicingGO:00083801310.042
regulation of locomotionGO:00400123290.041
cellular response to endogenous stimulusGO:00714953360.041
cellular macromolecular complex assemblyGO:00346223240.040
negative regulation of cellular protein metabolic processGO:00322693530.040
cellular homeostasisGO:00197251960.039
regulation of cytoskeleton organizationGO:00514931770.039
regulation of cell differentiationGO:00455953930.038
Fly
positive regulation of ion transportGO:0043270870.038
proteolysis involved in cellular protein catabolic processGO:00516032440.037
cell morphogenesis involved in differentiationGO:00009041440.037
regulation of purine nucleotide metabolic processGO:19005422640.037
rna processingGO:00063962550.037
positive regulation of apoptotic processGO:00430652460.037
negative regulation of cell deathGO:00605483450.037
regulation of sequence specific dna binding transcription factor activityGO:00510902110.036
vesicle mediated transportGO:00161923710.036
positive regulation of purine nucleotide metabolic processGO:19005442270.036
cilium assemblyGO:0042384630.036
nervous system developmentGO:00073992930.036
enzyme linked receptor protein signaling pathwayGO:00071673030.036
cell part morphogenesisGO:00329901370.035
cell cycle phase transitionGO:00447701730.035
single organism membrane organizationGO:00448022680.035
negative regulation of protein modification processGO:00314002000.035
oogenesisGO:004847720.035
Fly
regulation of cell cycle processGO:00105642660.035
modification dependent protein catabolic processGO:00199412090.034
presynaptic membrane organizationGO:009709030.034
organophosphate biosynthetic processGO:00904071630.034
positive regulation of cellular component organizationGO:00511303760.034
reproductive processGO:00224141060.034
Fly
regulation of protein transportGO:00512232130.034
spindle organizationGO:0007051530.034
regulation of protein localizationGO:00328802960.034
mapk cascadeGO:00001652880.033
negative regulation of phosphorus metabolic processGO:00105632670.033
positive regulation of hydrolase activityGO:00513453310.033
positive regulation of organelle organizationGO:00106381950.032
taxisGO:00423301570.032
cyclic nucleotide metabolic processGO:0009187820.032
single organism cellular localizationGO:19025803320.032
regulation of cellular component biogenesisGO:00440872810.032
regulation of protein kinase activityGO:00458592890.032
negative regulation of cell proliferationGO:00082852280.032
signal transduction by phosphorylationGO:00230142970.032
female gamete generationGO:000729220.031
Fly
positive regulation of nucleotide metabolic processGO:00459812300.030
regulation of cell motilityGO:20001452990.030
regulation of mitotic cell cycleGO:00073461890.030
cilium organizationGO:0044782680.030
membrane organizationGO:00610242920.030
determination of adult lifespanGO:000834020.030
ribonucleoside triphosphate metabolic processGO:00091994120.029
mitotic cell cycleGO:00002783260.029
maintenance of location in cellGO:0051651620.029
lipid catabolic processGO:0016042840.028
single organism reproductive processGO:0044702980.028
Fly
mitotic cell cycle phase transitionGO:00447721620.028
regulation of cellular amino acid metabolic processGO:000652160.028
cilium morphogenesisGO:0060271750.028
epithelial cell proliferationGO:00506731280.028
negative regulation of epithelial cell migrationGO:0010633380.028
postsynaptic membrane organizationGO:000194120.028
regulation of transferase activityGO:00513383550.028
actin cytoskeleton organizationGO:00300362070.027
regulation of actin filament based processGO:00329701410.027
positive regulation of developmental processGO:00510943140.027
Fly
negative regulation of cellular component organizationGO:00511292350.027
purine ribonucleotide biosynthetic processGO:0009152790.027
nucleotide catabolic processGO:00091664080.026
glycerophospholipid metabolic processGO:0006650840.026
dna repairGO:00062811980.026
regulation of anatomical structure sizeGO:00900661010.026
protein importGO:00170381300.026
neurogenesisGO:00220081690.026
regulation of map kinase activityGO:00434051080.026
intracellular protein transportGO:00068862700.026
organophosphate catabolic processGO:00464344300.025
epithelial cell differentiationGO:00308551410.025
cell projection assemblyGO:00300311260.025
regulation of establishment of protein localizationGO:00702012420.025
protein localization to organelleGO:00333652800.025
regulation of cholesterol metabolic processGO:009018140.025
positive regulation of cellular amine metabolic processGO:003324070.025
chromatin organizationGO:00063253510.025
response to oxygen containing compoundGO:19017003690.024
regulation of response to woundingGO:19030341010.024
regulation of anatomical structure morphogenesisGO:00226032860.024
purine ribonucleoside metabolic processGO:00461284370.024
posttranscriptional regulation of gene expressionGO:00106082130.024
positive regulation of programmed cell deathGO:00430682490.024
purine ribonucleoside catabolic processGO:00461303980.024
positive regulation of protein catabolic processGO:0045732750.024
neuron developmentGO:00486661130.024
cytokine productionGO:00018162470.023
regulation of cell substrate adhesionGO:0010810680.023
regulation of cellular response to stressGO:00801352440.023
protein lipid complex remodelingGO:0034368160.023
small molecule biosynthetic processGO:00442831570.023
response to cytokineGO:00340972320.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
Fly
vasodilationGO:004231140.023
regulation of lipid metabolic processGO:0019216960.023
positive regulation of cell deathGO:00109422630.023
small molecule catabolic processGO:0044282920.023
regulation of nucleotide metabolic processGO:00061402690.023
nuclear divisionGO:00002801280.023
neuron projection developmentGO:00311751060.023
ubiquitin dependent protein catabolic processGO:00065112060.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
meiosis iGO:000712740.023
regulation of immune responseGO:00507762010.023
neuron differentiationGO:00301821380.023
cardiovascular system developmentGO:00723582620.023
Zebrafish
nucleoside triphosphate catabolic processGO:00091433940.022
regulation of epithelial cell proliferationGO:00506781130.022
cellular protein complex assemblyGO:00436231880.022
cellular metal ion homeostasisGO:00068751460.022
organelle fissionGO:00482851490.022
phospholipid metabolic processGO:0006644990.022
regulation of protein catabolic processGO:00421761550.022
regulation of actin cytoskeleton organizationGO:00329561160.021
negative regulation of intracellular signal transductionGO:19025321830.021
generation of neuronsGO:00486991520.021
protein targetingGO:00066051870.021
cell activationGO:00017752130.021
glycerolipid biosynthetic processGO:0045017510.021
regulation of cytokine productionGO:00018172320.020
negative regulation of kinase activityGO:00336731060.020
positive regulation of nucleoside metabolic processGO:00459791860.020
oxidation reduction processGO:00551143960.020
positive regulation of rho protein signal transductionGO:003502540.020
segmentationGO:003528240.020
negative regulation of protein phosphorylationGO:00019331400.020
chemical homeostasisGO:00488783060.020
establishment of protein localization to organelleGO:00725941720.020
negative regulation of cellular amine metabolic processGO:003323930.020
regulation of cell morphogenesisGO:00226041530.020
epithelial cell migrationGO:00106311190.020
mrna processingGO:00063971330.020
macromolecular complex remodelingGO:0034367160.020
nucleoside triphosphate metabolic processGO:00091414220.020
immune effector processGO:00022521590.020
negative regulation of phosphorylationGO:00423261740.020
protein modification by small protein conjugationGO:00324463420.019
regulation of cellular amine metabolic processGO:0033238110.019
regulation of epithelial cell migrationGO:0010632930.019
purine nucleotide catabolic processGO:00061954050.019
reproductionGO:0000003630.019
Fly
actin filament organizationGO:00070151280.019
anion transportGO:00068201610.019
immune responseGO:00069553070.019
regulation of kinase activityGO:00435493140.019
mitotic spindle elongationGO:000002240.019
glycoprotein biosynthetic processGO:0009101910.019
cdc42 protein signal transductionGO:003248840.019
mitotic nuclear divisionGO:00070671190.019
regulation of mitotic cell cycle phase transitionGO:19019901180.018
neuromuscular junction developmentGO:000752830.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
purine containing compound biosynthetic processGO:0072522880.018
tissue migrationGO:00901301190.018
protein ubiquitinationGO:00165673140.018
single organism carbohydrate metabolic processGO:00447231930.018
defense responseGO:00069523150.018
regulation of blood vessel endothelial cell migrationGO:0043535300.018
ribonucleotide catabolic processGO:00092614050.018
positive regulation of protein kinase activityGO:00458601900.018
neurological system processGO:00508771630.018
regulation of receptor catabolic processGO:200064420.018
positive regulation of cell differentiationGO:00455972110.018
Fly
negative regulation of transportGO:00510511760.018
negative regulation of cell developmentGO:0010721480.018
ribonucleoside catabolic processGO:00424544060.018
response to biotic stimulusGO:00096072760.017
regulation of ion transportGO:00432691890.017
negative regulation of protein kinase activityGO:0006469980.017
negative regulation of cell cycle processGO:00109481210.017
metal ion transportGO:00300012720.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
ribose phosphate biosynthetic processGO:0046390820.017
organic hydroxy compound metabolic processGO:19016151470.017
chromatin modificationGO:00165682980.017
negative regulation of cellular component movementGO:00512711060.017
nucleoside phosphate catabolic processGO:19012924120.017
regulation of cellular protein catabolic processGO:1903362960.017
cell adhesionGO:00071553250.016
regulation of protein serine threonine kinase activityGO:00719001790.016
sterol transportGO:0015918390.016
lipid biosynthetic processGO:00086101770.016
embryo developmentGO:00097901230.016
purine containing compound catabolic processGO:00725234110.016
hemopoiesisGO:00300971800.016
plasma lipoprotein particle organizationGO:0071827220.016
long term memoryGO:000761620.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
immune system developmentGO:00025201950.016
negative regulation of cell cycleGO:00457861930.016
response to growth factorGO:00708482050.016
regulation of cell cycleGO:00517263930.016
response to organic cyclic compoundGO:00140702040.016
epithelium migrationGO:00901321190.016
chylomicron remnant clearanceGO:003438240.016
organonitrogen compound biosynthetic processGO:19015662000.016
negative regulation of catabolic processGO:00098951040.016
positive regulation of cell proliferationGO:00082843010.015
proteasomal protein catabolic processGO:00104981760.015
cytoplasmic transportGO:00164823790.015
regulation of cell adhesionGO:00301551660.015
regulation of mrna metabolic processGO:1903311530.015
regulation of endopeptidase activityGO:00525481700.015
gtp metabolic processGO:00460392390.015
negative regulation of neuron differentiationGO:0045665210.015
spermatid differentiationGO:004851540.015
endocytosisGO:00068971590.015
cation transportGO:00068123310.015
spermatid developmentGO:000728640.015
establishment of protein localization to membraneGO:00901501210.015
positive regulation of protein transportGO:00512221350.015
glycerolipid metabolic processGO:00464861070.015
regulation of protein complex assemblyGO:00432541470.015
regulation of rna splicingGO:0043484620.015
cellular ion homeostasisGO:00068731680.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
regulation of cell activationGO:00508651250.015
calcium ion homeostasisGO:00550741220.015
negative regulation of transferase activityGO:00513481240.015
regulation of peptidase activityGO:00525471800.015
response to oxidative stressGO:00069791210.015
methylationGO:00322591060.015
carbohydrate metabolic processGO:00059752070.015
dendritic spine maintenanceGO:009706210.015
metal ion homeostasisGO:00550651690.014
rhythmic behaviorGO:000762220.014
cellular response to cytokine stimulusGO:00713451810.014
covalent chromatin modificationGO:00165692540.014
dna conformation changeGO:00711031130.014
actin polymerization or depolymerizationGO:0008154560.014
negative regulation of immune system processGO:00026831360.014
negative regulation of nervous system developmentGO:0051961280.014
glycosyl compound catabolic processGO:19016584130.014
nucleotide biosynthetic processGO:00091651090.014
acylglycerol metabolic processGO:0006639270.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
head developmentGO:00603221080.014
protein dna complex subunit organizationGO:0071824800.014
positive regulation of transferase activityGO:00513472270.014
rna interferenceGO:001624640.014
purine ribonucleoside triphosphate catabolic processGO:00092073910.014
cellular response to oxygen containing compoundGO:19017012760.014
lipoprotein biosynthetic processGO:0042158330.014
negative regulation of locomotionGO:00400131180.014
endomembrane system organizationGO:00102561960.014
regulation of rho protein signal transductionGO:0035023790.014
cholesterol catabolic processGO:000670730.014
cation homeostasisGO:00550801890.014
negative regulation of protein serine threonine kinase activityGO:0071901570.014
purine nucleoside catabolic processGO:00061523980.014
plasma lipoprotein particle remodelingGO:0034369160.013
cellular calcium ion homeostasisGO:00068741170.013
regulation of cell projection organizationGO:00313441070.013
positive regulation of immune responseGO:00507781590.013
cell substrate adhesionGO:00315891320.013
negative regulation of endothelial cell migrationGO:0010596290.013
regulation of immune effector processGO:0002697910.013
organic anion transportGO:00157111030.013
circulatory system developmentGO:00723592620.013
Zebrafish
response to abiotic stimulusGO:00096283360.013
negative regulation of protein transportGO:0051224750.013
lymphocyte activationGO:00466491330.013
negative regulation of neurogenesisGO:0050768260.013
behaviorGO:00076101120.013
microtubule organizing center organizationGO:0031023620.013
regulation of intracellular transportGO:00323861950.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
nucleoside catabolic processGO:00091644080.013
cellular amide metabolic processGO:0043603690.013
circadian behaviorGO:004851220.013
mrna splicing via spliceosomeGO:0000398890.013
positive regulation of cellular protein catabolic processGO:1903364370.013
regulation of plasma lipoprotein particle levelsGO:0097006320.013
positive regulation of cholesterol esterificationGO:001087360.013
cholesterol homeostasisGO:0042632280.013
growthGO:00400072020.013
regulation of purine nucleotide catabolic processGO:00331212050.013
lipoprotein metabolic processGO:0042157420.013
regulation of intracellular protein transportGO:00331571230.013
cellular biogenic amine metabolic processGO:0006576340.013
reproductive system developmentGO:0061458560.013
response to radiationGO:00093141510.013
guanosine containing compound catabolic processGO:19010692390.013
regulation of endothelial cell migrationGO:0010594670.013
nucleoside phosphate biosynthetic processGO:19012931090.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
positive regulation of phospholipid transportGO:200114040.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
regulation of ras gtpase activityGO:00323181280.012
macromolecule methylationGO:0043414970.012
receptor metabolic processGO:0043112810.012
agingGO:0007568660.012
negative regulation of epithelial cell proliferationGO:0050680480.012
single organism cell adhesionGO:00986021790.012
regulation of nucleotide catabolic processGO:00308112050.012
developmental programmed cell deathGO:001062330.012
negative regulation of cell motilityGO:20001461040.012
leukocyte activationGO:00453211640.012
phospholipid effluxGO:0033700110.012
gtp catabolic processGO:00061842370.012
somitogenesisGO:000175620.012
immune response activating signal transductionGO:0002757900.012
regulation of neural precursor cell proliferationGO:200017740.012
dephosphorylationGO:00163112090.012
regulation of cyclic nucleotide metabolic processGO:0030799630.012
negative regulation of cell cycle phase transitionGO:1901988890.012
cholesterol effluxGO:0033344280.012
apoptotic signaling pathwayGO:00971902680.012
sterol homeostasisGO:0055092280.012
negative regulation of mitotic cell cycleGO:00459301020.012
oocyte developmentGO:004859910.012
divalent metal ion transportGO:00708381520.012
response to fungusGO:000962040.012
lipid transportGO:0006869900.011
gonad developmentGO:0008406340.011
regulation of cell developmentGO:00602841610.011
organophosphate ester transportGO:0015748320.011
protein dna complex assemblyGO:0065004640.011
positive regulation of cell adhesionGO:0045785840.011
cellular cation homeostasisGO:00300031630.011
negative regulation of cell migrationGO:00303361020.011
regulation of response to external stimulusGO:00321012220.011
phospholipid biosynthetic processGO:0008654440.011
lipid modificationGO:0030258840.011
sterol catabolic processGO:001612730.011
negative regulation of peptidase activityGO:0010466910.011
response to other organismGO:00517072610.011
histone modificationGO:00165702510.011
actin filament bundle organizationGO:0061572540.011
sex differentiationGO:0007548450.011
positive regulation of gtp catabolic processGO:00331261660.011
cellular component disassemblyGO:0022411920.011
alcohol metabolic processGO:00060661140.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
glycerophospholipid biosynthetic processGO:0046474400.011
motor neuron axon guidanceGO:000804520.011
regulation of protein maturationGO:19033171500.011
regulation of hemostasisGO:1900046420.011
protein secretionGO:0009306980.011
guanosine containing compound metabolic processGO:19010682440.011
cell divisionGO:00513011680.011
carboxylic acid biosynthetic processGO:0046394970.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
anterior posterior axis specificationGO:000994820.011
protein alkylationGO:0008213740.011
positive regulation of nucleotide catabolic processGO:00308131850.011
regulation of gtpase activityGO:00430871800.011
developmental process involved in reproductionGO:0003006660.011
Fly
response to external biotic stimulusGO:00432072610.011
protein localization to nucleusGO:00345041360.011
triglyceride metabolic processGO:0006641230.011
atp catabolic processGO:00062001570.011
ribonucleotide biosynthetic processGO:0009260810.010
negative regulation of secretion by cellGO:1903531520.010
very low density lipoprotein particle remodelingGO:0034372100.010
steroid metabolic processGO:0008202940.010
negative regulation of cell cycle g1 s phase transitionGO:1902807290.010
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.010
regulation of chromosome organizationGO:00330441030.010
negative regulation of cell adhesionGO:0007162640.010
positive regulation of kinase activityGO:00336742040.010
regulation of secretionGO:00510461940.010
alcohol biosynthetic processGO:0046165520.010
purine ribonucleotide catabolic processGO:00091544040.010
cell growthGO:00160491600.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
divalent inorganic cation transportGO:00725111580.010
rab protein signal transductionGO:003248240.010
positive regulation of cytoskeleton organizationGO:0051495830.010
cellular response to tumor necrosis factorGO:0071356630.010
innate immune responseGO:00450871780.010
reactive oxygen species biosynthetic processGO:190340940.010
protein maturationGO:00516042330.010
regulation of protein targetingGO:1903533910.010
organ morphogenesisGO:00098871470.010
transmembrane transportGO:00550853990.010
regulation of cell divisionGO:00513021160.010
regulation of bindingGO:00510981110.010

PDCD4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.118
hematopoietic system diseaseDOID:741000.047
disease of metabolismDOID:00146672950.046
inherited metabolic disorderDOID:6552420.035
disease of mental healthDOID:150700.027
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.021
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
cognitive disorderDOID:1561290.018
alzheimer s diseaseDOID:10652160.014
tauopathyDOID:680160.014
neurodegenerative diseaseDOID:12891020.014
dementiaDOID:1307190.014
lysosomal storage diseaseDOID:3211470.013
sensory system diseaseDOID:00501552030.013
bone marrow diseaseDOID:4961310.013
organ system cancerDOID:00506861640.012