Homo sapiens

60 known processes

SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

(Aliases: EPC-1,PEDF)

SERPINF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066293810.087
cellular ketone metabolic processGO:0042180800.077
regulation of cellular component movementGO:00512703340.075
Rat
cellular amino acid metabolic processGO:00065201160.075
regulation of cell differentiationGO:00455953930.067
cellular response to oxygen containing compoundGO:19017012760.063
Rat
cellular lipid metabolic processGO:00442553030.063
positive regulation of cellular amino acid metabolic processGO:004576430.059
negative regulation of protein metabolic processGO:00512483910.059
Human
negative regulation of cellular protein metabolic processGO:00322693530.056
Human
positive regulation of cellular amine metabolic processGO:003324070.055
cytokine productionGO:00018162470.054
Human
negative regulation of multicellular organismal processGO:00512413170.053
amine metabolic processGO:0009308440.053
immune responseGO:00069553070.052
Human
regulation of cytokine productionGO:00018172320.052
Human
defense responseGO:00069523150.052
Human Rat
regulation of cellular ketone metabolic processGO:0010565500.052
regulation of cell migrationGO:00303342890.052
Rat
response to oxygen containing compoundGO:19017003690.051
Rat
regulation of cellular amine metabolic processGO:0033238110.051
response to abiotic stimulusGO:00096283360.050
Rat
regulation of cellular amino acid metabolic processGO:000652160.050
regulation of locomotionGO:00400123290.049
Rat
cellular amine metabolic processGO:0044106410.044
regulation of cell motilityGO:20001452990.044
Rat
negative regulation of catalytic activityGO:00430863350.043
Human
regulation of proteolysisGO:00301622930.042
Human
regenerationGO:003109940.042
response to woundingGO:00096111680.042
Human Rat
cell chemotaxisGO:00603261120.041
cellular macromolecule catabolic processGO:00442653800.041
regulation of transferase activityGO:00513383550.039
regulation of peptidase activityGO:00525471800.038
Human
response to cytokineGO:00340972320.037
vesicle mediated transportGO:00161923710.037
post embryonic developmentGO:000979120.037
small molecule biosynthetic processGO:00442831570.037
protein processingGO:00164852260.035
Human
positive regulation of transportGO:00510503360.035
innate immune responseGO:00450871780.034
Human
monocarboxylic acid metabolic processGO:00327871850.033
protein maturationGO:00516042330.033
Human
negative regulation of cell deathGO:00605483450.033
Rat
positive regulation of phosphorylationGO:00423273940.032
Human
negative regulation of complement activation lectin pathwayGO:000186920.032
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.032
lipid biosynthetic processGO:00086101770.031
response to external biotic stimulusGO:00432072610.031
response to other organismGO:00517072610.031
negative regulation of immune system processGO:00026831360.031
Human
regulation of protein maturationGO:19033171500.030
Human
multicellular organismal agingGO:001025930.030
determination of adult lifespanGO:000834020.029
negative regulation of phosphate metabolic processGO:00459362670.029
enzyme linked receptor protein signaling pathwayGO:00071673030.029
negative regulation of hydrolase activityGO:00513461820.029
Human
mapk cascadeGO:00001652880.029
Human
regulation of response to external stimulusGO:00321012220.028
Human Rat
regulation of protein kinase activityGO:00458592890.028
organic acid biosynthetic processGO:0016053970.028
carboxylic acid biosynthetic processGO:0046394970.027
signal transduction by phosphorylationGO:00230142970.027
Human
positive regulation of cellular component organizationGO:00511303760.027
Human Rat
rhythmic behaviorGO:000762220.026
positive regulation of immune system processGO:00026842830.026
Human
negative regulation of proteolysisGO:00458611320.026
Human
fatty acid metabolic processGO:00066311150.026
positive regulation of protein phosphorylationGO:00019343130.026
response to biotic stimulusGO:00096072760.025
cardiovascular system developmentGO:00723582620.025
protein catabolic processGO:00301633250.025
negative regulation of programmed cell deathGO:00430693210.025
transmembrane transportGO:00550853990.025
vasculature developmentGO:00019441810.025
carbohydrate metabolic processGO:00059752070.025
cell substrate adhesionGO:00315891320.025
negative regulation of developmental processGO:00510932470.024
regulation of protein transportGO:00512232130.024
regulation of renal albumin absorptionGO:200053210.024
circulatory system developmentGO:00723592620.024
cellular response to endogenous stimulusGO:00714953360.024
Rat
apoptotic signaling pathwayGO:00971902680.024
cellular protein catabolic processGO:00442572610.024
regulation of kinase activityGO:00435493140.024
organonitrogen compound biosynthetic processGO:19015662000.024
positive regulation of mapk cascadeGO:00434101900.024
Human
regulation of protein processingGO:00706131500.024
Human
regulation of immune responseGO:00507762010.024
Human
single organism cellular localizationGO:19025803320.024
oxidation reduction processGO:00551143960.024
glycerolipid metabolic processGO:00464861070.024
cellular response to cytokine stimulusGO:00713451810.024
wound healingGO:00420601150.024
Human
cytoplasmic transportGO:00164823790.023
regulation of protein localizationGO:00328802960.023
immune effector processGO:00022521590.023
Human
organophosphate catabolic processGO:00464344300.023
cell activationGO:00017752130.023
positive regulation of cytokine productionGO:00018191670.023
Human
anatomical structure formation involved in morphogenesisGO:00486462840.023
secretionGO:00469032540.023
female gamete generationGO:000729220.023
positive regulation of transferase activityGO:00513472270.023
tissue regenerationGO:004224630.023
ras protein signal transductionGO:0007265730.023
positive regulation of kinase activityGO:00336742040.022
negative regulation of phosphorus metabolic processGO:00105632670.022
positive regulation of cell proliferationGO:00082843010.022
intracellular protein transportGO:00068862700.022
positive regulation of cell deathGO:00109422630.022
regulation of defense responseGO:00313471540.022
Human Rat
chemical homeostasisGO:00488783060.021
Rat
blood vessel morphogenesisGO:00485141620.021
negative regulation of cell proliferationGO:00082852280.021
Mouse
nervous system developmentGO:00073992930.021
regulation of cellular response to stressGO:00801352440.021
Human
nucleoside triphosphate metabolic processGO:00091414220.021
organic hydroxy compound metabolic processGO:19016151470.021
regulation of secretion by cellGO:19035301770.021
secretion by cellGO:00329402260.021
single organism carbohydrate metabolic processGO:00447231930.021
regulation of anatomical structure morphogenesisGO:00226032860.021
epithelium developmentGO:00604292270.021
regulation of establishment of protein localizationGO:00702012420.021
positive regulation of cellular component movementGO:00512721810.021
regulation of cell adhesionGO:00301551660.021
regulation of mapk cascadeGO:00434082620.020
Human
carbohydrate derivative biosynthetic processGO:19011372070.020
cell morphogenesisGO:00009022960.020
regulation of endopeptidase activityGO:00525481700.020
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.020
purine ribonucleoside metabolic processGO:00461284370.020
negative regulation of protein processingGO:00109551420.020
Human
cellular response to dna damage stimulusGO:00069743790.020
positive regulation of catabolic processGO:00098963100.020
negative regulation of response to woundingGO:1903035470.020
Human Rat
sulfur compound metabolic processGO:00067901010.019
cellular chemical homeostasisGO:00550821800.019
Rat
oogenesisGO:004847720.019
monocarboxylic acid biosynthetic processGO:0072330670.019
lipopolysaccharide transportGO:001592020.019
positive regulation of cell migrationGO:00303351720.019
segmentationGO:003528240.019
positive regulation of hydrolase activityGO:00513453310.019
negative regulation of phosphorylationGO:00423261740.019
purine nucleotide catabolic processGO:00061954050.019
ion transmembrane transportGO:00342203380.019
cell developmentGO:00484683280.019
positive regulation of protein kinase activityGO:00458601900.019
regulation of secretionGO:00510461940.019
epithelial cell proliferationGO:00506731280.019
Mouse
positive regulation of cellular catabolic processGO:00313312840.019
biological adhesionGO:00226103310.018
neurogenesisGO:00220081690.018
response to lipidGO:00339932060.018
Rat
reactive oxygen species metabolic processGO:0072593750.018
negative regulation of apoptotic processGO:00430663160.018
negative regulation of intracellular signal transductionGO:19025321830.018
negative regulation of transportGO:00510511760.018
protein oligomerizationGO:00512591730.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
purine nucleoside catabolic processGO:00061523980.018
purine containing compound catabolic processGO:00725234110.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
lipid localizationGO:00108761060.018
chemotaxisGO:00069351570.018
positive regulation of developmental processGO:00510943140.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
negative regulation of peptidase activityGO:0010466910.018
Human
cation transportGO:00068123310.018
cell adhesionGO:00071553250.018
blood vessel developmentGO:00015681720.018
epithelial cell migrationGO:00106311190.018
Rat
purine ribonucleoside catabolic processGO:00461303980.018
peptidyl tyrosine modificationGO:00182121700.017
mitochondrion organizationGO:00070051560.017
small gtpase mediated signal transductionGO:0007264780.017
rho protein signal transductionGO:0007266260.017
response to nitrogen compoundGO:19016981840.017
cellular component morphogenesisGO:00329893140.017
circadian behaviorGO:004851220.017
dephosphorylationGO:00163112090.017
negative regulation of cellular component organizationGO:00511292350.017
ion homeostasisGO:00508012300.017
regulation of vesicle mediated transportGO:00606271300.017
membrane organizationGO:00610242920.017
regulation of response to woundingGO:19030341010.017
Human Rat
negative regulation of protein maturationGO:19033181420.017
Human
regulation of apoptotic signaling pathwayGO:20012331750.017
nucleoside phosphate catabolic processGO:19012924120.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
epithelial cell differentiationGO:00308551410.017
positive regulation of secretionGO:00510471160.017
endomembrane system organizationGO:00102561960.017
nucleoside catabolic processGO:00091644080.016
lipid transportGO:0006869900.016
positive regulation of protein transportGO:00512221350.016
positive regulation of programmed cell deathGO:00430682490.016
negative regulation of protein modification processGO:00314002000.016
cellular amide metabolic processGO:0043603690.016
single organism membrane organizationGO:00448022680.016
oxidative stress induced premature senescenceGO:009040330.016
ribonucleoside catabolic processGO:00424544060.016
locomotory behaviorGO:000762610.016
regulation of leukocyte migrationGO:0002685630.016
negative regulation of blood coagulationGO:0030195220.016
Human
positive regulation of apoptotic processGO:00430652460.016
regulation of protein serine threonine kinase activityGO:00719001790.016
hindbrain developmentGO:003090230.016
negative regulation of response to external stimulusGO:0032102830.016
Human Rat
ossificationGO:00015031210.016
blastoderm segmentationGO:000735020.016
maintenance of locationGO:00512351120.016
angiogenesisGO:00015251470.016
memoryGO:000761330.016
Rat
protein localization to membraneGO:00726571600.016
cellular homeostasisGO:00197251960.016
Rat
ribonucleotide catabolic processGO:00092614050.016
regulation of nucleotide metabolic processGO:00061402690.016
cellular response to lipidGO:00713961270.016
Rat
vitamin e metabolic processGO:004236010.016
ameboidal type cell migrationGO:00016671350.016
Rat
positive regulation of organelle organizationGO:00106381950.016
Human
regulation of purine nucleotide metabolic processGO:19005422640.016
negative regulation of cell migrationGO:00303361020.016
Rat
organ morphogenesisGO:00098871470.016
response to hormoneGO:00097251750.016
Rat
hematopoietic or lymphoid organ developmentGO:00485341860.016
cytokine secretionGO:0050663640.015
multicellular organismal macromolecule metabolic processGO:0044259290.015
Human
ribonucleoside triphosphate metabolic processGO:00091994120.015
system processGO:00030083490.015
Rat
protein localization to organelleGO:00333652800.015
nucleoside triphosphate catabolic processGO:00091433940.015
positive regulation of cell motilityGO:20001471770.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
small molecule catabolic processGO:0044282920.015
nucleotide catabolic processGO:00091664080.015
positive regulation of cell differentiationGO:00455972110.015
negative regulation of locomotionGO:00400131180.015
Rat
negative regulation of protein phosphorylationGO:00019331400.015
wnt signaling pathwayGO:00160551560.015
posttranscriptional regulation of gene expressionGO:00106082130.015
purine ribonucleotide catabolic processGO:00091544040.015
spermatid differentiationGO:004851540.015
activation of immune responseGO:00022531140.015
Human
actin cytoskeleton organizationGO:00300362070.015
Human
epithelium migrationGO:00901321190.015
Rat
positive regulation of secretion by cellGO:19035321080.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of protein secretionGO:0050708860.015
guanosine containing compound metabolic processGO:19010682440.015
actin filament based processGO:00300292240.015
Human
regulation of dna metabolic processGO:00510521530.015
regulation of cytokine secretionGO:0050707570.014
regulation of vasculature developmentGO:1901342970.014
prostate gland developmentGO:003085030.014
Mouse
regulation of cell activationGO:00508651250.014
positive regulation of immune responseGO:00507781590.014
Human
regulation of protein catabolic processGO:00421761550.014
regulation of complement activation lectin pathwayGO:000186820.014
Human
tissue migrationGO:00901301190.014
Rat
positive regulation of locomotionGO:00400171860.014
negative regulation of cellular amine metabolic processGO:003323930.014
positive regulation of leukocyte activationGO:0002696800.014
response to organonitrogen compoundGO:00102431560.014
renal system process involved in regulation of blood volumeGO:000197740.014
regulation of macrophage chemotaxisGO:001075840.014
inflammatory responseGO:0006954790.014
Human Rat
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
regulation of intracellular transportGO:00323861950.014
negative regulation of endopeptidase activityGO:0010951840.014
Human
mitotic cell cycleGO:00002783260.014
mitotic cell cycle processGO:19030472860.014
neuromuscular junction developmentGO:000752830.014
regulation of cell cycleGO:00517263930.014
circadian sleep wake cycle sleepGO:005080220.014
negative regulation of platelet derived growth factor receptor signaling pathwayGO:001064240.014
cellular macromolecular complex assemblyGO:00346223240.014
response to molecule of bacterial originGO:0002237820.014
peptidyl tyrosine phosphorylationGO:00181081700.014
regulation of chemokine productionGO:0032642310.014
leukocyte chemotaxisGO:0030595760.014
nitrogen compound transportGO:00717051910.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
peripheral nervous system developmentGO:000742220.013
inorganic cation transmembrane transportGO:00986621940.013
response to radiationGO:00093141510.013
gtp metabolic processGO:00460392390.013
cellular response to growth factor stimulusGO:00713631970.013
metal ion transportGO:00300012720.013
reactive nitrogen species metabolic processGO:200105730.013
metencephalon developmentGO:002203720.013
canonical wnt signaling pathwayGO:00600701160.013
cofactor metabolic processGO:0051186870.013
cation homeostasisGO:00550801890.013
regulation of cell developmentGO:00602841610.013
regulation of circadian sleep wake cycleGO:004274920.013
regulation of blood coagulationGO:0030193420.013
Human
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.013
cerebellum developmentGO:002154920.013
regulation of erk1 and erk2 cascadeGO:0070372990.013
Human
protein secretionGO:0009306980.013
glycosyl compound catabolic processGO:19016584130.013
embryonic epithelial tube formationGO:000183840.013
negative regulation of synaptic transmissionGO:005080520.013
regulation of cell cycle processGO:00105642660.013
endocytosisGO:00068971590.013
negative regulation of cellular component movementGO:00512711060.013
Rat
salivary gland morphogenesisGO:000743540.012
fatty acid biosynthetic processGO:0006633460.012
regulation of ras protein signal transductionGO:00465781550.012
coagulationGO:0050817780.012
Human
guanosine containing compound catabolic processGO:19010692390.012
protein modification by small protein conjugationGO:00324463420.012
negative regulation of catabolic processGO:00098951040.012
regulation of epithelial cell proliferationGO:00506781130.012
Mouse
motor neuron axon guidanceGO:000804520.012
response to bacteriumGO:00096171440.012
anatomical structure homeostasisGO:00602491000.012
developmental programmed cell deathGO:001062330.012
blood coagulationGO:0007596760.012
Human
cell junction maintenanceGO:003433140.012
rna interferenceGO:001624640.012
immune response regulating signaling pathwayGO:0002764970.012
compound eye developmentGO:004874910.012
negative regulation of cytokine productionGO:0001818820.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
adult locomotory behaviorGO:000834410.012
response to inorganic substanceGO:00100351270.012
Rat
positive regulation of synaptic transmissionGO:005080640.012
response to oxidative stressGO:00069791210.012
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.012
cellular protein complex assemblyGO:00436231880.012
microtubule based processGO:00070172100.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
limbic system developmentGO:002176130.012
nuclear transportGO:00511691790.012
negative regulation of cell motilityGO:20001461040.012
Rat
regulation of cellular component biogenesisGO:00440872810.012
Human
tripartite regional subdivisionGO:000735120.012
glycoprotein metabolic processGO:00091001100.012
taxisGO:00423301570.012
regulation of cytoplasmic transportGO:19036491490.012
monosaccharide metabolic processGO:0005996740.011
morphogenesis of embryonic epitheliumGO:001633140.011
sleepGO:003043120.011
anion transportGO:00068201610.011
detection of chemical stimulusGO:0009593550.011
inorganic ion transmembrane transportGO:00986602310.011
negative regulation of blood pressureGO:004577630.011
proteasomal protein catabolic processGO:00104981760.011
plasma membrane organizationGO:00070091150.011
activation of protein kinase activityGO:0032147900.011
negative regulation of cell cycleGO:00457861930.011
cellular lipid catabolic processGO:0044242650.011
negative regulation of plasminogen activationGO:001075740.011
Human
regulation of reactive oxygen species biosynthetic processGO:190342630.011
ubiquitin dependent protein catabolic processGO:00065112060.011
regulation of cytoskeleton organizationGO:00514931770.011
Human
leukocyte activationGO:00453211640.011
regulation of purine nucleotide catabolic processGO:00331212050.011
spermatid developmentGO:000728640.011
establishment of tissue polarityGO:000716430.011
positive regulation of cellular component biogenesisGO:00440891580.011
Human
myoblast fusionGO:000752010.011
gtp catabolic processGO:00061842370.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
positive regulation of acute inflammatory responseGO:000267520.011
cell fate determinationGO:000170930.011
anterior posterior axis specification embryoGO:000859520.011
negative regulation of interleukin 1 secretionGO:005071140.011
inner ear morphogenesisGO:004247240.011
organ formationGO:004864530.011
cellular ion homeostasisGO:00068731680.011
multi organism cellular processGO:00447641560.011
cellular response to abiotic stimulusGO:00712141170.011
positive regulation of proteolysisGO:00458621420.011
actin mediated cell contractionGO:0070252120.011
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.011
negative regulation of transferase activityGO:00513481240.011
protein targetingGO:00066051870.011
organic hydroxy compound transportGO:0015850630.011
immune system developmentGO:00025201950.011
hemopoiesisGO:00300971800.011
syncytium formation by plasma membrane fusionGO:000076820.011
regulation of meiotic cell cycleGO:005144540.011
regulation of hormone levelsGO:00108171250.011
divalent inorganic cation homeostasisGO:00725071360.011
positive regulation of epithelial cell migrationGO:0010634550.011
negative regulation of cellular catabolic processGO:0031330830.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
organelle assemblyGO:00709251760.011
cdc42 protein signal transductionGO:003248840.011
cytokine mediated signaling pathwayGO:00192211090.011
chromatin organizationGO:00063253510.011
steroid metabolic processGO:0008202940.011
negative regulation of organelle organizationGO:00106391260.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
phospholipid metabolic processGO:0006644990.011
endothelial cell migrationGO:0043542860.011
Rat
establishment of protein localization to organelleGO:00725941720.011
negative regulation of cell adhesionGO:0007162640.011
regulation of blood pressureGO:0008217300.011
regulation of transmembrane transportGO:00347621390.011
oocyte developmentGO:004859910.011
protein ubiquitinationGO:00165673140.011
renal albumin absorptionGO:009701810.011
coenzyme metabolic processGO:0006732650.011
cell projection organizationGO:00300302520.011
Rat
regulation of lipid metabolic processGO:0019216960.010
nucleocytoplasmic transportGO:00069131760.010
cellular response to organonitrogen compoundGO:00714171240.010
oocyte differentiationGO:000999420.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
modification dependent protein catabolic processGO:00199412090.010
cation transmembrane transportGO:00986552380.010
cellular response to external stimulusGO:00714961110.010
i kappab kinase nf kappab signalingGO:00072491660.010
protein localization to nucleusGO:00345041360.010
behaviorGO:00076101120.010
Rat
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
spindle elongationGO:005123140.010
regulation of leukocyte activationGO:00026941150.010
regulation of intracellular protein transportGO:00331571230.010
neural tube closureGO:000184330.010
renal protein absorptionGO:009701710.010
negative regulation of apoptotic signaling pathwayGO:2001234970.010
osteoblast differentiationGO:0001649920.010
cellular metal ion homeostasisGO:00068751460.010
organic anion transportGO:00157111030.010
response to growth factorGO:00708482050.010
positive regulation of nucleoside metabolic processGO:00459791860.010
response to tumor necrosis factorGO:0034612760.010
regulation of tumor necrosis factor productionGO:0032680430.010
detection of mechanical stimulusGO:005098240.010
microtubule cytoskeleton organizationGO:00002261760.010

SERPINF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.066
sensory system diseaseDOID:00501552030.066
disease of metabolismDOID:00146672950.057
eye and adnexa diseaseDOID:14921500.053
musculoskeletal system diseaseDOID:172230.048
eye diseaseDOID:56141490.046
retinal diseaseDOID:56791180.032
central nervous system diseaseDOID:3311860.026
retinal degenerationDOID:8466890.026
myopathyDOID:4231040.024
muscular diseaseDOID:00800001140.024
muscle tissue diseaseDOID:661130.024
inherited metabolic disorderDOID:6552420.021
immune system diseaseDOID:29141550.021
hematopoietic system diseaseDOID:741000.018
macular degenerationDOID:4448200.017
degeneration of macula and posterior poleDOID:2007170.017
age related macular degenerationDOID:10871170.017
connective tissue diseaseDOID:651090.016
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
muscular dystrophyDOID:9884510.014
congenital muscular dystrophyDOID:0050557220.014
neurodegenerative diseaseDOID:12891020.014
disease of mental healthDOID:150700.014
lysosomal storage diseaseDOID:3211470.012
anemiaDOID:2355550.010
bone diseaseDOID:0080001880.008
bone development diseaseDOID:0080006550.008
osteochondrodysplasiaDOID:2256350.008
osteogenesis imperfectaDOID:12347130.006