Homo sapiens

159 known processes

ARFGEF2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

(Aliases: BIG2,dJ1164I10.1,PVNH2,FLJ23723)

ARFGEF2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of rho gtpase activityGO:003425940.998
Human
regulation of establishment of cell polarityGO:200011450.969
Human
regulation of actin filament polymerizationGO:0030833500.935
Human
protein glycosylation in golgiGO:003357830.883
Human
positive regulation of glycoprotein biosynthetic processGO:001056060.859
Human
actin filament polymerizationGO:0030041450.790
Human
negative regulation of nucleotide catabolic processGO:0030812160.702
Human
gtp metabolic processGO:00460392390.690
positive regulation of glycoprotein metabolic processGO:190302080.686
Human
regulation of actin filament lengthGO:0030832560.635
Human
regulation of glycoprotein metabolic processGO:1903018190.614
Human
regulation of wound healingGO:0061041560.603
Human
gtp catabolic processGO:00061842370.602
small gtpase mediated signal transductionGO:0007264780.599
regulation of actin filament based processGO:00329701410.592
Human
negative regulation of ras gtpase activityGO:003426160.591
Human
regulation of establishment or maintenance of cell polarityGO:003287870.579
Human
golgi vesicle transportGO:0048193800.578
glycoprotein biosynthetic processGO:0009101910.574
Human
regulation of protein polymerizationGO:0032271630.569
Human
rho protein signal transductionGO:0007266260.567
actin filament based processGO:00300292240.554
Human
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.554
regulation of response to woundingGO:19030341010.551
Human
carbohydrate derivative biosynthetic processGO:19011372070.528
Human
macromolecule glycosylationGO:0043413630.524
Human
vesicle mediated transportGO:00161923710.516
ras protein signal transductionGO:0007265730.497
regulation of gtp catabolic processGO:00331241800.495
guanosine containing compound metabolic processGO:19010682440.480
negative regulation of actin filament polymerizationGO:0030837100.470
Human
regulation of cellular carbohydrate metabolic processGO:0010675470.440
Human
cellular protein complex assemblyGO:00436231880.431
Human
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.429
glycosyl compound catabolic processGO:19016584130.428
post golgi vesicle mediated transportGO:0006892360.417
purine nucleoside triphosphate metabolic processGO:00091444120.402
purine ribonucleotide catabolic processGO:00091544040.400
positive regulation of gtpase activityGO:00435471660.398
glycosylationGO:0070085710.391
Human
nucleoside phosphate catabolic processGO:19012924120.390
guanosine containing compound catabolic processGO:19010692390.385
regulation of carbohydrate metabolic processGO:0006109540.382
Human
actin filament organizationGO:00070151280.381
Human
regulation of nucleotide catabolic processGO:00308112050.374
tumor necrosis factor superfamily cytokine productionGO:0071706450.364
purine nucleoside triphosphate catabolic processGO:00091463920.347
negative regulation of protein polymerizationGO:0032272160.334
Human
tumor necrosis factor productionGO:0032640430.334
regulation of small gtpase mediated signal transductionGO:00510561560.334
Human
regulation of protein glycosylationGO:006004960.328
Human
response to woundingGO:00096111680.327
Human
positive regulation of nucleotide metabolic processGO:00459812300.326
positive regulation of carbohydrate metabolic processGO:0045913210.321
Human
regulation of tumor necrosis factor productionGO:0032680430.321
regulation of cytokine productionGO:00018172320.315
regulation of purine nucleotide metabolic processGO:19005422640.314
regulation of cytoskeleton organizationGO:00514931770.310
Human
positive regulation of catabolic processGO:00098963100.303
post embryonic developmentGO:000979120.301
cellular carbohydrate metabolic processGO:0044262840.300
Human
endomembrane system organizationGO:00102561960.300
receptor metabolic processGO:0043112810.297
membrane organizationGO:00610242920.297
ribonucleoside catabolic processGO:00424544060.296
purine ribonucleoside catabolic processGO:00461303980.293
ribonucleoside triphosphate catabolic processGO:00092033910.287
positive regulation of response to woundingGO:1903036280.286
Human
purine ribonucleoside triphosphate catabolic processGO:00092073910.285
nucleotide catabolic processGO:00091664080.283
positive regulation of tumor necrosis factor productionGO:0032760210.280
single organism carbohydrate metabolic processGO:00447231930.279
Human
regulation of cellular component sizeGO:0032535820.278
Human
regulation of gtpase activityGO:00430871800.277
endosome organizationGO:0007032200.271
positive regulation of nucleotide catabolic processGO:00308131850.271
ribonucleotide catabolic processGO:00092614050.270
cellular macromolecular complex assemblyGO:00346223240.267
Human
ribonucleoside triphosphate metabolic processGO:00091994120.256
nucleoside triphosphate catabolic processGO:00091433940.246
regulation of nucleoside metabolic processGO:00091182090.245
nucleoside catabolic processGO:00091644080.245
negative regulation of cytoskeleton organizationGO:0051494450.241
Human
purine containing compound catabolic processGO:00725234110.239
negative regulation of phosphorus metabolic processGO:00105632670.238
Human
negative regulation of cellular component organizationGO:00511292350.227
Human
organophosphate catabolic processGO:00464344300.222
negative regulation of catabolic processGO:00098951040.221
Human
regulation of rho gtpase activityGO:0032319660.219
Human
negative regulation of catalytic activityGO:00430863350.219
Human
positive regulation of cytokine productionGO:00018191670.219
negative regulation of hydrolase activityGO:00513461820.219
Human
negative regulation of cellular catabolic processGO:0031330830.215
Human
carbohydrate metabolic processGO:00059752070.213
Human
cytokine productionGO:00018162470.206
positive regulation of cellular catabolic processGO:00313312840.202
actin cytoskeleton organizationGO:00300362070.199
Human
regulation of anatomical structure sizeGO:00900661010.196
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.192
positive regulation of hydrolase activityGO:00513453310.188
negative regulation of nucleotide metabolic processGO:0045980290.186
Human
regulation of ras protein signal transductionGO:00465781550.176
Human
negative regulation of phosphate metabolic processGO:00459362670.174
Human
negative regulation of organelle organizationGO:00106391260.166
Human
regulation of cellular component biogenesisGO:00440872810.165
Human
regulation of nucleotide metabolic processGO:00061402690.157
regulation of ras gtpase activityGO:00323181280.142
Human
regulation of rho protein signal transductionGO:0035023790.137
Human
purine nucleoside catabolic processGO:00061523980.135
regulation of protein complex assemblyGO:00432541470.132
Human
negative regulation of purine nucleotide metabolic processGO:1900543280.115
Human
regulation of glycoprotein biosynthetic processGO:0010559140.115
Human
cytoplasmic transportGO:00164823790.112
regulation of cell differentiationGO:00455953930.110
golgi to plasma membrane transportGO:0006893210.104
negative regulation of gtpase activityGO:0034260110.100
Human
endocytosisGO:00068971590.094
phagocytosis engulfmentGO:000691170.089
positive regulation of cellular component organizationGO:00511303760.084
apoptotic cell clearanceGO:0043277120.083
negative regulation of protein complex assemblyGO:0031333430.081
Human
anterior posterior axis specificationGO:000994820.079
metal ion transportGO:00300012720.076
establishment of cell polarityGO:0030010220.074
Human
protein modification by small protein conjugationGO:00324463420.074
locomotory behaviorGO:000762610.073
positive regulation of phosphorylationGO:00423273940.065
proteasomal protein catabolic processGO:00104981760.064
ion transmembrane transportGO:00342203380.063
receptor mediated endocytosisGO:0006898840.063
cation transportGO:00068123310.060
determination of adult lifespanGO:000834020.057
regulation of kinase activityGO:00435493140.057
regulation of ion transportGO:00432691890.057
phagocytosisGO:0006909420.056
inorganic ion transmembrane transportGO:00986602310.054
protein autophosphorylationGO:00467771230.053
system processGO:00030083490.053
female gamete generationGO:000729220.053
spermatid differentiationGO:004851540.052
mitochondrion organizationGO:00070051560.052
calcium ion homeostasisGO:00550741220.051
regulation of transferase activityGO:00513383550.051
spermatid developmentGO:000728640.051
metal ion homeostasisGO:00550651690.050
protein catabolic processGO:00301633250.049
establishment or maintenance of cell polarityGO:0007163310.048
Human
oocyte developmentGO:004859910.048
cellular protein catabolic processGO:00442572610.047
oxidation reduction processGO:00551143960.044
positive regulation of mapk cascadeGO:00434101900.044
transmembrane transportGO:00550853990.044
single organism membrane organizationGO:00448022680.044
cation homeostasisGO:00550801890.042
regulation of anatomical structure morphogenesisGO:00226032860.042
cellular divalent inorganic cation homeostasisGO:00725031280.041
cellular macromolecule catabolic processGO:00442653800.040
positive regulation of purine nucleotide metabolic processGO:19005442270.040
anterior posterior axis specification embryoGO:000859520.039
phosphorylation of rna polymerase ii c terminal domainGO:007081630.039
regulation of axon guidanceGO:190266730.039
oogenesisGO:004847720.038
endosomal transportGO:00161971290.038
positive regulation of transportGO:00510503360.038
embryo developmentGO:00097901230.037
neural tube formationGO:000184130.037
protein localization to organelleGO:00333652800.037
apoptotic signaling pathwayGO:00971902680.036
compound eye developmentGO:004874910.036
cellular cation homeostasisGO:00300031630.036
engulfment of apoptotic cellGO:004365220.036
positive regulation of cellular amine metabolic processGO:003324070.035
regulation of protein localizationGO:00328802960.034
oocyte differentiationGO:000999420.034
cell growthGO:00160491600.034
embryonic forelimb morphogenesisGO:003511540.033
ion homeostasisGO:00508012300.033
proteolysis involved in cellular protein catabolic processGO:00516032440.033
anatomical structure formation involved in morphogenesisGO:00486462840.033
protein ubiquitinationGO:00165673140.031
regulation of response to external stimulusGO:00321012220.031
tube morphogenesisGO:0035239950.031
immune responseGO:00069553070.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
divalent inorganic cation homeostasisGO:00725071360.030
memoryGO:000761330.030
hindbrain developmentGO:003090230.030
regulation of proteolysisGO:00301622930.029
protein processingGO:00164852260.029
tripartite regional subdivisionGO:000735120.029
cellular lipid metabolic processGO:00442553030.029
regulation of map kinase activityGO:00434051080.028
axon cargo transportGO:000808820.028
glycerolipid metabolic processGO:00464861070.028
organonitrogen compound biosynthetic processGO:19015662000.027
regulation of protein kinase activityGO:00458592890.027
neuromuscular junction developmentGO:000752830.027
mapk cascadeGO:00001652880.026
meiosis iGO:000712740.026
hematopoietic or lymphoid organ developmentGO:00485341860.026
organ morphogenesisGO:00098871470.025
segmentationGO:003528240.025
modification dependent protein catabolic processGO:00199412090.025
immune system developmentGO:00025201950.025
protein oligomerizationGO:00512591730.024
positive regulation of organelle organizationGO:00106381950.024
photoreceptor cell differentiationGO:004653020.024
covalent chromatin modificationGO:00165692540.024
cellular calcium ion homeostasisGO:00068741170.024
cellular metal ion homeostasisGO:00068751460.024
regulation of cell cycle processGO:00105642660.024
neurological system processGO:00508771630.024
regulation of axon extension involved in axon guidanceGO:004884120.023
canonical wnt signaling pathwayGO:00600701160.023
regulation of cellular component movementGO:00512703340.022
glycoprotein metabolic processGO:00091001100.022
Human
negative regulation of protein modification processGO:00314002000.022
maintenance of locationGO:00512351120.022
nucleotide biosynthetic processGO:00091651090.022
regulation of locomotionGO:00400123290.022
negative regulation of cellular protein metabolic processGO:00322693530.022
cellular ion homeostasisGO:00068731680.022
organophosphate biosynthetic processGO:00904071630.022
nucleoside phosphate biosynthetic processGO:19012931090.022
blastoderm segmentationGO:000735020.022
cellular ketone metabolic processGO:0042180800.021
nucleus localizationGO:005164710.021
regulation of metal ion transportGO:00109591200.021
response to disaccharideGO:003428510.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
regulation of mapk cascadeGO:00434082620.021
multicellular organismal agingGO:001025930.021
cellular chemical homeostasisGO:00550821800.021
lipid metabolic processGO:00066293810.021
cellular component morphogenesisGO:00329893140.020
cellular response to dna damage stimulusGO:00069743790.020
regulation of reactive oxygen species biosynthetic processGO:190342630.020
reproductionGO:0000003630.020
cell divisionGO:00513011680.020
regulation of cellular amine metabolic processGO:0033238110.020
regulation of apoptotic signaling pathwayGO:20012331750.020
ameboidal type cell migrationGO:00016671350.020
negative regulation of intracellular signal transductionGO:19025321830.020
cellular glucan metabolic processGO:0006073220.020
purine ribonucleoside metabolic processGO:00461284370.020
regulation of calcium ion transportGO:0051924790.020
cellular response to histamineGO:007142030.020
single organism reproductive processGO:0044702980.020
sequestering of metal ionGO:0051238240.019
regulation of protein ubiquitinationGO:0031396950.019
cerebellum developmentGO:002154920.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
ubiquitin dependent protein catabolic processGO:00065112060.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
posttranscriptional regulation of gene expressionGO:00106082130.019
nervous system developmentGO:00073992930.019
erk1 and erk2 cascadeGO:00703711040.019
regulation of ossificationGO:0030278580.019
protein maturationGO:00516042330.019
cellular amino acid metabolic processGO:00065201160.019
embryonic morphogenesisGO:0048598850.019
cellular response to oxygen containing compoundGO:19017012760.019
lung alveolus developmentGO:004828640.019
negative regulation of protein metabolic processGO:00512483910.018
regulation of cell motilityGO:20001452990.018
cellular response to organonitrogen compoundGO:00714171240.018
regulation of cell morphogenesisGO:00226041530.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
positive regulation of immune system processGO:00026842830.018
regulation of cellular amino acid metabolic processGO:000652160.018
establishment of protein localization to organelleGO:00725941720.018
establishment of protein localization to membraneGO:00901501210.018
myosin filament assemblyGO:003103420.017
regulation of membrane potentialGO:0042391950.017
sequestering of calcium ionGO:0051208170.017
cellular response to endogenous stimulusGO:00714953360.017
negative regulation of programmed cell deathGO:00430693210.017
negative regulation of cell differentiationGO:00455961710.017
intracellular mrna localizationGO:000829810.017
embryonic viscerocranium morphogenesisGO:004870310.017
organelle localizationGO:0051640840.017
lipid modificationGO:0030258840.017
cell cycle phase transitionGO:00447701730.017
regulation of homeostatic processGO:00328441210.017
dephosphorylationGO:00163112090.016
regulation of cellular response to growth factor stimulusGO:0090287760.016
developmental growthGO:0048589480.016
organic hydroxy compound metabolic processGO:19016151470.016
ribose phosphate biosynthetic processGO:0046390820.016
regulation of canonical wnt signaling pathwayGO:0060828880.016
response to organonitrogen compoundGO:00102431560.016
regulation of erk1 and erk2 cascadeGO:0070372990.016
regulation of cellular ketone metabolic processGO:0010565500.016
regulation of cell growthGO:00015581350.016
cellular amine metabolic processGO:0044106410.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
cellular amide metabolic processGO:0043603690.016
rna interferenceGO:001624640.016
negative regulation of cellular amine metabolic processGO:003323930.015
immune effector processGO:00022521590.015
calcium ion transportGO:00068161470.015
positive regulation of nucleoside metabolic processGO:00459791860.015
regulation of epithelial cell migrationGO:0010632930.015
innate immune responseGO:00450871780.015
regulation of wnt signaling pathwayGO:00301111230.015
chemical homeostasisGO:00488783060.015
metencephalon developmentGO:002203720.015
biological adhesionGO:00226103310.015
circadian behaviorGO:004851220.015
regulation of meiotic cell cycleGO:005144540.015
nucleoside triphosphate metabolic processGO:00091414220.015
signal transduction by phosphorylationGO:00230142970.015
embryo development ending in birth or egg hatchingGO:0009792340.015
skeletal system morphogenesisGO:0048705240.015
protein deubiquitinationGO:0016579790.015
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
cellular response to growth factor stimulusGO:00713631970.015
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.015
negative regulation of cell proliferationGO:00082852280.015
negative regulation of apoptotic processGO:00430663160.015
nuclear transportGO:00511691790.015
amine metabolic processGO:0009308440.015
regulation of cell activationGO:00508651250.014
response to biotic stimulusGO:00096072760.014
rhythmic behaviorGO:000762220.014
plasma membrane organizationGO:00070091150.014
regulation of purine nucleotide biosynthetic processGO:1900371500.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
ossificationGO:00015031210.014
multicellular organismal reproductive processGO:0048609400.014
response to oxygen containing compoundGO:19017003690.014
peptidyl serine phosphorylationGO:00181051010.014
positive regulation of cellular component movementGO:00512721810.014
associative learningGO:000830610.014
response to nitrogen compoundGO:19016981840.014
organelle assemblyGO:00709251760.014
secretionGO:00469032540.014
Rat
embryonic epithelial tube formationGO:000183840.014
positive regulation of cell sizeGO:004579330.014
modification dependent macromolecule catabolic processGO:00436322120.014
response to radiationGO:00093141510.014
lysosomal transportGO:0007041330.014
striated muscle myosin thick filament assemblyGO:007168820.014
monocarboxylic acid metabolic processGO:00327871850.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
positive regulation of transmembrane transportGO:0034764410.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
nuclear migrationGO:000709710.014
hemopoiesisGO:00300971800.014
mitotic cell cycle phase transitionGO:00447721620.013
regulation of peptidase activityGO:00525471800.013
secretion by cellGO:00329402260.013
Rat
regulation of nucleotide biosynthetic processGO:0030808500.013
response to endoplasmic reticulum stressGO:0034976490.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
protein localization to membraneGO:00726571600.013
chromatin modificationGO:00165682980.013
establishment of protein localization to plasma membraneGO:0090002680.013
regulation of cellular response to stressGO:00801352440.013
single organism cellular localizationGO:19025803320.013
regulation of cytoplasmic transportGO:19036491490.013
positive regulation of ion transportGO:0043270870.013
methylationGO:00322591060.013
cellular homeostasisGO:00197251960.013
positive regulation of cell cycle processGO:00900681060.013
defense responseGO:00069523150.013
cell morphogenesisGO:00009022960.013
regulation of proteasomal protein catabolic processGO:0061136870.013
cardiovascular system developmentGO:00723582620.013
regulation of cell migrationGO:00303342890.013
lipid biosynthetic processGO:00086101770.013
limbic system developmentGO:002176130.012
adult locomotory behaviorGO:000834410.012
regulation of protein maturationGO:19033171500.012
protein secretionGO:0009306980.012
forelimb morphogenesisGO:003513640.012
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.012
behavioral response to ethanolGO:004814920.012
regulation of transmembrane transportGO:00347621390.012
dna recombinationGO:0006310770.012
primary neural tube formationGO:001402030.012
protein homooligomerizationGO:00512601000.012
positive regulation of cell cycleGO:00457871400.012
microtubule based processGO:00070172100.012
cellular response to nitrogen compoundGO:19016991440.012
peptidyl serine modificationGO:00182091060.012
divalent metal ion transportGO:00708381520.012
epithelial cell proliferationGO:00506731280.012
endosome to lysosome transportGO:0008333210.012
regulation of neuron projection developmentGO:0010975570.012
melanin metabolic processGO:000658210.012
protein acylationGO:00435431380.012
regulation of purine nucleotide catabolic processGO:00331212050.012
neural tube closureGO:000184330.012
protein glycosylationGO:0006486620.012
Human
positive regulation of gtp catabolic processGO:00331261660.012
regulation of synaptic plasticityGO:004816730.012
sensory perceptionGO:00076001030.012
response to sucroseGO:000974410.012
neuron developmentGO:00486661130.012
negative regulation of cell deathGO:00605483450.012
monovalent inorganic cation transportGO:00156721280.012
anion transmembrane transportGO:0098656760.011
cation transmembrane transportGO:00986552380.011
cell projection organizationGO:00300302520.011
negative regulation of mitotic cell cycle phase transitionGO:1901991850.011
regulation of bindingGO:00510981110.011
regulation of sequestering of calcium ionGO:0051282410.011
blastocyst developmentGO:000182430.011
negative regulation of protein phosphorylationGO:00019331400.011
positive regulation of canonical wnt signaling pathwayGO:0090263330.011
positive regulation of ras gtpase activityGO:00323201170.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
dna replicationGO:00062601160.011
negative regulation of protein maturationGO:19033181420.011
mitochondrion distributionGO:004831130.011
response to growth factorGO:00708482050.011
positive regulation of ossificationGO:0045778320.011
regulation of intracellular transportGO:00323861950.011
purine containing compound biosynthetic processGO:0072522880.011
chemotaxisGO:00069351570.011
reactive oxygen species metabolic processGO:0072593750.011
regulation of cellular protein catabolic processGO:1903362960.011
actin mediated cell contractionGO:0070252120.011
glycerophospholipid metabolic processGO:0006650840.011
morphogenesis of an epitheliumGO:0002009600.011
embryonic camera type eye morphogenesisGO:004859620.011
divalent inorganic cation transportGO:00725111580.011
membrane invaginationGO:0010324100.011
cellular lipid catabolic processGO:0044242650.011
inorganic cation transmembrane transportGO:00986621940.011
wnt signaling pathwayGO:00160551560.011
cellular response to ammonium ionGO:007124240.011
digestive tract morphogenesisGO:0048546560.011
brain developmentGO:0007420970.011
alcohol metabolic processGO:00060661140.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
lipid localizationGO:00108761060.011
regulation of defense responseGO:00313471540.011
regulation of cyclic nucleotide biosynthetic processGO:0030802490.011
actin filament based movementGO:0030048170.010
taxisGO:00423301570.010
jnk cascadeGO:0007254800.010
positive regulation of adenylate cyclase activityGO:0045762120.010
negative regulation of dephosphorylationGO:0035305630.010
mitotic cell cycleGO:00002783260.010
actin polymerization or depolymerizationGO:0008154560.010
Human
regulation of dephosphorylationGO:0035303960.010
response to abiotic stimulusGO:00096283360.010
embryonic digestive tract morphogenesisGO:004855720.010
regulation of protein catabolic processGO:00421761550.010
positive regulation of wnt signaling pathwayGO:0030177540.010
cell type specific apoptotic processGO:00972851250.010
response to hormoneGO:00097251750.010
response to tumor necrosis factorGO:0034612760.010
cyclic nucleotide biosynthetic processGO:0009190610.010
gastrulation with mouth forming secondGO:000170210.010
regulation of establishment of protein localizationGO:00702012420.010
cell substrate adhesionGO:00315891320.010
eye photoreceptor cell differentiationGO:000175420.010
negative regulation of proteolysisGO:00458611320.010

ARFGEF2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.043
cancerDOID:1621670.043
bone diseaseDOID:0080001880.034
bone development diseaseDOID:0080006550.034
connective tissue diseaseDOID:651090.034
musculoskeletal system diseaseDOID:172230.034
organ system cancerDOID:00506861640.028
immune system diseaseDOID:29141550.027
endocrine gland cancerDOID:170260.022
central nervous system diseaseDOID:3311860.015
nervous system diseaseDOID:8634310.015
disease of metabolismDOID:00146672950.014
hematopoietic system diseaseDOID:741000.014
neurodegenerative diseaseDOID:12891020.012
sensory system diseaseDOID:00501552030.012
auditory system diseaseDOID:2742530.012
physical disorderDOID:0080015410.003
congenital nervous system abnormalityDOID:2490210.003