Homo sapiens

89 known processes

PIK3CG

phosphoinositide-3-kinase, catalytic, gamma polypeptide

(Aliases: PIK3,PI3CG,PI3Kgamma,PI3K)

PIK3CG biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071862070.327
lymphocyte activationGO:00466491330.283
leukocyte activationGO:00453211640.234
post embryonic developmentGO:000979120.118
neuromuscular junction developmentGO:000752830.112
regulation of cell activationGO:00508651250.110
purine ribonucleoside catabolic processGO:00461303980.104
signal transduction by phosphorylationGO:00230142970.101
positive regulation of hydrolase activityGO:00513453310.100
nucleoside phosphate catabolic processGO:19012924120.093
nucleotide catabolic processGO:00091664080.091
response to biotic stimulusGO:00096072760.090
immune responseGO:00069553070.089
cation transportGO:00068123310.086
nucleoside triphosphate catabolic processGO:00091433940.085
regulation of immune responseGO:00507762010.082
purine nucleotide catabolic processGO:00061954050.079
purine ribonucleoside metabolic processGO:00461284370.077
purine ribonucleotide catabolic processGO:00091544040.077
oogenesisGO:004847720.076
biological adhesionGO:00226103310.075
female gamete generationGO:000729220.074
purine nucleoside triphosphate catabolic processGO:00091463920.074
cellular response to growth factor stimulusGO:00713631970.073
b cell activationGO:0042113330.072
ribonucleotide catabolic processGO:00092614050.071
response to other organismGO:00517072610.071
purine nucleoside triphosphate metabolic processGO:00091444120.070
ribonucleoside triphosphate metabolic processGO:00091994120.069
regulation of response to external stimulusGO:00321012220.066
activation of immune responseGO:00022531140.066
cell adhesionGO:00071553250.066
positive regulation of cellular catabolic processGO:00313312840.063
positive regulation of kinase activityGO:00336742040.063
regulation of cellular amino acid metabolic processGO:000652160.062
response to external biotic stimulusGO:00432072610.061
positive regulation of phosphorylationGO:00423273940.059
cell activationGO:00017752130.059
positive regulation of mapk cascadeGO:00434101900.059
mapk cascadeGO:00001652880.059
lipid metabolic processGO:00066293810.058
immune response regulating signaling pathwayGO:0002764970.057
positive regulation of cellular amine metabolic processGO:003324070.057
lipid biosynthetic processGO:00086101770.055
immune response activating signal transductionGO:0002757900.055
gtp catabolic processGO:00061842370.054
system processGO:00030083490.054
cellular response to oxygen containing compoundGO:19017012760.053
positive regulation of cell activationGO:0050867810.052
amine metabolic processGO:0009308440.052
cellular lipid metabolic processGO:00442553030.051
purine ribonucleoside triphosphate catabolic processGO:00092073910.051
cell projection organizationGO:00300302520.050
regulation of locomotionGO:00400123290.050
positive regulation of transferase activityGO:00513472270.050
reactive oxygen species metabolic processGO:0072593750.048
regulation of synaptic plasticityGO:004816730.046
positive regulation of cell differentiationGO:00455972110.046
positive regulation of purine nucleotide metabolic processGO:19005442270.046
negative regulation of phosphorus metabolic processGO:00105632670.045
response to oxygen containing compoundGO:19017003690.045
ras protein signal transductionGO:0007265730.045
positive regulation of cell proliferationGO:00082843010.045
positive regulation of protein kinase activityGO:00458601900.044
nervous system developmentGO:00073992930.043
regulation of cell cycleGO:00517263930.043
organophosphate catabolic processGO:00464344300.043
glycerolipid metabolic processGO:00464861070.043
glycosyl compound catabolic processGO:19016584130.042
regulation of reactive oxygen species metabolic processGO:2000377410.042
cell developmentGO:00484683280.041
negative regulation of cell proliferationGO:00082852280.041
regulation of protein serine threonine kinase activityGO:00719001790.041
regulation of purine nucleotide metabolic processGO:19005422640.041
organophosphate biosynthetic processGO:00904071630.040
cytokine productionGO:00018162470.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.040
negative regulation of cellular amine metabolic processGO:003323930.039
cellular ketone metabolic processGO:0042180800.039
positive regulation of cellular amino acid metabolic processGO:004576430.039
positive regulation of cellular component organizationGO:00511303760.039
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.039
negative regulation of apoptotic processGO:00430663160.039
positive regulation of nucleotide metabolic processGO:00459812300.038
hematopoietic or lymphoid organ developmentGO:00485341860.038
regulation of immune effector processGO:0002697910.037
cation transmembrane transportGO:00986552380.037
inorganic cation transmembrane transportGO:00986621940.036
regulation of cellular component movementGO:00512703340.036
negative regulation of programmed cell deathGO:00430693210.036
organonitrogen compound biosynthetic processGO:19015662000.036
cellular response to endogenous stimulusGO:00714953360.036
neuron projection developmentGO:00311751060.035
regulation of cellular ketone metabolic processGO:0010565500.035
cellular amine metabolic processGO:0044106410.035
leukocyte proliferationGO:0070661740.035
negative regulation of phosphate metabolic processGO:00459362670.035
ion transmembrane transportGO:00342203380.035
regulation of neuronal synaptic plasticityGO:004816810.034
multicellular organismal agingGO:001025930.034
negative regulation of catalytic activityGO:00430863350.034
cellular response to external stimulusGO:00714961110.034
regulation of establishment of protein localizationGO:00702012420.033
positive regulation of lymphocyte activationGO:0051251730.033
mitotic cell cycleGO:00002783260.033
regulation of vesicle mediated transportGO:00606271300.033
cardiac muscle contractionGO:0060048340.032
dephosphorylationGO:00163112090.032
regulation of cellular amine metabolic processGO:0033238110.032
actin filament based processGO:00300292240.031
regulation of neuron differentiationGO:0045664700.031
inorganic ion transmembrane transportGO:00986602310.031
protein localization to organelleGO:00333652800.031
positive regulation of catabolic processGO:00098963100.031
regulation of purine nucleotide catabolic processGO:00331212050.031
segmentationGO:003528240.030
negative regulation of protein metabolic processGO:00512483910.030
sodium ion transmembrane transportGO:0035725590.030
small gtpase mediated signal transductionGO:0007264780.030
cellular response to dna damage stimulusGO:00069743790.030
vesicle mediated transportGO:00161923710.030
striated muscle contractionGO:0006941520.029
hemopoiesisGO:00300971800.029
carbohydrate derivative biosynthetic processGO:19011372070.029
cellular amino acid metabolic processGO:00065201160.029
single organism carbohydrate metabolic processGO:00447231930.029
positive regulation of defense responseGO:0031349870.028
regulation of cell projection organizationGO:00313441070.028
negative regulation of cell deathGO:00605483450.028
secretionGO:00469032540.028
regulation of defense responseGO:00313471540.028
regulation of nucleoside metabolic processGO:00091182090.028
regulation of nucleotide metabolic processGO:00061402690.027
locomotory behaviorGO:000762610.027
cytoplasmic transportGO:00164823790.027
positive regulation of purine nucleotide catabolic processGO:00331231850.027
response to bacteriumGO:00096171440.027
lipid modificationGO:0030258840.027
small molecule biosynthetic processGO:00442831570.027
positive regulation of immune system processGO:00026842830.027
stress activated protein kinase signaling cascadeGO:0031098940.027
positive regulation of developmental processGO:00510943140.027
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.027
wound healingGO:00420601150.026
growthGO:00400072020.026
response to virusGO:00096151260.026
establishment of protein localization to organelleGO:00725941720.026
regulation of humoral immune response mediated by circulating immunoglobulinGO:000292330.026
intracellular protein transportGO:00068862700.026
positive regulation of cell deathGO:00109422630.026
gtp metabolic processGO:00460392390.026
regulation of interferon beta biosynthetic processGO:004535740.026
positive regulation of protein phosphorylationGO:00019343130.025
negative regulation of cellular protein metabolic processGO:00322693530.025
cellular component morphogenesisGO:00329893140.025
divalent metal ion transportGO:00708381520.025
regulation of myeloid leukocyte mediated immunityGO:000288640.025
phospholipid metabolic processGO:0006644990.025
response to abiotic stimulusGO:00096283360.025
pattern recognition receptor signaling pathwayGO:0002221480.025
epithelial tube branching involved in lung morphogenesisGO:006044140.025
determination of adult lifespanGO:000834020.025
innate immune responseGO:00450871780.025
phagocytosis recognitionGO:000691030.025
phosphatidylinositol metabolic processGO:0046488530.025
regulation of anatomical structure morphogenesisGO:00226032860.025
glycerophospholipid metabolic processGO:0006650840.024
regulation of protein localizationGO:00328802960.024
rho protein signal transductionGO:0007266260.024
positive regulation of cytokine productionGO:00018191670.024
protein oligomerizationGO:00512591730.024
oocyte differentiationGO:000999420.024
negative regulation of protein modification processGO:00314002000.024
protein targetingGO:00066051870.024
chromatin modificationGO:00165682980.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
positive regulation of gtp catabolic processGO:00331261660.024
cell morphogenesisGO:00009022960.023
posttranscriptional regulation of gene expressionGO:00106082130.023
negative regulation of intracellular signal transductionGO:19025321830.023
activation of innate immune responseGO:0002218550.023
regulation of intracellular transportGO:00323861950.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
nuclear transportGO:00511691790.023
response to cytokineGO:00340972320.023
chromatin organizationGO:00063253510.023
defense response to virusGO:0051607710.023
regulation of transmembrane transporter activityGO:0022898740.023
positive regulation of innate immune responseGO:0045089790.023
regulation of cell adhesionGO:00301551660.023
neurological system processGO:00508771630.022
angiogenesisGO:00015251470.022
regulation of cell motilityGO:20001452990.022
regulation of mitotic cell cycleGO:00073461890.022
regulation of neurogenesisGO:0050767820.022
maintenance of locationGO:00512351120.022
positive regulation of locomotionGO:00400171860.022
interferon alpha biosynthetic processGO:004534940.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
memoryGO:000761330.022
positive regulation of cell projection organizationGO:0031346640.022
response to lipopolysaccharideGO:0032496700.022
positive regulation of programmed cell deathGO:00430682490.022
positive regulation of nucleoside metabolic processGO:00459791860.021
cell matrix adhesionGO:0007160850.021
regulation of cell migrationGO:00303342890.021
cellular response to abiotic stimulusGO:00712141170.021
regulation of protein transportGO:00512232130.021
nucleoside triphosphate metabolic processGO:00091414220.021
translationGO:00064121320.021
monocarboxylic acid metabolic processGO:00327871850.021
covalent chromatin modificationGO:00165692540.021
purine containing compound catabolic processGO:00725234110.021
detection of stimulusGO:0051606850.021
single organism cell adhesionGO:00986021790.021
innate immune response activating signal transductionGO:0002758480.021
cellular macromolecular complex assemblyGO:00346223240.021
nucleocytoplasmic transportGO:00069131760.021
regulation of cellular component biogenesisGO:00440872810.020
positive regulation of map kinase activityGO:0043406800.020
histone modificationGO:00165702510.020
positive regulation of organ growthGO:004662220.020
generation of neuronsGO:00486991520.020
cardiac muscle cell contractionGO:008600340.020
regulation of cell differentiationGO:00455953930.020
negative regulation of catabolic processGO:00098951040.020
immune response activating cell surface receptor signaling pathwayGO:0002429450.020
regulation of interferon alpha biosynthetic processGO:004535440.020
regulation of ion transportGO:00432691890.020
regulation of anatomical structure sizeGO:00900661010.020
autophagyGO:0006914880.020
cellular response to starvationGO:0009267580.020
complement activation alternative pathwayGO:000695710.019
regulation of ion transmembrane transporter activityGO:0032412720.019
glycosphingolipid biosynthetic processGO:000668830.019
muscle system processGO:0003012810.019
response to radiationGO:00093141510.019
cellular response to nutrient levelsGO:0031669690.019
lymphocyte homeostasisGO:000226040.019
leukocyte differentiationGO:0002521980.019
positive regulation of cell sizeGO:004579330.019
regulation of metal ion transportGO:00109591200.019
vasculature developmentGO:00019441810.019
guanosine containing compound catabolic processGO:19010692390.019
cellular response to lipidGO:00713961270.019
positive regulation of cell migrationGO:00303351720.019
ribonucleoside catabolic processGO:00424544060.019
regulation of transporter activityGO:0032409820.019
regulation of transmembrane transportGO:00347621390.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
cell fate determinationGO:000170930.018
lymphocyte proliferationGO:0046651700.018
oocyte developmentGO:004859910.018
regulation of proteolysisGO:00301622930.018
regulation of gtp catabolic processGO:00331241800.018
regulation of growthGO:00400081650.018
t cell differentiation in thymusGO:003307740.018
taxisGO:00423301570.018
neuron developmentGO:00486661130.018
apoptotic signaling pathwayGO:00971902680.018
adaptive immune responseGO:0002250490.018
ganglioside biosynthetic processGO:000157430.018
matingGO:000761810.018
cell substrate adhesionGO:00315891320.018
regulation of cellular component sizeGO:0032535820.018
compound eye developmentGO:004874910.018
positive regulation of leukocyte activationGO:0002696800.018
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.018
cellular macromolecule catabolic processGO:00442653800.018
mitotic cell cycle processGO:19030472860.018
salivary gland morphogenesisGO:000743540.018
regulation of leukocyte proliferationGO:0070663670.018
guanosine containing compound metabolic processGO:19010682440.018
nuclear importGO:00511701060.018
regulation of mapk cascadeGO:00434082620.018
detection of chemical stimulusGO:0009593550.018
positive regulation of transportGO:00510503360.018
protein autophosphorylationGO:00467771230.017
positive regulation of leukocyte proliferationGO:0070665480.017
regulation of ras protein signal transductionGO:00465781550.017
transmembrane transportGO:00550853990.017
neuron differentiationGO:00301821380.017
regulation of nervous system developmentGO:0051960880.017
antigen receptor mediated signaling pathwayGO:0050851380.017
immune effector processGO:00022521590.017
serotonin transportGO:000683730.017
negative regulation of transportGO:00510511760.017
protein kinase b signalingGO:0043491690.017
cell projection morphogenesisGO:00488581290.017
peptidyl tyrosine modificationGO:00182121700.017
oxidation reduction processGO:00551143960.017
protein localization to nucleusGO:00345041360.017
regulation of multi organism processGO:00439001570.017
negative regulation of phosphorylationGO:00423261740.017
single organism membrane organizationGO:00448022680.017
positive regulation of protein serine threonine kinase activityGO:00719021190.017
microtubule based processGO:00070172100.017
regulation of secretion by cellGO:19035301770.017
mononuclear cell proliferationGO:0032943710.017
regulation of translationGO:0006417890.017
blastoderm segmentationGO:000735020.017
membrane organizationGO:00610242920.016
carbohydrate metabolic processGO:00059752070.016
positive regulation of cellular component biogenesisGO:00440891580.016
regulation of autophagyGO:0010506520.016
purinergic nucleotide receptor signaling pathwayGO:003559040.016
negative regulation of hydrolase activityGO:00513461820.016
regulation of ion transmembrane transportGO:00347651320.016
associative learningGO:000830610.016
metal ion transportGO:00300012720.016
cell cell signalingGO:00072671550.016
blood coagulationGO:0007596760.016
morphogenesis of embryonic epitheliumGO:001633140.016
cell chemotaxisGO:00603261120.016
calcium ion transportGO:00068161470.016
actin filament based movementGO:0030048170.016
response to woundingGO:00096111680.016
regulation of cell developmentGO:00602841610.016
adult locomotory behaviorGO:000834410.016
neurogenesisGO:00220081690.016
blood circulationGO:00080151130.016
negative regulation of cellular catabolic processGO:0031330830.016
neuroblast proliferationGO:000740540.016
hindbrain developmentGO:003090230.015
regulation of cytokine biosynthetic processGO:0042035350.015
muscle contractionGO:0006936730.015
positive regulation of immunoglobulin mediated immune responseGO:000289140.015
single organism cellular localizationGO:19025803320.015
protein catabolic processGO:00301633250.015
organ formationGO:004864530.015
regulation of lymphocyte mediated immunityGO:0002706330.015
actin cytoskeleton organizationGO:00300362070.015
protein maturationGO:00516042330.015
protein modification by small protein conjugationGO:00324463420.015
response to oxidative stressGO:00069791210.015
cellular protein catabolic processGO:00442572610.015
regenerationGO:003109940.015
regulation of peptidase activityGO:00525471800.015
cellular response to extracellular stimulusGO:0031668720.015
protein importGO:00170381300.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
regulation of stress activated protein kinase signaling cascadeGO:0070302850.014
regulation of immunoglobulin productionGO:000263740.014
organic hydroxy compound metabolic processGO:19016151470.014
monovalent inorganic cation transportGO:00156721280.014
cell part morphogenesisGO:00329901370.014
regulation of body fluid levelsGO:0050878990.014
regulation of cellular response to stressGO:00801352440.014
anterior posterior axis specificationGO:000994820.014
regulation of mononuclear cell proliferationGO:0032944650.014
cell growthGO:00160491600.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
cellular response to diacyl bacterial lipopeptideGO:007172620.014
regulation of actin cytoskeleton organizationGO:00329561160.014
spermatid developmentGO:000728640.014
azole transportGO:004511740.014
regulation of transferase activityGO:00513383550.014
purine nucleoside catabolic processGO:00061523980.014
stem cell divisionGO:001714520.014
regulation of sodium ion transmembrane transporter activityGO:2000649170.014
metal ion homeostasisGO:00550651690.014
regulation of jnk cascadeGO:0046328730.014
regulation of cell cycle processGO:00105642660.014
head developmentGO:00603221080.014
negative regulation of response to external stimulusGO:0032102830.014
anatomical structure homeostasisGO:00602491000.014
epithelium developmentGO:00604292270.014
long term memoryGO:000761620.014
myeloid cell differentiationGO:00300991170.014
thymus developmentGO:004853830.014
negative regulation of proteolysisGO:00458611320.014
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.014
positive regulation of multi organism processGO:0043902560.014
peptidyl tyrosine phosphorylationGO:00181081700.013
regulation of actin filament based processGO:00329701410.013
regulation of response to biotic stimulusGO:0002831550.013
regulation of cytoskeleton organizationGO:00514931770.013
reactive oxygen species biosynthetic processGO:190340940.013
cellular amide metabolic processGO:0043603690.013
spermatid differentiationGO:004851540.013
response to nitrogen compoundGO:19016981840.013
sodium ion transportGO:0006814610.013
regulation of leukocyte mediated immunityGO:0002703380.013
organelle assemblyGO:00709251760.013
circulatory system developmentGO:00723592620.013
leukocyte migrationGO:00509001070.013
positive regulation of b cell activationGO:0050871170.013
regulation of nucleotide catabolic processGO:00308112050.013
regulation of secretionGO:00510461940.013
n glycan processingGO:000649130.013
visual behaviorGO:000763220.013
regulation of endopeptidase activityGO:00525481700.013
negative regulation of protein phosphorylationGO:00019331400.013
tripartite regional subdivisionGO:000735120.013
phosphatidylinositol 3 kinase signalingGO:0014065480.013
regulation of gtpase activityGO:00430871800.013
metencephalon developmentGO:002203720.013
fatty acid metabolic processGO:00066311150.013
organic hydroxy compound biosynthetic processGO:1901617710.013
regulation of protein maturationGO:19033171500.013
motor neuron axon guidanceGO:000804520.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
positive regulation of interferon gamma productionGO:0032729260.013
protein ubiquitinationGO:00165673140.013
single organismal cell cell adhesionGO:00163371480.013
regulation of protein processingGO:00706131500.013
negative regulation of protein processingGO:00109551420.013
regulation of ras gtpase activityGO:00323181280.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
neurotransmitter secretionGO:000726940.013
sequestering of metal ionGO:0051238240.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
multi organism cellular processGO:00447641560.013
nucleotide biosynthetic processGO:00091651090.013
behaviorGO:00076101120.013
response to starvationGO:0042594590.013
rhythmic behaviorGO:000762220.013
cellular response to lipopolysaccharideGO:0071222570.013
microtubule cytoskeleton organizationGO:00002261760.013
regulation of stress activated mapk cascadeGO:0032872840.013
cellular response to triacyl bacterial lipopeptideGO:007172720.013
circulatory system processGO:00030131130.013
positive regulation of lymphocyte proliferationGO:0050671460.013
negative regulation of developmental processGO:00510932470.013
cell cycle phase transitionGO:00447701730.013
b cell proliferationGO:0042100220.012
regulation of meiotic cell cycleGO:005144540.012
regulation of homeostatic processGO:00328441210.012
protein secretionGO:0009306980.012
positive regulation of cellular component movementGO:00512721810.012
regulation of wnt signaling pathwayGO:00301111230.012
single organism nuclear importGO:19025931040.012
regulation of endocytosisGO:0030100720.012
hemostasisGO:0007599760.012
regulation of cytokine secretionGO:0050707570.012
endomembrane system organizationGO:00102561960.012
response to growth factorGO:00708482050.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
phospholipid biosynthetic processGO:0008654440.012
positive regulation of protein complex assemblyGO:0031334860.012
positive regulation of immune effector processGO:0002699400.012
negative regulation of transferase activityGO:00513481240.012
regulation of intracellular protein transportGO:00331571230.012
wnt signaling pathwayGO:00160551560.012
response to hormoneGO:00097251750.012
specification of organ identityGO:001009230.012
response to axon injuryGO:004867810.012
regulation of hemostasisGO:1900046420.012
glycoprotein biosynthetic processGO:0009101910.012
calcium ion homeostasisGO:00550741220.012
negative regulation of cell cycleGO:00457861930.012
syncytium formation by plasma membrane fusionGO:000076820.012
cytokine metabolic processGO:0042107380.012
response to nutrient levelsGO:0031667810.012
regulation of rho gtpase activityGO:0032319660.012
anterior posterior axis specification embryoGO:000859520.012
peptide metabolic processGO:0006518510.012
myeloid leukocyte activationGO:0002274340.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of t cell activationGO:0050863770.012
circadian behaviorGO:004851220.012
inner ear morphogenesisGO:004247240.012
organic acid biosynthetic processGO:0016053970.012
regulation of b cell proliferationGO:0030888180.012
sequestering of calcium ionGO:0051208170.012
cellular metal ion homeostasisGO:00068751460.012
cellular response to nitrogen compoundGO:19016991440.012
positive regulation of neurogenesisGO:0050769490.012
regulation of protein kinase activityGO:00458592890.012
nucleoside phosphate biosynthetic processGO:19012931090.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of dna metabolic processGO:00510521530.012
extrinsic apoptotic signaling pathwayGO:00971911190.012
coagulationGO:0050817780.012
cellular response to organonitrogen compoundGO:00714171240.011
somitogenesisGO:000175620.011
post embryonic organ developmentGO:004856910.011
positive regulation of immunoglobulin productionGO:000263940.011
myoblast fusionGO:000752010.011

PIK3CG disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.024
sensory system diseaseDOID:00501552030.023
nervous system diseaseDOID:8634310.023
musculoskeletal system diseaseDOID:172230.021
eye and adnexa diseaseDOID:14921500.020
disease of cellular proliferationDOID:145661740.019
organ system cancerDOID:00506861640.019
cancerDOID:1621670.019
connective tissue diseaseDOID:651090.017
central nervous system diseaseDOID:3311860.016
eye diseaseDOID:56141490.014
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.012