Homo sapiens

18 known processes

ANAPC4

anaphase promoting complex subunit 4

(Aliases: APC4)

ANAPC4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein k11 linked ubiquitinationGO:0070979241.000
regulation of mitotic metaphase anaphase transitionGO:0030071261.000
protein polyubiquitinationGO:00002091101.000
protein ubiquitinationGO:00165673141.000
protein modification by small protein conjugationGO:00324463421.000
regulation of sister chromatid segregationGO:0033045271.000
regulation of mitotic sister chromatid separationGO:0010965271.000
mitotic sister chromatid separationGO:0051306181.000
regulation of proteasomal protein catabolic processGO:0061136871.000
positive regulation of metaphase anaphase transition of cell cycleGO:190210160.999
regulation of chromosome segregationGO:0051983440.999
regulation of mitosisGO:0007088630.999
metaphase anaphase transition of cell cycleGO:0044784210.998
chromosome separationGO:0051304230.996
metaphase anaphase transition of mitotic cell cycleGO:0007091210.994
regulation of proteolysisGO:00301622930.985
mitotic sister chromatid segregationGO:0000070530.981
positive regulation of mitosisGO:0045840250.981
regulation of cellular protein catabolic processGO:1903362960.976
proteolysis involved in cellular protein catabolic processGO:00516032440.971
regulation of nuclear divisionGO:0051783650.969
ubiquitin dependent protein catabolic processGO:00065112060.967
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.965
sister chromatid segregationGO:0000819540.964
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.962
regulation of cell divisionGO:00513021160.959
modification dependent protein catabolic processGO:00199412090.958
cellular macromolecule catabolic processGO:00442653800.952
cellular protein catabolic processGO:00442572610.951
mitotic cell cycle phase transitionGO:00447721620.948
chromosome segregationGO:00070591140.939
positive regulation of chromosome segregationGO:005198490.924
regulation of mitotic cell cycle phase transitionGO:19019901180.913
mitotic nuclear divisionGO:00070671190.899
regulation of metaphase anaphase transition of cell cycleGO:1902099260.896
organelle fissionGO:00482851490.895
negative regulation of mitotic sister chromatid separationGO:2000816170.893
negative regulation of proteolysisGO:00458611320.876
regulation of mitotic sister chromatid segregationGO:0033047270.859
mitotic cell cycle processGO:19030472860.856
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.838
modification dependent macromolecule catabolic processGO:00436322120.830
regulation of chromosome organizationGO:00330441030.814
female gamete generationGO:000729220.809
protein catabolic processGO:00301633250.799
positive regulation of protein catabolic processGO:0045732750.783
cell divisionGO:00513011680.782
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143720.762
regulation of cell cycle processGO:00105642660.762
oogenesisGO:004847720.754
microtubule polymerizationGO:0046785180.737
mitotic spindle assembly checkpointGO:0007094140.707
regulation of cell cycle phase transitionGO:19019871260.702
positive regulation of mitotic sister chromatid separationGO:190197060.657
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.653
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.648
activation of anaphase promoting complex activityGO:005148860.647
positive regulation of cellular protein catabolic processGO:1903364370.645
centromeric sister chromatid cohesionGO:007060130.644
nuclear divisionGO:00002801280.609
negative regulation of mitotic cell cycleGO:00459301020.605
positive regulation of cell divisionGO:0051781590.592
positive regulation of organelle organizationGO:00106381950.591
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.586
regulation of protein ubiquitinationGO:0031396950.586
mitotic cell cycleGO:00002783260.530
positive regulation of ubiquitin protein transferase activityGO:0051443180.507
mitotic spindle checkpointGO:0071174180.500
negative regulation of mitotic anaphase promoting complex activityGO:006056440.467
regulation of mitotic cell cycleGO:00073461890.464
regulation of protein processingGO:00706131500.455
negative regulation of protein maturationGO:19033181420.449
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.426
positive regulation of cell cycleGO:00457871400.423
regulation of cell cycleGO:00517263930.422
positive regulation of cellular catabolic processGO:00313312840.415
regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143960.405
positive regulation of protein ubiquitinationGO:0031398530.402
activation of mitotic anaphase promoting complex activityGO:000709220.399
cyclin catabolic processGO:000805460.358
negative regulation of mitotic cell cycle phase transitionGO:1901991850.358
spindle checkpointGO:0031577260.357
positive regulation of chromosome organizationGO:2001252410.356
negative regulation of chromosome segregationGO:0051985180.356
positive regulation of nuclear divisionGO:0051785270.305
spindle assembly checkpointGO:0071173170.285
positive regulation of mitotic metaphase anaphase transitionGO:004584260.282
positive regulation of proteolysisGO:00458621420.278
regulation of dna dependent dna replication initiationGO:003017430.263
negative regulation of cell cycle processGO:00109481210.245
negative regulation of protein processingGO:00109551420.245
negative regulation of organelle organizationGO:00106391260.241
regulation of protein maturationGO:19033171500.239
cell cycle phase transitionGO:00447701730.235
regulation of protein catabolic processGO:00421761550.229
central nervous system myelinationGO:002201010.212
negative regulation of meiotic cell cycleGO:005144720.209
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.179
dna replication initiationGO:000627060.164
proteasomal protein catabolic processGO:00104981760.161
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.160
cellular response to dna damage stimulusGO:00069743790.153
dna conformation changeGO:00711031130.146
meiotic nuclear divisionGO:0007126100.139
regulation of dna metabolic processGO:00510521530.131
microtubule cytoskeleton organizationGO:00002261760.125
regulation of cellular ketone metabolic processGO:0010565500.123
negative regulation of sister chromatid segregationGO:0033046170.121
positive regulation of cell cycle processGO:00900681060.117
protein polymerizationGO:0051258710.116
positive regulation of mitotic cell cycleGO:0045931600.116
meiosis iGO:000712740.116
sensory organ developmentGO:0007423520.110
negative regulation of catalytic activityGO:00430863350.103
negative regulation of protein metabolic processGO:00512483910.103
cardiac muscle tissue developmentGO:0048738390.101
positive regulation of catabolic processGO:00098963100.100
negative regulation of dendritic spine developmentGO:006100010.099
negative regulation of ubiquitin protein transferase activityGO:005144480.097
negative regulation of cellular protein catabolic processGO:1903363380.092
regulation of synaptic transmissionGO:0050804110.091
negative regulation of transferase activityGO:00513481240.090
negative regulation of protein phosphorylationGO:00019331400.086
organelle assemblyGO:00709251760.086
negative regulation of chromosome organizationGO:2001251480.085
dna replicationGO:00062601160.084
maintenance of locationGO:00512351120.082
mrna 3 end processingGO:0031124240.082
nervous system developmentGO:00073992930.082
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.078
positive regulation of mitotic cell cycle phase transitionGO:1901992190.073
oocyte developmentGO:004859910.073
reproductive system developmentGO:0061458560.072
Worm
negative regulation of cellular catabolic processGO:0031330830.070
embryo developmentGO:00097901230.065
Worm
cellular amine metabolic processGO:0044106410.064
gonad developmentGO:0008406340.064
Worm
regulation of cytoskeleton organizationGO:00514931770.064
negative regulation of programmed cell deathGO:00430693210.062
negative regulation of axonogenesisGO:005077140.061
oocyte differentiationGO:000999420.061
negative regulation of cell cycleGO:00457861930.061
negative regulation of proteasomal protein catabolic processGO:1901799320.060
negative regulation of developmental processGO:00510932470.060
rna processingGO:00063962550.059
positive regulation of proteasomal protein catabolic processGO:1901800350.056
anterior posterior axis specificationGO:000994820.056
Worm
organophosphate catabolic processGO:00464344300.055
nucleic acid phosphodiester bond hydrolysisGO:00903051020.054
negative regulation of protein modification processGO:00314002000.054
regulation of meiotic cell cycleGO:005144540.050
cell developmentGO:00484683280.049
negative regulation of dna metabolic processGO:0051053570.049
negative regulation of mitosisGO:0045839240.048
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.047
cytokinesisGO:0000910960.047
positive regulation of cellular amino acid metabolic processGO:004576430.047
regulation of transferase activityGO:00513383550.046
cytoskeleton dependent cytokinesisGO:0061640220.045
cellular ketone metabolic processGO:0042180800.044
compound eye developmentGO:004874910.042
negative regulation of cellular protein metabolic processGO:00322693530.042
negative regulation of excitatory postsynaptic membrane potentialGO:009039410.042
regulation of cell activationGO:00508651250.041
covalent chromatin modificationGO:00165692540.039
positive regulation of cellular component organizationGO:00511303760.038
regulation of protein modification by small protein conjugation or removalGO:19033201070.036
developmental process involved in reproductionGO:0003006660.035
Worm
negative regulation of cellular component organizationGO:00511292350.035
post embryonic developmentGO:000979120.034
negative regulation of mitotic sister chromatid segregationGO:0033048170.034
regulation of leukocyte activationGO:00026941150.034
histone modificationGO:00165702510.034
long term synaptic potentiationGO:006029110.033
leukocyte activation involved in immune responseGO:0002366300.033
immune responseGO:00069553070.032
regulation of lymphocyte activationGO:00512491030.032
circulatory system developmentGO:00723592620.032
regulation of cell cell adhesion mediated by cadherinGO:200004740.031
phospholipid dephosphorylationGO:0046839100.031
negative regulation of cell deathGO:00605483450.030
spindle organizationGO:0007051530.030
single organism reproductive processGO:0044702980.030
Worm
cellular amino acid metabolic processGO:00065201160.030
nuclear transportGO:00511691790.030
inositol phosphate dephosphorylationGO:004685540.030
regulation of cellular amine metabolic processGO:0033238110.030
mitotic cytokinesisGO:0000281190.030
cell cycle checkpointGO:00000751170.030
secondary metabolic processGO:0019748170.028
regulation of histone modificationGO:0031056470.028
protein localization to organelleGO:00333652800.027
amine metabolic processGO:0009308440.027
lymphocyte activationGO:00466491330.027
single organism carbohydrate metabolic processGO:00447231930.027
negative regulation of apoptotic processGO:00430663160.027
negative regulation of cell motilityGO:20001461040.026
generation of neuronsGO:00486991520.026
axon regenerationGO:003110310.025
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200006030.025
chromatin organizationGO:00063253510.025
regulation of cellular amino acid metabolic processGO:000652160.025
regulation of ubiquitin protein transferase activityGO:0051438280.024
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143640.024
negative regulation of hydrolase activityGO:00513461820.024
central nervous system neuron axonogenesisGO:002195530.023
regulation of meiosisGO:004002030.023
positive regulation of cellular amine metabolic processGO:003324070.023
dendrite developmentGO:0016358240.023
microtubule based processGO:00070172100.023
regulation of cell cycle checkpointGO:1901976210.023
regulation of dendrite developmentGO:0050773180.022
carbohydrate derivative biosynthetic processGO:19011372070.022
maintenance of protein location in cellGO:0032507560.022
negative regulation of dna replicationGO:0008156290.022
purine ribonucleoside metabolic processGO:00461284370.022
regulation of protein serine threonine kinase activityGO:00719001790.022
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of apoptotic signaling pathwayGO:20012331750.021
regulation of dna replicationGO:0006275680.021
receptor metabolic processGO:0043112810.021
positive regulation of cell proliferationGO:00082843010.021
neurogenesisGO:00220081690.021
negative regulation of catabolic processGO:00098951040.021
negative regulation of kinase activityGO:00336731060.021
microtubule anchoringGO:0034453240.020
apoptotic signaling pathwayGO:00971902680.020
presynaptic membrane organizationGO:009709030.020
cellular carbohydrate metabolic processGO:0044262840.019
regulation of intracellular transportGO:00323861950.019
endothelial cell migrationGO:0043542860.019
embryo development ending in birth or egg hatchingGO:0009792340.019
Worm
negative regulation of cell differentiationGO:00455961710.019
mitotic metaphase plate congressionGO:0007080140.019
protein alkylationGO:0008213740.018
dendritic spine organizationGO:009706140.018
protein glycosylationGO:0006486620.018
cellular protein complex assemblyGO:00436231880.018
myeloid leukocyte activationGO:0002274340.017
methylationGO:00322591060.017
macromolecule glycosylationGO:0043413630.017
negative regulation of dendrite developmentGO:200017150.017
canonical wnt signaling pathwayGO:00600701160.017
regulation of mrna processingGO:0050684480.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
response to abiotic stimulusGO:00096283360.017
neuron differentiationGO:00301821380.017
single organism cellular localizationGO:19025803320.017
regulation of protein localizationGO:00328802960.017
g1 s transition of mitotic cell cycleGO:0000082780.016
regulation of protein kinase activityGO:00458592890.016
meiotic cell cycle checkpointGO:003331310.016
negative regulation of protein ubiquitinationGO:0031397350.016
nucleoside catabolic processGO:00091644080.016
cell projection organizationGO:00300302520.016
actin filament organizationGO:00070151280.016
positive regulation of phosphorylationGO:00423273940.016
protein acylationGO:00435431380.016
spindle assemblyGO:0051225290.015
regulation of anatomical structure morphogenesisGO:00226032860.015
eye developmentGO:0001654420.015
vesicle mediated transportGO:00161923710.015
determination of adult lifespanGO:000834020.015
ribonucleoside catabolic processGO:00424544060.015
purine containing compound biosynthetic processGO:0072522880.015
positive regulation of transferase activityGO:00513472270.015
purine nucleoside catabolic processGO:00061523980.014
negative regulation of phosphorus metabolic processGO:00105632670.014
cilium assemblyGO:0042384630.014
regulation of wnt signaling pathwayGO:00301111230.014
negative regulation of phosphorylationGO:00423261740.014
meiotic cell cycle processGO:190304680.014
negative regulation of cell cycle phase transitionGO:1901988890.014
positive regulation of intracellular protein transportGO:0090316760.014
response to calcium ionGO:0051592460.013
mrna metabolic processGO:00160711750.013
mitotic cell cycle checkpointGO:0007093680.013
epithelial cell migrationGO:00106311190.013
purine ribonucleotide catabolic processGO:00091544040.013
negative regulation of synaptic transmissionGO:005080520.013
cardiovascular system developmentGO:00723582620.013
innate immune responseGO:00450871780.013
regulation of cellular component biogenesisGO:00440872810.013
regulation of vesicle mediated transportGO:00606271300.013
dna repairGO:00062811980.013
regulation of dna dependent dna replicationGO:0090329190.013
establishment of meiotic spindle localizationGO:005129520.013
multicellular organismal response to stressGO:003355510.013
regulation of response to external stimulusGO:00321012220.013
regulation of cellular response to stressGO:00801352440.012
reproductionGO:0000003630.012
Worm
regulation of nucleocytoplasmic transportGO:0046822980.012
chemotaxisGO:00069351570.012
male meiosisGO:000714010.012
genitalia developmentGO:0048806100.012
Worm
negative regulation of locomotionGO:00400131180.012
epithelium migrationGO:00901321190.012
sexual reproductionGO:0019953370.012
morphogenesis of a polarized epitheliumGO:000173830.012
transmission of nerve impulseGO:0019226110.012
phagocytosisGO:0006909420.012
regulation of neurogenesisGO:0050767820.012
cytokine productionGO:00018162470.012
regulation of lymphocyte mediated immunityGO:0002706330.012
head developmentGO:00603221080.012
somatic recombination of immunoglobulin gene segmentsGO:001644740.012
nucleotide excision repair dna incisionGO:003368370.012
convergent extensionGO:006002610.012
establishment of organelle localizationGO:0051656590.011
positive regulation of secretionGO:00510471160.011
regulation of phosphatase activityGO:0010921810.011
development of primary sexual characteristicsGO:0045137350.011
Worm
hematopoietic or lymphoid organ developmentGO:00485341860.011
regulation of cell migrationGO:00303342890.011
protein maturationGO:00516042330.011
regulation of t cell activationGO:0050863770.011
positive regulation of cell cycle phase transitionGO:1901989220.011
regulation of immunoglobulin productionGO:000263740.011
rostrocaudal neural tube patterningGO:002190310.011
negative regulation of dna dependent dna replicationGO:200010490.011
negative regulation of cellular component movementGO:00512711060.011
phosphatidylinositol dephosphorylationGO:004685670.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
cellular lipid metabolic processGO:00442553030.011
regulation of homeostatic processGO:00328441210.011
microtubule organizing center organizationGO:0031023620.011
carbohydrate metabolic processGO:00059752070.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
oocyte maturationGO:000155610.010
regulation of cell morphogenesisGO:00226041530.010
neural tube patterningGO:002153220.010
glycerophospholipid metabolic processGO:0006650840.010
negative regulation of cell divisionGO:0051782310.010
regulation of ligase activityGO:0051340290.010
neuroblast proliferationGO:000740540.010
cell cycle g1 s phase transitionGO:0044843800.010
rna phosphodiester bond hydrolysisGO:0090501350.010
maintenance of location in cellGO:0051651620.010
protein kinase b signalingGO:0043491690.010
hemopoiesisGO:00300971800.010
stem cell differentiationGO:0048863930.010
positive regulation of protein phosphorylationGO:00019343130.010

ANAPC4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.048
gastrointestinal system cancerDOID:3119520.048
disease of cellular proliferationDOID:145661740.048
cancerDOID:1621670.048
nervous system diseaseDOID:8634310.026
sensory system diseaseDOID:00501552030.026
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
central nervous system diseaseDOID:3311860.014
neurodegenerative diseaseDOID:12891020.014
endocrine gland cancerDOID:170260.013
reproductive organ cancerDOID:193230.013
male reproductive organ cancerDOID:3856160.013