Homo sapiens

251 known processes

CALR

calreticulin

(Aliases: cC1qR,RO,SSA,FLJ26680,CRT)

CALR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.863
Worm Fly
4 hydroxyproline metabolic processGO:001947150.632
cellular amine metabolic processGO:0044106410.496
response to abiotic stimulusGO:00096283360.434
Worm
protein foldingGO:0006457380.410
Rat
chemotaxisGO:00069351570.386
response to decreased oxygen levelsGO:0036293960.367
cellular amino acid metabolic processGO:00065201160.352
regulation of cellular amine metabolic processGO:0033238110.304
response to endoplasmic reticulum stressGO:0034976490.283
Worm
protein hydroxylationGO:001812690.274
regulation of cell migrationGO:00303342890.233
regulation of cellular amino acid metabolic processGO:000652160.186
epithelium developmentGO:00604292270.176
oxidation reduction processGO:00551143960.175
cell morphogenesisGO:00009022960.165
regulation of cellular ketone metabolic processGO:0010565500.147
cell death in response to oxidative stressGO:0036473290.124
positive regulation of cellular amine metabolic processGO:003324070.122
multicellular organismal agingGO:001025930.115
ion homeostasisGO:00508012300.114
endoplasmic reticulum unfolded protein responseGO:0030968160.109
Worm
positive regulation of cellular component movementGO:00512721810.106
cellular response to transforming growth factor beta stimulusGO:0071560940.100
cellular response to topologically incorrect proteinGO:0035967190.100
Worm
nervous system developmentGO:00073992930.098
taxisGO:00423301570.096
regulation of behaviorGO:0050795820.095
negative regulation of multicellular organismal processGO:00512413170.092
stem cell developmentGO:0048864690.091
negative regulation of developmental processGO:00510932470.091
neuron projection developmentGO:00311751060.090
cellular carbohydrate metabolic processGO:0044262840.088
symbiosis encompassing mutualism through parasitismGO:00444031560.087
cellular response to external stimulusGO:00714961110.086
negative regulation of cell differentiationGO:00455961710.085
regulation of multi organism processGO:00439001570.082
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.082
determination of adult lifespanGO:000834020.081
embryo developmentGO:00097901230.081
regulation of chemotaxisGO:0050920740.081
regulation of apoptotic signaling pathwayGO:20012331750.078
neuron differentiationGO:00301821380.077
regulation of locomotionGO:00400123290.077
cell projection organizationGO:00300302520.075
regulation of cell motilityGO:20001452990.074
dna repairGO:00062811980.073
cellular component morphogenesisGO:00329893140.073
cellular divalent inorganic cation homeostasisGO:00725031280.072
response to growth factorGO:00708482050.072
cellular response to dna damage stimulusGO:00069743790.070
regulation of protein localizationGO:00328802960.070
response to oxygen containing compoundGO:19017003690.070
Rat Worm
positive regulation of programmed cell deathGO:00430682490.068
negative regulation of apoptotic processGO:00430663160.067
regulation of peptidyl tyrosine phosphorylationGO:00507301080.067
response to oxidative stressGO:00069791210.067
endomembrane system organizationGO:00102561960.066
response to transforming growth factor betaGO:0071559940.065
cellular ketone metabolic processGO:0042180800.065
epidermis morphogenesisGO:004873030.065
cytoplasmic transportGO:00164823790.064
chromatin modificationGO:00165682980.064
chaperone mediated protein foldingGO:0061077130.063
Rat
male genitalia developmentGO:003053910.062
positive regulation of cellular amino acid metabolic processGO:004576430.061
transforming growth factor beta receptor signaling pathwayGO:0007179760.061
response to topologically incorrect proteinGO:0035966290.060
Worm
apoptotic signaling pathwayGO:00971902680.060
response to hypoxiaGO:0001666960.060
vesicle mediated transportGO:00161923710.059
Mouse
growthGO:00400072020.056
response to oxygen levelsGO:00704821000.055
positive regulation of phosphorylationGO:00423273940.055
negative regulation of programmed cell deathGO:00430693210.055
cellular homeostasisGO:00197251960.055
renal system developmentGO:0072001630.054
nucleotide catabolic processGO:00091664080.054
leukocyte activationGO:00453211640.054
peptidyl tyrosine modificationGO:00182121700.054
cytosolic calcium ion transportGO:0060401480.053
positive regulation of developmental processGO:00510943140.053
chordate embryonic developmentGO:0043009340.052
regulation of cell morphogenesisGO:00226041530.052
regulation of cell developmentGO:00602841610.051
tissue morphogenesisGO:0048729960.051
negative regulation of cell adhesionGO:0007162640.050
cell chemotaxisGO:00603261120.049
sequestering of calcium ionGO:0051208170.049
organ formationGO:004864530.049
generation of neuronsGO:00486991520.049
transmembrane transportGO:00550853990.049
cellular chemical homeostasisGO:00550821800.048
cellular carbohydrate catabolic processGO:0044275170.048
viral processGO:00160321460.047
anatomical structure formation involved in morphogenesisGO:00486462840.047
cellular modified amino acid metabolic processGO:0006575640.046
glycogen catabolic processGO:000598040.045
positive regulation of protein kinase activityGO:00458601900.045
membrane organizationGO:00610242920.045
system processGO:00030083490.043
Worm Fly
cation homeostasisGO:00550801890.043
regulation of proteolysisGO:00301622930.043
response to other organismGO:00517072610.043
cerebral cortex radially oriented cell migrationGO:002179910.043
mitotic cell cycle phase transitionGO:00447721620.042
regulation of sequestering of calcium ionGO:0051282410.042
positive regulation of protein phosphorylationGO:00019343130.041
single organism membrane organizationGO:00448022680.041
hindbrain developmentGO:003090230.041
regulation of growthGO:00400081650.040
cellular response to growth factor stimulusGO:00713631970.039
receptor mediated endocytosisGO:0006898840.039
ameboidal type cell migrationGO:00016671350.039
monocarboxylic acid metabolic processGO:00327871850.038
gland developmentGO:0048732480.038
cellular response to endogenous stimulusGO:00714953360.037
head developmentGO:00603221080.037
Fly
sequestering of metal ionGO:0051238240.037
divalent inorganic cation homeostasisGO:00725071360.036
metal ion homeostasisGO:00550651690.036
epidermis developmentGO:0008544590.036
carbohydrate metabolic processGO:00059752070.035
regulation of protein processingGO:00706131500.035
cell morphogenesis involved in differentiationGO:00009041440.034
positive regulation of cell deathGO:00109422630.033
cellular polysaccharide catabolic processGO:004424740.033
calcium ion transport into cytosolGO:0060402480.032
dna recombinationGO:0006310770.032
peptidyl tyrosine phosphorylationGO:00181081700.032
enzyme linked receptor protein signaling pathwayGO:00071673030.032
epithelium migrationGO:00901321190.031
intrinsic apoptotic signaling pathwayGO:00971931270.031
regulation of oxidative stress induced cell deathGO:1903201240.031
chemical homeostasisGO:00488783060.031
response to hormoneGO:00097251750.031
Rat
response to external biotic stimulusGO:00432072610.031
positive regulation of cellular component organizationGO:00511303760.031
viral gene expressionGO:0019080350.031
dephosphorylationGO:00163112090.031
actin filament based processGO:00300292240.031
Mouse
recombinational repairGO:0000725500.031
matingGO:000761810.030
epithelial cell migrationGO:00106311190.030
cell growthGO:00160491600.030
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.030
regulation of response to oxidative stressGO:1902882260.030
extrinsic apoptotic signaling pathwayGO:00971911190.030
regulation of cell adhesionGO:00301551660.029
blastocyst developmentGO:000182430.029
glycogen metabolic processGO:0005977220.029
negative regulation of cell projection organizationGO:0031345220.029
muscle organ developmentGO:0007517560.029
single organism carbohydrate catabolic processGO:0044724330.029
cellular response to oxygen containing compoundGO:19017012760.029
plasma membrane organizationGO:00070091150.029
rna processingGO:00063962550.029
viral life cycleGO:00190581320.028
skin developmentGO:0043588760.028
positive regulation of hydrolase activityGO:00513453310.028
regulation of nervous system developmentGO:0051960880.028
regulation of anatomical structure morphogenesisGO:00226032860.028
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.028
regulation of cellular component movementGO:00512703340.028
alpha amino acid metabolic processGO:1901605720.028
organophosphate catabolic processGO:00464344300.028
response to radiationGO:00093141510.028
er nucleus signaling pathwayGO:0006984230.027
Worm
regulation of homeostatic processGO:00328441210.027
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
behaviorGO:00076101120.027
regulation of bindingGO:00510981110.027
defense responseGO:00069523150.027
pericardium developmentGO:006003920.027
cell part morphogenesisGO:00329901370.027
divalent metal ion transportGO:00708381520.027
cell cycle phase transitionGO:00447701730.027
endothelial cell migrationGO:0043542860.027
protein acylationGO:00435431380.027
odontogenesisGO:0042476250.027
synaptic vesicle endocytosisGO:004848820.027
cellular metal ion homeostasisGO:00068751460.026
peptidyl proline modificationGO:0018208150.026
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.026
positive regulation of cytosolic calcium ion concentrationGO:0007204820.026
peptidyl lysine modificationGO:00182051440.026
carbohydrate catabolic processGO:0016052360.026
visual behaviorGO:000763220.026
regulation of sequence specific dna binding transcription factor activityGO:00510902110.026
positive regulation of apoptotic processGO:00430652460.026
extracellular structure organizationGO:0043062410.025
maintenance of locationGO:00512351120.025
negative regulation of cell deathGO:00605483450.025
cellular ion homeostasisGO:00068731680.025
cell activationGO:00017752130.025
double strand break repair via homologous recombinationGO:0000724500.025
regulation of cytoplasmic transportGO:19036491490.025
regulation of cellular response to oxidative stressGO:1900407260.025
protein modification by small protein conjugationGO:00324463420.025
purine nucleoside catabolic processGO:00061523980.025
vasculature developmentGO:00019441810.025
double strand break repairGO:00063021010.024
positive regulation of locomotionGO:00400171860.024
cellular response to hypoxiaGO:0071456510.024
positive regulation of cell migrationGO:00303351720.024
amine metabolic processGO:0009308440.024
establishment of protein localization to membraneGO:00901501210.024
memoryGO:000761330.023
regulation of cell growthGO:00015581350.023
monocyte activationGO:004211730.023
negative regulation of phosphate metabolic processGO:00459362670.023
i kappab kinase nf kappab signalingGO:00072491660.023
protein localization to plasma membraneGO:0072659930.023
endocytosisGO:00068971590.023
Mouse
interspecies interaction between organismsGO:00444191560.023
circulatory system processGO:00030131130.022
response to nitrogen compoundGO:19016981840.022
multicellular organismal homeostasisGO:0048871670.022
modulation by host of symbiont transcriptionGO:0052472200.022
actin filament organizationGO:00070151280.022
peptide transportGO:0015833740.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of leukocyte chemotaxisGO:0002688460.022
cellular response to oxygen levelsGO:0071453550.022
oocyte developmentGO:004859910.021
cellular macromolecule catabolic processGO:00442653800.021
posttranscriptional regulation of gene expressionGO:00106082130.021
Mouse Rat
neuromuscular junction developmentGO:000752830.021
morphogenesis of embryonic epitheliumGO:001633140.021
regulation of epithelial cell migrationGO:0010632930.021
regulation of axon guidanceGO:190266730.021
positive regulation of growthGO:0045927580.020
regulation of gene expression epigeneticGO:0040029730.020
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.020
positive regulation of embryonic developmentGO:004001960.020
calcium ion homeostasisGO:00550741220.020
convergent extensionGO:006002610.020
regulation of phosphoprotein phosphatase activityGO:0043666230.020
response to extracellular stimulusGO:0009991850.020
regulation of cellular response to stressGO:00801352440.019
leukocyte chemotaxisGO:0030595760.019
positive regulation of cell proliferationGO:00082843010.019
regulation of kinase activityGO:00435493140.019
cell projection assemblyGO:00300311260.019
negative regulation of cellular protein metabolic processGO:00322693530.019
Rat
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.019
organ morphogenesisGO:00098871470.019
Fly
response to nutrient levelsGO:0031667810.019
locomotory behaviorGO:000762610.019
Fly
neurological system processGO:00508771630.019
Fly
response to biotic stimulusGO:00096072760.019
mrna metabolic processGO:00160711750.019
neuron developmentGO:00486661130.019
stem cell differentiationGO:0048863930.018
generation of precursor metabolites and energyGO:0006091680.018
nucleoside phosphate catabolic processGO:19012924120.018
cellular response to nitrogen compoundGO:19016991440.018
response to metal ionGO:0010038840.018
Rat
connective tissue developmentGO:0061448390.018
embryonic epithelial tube formationGO:000183840.018
protein secretionGO:0009306980.018
sensory perception of smellGO:000760820.018
regulation of ion homeostasisGO:2000021730.018
negative regulation of protein maturationGO:19033181420.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.018
cell adhesionGO:00071553250.017
regulation of lymphocyte chemotaxisGO:1901623120.017
positive regulation of intracellular transportGO:00323881040.017
primary neural tube formationGO:001402030.017
negative regulation of protein metabolic processGO:00512483910.017
Rat
segmentationGO:003528240.017
cellular calcium ion homeostasisGO:00068741170.017
positive regulation of apoptotic signaling pathwayGO:2001235700.017
energy derivation by oxidation of organic compoundsGO:0015980430.017
protein oligomerizationGO:00512591730.017
negative regulation of cell developmentGO:0010721480.017
metencephalon developmentGO:002203720.017
regulation of response to external stimulusGO:00321012220.017
regulation of protein maturationGO:19033171500.017
divalent inorganic cation transportGO:00725111580.017
positive regulation of cell motilityGO:20001471770.017
regulation of phosphatase activityGO:0010921810.017
nitrogen compound transportGO:00717051910.016
cellular response to unfolded proteinGO:0034620160.016
Worm
positive regulation of transportGO:00510503360.016
Mouse
negative regulation of proteolysisGO:00458611320.016
central nervous system developmentGO:00074171230.016
Fly
cellular cation homeostasisGO:00300031630.016
g2 m transition of mitotic cell cycleGO:0000086410.016
positive regulation of protein transportGO:00512221350.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
single organism cellular localizationGO:19025803320.016
lipoprotein metabolic processGO:0042157420.016
regulation of dephosphorylationGO:0035303960.016
mitotic cell cycle processGO:19030472860.016
glycosyl compound catabolic processGO:19016584130.016
mrna processingGO:00063971330.016
regulation of intracellular transportGO:00323861950.015
negative regulation of neuron differentiationGO:0045665210.015
purine nucleotide catabolic processGO:00061954050.015
blood circulationGO:00080151130.015
cation transportGO:00068123310.015
membrane protein ectodomain proteolysisGO:0006509330.015
protein homooligomerizationGO:00512601000.015
cytosolic calcium ion homeostasisGO:0051480890.015
negative regulation of sequestering of calcium ionGO:0051283410.015
tissue homeostasisGO:0001894630.015
intracellular protein transportGO:00068862700.015
multi organism metabolic processGO:0044033410.015
positive regulation of ras gtpase activityGO:00323201170.015
mitotic cell cycleGO:00002783260.015
ras protein signal transductionGO:0007265730.015
positive regulation of organelle organizationGO:00106381950.015
anterior posterior axis specification embryoGO:000859520.015
cellular glucan metabolic processGO:0006073220.015
formation of primary germ layerGO:0001704420.015
regulation of cell cycleGO:00517263930.015
negative regulation of cellular component organizationGO:00511292350.015
biological adhesionGO:00226103310.015
regulation of cell cycle processGO:00105642660.015
Mouse
calcium ion transportGO:00068161470.015
detection of chemical stimulusGO:0009593550.015
viral genome replicationGO:0019079500.015
neural crest cell developmentGO:001403230.015
visual learningGO:000854210.015
cellular response to organonitrogen compoundGO:00714171240.015
trabecula morphogenesisGO:006138320.015
adult locomotory behaviorGO:000834410.014
regulation of establishment of protein localizationGO:00702012420.014
cellular response to oxidative stressGO:0034599850.014
sensory perception of chemical stimulusGO:0007606380.014
protein maturationGO:00516042330.014
long term memoryGO:000761620.014
cellular response to decreased oxygen levelsGO:0036294510.014
cell cell signalingGO:00072671550.014
cell developmentGO:00484683280.014
alcohol metabolic processGO:00060661140.014
cellular response to abiotic stimulusGO:00712141170.014
microtubule based processGO:00070172100.014
negative regulation of protein modification processGO:00314002000.014
covalent chromatin modificationGO:00165692540.014
negative regulation of growthGO:0045926970.014
chromatin assemblyGO:0031497610.014
translationGO:00064121320.014
Rat
motor neuron axon guidanceGO:000804520.014
response to axon injuryGO:004867810.014
positive regulation of developmental growthGO:0048639160.014
lipid catabolic processGO:0016042840.014
regulation of gtp catabolic processGO:00331241800.014
t cell activationGO:0042110990.014
regulation of leukocyte migrationGO:0002685630.014
anterior posterior axis specificationGO:000994820.014
protein ubiquitinationGO:00165673140.014
internal protein amino acid acetylationGO:00064751010.014
gastrulationGO:0007369510.013
regulation of collagen metabolic processGO:0010712150.013
neural tube formationGO:000184130.013
extracellular matrix organizationGO:0030198410.013
multi organism cellular processGO:00447641560.013
cellular response to extracellular stimulusGO:0031668720.013
regulation of mitotic cell cycleGO:00073461890.013
cytokine productionGO:00018162470.013
negative regulation of peptidase activityGO:0010466910.013
negative regulation of catalytic activityGO:00430863350.013
chromatin assembly or disassemblyGO:0006333780.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
immune responseGO:00069553070.013
female gamete generationGO:000729220.013
modification dependent protein catabolic processGO:00199412090.013
peripheral nervous system developmentGO:000742220.013
myeloid leukocyte activationGO:0002274340.013
negative regulation of homeostatic processGO:0032845590.013
secretion by cellGO:00329402260.013
regulation of neuron projection developmentGO:0010975570.013
muscle structure developmentGO:0061061980.013
Rat
reactive oxygen species biosynthetic processGO:190340940.013
response to fungusGO:000962040.013
spermatid differentiationGO:004851540.012
interaction with hostGO:0051701420.012
semaphorin plexin signaling pathwayGO:007152640.012
endodermal cell differentiationGO:0035987310.012
tissue migrationGO:00901301190.012
negative regulation of cellular catabolic processGO:0031330830.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.012
positive regulation of secretionGO:00510471160.012
regulation of metal ion transportGO:00109591200.012
positive regulation of ion transmembrane transporter activityGO:0032414290.012
regulation of defense responseGO:00313471540.012
negative regulation of protein processingGO:00109551420.012
receptor transactivationGO:003562440.012
regulation of proteasomal protein catabolic processGO:0061136870.012
regulation of collagen catabolic processGO:001071030.012
response to cytokineGO:00340972320.012
steroid metabolic processGO:0008202940.012
reproductionGO:0000003630.012
Mouse Rat Worm
regenerationGO:003109940.012
purine ribonucleoside metabolic processGO:00461284370.012
positive regulation of cytoplasmic transportGO:1903651820.012
regulation of protein kinase activityGO:00458592890.012
regulation of viral processGO:00507921030.012
negative regulation of cell growthGO:0030308830.012
histone acetylationGO:0016573930.012
release of sequestered calcium ion into cytosolGO:0051209410.012
internal peptidyl lysine acetylationGO:0018393970.012
single organism carbohydrate metabolic processGO:00447231930.011
collateral sproutingGO:004866820.011
positive regulation of nucleotide metabolic processGO:00459812300.011
inorganic cation transmembrane transportGO:00986621940.011
modulation by host of viral transcriptionGO:0043921200.011
positive regulation of secretion by cellGO:19035321080.011
multicellular organism reproductionGO:0032504420.011
Rat Worm
small gtpase mediated signal transductionGO:0007264780.011
ribonucleotide catabolic processGO:00092614050.011
cell fate determinationGO:000170930.011
detection of stimulusGO:0051606850.011
actin mediated cell contractionGO:0070252120.011
cell projection morphogenesisGO:00488581290.011
cell cycle g2 m phase transitionGO:0044839430.011
striated muscle myosin thick filament assemblyGO:007168820.011
positive regulation of intracellular protein transportGO:0090316760.011
regulation of cellular protein catabolic processGO:1903362960.011
positive regulation of systemic arterial blood pressureGO:000308420.011
de novo protein foldingGO:000645820.011
regulation of protein stabilityGO:0031647870.011
Mouse
nucleoside monophosphate metabolic processGO:00091231910.011
positive regulation of protein secretionGO:0050714600.011
positive regulation of blood pressureGO:004577730.011
protein catabolic processGO:00301633250.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
digestive tract morphogenesisGO:0048546560.011
regulation of cell shapeGO:0008360480.010
endoderm developmentGO:0007492330.010
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817380.010
regulation of calcium ion transmembrane transporter activityGO:1901019280.010
positive regulation of catabolic processGO:00098963100.010
cell substrate junction assemblyGO:0007044350.010
Worm
purine ribonucleoside triphosphate metabolic processGO:00092054110.010
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.010
establishment of tissue polarityGO:000716430.010
post embryonic organ developmentGO:004856910.010
Fly
positive regulation of nucleotide catabolic processGO:00308131850.010
neural crest cell migrationGO:000175520.010
establishment of planar polarityGO:000173630.010
regulation of nucleoside metabolic processGO:00091182090.010
regulation of cellular component biogenesisGO:00440872810.010
positive regulation of leukocyte migrationGO:0002687460.010
lipid metabolic processGO:00066293810.010
oocyte differentiationGO:000999420.010

CALR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:651090.210
musculoskeletal system diseaseDOID:172230.210
Human
bone development diseaseDOID:0080006550.086
osteogenesis imperfectaDOID:12347130.086
bone diseaseDOID:0080001880.086
osteochondrodysplasiaDOID:2256350.086
nervous system diseaseDOID:8634310.063
central nervous system diseaseDOID:3311860.063
neurodegenerative diseaseDOID:12891020.063
urinary system diseaseDOID:18400.041
kidney diseaseDOID:557360.041
disease of mental healthDOID:150700.029
disease of cellular proliferationDOID:145661740.028
cancerDOID:1621670.028
organ system cancerDOID:00506861640.028
disease of metabolismDOID:00146672950.028
immune system diseaseDOID:29141550.021
dementiaDOID:1307190.020
cognitive disorderDOID:1561290.020
primary immunodeficiency diseaseDOID:612360.019
cardiovascular system diseaseDOID:12871060.019
Human
inherited metabolic disorderDOID:6552420.015
heart diseaseDOID:114680.013
Human
alzheimer s diseaseDOID:10652160.011
tauopathyDOID:680160.011
immune system cancerDOID:0060083360.004
hematologic cancerDOID:2531360.003
bone marrow cancerDOID:4960100.001
myelomaDOID:007000470.001
myelofibrosisDOID:497140.001
chronic myeloproliferative diseaseDOID:222630.000
hemorrhagic thrombocythemiaDOID:222430.000