Homo sapiens

22 known processes

PIP4K2B

phosphatidylinositol-5-phosphate 4-kinase, type II, beta

(Aliases: PIP5K2B,PI5P4KB,PIP5KIIbeta,PIP5KIIB)

PIP4K2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
artery smooth muscle contractionGO:001482430.210
tonic smooth muscle contractionGO:001482030.133
protein ubiquitinationGO:00165673140.093
nucleoside triphosphate metabolic processGO:00091414220.079
negative regulation of locomotionGO:00400131180.070
post embryonic developmentGO:000979120.068
positive regulation of acrosome reactionGO:200034440.068
positive regulation of developmental processGO:00510943140.067
Fly
regulation of cell cycleGO:00517263930.067
multicellular organismal agingGO:001025930.065
cellular protein catabolic processGO:00442572610.065
cellular macromolecule catabolic processGO:00442653800.064
regulation of acrosome reactionGO:006004640.062
glycosyl compound catabolic processGO:19016584130.062
cell adhesionGO:00071553250.060
Fly
biological adhesionGO:00226103310.056
Fly
receptor guanylyl cyclase signaling pathwayGO:000716850.055
negative regulation of protein metabolic processGO:00512483910.054
protein catabolic processGO:00301633250.053
negative regulation of cellular protein metabolic processGO:00322693530.053
protein modification by small protein conjugationGO:00324463420.053
organophosphate catabolic processGO:00464344300.052
purine ribonucleoside triphosphate catabolic processGO:00092073910.051
proteasomal protein catabolic processGO:00104981760.049
ribonucleoside catabolic processGO:00424544060.044
small gtpase mediated signal transductionGO:0007264780.043
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.042
negative regulation of protein modification processGO:00314002000.041
cell type specific apoptotic processGO:00972851250.041
luteolysisGO:000155430.040
positive regulation of catabolic processGO:00098963100.040
purine ribonucleoside triphosphate metabolic processGO:00092054110.040
modification dependent macromolecule catabolic processGO:00436322120.040
signal transduction by phosphorylationGO:00230142970.040
ras protein signal transductionGO:0007265730.039
cellular component morphogenesisGO:00329893140.039
Fly
chromatin organizationGO:00063253510.039
mitotic cell cycle processGO:19030472860.039
regulation of transferase activityGO:00513383550.038
internal protein amino acid acetylationGO:00064751010.038
regulation of cell cycle processGO:00105642660.037
defense responseGO:00069523150.037
regulation of sequence specific dna binding transcription factor activityGO:00510902110.037
ribonucleoside triphosphate catabolic processGO:00092033910.036
purine containing compound catabolic processGO:00725234110.036
positive regulation of cellular component organizationGO:00511303760.036
regulation of cellular ketone metabolic processGO:0010565500.036
positive regulation of cellular catabolic processGO:00313312840.036
regulation of apoptotic signaling pathwayGO:20012331750.036
positive regulation of gtp catabolic processGO:00331261660.035
single organism membrane organizationGO:00448022680.035
proteolysis involved in cellular protein catabolic processGO:00516032440.034
mitotic cell cycleGO:00002783260.034
regulation of locomotionGO:00400123290.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
chemical homeostasisGO:00488783060.033
morphogenesis of embryonic epitheliumGO:001633140.033
ribonucleotide catabolic processGO:00092614050.032
positive regulation of nucleoside metabolic processGO:00459791860.032
nervous system developmentGO:00073992930.032
cellular amino acid metabolic processGO:00065201160.032
rho protein signal transductionGO:0007266260.032
regulation of cellular component movementGO:00512703340.032
regulation of cell differentiationGO:00455953930.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
apoptotic signaling pathwayGO:00971902680.032
nucleoside catabolic processGO:00091644080.031
negative regulation of cell cycleGO:00457861930.031
regulation of protein catabolic processGO:00421761550.031
cell morphogenesisGO:00009022960.031
Fly
positive regulation of cell deathGO:00109422630.031
cytoplasmic transportGO:00164823790.030
regulation of kinase activityGO:00435493140.030
nucleotide catabolic processGO:00091664080.030
nucleoside triphosphate catabolic processGO:00091433940.030
regulation of cell motilityGO:20001452990.030
positive regulation of transportGO:00510503360.030
negative regulation of phosphorus metabolic processGO:00105632670.030
cellular ketone metabolic processGO:0042180800.030
covalent chromatin modificationGO:00165692540.030
regulation of mitotic cell cycleGO:00073461890.030
regulation of cell adhesionGO:00301551660.029
actin cytoskeleton organizationGO:00300362070.029
Fly
regulation of establishment of protein localizationGO:00702012420.029
regulation of cellular response to stressGO:00801352440.029
regulation of anatomical structure morphogenesisGO:00226032860.029
Fly
regulation of purine nucleotide metabolic processGO:19005422640.029
regulation of protein kinase activityGO:00458592890.029
positive regulation of programmed cell deathGO:00430682490.029
purine ribonucleoside metabolic processGO:00461284370.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
modification dependent protein catabolic processGO:00199412090.028
positive regulation of response to external stimulusGO:0032103880.028
cell growthGO:00160491600.027
Fly
positive regulation of phosphorylationGO:00423273940.027
gtp metabolic processGO:00460392390.027
peptidyl lysine modificationGO:00182051440.027
regulation of secretion by cellGO:19035301770.027
guanosine containing compound catabolic processGO:19010692390.027
vesicle mediated transportGO:00161923710.026
positive regulation of gtpase activityGO:00435471660.026
purine nucleoside catabolic processGO:00061523980.026
positive regulation of apoptotic processGO:00430652460.026
response to oxygen containing compoundGO:19017003690.026
startle responseGO:000196430.026
determination of adult lifespanGO:000834020.026
regulation of cellular amino acid metabolic processGO:000652160.025
chromatin modificationGO:00165682980.025
positive regulation of purine nucleotide metabolic processGO:19005442270.025
posttranscriptional regulation of gene expressionGO:00106082130.025
ubiquitin dependent protein catabolic processGO:00065112060.025
histone modificationGO:00165702510.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
positive regulation of hydrolase activityGO:00513453310.024
regulation of purine nucleotide catabolic processGO:00331212050.024
positive regulation of reactive oxygen species biosynthetic processGO:190342820.024
regenerationGO:003109940.024
neuromuscular junction developmentGO:000752830.024
response to abiotic stimulusGO:00096283360.024
regulation of ras gtpase activityGO:00323181280.024
segmentationGO:003528240.024
cell projection organizationGO:00300302520.024
guanosine containing compound metabolic processGO:19010682440.024
negative regulation of axonogenesisGO:005077140.023
positive regulation of cell differentiationGO:00455972110.023
response to biotic stimulusGO:00096072760.023
intracellular protein transportGO:00068862700.023
cell substrate adhesionGO:00315891320.022
regulation of cellular amine metabolic processGO:0033238110.022
regulation of gtp catabolic processGO:00331241800.022
regulation of synaptic plasticityGO:004816730.022
response to oxidative stressGO:00069791210.022
locomotory behaviorGO:000762610.022
cellular homeostasisGO:00197251960.022
membrane organizationGO:00610242920.022
positive regulation of purine nucleotide catabolic processGO:00331231850.022
intrinsic apoptotic signaling pathwayGO:00971931270.022
protein localization to organelleGO:00333652800.022
regulation of cytoskeleton organizationGO:00514931770.022
positive regulation of keratinocyte migrationGO:005154940.022
negative regulation of multicellular organismal processGO:00512413170.022
regulation of cell migrationGO:00303342890.022
cellular divalent inorganic cation homeostasisGO:00725031280.022
cellular amine metabolic processGO:0044106410.021
regulation of protein ubiquitinationGO:0031396950.021
negative regulation of organelle organizationGO:00106391260.021
stress activated protein kinase signaling cascadeGO:0031098940.021
nucleoside phosphate catabolic processGO:19012924120.021
purine ribonucleotide catabolic processGO:00091544040.021
cell divisionGO:00513011680.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
positive regulation of secretion by cellGO:19035321080.021
regulation of ras protein signal transductionGO:00465781550.021
leukocyte migrationGO:00509001070.021
positive regulation of organelle organizationGO:00106381950.021
protein acetylationGO:00064731160.021
organophosphate biosynthetic processGO:00904071630.021
protein targetingGO:00066051870.020
negative regulation of catalytic activityGO:00430863350.020
response to inorganic substanceGO:00100351270.020
positive regulation of nucleotide metabolic processGO:00459812300.020
response to oxygen levelsGO:00704821000.020
regulation of gtpase activityGO:00430871800.020
cellular response to endogenous stimulusGO:00714953360.020
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.020
cellular lipid metabolic processGO:00442553030.020
rna interferenceGO:001624640.020
neural tube formationGO:000184130.020
ectoderm developmentGO:000739830.020
regulation of proteolysisGO:00301622930.020
cell cycle phase transitionGO:00447701730.020
protein acylationGO:00435431380.020
neuron projection developmentGO:00311751060.019
positive regulation of protein phosphorylationGO:00019343130.019
regulation of keratinocyte migrationGO:005154740.019
positive regulation of kinase activityGO:00336742040.019
purine nucleotide catabolic processGO:00061954050.019
positive regulation of chemotaxisGO:0050921570.019
regulation of proteasomal protein catabolic processGO:0061136870.019
protein homooligomerizationGO:00512601000.019
nucleoside monophosphate metabolic processGO:00091231910.019
amine metabolic processGO:0009308440.019
immune responseGO:00069553070.019
regulation of nucleoside metabolic processGO:00091182090.019
positive regulation of protein kinase activityGO:00458601900.018
regulation of protein transportGO:00512232130.018
oocyte developmentGO:004859910.018
regulation of vesicle mediated transportGO:00606271300.018
regulation of nucleotide metabolic processGO:00061402690.018
positive regulation of cellular amine metabolic processGO:003324070.018
interspecies interaction between organismsGO:00444191560.018
internal peptidyl lysine acetylationGO:0018393970.018
negative regulation of protein phosphorylationGO:00019331400.018
single organism cellular localizationGO:19025803320.018
cell activationGO:00017752130.018
neurological system processGO:00508771630.018
negative regulation of cellular component movementGO:00512711060.018
regulation of protein localizationGO:00328802960.018
organelle fissionGO:00482851490.018
innate immune responseGO:00450871780.017
negative regulation of phosphate metabolic processGO:00459362670.017
transmembrane transportGO:00550853990.017
system processGO:00030083490.017
negative regulation of growthGO:0045926970.017
cellular response to dna damage stimulusGO:00069743790.017
lipid biosynthetic processGO:00086101770.017
positive regulation of lymphocyte migrationGO:2000403160.017
protein maturationGO:00516042330.017
anterior posterior axis specificationGO:000994820.017
negative regulation of cell growthGO:0030308830.017
multi organism cellular processGO:00447641560.017
oocyte differentiationGO:000999420.017
g protein coupled receptor signaling pathwayGO:00071862070.017
negative regulation of cell motilityGO:20001461040.017
cellular response to external stimulusGO:00714961110.017
muscle system processGO:0003012810.017
regulation of secretionGO:00510461940.017
nuclear divisionGO:00002801280.017
negative regulation of developmental processGO:00510932470.016
positive regulation of immune system processGO:00026842830.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.016
regulation of protein serine threonine kinase activityGO:00719001790.016
ion homeostasisGO:00508012300.016
inorganic ion transmembrane transportGO:00986602310.016
neuron differentiationGO:00301821380.016
small molecule biosynthetic processGO:00442831570.016
response to external biotic stimulusGO:00432072610.016
secretion by cellGO:00329402260.016
regulation of actin filament based processGO:00329701410.016
anterior posterior axis specification embryoGO:000859520.016
metal ion transportGO:00300012720.016
peptidyl lysine acetylationGO:00183941010.016
regulation of multi organism processGO:00439001570.016
lipid metabolic processGO:00066293810.016
positive regulation of nucleotide catabolic processGO:00308131850.016
regulation of cellular component biogenesisGO:00440872810.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
negative regulation of cell migrationGO:00303361020.016
response to cytokineGO:00340972320.016
gtp catabolic processGO:00061842370.016
cytokinesisGO:0000910960.016
memoryGO:000761330.016
regulation of meiosisGO:004002030.016
cellular protein complex assemblyGO:00436231880.016
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720520.016
positive regulation of mapk cascadeGO:00434101900.015
cellular response to nutrient levelsGO:0031669690.015
maintenance of locationGO:00512351120.015
response to lipidGO:00339932060.015
spemann organizer formationGO:006006110.015
neurogenesisGO:00220081690.015
hindbrain developmentGO:003090230.015
regulation of cell growthGO:00015581350.015
Fly
positive regulation of cell migrationGO:00303351720.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
g1 s transition of mitotic cell cycleGO:0000082780.015
response to hormoneGO:00097251750.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
photoreceptor cell differentiationGO:004653020.015
protein oligomerizationGO:00512591730.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.015
divalent inorganic cation transportGO:00725111580.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of meiotic cell cycleGO:005144540.015
histone h3 acetylationGO:0043966450.015
inorganic cation transmembrane transportGO:00986621940.015
monocyte activationGO:004211730.015
metal ion homeostasisGO:00550651690.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of cell proliferationGO:00082843010.015
forebrain neuron differentiationGO:002187930.015
blastoderm segmentationGO:000735020.015
motor neuron axon guidanceGO:000804520.015
endosomal transportGO:00161971290.014
negative regulation of cell proliferationGO:00082852280.014
axis elongationGO:000340140.014
nucleotide biosynthetic processGO:00091651090.014
positive regulation of cellular component movementGO:00512721810.014
response to bacteriumGO:00096171440.014
cerebellum developmentGO:002154920.014
positive regulation of ras gtpase activityGO:00323201170.014
purine ribonucleoside catabolic processGO:00461303980.014
regulation of cellular protein catabolic processGO:1903362960.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
histone h4 k5 acetylationGO:0043981150.014
regulation of syncytium formation by plasma membrane fusionGO:006014220.014
defense response to other organismGO:00985421290.014
establishment of protein localization to membraneGO:00901501210.014
regulation of nucleotide catabolic processGO:00308112050.014
regulation of cytokine productionGO:00018172320.014
positive regulation of proteolysisGO:00458621420.014
positive regulation of locomotionGO:00400171860.014
cell developmentGO:00484683280.014
regulation of ion transportGO:00432691890.014
protein localization to membraneGO:00726571600.014
response to endoplasmic reticulum stressGO:0034976490.014
viral processGO:00160321460.014
ion transmembrane transportGO:00342203380.014
regulation of mitochondrion organizationGO:0010821540.014
organonitrogen compound biosynthetic processGO:19015662000.014
female gamete generationGO:000729220.013
purine containing compound biosynthetic processGO:0072522880.013
mitotic cell cycle phase transitionGO:00447721620.013
nucleoside phosphate biosynthetic processGO:19012931090.013
epithelial cell proliferationGO:00506731280.013
oxidation reduction processGO:00551143960.013
tissue migrationGO:00901301190.013
cell morphogenesis involved in differentiationGO:00009041440.013
reactive oxygen species metabolic processGO:0072593750.013
response to metal ionGO:0010038840.013
leukocyte activationGO:00453211640.013
atp metabolic processGO:00460341760.013
cellular macromolecular complex assemblyGO:00346223240.013
positive regulation of secretionGO:00510471160.013
cellular chemical homeostasisGO:00550821800.013
neuron developmentGO:00486661130.013
regulation of cell morphogenesisGO:00226041530.013
Fly
endocytosisGO:00068971590.013
negative regulation of hydrolase activityGO:00513461820.013
cation transmembrane transportGO:00986552380.013
mitochondrion organizationGO:00070051560.013
cellular metal ion homeostasisGO:00068751460.013
negative regulation of programmed cell deathGO:00430693210.013
ossificationGO:00015031210.013
single organism cell adhesionGO:00986021790.013
oogenesisGO:004847720.013
negative regulation of catabolic processGO:00098951040.013
cytokine productionGO:00018162470.013
metencephalon developmentGO:002203720.013
actin filament based processGO:00300292240.013
Fly
positive regulation of protein catabolic processGO:0045732750.012
positive regulation of cytokine productionGO:00018191670.012
cellular response to decreased oxygen levelsGO:0036294510.012
tissue regenerationGO:004224630.012
microtubule based processGO:00070172100.012
cell chemotaxisGO:00603261120.012
negative regulation of intracellular signal transductionGO:19025321830.012
regulation of membrane potentialGO:0042391950.012
epithelium developmentGO:00604292270.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
cellular response to lipidGO:00713961270.012
embryonic epithelial tube formationGO:000183840.012
spermatid differentiationGO:004851540.012
cellular response to glucocorticoid stimulusGO:007138540.012
negative regulation of cell cycle phase transitionGO:1901988890.012
receptor transactivationGO:003562440.012
rab protein signal transductionGO:003248240.012
regulation of anatomical structure sizeGO:00900661010.012
convergent extensionGO:006002610.012
cell projection morphogenesisGO:00488581290.012
regulation of cell cycle phase transitionGO:19019871260.012
long term memoryGO:000761620.012
negative regulation of synaptic transmissionGO:005080520.012
nitrogen compound transportGO:00717051910.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
wnt signaling pathway calcium modulating pathwayGO:000722320.012
response to fungusGO:000962040.012
response to nitrogen compoundGO:19016981840.012
single organism reproductive processGO:0044702980.012
rhythmic behaviorGO:000762220.012
regulation of protein processingGO:00706131500.012
response to decreased oxygen levelsGO:0036293960.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
establishment of protein localization to organelleGO:00725941720.012
leukocyte chemotaxisGO:0030595760.011
somatic stem cell divisionGO:004810310.011
regulation of microtubule based processGO:0032886740.011
negative regulation of protein kinase activityGO:0006469980.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
organelle assemblyGO:00709251760.011
apoptotic mitochondrial changesGO:0008637570.011
positive regulation of cell motilityGO:20001471770.011
regulation of homeostatic processGO:00328441210.011
divalent inorganic cation homeostasisGO:00725071360.011
response to organic cyclic compoundGO:00140702040.011
negative regulation of protein processingGO:00109551420.011
chemotaxisGO:00069351570.011
calcium ion transportGO:00068161470.011
non canonical wnt signaling pathway via mapk cascadeGO:003803040.011
alcohol metabolic processGO:00060661140.011
cellular response to cytokine stimulusGO:00713451810.011
negative regulation of mitotic cell cycleGO:00459301020.011
cellular response to extracellular stimulusGO:0031668720.011
reproductive processGO:00224141060.011
negative regulation of cellular component organizationGO:00511292350.011
mapk cascadeGO:00001652880.011
fatty acid metabolic processGO:00066311150.011
cell part morphogenesisGO:00329901370.011
regulation of intracellular protein transportGO:00331571230.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
endomembrane system organizationGO:00102561960.011
stem cell divisionGO:001714520.011
stress activated mapk cascadeGO:0051403930.011
cation transportGO:00068123310.011
peptidyl tyrosine modificationGO:00182121700.011
cell matrix adhesionGO:0007160850.011
regulation of intracellular transportGO:00323861950.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
negative regulation of transferase activityGO:00513481240.011
regulation of behaviorGO:0050795820.011
regulation of cell matrix adhesionGO:0001952420.011
positive regulation of rho gtpase activityGO:0032321560.011
cyclic nucleotide metabolic processGO:0009187820.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
defense response to bacteriumGO:0042742630.011
regulation of rho gtpase activityGO:0032319660.011
response to hypoxiaGO:0001666960.011
cell cycle g1 s phase transitionGO:0044843800.011
ribose phosphate biosynthetic processGO:0046390820.011
fear responseGO:004259600.011
regulation of cell developmentGO:00602841610.011
response to nutrient levelsGO:0031667810.011
syncytium formation by plasma membrane fusionGO:000076820.011
regulation of mapk cascadeGO:00434082620.011
response to extracellular stimulusGO:0009991850.011
response to tumor necrosis factorGO:0034612760.011
regulation of metal ion transportGO:00109591200.011
negative regulation of apoptotic processGO:00430663160.011
cellular calcium ion homeostasisGO:00068741170.011
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.011
histone h4 acetylationGO:0043967470.010
generation of neuronsGO:00486991520.010
jnk cascadeGO:0007254800.010
phospholipid metabolic processGO:0006644990.010
regulation of chemotaxisGO:0050920740.010
cation homeostasisGO:00550801890.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
negative regulation of cellular amine metabolic processGO:003323930.010
tripartite regional subdivisionGO:000735120.010
cellular response to potassium ionGO:003586550.010
negative regulation of protein ubiquitinationGO:0031397350.010
growthGO:00400072020.010
Fly
dephosphorylationGO:00163112090.010
muscle contractionGO:0006936730.010
negative regulation of phosphorylationGO:00423261740.010
ribonucleotide biosynthetic processGO:0009260810.010
glucose homeostasisGO:0042593310.010
microtubule cytoskeleton organizationGO:00002261760.010
maintenance of location in cellGO:0051651620.010
carbohydrate metabolic processGO:00059752070.010
receptor metabolic processGO:0043112810.010
mammary gland morphogenesisGO:006044320.010
positive regulation of protein transportGO:00512221350.010
purine ribonucleotide biosynthetic processGO:0009152790.010
associative learningGO:000830610.010
peripheral nervous system developmentGO:000742220.010

PIP4K2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.041
muscular diseaseDOID:00800001140.041
muscle tissue diseaseDOID:661130.025
muscular dystrophyDOID:9884510.025
myopathyDOID:4231040.025
central nervous system diseaseDOID:3311860.022
nervous system diseaseDOID:8634310.022
disease of metabolismDOID:00146672950.017
urinary system diseaseDOID:18400.013
inherited metabolic disorderDOID:6552420.013
disease of cellular proliferationDOID:145661740.012
immune system diseaseDOID:29141550.012
hematopoietic system diseaseDOID:741000.012
brain diseaseDOID:936730.011
sensory system diseaseDOID:00501552030.011
cancerDOID:1621670.011
organ system cancerDOID:00506861640.011
neurodegenerative diseaseDOID:12891020.010
disease of mental healthDOID:150700.010