Homo sapiens

167 known processes

PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

(Aliases: MGC130000,MGC130001,PAKalpha)

PAK1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rho protein signal transductionGO:0007266261.000
gtp metabolic processGO:00460392391.000
positive regulation of rho gtpase activityGO:0032321561.000
positive regulation of rac gtpase activityGO:0032855310.999
regulation of intracellular estrogen receptor signaling pathwayGO:0033146130.996
gtp catabolic processGO:00061842370.996
nucleoside catabolic processGO:00091644080.995
ribonucleoside triphosphate catabolic processGO:00092033910.994
purine ribonucleoside catabolic processGO:00461303980.994
small gtpase mediated signal transductionGO:0007264780.994
positive regulation of nucleotide catabolic processGO:00308131850.992
regulation of stress fiber assemblyGO:0051492320.992
ribonucleoside catabolic processGO:00424544060.990
positive regulation of gtpase activityGO:00435471660.990
regulation of nucleoside metabolic processGO:00091182090.990
guanosine containing compound metabolic processGO:19010682440.989
nucleoside triphosphate metabolic processGO:00091414220.989
positive regulation of gtp catabolic processGO:00331261660.989
ribonucleotide catabolic processGO:00092614050.987
purine nucleoside triphosphate catabolic processGO:00091463920.986
positive regulation of ras gtpase activityGO:00323201170.986
organophosphate catabolic processGO:00464344300.985
positive regulation of fibroblast migrationGO:001076330.985
regulation of cytoskeleton organizationGO:00514931770.983
ribonucleoside triphosphate metabolic processGO:00091994120.981
positive regulation of nucleotide metabolic processGO:00459812300.980
regulation of rho gtpase activityGO:0032319660.979
intracellular estrogen receptor signaling pathwayGO:0030520230.978
guanosine containing compound catabolic processGO:19010692390.974
nucleoside triphosphate catabolic processGO:00091433940.971
nucleotide catabolic processGO:00091664080.969
purine nucleoside catabolic processGO:00061523980.962
positive regulation of actin filament bundle assemblyGO:0032233250.959
purine ribonucleoside metabolic processGO:00461284370.957
glycosyl compound catabolic processGO:19016584130.954
actin cytoskeleton organizationGO:00300362070.951
purine nucleoside triphosphate metabolic processGO:00091444120.949
purine containing compound catabolic processGO:00725234110.948
purine ribonucleoside triphosphate catabolic processGO:00092073910.938
regulation of actin filament polymerizationGO:0030833500.932
Human
regulation of rho protein signal transductionGO:0035023790.931
positive regulation of purine nucleotide metabolic processGO:19005442270.926
positive regulation of actin filament polymerizationGO:0030838380.919
positive regulation of cellular component biogenesisGO:00440891580.918
contact inhibitionGO:006024230.910
ras protein signal transductionGO:0007265730.903
purine ribonucleotide catabolic processGO:00091544040.891
purine ribonucleoside triphosphate metabolic processGO:00092054110.881
positive regulation of purine nucleotide catabolic processGO:00331231850.880
nucleoside phosphate catabolic processGO:19012924120.876
positive regulation of protein polymerizationGO:0032273450.872
cdc42 protein signal transductionGO:003248840.866
regulation of protein kinase activityGO:00458592890.864
regulation of transferase activityGO:00513383550.863
regulation of actin filament bundle assemblyGO:0032231360.849
fibroblast migrationGO:001076170.848
regulation of gtpase activityGO:00430871800.836
regulation of actin cytoskeleton organizationGO:00329561160.825
cell adhesionGO:00071553250.817
regulation of small gtpase mediated signal transductionGO:00510561560.814
regulation of cell adhesionGO:00301551660.805
intracellular receptor signaling pathwayGO:00305221040.799
regulation of fibroblast migrationGO:001076270.796
negative regulation of catalytic activityGO:00430863350.781
Human
positive regulation of cytoskeleton organizationGO:0051495830.735
regulation of protein serine threonine kinase activityGO:00719001790.730
regulation of purine nucleotide catabolic processGO:00331212050.724
purine nucleotide catabolic processGO:00061954050.715
lamellipodium organizationGO:0097581300.706
positive regulation of protein complex assemblyGO:0031334860.701
regulation of cellular component biogenesisGO:00440872810.679
positive regulation of organelle organizationGO:00106381950.662
cellular component morphogenesisGO:00329893140.643
Rat
actin filament based processGO:00300292240.639
positive regulation of catabolic processGO:00098963100.631
cell morphogenesisGO:00009022960.623
Rat
positive regulation of nucleoside metabolic processGO:00459791860.612
regulation of gtp catabolic processGO:00331241800.604
regulation of nucleotide metabolic processGO:00061402690.595
regulation of protein polymerizationGO:0032271630.576
Human
regulation of ras gtpase activityGO:00323181280.574
establishment or maintenance of cell polarityGO:0007163310.554
Yeast
regulation of anatomical structure morphogenesisGO:00226032860.542
actin filament polymerizationGO:0030041450.541
Human
regulation of lamellipodium morphogenesisGO:200039240.541
astrocyte cell migrationGO:004361510.537
peptidyl serine phosphorylationGO:00181051010.527
cell projection organizationGO:00300302520.517
Mouse Rat
negative regulation of protein metabolic processGO:00512483910.510
Human
endomembrane system organizationGO:00102561960.510
regulation of peptidyl serine phosphorylationGO:0033135500.502
negative regulation of phosphate metabolic processGO:00459362670.500
regulation of cell cell adhesion mediated by cadherinGO:200004740.498
regulation of actin filament based processGO:00329701410.472
apoptotic signaling pathwayGO:00971902680.438
Human
tube developmentGO:00352951250.431
biological adhesionGO:00226103310.429
stress fiber assemblyGO:0043149400.425
regulation of cell projection organizationGO:00313441070.418
positive regulation of cellular component organizationGO:00511303760.408
regulation of kinase activityGO:00435493140.407
generation of neuronsGO:00486991520.401
Mouse Rat
negative regulation of hydrolase activityGO:00513461820.394
Human
regulation of cellular component sizeGO:0032535820.394
Human
dendritic spine morphogenesisGO:006099730.393
positive regulation of map kinase activityGO:0043406800.372
regulation of ras protein signal transductionGO:00465781550.369
actin filament organizationGO:00070151280.364
post embryonic developmentGO:000979120.359
Worm
organelle inheritanceGO:004830820.356
Yeast
regulation of nucleotide catabolic processGO:00308112050.338
amine metabolic processGO:0009308440.334
negative regulation of cellular protein metabolic processGO:00322693530.326
Human
positive regulation of apoptotic processGO:00430652460.325
Human Yeast
vacuole organizationGO:0007033440.325
Yeast
activation of protein kinase activityGO:0032147900.323
Human Yeast
cellular protein complex assemblyGO:00436231880.314
Human
negative regulation of cytoskeleton organizationGO:0051494450.304
regulation of purine nucleotide metabolic processGO:19005422640.296
regulation of anatomical structure sizeGO:00900661010.292
Human
positive regulation of lamellipodium organizationGO:1902745120.286
regulation of mitosisGO:0007088630.281
Yeast
cell morphogenesis involved in differentiationGO:00009041440.275
negative regulation of apoptotic processGO:00430663160.272
Human
negative regulation of protein modification processGO:00314002000.269
positive regulation of programmed cell deathGO:00430682490.267
Human Yeast
sterol transmembrane transportGO:003538240.265
Yeast
regulation of cellular ketone metabolic processGO:0010565500.263
regulation of protein complex assemblyGO:00432541470.258
Human
regulation of cell shapeGO:0008360480.250
regulation of cellular amino acid metabolic processGO:000652160.250
intracellular steroid hormone receptor signaling pathwayGO:0030518610.246
ubiquitin dependent protein catabolic processGO:00065112060.246
cellular macromolecular complex assemblyGO:00346223240.245
Human Yeast
positive regulation of stress fiber assemblyGO:0051496220.237
positive regulation of cell motilityGO:20001471770.236
negative regulation of protein maturationGO:19033181420.236
Human
positive regulation of cell deathGO:00109422630.235
Human Yeast
positive regulation of protein phosphorylationGO:00019343130.233
muscle structure developmentGO:0061061980.233
negative regulation of cell deathGO:00605483450.228
Human
regulation of peroxidase activityGO:200046820.225
protein catabolic processGO:00301633250.223
determination of adult lifespanGO:000834020.223
cell projection morphogenesisGO:00488581290.221
Rat
regulation of stress activated mapk cascadeGO:0032872840.221
response to organic cyclic compoundGO:00140702040.219
establishment or maintenance of cytoskeleton polarityGO:003095230.214
negative regulation of phosphorylationGO:00423261740.213
spermatid differentiationGO:004851540.212
single organism cellular localizationGO:19025803320.212
Yeast Mouse
positive regulation of protein kinase activityGO:00458601900.210
regulation of apoptotic signaling pathwayGO:20012331750.208
Human
eye photoreceptor cell differentiationGO:000175420.206
positive regulation of hydrolase activityGO:00513453310.199
actin filament bundle organizationGO:0061572540.198
regulation of stress activated protein kinase signaling cascadeGO:0070302850.196
regulation of cell cycleGO:00517263930.192
Yeast
sterol transportGO:0015918390.183
Yeast
negative regulation of catabolic processGO:00098951040.182
positive regulation of kinase activityGO:00336742040.182
response to steroid hormoneGO:0048545800.181
actin polymerization or depolymerizationGO:0008154560.180
Human
modification dependent macromolecule catabolic processGO:00436322120.180
regulation of protein ubiquitinationGO:0031396950.179
positive regulation of jnk cascadeGO:0046330520.177
synaptic vesicle endocytosisGO:004848820.176
regulation of execution phase of apoptosisGO:1900117110.173
Human
regulation of neurotransmitter secretionGO:004692830.173
mitotic cell cycleGO:00002783260.170
Yeast
single organism nuclear importGO:19025931040.170
Yeast
single organism cell adhesionGO:00986021790.167
regulation of cellular amine metabolic processGO:0033238110.166
cell developmentGO:00484683280.166
Mouse Rat
nuclear importGO:00511701060.160
Yeast
response to hormoneGO:00097251750.157
Rat
cellular response to abiotic stimulusGO:00712141170.156
Yeast
negative regulation of apoptotic signaling pathwayGO:2001234970.153
negative regulation of programmed cell deathGO:00430693210.152
Human
positive regulation of transferase activityGO:00513472270.151
cellular response to heatGO:0034605140.151
Yeast
neurotransmitter secretionGO:000726940.149
exit from mitosisGO:0010458100.148
Yeast
vesicle organizationGO:0016050620.147
negative regulation of endopeptidase activityGO:0010951840.144
Human
positive regulation of cellular catabolic processGO:00313312840.144
cellular amine metabolic processGO:0044106410.143
anterior posterior axis specification embryoGO:000859520.139
positive regulation of apoptotic signaling pathwayGO:2001235700.138
Human
regulation of protein targetingGO:1903533910.136
Yeast
regulation of jun kinase activityGO:0043506270.136
positive regulation of cell adhesionGO:0045785840.135
positive regulation of cell projection organizationGO:0031346640.135
stress activated mapk cascadeGO:0051403930.133
locomotory behaviorGO:000762610.132
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.131
Human
positive regulation of lamellipodium morphogenesisGO:200039420.131
positive regulation of protein transportGO:00512221350.130
Yeast
response to abiotic stimulusGO:00096283360.129
Yeast Rat
regulation of synaptic vesicle transportGO:190280330.127
cell divisionGO:00513011680.127
Yeast
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.126
Human
modification dependent protein catabolic processGO:00199412090.125
tripartite regional subdivisionGO:000735120.123
regulation of neuron deathGO:1901214560.122
tangential migration from the subventricular zone to the olfactory bulbGO:002202830.122
positive regulation of phosphorylationGO:00423273940.120
cell projection assemblyGO:00300311260.119
regulation of actin polymerization or depolymerizationGO:0008064560.119
Human
organic hydroxy compound transportGO:0015850630.116
Yeast
regulation of synaptic vesicle endocytosisGO:190024210.115
activation of mapkk activityGO:0000186180.111
Yeast
protein polymerizationGO:0051258710.109
Human
mitotic cell cycle phase transitionGO:00447721620.108
neuromuscular junction developmentGO:000752830.107
Mouse
regulation of cdc42 protein signal transductionGO:0032489140.107
positive regulation of peptidyl serine phosphorylationGO:0033138420.106
compound eye developmentGO:004874910.106
positive regulation of substrate adhesion dependent cell spreadingGO:1900026150.105
positive regulation of developmental processGO:00510943140.103
tube morphogenesisGO:0035239950.099
substrate adhesion dependent cell spreadingGO:0034446410.098
microtubule cytoskeleton organizationGO:00002261760.096
filopodium assemblyGO:0046847180.093
cell growthGO:00160491600.093
Yeast
organelle fissionGO:00482851490.093
Yeast
epidermal cell differentiationGO:0009913450.092
keratinocyte differentiationGO:0030216360.089
positive regulation of jun kinase activityGO:0043507230.086
negative regulation of transferase activityGO:00513481240.085
regulation of protein transportGO:00512232130.080
Yeast
anterior posterior axis specificationGO:000994820.080
golgi organizationGO:0007030380.079
morphogenesis of a branching structureGO:0001763210.079
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.078
regulation of endopeptidase activityGO:00525481700.078
Human
regulation of cell morphogenesisGO:00226041530.078
transmembrane transportGO:00550853990.077
Yeast
branching morphogenesis of an epithelial tubeGO:0048754190.076
protein maturationGO:00516042330.076
Human
central nervous system developmentGO:00074171230.075
regulation of cell substrate adhesionGO:0010810680.072
cell competition in a multicellular organismGO:003521210.072
cellular amino acid metabolic processGO:00065201160.072
activation of mapk activityGO:0000187450.068
Human
establishment of protein localization to organelleGO:00725941720.068
Yeast
negative regulation of protein kinase activityGO:0006469980.067
protein targeting to nucleusGO:00447441040.066
Yeast
regionalizationGO:0003002290.066
oocyte developmentGO:004859910.066
cell cell adhesion mediated by cadherinGO:004433140.066
negative regulation of protein processingGO:00109551420.066
Human
cellular response to ammonium ionGO:007124240.066
peptidyl serine modificationGO:00182091060.066
regulation of synaptic vesicle exocytosisGO:200030020.065
blastocyst developmentGO:000182430.065
cell migration involved in gastrulationGO:004207410.065
negative regulation of phosphorus metabolic processGO:00105632670.065
positive regulation of cell substrate adhesionGO:0010811370.064
regulation of map kinase activityGO:00434051080.062
segmentationGO:003528240.061
nervous system developmentGO:00073992930.061
Mouse Rat
cellular response to metal ionGO:0071248430.061
regulation of mitotic cell cycleGO:00073461890.061
Yeast
negative regulation of protein phosphorylationGO:00019331400.060
g protein coupled receptor signaling pathwayGO:00071862070.059
Yeast
regulation of dna metabolic processGO:00510521530.059
cellular ketone metabolic processGO:0042180800.059
negative regulation of neuron apoptotic processGO:0043524230.058
chordate embryonic developmentGO:0043009340.058
positive regulation of mapk cascadeGO:00434101900.057
regulation of protein processingGO:00706131500.057
Human
intracellular protein transportGO:00068862700.057
Yeast
regulation of cell motilityGO:20001452990.056
extrinsic apoptotic signaling pathwayGO:00971911190.056
Human
nucleocytoplasmic transportGO:00069131760.055
Yeast
dna replicationGO:00062601160.054
negative regulation of peptidase activityGO:0010466910.054
Human
actin filament bundle assemblyGO:0051017540.054
ribonucleoprotein complex biogenesisGO:00226131160.054
Yeast
stress activated protein kinase signaling cascadeGO:0031098940.053
sex determinationGO:000753030.053
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.052
digestive tract developmentGO:0048565750.052
positive regulation of metalloenzyme activityGO:004855420.051
neuron projection morphogenesisGO:0048812500.051
Rat
neural tube formationGO:000184130.050
establishment or maintenance of neuroblast polarityGO:004519610.049
response to estrogenGO:0043627470.049
regulation of actin filament lengthGO:0030832560.049
Human
dephosphorylationGO:00163112090.048
regulation of neuron apoptotic processGO:0043523350.048
negative regulation of posttranscriptional gene silencingGO:006014930.048
circulatory system developmentGO:00723592620.047
regulation of actin nucleationGO:0051125100.047
regulation of cell cycle processGO:00105642660.047
Yeast
response to metal ionGO:0010038840.047
proteasomal protein catabolic processGO:00104981760.047
microtubule based processGO:00070172100.047
cell type specific apoptotic processGO:00972851250.046
response to peptidoglycanGO:003249430.046
mitochondrion distributionGO:004831130.046
embryonic epithelial tube formationGO:000183840.046
single organism reproductive processGO:0044702980.046
Worm
cellular macromolecule catabolic processGO:00442653800.045
system processGO:00030083490.045
negative regulation of proteolysisGO:00458611320.045
Human
protein import into nucleusGO:00066061040.045
Yeast
protein modification by small protein conjugationGO:00324463420.044
hindbrain developmentGO:003090230.044
response to oxygen containing compoundGO:19017003690.044
Rat
regulation of jnk cascadeGO:0046328730.044
negative regulation of cellular component organizationGO:00511292350.044
specification of axis polarityGO:006500110.043
regulation of protein maturationGO:19033171500.043
Human
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.043
immune system developmentGO:00025201950.043
endocytosisGO:00068971590.043
organ morphogenesisGO:00098871470.042
Worm
neuron apoptotic processGO:0051402390.042
positive regulation of cellular amine metabolic processGO:003324070.042
thrombin receptor signaling pathwayGO:007049350.041
protein importGO:00170381300.041
Yeast
mapk cascadeGO:00001652880.040
maintenance of cell polarityGO:003001120.040
growthGO:00400072020.040
Yeast
regulation of cell morphogenesis involved in differentiationGO:0010769830.040
positive regulation of neuron apoptotic processGO:004352580.040
regulation of cell projection assemblyGO:0060491470.040
regulation of cell divisionGO:00513021160.039
Yeast
regulation of autophagyGO:0010506520.039
forebrain neuron developmentGO:002188420.038
ribonucleoprotein complex subunit organizationGO:0071826810.037
Yeast
regulation of dendrite morphogenesisGO:0048814110.037
establishment of organelle localizationGO:0051656590.036
glial cell migrationGO:000834740.036
negative regulation of intracellular steroid hormone receptor signaling pathwayGO:0033144180.036
establishment of cell polarityGO:0030010220.036
Yeast
protein autophosphorylationGO:00467771230.036
positive regulation of mitochondrial calcium ion concentrationGO:005156180.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
limbic system developmentGO:002176130.035
regulation of cell developmentGO:00602841610.035
protein targetingGO:00066051870.035
Yeast
cell matrix adhesionGO:0007160850.035
regulation of substrate adhesion dependent cell spreadingGO:1900024190.034
negative regulation of dephosphorylationGO:0035305630.034
lamellipodium assemblyGO:0030032260.033
single organism membrane organizationGO:00448022680.033
Mouse
negative regulation of cellular amine metabolic processGO:003323930.033
regulation of cell differentiationGO:00455953930.033
positive regulation of transportGO:00510503360.033
Yeast
positive regulation of protein localization to nucleusGO:1900182480.032
Yeast
regulation of cdc42 gtpase activityGO:0043088100.032
protein ubiquitinationGO:00165673140.032
response to nitrogen compoundGO:19016981840.032
Rat
protein localization to organelleGO:00333652800.032
Yeast
regulation of arp2 3 complex mediated actin nucleationGO:003431560.031
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.031
exocytosisGO:0006887710.031
negative regulation of organelle organizationGO:00106391260.031
cytokinesisGO:0000910960.031
Yeast
establishment of planar polarityGO:000173630.030
negative regulation of nucleotide catabolic processGO:0030812160.030
positive regulation of actin nucleationGO:005112760.030
regulation of secretionGO:00510461940.030
negative regulation of protein ubiquitinationGO:0031397350.030
cloaca developmentGO:003584410.030
negative regulation of rho gtpase activityGO:003425940.030
nuclear divisionGO:00002801280.029
Yeast
photoreceptor cell differentiationGO:004653020.029
inner ear morphogenesisGO:004247240.029
olfactory bulb interneuron differentiationGO:002188920.028
synaptic vesicle recyclingGO:003646530.028
regulation of mapk cascadeGO:00434082620.028
synaptic transmissionGO:0007268610.028
vesicle mediated transportGO:00161923710.028
protein localization to nucleusGO:00345041360.028
Yeast
cellular protein catabolic processGO:00442572610.028
response to heatGO:0009408210.027
Yeast
negative regulation of actin nucleationGO:005112630.026
regulation of proteolysisGO:00301622930.026
Human
multicellular organismal agingGO:001025930.026
response to temperature stimulusGO:0009266220.026
Yeast
regulation of cell growthGO:00015581350.026
anatomical structure formation involved in morphogenesisGO:00486462840.026
somatic muscle developmentGO:000752510.026
regulation of cellular response to stressGO:00801352440.026
neuron deathGO:0070997650.026
signal transduction by phosphorylationGO:00230142970.026
cellular response to inorganic substanceGO:0071241450.026
morphogenesis of a polarized epitheliumGO:000173830.025
negative regulation of dna metabolic processGO:0051053570.025
cerebral cortex cell migrationGO:002179530.025
regulation of protein tyrosine kinase activityGO:0061097360.025
Human
negative regulation of cellular catabolic processGO:0031330830.025
hemidesmosome assemblyGO:003158150.025
Worm
regulation of growth rateGO:004000910.025
collateral sproutingGO:004866820.025
regulation of neuroblast proliferationGO:190269230.025
macroautophagyGO:0016236390.024
regulation of exit from mitosisGO:000709660.024
Yeast
response to activityGO:001482300.024
morphogenesis of embryonic epitheliumGO:001633140.024
epidermis developmentGO:0008544590.024
negative regulation of neuron deathGO:1901215320.024
gonad developmentGO:0008406340.024
Worm
organelle localizationGO:0051640840.024
regulation of carbohydrate metabolic processGO:0006109540.024
rac protein signal transductionGO:0016601120.024
hippocampus developmentGO:002176610.023
lipid metabolic processGO:00066293810.023
mitotic cell cycle processGO:19030472860.023
Yeast
cell part morphogenesisGO:00329901370.023
Rat
visual behaviorGO:000763220.023
agingGO:0007568660.023
neuron fate commitmentGO:004866320.023
regulation of developmental growthGO:0048638300.023
rna processingGO:00063962550.023
skin developmentGO:0043588760.023
establishment of tissue polarityGO:000716430.022
regulation of protein autoubiquitinationGO:190249830.022
arp2 3 complex mediated actin nucleationGO:0034314170.022
cell fate commitmentGO:0045165270.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
pattern specification processGO:0007389430.022
t cell tolerance inductionGO:000251740.022
dopamine receptor signaling pathwayGO:0007212100.022
response to osmotic stressGO:0006970170.022
Yeast
oocyte differentiationGO:000999420.021
vasculature developmentGO:00019441810.021
response to fungusGO:000962040.021
cellular response to calcium ionGO:0071277190.021
mitochondrial calcium ion homeostasisGO:0051560110.021
cerebellum developmentGO:002154920.021
cell fate commitment involved in pattern specificationGO:006058110.021
actomyosin structure organizationGO:0031032590.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.021
primary neural tube formationGO:001402030.020
leukocyte proliferationGO:0070661740.020
establishment of protein localization to mitochondrionGO:0072655220.020
embryonic morphogenesisGO:0048598850.020
Worm
negative regulation of execution phase of apoptosisGO:190011860.020
Human
embryonic organ developmentGO:0048568360.020
regulation of cell cell adhesionGO:0022407570.020
positive regulation of cell migrationGO:00303351720.020
myoblast fusionGO:000752010.020
adherens junction organizationGO:0034332360.020
secretory granule organizationGO:003336320.020
peptidyl threonine phosphorylationGO:0018107410.020
negative regulation of blood circulationGO:190352340.020
positive regulation of cell developmentGO:0010720920.019
mitotic nuclear divisionGO:00070671190.019
Yeast
membrane buddingGO:0006900280.019
adherens junction assemblyGO:0034333340.019
positive regulation of synapse structural plasticityGO:005183520.019
semaphorin plexin signaling pathwayGO:007152640.019
developmental cell growthGO:0048588180.019
positive regulation of stress activated mapk cascadeGO:0032874600.019
sensory organ developmentGO:0007423520.019
response to lipidGO:00339932060.019
asymmetric stem cell divisionGO:009872210.019
cell substrate junction assemblyGO:0007044350.019
Worm
embryo developmentGO:00097901230.018
Worm
synaptic vesicle exocytosisGO:001607930.018
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314770.018
metencephalon developmentGO:002203720.018
negative regulation of kinase activityGO:00336731060.018
regulation of locomotionGO:00400123290.018
cellular response to endogenous stimulusGO:00714953360.018
Rat
ectodermal placode developmentGO:007169610.018
positive regulation of growthGO:0045927580.018
cell cycle phase transitionGO:00447701730.018
negative regulation of map kinase activityGO:0043407270.018
positive regulation of lamellipodium assemblyGO:001059290.018
regulation of growthGO:00400081650.018
gastrulationGO:0007369510.018
developmental growthGO:0048589480.017
glycerolipid metabolic processGO:00464861070.017
response to epidermal growth factorGO:0070849140.017

PAK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:150700.096
Human
intellectual disabilityDOID:1059130.096
Human
developmental disorder of mental healthDOID:0060037290.096
Human
specific developmental disorderDOID:0060038190.096
Human
non syndromic intellectual disabilityDOID:005088990.085
Human
non specific x linked mental retardationDOID:005077670.085
Human
urinary system diseaseDOID:18400.033
musculoskeletal system diseaseDOID:172230.025
muscular diseaseDOID:00800001140.025
kidney diseaseDOID:557360.022
disease of metabolismDOID:00146672950.020
inherited metabolic disorderDOID:6552420.020
nephrotic syndromeDOID:1184100.018
nephrosisDOID:2527100.018