Homo sapiens

14 known processes

HEXA

hexosaminidase A (alpha polypeptide)

(Aliases: TSD,MGC99608)

HEXA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glial cell migrationGO:000834740.218
histone h3 k79 methylationGO:003472920.099
cellular macromolecule catabolic processGO:00442653800.095
proteolysis involved in cellular protein catabolic processGO:00516032440.092
cellular amine metabolic processGO:0044106410.090
lipid metabolic processGO:00066293810.086
Mouse
single organism carbohydrate metabolic processGO:00447231930.082
lipid catabolic processGO:0016042840.080
Mouse
ubiquitin dependent protein catabolic processGO:00065112060.074
regulation of cellular amino acid metabolic processGO:000652160.070
regulation of cellular amine metabolic processGO:0033238110.068
histone deubiquitinationGO:0016578160.064
cellular lipid metabolic processGO:00442553030.063
Mouse
cellular protein catabolic processGO:00442572610.062
modification dependent protein catabolic processGO:00199412090.061
protein modification by small protein conjugationGO:00324463420.061
determination of adult lifespanGO:000834020.060
positive regulation of cellular amine metabolic processGO:003324070.059
amine metabolic processGO:0009308440.059
protein catabolic processGO:00301633250.058
cellular amino acid metabolic processGO:00065201160.056
post embryonic developmentGO:000979120.054
modification dependent macromolecule catabolic processGO:00436322120.052
regulation of cell cycleGO:00517263930.050
carbohydrate metabolic processGO:00059752070.050
chemotaxisGO:00069351570.049
system processGO:00030083490.047
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.046
macromolecule methylationGO:0043414970.046
cellular lipid catabolic processGO:0044242650.044
Mouse
cellular ketone metabolic processGO:0042180800.043
protein deubiquitinationGO:0016579790.043
rna processingGO:00063962550.042
maintenance of locationGO:00512351120.042
Mouse
cellular component morphogenesisGO:00329893140.041
Mouse
rna splicingGO:00083801310.041
protein modification by small protein removalGO:0070646920.041
nervous system developmentGO:00073992930.040
Mouse
histone methylationGO:0016571600.040
multicellular organismal agingGO:001025930.039
cell morphogenesisGO:00009022960.038
Mouse
oogenesisGO:004847720.037
taxisGO:00423301570.037
covalent chromatin modificationGO:00165692540.036
protein alkylationGO:0008213740.036
regulation of mitotic cell cycleGO:00073461890.035
cell projection organizationGO:00300302520.035
sphingolipid metabolic processGO:0006665380.035
Mouse
neurological system processGO:00508771630.035
Mouse
segmentationGO:003528240.034
response to oxygen containing compoundGO:19017003690.034
cellular response to endogenous stimulusGO:00714953360.034
histone h3 k4 methylationGO:0051568270.033
methylationGO:00322591060.033
chromatin modificationGO:00165682980.033
carbohydrate derivative biosynthetic processGO:19011372070.033
histone h3 acetylationGO:0043966450.033
positive regulation of immune system processGO:00026842830.032
defense responseGO:00069523150.032
cytoplasmic transportGO:00164823790.031
liposaccharide metabolic processGO:1903509270.031
Mouse
vesicle mediated transportGO:00161923710.031
membrane lipid metabolic processGO:0006643530.031
Mouse
mitotic cell cycleGO:00002783260.031
lipid localizationGO:00108761060.031
Mouse
histone modificationGO:00165702510.030
chromatin organizationGO:00063253510.030
immune responseGO:00069553070.030
glycoprotein metabolic processGO:00091001100.029
posttranscriptional regulation of gene expressionGO:00106082130.029
histone acetylationGO:0016573930.029
regenerationGO:003109940.029
protein methylationGO:0006479740.029
locomotory behaviorGO:000762610.029
Mouse
female gamete generationGO:000729220.029
epithelium developmentGO:00604292270.028
positive regulation of phosphorylationGO:00423273940.028
protein acylationGO:00435431380.028
secretionGO:00469032540.028
transmembrane transportGO:00550853990.028
negative regulation of catalytic activityGO:00430863350.028
regulation of secretionGO:00510461940.027
regulation of cellular response to stressGO:00801352440.027
purine ribonucleoside metabolic processGO:00461284370.027
histone ubiquitinationGO:0016574310.027
positive regulation of transportGO:00510503360.027
ganglioside metabolic processGO:000157370.027
Mouse
ribonucleoside catabolic processGO:00424544060.026
cell developmentGO:00484683280.026
Mouse
histone lysine methylationGO:0034968500.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
lipid biosynthetic processGO:00086101770.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
response to abiotic stimulusGO:00096283360.026
organophosphate catabolic processGO:00464344300.025
generation of neuronsGO:00486991520.025
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.025
peptidyl lysine modificationGO:00182051440.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
nucleoside triphosphate metabolic processGO:00091414220.025
negative regulation of protein metabolic processGO:00512483910.024
neurogenesisGO:00220081690.024
Mouse
small molecule biosynthetic processGO:00442831570.024
cell morphogenesis involved in differentiationGO:00009041440.023
Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.023
negative regulation of multicellular organismal processGO:00512413170.023
regulation of purine nucleotide metabolic processGO:19005422640.023
regulation of cellular ketone metabolic processGO:0010565500.023
neuromuscular junction developmentGO:000752830.023
rho protein signal transductionGO:0007266260.023
neuron differentiationGO:00301821380.023
Mouse
negative regulation of phosphate metabolic processGO:00459362670.023
nucleoside phosphate catabolic processGO:19012924120.023
internal peptidyl lysine acetylationGO:0018393970.023
dephosphorylationGO:00163112090.023
positive regulation of immune responseGO:00507781590.023
signal transduction by phosphorylationGO:00230142970.023
glycosyl compound catabolic processGO:19016584130.022
regulation of cellular component movementGO:00512703340.022
single organism membrane organizationGO:00448022680.022
nucleotide catabolic processGO:00091664080.022
protein glycosylationGO:0006486620.022
cytokine productionGO:00018162470.022
small gtpase mediated signal transductionGO:0007264780.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
neuron developmentGO:00486661130.022
Mouse
secretion by cellGO:00329402260.022
ribonucleotide catabolic processGO:00092614050.022
apoptotic signaling pathwayGO:00971902680.022
positive regulation of hydrolase activityGO:00513453310.021
regulation of intracellular transportGO:00323861950.021
vacuole organizationGO:0007033440.021
Mouse
internal protein amino acid acetylationGO:00064751010.021
actin filament based processGO:00300292240.021
protein acetylationGO:00064731160.021
purine nucleoside catabolic processGO:00061523980.021
organophosphate biosynthetic processGO:00904071630.021
hindbrain developmentGO:003090230.021
glycoprotein biosynthetic processGO:0009101910.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
peptidyl lysine acetylationGO:00183941010.021
cellular response to oxygen containing compoundGO:19017012760.021
ras protein signal transductionGO:0007265730.021
ion transmembrane transportGO:00342203380.021
matingGO:000761810.020
metencephalon developmentGO:002203720.020
organonitrogen compound biosynthetic processGO:19015662000.020
membrane organizationGO:00610242920.020
macromolecule glycosylationGO:0043413630.020
nucleoside catabolic processGO:00091644080.020
negative regulation of phosphorus metabolic processGO:00105632670.020
histone h4 acetylationGO:0043967470.020
purine containing compound catabolic processGO:00725234110.020
regulation of mapk cascadeGO:00434082620.020
negative regulation of cell proliferationGO:00082852280.020
mapk cascadeGO:00001652880.019
regulation of cellular component biogenesisGO:00440872810.019
protein localization to organelleGO:00333652800.019
innate immune responseGO:00450871780.019
regulation of transferase activityGO:00513383550.019
growthGO:00400072020.019
positive regulation of cell proliferationGO:00082843010.019
protein maturationGO:00516042330.019
negative regulation of cellular amine metabolic processGO:003323930.019
cell activationGO:00017752130.019
cell part morphogenesisGO:00329901370.019
negative regulation of intracellular signal transductionGO:19025321830.019
purine nucleotide catabolic processGO:00061954050.019
regulation of cell cycle processGO:00105642660.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
regulation of secretion by cellGO:19035301770.018
reactive oxygen species biosynthetic processGO:190340940.018
positive regulation of organelle organizationGO:00106381950.018
regulation of protein transportGO:00512232130.018
regulation of vesicle mediated transportGO:00606271300.018
cellular amide metabolic processGO:0043603690.018
cell projection morphogenesisGO:00488581290.018
regulation of cell motilityGO:20001452990.018
regulation of anatomical structure morphogenesisGO:00226032860.018
rna interferenceGO:001624640.018
regulation of protein localizationGO:00328802960.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of nucleotide metabolic processGO:00061402690.018
tissue regenerationGO:004224630.018
reactive oxygen species metabolic processGO:0072593750.018
cellular ion homeostasisGO:00068731680.018
ion homeostasisGO:00508012300.018
nucleoside triphosphate catabolic processGO:00091433940.018
cellular protein complex assemblyGO:00436231880.018
gtp metabolic processGO:00460392390.018
anion transportGO:00068201610.018
endocytosisGO:00068971590.018
oxidation reduction processGO:00551143960.017
neuron projection developmentGO:00311751060.017
neural tube formationGO:000184130.017
purine ribonucleoside catabolic processGO:00461303980.017
positive regulation of catabolic processGO:00098963100.017
regulation of cell migrationGO:00303342890.017
sulfur compound metabolic processGO:00067901010.017
positive regulation of cell deathGO:00109422630.017
cellular response to dna damage stimulusGO:00069743790.017
purine ribonucleotide catabolic processGO:00091544040.017
regulation of protein kinase activityGO:00458592890.017
negative regulation of protein modification processGO:00314002000.017
proteasomal protein catabolic processGO:00104981760.017
metal ion transportGO:00300012720.017
carbohydrate catabolic processGO:0016052360.017
regulation of proteolysisGO:00301622930.017
cellular macromolecular complex assemblyGO:00346223240.017
regulation of kinase activityGO:00435493140.017
regulation of establishment of protein localizationGO:00702012420.017
cell adhesionGO:00071553250.016
single organism cellular localizationGO:19025803320.016
biological adhesionGO:00226103310.016
cation transmembrane transportGO:00986552380.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
regulation of peptidase activityGO:00525471800.016
memoryGO:000761330.016
glycolipid metabolic processGO:0006664270.016
Mouse
positive regulation of cellular component organizationGO:00511303760.016
regulation of response to external stimulusGO:00321012220.016
positive regulation of protein phosphorylationGO:00019343130.016
reactive nitrogen species metabolic processGO:200105730.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
mitochondrion organizationGO:00070051560.016
guanosine containing compound metabolic processGO:19010682440.016
microtubule based processGO:00070172100.016
negative regulation of cell deathGO:00605483450.016
response to nitrogen compoundGO:19016981840.016
response to lipidGO:00339932060.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
oocyte developmentGO:004859910.016
peptidyl tyrosine modificationGO:00182121700.016
regulation of cell activationGO:00508651250.016
adult locomotory behaviorGO:000834410.016
Mouse
regulation of immune responseGO:00507762010.016
regulation of protein stabilityGO:0031647870.016
peripheral nervous system developmentGO:000742220.016
leukocyte activationGO:00453211640.015
cation transportGO:00068123310.015
alcohol metabolic processGO:00060661140.015
neurotransmitter secretionGO:000726940.015
negative regulation of phosphorylationGO:00423261740.015
negative regulation of cellular component organizationGO:00511292350.015
response to bacteriumGO:00096171440.015
positive regulation of developmental processGO:00510943140.015
phospholipid metabolic processGO:0006644990.015
blastoderm segmentationGO:000735020.015
chemical homeostasisGO:00488783060.015
negative regulation of hydrolase activityGO:00513461820.015
response to hormoneGO:00097251750.015
guanosine containing compound catabolic processGO:19010692390.015
somitogenesisGO:000175620.015
spermatid developmentGO:000728640.015
positive regulation of mitotic cell cycleGO:0045931600.015
cellular response to nitrogen compoundGO:19016991440.015
morphogenesis of embryonic epitheliumGO:001633140.015
negative regulation of apoptotic processGO:00430663160.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of kinase activityGO:00336742040.014
tissue homeostasisGO:0001894630.014
regulation of protein complex assemblyGO:00432541470.014
regulation of leukocyte activationGO:00026941150.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
regulation of ion transportGO:00432691890.014
protein processingGO:00164852260.014
positive regulation of programmed cell deathGO:00430682490.014
response to external biotic stimulusGO:00432072610.014
response to woundingGO:00096111680.014
circulatory system developmentGO:00723592620.014
regulation of nucleotide catabolic processGO:00308112050.014
intracellular protein transportGO:00068862700.014
oocyte differentiationGO:000999420.014
positive regulation of apoptotic processGO:00430652460.014
cellular homeostasisGO:00197251960.014
epithelial cell proliferationGO:00506731280.014
syncytium formation by plasma membrane fusionGO:000076820.014
glycerolipid metabolic processGO:00464861070.014
cellular carbohydrate metabolic processGO:0044262840.014
positive regulation of transferase activityGO:00513472270.014
regulation of cell morphogenesisGO:00226041530.014
carboxylic acid biosynthetic processGO:0046394970.014
nitrogen compound transportGO:00717051910.014
regulation of immune effector processGO:0002697910.014
regulation of gtp catabolic processGO:00331241800.013
positive regulation of secretionGO:00510471160.013
cell growthGO:00160491600.013
negative regulation of developmental processGO:00510932470.013
organic acid biosynthetic processGO:0016053970.013
rhythmic behaviorGO:000762220.013
spermatid differentiationGO:004851540.013
regulation of nucleoside metabolic processGO:00091182090.013
cation homeostasisGO:00550801890.013
organic hydroxy compound metabolic processGO:19016151470.013
limbic system developmentGO:002176130.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
protein ubiquitinationGO:00165673140.013
monocarboxylic acid metabolic processGO:00327871850.013
epithelial cell differentiationGO:00308551410.013
positive regulation of nucleotide metabolic processGO:00459812300.013
response to fungusGO:000962040.013
cellular metal ion homeostasisGO:00068751460.013
single organism carbohydrate catabolic processGO:0044724330.013
sequestering of metal ionGO:0051238240.013
negative regulation of synaptic transmissionGO:005080520.013
peptide metabolic processGO:0006518510.013
anterior posterior axis specificationGO:000994820.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
Mouse
anatomical structure homeostasisGO:00602491000.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
immune effector processGO:00022521590.013
gtp catabolic processGO:00061842370.013
regulation of defense responseGO:00313471540.013
regulation of meiotic cell cycleGO:005144540.012
compound eye developmentGO:004874910.012
positive regulation of synaptic transmissionGO:005080640.012
response to growth factorGO:00708482050.012
positive regulation of nucleoside metabolic processGO:00459791860.012
positive regulation of cell activationGO:0050867810.012
regulation of cell adhesionGO:00301551660.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
positive regulation of cell differentiationGO:00455972110.012
positive regulation of cellular catabolic processGO:00313312840.012
negative regulation of transportGO:00510511760.012
positive regulation of protein kinase activityGO:00458601900.012
protein oligomerizationGO:00512591730.012
atp metabolic processGO:00460341760.012
activation of immune responseGO:00022531140.012
nerve developmentGO:002167540.012
regulation of cytokine productionGO:00018172320.012
monovalent inorganic cation transportGO:00156721280.012
cellular chemical homeostasisGO:00550821800.012
blastocyst developmentGO:000182430.012
positive regulation of gtp catabolic processGO:00331261660.012
sensory perception of painGO:001923340.012
inner ear morphogenesisGO:004247240.012
regulation of cytoskeleton organizationGO:00514931770.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
response to biotic stimulusGO:00096072760.012
actin cytoskeleton organizationGO:00300362070.012
response to other organismGO:00517072610.012
translationGO:00064121320.012
positive regulation of ras gtpase activityGO:00323201170.012
response to axon injuryGO:004867810.012
positive regulation of cellular component biogenesisGO:00440891580.012
regulation of protein catabolic processGO:00421761550.012
cell projection assemblyGO:00300311260.012
response to organic cyclic compoundGO:00140702040.012
associative learningGO:000830610.012
glycerophospholipid metabolic processGO:0006650840.012
nucleoside monophosphate metabolic processGO:00091231910.012
response to salt stressGO:000965130.012
tripartite regional subdivisionGO:000735120.012
photoreceptor cell differentiationGO:004653020.012
negative regulation of locomotionGO:00400131180.012
regulation of gtpase activityGO:00430871800.012
divalent inorganic cation homeostasisGO:00725071360.012
regulation of vasculature developmentGO:1901342970.012
regulation of ras gtpase activityGO:00323181280.012
metal ion homeostasisGO:00550651690.012
regulation of apoptotic signaling pathwayGO:20012331750.012
cellular response to hormone stimulusGO:00328701250.012
ceramide metabolic processGO:0006672250.012
Mouse
regulation of protein serine threonine kinase activityGO:00719001790.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
organic anion transportGO:00157111030.012
regulation of ras protein signal transductionGO:00465781550.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
cardiac muscle cell contractionGO:008600340.012
divalent inorganic cation transportGO:00725111580.012
peptidyl tyrosine phosphorylationGO:00181081700.011
negative regulation of transferase activityGO:00513481240.011
inorganic ion transmembrane transportGO:00986602310.011
endosomal transportGO:00161971290.011
small molecule catabolic processGO:0044282920.011
regulation of purine nucleotide catabolic processGO:00331212050.011
microtubule cytoskeleton organizationGO:00002261760.011
positive regulation of cytokine productionGO:00018191670.011
regulation of dephosphorylationGO:0035303960.011
cell morphogenesis involved in neuron differentiationGO:0048667440.011
Mouse
negative regulation of protein phosphorylationGO:00019331400.011
regulation of protein maturationGO:19033171500.011
cell cycle phase transitionGO:00447701730.011
morphogenesis of a polarized epitheliumGO:000173830.011
regulation of cytoplasmic transportGO:19036491490.011
prostate gland developmentGO:003085030.011
negative regulation of cell motilityGO:20001461040.011
lymphocyte activationGO:00466491330.011
divalent metal ion transportGO:00708381520.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
positive regulation of mapk cascadeGO:00434101900.011
neuromuscular process controlling balanceGO:005088570.011
Mouse
immune system developmentGO:00025201950.011
myoblast fusionGO:000752010.011
inorganic cation transmembrane transportGO:00986621940.011
positive regulation of nucleotide catabolic processGO:00308131850.011
positive regulation of gtpase activityGO:00435471660.011
vasculature developmentGO:00019441810.011
regulation of neural precursor cell proliferationGO:200017740.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
thymus developmentGO:004853830.011
protein targetingGO:00066051870.011
mitotic cell cycle phase transitionGO:00447721620.011
angiogenesisGO:00015251470.011
motor neuron axon guidanceGO:000804520.011
organ formationGO:004864530.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
Mouse
lipid transportGO:0006869900.011
cell fate determinationGO:000170930.011
neuroblast proliferationGO:000740540.011
negative regulation of protein processingGO:00109551420.011
regulation of synaptic plasticityGO:004816730.011
cerebellum developmentGO:002154920.011
blood vessel developmentGO:00015681720.011
epithelial tube branching involved in lung morphogenesisGO:006044140.011
calcium ion homeostasisGO:00550741220.011
cellular response to lipidGO:00713961270.011
endochondral bone morphogenesisGO:006035030.011
regulation of locomotionGO:00400123290.011
blood vessel morphogenesisGO:00485141620.011
salivary gland morphogenesisGO:000743540.011
negative regulation of cellular component movementGO:00512711060.011
visual behaviorGO:000763220.011
regulation of lymphocyte activationGO:00512491030.011
protein dephosphorylationGO:0006470810.011
single organism reproductive processGO:0044702980.011
sensory perception of smellGO:000760820.010
circadian behaviorGO:004851220.010
response to cytokineGO:00340972320.010
nuclear transportGO:00511691790.010
i kappab kinase nf kappab signalingGO:00072491660.010
t cell differentiation in thymusGO:003307740.010
epithelium migrationGO:00901321190.010
cardiovascular system developmentGO:00723582620.010
organelle assemblyGO:00709251760.010
cellular response to growth factor stimulusGO:00713631970.010
positive regulation of locomotionGO:00400171860.010
negative regulation of proteolysisGO:00458611320.010
sequestering of calcium ionGO:0051208170.010
central nervous system developmentGO:00074171230.010
striated muscle contractionGO:0006941520.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
calcium ion transportGO:00068161470.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
positive regulation of cell migrationGO:00303351720.010
regulation of endopeptidase activityGO:00525481700.010
negative regulation of cell cycle processGO:00109481210.010
sex determinationGO:000753030.010
negative regulation of cell cycleGO:00457861930.010
regulation of protein processingGO:00706131500.010
sleepGO:003043120.010
regulation of cell differentiationGO:00455953930.010
spinal cord developmentGO:002151040.010
nucleotide biosynthetic processGO:00091651090.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
protein secretionGO:0009306980.010
meiosis iGO:000712740.010
neuromuscular processGO:0050905150.010
Mouse
response to oxidative stressGO:00069791210.010

HEXA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.584
inherited metabolic disorderDOID:6552420.584
lysosomal storage diseaseDOID:3211470.436
lipid storage diseaseDOID:9455280.082
nervous system diseaseDOID:8634310.076
central nervous system diseaseDOID:3311860.076
brain diseaseDOID:936730.044
cerebral degenerationDOID:1443160.044
musculoskeletal system diseaseDOID:172230.032
sensory system diseaseDOID:00501552030.020
disease of cellular proliferationDOID:145661740.018
immune system diseaseDOID:29141550.018
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.016
neurodegenerative diseaseDOID:12891020.016
cancerDOID:1621670.016
organ system cancerDOID:00506861640.015
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
retinal diseaseDOID:56791180.014
disease of mental healthDOID:150700.013
retinal degenerationDOID:8466890.012
cardiovascular system diseaseDOID:12871060.011
myopathyDOID:4231040.011
sphingolipidosisDOID:1927140.006
gangliosidosisDOID:236840.002
gangliosidosis gm2DOID:332130.001