Homo sapiens

285 known processes

EZH2

enhancer of zeste homolog 2 (Drosophila)

(Aliases: ENX-1,MGC9169,KMT6,ENX1,EZH1,KMT6A)

EZH2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of histone h3 k27 methylationGO:006108540.998
chromatin modificationGO:00165682980.996
methylation dependent chromatin silencingGO:000634630.995
covalent chromatin modificationGO:00165692540.984
chromatin organizationGO:00063253510.980
macromolecule methylationGO:0043414970.975
histone modificationGO:00165702510.958
histone lysine methylationGO:0034968500.948
methylationGO:00322591060.934
post embryonic developmentGO:000979120.836
Worm
purine ribonucleoside metabolic processGO:00461284370.762
negative regulation of histone methylationGO:003106160.741
nuclear divisionGO:00002801280.698
cellular response to growth factor stimulusGO:00713631970.668
negative regulation of protein metabolic processGO:00512483910.629
positive regulation of cellular component organizationGO:00511303760.609
cellular amino acid metabolic processGO:00065201160.607
protein alkylationGO:0008213740.598
negative regulation of developmental processGO:00510932470.587
Mouse Worm
gene silencingGO:0016458490.577
regulation of dna metabolic processGO:00510521530.547
vesicle mediated transportGO:00161923710.546
protein ubiquitinationGO:00165673140.545
negative regulation of protein modification processGO:00314002000.528
embryo developmentGO:00097901230.513
Fly
rostrocaudal neural tube patterningGO:002190310.505
negative regulation of histone h3 k9 methylationGO:005157330.502
regulation of histone methylationGO:0031060160.502
neurogenesisGO:00220081690.498
Mouse Fly
positive regulation of histone methylationGO:0031062120.498
positive regulation of histone h3 k4 methylationGO:005157180.469
positive regulation of organelle organizationGO:00106381950.459
regulation of cell cycleGO:00517263930.457
Mouse
response to abiotic stimulusGO:00096283360.409
regulation of chromatin modificationGO:1903308510.397
oogenesisGO:004847720.395
small gtpase mediated signal transductionGO:0007264780.395
mrna metabolic processGO:00160711750.390
muscle structure developmentGO:0061061980.388
Mouse Fly
sulfur compound metabolic processGO:00067901010.366
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.363
response to radiationGO:00093141510.357
regulation of cell cycle processGO:00105642660.356
Mouse
positive regulation of chromosome organizationGO:2001252410.341
cell morphogenesis involved in differentiationGO:00009041440.326
cellular component morphogenesisGO:00329893140.304
negative regulation of cellular protein metabolic processGO:00322693530.287
positive regulation of histone modificationGO:0031058290.282
negative regulation of cell differentiationGO:00455961710.275
Mouse
receptor mediated endocytosisGO:0006898840.263
negative regulation of cellular component organizationGO:00511292350.252
response to biotic stimulusGO:00096072760.251
nervous system developmentGO:00073992930.243
Mouse Fly
dna hypermethylationGO:004402610.243
organ morphogenesisGO:00098871470.241
regulation of meiotic cell cycleGO:005144540.237
multicellular organismal agingGO:001025930.236
Worm
protein methylationGO:0006479740.226
cell morphogenesisGO:00009022960.216
cellular response to oxygen containing compoundGO:19017012760.216
Mouse
single organism cellular localizationGO:19025803320.213
response to oxygen containing compoundGO:19017003690.211
Mouse
protein modification by small protein conjugationGO:00324463420.207
tube developmentGO:00352951250.197
cell developmentGO:00484683280.195
oocyte differentiationGO:000999420.193
mitotic cell cycleGO:00002783260.184
Mouse Fly
histone methylationGO:0016571600.170
response to ionizing radiationGO:0010212650.168
myeloid cell differentiationGO:00300991170.164
cell projection organizationGO:00300302520.162
Fly
ras protein signal transductionGO:0007265730.159
cell part morphogenesisGO:00329901370.153
Fly
rna processingGO:00063962550.148
single organism reproductive processGO:0044702980.142
Worm
reproductive system developmentGO:0061458560.138
cytoplasmic transportGO:00164823790.132
dna repairGO:00062811980.130
regulation of gene expression epigeneticGO:0040029730.125
internal protein amino acid acetylationGO:00064751010.118
enzyme linked receptor protein signaling pathwayGO:00071673030.117
regulation of cell differentiationGO:00455953930.117
alpha amino acid metabolic processGO:1901605720.117
dna methylation on cytosineGO:003277630.116
negative regulation of chromatin modificationGO:1903309210.113
generation of neuronsGO:00486991520.112
Mouse Fly
regulation of cell developmentGO:00602841610.110
cell divisionGO:00513011680.105
Worm
neuron differentiationGO:00301821380.104
Fly
microtubule cytoskeleton organizationGO:00002261760.100
response to external biotic stimulusGO:00432072610.099
microtubule based processGO:00070172100.098
purine nucleoside triphosphate metabolic processGO:00091444120.097
coenzyme metabolic processGO:0006732650.097
chromatin remodelingGO:0006338550.095
regulation of nervous system developmentGO:0051960880.090
Mouse
cellular modified amino acid metabolic processGO:0006575640.090
blastocyst developmentGO:000182430.090
positive regulation of cell cycleGO:00457871400.089
sex differentiationGO:0007548450.088
reproductionGO:0000003630.087
Worm
posttranscriptional regulation of gene expressionGO:00106082130.087
actin filament based processGO:00300292240.085
neuron developmentGO:00486661130.085
Fly
rna splicingGO:00083801310.085
response to growth factorGO:00708482050.084
mrna processingGO:00063971330.084
endocytosisGO:00068971590.083
histone h3 k4 methylationGO:0051568270.083
regulation of cellular amine metabolic processGO:0033238110.082
oocyte developmentGO:004859910.081
negative regulation of chromosome organizationGO:2001251480.079
positive regulation of chromatin modificationGO:1903310300.075
negative regulation of cell cycleGO:00457861930.075
Mouse
positive regulation of cell cycle processGO:00900681060.072
regulation of meiosisGO:004002030.071
neuron projection morphogenesisGO:0048812500.071
Fly
histone h3 k9 methylationGO:0051567100.069
Fly
regulation of cellular response to stressGO:00801352440.069
response to lipidGO:00339932060.069
response to bacteriumGO:00096171440.068
female gamete generationGO:000729220.066
mitotic nuclear divisionGO:00070671190.065
response to drugGO:0042493810.065
cellular response to oxygen levelsGO:0071453550.064
chromatin silencingGO:0006342120.063
cellular macromolecular complex assemblyGO:00346223240.061
sodium ion export from cellGO:003637660.061
protein acylationGO:00435431380.060
response to lead ionGO:001028810.059
determination of adult lifespanGO:000834020.057
Worm
embryo development ending in birth or egg hatchingGO:0009792340.057
response to alcoholGO:0097305640.056
regulation of chromosome organizationGO:00330441030.054
peptidyl lysine acetylationGO:00183941010.053
response to activityGO:001482300.053
regulation of circadian rhythmGO:0042752110.052
negative regulation of multicellular organismal processGO:00512413170.051
Mouse Worm
gamete generationGO:0007276250.050
Worm
cellular response to endogenous stimulusGO:00714953360.050
dna conformation changeGO:00711031130.049
cellular protein catabolic processGO:00442572610.048
cellular response to dna damage stimulusGO:00069743790.047
regulation of small gtpase mediated signal transductionGO:00510561560.047
organelle fissionGO:00482851490.047
response to hyperoxiaGO:005509340.046
negative regulation of programmed cell deathGO:00430693210.046
response to acid chemicalGO:0001101660.046
regulation of kinase activityGO:00435493140.044
cartilage developmentGO:0051216310.043
muscle cell differentiationGO:0042692630.042
Mouse
regulation of multi organism processGO:00439001570.042
regulation of mitotic recombinationGO:000001910.042
dendrite developmentGO:0016358240.040
Fly
mrna splicing via spliceosomeGO:0000398890.040
negative regulation of cell deathGO:00605483450.040
cellular macromolecule catabolic processGO:00442653800.039
nitrogen compound transportGO:00717051910.039
positive regulation of histone h3 k27 methylationGO:006108730.039
response to other organismGO:00517072610.038
cellular response to lipidGO:00713961270.038
response to fungusGO:000962040.037
regionalizationGO:0003002290.037
cellular response to acid chemicalGO:0071229440.036
neuron projection developmentGO:00311751060.035
Fly
response to decreased oxygen levelsGO:0036293960.035
histone h3 k9 modificationGO:0061647110.034
Fly
response to steroid hormoneGO:0048545800.034
regulation of transferase activityGO:00513383550.034
cardiovascular system developmentGO:00723582620.033
pattern specification processGO:0007389430.033
negative regulation of apoptotic processGO:00430663160.032
maintenance of locationGO:00512351120.032
cell morphogenesis involved in neuron differentiationGO:0048667440.032
Fly
meiotic cell cycleGO:0051321130.032
dna methylationGO:000630670.032
Mouse
dephosphorylationGO:00163112090.031
maintenance of protein location in cellGO:0032507560.031
response to hypoxiaGO:0001666960.031
negative regulation of gene expression epigeneticGO:0045814190.031
reproductive structure developmentGO:0048608550.031
locomotory behaviorGO:000762610.030
sensory organ morphogenesisGO:0090596210.030
atp catabolic processGO:00062001570.030
regulation of mrna splicing via spliceosomeGO:0048024320.029
histone ubiquitinationGO:0016574310.029
positive regulation of developmental processGO:00510943140.029
regulation of cellular response to growth factor stimulusGO:0090287760.029
regulation of dna replicationGO:0006275680.029
negative regulation of catalytic activityGO:00430863350.029
regulation of protein transportGO:00512232130.029
response to extracellular stimulusGO:0009991850.029
protein catabolic processGO:00301633250.029
spindle organizationGO:0007051530.028
defense response to other organismGO:00985421290.028
immune effector processGO:00022521590.028
modification dependent protein catabolic processGO:00199412090.028
defense response to fungusGO:005083240.028
cell cycle phase transitionGO:00447701730.028
Mouse
cellular ketone metabolic processGO:0042180800.027
regulation of mitotic cell cycleGO:00073461890.027
Mouse
mitotic cell cycle processGO:19030472860.026
Mouse
agingGO:0007568660.026
Worm
regulation of protein localizationGO:00328802960.026
regulation of response to external stimulusGO:00321012220.026
tube morphogenesisGO:0035239950.026
purine nucleoside catabolic processGO:00061523980.025
regulation of histone modificationGO:0031056470.025
chordate embryonic developmentGO:0043009340.025
gland developmentGO:0048732480.024
cellular response to organonitrogen compoundGO:00714171240.024
amine metabolic processGO:0009308440.024
positive regulation of dna metabolic processGO:0051054730.024
protein importGO:00170381300.024
positive regulation of immune system processGO:00026842830.024
cellular response to steroid hormone stimulusGO:0071383370.024
regulation of dna repairGO:0006282470.024
regulation of nuclear divisionGO:0051783650.024
response to molecule of bacterial originGO:0002237820.024
developmental process involved in reproductionGO:0003006660.023
Worm
regulation of histone h3 k4 methylationGO:0051569100.023
organelle assemblyGO:00709251760.023
response to vitaminGO:0033273130.023
regulation of ras protein signal transductionGO:00465781550.022
intrinsic apoptotic signaling pathwayGO:00971931270.022
digestive tract developmentGO:0048565750.022
cellular response to dexamethasone stimulusGO:007154910.022
regulation of cellular component biogenesisGO:00440872810.022
response to nitrogen compoundGO:19016981840.022
biological adhesionGO:00226103310.022
cofactor metabolic processGO:0051186870.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.022
cell adhesionGO:00071553250.021
reproductive processGO:00224141060.021
Worm
negative regulation of protein phosphorylationGO:00019331400.020
viral processGO:00160321460.020
signal transduction by phosphorylationGO:00230142970.020
response to caffeineGO:003100030.020
adaptive immune responseGO:0002250490.019
negative regulation of transferase activityGO:00513481240.019
multicellular organismal reproductive processGO:0048609400.019
Worm
epidermis developmentGO:0008544590.019
Mouse
histone acetylationGO:0016573930.018
regulation of protein serine threonine kinase activityGO:00719001790.018
cell projection morphogenesisGO:00488581290.018
Fly
regulation of dna methylationGO:004403020.018
hemopoiesisGO:00300971800.017
angiogenesisGO:00015251470.017
atp metabolic processGO:00460341760.017
membrane organizationGO:00610242920.017
positive regulation of cell differentiationGO:00455972110.017
regulation of mrna metabolic processGO:1903311530.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
response to dexamethasoneGO:007154810.017
hepaticobiliary system developmentGO:0061008100.017
dosage compensationGO:000754930.017
vasculature developmentGO:00019441810.016
oocyte maturationGO:000155610.016
system processGO:00030083490.016
posttranscriptional gene silencingGO:0016441250.016
multi organism cellular processGO:00447641560.016
regulation of immune responseGO:00507762010.016
positive regulation of cell proliferationGO:00082843010.016
negative regulation of protein maturationGO:19033181420.015
mitotic cytokinesisGO:0000281190.015
hindbrain developmentGO:003090230.015
Mouse
response to hormoneGO:00097251750.015
striated muscle cell differentiationGO:0051146430.015
Mouse
cell activationGO:00017752130.015
regulation of protein kinase activityGO:00458592890.015
nucleoside phosphate catabolic processGO:19012924120.015
spermatid differentiationGO:004851540.015
growthGO:00400072020.015
Mouse
nucleotide catabolic processGO:00091664080.015
regulation of locomotionGO:00400123290.015
nucleoside triphosphate metabolic processGO:00091414220.014
multicellular organism reproductionGO:0032504420.014
Worm
nucleoside triphosphate catabolic processGO:00091433940.014
cellular response to transforming growth factor beta stimulusGO:0071560940.014
gonad developmentGO:0008406340.014
cellular response to nitrogen compoundGO:19016991440.014
negative regulation of organelle organizationGO:00106391260.014
male gamete generationGO:0048232220.014
regulation of chromatin organizationGO:1902275560.014
peptidyl lysine modificationGO:00182051440.014
Fly
lipid localizationGO:00108761060.014
regulation of chromosome segregationGO:0051983440.014
regulation of neurogenesisGO:0050767820.014
Mouse
ribonucleoside monophosphate catabolic processGO:00091581580.014
response to transforming growth factor betaGO:0071559940.014
oxidation reduction processGO:00551143960.014
purine containing compound catabolic processGO:00725234110.013
regulation of protein complex assemblyGO:00432541470.013
endomembrane system organizationGO:00102561960.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
regulation of cell activationGO:00508651250.013
negative regulation of hydrolase activityGO:00513461820.013
leukocyte proliferationGO:0070661740.013
rna splicing via transesterification reactionsGO:0000375900.013
developmental maturationGO:0021700280.013
sex determinationGO:000753030.013
response to purine containing compoundGO:0014074400.013
eye developmentGO:0001654420.013
negative regulation of neuron projection developmentGO:0010977150.013
spermatid developmentGO:000728640.013
neuromuscular junction developmentGO:000752830.012
positive regulation of nfat protein import into nucleusGO:005153330.012
regulation of adaptive immune responseGO:0002819330.012
intracellular protein transportGO:00068862700.012
sexual reproductionGO:0019953370.012
Worm
negative regulation of phosphate metabolic processGO:00459362670.012
cellular response to hormone stimulusGO:00328701250.012
immune system developmentGO:00025201950.012
regulation of dna dependent dna replicationGO:0090329190.012
glycosyl compound catabolic processGO:19016584130.012
single organism carbohydrate metabolic processGO:00447231930.012
regulation of actin filament based processGO:00329701410.012
development of primary sexual characteristicsGO:0045137350.012
apoptotic signaling pathwayGO:00971902680.011
negative regulation of kinase activityGO:00336731060.011
protein dephosphorylationGO:0006470810.011
cell type specific apoptotic processGO:00972851250.011
circulatory system developmentGO:00723592620.011
ribonucleotide catabolic processGO:00092614050.011
regulation of protein catabolic processGO:00421761550.011
response to toxic substanceGO:0009636370.011
establishment of protein localization to organelleGO:00725941720.011
positive regulation of phosphorylationGO:00423273940.011
regulation of cellular ketone metabolic processGO:0010565500.011
regulation of neuron differentiationGO:0045664700.011
regulation of mrna processingGO:0050684480.011
negative regulation of phosphorylationGO:00423261740.011
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
response to amino acidGO:0043200140.011
regulation of cellular component movementGO:00512703340.010
regulation of oocyte developmentGO:006028110.010
negative regulation of multi organism processGO:0043901920.010
dna modificationGO:0006304270.010
Mouse
muscle system processGO:0003012810.010
protein complex localizationGO:0031503310.010
dna replicationGO:00062601160.010
regulation of cell divisionGO:00513021160.010

EZH2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:870520.606
peripheral neuropathyDOID:0060053120.606
nervous system diseaseDOID:8634310.606
immune system diseaseDOID:29141550.020
hematopoietic system diseaseDOID:741000.011
physical disorderDOID:0080015410.001