Homo sapiens

236 known processes

PFN2

profilin 2

(Aliases: D3S1319E,PFL)

PFN2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of protein localization to membraneGO:00901501210.294
single organism cellular localizationGO:19025803320.190
nucleoside catabolic processGO:00091644080.188
protein localization to membraneGO:00726571600.181
single organism membrane organizationGO:00448022680.178
anatomical structure formation involved in morphogenesisGO:00486462840.170
neuromuscular junction developmentGO:000752830.168
protein localization to plasma membraneGO:0072659930.164
nervous system developmentGO:00073992930.145
cell developmentGO:00484683280.141
purine ribonucleoside metabolic processGO:00461284370.140
ribonucleoside monophosphate catabolic processGO:00091581580.137
membrane organizationGO:00610242920.136
purine nucleoside triphosphate catabolic processGO:00091463920.127
motor neuron axon guidanceGO:000804520.117
regulation of cellular ketone metabolic processGO:0010565500.112
establishment of protein localization to plasma membraneGO:0090002680.101
protein polyubiquitinationGO:00002091100.099
cellular amino acid metabolic processGO:00065201160.099
nucleotide catabolic processGO:00091664080.095
protein catabolic processGO:00301633250.094
cellular macromolecule catabolic processGO:00442653800.091
regulation of cell cycleGO:00517263930.089
protein modification by small protein conjugationGO:00324463420.087
cell projection organizationGO:00300302520.087
post embryonic developmentGO:000979120.086
glycosyl compound catabolic processGO:19016584130.086
plasma membrane organizationGO:00070091150.085
purine ribonucleotide catabolic processGO:00091544040.084
proteolysis involved in cellular protein catabolic processGO:00516032440.083
wnt signaling pathwayGO:00160551560.081
intracellular protein transportGO:00068862700.079
nucleoside triphosphate catabolic processGO:00091433940.076
golgi vesicle transportGO:0048193800.076
vesicle mediated transportGO:00161923710.076
Mouse
cell morphogenesis involved in differentiationGO:00009041440.075
purine ribonucleoside monophosphate catabolic processGO:00091691580.074
protein ubiquitinationGO:00165673140.074
cytoplasmic transportGO:00164823790.071
regulation of cell migrationGO:00303342890.071
negative regulation of protein metabolic processGO:00512483910.070
nucleoside triphosphate metabolic processGO:00091414220.068
regulation of cellular amino acid metabolic processGO:000652160.065
morphogenesis of embryonic epitheliumGO:001633140.065
cellular ketone metabolic processGO:0042180800.064
protein k48 linked ubiquitinationGO:0070936380.062
regulation of cell motilityGO:20001452990.061
cellular component morphogenesisGO:00329893140.060
regulation of cellular amine metabolic processGO:0033238110.059
neuron differentiationGO:00301821380.059
ubiquitin dependent protein catabolic processGO:00065112060.059
post golgi vesicle mediated transportGO:0006892360.059
negative regulation of cellular protein metabolic processGO:00322693530.058
chemical homeostasisGO:00488783060.056
embryonic epithelial tube formationGO:000183840.056
regulation of cellular component sizeGO:0032535820.055
cellular protein catabolic processGO:00442572610.055
dephosphorylationGO:00163112090.054
modification dependent macromolecule catabolic processGO:00436322120.053
positive regulation of cellular component organizationGO:00511303760.052
epithelium developmentGO:00604292270.051
compound eye developmentGO:004874910.051
negative regulation of programmed cell deathGO:00430693210.051
synaptic vesicle endocytosisGO:004848820.051
modification dependent protein catabolic processGO:00199412090.051
cellular amine metabolic processGO:0044106410.050
ras protein signal transductionGO:0007265730.049
negative regulation of cellular amine metabolic processGO:003323930.049
negative regulation of apoptotic processGO:00430663160.048
nucleoside monophosphate metabolic processGO:00091231910.048
regulation of cell developmentGO:00602841610.047
purine nucleoside triphosphate metabolic processGO:00091444120.047
neuron developmentGO:00486661130.046
negative regulation of locomotionGO:00400131180.046
cerebellum developmentGO:002154920.046
regulation of neuron differentiationGO:0045664700.046
actin cytoskeleton organizationGO:00300362070.045
positive regulation of organelle organizationGO:00106381950.045
endomembrane system organizationGO:00102561960.045
canonical wnt signaling pathwayGO:00600701160.045
cellular response to dna damage stimulusGO:00069743790.045
neurogenesisGO:00220081690.045
ribonucleoside triphosphate metabolic processGO:00091994120.045
ribonucleoside triphosphate catabolic processGO:00092033910.044
mechanosensory behaviorGO:000763840.044
mitotic cell cycle processGO:19030472860.043
oogenesisGO:004847720.043
single organism carbohydrate metabolic processGO:00447231930.043
cellular response to oxygen containing compoundGO:19017012760.043
negative regulation of catalytic activityGO:00430863350.043
posttranscriptional regulation of gene expressionGO:00106082130.043
negative regulation of cellular component movementGO:00512711060.042
anterior posterior axis specificationGO:000994820.042
regulation of protein complex assemblyGO:00432541470.042
tissue migrationGO:00901301190.042
purine nucleotide catabolic processGO:00061954050.042
apoptotic signaling pathwayGO:00971902680.041
carbohydrate metabolic processGO:00059752070.040
regulation of actin cytoskeleton organizationGO:00329561160.040
actin filament based processGO:00300292240.040
organ morphogenesisGO:00098871470.039
regulation of cell projection organizationGO:00313441070.039
regulation of actin filament based processGO:00329701410.039
ion homeostasisGO:00508012300.039
locomotory behaviorGO:000762610.039
negative regulation of cell deathGO:00605483450.039
negative regulation of developmental processGO:00510932470.038
cellular macromolecular complex assemblyGO:00346223240.038
epithelium migrationGO:00901321190.037
regulation of cell differentiationGO:00455953930.037
generation of neuronsGO:00486991520.037
amine metabolic processGO:0009308440.036
secretion by cellGO:00329402260.036
Mouse
negative regulation of cellular amino acid metabolic processGO:004576320.036
metencephalon developmentGO:002203720.036
mitotic cell cycleGO:00002783260.035
regulation of cell morphogenesisGO:00226041530.035
regenerationGO:003109940.035
negative regulation of multicellular organismal processGO:00512413170.035
purine nucleoside catabolic processGO:00061523980.034
neural tube formationGO:000184130.034
cell divisionGO:00513011680.034
angiogenesisGO:00015251470.033
chromosome segregationGO:00070591140.033
negative regulation of cellular component organizationGO:00511292350.033
axon cargo transportGO:000808820.033
negative regulation of phosphorus metabolic processGO:00105632670.033
regulation of nervous system developmentGO:0051960880.033
photoreceptor cell differentiationGO:004653020.032
regulation of epithelial cell migrationGO:0010632930.032
single organismal cell cell adhesionGO:00163371480.032
blood vessel morphogenesisGO:00485141620.032
purine nucleoside monophosphate catabolic processGO:00091281580.032
cellular response to oxidative stressGO:0034599850.032
protein localization to organelleGO:00333652800.031
intrinsic apoptotic signaling pathwayGO:00971931270.031
ribonucleoside catabolic processGO:00424544060.031
regulation of wnt signaling pathwayGO:00301111230.031
regulation of locomotionGO:00400123290.030
chromatin modificationGO:00165682980.030
cation transportGO:00068123310.030
cell morphogenesisGO:00009022960.030
nucleosome organizationGO:0034728660.030
female gamete generationGO:000729220.030
single organism reproductive processGO:0044702980.030
regulation of apoptotic signaling pathwayGO:20012331750.029
neurotransmitter secretionGO:000726940.029
Mouse
secretionGO:00469032540.029
Mouse
system processGO:00030083490.029
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.029
cytokinesisGO:0000910960.029
nucleoside monophosphate catabolic processGO:00091251590.029
negative regulation of phosphate metabolic processGO:00459362670.028
purine nucleoside monophosphate metabolic processGO:00091261860.028
positive regulation of cell migrationGO:00303351720.028
Human
regulation of anatomical structure morphogenesisGO:00226032860.027
biological adhesionGO:00226103310.027
blood vessel developmentGO:00015681720.027
response to abiotic stimulusGO:00096283360.027
regulation of axon guidanceGO:190266730.027
neurological system processGO:00508771630.027
organonitrogen compound biosynthetic processGO:19015662000.027
retinal ganglion cell axon guidanceGO:003129020.027
regulation of cell cycle processGO:00105642660.027
regulation of neural precursor cell proliferationGO:200017740.027
metal ion transportGO:00300012720.027
synaptic vesicle recyclingGO:003646530.026
positive regulation of cytoskeleton organizationGO:0051495830.026
positive regulation of canonical wnt signaling pathwayGO:0090263330.026
regulation of transferase activityGO:00513383550.026
associative learningGO:000830610.026
response to oxygen containing compoundGO:19017003690.026
l amino acid importGO:004309240.026
negative regulation of protein modification processGO:00314002000.026
determination of adult lifespanGO:000834020.026
atp catabolic processGO:00062001570.026
head developmentGO:00603221080.026
negative regulation of protein phosphorylationGO:00019331400.026
positive regulation of locomotionGO:00400171860.026
Human
regulation of kinase activityGO:00435493140.026
epithelial cell migrationGO:00106311190.026
positive regulation of apoptotic processGO:00430652460.025
nucleoside phosphate catabolic processGO:19012924120.025
cation transmembrane transportGO:00986552380.025
reproductive processGO:00224141060.025
dna repairGO:00062811980.025
cellular response to transforming growth factor beta stimulusGO:0071560940.025
spinal cord developmentGO:002151040.025
regulation of cellular component biogenesisGO:00440872810.025
divalent inorganic cation transportGO:00725111580.024
cell part morphogenesisGO:00329901370.024
cell cell signalingGO:00072671550.024
Mouse
cardiovascular system developmentGO:00723582620.024
positive regulation of cellular component movementGO:00512721810.024
Human
negative regulation of cell motilityGO:20001461040.024
regulation of actin filament lengthGO:0030832560.024
cellular response to growth factor stimulusGO:00713631970.024
circulatory system developmentGO:00723592620.024
cell projection assemblyGO:00300311260.024
regulation of neurogenesisGO:0050767820.024
regulation of membrane potentialGO:0042391950.024
alpha amino acid metabolic processGO:1901605720.024
cell adhesionGO:00071553250.023
regulation of canonical wnt signaling pathwayGO:0060828880.023
protein maturationGO:00516042330.023
cell projection morphogenesisGO:00488581290.023
ribonucleoside monophosphate metabolic processGO:00091611870.023
rna interferenceGO:001624640.023
segmentationGO:003528240.023
negative regulation of apoptotic signaling pathwayGO:2001234970.023
purine ribonucleoside catabolic processGO:00461303980.023
positive regulation of cellular amine metabolic processGO:003324070.023
central nervous system developmentGO:00074171230.022
negative regulation of phosphorylationGO:00423261740.022
regulation of cytoskeleton organizationGO:00514931770.022
protein polymerizationGO:0051258710.022
ribonucleotide catabolic processGO:00092614050.022
regulation of protein kinase activityGO:00458592890.022
divalent metal ion transportGO:00708381520.022
small gtpase mediated signal transductionGO:0007264780.022
axon regenerationGO:003110310.022
actin filament organizationGO:00070151280.022
regulation of proteolysisGO:00301622930.022
growthGO:00400072020.021
limbic system developmentGO:002176130.021
positive regulation of cellular component biogenesisGO:00440891580.021
positive regulation of cell proliferationGO:00082843010.021
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.021
meiotic chromosome segregationGO:004513240.021
endosomal transportGO:00161971290.021
negative regulation of hydrolase activityGO:00513461820.021
response to radiationGO:00093141510.021
regulation of dephosphorylationGO:0035303960.021
regulation of protein polymerizationGO:0032271630.021
adult locomotory behaviorGO:000834410.021
regulation of phosphatase activityGO:0010921810.021
regulation of vesicle mediated transportGO:00606271300.020
Mouse
protein k33 linked ubiquitinationGO:199039010.020
sensory perceptionGO:00076001030.020
proteasomal protein catabolic processGO:00104981760.020
calcium ion transmembrane transportGO:0070588760.020
epithelial cell differentiationGO:00308551410.020
golgi to plasma membrane protein transportGO:0043001190.020
organelle fissionGO:00482851490.020
urea metabolic processGO:001962730.020
muscle structure developmentGO:0061061980.020
monocarboxylic acid metabolic processGO:00327871850.020
actin polymerization or depolymerizationGO:0008154560.020
small molecule biosynthetic processGO:00442831570.020
ameboidal type cell migrationGO:00016671350.020
regulation of actin filament polymerizationGO:0030833500.019
organelle assemblyGO:00709251760.019
organelle localizationGO:0051640840.019
Mouse
positive regulation of phosphorylationGO:00423273940.019
negative regulation of intracellular signal transductionGO:19025321830.019
blastoderm segmentationGO:000735020.019
male meiosisGO:000714010.019
positive regulation of cell motilityGO:20001471770.019
Human
positive regulation of cell differentiationGO:00455972110.019
monovalent inorganic cation transportGO:00156721280.019
chromatin organizationGO:00063253510.019
proteasomal ubiquitin independent protein catabolic processGO:001049930.018
purine containing compound catabolic processGO:00725234110.018
single organism cell adhesionGO:00986021790.018
positive regulation of cell deathGO:00109422630.018
glycoprotein biosynthetic processGO:0009101910.018
organophosphate catabolic processGO:00464344300.018
vasculature developmentGO:00019441810.018
distal tubule developmentGO:007201740.018
hindbrain developmentGO:003090230.018
sodium ion transportGO:0006814610.018
negative regulation of cell proliferationGO:00082852280.018
protein dna complex subunit organizationGO:0071824800.018
regulation of peptidase activityGO:00525471800.018
establishment of organelle localizationGO:0051656590.018
Mouse
gtp metabolic processGO:00460392390.017
innate immune responseGO:00450871780.017
negative regulation of phosphatase activityGO:0010923610.017
ion transmembrane transportGO:00342203380.017
regulation of anatomical structure sizeGO:00900661010.017
protein autoubiquitinationGO:0051865370.017
regulation of synaptic plasticityGO:004816730.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
regulation of cellular response to stressGO:00801352440.017
positive regulation of kinase activityGO:00336742040.017
response to oxidative stressGO:00069791210.017
actin filament based movementGO:0030048170.017
renal system developmentGO:0072001630.017
regulation of reactive oxygen species metabolic processGO:2000377410.017
response to growth factorGO:00708482050.017
regulation of vasculature developmentGO:1901342970.017
tube closureGO:006060630.016
mitotic cell cycle phase transitionGO:00447721620.016
regulation of cytokinesisGO:0032465450.016
positive regulation of protein polymerizationGO:0032273450.016
cation homeostasisGO:00550801890.016
establishment of protein localization to organelleGO:00725941720.016
cellular response to endogenous stimulusGO:00714953360.016
protein oligomerizationGO:00512591730.016
neuron projection regenerationGO:003110210.016
cell growthGO:00160491600.016
regulation of cell divisionGO:00513021160.016
guanosine containing compound catabolic processGO:19010692390.016
amino acid importGO:004309040.016
positive regulation of programmed cell deathGO:00430682490.016
monocarboxylic acid biosynthetic processGO:0072330670.016
tube morphogenesisGO:0035239950.016
translationGO:00064121320.016
behaviorGO:00076101120.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
negative regulation of organelle organizationGO:00106391260.016
establishment of vesicle localizationGO:0051650230.016
Mouse
response to axon injuryGO:004867810.016
positive regulation of nucleoside metabolic processGO:00459791860.016
maintenance of locationGO:00512351120.015
negative regulation of cell migrationGO:00303361020.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
positive regulation of transferase activityGO:00513472270.015
actin mediated cell contractionGO:0070252120.015
positive regulation of wnt signaling pathwayGO:0030177540.015
cell substrate adhesionGO:00315891320.015
regulation of mitotic cell cycleGO:00073461890.015
protein dephosphorylationGO:0006470810.015
lipid metabolic processGO:00066293810.015
regulation of neuron projection developmentGO:0010975570.015
regulation of protein maturationGO:19033171500.015
metal ion homeostasisGO:00550651690.015
regulation of protein localizationGO:00328802960.015
cardiac muscle adaptationGO:001488740.015
microtubule based processGO:00070172100.015
cell type specific apoptotic processGO:00972851250.015
protein processingGO:00164852260.015
renal sodium ion transportGO:000309620.015
carboxylic acid biosynthetic processGO:0046394970.015
membrane buddingGO:0006900280.015
cell agingGO:0007569520.015
nuclear divisionGO:00002801280.015
cellular carbohydrate metabolic processGO:0044262840.014
carboxylic acid transportGO:0046942630.014
immune responseGO:00069553070.014
somatic muscle developmentGO:000752510.014
embryonic camera type eye developmentGO:003107620.014
tissue morphogenesisGO:0048729960.014
regulation of cell shapeGO:0008360480.014
actin filament polymerizationGO:0030041450.014
negative regulation of protein processingGO:00109551420.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of protein processingGO:00706131500.014
negative regulation of cell cycleGO:00457861930.014
cell cycle phase transitionGO:00447701730.014
neural tube closureGO:000184330.014
spermatid differentiationGO:004851540.014
microtubule cytoskeleton organizationGO:00002261760.014
peripheral nervous system developmentGO:000742220.014
regulation of cell growthGO:00015581350.014
endocytosisGO:00068971590.014
protein targetingGO:00066051870.014
regulation of cell morphogenesis involved in differentiationGO:0010769830.014
ultradian rhythmGO:000762410.014
negative regulation of epithelial cell migrationGO:0010633380.014
cellular homeostasisGO:00197251960.013
positive regulation of cysteine type endopeptidase activityGO:2001056790.013
positive regulation of apoptotic signaling pathwayGO:2001235700.013
negative regulation of cell cycle phase transitionGO:1901988890.013
regulation of endopeptidase activityGO:00525481700.013
positive regulation of catabolic processGO:00098963100.013
nerve developmentGO:002167540.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of purine nucleotide metabolic processGO:19005422640.013
regulation of protein stabilityGO:0031647870.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of gtp catabolic processGO:00331241800.013
cell cycle checkpointGO:00000751170.013
regulation of endocytosisGO:0030100720.013
negative regulation of catabolic processGO:00098951040.013
guanosine containing compound metabolic processGO:19010682440.013
organic acid biosynthetic processGO:0016053970.013
regulation of neuroblast proliferationGO:190269230.013
positive regulation of peptidase activityGO:0010952880.013
organic anion transportGO:00157111030.013
taxisGO:00423301570.013
cardiac muscle cell contractionGO:008600340.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.013
primary neural tube formationGO:001402030.013
cell fate determinationGO:000170930.013
regulation of protein catabolic processGO:00421761550.013
amino acid transportGO:0006865280.013
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
nitrogen compound transportGO:00717051910.013
regulation of bindingGO:00510981110.013
embryonic eye morphogenesisGO:004804820.013
cell cycle g2 m phase transitionGO:0044839430.013
vesicle organizationGO:0016050620.013
enzyme linked receptor protein signaling pathwayGO:00071673030.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
golgi to plasma membrane transportGO:0006893210.012
vesicle targeting rough er to cis golgiGO:004820720.012
protein methylationGO:0006479740.012
negative regulation of angiogenesisGO:0016525390.012
urogenital system developmentGO:0001655650.012
regulation of cell cycle phase transitionGO:19019871260.012
embryonic placenta developmentGO:000189210.012
g2 m transition of mitotic cell cycleGO:0000086410.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
response to lipidGO:00339932060.012
anatomical structure homeostasisGO:00602491000.012
covalent chromatin modificationGO:00165692540.012
positive regulation of cell developmentGO:0010720920.012
carbohydrate biosynthetic processGO:0016051420.012
brain developmentGO:0007420970.012
renal sodium ion absorptionGO:007029420.012
gtp catabolic processGO:00061842370.012
organophosphate biosynthetic processGO:00904071630.012
establishment of nucleus localizationGO:004002310.012
neuron projection morphogenesisGO:0048812500.012
negative regulation of transferase activityGO:00513481240.012
response to organic cyclic compoundGO:00140702040.012
developmental process involved in reproductionGO:0003006660.012
positive regulation of nervous system developmentGO:0051962540.012
visual behaviorGO:000763220.012
endothelial cell migrationGO:0043542860.012
positive regulation of actin filament polymerizationGO:0030838380.012
cofactor metabolic processGO:0051186870.012
regulation of angiogenesisGO:0045765920.012
vesicle localizationGO:0051648260.012
Mouse
embryonic camera type eye morphogenesisGO:004859620.012
positive regulation of protein kinase activityGO:00458601900.012
signal releaseGO:0023061700.012
Mouse
rhythmic behaviorGO:000762220.012
response to other organismGO:00517072610.012
zymogen activationGO:0031638700.012
epithelial cell developmentGO:0002064340.012
regulation of transporter activityGO:0032409820.012
sulfur compound biosynthetic processGO:0044272380.012
regulation of ion transportGO:00432691890.012
spermatid developmentGO:000728640.011
anion transportGO:00068201610.011
nuclear transportGO:00511691790.011
response to biotic stimulusGO:00096072760.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
sensory organ developmentGO:0007423520.011
distal tubule morphogenesisGO:007215630.011
negative regulation of dephosphorylationGO:0035305630.011
rho protein signal transductionGO:0007266260.011
melanin metabolic processGO:000658210.011
negative regulation of growthGO:0045926970.011
internal peptidyl lysine acetylationGO:0018393970.011
autophagyGO:0006914880.011
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.011
anterior posterior axis specification embryoGO:000859520.011
regulation of ion transmembrane transportGO:00347651320.011
regulation of homeostatic processGO:00328441210.011
morphogenesis of an epitheliumGO:0002009600.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
regulation of response to dna damage stimulusGO:2001020940.011
actin filament bundle assemblyGO:0051017540.011
transforming growth factor beta receptor signaling pathwayGO:0007179760.011
negative regulation of protein maturationGO:19033181420.011
regulation of body fluid levelsGO:0050878990.011
regulation of protein serine threonine kinase activityGO:00719001790.011
positive regulation of synaptic transmissionGO:005080640.011
response to salt stressGO:000965130.011
ventricular septum morphogenesisGO:006041230.011
myosin filament assemblyGO:003103420.011
intracellular receptor signaling pathwayGO:00305221040.011
endothelial cell proliferationGO:0001935650.011
nucleocytoplasmic transportGO:00069131760.011
response to transforming growth factor betaGO:0071559940.011
defense responseGO:00069523150.011

PFN2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.075
Human
nervous system diseaseDOID:8634310.075
Human
sensory system diseaseDOID:00501552030.064
neuropathyDOID:870520.033
musculoskeletal system diseaseDOID:172230.029
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.019
auditory system diseaseDOID:2742530.019
inherited metabolic disorderDOID:6552420.018
disease of metabolismDOID:00146672950.018
nonsyndromic deafnessDOID:0050563500.016
retinal degenerationDOID:8466890.016
retinal diseaseDOID:56791180.016
muscle tissue diseaseDOID:661130.016
myopathyDOID:4231040.016
muscular diseaseDOID:00800001140.016
connective tissue diseaseDOID:651090.016
neurodegenerative diseaseDOID:12891020.015
Human
brain diseaseDOID:936730.014
bone diseaseDOID:0080001880.012
cardiovascular system diseaseDOID:12871060.011
disease of cellular proliferationDOID:145661740.011
cancerDOID:1621670.011