Homo sapiens

2 known processes

PPA1

pyrophosphatase (inorganic) 1

(Aliases: IOPPP,PP,MGC111556,PP1,SID6-8061)

PPA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytoplasmic transportGO:00164823790.444
negative regulation of cell deathGO:00605483450.341
cellular chemical homeostasisGO:00550821800.246
organophosphate catabolic processGO:00464344300.229
cellular amine metabolic processGO:0044106410.216
oxidation reduction processGO:00551143960.209
response to tumor cellGO:0002347100.206
secretionGO:00469032540.197
negative regulation of apoptotic processGO:00430663160.193
regulation of defense responseGO:00313471540.186
negative regulation of programmed cell deathGO:00430693210.182
cellular amino acid metabolic processGO:00065201160.172
amine metabolic processGO:0009308440.163
mitochondrion organizationGO:00070051560.160
regulation of nucleotide metabolic processGO:00061402690.138
purine containing compound catabolic processGO:00725234110.136
cellular response to oxidative stressGO:0034599850.116
response to other organismGO:00517072610.115
purine ribonucleotide catabolic processGO:00091544040.111
purine nucleotide catabolic processGO:00061954050.108
regulation of peptidase activityGO:00525471800.105
regulation of transferase activityGO:00513383550.103
sulfur compound metabolic processGO:00067901010.100
intracellular protein transportGO:00068862700.098
apoptotic signaling pathwayGO:00971902680.098
regulation of intracellular transportGO:00323861950.096
cellular homeostasisGO:00197251960.096
purine ribonucleoside metabolic processGO:00461284370.094
purine containing compound salvageGO:004310120.091
guanosine containing compound metabolic processGO:19010682440.089
positive regulation of apoptotic processGO:00430652460.084
response to biotic stimulusGO:00096072760.084
nucleotide catabolic processGO:00091664080.084
negative regulation of protein metabolic processGO:00512483910.083
nucleotide biosynthetic processGO:00091651090.083
cellular metabolic compound salvageGO:004309470.082
nucleoside phosphate catabolic processGO:19012924120.080
protein processingGO:00164852260.077
positive regulation of programmed cell deathGO:00430682490.077
purine ribonucleoside catabolic processGO:00461303980.077
positive regulation of cellular amine metabolic processGO:003324070.076
response to external biotic stimulusGO:00432072610.073
establishment of protein localization to organelleGO:00725941720.072
protein maturationGO:00516042330.072
purine nucleoside triphosphate metabolic processGO:00091444120.071
positive regulation of developmental processGO:00510943140.071
secretion by cellGO:00329402260.070
protein importGO:00170381300.070
innate immune responseGO:00450871780.070
Worm
positive regulation of cytokine productionGO:00018191670.069
post embryonic developmentGO:000979120.069
Worm
cellular modified amino acid metabolic processGO:0006575640.069
regulation of ion transportGO:00432691890.064
regulation of kinase activityGO:00435493140.064
protein targetingGO:00066051870.063
organonitrogen compound biosynthetic processGO:19015662000.063
regulation of response to external stimulusGO:00321012220.063
nitrogen compound transportGO:00717051910.063
regulation of cellular amine metabolic processGO:0033238110.062
positive regulation of cell deathGO:00109422630.062
purine ribonucleoside biosynthetic processGO:0046129230.059
regulation of protein localizationGO:00328802960.058
response to inorganic substanceGO:00100351270.058
negative regulation of cellular protein metabolic processGO:00322693530.058
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.057
regulation of response to woundingGO:19030341010.056
cell type specific apoptotic processGO:00972851250.055
regulation of proteolysisGO:00301622930.055
response to oxidative stressGO:00069791210.055
cellular response to cytokine stimulusGO:00713451810.054
nucleoside triphosphate catabolic processGO:00091433940.053
response to organonitrogen compoundGO:00102431560.052
transmembrane transportGO:00550853990.052
regulation of cytokine productionGO:00018172320.052
apoptotic mitochondrial changesGO:0008637570.051
regulation of purine nucleotide biosynthetic processGO:1900371500.051
nuclear transportGO:00511691790.051
regulation of apoptotic signaling pathwayGO:20012331750.050
response to organic cyclic compoundGO:00140702040.050
metal ion homeostasisGO:00550651690.049
locomotory behaviorGO:000762610.049
purine ribonucleotide biosynthetic processGO:0009152790.049
response to oxygen containing compoundGO:19017003690.047
positive regulation of transportGO:00510503360.046
nucleoside phosphate biosynthetic processGO:19012931090.043
ribonucleoside catabolic processGO:00424544060.043
regulation of cell cycleGO:00517263930.043
membrane organizationGO:00610242920.043
regulation of protein transportGO:00512232130.042
protein import into nucleusGO:00066061040.040
hindbrain developmentGO:003090230.040
single organism cellular localizationGO:19025803320.040
vesicle mediated transportGO:00161923710.039
organic acid biosynthetic processGO:0016053970.039
regulation of intracellular protein transportGO:00331571230.038
positive regulation of cell proliferationGO:00082843010.038
negative regulation of phosphate metabolic processGO:00459362670.038
nucleocytoplasmic transportGO:00069131760.038
response to abiotic stimulusGO:00096283360.038
negative regulation of transportGO:00510511760.037
response to woundingGO:00096111680.037
defense responseGO:00069523150.036
Worm
ribonucleoside triphosphate catabolic processGO:00092033910.036
immune response activating signal transductionGO:0002757900.036
alcohol metabolic processGO:00060661140.036
purine containing compound biosynthetic processGO:0072522880.036
epithelial cell differentiationGO:00308551410.036
single organism membrane organizationGO:00448022680.035
purine nucleoside triphosphate catabolic processGO:00091463920.035
response to nitrogen compoundGO:19016981840.035
regulation of cellular response to stressGO:00801352440.035
hemopoiesisGO:00300971800.035
gtp metabolic processGO:00460392390.035
nucleoside triphosphate metabolic processGO:00091414220.034
rna transportGO:0050658390.034
negative regulation of bindingGO:0051100570.034
purine nucleotide biosynthetic processGO:0006164840.034
protein secretionGO:0009306980.034
epithelium developmentGO:00604292270.033
cation homeostasisGO:00550801890.033
glycosyl compound catabolic processGO:19016584130.033
regulation of cellular amino acid metabolic processGO:000652160.033
purine ribonucleoside monophosphate metabolic processGO:00091671860.033
immune responseGO:00069553070.033
Worm
immune system developmentGO:00025201950.033
cellular ketone metabolic processGO:0042180800.033
regenerationGO:003109940.033
regulation of cell differentiationGO:00455953930.032
positive regulation of proteolysisGO:00458621420.032
cellular response to oxygen containing compoundGO:19017012760.032
cytokine productionGO:00018162470.032
tissue regenerationGO:004224630.032
regulation of endopeptidase activityGO:00525481700.032
positive regulation of nf kappab transcription factor activityGO:0051092810.031
negative regulation of immune system processGO:00026831360.031
nucleoside catabolic processGO:00091644080.031
regulation of neuron deathGO:1901214560.030
inflammatory responseGO:0006954790.030
ion homeostasisGO:00508012300.029
protein localization to organelleGO:00333652800.029
regulation of ion transmembrane transportGO:00347651320.029
single organism nuclear importGO:19025931040.029
protein autophosphorylationGO:00467771230.029
immune effector processGO:00022521590.029
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.029
signal transduction by phosphorylationGO:00230142970.029
negative regulation of catalytic activityGO:00430863350.028
system processGO:00030083490.028
nuclear exportGO:0051168690.027
protein targeting to nucleusGO:00447441040.027
receptor mediated endocytosisGO:0006898840.027
regulation of protein kinase activityGO:00458592890.027
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.027
regulation of establishment of protein localizationGO:00702012420.027
gmp metabolic processGO:004603740.027
nervous system developmentGO:00073992930.027
multi organism cellular processGO:00447641560.027
negative regulation of protein processingGO:00109551420.027
protein localization to nucleusGO:00345041360.027
small molecule biosynthetic processGO:00442831570.026
cell activationGO:00017752130.026
positive regulation of nucleotide biosynthetic processGO:0030810380.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
mitotic cell cycleGO:00002783260.026
regulation of cysteine type endopeptidase activityGO:20001161270.026
regulation of cellular component movementGO:00512703340.026
cell developmentGO:00484683280.026
negative regulation of neuron apoptotic processGO:0043524230.026
positive regulation of cell differentiationGO:00455972110.025
nuclear importGO:00511701060.025
de novo protein foldingGO:000645820.025
cellular cation homeostasisGO:00300031630.025
regulation of neuron apoptotic processGO:0043523350.025
spermatid differentiationGO:004851540.025
single organism cell adhesionGO:00986021790.024
cofactor metabolic processGO:0051186870.024
positive regulation of hydrolase activityGO:00513453310.024
negative regulation of phosphorus metabolic processGO:00105632670.024
regulation of transporter activityGO:0032409820.024
positive regulation of peptidase activityGO:0010952880.024
nucleic acid transportGO:0050657390.024
regulation of inflammatory responseGO:0050727460.024
positive regulation of immune system processGO:00026842830.024
ncrna metabolic processGO:00346601080.023
response to cytokineGO:00340972320.023
endocytosisGO:00068971590.023
gtp catabolic processGO:00061842370.023
positive regulation of cellular component movementGO:00512721810.023
nuclear divisionGO:00002801280.023
response to virusGO:00096151260.023
guanosine containing compound catabolic processGO:19010692390.023
positive regulation of innate immune responseGO:0045089790.022
leukocyte proliferationGO:0070661740.022
positive regulation of immune responseGO:00507781590.022
positive regulation of defense responseGO:0031349870.022
regulation of immune responseGO:00507762010.022
regulation of bindingGO:00510981110.022
reactive oxygen species metabolic processGO:0072593750.022
response to hormoneGO:00097251750.022
regulation of translational initiation in response to stressGO:004355810.022
regulation of innate immune responseGO:0045088970.022
cellular ion homeostasisGO:00068731680.022
cellular metal ion homeostasisGO:00068751460.022
regulation of protein targetingGO:1903533910.021
regulation of cell cycle processGO:00105642660.021
purine nucleoside monophosphate metabolic processGO:00091261860.021
regulation of cell motilityGO:20001452990.021
purine nucleoside catabolic processGO:00061523980.021
regulation of transmembrane transportGO:00347621390.021
regulation of protein maturationGO:19033171500.021
embryo developmentGO:00097901230.021
Worm
cellular macromolecular complex assemblyGO:00346223240.021
purine nucleoside monophosphate catabolic processGO:00091281580.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
nucleobase containing compound transportGO:0015931510.020
regulation of nucleotide biosynthetic processGO:0030808500.020
sex differentiationGO:0007548450.020
mononuclear cell proliferationGO:0032943710.020
rab protein signal transductionGO:003248240.020
calcium ion homeostasisGO:00550741220.020
negative regulation of endopeptidase activityGO:0010951840.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
cellular response to nitrogen compoundGO:19016991440.020
negative regulation of proteolysisGO:00458611320.020
protein catabolic processGO:00301633250.020
positive regulation of nucleotide metabolic processGO:00459812300.019
negative regulation of protein maturationGO:19033181420.019
regulation of ion transmembrane transporter activityGO:0032412720.019
regulation of anatomical structure morphogenesisGO:00226032860.019
immune response regulating signaling pathwayGO:0002764970.019
spindle assembly involved in mitosisGO:0090307120.019
regulation of purine nucleotide metabolic processGO:19005422640.019
mapk cascadeGO:00001652880.019
response to lipidGO:00339932060.019
heart processGO:0003015620.018
neuron deathGO:0070997650.018
cation transportGO:00068123310.018
cation transmembrane transportGO:00986552380.018
spermatid developmentGO:000728640.018
ras protein signal transductionGO:0007265730.018
reproductive processGO:00224141060.018
sulfur compound biosynthetic processGO:0044272380.018
regulation of cytoplasmic transportGO:19036491490.018
positive regulation of ion transportGO:0043270870.018
glial cell migrationGO:000834740.018
rna processingGO:00063962550.018
regulation of stress activated protein kinase signaling cascadeGO:0070302850.018
midbrain developmentGO:0030901450.018
blood circulationGO:00080151130.018
chemical homeostasisGO:00488783060.018
response to hyperoxiaGO:005509340.017
cellular respirationGO:0045333210.017
cellular divalent inorganic cation homeostasisGO:00725031280.017
activation of immune responseGO:00022531140.017
determination of adult lifespanGO:000834020.017
positive regulation of endopeptidase activityGO:0010950840.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.017
multicellular organismal agingGO:001025930.017
regulation of cellular ketone metabolic processGO:0010565500.017
negative regulation of intracellular transportGO:0032387600.017
establishment of protein localization to membraneGO:00901501210.017
positive regulation of apoptotic signaling pathwayGO:2001235700.017
carbohydrate derivative biosynthetic processGO:19011372070.016
organophosphate biosynthetic processGO:00904071630.016
hydrogen peroxide metabolic processGO:0042743200.016
regulation of secretion by cellGO:19035301770.016
regulation of dna metabolic processGO:00510521530.016
neuron apoptotic processGO:0051402390.016
lipid biosynthetic processGO:00086101770.016
regulation of protein localization to nucleusGO:1900180850.016
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.016
inorganic cation transmembrane transportGO:00986621940.016
negative regulation of phosphorylationGO:00423261740.016
negative regulation of organelle organizationGO:00106391260.016
ribonucleotide catabolic processGO:00092614050.016
monosaccharide metabolic processGO:0005996740.016
regulation of cell migrationGO:00303342890.016
positive regulation of protein transportGO:00512221350.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
lymphocyte activationGO:00466491330.015
single organism reproductive processGO:0044702980.015
positive regulation of protein phosphorylationGO:00019343130.015
activation of innate immune responseGO:0002218550.015
posttranscriptional regulation of gene expressionGO:00106082130.015
negative regulation of cell cycleGO:00457861930.015
monocarboxylic acid biosynthetic processGO:0072330670.015
cranial nerve developmentGO:002154540.015
cell growthGO:00160491600.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
negative regulation of neuron deathGO:1901215320.015
coenzyme metabolic processGO:0006732650.015
protein modification by small protein removalGO:0070646920.015
regulation of locomotionGO:00400123290.015
response to oxygen levelsGO:00704821000.014
ribonucleoprotein complex assemblyGO:0022618780.014
regulation of nucleoside metabolic processGO:00091182090.014
peptidyl serine phosphorylationGO:00181051010.014
regulation of multi organism processGO:00439001570.014
reproductive system developmentGO:0061458560.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
endomembrane system organizationGO:00102561960.014
regulation of growthGO:00400081650.014
positive regulation of cysteine type endopeptidase activityGO:2001056790.014
lymphocyte proliferationGO:0046651700.014
negative regulation of multi organism processGO:0043901920.014
detection of stimulusGO:0051606850.014
regulation of protein processingGO:00706131500.014
purine deoxyribonucleoside triphosphate metabolic processGO:000921540.014
cellular calcium ion homeostasisGO:00068741170.014
positive regulation of response to external stimulusGO:0032103880.014
regulation of transmembrane transporter activityGO:0022898740.014
protein oxidationGO:001815850.014
reproductive structure developmentGO:0048608550.014
activation of cysteine type endopeptidase activityGO:0097202570.013
regulation of lymphocyte activationGO:00512491030.013
negative regulation of cellular component organizationGO:00511292350.013
response to cocaineGO:004222010.013
protein foldingGO:0006457380.013
cell part morphogenesisGO:00329901370.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
neuron differentiationGO:00301821380.013
regulation of protein import into nucleusGO:0042306780.013
hydrogen peroxide catabolic processGO:0042744130.013
cellular component morphogenesisGO:00329893140.013
regulation of protein secretionGO:0050708860.013
detection of chemical stimulusGO:0009593550.013
zymogen activationGO:0031638700.013
positive regulation of nucleoside metabolic processGO:00459791860.013
negative regulation of protein modification processGO:00314002000.013
maintenance of locationGO:00512351120.013
negative regulation of protein transportGO:0051224750.013
organic hydroxy compound metabolic processGO:19016151470.013
stress activated mapk cascadeGO:0051403930.012
central nervous system developmentGO:00074171230.012
regulation of cell developmentGO:00602841610.012
ion transmembrane transportGO:00342203380.012
negative regulation of transferase activityGO:00513481240.012
cellular amide metabolic processGO:0043603690.012
protein homooligomerizationGO:00512601000.012
pattern recognition receptor signaling pathwayGO:0002221480.012
organelle fissionGO:00482851490.012
positive regulation of intracellular transportGO:00323881040.012
response to bacteriumGO:00096171440.012
leukocyte differentiationGO:0002521980.012
cellular response to organonitrogen compoundGO:00714171240.012
metal ion transportGO:00300012720.012
response to drugGO:0042493810.012
glycosyl compound biosynthetic processGO:1901659270.012
response to acid chemicalGO:0001101660.012
substantia nigra developmentGO:0021762450.012
cellular response to endogenous stimulusGO:00714953360.012
regulation of proteasomal protein catabolic processGO:0061136870.012
purine ribonucleoside triphosphate catabolic processGO:00092073910.012
ribose phosphate biosynthetic processGO:0046390820.012
mitotic cell cycle processGO:19030472860.012
protein oligomerizationGO:00512591730.012
positive regulation of purine nucleotide biosynthetic processGO:1900373380.012
ribonucleotide biosynthetic processGO:0009260810.012
heart contractionGO:0060047620.012
ameboidal type cell migrationGO:00016671350.012
cellular response to growth factor stimulusGO:00713631970.012
calcium ion transportGO:00068161470.012
cell substrate adhesionGO:00315891320.012
negative regulation of hydrolase activityGO:00513461820.012
negative regulation of kinase activityGO:00336731060.012
nerve developmentGO:002167540.012
cellular protein complex assemblyGO:00436231880.011
establishment of organelle localizationGO:0051656590.011
dna catabolic processGO:0006308490.011
divalent inorganic cation transportGO:00725111580.011
regulation of immune response to tumor cellGO:000283780.011
cellular amino acid biosynthetic processGO:0008652300.011
cell projection organizationGO:00300302520.011
organelle assemblyGO:00709251760.011
carbohydrate metabolic processGO:00059752070.011
positive regulation of phosphorylationGO:00423273940.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.011
negative regulation of response to external stimulusGO:0032102830.011
positive regulation of cell migrationGO:00303351720.011
divalent inorganic cation homeostasisGO:00725071360.011
innate immune response activating signal transductionGO:0002758480.011
negative regulation of intracellular signal transductionGO:19025321830.011
positive regulation of cellular catabolic processGO:00313312840.011
adult locomotory behaviorGO:000834410.011
neuromuscular junction developmentGO:000752830.011
rho protein signal transductionGO:0007266260.011
negative regulation of defense responseGO:0031348470.011
cofactor biosynthetic processGO:0051188310.011
neuron developmentGO:00486661130.011
growthGO:00400072020.011
regulation of cell substrate adhesionGO:0010810680.011
myeloid cell differentiationGO:00300991170.011
male sex differentiationGO:0046661250.011
regulation of membrane potentialGO:0042391950.011
response to reactive oxygen speciesGO:0000302610.011
regulation of mitosisGO:0007088630.010
inorganic ion transmembrane transportGO:00986602310.010
regulation of protein catabolic processGO:00421761550.010
regulation of dna bindingGO:0051101370.010
biological adhesionGO:00226103310.010
positive regulation of ras gtpase activityGO:00323201170.010
cell morphogenesisGO:00009022960.010
cell chemotaxisGO:00603261120.010
regulation of protein stabilityGO:0031647870.010
regulation of ras gtpase activityGO:00323181280.010
behaviorGO:00076101120.010
regulation of cellular response to growth factor stimulusGO:0090287760.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
positive regulation of cell motilityGO:20001471770.010
reproductionGO:0000003630.010
Worm
regulation of mitochondrion organizationGO:0010821540.010

PPA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
amino acid metabolic disorderDOID:9252500.346
inherited metabolic disorderDOID:6552420.346
disease of metabolismDOID:00146672950.346
immune system diseaseDOID:29141550.117
central nervous system diseaseDOID:3311860.054
nervous system diseaseDOID:8634310.054
disease of cellular proliferationDOID:145661740.039
cancerDOID:1621670.039
organ system cancerDOID:00506861640.039
hematopoietic system diseaseDOID:741000.013