| negative regulation of camp mediated signaling | GO:0043951 | 4 | 0.612 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.404 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.383 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.358 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.318 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.301 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.286 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.283 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.250 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.244 | |
| scf dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031146 | 15 | 0.234 | |
| protein ubiquitination | GO:0016567 | 314 | 0.214 | |
| protein catabolic process | GO:0030163 | 325 | 0.208 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.119 | |
| cyclic nucleotide mediated signaling | GO:0019935 | 26 | 0.075 | |
| camp mediated signaling | GO:0019933 | 23 | 0.067 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.065 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.061 | Mouse |
| nervous system development | GO:0007399 | 293 | 0.051 | |
| protein k48 linked ubiquitination | GO:0070936 | 38 | 0.051 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.048 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.046 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.042 | |
| regulation of camp mediated signaling | GO:0043949 | 13 | 0.042 | |
| protein monoubiquitination | GO:0006513 | 39 | 0.041 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.038 | Mouse |
| amine metabolic process | GO:0009308 | 44 | 0.038 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.038 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.037 | |
| second messenger mediated signaling | GO:0019932 | 78 | 0.035 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.034 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.033 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.033 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.032 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.031 | |
| segmentation | GO:0035282 | 4 | 0.031 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.031 | Fly |
| regulation of kinase activity | GO:0043549 | 314 | 0.030 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.028 | |
| regulation of triglyceride metabolic process | GO:0090207 | 11 | 0.028 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.028 | |
| lipid metabolic process | GO:0006629 | 381 | 0.025 | |
| hindbrain development | GO:0030902 | 3 | 0.025 | |
| chemical homeostasis | GO:0048878 | 306 | 0.024 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.024 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.024 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.024 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.024 | |
| metencephalon development | GO:0022037 | 2 | 0.023 | |
| somatic muscle development | GO:0007525 | 1 | 0.023 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.023 | |
| post embryonic development | GO:0009791 | 2 | 0.022 | |
| cell growth | GO:0016049 | 160 | 0.022 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.021 | |
| blood vessel morphogenesis | GO:0048514 | 162 | 0.021 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.021 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.021 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.020 | |
| locomotory behavior | GO:0007626 | 1 | 0.020 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.019 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.019 | |
| cerebellum development | GO:0021549 | 2 | 0.019 | |
| mapk cascade | GO:0000165 | 288 | 0.019 | |
| cell morphogenesis | GO:0000902 | 296 | 0.019 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.018 | |
| regulation of protein stability | GO:0031647 | 87 | 0.018 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.018 | |
| neurogenesis | GO:0022008 | 169 | 0.018 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.018 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.018 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.018 | |
| transmembrane transport | GO:0055085 | 399 | 0.017 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.017 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.017 | Mouse |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.017 | |
| growth | GO:0040007 | 202 | 0.017 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.017 | |
| defense response | GO:0006952 | 315 | 0.017 | |
| spermatid differentiation | GO:0048515 | 4 | 0.017 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.017 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.016 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.016 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.016 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.016 | |
| mitochondrion organization | GO:0007005 | 156 | 0.016 | |
| protein processing | GO:0016485 | 226 | 0.016 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.016 | |
| tor signaling | GO:0031929 | 39 | 0.016 | |
| female gamete generation | GO:0007292 | 2 | 0.016 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.015 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.015 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.015 | |
| organelle fission | GO:0048285 | 149 | 0.015 | Mouse |
| vasculature development | GO:0001944 | 181 | 0.015 | |
| lipid localization | GO:0010876 | 106 | 0.015 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.015 | |
| blastoderm segmentation | GO:0007350 | 2 | 0.015 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.014 | Fly |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.014 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.014 | |
| anterior posterior axis specification embryo | GO:0008595 | 2 | 0.014 | |
| cellular lipid catabolic process | GO:0044242 | 65 | 0.014 | |
| glycerolipid biosynthetic process | GO:0045017 | 51 | 0.014 | |
| oxidation reduction process | GO:0055114 | 396 | 0.014 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.014 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.014 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.014 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.014 | |
| regeneration | GO:0031099 | 4 | 0.014 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.014 | |
| system process | GO:0003008 | 349 | 0.014 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.014 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.014 | |
| cardiovascular system development | GO:0072358 | 262 | 0.014 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.013 | |
| metal ion transport | GO:0030001 | 272 | 0.013 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.013 | |
| response to fungus | GO:0009620 | 4 | 0.013 | |
| microtubule based process | GO:0007017 | 210 | 0.013 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.013 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.013 | |
| protein maturation | GO:0051604 | 233 | 0.013 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.013 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.013 | |
| organelle assembly | GO:0070925 | 176 | 0.013 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.013 | |
| protein localization to organelle | GO:0033365 | 280 | 0.013 | |
| cell projection organization | GO:0030030 | 252 | 0.013 | |
| circulatory system development | GO:0072359 | 262 | 0.013 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.013 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.013 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.013 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.013 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.012 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.012 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.012 | |
| response to radiation | GO:0009314 | 151 | 0.012 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.012 | |
| gtp metabolic process | GO:0046039 | 239 | 0.012 | |
| immune response | GO:0006955 | 307 | 0.012 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.012 | |
| regulation of actin filament based process | GO:0032970 | 141 | 0.012 | |
| maintenance of location | GO:0051235 | 112 | 0.012 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.012 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.012 | |
| endocytosis | GO:0006897 | 159 | 0.012 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.012 | |
| actin filament based process | GO:0030029 | 224 | 0.012 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.011 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.011 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.011 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.011 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.011 | |
| ion homeostasis | GO:0050801 | 230 | 0.011 | |
| rhythmic behavior | GO:0007622 | 2 | 0.011 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.011 | |
| regulation of cell growth | GO:0001558 | 135 | 0.011 | |
| dephosphorylation | GO:0016311 | 209 | 0.011 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.011 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.011 | |
| response to nutrient levels | GO:0031667 | 81 | 0.011 | |
| lipid transport | GO:0006869 | 90 | 0.011 | |
| negative regulation of glial cell proliferation | GO:0060253 | 2 | 0.011 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.011 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.011 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.011 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.011 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.011 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.011 | |
| regulation of immune response | GO:0050776 | 201 | 0.011 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.011 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 41 | 0.011 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.011 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 4 | 0.010 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.010 | |
| single organism cellular localization | GO:1902580 | 332 | 0.010 | |
| oocyte differentiation | GO:0009994 | 2 | 0.010 | |
| spermatid development | GO:0007286 | 4 | 0.010 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.010 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.010 | |
| nuclear transport | GO:0051169 | 179 | 0.010 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.010 | |
| neuron differentiation | GO:0030182 | 138 | 0.010 | |
| cellular homeostasis | GO:0019725 | 196 | 0.010 | |
| regulation of organelle assembly | GO:1902115 | 40 | 0.010 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.010 | |
| secretion by cell | GO:0032940 | 226 | 0.010 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.010 | |
| response to axon injury | GO:0048678 | 1 | 0.010 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.010 | |
| histone modification | GO:0016570 | 251 | 0.010 | |
| compound eye development | GO:0048749 | 1 | 0.010 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.010 | |
