Homo sapiens

68 known processes

ANKLE2

ankyrin repeat and LEM domain containing 2

(Aliases: LEMD7,KIAA0692,FLJ22280,FLJ36132)

ANKLE2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
multicellular organismal agingGO:001025930.124
post embryonic developmentGO:000979120.123
regulation of cell cycleGO:00517263930.101
cellular ketone metabolic processGO:0042180800.095
mitotic cell cycleGO:00002783260.092
female gamete generationGO:000729220.091
chromatin organizationGO:00063253510.085
oogenesisGO:004847720.083
mitotic cell cycle processGO:19030472860.080
cellular amino acid metabolic processGO:00065201160.077
vesicle mediated transportGO:00161923710.074
cellular amine metabolic processGO:0044106410.071
regulation of cellular amine metabolic processGO:0033238110.068
amine metabolic processGO:0009308440.068
regulation of cellular ketone metabolic processGO:0010565500.068
cellular macromolecule catabolic processGO:00442653800.067
regulation of cellular amino acid metabolic processGO:000652160.067
determination of adult lifespanGO:000834020.066
negative regulation of cell cycle processGO:00109481210.057
histone modificationGO:00165702510.057
chromatin modificationGO:00165682980.055
regulation of mitotic cell cycleGO:00073461890.055
positive regulation of phosphorylationGO:00423273940.054
small gtpase mediated signal transductionGO:0007264780.052
cell morphogenesisGO:00009022960.051
regulation of anatomical structure morphogenesisGO:00226032860.049
protein ubiquitinationGO:00165673140.049
regulation of protein localizationGO:00328802960.048
covalent chromatin modificationGO:00165692540.047
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
regulation of mitotic cell cycle phase transitionGO:19019901180.045
single organism membrane organizationGO:00448022680.045
positive regulation of protein phosphorylationGO:00019343130.044
regulation of cell cycle processGO:00105642660.044
regulation of kinase activityGO:00435493140.044
proteasomal protein catabolic processGO:00104981760.043
positive regulation of cellular amino acid metabolic processGO:004576430.043
cellular component morphogenesisGO:00329893140.043
proteolysis involved in cellular protein catabolic processGO:00516032440.042
negative regulation of phosphorus metabolic processGO:00105632670.040
modification dependent macromolecule catabolic processGO:00436322120.040
regulation of transferase activityGO:00513383550.040
regulation of cell differentiationGO:00455953930.040
cellular response to dna damage stimulusGO:00069743790.040
cell cycle phase transitionGO:00447701730.040
ras protein signal transductionGO:0007265730.040
actin filament based processGO:00300292240.039
membrane organizationGO:00610242920.039
negative regulation of cell cycleGO:00457861930.039
microtubule based processGO:00070172100.038
nervous system developmentGO:00073992930.037
lipid metabolic processGO:00066293810.037
mitotic cell cycle phase transitionGO:00447721620.037
positive regulation of cellular amine metabolic processGO:003324070.037
protein catabolic processGO:00301633250.037
protein localization to organelleGO:00333652800.036
regulation of cell cycle phase transitionGO:19019871260.036
modification dependent protein catabolic processGO:00199412090.036
endomembrane system organizationGO:00102561960.036
generation of neuronsGO:00486991520.035
protein modification by small protein conjugationGO:00324463420.035
negative regulation of catalytic activityGO:00430863350.035
positive regulation of protein kinase activityGO:00458601900.034
purine ribonucleoside metabolic processGO:00461284370.034
positive regulation of catabolic processGO:00098963100.034
purine containing compound catabolic processGO:00725234110.033
negative regulation of cellular component organizationGO:00511292350.033
positive regulation of hydrolase activityGO:00513453310.033
regulation of proteolysisGO:00301622930.033
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.033
cytoplasmic transportGO:00164823790.032
protein processingGO:00164852260.032
cellular macromolecular complex assemblyGO:00346223240.032
negative regulation of cellular protein metabolic processGO:00322693530.032
locomotory behaviorGO:000762610.032
positive regulation of cellular component organizationGO:00511303760.031
positive regulation of transferase activityGO:00513472270.031
dephosphorylationGO:00163112090.031
cell projection organizationGO:00300302520.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
stem cell divisionGO:001714520.030
negative regulation of developmental processGO:00510932470.030
purine ribonucleotide catabolic processGO:00091544040.030
ribonucleoside catabolic processGO:00424544060.030
regulation of cellular component movementGO:00512703340.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
negative regulation of cell cycle phase transitionGO:1901988890.029
regulation of cell morphogenesisGO:00226041530.029
peptidyl serine phosphorylationGO:00181051010.029
cell developmentGO:00484683280.028
cellular protein catabolic processGO:00442572610.028
regulation of cell motilityGO:20001452990.028
negative regulation of cell differentiationGO:00455961710.028
chromosome segregationGO:00070591140.028
cellular protein complex assemblyGO:00436231880.028
purine nucleoside triphosphate metabolic processGO:00091444120.027
negative regulation of mitotic cell cycle phase transitionGO:1901991850.027
positive regulation of cellular catabolic processGO:00313312840.027
neuron projection developmentGO:00311751060.027
cation transportGO:00068123310.027
mapk cascadeGO:00001652880.027
cell fate determinationGO:000170930.027
glycosyl compound catabolic processGO:19016584130.026
guanosine containing compound metabolic processGO:19010682440.026
negative regulation of mitotic cell cycleGO:00459301020.026
nucleoside catabolic processGO:00091644080.026
chemical homeostasisGO:00488783060.026
peptidyl serine modificationGO:00182091060.026
purine nucleoside triphosphate catabolic processGO:00091463920.025
biological adhesionGO:00226103310.025
nucleoside triphosphate metabolic processGO:00091414220.025
cell adhesionGO:00071553250.025
transmembrane transportGO:00550853990.025
apoptotic signaling pathwayGO:00971902680.025
response to abiotic stimulusGO:00096283360.025
carbohydrate derivative biosynthetic processGO:19011372070.025
signal transduction by phosphorylationGO:00230142970.025
regulation of cell migrationGO:00303342890.024
ribonucleotide catabolic processGO:00092614050.024
microtubule cytoskeleton organizationGO:00002261760.024
protein maturationGO:00516042330.024
purine nucleoside catabolic processGO:00061523980.024
protein dephosphorylationGO:0006470810.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of developmental processGO:00510943140.024
oocyte developmentGO:004859910.024
neuroblast proliferationGO:000740540.024
nucleoside triphosphate catabolic processGO:00091433940.024
single organism cellular localizationGO:19025803320.023
ubiquitin dependent protein catabolic processGO:00065112060.023
gtp metabolic processGO:00460392390.023
neuromuscular junction developmentGO:000752830.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
regulation of locomotionGO:00400123290.023
adult locomotory behaviorGO:000834410.023
regulation of response to external stimulusGO:00321012220.023
negative regulation of protein metabolic processGO:00512483910.023
cytokine productionGO:00018162470.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
actin cytoskeleton organizationGO:00300362070.023
regulation of establishment of protein localizationGO:00702012420.023
regulation of mapk cascadeGO:00434082620.023
spermatid differentiationGO:004851540.023
regulation of protein kinase activityGO:00458592890.023
segmentationGO:003528240.023
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.022
mitotic nuclear divisionGO:00070671190.022
cell morphogenesis involved in differentiationGO:00009041440.022
nucleotide catabolic processGO:00091664080.022
metal ion transportGO:00300012720.022
regulation of cell developmentGO:00602841610.022
oocyte differentiationGO:000999420.022
internal protein amino acid acetylationGO:00064751010.022
response to oxygen containing compoundGO:19017003690.022
purine nucleotide catabolic processGO:00061954050.022
ion transmembrane transportGO:00342203380.022
regenerationGO:003109940.021
positive regulation of transportGO:00510503360.021
protein localization to membraneGO:00726571600.021
posttranscriptional regulation of gene expressionGO:00106082130.021
negative regulation of phosphate metabolic processGO:00459362670.021
inorganic ion transmembrane transportGO:00986602310.021
chemotaxisGO:00069351570.021
rho protein signal transductionGO:0007266260.021
defense responseGO:00069523150.021
immune system developmentGO:00025201950.021
taxisGO:00423301570.020
negative regulation of cell deathGO:00605483450.020
negative regulation of cellular amine metabolic processGO:003323930.020
purine ribonucleoside catabolic processGO:00461303980.020
regulation of dna metabolic processGO:00510521530.020
regulation of cytokine productionGO:00018172320.020
blastoderm segmentationGO:000735020.020
negative regulation of protein modification processGO:00314002000.020
regulation of chromosome organizationGO:00330441030.020
negative regulation of phosphorylationGO:00423261740.020
protein acylationGO:00435431380.020
immune responseGO:00069553070.020
negative regulation of cell proliferationGO:00082852280.020
anterior posterior axis specificationGO:000994820.019
gtp catabolic processGO:00061842370.019
canonical wnt signaling pathwayGO:00600701160.019
carbohydrate metabolic processGO:00059752070.019
reactive oxygen species metabolic processGO:0072593750.019
spermatid developmentGO:000728640.019
intracellular protein transportGO:00068862700.019
cation transmembrane transportGO:00986552380.019
positive regulation of nucleotide metabolic processGO:00459812300.019
regulation of growthGO:00400081650.019
positive regulation of kinase activityGO:00336742040.019
nitrogen compound transportGO:00717051910.019
regulation of neural precursor cell proliferationGO:200017740.019
neurogenesisGO:00220081690.019
maintenance of locationGO:00512351120.019
response to growth factorGO:00708482050.019
axon regenerationGO:003110310.019
nucleoside phosphate catabolic processGO:19012924120.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
organelle assemblyGO:00709251760.018
regulation of purine nucleotide metabolic processGO:19005422640.018
negative regulation of multicellular organismal processGO:00512413170.018
neuron developmentGO:00486661130.018
wnt signaling pathwayGO:00160551560.018
actin filament organizationGO:00070151280.018
meiotic chromosome segregationGO:004513240.018
single organism carbohydrate metabolic processGO:00447231930.018
regulation of nucleotide metabolic processGO:00061402690.018
cell projection morphogenesisGO:00488581290.018
negative regulation of programmed cell deathGO:00430693210.018
negative regulation of intracellular signal transductionGO:19025321830.018
inorganic cation transmembrane transportGO:00986621940.018
mrna metabolic processGO:00160711750.018
positive regulation of cytokine productionGO:00018191670.017
histone acetylationGO:0016573930.017
negative regulation of apoptotic processGO:00430663160.017
peptidyl lysine modificationGO:00182051440.017
stem cell differentiationGO:0048863930.017
regulation of protein catabolic processGO:00421761550.017
cellular homeostasisGO:00197251960.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
response to oxidative stressGO:00069791210.017
dna replicationGO:00062601160.017
regulation of nucleoside metabolic processGO:00091182090.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
lipid biosynthetic processGO:00086101770.017
cell part morphogenesisGO:00329901370.017
protein autophosphorylationGO:00467771230.017
growthGO:00400072020.017
anion transportGO:00068201610.016
regulation of nucleotide catabolic processGO:00308112050.016
regulation of proteasomal protein catabolic processGO:0061136870.016
organophosphate catabolic processGO:00464344300.016
regulation of secretionGO:00510461940.016
cell growthGO:00160491600.016
cellular response to oxidative stressGO:0034599850.016
protein localization to nucleusGO:00345041360.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
positive regulation of mapk cascadeGO:00434101900.016
regulation of dephosphorylationGO:0035303960.016
negative regulation of hydrolase activityGO:00513461820.016
guanosine containing compound catabolic processGO:19010692390.016
positive regulation of organelle organizationGO:00106381950.016
organonitrogen compound biosynthetic processGO:19015662000.016
positive regulation of cell deathGO:00109422630.016
asymmetric stem cell divisionGO:009872210.016
memoryGO:000761330.016
positive regulation of cell proliferationGO:00082843010.016
cell divisionGO:00513011680.015
small molecule biosynthetic processGO:00442831570.015
regulation of cytoskeleton organizationGO:00514931770.015
negative regulation of transferase activityGO:00513481240.015
neuron projection regenerationGO:003110210.015
embryo developmentGO:00097901230.015
cellular chemical homeostasisGO:00550821800.015
peptidyl tyrosine phosphorylationGO:00181081700.015
regulation of immune responseGO:00507762010.015
response to fungusGO:000962040.015
morphogenesis of embryonic epitheliumGO:001633140.015
somatic stem cell divisionGO:004810310.015
regulation of cell morphogenesis involved in differentiationGO:0010769830.015
positive regulation of nucleoside metabolic processGO:00459791860.015
protein acetylationGO:00064731160.015
negative regulation of cell cycle g1 s phase transitionGO:1902807290.015
organic anion transportGO:00157111030.015
regulation of protein ubiquitinationGO:0031396950.015
endocytosisGO:00068971590.015
photoreceptor cell differentiationGO:004653020.015
regulation of axon guidanceGO:190266730.015
regulation of secretion by cellGO:19035301770.015
positive regulation of cell differentiationGO:00455972110.015
peripheral nervous system developmentGO:000742220.015
reactive nitrogen species metabolic processGO:200105730.015
hindbrain developmentGO:003090230.014
regulation of purine nucleotide catabolic processGO:00331212050.014
response to external biotic stimulusGO:00432072610.014
secretion by cellGO:00329402260.014
cell cycle checkpointGO:00000751170.014
regulation of protein transportGO:00512232130.014
reactive oxygen species biosynthetic processGO:190340940.014
organelle fissionGO:00482851490.014
secretionGO:00469032540.014
negative regulation of transportGO:00510511760.014
response to axon injuryGO:004867810.014
divalent metal ion transportGO:00708381520.014
neuron differentiationGO:00301821380.014
innate immune responseGO:00450871780.014
response to inorganic substanceGO:00100351270.014
autophagyGO:0006914880.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
regulation of cytoplasmic transportGO:19036491490.014
positive regulation of secretionGO:00510471160.014
regulation of cell cycle g1 s phase transitionGO:1902806420.014
regulation of protein serine threonine kinase activityGO:00719001790.014
neuronal stem cell divisionGO:003644510.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
establishment of protein localization to membraneGO:00901501210.014
nucleocytoplasmic transportGO:00069131760.014
response to radiationGO:00093141510.013
regulation of wnt signaling pathwayGO:00301111230.013
regulation of translationGO:0006417890.013
cellular response to growth factor stimulusGO:00713631970.013
response to other organismGO:00517072610.013
peptidyl lysine acetylationGO:00183941010.013
regulation of gtp catabolic processGO:00331241800.013
g1 s transition of mitotic cell cycleGO:0000082780.013
regulation of protein maturationGO:19033171500.013
negative regulation of protein processingGO:00109551420.013
peptidyl tyrosine modificationGO:00182121700.013
cellular response to oxygen containing compoundGO:19017012760.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
response to biotic stimulusGO:00096072760.013
single organism reproductive processGO:0044702980.013
rna interferenceGO:001624640.013
plasma membrane organizationGO:00070091150.013
defense response to fungusGO:005083240.013
positive regulation of programmed cell deathGO:00430682490.013
cellular response to endogenous stimulusGO:00714953360.013
cellular lipid metabolic processGO:00442553030.013
negative regulation of kinase activityGO:00336731060.013
regulation of neurogenesisGO:0050767820.013
glycoprotein metabolic processGO:00091001100.013
intracellular receptor signaling pathwayGO:00305221040.013
defense response to other organismGO:00985421290.013
dna repairGO:00062811980.013
neural tube formationGO:000184130.013
rna splicingGO:00083801310.013
positive regulation of apoptotic processGO:00430652460.013
protein localization to plasma membraneGO:0072659930.012
regulation of peptidase activityGO:00525471800.012
cardiac muscle cell contractionGO:008600340.012
regulation of homeostatic processGO:00328441210.012
mitotic cell cycle checkpointGO:0007093680.012
tripartite regional subdivisionGO:000735120.012
metencephalon developmentGO:002203720.012
regulation of ion transportGO:00432691890.012
reproductive processGO:00224141060.012
neurological system processGO:00508771630.012
rna processingGO:00063962550.012
neuroblast divisionGO:005505710.012
organ formationGO:004864530.012
dna damage checkpointGO:0000077680.012
regulation of g1 s transition of mitotic cell cycleGO:2000045400.012
negative regulation of cell migrationGO:00303361020.012
internal peptidyl lysine acetylationGO:0018393970.012
regulation of ras gtpase activityGO:00323181280.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of bindingGO:00510981110.012
motor neuron axon guidanceGO:000804520.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of lipid metabolic processGO:0019216960.012
regulation of cellular component biogenesisGO:00440872810.012
mitochondrion organizationGO:00070051560.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of vesicle mediated transportGO:00606271300.012
establishment of protein localization to organelleGO:00725941720.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
regulation of protein processingGO:00706131500.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
response to lipidGO:00339932060.012
regulation of gtpase activityGO:00430871800.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.012
regulation of cell projection organizationGO:00313441070.012
mitotic sister chromatid segregationGO:0000070530.012
regulation of chromatin organizationGO:1902275560.012
regulation of defense responseGO:00313471540.012
cellular response to abiotic stimulusGO:00712141170.012
cell activationGO:00017752130.012
nucleoside monophosphate metabolic processGO:00091231910.011
nucleus localizationGO:005164710.011
protein targetingGO:00066051870.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
circulatory system developmentGO:00723592620.011
regulation of intracellular transportGO:00323861950.011
compound eye developmentGO:004874910.011
cellular ion homeostasisGO:00068731680.011
thymus developmentGO:004853830.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
sister chromatid segregationGO:0000819540.011
divalent inorganic cation transportGO:00725111580.011
protein oligomerizationGO:00512591730.011
dna integrity checkpointGO:0031570710.011
positive regulation of cellular component movementGO:00512721810.011
system processGO:00030083490.011
syncytium formation by plasma membrane fusionGO:000076820.011
epithelium developmentGO:00604292270.011
regulation of actin filament based processGO:00329701410.011
metal ion homeostasisGO:00550651690.011
regulation of neuroblast proliferationGO:190269230.011
regulation of mitosisGO:0007088630.011
regulation of nervous system developmentGO:0051960880.011
hemopoiesisGO:00300971800.011
behaviorGO:00076101120.011
negative regulation of organelle organizationGO:00106391260.011
positive regulation of gtp catabolic processGO:00331261660.011
response to light stimulusGO:0009416870.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
positive regulation of locomotionGO:00400171860.011
negative regulation of locomotionGO:00400131180.011
ion homeostasisGO:00508012300.011
cation homeostasisGO:00550801890.011
actin filament based movementGO:0030048170.011
positive regulation of cell cycleGO:00457871400.011
calcium ion transportGO:00068161470.011
stress activated mapk cascadeGO:0051403930.011
reproductionGO:0000003630.011
positive regulation of gtpase activityGO:00435471660.011
regulation of apoptotic signaling pathwayGO:20012331750.011
negative regulation of proteolysisGO:00458611320.011
positive regulation of immune system processGO:00026842830.011
cell cycle arrestGO:0007050710.011
embryonic epithelial tube formationGO:000183840.011
cellular metal ion homeostasisGO:00068751460.010
divalent inorganic cation homeostasisGO:00725071360.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
cell cell signalingGO:00072671550.010
nerve developmentGO:002167540.010
protein polyubiquitinationGO:00002091100.010
anterior posterior axis specification embryoGO:000859520.010
positive regulation of cell migrationGO:00303351720.010
organic hydroxy compound metabolic processGO:19016151470.010
response to bacteriumGO:00096171440.010
nuclear divisionGO:00002801280.010
negative regulation of response to external stimulusGO:0032102830.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
establishment of protein localization to plasma membraneGO:0090002680.010
cellular cation homeostasisGO:00300031630.010
positive regulation of secretion by cellGO:19035321080.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
regulation of multi organism processGO:00439001570.010
lymphocyte activationGO:00466491330.010
alcohol metabolic processGO:00060661140.010

ANKLE2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.026
sensory system diseaseDOID:00501552030.016
nervous system diseaseDOID:8634310.016
cancerDOID:1621670.016
disease of cellular proliferationDOID:145661740.016
central nervous system diseaseDOID:3311860.015
organ system cancerDOID:00506861640.015
eye diseaseDOID:56141490.015
eye and adnexa diseaseDOID:14921500.015
neurodegenerative diseaseDOID:12891020.014
muscular diseaseDOID:00800001140.013
myopathyDOID:4231040.013
muscle tissue diseaseDOID:661130.013
disease of metabolismDOID:00146672950.013
bone diseaseDOID:0080001880.010
connective tissue diseaseDOID:651090.010