Homo sapiens

86 known processes

OPA1

optic atrophy 1 (autosomal dominant)

(Aliases: NPG,largeG,FLJ12460,MGM1,KIAA0567,NTG)

OPA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.556
Worm
female gamete generationGO:000729220.486
multicellular organismal agingGO:001025930.342
atp metabolic processGO:00460341760.308
oogenesisGO:004847720.308
ribonucleoside triphosphate metabolic processGO:00091994120.290
organophosphate catabolic processGO:00464344300.248
positive regulation of cellular component organizationGO:00511303760.237
nucleoside triphosphate metabolic processGO:00091414220.200
cellular component morphogenesisGO:00329893140.195
nucleoside triphosphate catabolic processGO:00091433940.182
organelle fissionGO:00482851490.176
cellular macromolecule catabolic processGO:00442653800.138
purine ribonucleoside monophosphate metabolic processGO:00091671860.138
purine ribonucleoside metabolic processGO:00461284370.135
purine ribonucleoside triphosphate metabolic processGO:00092054110.135
lipid metabolic processGO:00066293810.133
cell developmentGO:00484683280.132
ribonucleoside monophosphate catabolic processGO:00091581580.131
purine ribonucleoside monophosphate catabolic processGO:00091691580.131
purine ribonucleoside catabolic processGO:00461303980.124
determination of adult lifespanGO:000834020.124
purine nucleoside triphosphate metabolic processGO:00091444120.122
response to abiotic stimulusGO:00096283360.121
purine nucleoside triphosphate catabolic processGO:00091463920.118
establishment of organelle localizationGO:0051656590.116
cellular homeostasisGO:00197251960.115
cellular lipid metabolic processGO:00442553030.109
apoptotic mitochondrial changesGO:0008637570.108
protein catabolic processGO:00301633250.104
Worm
reactive oxygen species metabolic processGO:0072593750.104
mitochondrion organizationGO:00070051560.104
cell morphogenesisGO:00009022960.103
nucleoside catabolic processGO:00091644080.102
apoptotic signaling pathwayGO:00971902680.102
single organism membrane organizationGO:00448022680.095
vesicle mediated transportGO:00161923710.095
defense response to other organismGO:00985421290.093
defense responseGO:00069523150.093
ribonucleoside monophosphate metabolic processGO:00091611870.091
ribonucleoside catabolic processGO:00424544060.091
purine ribonucleotide catabolic processGO:00091544040.090
response to external biotic stimulusGO:00432072610.088
response to virusGO:00096151260.088
organelle fusionGO:0048284360.088
purine nucleotide catabolic processGO:00061954050.084
purine containing compound catabolic processGO:00725234110.082
mitotic cell cycle processGO:19030472860.081
microtubule based processGO:00070172100.081
microtubule cytoskeleton organizationGO:00002261760.080
cellular protein catabolic processGO:00442572610.080
single organism membrane fusionGO:0044801370.079
positive regulation of programmed cell deathGO:00430682490.079
membrane organizationGO:00610242920.079
purine nucleoside catabolic processGO:00061523980.078
regulation of membrane potentialGO:0042391950.076
ribonucleoside triphosphate catabolic processGO:00092033910.075
nucleoside monophosphate metabolic processGO:00091231910.075
cell projection organizationGO:00300302520.074
response to biotic stimulusGO:00096072760.074
purine ribonucleoside triphosphate catabolic processGO:00092073910.072
cellular macromolecular complex assemblyGO:00346223240.071
mitotic cell cycleGO:00002783260.070
meiotic chromosome segregationGO:004513240.069
cytoplasmic transportGO:00164823790.069
oocyte developmentGO:004859910.067
negative regulation of apoptotic processGO:00430663160.066
nuclear divisionGO:00002801280.066
cellular component disassemblyGO:0022411920.066
growthGO:00400072020.065
Worm
alcohol metabolic processGO:00060661140.064
cell morphogenesis involved in differentiationGO:00009041440.063
mitotic nuclear divisionGO:00070671190.063
chemical homeostasisGO:00488783060.062
single organism cellular localizationGO:19025803320.061
modification dependent macromolecule catabolic processGO:00436322120.061
intrinsic apoptotic signaling pathwayGO:00971931270.060
oocyte differentiationGO:000999420.060
organelle localizationGO:0051640840.060
chromosome segregationGO:00070591140.059
glycosyl compound catabolic processGO:19016584130.059
ion transmembrane transportGO:00342203380.056
inorganic ion transmembrane transportGO:00986602310.056
regulation of apoptotic signaling pathwayGO:20012331750.056
tube morphogenesisGO:0035239950.054
Mouse
nucleotide catabolic processGO:00091664080.053
sulfur compound metabolic processGO:00067901010.053
negative regulation of programmed cell deathGO:00430693210.053
purine nucleoside monophosphate catabolic processGO:00091281580.052
negative regulation of cell deathGO:00605483450.052
embryo developmentGO:00097901230.051
Mouse Worm
ubiquitin dependent protein catabolic processGO:00065112060.050
cell part morphogenesisGO:00329901370.050
response to organic cyclic compoundGO:00140702040.048
response to inorganic substanceGO:00100351270.048
Worm
regulation of system processGO:00440571010.048
regulation of cell cycleGO:00517263930.047
taxisGO:00423301570.046
small gtpase mediated signal transductionGO:0007264780.044
regulation of kinase activityGO:00435493140.044
negative regulation of catalytic activityGO:00430863350.043
regulation of protein localizationGO:00328802960.043
ribonucleotide catabolic processGO:00092614050.043
negative regulation of protein metabolic processGO:00512483910.043
dephosphorylationGO:00163112090.041
nucleoside phosphate catabolic processGO:19012924120.041
spindle organizationGO:0007051530.040
positive regulation of mitochondrial fissionGO:009014170.040
response to metal ionGO:0010038840.039
protein ubiquitinationGO:00165673140.039
regulation of homeostatic processGO:00328441210.039
spermatid differentiationGO:004851540.039
lipid modificationGO:0030258840.039
single organism carbohydrate metabolic processGO:00447231930.039
cation transmembrane transportGO:00986552380.038
nervous system developmentGO:00073992930.038
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.038
regulation of cellular amine metabolic processGO:0033238110.037
positive regulation of catabolic processGO:00098963100.037
regulation of growthGO:00400081650.037
Worm
positive regulation of cell deathGO:00109422630.037
metal ion transportGO:00300012720.036
cellular amino acid metabolic processGO:00065201160.036
transmembrane transportGO:00550853990.036
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.036
cellular response to growth factor stimulusGO:00713631970.036
inorganic cation transmembrane transportGO:00986621940.035
system processGO:00030083490.034
nucleoside monophosphate catabolic processGO:00091251590.034
protein modification by small protein conjugationGO:00324463420.034
neuron projection developmentGO:00311751060.034
protein complex disassemblyGO:0043241520.034
neuron differentiationGO:00301821380.033
digestionGO:0007586220.033
negative regulation of intracellular signal transductionGO:19025321830.033
metaphase plate congressionGO:0051310180.033
cell projection morphogenesisGO:00488581290.032
regulation of viral processGO:00507921030.032
positive regulation of cellular amine metabolic processGO:003324070.032
carbohydrate metabolic processGO:00059752070.032
dna repairGO:00062811980.032
positive regulation of apoptotic processGO:00430652460.031
regulation of anatomical structure morphogenesisGO:00226032860.031
positive regulation of apoptotic signaling pathwayGO:2001235700.031
nuclear importGO:00511701060.031
chromosome separationGO:0051304230.031
establishment of cell polarityGO:0030010220.030
response to nitrogen compoundGO:19016981840.030
oxidation reduction processGO:00551143960.029
negative regulation of organelle organizationGO:00106391260.029
cell growthGO:00160491600.029
ras protein signal transductionGO:0007265730.029
neurogenesisGO:00220081690.029
neuromuscular junction developmentGO:000752830.029
cellular response to dna damage stimulusGO:00069743790.029
fatty acid metabolic processGO:00066311150.028
spermatid developmentGO:000728640.028
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.028
proteasomal protein catabolic processGO:00104981760.028
monovalent inorganic cation transportGO:00156721280.027
regulation of meiotic cell cycleGO:005144540.027
intracellular protein transportGO:00068862700.027
cell divisionGO:00513011680.026
positive regulation of organelle organizationGO:00106381950.026
organic hydroxy compound metabolic processGO:19016151470.026
mitochondrial fragmentation involved in apoptotic processGO:004365370.026
amine metabolic processGO:0009308440.026
regulation of response to dna damage stimulusGO:2001020940.025
reproductionGO:0000003630.025
Worm
behaviorGO:00076101120.025
negative regulation of phosphate metabolic processGO:00459362670.024
single organism reproductive processGO:0044702980.024
chemotaxisGO:00069351570.024
peptidyl serine modificationGO:00182091060.024
regulation of mitochondrial fissionGO:009014080.024
cellular response to abiotic stimulusGO:00712141170.023
sister chromatid segregationGO:0000819540.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
cellular protein complex assemblyGO:00436231880.023
defense response to virusGO:0051607710.023
mitochondrial membrane organizationGO:0007006400.023
meiosis iGO:000712740.022
protein localization to organelleGO:00333652800.022
mitotic spindle organizationGO:0007052270.022
macromolecular complex disassemblyGO:0032984600.022
protein targetingGO:00066051870.022
glycerolipid metabolic processGO:00464861070.022
modification dependent protein catabolic processGO:00199412090.022
mitotic spindle elongationGO:000002240.022
immune effector processGO:00022521590.021
protein autophosphorylationGO:00467771230.021
regulation of multi organism processGO:00439001570.021
protein processingGO:00164852260.021
enzyme linked receptor protein signaling pathwayGO:00071673030.021
single organism nuclear importGO:19025931040.021
organ morphogenesisGO:00098871470.021
metal ion homeostasisGO:00550651690.021
neuron developmentGO:00486661130.020
reproductive processGO:00224141060.020
mitotic sister chromatid segregationGO:0000070530.020
positive regulation of intracellular transportGO:00323881040.020
spindle elongationGO:005123140.020
monocarboxylic acid metabolic processGO:00327871850.020
negative regulation of phosphorus metabolic processGO:00105632670.020
regulation of translationGO:0006417890.020
signal transduction by phosphorylationGO:00230142970.019
response to radiationGO:00093141510.019
establishment of protein localization to organelleGO:00725941720.019
protein polymerizationGO:0051258710.019
negative regulation of developmental processGO:00510932470.019
positive regulation of dna metabolic processGO:0051054730.019
granzyme mediated apoptotic signaling pathwayGO:000862640.019
viral life cycleGO:00190581320.019
digestive tract morphogenesisGO:0048546560.019
regulation of cytoskeleton organizationGO:00514931770.019
ion homeostasisGO:00508012300.018
response to uvGO:0009411730.018
response to light stimulusGO:0009416870.018
actin filament based movementGO:0030048170.018
regulation of protein kinase activityGO:00458592890.018
agingGO:0007568660.018
calcium ion homeostasisGO:00550741220.017
positive regulation of meiotic cell cycleGO:005144620.017
developmental growthGO:0048589480.017
Worm
positive regulation of protein transportGO:00512221350.017
establishment of protein localization to membraneGO:00901501210.017
regulation of protein maturationGO:19033171500.017
multi organism cellular processGO:00447641560.017
positive regulation of protein complex disassemblyGO:004324380.017
regulation of proteolysisGO:00301622930.017
organonitrogen compound biosynthetic processGO:19015662000.017
regulation of protein catabolic processGO:00421761550.017
regulation of cell morphogenesisGO:00226041530.017
protein oligomerizationGO:00512591730.017
response to growth factorGO:00708482050.017
viral processGO:00160321460.017
response to other organismGO:00517072610.016
cofactor metabolic processGO:0051186870.016
fat cell differentiationGO:0045444320.016
regulation of mitosisGO:0007088630.016
cellular ketone metabolic processGO:0042180800.016
axon developmentGO:0061564340.016
regenerationGO:003109940.016
positive regulation of proteolysisGO:00458621420.016
hindbrain developmentGO:003090230.016
glycerophospholipid metabolic processGO:0006650840.016
phospholipid metabolic processGO:0006644990.016
actin filament based processGO:00300292240.016
regulation of locomotionGO:00400123290.016
regulation of cell growthGO:00015581350.016
multicellular organismal reproductive processGO:0048609400.015
establishment of mitotic spindle localizationGO:004000180.015
establishment or maintenance of cytoskeleton polarityGO:003095230.015
regulation of protein processingGO:00706131500.015
positive regulation of protein kinase activityGO:00458601900.015
nuclear exportGO:0051168690.015
regulation of cellular component biogenesisGO:00440872810.015
atp catabolic processGO:00062001570.015
regulation of nuclear divisionGO:0051783650.015
nucleocytoplasmic transportGO:00069131760.015
cell type specific apoptotic processGO:00972851250.015
neuron projection morphogenesisGO:0048812500.015
regulation of vesicle mediated transportGO:00606271300.015
negative regulation of cellular component organizationGO:00511292350.015
regulation of transferase activityGO:00513383550.014
embryo development ending in birth or egg hatchingGO:0009792340.014
Mouse Worm
rna processingGO:00063962550.014
positive regulation of transferase activityGO:00513472270.014
response to oxygen containing compoundGO:19017003690.014
Worm
nucleus localizationGO:005164710.014
lipid transportGO:0006869900.014
negative regulation of proteolysisGO:00458611320.014
positive regulation of protein complex assemblyGO:0031334860.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
regulation of cell divisionGO:00513021160.014
positive regulation of phosphorylationGO:00423273940.014
cellular amine metabolic processGO:0044106410.014
endocytosisGO:00068971590.014
cell adhesionGO:00071553250.014
cellular response to endogenous stimulusGO:00714953360.014
cell cycle phase transitionGO:00447701730.014
cellular response to hormone stimulusGO:00328701250.013
membrane fusionGO:0061025430.013
biological adhesionGO:00226103310.013
regulation of mapk cascadeGO:00434082620.013
multi organism reproductive processGO:0044703540.013
posttranscriptional regulation of gene expressionGO:00106082130.013
rna interferenceGO:001624640.013
response to oxidative stressGO:00069791210.013
Worm
proteolysis involved in cellular protein catabolic processGO:00516032440.013
segmentationGO:003528240.013
mitotic sister chromatid separationGO:0051306180.013
positive regulation of cellular catabolic processGO:00313312840.013
regulation of mitotic cell cycleGO:00073461890.012
protein maturationGO:00516042330.012
wnt signaling pathwayGO:00160551560.012
tissue morphogenesisGO:0048729960.012
Mouse
purine nucleoside monophosphate metabolic processGO:00091261860.012
nuclear transportGO:00511691790.012
secretionGO:00469032540.012
defense response to bacteriumGO:0042742630.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
ribonucleoprotein complex biogenesisGO:00226131160.012
negative regulation of hydrolase activityGO:00513461820.012
tripartite regional subdivisionGO:000735120.012
compound eye developmentGO:004874910.012
regulation of cellular amino acid metabolic processGO:000652160.012
regulation of cellular component movementGO:00512703340.012
divalent inorganic cation transportGO:00725111580.012
positive regulation of cellular component biogenesisGO:00440891580.011
nuclear migrationGO:000709710.011
cation transportGO:00068123310.011
developmental process involved in reproductionGO:0003006660.011
generation of neuronsGO:00486991520.011
positive regulation of intracellular protein transportGO:0090316760.011
endosomal transportGO:00161971290.011
cellular metal ion homeostasisGO:00068751460.011
engulfment of apoptotic cellGO:004365220.011
establishment of nucleus localizationGO:004002310.011
protein dephosphorylationGO:0006470810.011
cellular response to nitrogen compoundGO:19016991440.011
protein importGO:00170381300.011
epithelium developmentGO:00604292270.011
Mouse
regulation of cell migrationGO:00303342890.011
organic acid transportGO:0015849650.011
regulation of cellular protein catabolic processGO:1903362960.011
regulation of response to external stimulusGO:00321012220.011
double strand break repairGO:00063021010.011
organophosphate biosynthetic processGO:00904071630.010
regulation of protein ubiquitinationGO:0031396950.010
mitochondrial transportGO:0006839600.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.010
regulation of cell cycle processGO:00105642660.010
regulation of dephosphorylationGO:0035303960.010
somitogenesisGO:000175620.010
regulation of meiosisGO:004002030.010
mrna metabolic processGO:00160711750.010
negative regulation of small gtpase mediated signal transductionGO:0051058120.010
positive regulation of kinase activityGO:00336742040.010
regulation of developmental growthGO:0048638300.010
Worm

OPA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.019
disease of cellular proliferationDOID:145661740.015
skin diseaseDOID:37330.015
integumentary system diseaseDOID:16430.015
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013