Homo sapiens

71 known processes

KLHL12

kelch-like 12 (Drosophila)

(Aliases: DKIR,C3IP1,FLJ27152)

KLHL12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
renal sodium ion absorptionGO:007029420.942
Human
sodium ion transportGO:0006814610.875
Human
protein k33 linked ubiquitinationGO:199039010.872
Human
chromosome passenger complex localization to spindle midzoneGO:003585310.854
Human
nephron epithelium morphogenesisGO:0072088150.832
Human
vesicle targeting rough er to cis golgiGO:004820720.829
copii vesicle coatingGO:004820820.749
modification dependent macromolecule catabolic processGO:00436322120.749
Human
distal tubule developmentGO:007201740.717
Human
nephron morphogenesisGO:0072028150.637
Human
protein monoubiquitinationGO:0006513390.627
nephron tubule morphogenesisGO:0072078130.624
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.618
Human
kidney developmentGO:0001822530.608
Human
ubiquitin dependent protein catabolic processGO:00065112060.592
Human
regulation of cell cycleGO:00517263930.586
Human
cellular macromolecule catabolic processGO:00442653800.540
Human
protein k48 linked ubiquitinationGO:0070936380.535
Human
protein modification by small protein conjugationGO:00324463420.501
kidney morphogenesisGO:0060993190.481
Human
monovalent inorganic cation transportGO:00156721280.435
Human
protein polyubiquitinationGO:00002091100.401
Human
vesicle targeting to from or within golgiGO:004819960.390
modification dependent protein catabolic processGO:00199412090.356
Human
proteasomal protein catabolic processGO:00104981760.354
Human
protein ubiquitinationGO:00165673140.352
membrane organizationGO:00610242920.313
tube morphogenesisGO:0035239950.304
Human
distal tubule morphogenesisGO:007215630.301
Human
protein catabolic processGO:00301633250.289
Human
regulation of cell differentiationGO:00455953930.278
actin filament based processGO:00300292240.243
posttranscriptional regulation of gene expressionGO:00106082130.209
Human
nephron epithelium developmentGO:0072009230.208
Human
cation transportGO:00068123310.191
Human
translationGO:00064121320.190
Human
anatomical structure formation involved in morphogenesisGO:00486462840.190
tissue morphogenesisGO:0048729960.184
Human Zebrafish
epithelium developmentGO:00604292270.182
Human Zebrafish
post golgi vesicle mediated transportGO:0006892360.179
Human
female gamete generationGO:000729220.177
ion homeostasisGO:00508012300.173
Human
translational initiationGO:0006413480.170
Human
chemical homeostasisGO:00488783060.145
Human
non canonical wnt signaling pathway via mapk cascadeGO:003803040.145
metal ion transportGO:00300012720.139
Human
negative regulation of programmed cell deathGO:00430693210.138
Human
tube developmentGO:00352951250.137
Human
renal tubule morphogenesisGO:0061333140.135
Human
blastoderm segmentationGO:000735020.133
endodermal cell fate commitmentGO:000171140.132
kidney epithelium developmentGO:0072073250.131
Human
regulation of cell divisionGO:00513021160.128
Human
renal system processGO:0003014250.126
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.125
regulation of translationGO:0006417890.123
Human
vesicle mediated transportGO:00161923710.114
protein localization to organelleGO:00333652800.108
Human
negative regulation of protein metabolic processGO:00512483910.105
Human
nephron developmentGO:0072006300.099
Human
regulation of transferase activityGO:00513383550.094
negative regulation of cellular protein metabolic processGO:00322693530.094
Human
nephron tubule developmentGO:0072080170.093
Human
cellular protein catabolic processGO:00442572610.090
Human
actin cytoskeleton organizationGO:00300362070.089
lipid localizationGO:00108761060.089
golgi vesicle transportGO:0048193800.088
oogenesisGO:004847720.087
maintenance of locationGO:00512351120.086
regulation of cytokinesisGO:0032465450.085
Human
cellular protein complex localizationGO:003462980.083
Human
endodermal cell fate specificationGO:000171440.083
regulation of cell developmentGO:00602841610.083
regulation of protein catabolic processGO:00421761550.081
vesicle coatingGO:000690190.081
lipid biosynthetic processGO:00086101770.080
cell developmentGO:00484683280.080
canonical wnt signaling pathway involved in heart developmentGO:006131630.079
single organism membrane organizationGO:00448022680.078
somatic stem cell maintenanceGO:003501940.075
cellular lipid metabolic processGO:00442553030.073
anterior posterior axis specificationGO:000994820.071
regulation of cellular ketone metabolic processGO:0010565500.070
regulation of translational initiationGO:0006446240.067
Human
vesicle organizationGO:0016050620.067
cellular amino acid metabolic processGO:00065201160.064
cellular ketone metabolic processGO:0042180800.062
cytoplasmic transportGO:00164823790.059
system processGO:00030083490.058
Human
positive regulation of cellular amino acid metabolic processGO:004576430.056
negative regulation of apoptotic processGO:00430663160.055
Human
regulation of cell cycle processGO:00105642660.055
Human
single organism cellular localizationGO:19025803320.054
cellular amine metabolic processGO:0044106410.053
regulation of protein kinase activityGO:00458592890.052
protein oligomerizationGO:00512591730.052
response to inorganic substanceGO:00100351270.051
organ morphogenesisGO:00098871470.049
Human
nervous system developmentGO:00073992930.048
er to golgi vesicle mediated transportGO:0006888190.048
generation of neuronsGO:00486991520.046
regulation of proteasomal protein catabolic processGO:0061136870.046
segmentationGO:003528240.046
positive regulation of protein phosphorylationGO:00019343130.045
heart field specificationGO:000312820.045
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.045
positive regulation of cell differentiationGO:00455972110.045
long term memoryGO:000761620.045
protein complex localizationGO:0031503310.045
Human
photoreceptor cell differentiationGO:004653020.044
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.044
Human
mapk cascadeGO:00001652880.043
monocarboxylic acid metabolic processGO:00327871850.043
neurogenesisGO:00220081690.042
regulation of nervous system developmentGO:0051960880.042
post embryonic developmentGO:000979120.041
regulation of cytoskeleton organizationGO:00514931770.039
memoryGO:000761330.039
associative learningGO:000830610.039
positive regulation of phosphorylationGO:00423273940.038
regulation of actin filament based processGO:00329701410.037
amine metabolic processGO:0009308440.037
cell projection organizationGO:00300302520.036
negative regulation of cell deathGO:00605483450.036
Human
negative regulation of translationGO:0017148370.035
Human
organelle localizationGO:0051640840.035
regulation of cellular amino acid metabolic processGO:000652160.034
cell fate commitment involved in pattern specificationGO:006058110.033
positive regulation of proteasomal protein catabolic processGO:1901800350.033
phototransduction visible lightGO:000760320.033
small molecule biosynthetic processGO:00442831570.033
single organism reproductive processGO:0044702980.033
regulation of apoptotic signaling pathwayGO:20012331750.033
organ formationGO:004864530.033
negative regulation of kinase activityGO:00336731060.032
regulation of cellular component biogenesisGO:00440872810.032
negative regulation of cell proliferationGO:00082852280.032
rna polyadenylationGO:0043631140.032
negative regulation of response to external stimulusGO:0032102830.032
positive regulation of cellular component organizationGO:00511303760.032
formation of primary germ layerGO:0001704420.032
actin filament bundle organizationGO:0061572540.031
regulation of kinase activityGO:00435493140.031
response to other organismGO:00517072610.031
cell divisionGO:00513011680.031
Human
negative regulation of cellular component organizationGO:00511292350.031
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.030
neuromuscular junction developmentGO:000752830.030
regulation of receptor mediated endocytosisGO:0048259320.030
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.030
regulation of cellular amine metabolic processGO:0033238110.030
receptor internalizationGO:0031623430.030
specification of organ identityGO:001009230.030
viral processGO:00160321460.030
regulation of neurogenesisGO:0050767820.029
negative regulation of cell fate commitmentGO:001045430.029
positive regulation of protein catabolic processGO:0045732750.029
outflow tract septum morphogenesisGO:000314840.028
muscle cell fate commitmentGO:004269340.028
lipid metabolic processGO:00066293810.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
apoptotic signaling pathwayGO:00971902680.028
cytokinesisGO:0000910960.028
Human
determination of adult lifespanGO:000834020.027
regulation of protein bindingGO:0043393660.027
regulation of heart morphogenesisGO:200082640.027
regulation of actin cytoskeleton organizationGO:00329561160.027
regulation of endocytosisGO:0030100720.027
lipid storageGO:0019915280.027
regulation of protein localizationGO:00328802960.026
non canonical wnt signaling pathway via jnk cascadeGO:003803130.026
negative regulation of intracellular signal transductionGO:19025321830.026
neural tube formationGO:000184130.026
negative regulation of phosphorylationGO:00423261740.026
nitrogen compound transportGO:00717051910.025
multicellular organismal agingGO:001025930.025
vesicle localizationGO:0051648260.024
regulation of vesicle mediated transportGO:00606271300.024
receptor metabolic processGO:0043112810.024
positive regulation of cellular amine metabolic processGO:003324070.024
tripartite regional subdivisionGO:000735120.024
negative regulation of protein modification processGO:00314002000.024
cell fate determinationGO:000170930.024
regulation of heart inductionGO:009038120.024
inner ear morphogenesisGO:004247240.023
cochlea developmentGO:009010210.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
digestive system developmentGO:0055123750.023
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.023
Human
rna export from nucleusGO:0006405330.022
transmembrane transportGO:00550853990.022
negative regulation of transportGO:00510511760.022
organic acid biosynthetic processGO:0016053970.022
limbic system developmentGO:002176130.022
negative regulation of phosphorus metabolic processGO:00105632670.022
negative regulation of catalytic activityGO:00430863350.022
negative regulation of cellular amino acid metabolic processGO:004576320.021
cell projection morphogenesisGO:00488581290.021
positive regulation of developmental processGO:00510943140.021
anterior posterior axis specification embryoGO:000859520.021
endosomal transportGO:00161971290.021
Human
mitotic cell cycleGO:00002783260.020
establishment of planar polarityGO:000173630.020
positive regulation of proteolysisGO:00458621420.020
embryonic epithelial tube formationGO:000183840.020
protein secretionGO:0009306980.020
negative regulation of phosphate metabolic processGO:00459362670.020
reproductive processGO:00224141060.020
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.020
neuron differentiationGO:00301821380.020
localization within membraneGO:0051668140.020
positive regulation of neurogenesisGO:0050769490.019
dephosphorylationGO:00163112090.019
regulation of cellular protein catabolic processGO:1903362960.019
positive regulation of transferase activityGO:00513472270.019
actin filament bundle assemblyGO:0051017540.019
regulation of meiosisGO:004002030.019
multi organism reproductive processGO:0044703540.019
regulation of response to external stimulusGO:00321012220.019
heart developmentGO:0007507950.018
organ inductionGO:000175940.018
salivary gland morphogenesisGO:000743540.018
regulation of proteolysisGO:00301622930.018
primary neural tube formationGO:001402030.018
retinal ganglion cell axon guidanceGO:003129020.018
regulation of homeostatic processGO:00328441210.018
establishment of apical basal cell polarityGO:003508910.018
negative regulation of apoptotic signaling pathwayGO:2001234970.018
positive regulation of catabolic processGO:00098963100.018
regulation of wnt signaling pathwayGO:00301111230.018
response to uvGO:0009411730.017
response to radiationGO:00093141510.017
response to abiotic stimulusGO:00096283360.017
cell morphogenesisGO:00009022960.017
rna interferenceGO:001624640.017
heart formationGO:006091420.017
regulation of ion homeostasisGO:2000021730.017
digestive tract developmentGO:0048565750.017
negative regulation of cell fate specificationGO:000999630.017
cell fate specificationGO:000170880.017
nucleobase containing compound transportGO:0015931510.017
response to external biotic stimulusGO:00432072610.017
positive regulation of kinase activityGO:00336742040.017
ras protein signal transductionGO:0007265730.017
protein autophosphorylationGO:00467771230.017
mitochondrion organizationGO:00070051560.016
negative regulation of multi organism processGO:0043901920.016
cellular response to metal ionGO:0071248430.016
positive regulation of cellular catabolic processGO:00313312840.016
rna processingGO:00063962550.016
spermatid developmentGO:000728640.016
rna transportGO:0050658390.016
purine ribonucleoside catabolic processGO:00461303980.016
rho protein signal transductionGO:0007266260.016
muscle structure developmentGO:0061061980.016
actin filament organizationGO:00070151280.016
positive regulation of cellular protein catabolic processGO:1903364370.016
response to oxygen containing compoundGO:19017003690.016
tor signalingGO:0031929390.016
viral life cycleGO:00190581320.015
axis elongationGO:000340140.015
Zebrafish
negative regulation of cell differentiationGO:00455961710.015
gastrulationGO:0007369510.015
protein autoubiquitinationGO:0051865370.015
organelle fissionGO:00482851490.015
regulation of organ formationGO:000315640.015
motor neuron axon guidanceGO:000804520.015
neuron developmentGO:00486661130.015
positive regulation of nervous system developmentGO:0051962540.015
cellular response to dna damage stimulusGO:00069743790.015
spermatid differentiationGO:004851540.015
digestive tract morphogenesisGO:0048546560.015
regulation of isoprenoid metabolic processGO:001974710.015
mrna polyadenylationGO:0006378120.015
multicellular organismal reproductive processGO:0048609400.015
tube closureGO:006060630.015
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.015
organophosphate biosynthetic processGO:00904071630.014
multi organism cellular processGO:00447641560.014
protein localization to nucleusGO:00345041360.014
neural tube closureGO:000184330.014
sexual reproductionGO:0019953370.014
negative regulation of cellular amine metabolic processGO:003323930.014
positive regulation of protein kinase activityGO:00458601900.014
protein targetingGO:00066051870.014
response to fungusGO:000962040.014
regulation of meiotic cell cycleGO:005144540.014
cardiovascular system developmentGO:00723582620.014
positive regulation of wnt signaling pathwayGO:0030177540.014
neurotransmitter secretionGO:000726940.014
negative regulation of immune system processGO:00026831360.014
lens development in camera type eyeGO:000208820.014
compound eye developmentGO:004874910.014
regulation of neural precursor cell proliferationGO:200017740.014
postsynaptic membrane organizationGO:000194120.014
negative regulation of transferase activityGO:00513481240.014
actomyosin structure organizationGO:0031032590.014
embryo developmentGO:00097901230.014
gtp metabolic processGO:00460392390.014
regulation of defense responseGO:00313471540.014
morphogenesis of embryonic epitheliumGO:001633140.013
ribonucleoside catabolic processGO:00424544060.013
regulation of cellular response to stressGO:00801352440.013
defense response to other organismGO:00985421290.013
establishment of protein localization to membraneGO:00901501210.013
nucleotide catabolic processGO:00091664080.013
phototransductionGO:000760230.013
cell growthGO:00160491600.013
stress fiber assemblyGO:0043149400.013
forebrain regionalizationGO:002187130.013
forebrain generation of neuronsGO:002187230.013
positive regulation of cell proliferationGO:00082843010.013
regulation of cardioblast differentiationGO:005189040.013
establishment of protein localization to organelleGO:00725941720.013
cardiac muscle cell contractionGO:008600340.013
regulation of notch signaling pathwayGO:0008593180.013
negative regulation of protein phosphorylationGO:00019331400.013
developmental process involved in reproductionGO:0003006660.013
establishment or maintenance of monopolar cell polarityGO:006133910.013
interspecies interaction between organismsGO:00444191560.013
positive regulation of dendrite morphogenesisGO:005077530.013
regulation of membrane potentialGO:0042391950.013
oxidation reduction processGO:00551143960.013
establishment or maintenance of bipolar cell polarityGO:006124520.012
regulation of cell adhesionGO:00301551660.012
regulation of multi organism processGO:00439001570.012
late endosome to vacuole transportGO:004532420.012
secretionGO:00469032540.012
regulation of bindingGO:00510981110.012
sodium ion transmembrane transportGO:0035725590.012
defense responseGO:00069523150.012
purine ribonucleoside triphosphate metabolic processGO:00092054110.012
rna splicingGO:00083801310.012
ribonucleoprotein complex biogenesisGO:00226131160.012
nuclear transportGO:00511691790.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
visual learningGO:000854210.012
wnt signaling pathwayGO:00160551560.012
ribonucleoside triphosphate metabolic processGO:00091994120.012
cellular cation homeostasisGO:00300031630.012
regulation of protein serine threonine kinase activityGO:00719001790.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.012
circulatory system developmentGO:00723592620.012
ribonucleoprotein complex subunit organizationGO:0071826810.012
type b pancreatic cell developmentGO:000332340.012
positive regulation of neuron differentiationGO:0045666400.012
positive regulation of canonical wnt signaling pathwayGO:0090263330.012
cellular response to oxygen containing compoundGO:19017012760.012
multicellular organism reproductionGO:0032504420.012
macroautophagyGO:0016236390.012
protein localization to membraneGO:00726571600.012
negative regulation of protein kinase activityGO:0006469980.012
plasma membrane organizationGO:00070091150.012
negative regulation of catabolic processGO:00098951040.012
mrna 3 end processingGO:0031124240.012
locomotory behaviorGO:000762610.012
inorganic ion transmembrane transportGO:00986602310.011
monocarboxylic acid biosynthetic processGO:0072330670.011
ribonucleotide catabolic processGO:00092614050.011
reproductionGO:0000003630.011
regulation of rna splicingGO:0043484620.011
growthGO:00400072020.011
Zebrafish
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.011
dendritic spine morphogenesisGO:006099730.011
establishment of tissue polarityGO:000716430.011
urogenital system developmentGO:0001655650.011
Human
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of intracellular transportGO:00323861950.011
notch signaling pathwayGO:0007219310.011
regulation of cardioblast cell fate specificationGO:004268610.011
regulation of ossificationGO:0030278580.011
negative regulation of protein processingGO:00109551420.011
cation homeostasisGO:00550801890.011
hippocampus developmentGO:002176610.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
nucleoside catabolic processGO:00091644080.011
mrna metabolic processGO:00160711750.011
mrna splicing via spliceosomeGO:0000398890.011
nucleic acid transportGO:0050657390.011
cardioblast cell fate commitmentGO:004268410.011
coenzyme metabolic processGO:0006732650.010
regulation of membrane depolarizationGO:0003254190.010
protein acylationGO:00435431380.010
response to metal ionGO:0010038840.010
convergent extensionGO:006002610.010
Zebrafish
regulation of ion transportGO:00432691890.010
response to nutrient levelsGO:0031667810.010
regulation of stress activated mapk cascadeGO:0032872840.010
response to cytokineGO:00340972320.010
regulation of actin filament bundle assemblyGO:0032231360.010
fatty acid biosynthetic processGO:0006633460.010
ncrna metabolic processGO:00346601080.010
cardioblast cell fate specificationGO:004268510.010
eye photoreceptor cell differentiationGO:000175420.010
myosin filament assemblyGO:003103420.010
regulation of growthGO:00400081650.010
neuron projection developmentGO:00311751060.010
cellular chemical homeostasisGO:00550821800.010
cellular response to radiationGO:0071478650.010
adult locomotory behaviorGO:000834410.010
visual behaviorGO:000763220.010
heart inductionGO:000312940.010
organonitrogen compound biosynthetic processGO:19015662000.010
regulation of cytoplasmic transportGO:19036491490.010

KLHL12 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:14921500.022
eye diseaseDOID:56141490.022
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
musculoskeletal system diseaseDOID:172230.015
myopathyDOID:4231040.015
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
disease of metabolismDOID:00146672950.012