Homo sapiens

138 known processes

PAF1

Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)

(Aliases: F23149_1,PD2,FLJ11123)

PAF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of dna templated transcription elongationGO:0032786180.999
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.961
histone h2b ubiquitinationGO:003352380.955
histone monoubiquitinationGO:0010390200.862
regulation of dna templated transcription elongationGO:0032784230.785
transcription elongation from rna polymerase ii promoterGO:0006368180.764
regulation of cellular component biogenesisGO:00440872810.665
chromatin organizationGO:00063253510.650
chromatin modificationGO:00165682980.613
mrna processingGO:00063971330.607
regulation of transcription elongation from rna polymerase ii promoterGO:0034243130.578
rna processingGO:00063962550.540
protein monoubiquitinationGO:0006513390.530
protein methylationGO:0006479740.443
hematopoietic or lymphoid organ developmentGO:00485341860.438
post embryonic developmentGO:000979120.435
mrna metabolic processGO:00160711750.420
covalent chromatin modificationGO:00165692540.418
mrna 3 end processingGO:0031124240.412
myeloid cell differentiationGO:00300991170.411
cellular response to dna damage stimulusGO:00069743790.408
regulation of mrna 3 end processingGO:0031440120.404
histone ubiquitinationGO:0016574310.350
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.318
protein ubiquitinationGO:00165673140.311
hemopoiesisGO:00300971800.282
phosphorylation of rna polymerase ii c terminal domainGO:007081630.265
digestive system developmentGO:0055123750.265
trophectodermal cell differentiationGO:000182930.263
dna templated transcription elongationGO:0006354250.258
vesicle mediated transportGO:00161923710.238
positive regulation of chromosome organizationGO:2001252410.236
positive regulation of cellular amino acid metabolic processGO:004576430.234
regulation of cellular amine metabolic processGO:0033238110.233
endodermal cell fate commitmentGO:000171140.221
regulation of chromatin organizationGO:1902275560.212
nucleic acid phosphodiester bond hydrolysisGO:00903051020.211
regulation of cellular response to stressGO:00801352440.210
positive regulation of cellular component organizationGO:00511303760.210
genetic imprintingGO:007151410.195
cell cycle phase transitionGO:00447701730.194
cellular amine metabolic processGO:0044106410.192
negative regulation of myeloid cell differentiationGO:0045638420.192
protein modification by small protein conjugationGO:00324463420.185
ncrna processingGO:0034470830.184
embryonic morphogenesisGO:0048598850.182
nucleotide excision repairGO:0006289310.176
rna splicingGO:00083801310.176
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.167
mitotic cell cycleGO:00002783260.161
cellular amino acid metabolic processGO:00065201160.160
muscle system processGO:0003012810.159
regulation of mrna metabolic processGO:1903311530.153
rna 3 end processingGO:0031123350.149
histone modificationGO:00165702510.148
positive regulation of mrna metabolic processGO:1903313190.148
dna templated transcription initiationGO:0006352350.142
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.134
gastrulationGO:0007369510.131
digestive tract developmentGO:0048565750.127
regulation of myeloid cell differentiationGO:0045637810.126
peptidyl lysine methylationGO:0018022370.126
blastocyst developmentGO:000182430.123
negative regulation of multicellular organismal processGO:00512413170.123
amine metabolic processGO:0009308440.120
histone methylationGO:0016571600.115
regulation of cellular amino acid metabolic processGO:000652160.110
regulation of cellular ketone metabolic processGO:0010565500.109
erythrocyte differentiationGO:0030218280.109
methylationGO:00322591060.107
regulation of cell differentiationGO:00455953930.104
positive regulation of histone modificationGO:0031058290.101
negative regulation of developmental processGO:00510932470.098
negative regulation of cell differentiationGO:00455961710.093
immune system developmentGO:00025201950.093
positive regulation of catabolic processGO:00098963100.092
response to bacteriumGO:00096171440.091
dna repairGO:00062811980.090
positive regulation of developmental processGO:00510943140.089
cellular response to cytokine stimulusGO:00713451810.087
peptidyl lysine trimethylationGO:0018023100.084
regulation of mrna processingGO:0050684480.084
macromolecule methylationGO:0043414970.081
mitotic cell cycle processGO:19030472860.078
histone h3 k4 methylationGO:0051568270.077
cellular response to molecule of bacterial originGO:0071219620.075
cellular response to lipopolysaccharideGO:0071222570.074
protein alkylationGO:0008213740.071
regulation of cell cycleGO:00517263930.069
endocytosisGO:00068971590.068
embryo developmentGO:00097901230.068
segmentationGO:003528240.067
purine nucleotide catabolic processGO:00061954050.066
cellular response to oxygen containing compoundGO:19017012760.065
response to external biotic stimulusGO:00432072610.065
negative regulation of immune system processGO:00026831360.064
regulation of cell cycle processGO:00105642660.064
cell developmentGO:00484683280.062
cellular macromolecular complex assemblyGO:00346223240.057
purine nucleoside catabolic processGO:00061523980.056
cellular ketone metabolic processGO:0042180800.054
muscle contractionGO:0006936730.052
stem cell differentiationGO:0048863930.052
growthGO:00400072020.052
dna damage checkpointGO:0000077680.048
ncrna metabolic processGO:00346601080.048
regulation of histone modificationGO:0031056470.048
negative regulation of cell cycle processGO:00109481210.048
anatomical structure formation involved in morphogenesisGO:00486462840.047
cell fate commitment involved in formation of primary germ layerGO:006079560.047
positive regulation of protein complex assemblyGO:0031334860.046
positive regulation of cellular amine metabolic processGO:003324070.046
negative regulation of mitotic cell cycle phase transitionGO:1901991850.045
protein catabolic processGO:00301633250.045
regulation of chromosome organizationGO:00330441030.044
system processGO:00030083490.044
dephosphorylationGO:00163112090.044
positive regulation of organelle organizationGO:00106381950.044
regulation of rna splicingGO:0043484620.043
regulation of locomotionGO:00400123290.043
nucleoside catabolic processGO:00091644080.043
regulation of protein complex assemblyGO:00432541470.042
regulation of mitotic cell cycleGO:00073461890.042
formation of primary germ layerGO:0001704420.041
purine ribonucleoside triphosphate metabolic processGO:00092054110.040
transcription from rna polymerase iii promoterGO:0006383190.039
positive regulation of gtpase activityGO:00435471660.039
transcription from rna polymerase i promoterGO:0006360110.039
cellular response to external stimulusGO:00714961110.039
negative regulation of cell cycleGO:00457861930.039
rna splicing via transesterification reactionsGO:0000375900.038
regulation of transcription by chromatin organizationGO:003440110.038
macroautophagyGO:0016236390.038
cytoplasmic transportGO:00164823790.038
response to biotic stimulusGO:00096072760.038
regulation of cellular component movementGO:00512703340.038
nucleoside triphosphate catabolic processGO:00091433940.037
purine ribonucleoside catabolic processGO:00461303980.037
mitotic cell cycle phase transitionGO:00447721620.036
organophosphate catabolic processGO:00464344300.036
gene silencingGO:0016458490.036
receptor mediated endocytosisGO:0006898840.036
cell divisionGO:00513011680.036
modification dependent protein catabolic processGO:00199412090.035
purine nucleoside triphosphate metabolic processGO:00091444120.035
cytokine mediated signaling pathwayGO:00192211090.035
dna integrity checkpointGO:0031570710.034
nervous system developmentGO:00073992930.034
dna biosynthetic processGO:0071897400.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
regulation of response to dna damage stimulusGO:2001020940.033
microtubule based processGO:00070172100.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
nuclear divisionGO:00002801280.032
regulation of kinase activityGO:00435493140.032
protein complex disassemblyGO:0043241520.032
positive regulation of hydrolase activityGO:00513453310.031
histone h4 k16 acetylationGO:0043984140.031
positive regulation of purine nucleotide catabolic processGO:00331231850.031
positive regulation of cellular catabolic processGO:00313312840.031
regulation of cell migrationGO:00303342890.031
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589830.031
tube developmentGO:00352951250.031
positive regulation of protein phosphorylationGO:00019343130.030
positive regulation of mrna processingGO:0050685170.030
mitotic cell cycle checkpointGO:0007093680.030
positive regulation of mrna 3 end processingGO:0031442120.030
negative regulation of cell cycle phase transitionGO:1901988890.030
nucleotide catabolic processGO:00091664080.030
positive regulation of transcription from rna polymerase i promoterGO:004594360.030
positive regulation of chromatin modificationGO:1903310300.030
jak stat cascadeGO:0007259460.030
digestive tract morphogenesisGO:0048546560.030
regulation of purine nucleotide metabolic processGO:19005422640.029
positive regulation of wnt signaling pathwayGO:0030177540.029
peptidyl lysine acetylationGO:00183941010.029
response to lipidGO:00339932060.028
dna templated transcription terminationGO:000635330.028
regulation of transferase activityGO:00513383550.027
protein dephosphorylationGO:0006470810.027
response to nutrient levelsGO:0031667810.027
regulation of histone methylationGO:0031060160.027
purine ribonucleoside metabolic processGO:00461284370.027
ribonucleoside catabolic processGO:00424544060.026
cellular response to nutrient levelsGO:0031669690.026
regulation of nucleotide metabolic processGO:00061402690.026
peptidyl lysine modificationGO:00182051440.026
internal protein amino acid acetylationGO:00064751010.026
regulation of wnt signaling pathwayGO:00301111230.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
negative regulation of cellular protein metabolic processGO:00322693530.025
response to oxygen containing compoundGO:19017003690.025
positive regulation of phosphorylationGO:00423273940.025
protein polyubiquitinationGO:00002091100.024
transcription initiation from rna polymerase ii promoterGO:0006367270.024
regulation of cell motilityGO:20001452990.024
positive regulation of transportGO:00510503360.024
negative regulation of protein metabolic processGO:00512483910.024
photoreceptor cell differentiationGO:004653020.024
mrna splicing via spliceosomeGO:0000398890.024
regulation of growthGO:00400081650.024
ribonucleotide catabolic processGO:00092614050.024
cardiac muscle cell contractionGO:008600340.024
regulation of protein kinase activityGO:00458592890.023
female gamete generationGO:000729220.023
striated muscle contractionGO:0006941520.023
regulation of nucleotide catabolic processGO:00308112050.023
histone acetylationGO:0016573930.023
negative regulation of transcription elongation from rna polymerase ii promoterGO:003424440.023
rrna processingGO:0006364350.023
generation of neuronsGO:00486991520.023
purine containing compound catabolic processGO:00725234110.023
cellular response to starvationGO:0009267580.023
stem cell developmentGO:0048864690.022
spermatid developmentGO:000728640.022
oocyte developmentGO:004859910.022
negative regulation of apoptotic processGO:00430663160.022
erythrocyte developmentGO:004882130.022
cellular protein catabolic processGO:00442572610.022
cellular macromolecule catabolic processGO:00442653800.022
cellular response to endogenous stimulusGO:00714953360.022
negative regulation of cell deathGO:00605483450.022
organelle fissionGO:00482851490.022
multicellular organismal agingGO:001025930.022
negative regulation of cell proliferationGO:00082852280.022
negative regulation of mitotic cell cycleGO:00459301020.022
blastoderm segmentationGO:000735020.021
meiotic chromosome segregationGO:004513240.021
reproductive processGO:00224141060.021
regulation of autophagyGO:0010506520.021
protein acetylationGO:00064731160.021
positive regulation of nucleotide metabolic processGO:00459812300.021
cell cycle checkpointGO:00000751170.021
positive regulation of gtp catabolic processGO:00331261660.021
g2 dna damage checkpointGO:0031572260.021
negative regulation of cell migrationGO:00303361020.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
embryo development ending in birth or egg hatchingGO:0009792340.021
response to interleukin 6GO:0070741150.020
negative regulation of cell motilityGO:20001461040.020
protein acylationGO:00435431380.020
negative regulation of programmed cell deathGO:00430693210.020
nucleoside triphosphate metabolic processGO:00091414220.020
regulation of dna metabolic processGO:00510521530.020
positive regulation of growthGO:0045927580.020
glycosyl compound catabolic processGO:19016584130.020
regulation of histone acetylationGO:0035065190.020
purine ribonucleotide catabolic processGO:00091544040.020
regulation of nucleoside metabolic processGO:00091182090.019
dna replicationGO:00062601160.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
rho protein signal transductionGO:0007266260.019
ubiquitin dependent protein catabolic processGO:00065112060.019
ribonucleoprotein complex biogenesisGO:00226131160.019
neurogenesisGO:00220081690.019
gtp catabolic processGO:00061842370.019
positive regulation of smoothened signaling pathwayGO:004588040.019
cellular response to interleukin 6GO:0071354140.019
regulation of transcription from rna polymerase i promoterGO:0006356100.019
response to other organismGO:00517072610.019
mitotic nuclear divisionGO:00070671190.018
negative regulation of cellular component movementGO:00512711060.018
negative regulation of catalytic activityGO:00430863350.018
endodermal cell differentiationGO:0035987310.018
associative learningGO:000830610.018
rrna metabolic processGO:0016072400.018
ncrna 3 end processingGO:004362840.017
neuron developmentGO:00486661130.017
neuromuscular junction developmentGO:000752830.017
actin filament based movementGO:0030048170.017
regulation of epithelial cell proliferationGO:00506781130.017
secretion by cellGO:00329402260.017
regulation of dna templated transcription initiationGO:200014290.017
locomotory behaviorGO:000762610.017
guanosine containing compound catabolic processGO:19010692390.017
nuclear migrationGO:000709710.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
lipid metabolic processGO:00066293810.017
positive regulation of programmed cell deathGO:00430682490.017
response to hormoneGO:00097251750.017
cell fate determinationGO:000170930.017
positive regulation of cell deathGO:00109422630.017
modification dependent macromolecule catabolic processGO:00436322120.017
positive regulation of response to external stimulusGO:0032103880.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
viral processGO:00160321460.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.016
spermatid differentiationGO:004851540.016
positive regulation of nucleotide catabolic processGO:00308131850.016
negative regulation of locomotionGO:00400131180.016
ribonucleoprotein complex subunit organizationGO:0071826810.016
atp metabolic processGO:00460341760.016
negative regulation of cellular amine metabolic processGO:003323930.016
embryonic hindlimb morphogenesisGO:003511620.016
stem cell maintenanceGO:0019827190.016
reproductionGO:0000003630.016
establishment of nucleus localizationGO:004002310.016
guanosine containing compound metabolic processGO:19010682440.016
spindle organizationGO:0007051530.016
dna templated transcriptional preinitiation complex assemblyGO:007089750.016
regulation of mitotic cell cycle phase transitionGO:19019901180.016
positive regulation of secretionGO:00510471160.016
ras protein signal transductionGO:0007265730.016
microtubule cytoskeleton organizationGO:00002261760.016
biological adhesionGO:00226103310.016
regulation of vesicle mediated transportGO:00606271300.015
maintenance of locationGO:00512351120.015
gtp metabolic processGO:00460392390.015
nucleoside phosphate catabolic processGO:19012924120.015
monocarboxylic acid metabolic processGO:00327871850.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
negative regulation of phosphorylationGO:00423261740.015
response to abiotic stimulusGO:00096283360.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
viral life cycleGO:00190581320.015
regulation of gtpase activityGO:00430871800.015
regulation of purine nucleotide catabolic processGO:00331212050.015
lens development in camera type eyeGO:000208820.015
visual learningGO:000854210.015
wnt signaling pathwayGO:00160551560.015
homeostasis of number of cellsGO:0048872400.015
oocyte differentiationGO:000999420.015
regenerationGO:003109940.015
oogenesisGO:004847720.015
regulation of synaptic plasticityGO:004816730.015
metal ion transportGO:00300012720.015
regulation of protein stabilityGO:0031647870.015
regulation of gtp catabolic processGO:00331241800.014
mapk cascadeGO:00001652880.014
negative regulation of cell cycle g1 s phase transitionGO:1902807290.014
tube morphogenesisGO:0035239950.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of protein processingGO:00706131500.014
postreplication repairGO:0006301120.014
cellular response to biotic stimulusGO:0071216710.014
chemotaxisGO:00069351570.014
autophagyGO:0006914880.014
dna conformation changeGO:00711031130.014
peptidyl lysine dimethylationGO:001802730.014
cellular response to growth factor stimulusGO:00713631970.014
reactive oxygen species metabolic processGO:0072593750.014
histone h4 acetylationGO:0043967470.014
cell morphogenesisGO:00009022960.013
actin mediated cell contractionGO:0070252120.013
cellular response to extracellular stimulusGO:0031668720.013
immune responseGO:00069553070.013
thymus developmentGO:004853830.013
response to radiationGO:00093141510.013
cell cycle g1 s phase transitionGO:0044843800.013
rna polyadenylationGO:0043631140.013
regulation of secretionGO:00510461940.013
translesion synthesisGO:001998580.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
regulation of chromatin silencingGO:003193580.013
regulation of response to external stimulusGO:00321012220.013
regulation of meiosisGO:004002030.013
nucleosome organizationGO:0034728660.013
histone h3 k79 methylationGO:003472920.013
macromolecular complex disassemblyGO:0032984600.013
regulation of transporter activityGO:0032409820.013
secretionGO:00469032540.013
positive regulation of nucleoside metabolic processGO:00459791860.013
cellular protein complex assemblyGO:00436231880.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
neuroblast proliferationGO:000740540.013
negative regulation of cellular component organizationGO:00511292350.013
cell growthGO:00160491600.013
peripheral nervous system developmentGO:000742220.012
cellular lipid metabolic processGO:00442553030.012
protein stabilizationGO:0050821640.012
reactive nitrogen species metabolic processGO:200105730.012
g1 s transition of mitotic cell cycleGO:0000082780.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
golgi vesicle transportGO:0048193800.012
protein localization to organelleGO:00333652800.012
meiosis iGO:000712740.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
regulation of transcription during mitosisGO:004589620.012
osteoblast differentiationGO:0001649920.012
small gtpase mediated signal transductionGO:0007264780.012
positive regulation of histone methylationGO:0031062120.012
neurotransmitter secretionGO:000726940.012
negative regulation of camp mediated signalingGO:004395140.012
hormone metabolic processGO:0042445610.012
alcohol metabolic processGO:00060661140.012
apoptotic signaling pathwayGO:00971902680.012
compound eye developmentGO:004874910.012
positive regulation of apoptotic processGO:00430652460.012
blood vessel morphogenesisGO:00485141620.012
interspecies interaction between organismsGO:00444191560.012
membrane organizationGO:00610242920.012
response to fungusGO:000962040.012
adult locomotory behaviorGO:000834410.012
central nervous system developmentGO:00074171230.012
regulation of dna repairGO:0006282470.012
neurological system processGO:00508771630.011
cell projection morphogenesisGO:00488581290.011
negative regulation of protein processingGO:00109551420.011
peptidyl tyrosine phosphorylationGO:00181081700.011
anterior posterior axis specificationGO:000994820.011
response to extracellular stimulusGO:0009991850.011
mrna transcriptionGO:000929980.011
eye photoreceptor cell differentiationGO:000175420.011
regulation of cell cycle phase transitionGO:19019871260.011
memoryGO:000761330.011
matingGO:000761810.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
regulation of proteolysisGO:00301622930.011
protein processingGO:00164852260.011
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.011
lipid transportGO:0006869900.011
determination of adult lifespanGO:000834020.011
embryonic hemopoiesisGO:003516240.011
rna localizationGO:0006403410.011
positive regulation of cell migrationGO:00303351720.011
steroid metabolic processGO:0008202940.011
histone h4 k8 acetylationGO:0043982150.011
positive regulation of cellular component movementGO:00512721810.011
protein dna complex assemblyGO:0065004640.011
regulation of intracellular transportGO:00323861950.011
regulation of mapk cascadeGO:00434082620.011
regulation of meiotic cell cycleGO:005144540.011
single organism reproductive processGO:0044702980.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
somatic stem cell maintenanceGO:003501940.010
regulation of response to drugGO:200102330.010
amino acid activationGO:0043038120.010
peptidyl tyrosine modificationGO:00182121700.010
positive regulation of kinase activityGO:00336742040.010
positive regulation of cell motilityGO:20001471770.010
regulation of establishment of protein localizationGO:00702012420.010
histone lysine methylationGO:0034968500.010
regulation of macroautophagyGO:0016241190.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.010
establishment or maintenance of apical basal cell polarityGO:003508820.010
reactive oxygen species biosynthetic processGO:190340940.010
regulation of transcription initiation from rna polymerase ii promoterGO:006026080.010
organic hydroxy compound metabolic processGO:19016151470.010
negative regulation of proteolysisGO:00458611320.010
rna interferenceGO:001624640.010

PAF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
endocrine gland cancerDOID:170260.197
cancerDOID:1621670.197
disease of cellular proliferationDOID:145661740.197
organ system cancerDOID:00506861640.197
nervous system diseaseDOID:8634310.040
sensory system diseaseDOID:00501552030.040
eye diseaseDOID:56141490.040
eye and adnexa diseaseDOID:14921500.040
usher syndromeDOID:0050439120.020
musculoskeletal system diseaseDOID:172230.016
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
central nervous system diseaseDOID:3311860.012
retinal degenerationDOID:8466890.011
retinal diseaseDOID:56791180.011
myopathyDOID:4231040.011
brain diseaseDOID:936730.010