Homo sapiens

120 known processes

SPAST

spastin

(Aliases: ADPSP,SPG4,KIAA1083,FSP2)

SPAST biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517263930.102
growthGO:00400072020.092
Zebrafish Fly
macromolecule methylationGO:0043414970.081
methylationGO:00322591060.080
purine containing compound catabolic processGO:00725234110.068
cell morphogenesisGO:00009022960.063
Zebrafish Fly
nucleoside catabolic processGO:00091644080.060
ribonucleoside monophosphate catabolic processGO:00091581580.059
carbohydrate metabolic processGO:00059752070.057
atp catabolic processGO:00062001570.052
female gamete generationGO:000729220.051
regulation of growthGO:00400081650.050
Zebrafish Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
purine ribonucleoside triphosphate catabolic processGO:00092073910.045
negative regulation of cell deathGO:00605483450.044
Zebrafish
negative regulation of cellular protein metabolic processGO:00322693530.042
microtubule based processGO:00070172100.041
nucleoside phosphate catabolic processGO:19012924120.041
nucleoside triphosphate catabolic processGO:00091433940.041
ribonucleoside triphosphate metabolic processGO:00091994120.039
secretion by cellGO:00329402260.038
tissue migrationGO:00901301190.038
regulation of anatomical structure morphogenesisGO:00226032860.037
Zebrafish Fly
purine nucleoside monophosphate metabolic processGO:00091261860.036
mitotic cell cycle processGO:19030472860.035
Fly
locomotory behaviorGO:000762610.035
Fly
ribonucleotide catabolic processGO:00092614050.035
nucleoside monophosphate catabolic processGO:00091251590.035
protein modification by small protein conjugationGO:00324463420.034
cellular component morphogenesisGO:00329893140.034
Zebrafish Fly
purine nucleoside triphosphate metabolic processGO:00091444120.033
cellular macromolecular complex assemblyGO:00346223240.033
ameboidal type cell migrationGO:00016671350.033
multi organism cellular processGO:00447641560.032
oocyte developmentGO:004859910.032
purine ribonucleoside monophosphate catabolic processGO:00091691580.031
mitotic cell cycleGO:00002783260.031
Fly
regulation of transferase activityGO:00513383550.031
regulation of multi organism processGO:00439001570.031
response to oxygen containing compoundGO:19017003690.031
regulation of developmental growthGO:0048638300.031
Zebrafish Fly
cellular response to growth factor stimulusGO:00713631970.031
oogenesisGO:004847720.030
response to growth factorGO:00708482050.029
enzyme linked receptor protein signaling pathwayGO:00071673030.029
developmental growthGO:0048589480.028
Zebrafish Fly
neuromuscular junction developmentGO:000752830.028
Fly
chemical homeostasisGO:00488783060.028
regulation of cell cycle processGO:00105642660.028
microtubule cytoskeleton organizationGO:00002261760.027
nucleotide catabolic processGO:00091664080.027
dephosphorylationGO:00163112090.026
cellular homeostasisGO:00197251960.026
ribonucleoside catabolic processGO:00424544060.026
viral processGO:00160321460.026
positive regulation of transportGO:00510503360.026
vesicle mediated transportGO:00161923710.025
regulation of cellular component biogenesisGO:00440872810.025
Fly
ribonucleoside monophosphate metabolic processGO:00091611870.025
organophosphate catabolic processGO:00464344300.024
cell part morphogenesisGO:00329901370.024
Zebrafish Fly
endocytosisGO:00068971590.024
negative regulation of phosphate metabolic processGO:00459362670.024
rna processingGO:00063962550.024
nucleoside monophosphate metabolic processGO:00091231910.023
cell projection organizationGO:00300302520.023
Zebrafish Fly
purine ribonucleoside monophosphate metabolic processGO:00091671860.023
purine nucleoside triphosphate catabolic processGO:00091463920.023
negative regulation of protein metabolic processGO:00512483910.023
dna repairGO:00062811980.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
cellular protein complex assemblyGO:00436231880.022
negative regulation of catalytic activityGO:00430863350.022
regulation of cellular amino acid metabolic processGO:000652160.022
negative regulation of multicellular organismal processGO:00512413170.022
Fly
defense responseGO:00069523150.021
interspecies interaction between organismsGO:00444191560.020
amine metabolic processGO:0009308440.020
positive regulation of developmental processGO:00510943140.020
Zebrafish Fly
response to other organismGO:00517072610.020
purine ribonucleotide catabolic processGO:00091544040.020
regulation of kinase activityGO:00435493140.019
negative regulation of phosphorus metabolic processGO:00105632670.019
cellular amino acid metabolic processGO:00065201160.019
regulation of viral processGO:00507921030.019
regulation of protein kinase activityGO:00458592890.019
regulation of mapk cascadeGO:00434082620.018
positive regulation of developmental growthGO:0048639160.018
Zebrafish Fly
purine ribonucleoside catabolic processGO:00461303980.018
response to abiotic stimulusGO:00096283360.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
nucleoside triphosphate metabolic processGO:00091414220.017
negative regulation of intracellular signal transductionGO:19025321830.017
negative regulation of phosphorylationGO:00423261740.017
segmentationGO:003528240.017
glycosyl compound catabolic processGO:19016584130.017
positive regulation of cellular amine metabolic processGO:003324070.017
regulation of cell differentiationGO:00455953930.017
Zebrafish Fly
regulation of cell morphogenesisGO:00226041530.017
Zebrafish Fly
cellular response to dna damage stimulusGO:00069743790.016
protein catabolic processGO:00301633250.016
signal transduction by phosphorylationGO:00230142970.016
oocyte differentiationGO:000999420.016
positive regulation of cell proliferationGO:00082843010.016
protein localization to organelleGO:00333652800.016
endosomal transportGO:00161971290.016
spermatid developmentGO:000728640.016
positive regulation of immune system processGO:00026842830.016
negative regulation of protein modification processGO:00314002000.016
cytoplasmic transportGO:00164823790.016
response to radiationGO:00093141510.015
negative regulation of programmed cell deathGO:00430693210.015
Zebrafish
purine ribonucleoside metabolic processGO:00461284370.015
membrane organizationGO:00610242920.015
regulation of cellular component sizeGO:0032535820.015
Zebrafish
positive regulation of cell differentiationGO:00455972110.015
Zebrafish Fly
epithelium migrationGO:00901321190.015
negative regulation of protein phosphorylationGO:00019331400.015
regulation of cell developmentGO:00602841610.015
Zebrafish Fly
ribonucleoside triphosphate catabolic processGO:00092033910.015
response to external biotic stimulusGO:00432072610.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
cytokine productionGO:00018162470.014
protein dephosphorylationGO:0006470810.014
negative regulation of cell differentiationGO:00455961710.014
positive regulation of locomotionGO:00400171860.014
cellular amine metabolic processGO:0044106410.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
spermatid differentiationGO:004851540.014
negative regulation of transferase activityGO:00513481240.014
post embryonic developmentGO:000979120.014
neuron projection morphogenesisGO:0048812500.014
Zebrafish Fly
embryo developmentGO:00097901230.013
Fly
mrna metabolic processGO:00160711750.013
neuron projection developmentGO:00311751060.013
Zebrafish Fly
regulation of dna metabolic processGO:00510521530.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
regulation of cell motilityGO:20001452990.013
organelle localizationGO:0051640840.013
meiotic chromosome segregationGO:004513240.013
regulation of cell migrationGO:00303342890.013
cellular ketone metabolic processGO:0042180800.013
protein ubiquitinationGO:00165673140.013
long term memoryGO:000761620.013
carbohydrate derivative biosynthetic processGO:19011372070.012
response to hormoneGO:00097251750.012
cellular protein catabolic processGO:00442572610.012
regulation of cellular amine metabolic processGO:0033238110.012
chromatin modificationGO:00165682980.012
chromatin organizationGO:00063253510.012
rna interferenceGO:001624640.012
covalent chromatin modificationGO:00165692540.012
organelle assemblyGO:00709251760.012
cell developmentGO:00484683280.012
Zebrafish Fly
cell morphogenesis involved in differentiationGO:00009041440.012
Zebrafish Fly
response to virusGO:00096151260.012
regulation of cytoskeleton organizationGO:00514931770.012
Zebrafish Fly
cellular macromolecule catabolic processGO:00442653800.012
regulation of cell divisionGO:00513021160.012
regulation of gene expression epigeneticGO:0040029730.012
cellular response to endogenous stimulusGO:00714953360.012
negative regulation of apoptotic processGO:00430663160.012
Zebrafish
immune responseGO:00069553070.012
peptidyl lysine acetylationGO:00183941010.012
glycoprotein biosynthetic processGO:0009101910.012
positive regulation of cell migrationGO:00303351720.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
Zebrafish Fly
negative regulation of immune system processGO:00026831360.011
transmembrane transportGO:00550853990.011
mitotic cell cycle phase transitionGO:00447721620.011
positive regulation of cellular component organizationGO:00511303760.011
Zebrafish Fly
single organism cellular localizationGO:19025803320.011
glycoprotein metabolic processGO:00091001100.011
positive regulation of proteolysisGO:00458621420.011
multicellular organismal agingGO:001025930.011
protein glycosylationGO:0006486620.011
reproductive processGO:00224141060.011
cell adhesionGO:00071553250.011
positive regulation of transferase activityGO:00513472270.011
cellular response to oxygen containing compoundGO:19017012760.011
atp metabolic processGO:00460341760.011
negative regulation of cellular component organizationGO:00511292350.011
Fly
generation of neuronsGO:00486991520.011
Zebrafish Fly
mapk cascadeGO:00001652880.011
cellular carbohydrate metabolic processGO:0044262840.011
taxisGO:00423301570.011
determination of adult lifespanGO:000834020.011
negative regulation of kinase activityGO:00336731060.011
modification dependent macromolecule catabolic processGO:00436322120.010
protein methylationGO:0006479740.010
centrosome organizationGO:0051297580.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
cell growthGO:00160491600.010
Zebrafish
protein targetingGO:00066051870.010
alcohol metabolic processGO:00060661140.010
cell cycle checkpointGO:00000751170.010
negative regulation of cell cycleGO:00457861930.010

SPAST disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
central nervous system diseaseDOID:3311860.017
musculoskeletal system diseaseDOID:172230.014
connective tissue diseaseDOID:651090.014
bone diseaseDOID:0080001880.014
disease of metabolismDOID:00146672950.013
paraplegiaDOID:607190.001
hereditary spastic paraplegiaDOID:2476190.001